AR006192A1 - RADIOPHARMACEUTICAL COMPLEXES AND SET OF ELEMENTS TO PREPARE SUCH COMPLEXES - Google Patents

RADIOPHARMACEUTICAL COMPLEXES AND SET OF ELEMENTS TO PREPARE SUCH COMPLEXES

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Publication number
AR006192A1
AR006192A1 ARP970100975A ARP970100975A AR006192A1 AR 006192 A1 AR006192 A1 AR 006192A1 AR P970100975 A ARP970100975 A AR P970100975A AR P970100975 A ARP970100975 A AR P970100975A AR 006192 A1 AR006192 A1 AR 006192A1
Authority
AR
Argentina
Prior art keywords
complexes
radiopharmaceutical
chelator
prepare
elements
Prior art date
Application number
ARP970100975A
Other languages
Spanish (es)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of AR006192A1 publication Critical patent/AR006192A1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Provee nuevos complejos radiofarmacéuticos y un conjunto de elementos (kits) para preparar dichos complejos. Estos complejos son útiles comoagentes de detección de imágenes en el diagnóstico de afecciones cardiovasculares, enfermedades infecciosas y cáncer. Los complejosradiofarmacéuticos comprenden radionúclido de metal de transición, un quelante del metal de transición, un grupo biológicamente activo conectado con dichoquelante, un primer ligante auxiliar, un segundo ligante auxiliar capaz de estabilizar el agente radiofarmacéutico, presentando optativamente un grupode enlace entre dicho quelante y dicho grupo biológicamente activo. Los complejos radiofarmacéuticos preferidos tienen la fórmula:[(Q)d-Ln-Ch]x-Mt(Al1)y(Al2)z, donde las variables tienen los valores que se indican.It provides new radiopharmaceutical complexes and a set of elements (kits) to prepare these complexes. These complexes are useful as imaging agents in the diagnosis of cardiovascular conditions, infectious diseases, and cancer. Radiopharmaceutical complexes comprise transition metal radionuclide, a transition metal chelator, a biologically active group connected to said chelator, a first auxiliary binder, a second auxiliary binder capable of stabilizing the radiopharmaceutical agent, optionally having a linker group between said chelator and said biologically active group. Preferred radiopharmaceutical complexes have the formula: [(Q) d-Ln-Ch] x-Mt (Al1) and (Al2) z, where the variables have the values indicated.

ARP970100975A 1996-03-13 1997-03-12 RADIOPHARMACEUTICAL COMPLEXES AND SET OF ELEMENTS TO PREPARE SUCH COMPLEXES AR006192A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1336096P 1996-03-13 1996-03-13
US64686696A 1996-05-08 1996-05-08

Publications (1)

Publication Number Publication Date
AR006192A1 true AR006192A1 (en) 1999-08-11

Family

ID=26684746

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970100975A AR006192A1 (en) 1996-03-13 1997-03-12 RADIOPHARMACEUTICAL COMPLEXES AND SET OF ELEMENTS TO PREPARE SUCH COMPLEXES

Country Status (2)

Country Link
AR (1) AR006192A1 (en)
HR (1) HRP970139A2 (en)

Also Published As

Publication number Publication date
HRP970139A2 (en) 1998-10-31

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