AR004489A1 - BENZOPYRANS, THEIR USE TO PREPARE MEDICINES, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, THE PROCEDURES FOR PREPARING SUCH INTERMEDIATE COMPOUNDS AND COMPOUNDS - Google Patents

BENZOPYRANS, THEIR USE TO PREPARE MEDICINES, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, THE PROCEDURES FOR PREPARING SUCH INTERMEDIATE COMPOUNDS AND COMPOUNDS

Info

Publication number
AR004489A1
AR004489A1 ARP960102708A AR10270896A AR004489A1 AR 004489 A1 AR004489 A1 AR 004489A1 AR P960102708 A ARP960102708 A AR P960102708A AR 10270896 A AR10270896 A AR 10270896A AR 004489 A1 AR004489 A1 AR 004489A1
Authority
AR
Argentina
Prior art keywords
compounds
benzopyrans
preparing
pharmaceutical compositions
procedures
Prior art date
Application number
ARP960102708A
Other languages
Spanish (es)
Original Assignee
Gosling Christopher David
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10774940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR004489(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gosling Christopher David filed Critical Gosling Christopher David
Publication of AR004489A1 publication Critical patent/AR004489A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen derivados de benzopirano, en particular 2,2-dialquil C1-5 o trans-2,2-dialquil C1-5-3,4-dihidro-3-hidroxi-4-carboxamido-6-(N-arisulfonamido)-2H-1-benzopiranos; sus N-óxidos ésteres y sales; su utilización para preparar medicamentos,la s composiciones farmacéuticas que contienendichos compuestos y el procedimiento para prepararlos. Los compuestos actúan en la apertura del canal de potasio, son broncodilatadores y agentes para lasupresión de la hiperreactividad de las víasaéreas.Benzopyran derivatives are described, in particular 2,2-C1-5 dialkyl or trans-2,2-C1-5-3 dialkyl ,,4-dihydro-3-hydroxy-4-carboxamido-6- (N-arisulfonamido) - 2H-1-benzopyrans; its N-oxide esters and salts; their use to prepare medicaments, the pharmaceutical compositions containing said compounds and the process for preparing them. The compounds act in the opening of the potassium channel, they are bronchodilators and agents for the suppression of the hyperreactivity of the airways.

ARP960102708A 1995-05-24 1996-05-24 BENZOPYRANS, THEIR USE TO PREPARE MEDICINES, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, THE PROCEDURES FOR PREPARING SUCH INTERMEDIATE COMPOUNDS AND COMPOUNDS AR004489A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9510477.4A GB9510477D0 (en) 1995-05-24 1995-05-24 Organic compounds

Publications (1)

Publication Number Publication Date
AR004489A1 true AR004489A1 (en) 1998-12-16

Family

ID=10774940

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960102708A AR004489A1 (en) 1995-05-24 1996-05-24 BENZOPYRANS, THEIR USE TO PREPARE MEDICINES, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, THE PROCEDURES FOR PREPARING SUCH INTERMEDIATE COMPOUNDS AND COMPOUNDS

Country Status (31)

Country Link
US (1) US5905156A (en)
EP (1) EP0828733B1 (en)
JP (1) JPH11505820A (en)
KR (1) KR100437981B1 (en)
CN (1) CN1077888C (en)
AR (1) AR004489A1 (en)
AT (1) ATE205204T1 (en)
AU (1) AU703276B2 (en)
BR (1) BR9609048A (en)
CA (1) CA2217821C (en)
CO (1) CO4700520A1 (en)
CZ (1) CZ294474B6 (en)
DE (1) DE69615019T2 (en)
DK (1) DK0828733T3 (en)
ES (1) ES2163634T3 (en)
FI (1) FI973992A (en)
GB (1) GB9510477D0 (en)
HK (1) HK1014137A1 (en)
HU (1) HU222772B1 (en)
IL (1) IL118382A (en)
MY (1) MY114924A (en)
NO (1) NO314846B1 (en)
NZ (1) NZ309765A (en)
PL (1) PL184144B1 (en)
PT (1) PT828733E (en)
RU (1) RU2160735C2 (en)
SK (1) SK283215B6 (en)
TR (1) TR199701417T1 (en)
TW (1) TW421646B (en)
WO (1) WO1996037490A1 (en)
ZA (1) ZA964209B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972894A (en) * 1997-08-07 1999-10-26 Cytran, Inc. Peptides having potassium channel opener activity
GB9822024D0 (en) * 1998-10-09 1998-12-02 Novartis Ag Organic compounds
GB9909792D0 (en) * 1998-12-04 1999-06-23 Cambridge Bioclinical Limited Potassium channel activators and their use
US6384244B2 (en) 2000-05-18 2002-05-07 Merck & Co., Inc. Process for preparing cis- aminochromanols
US7098340B2 (en) * 2003-05-14 2006-08-29 Warner Lambert Company Llc Benzyl sulfonamide derivatives
KR100704009B1 (en) * 2005-08-30 2007-04-04 한국화학연구원 6-Alkylamino-2-methyl-2'-N-methyl substituted sulfonamidomethyl-2H-1-benzopyran derivatives as anti-inflammatory inhibitors
JP6987746B2 (en) 2015-09-28 2022-01-05 ジェネンテック， インコーポレイテッド Therapeutic compounds and their usage
CN106008288A (en) * 2016-06-15 2016-10-12 西北农林科技大学 Benzsulfamide compound and application thereof
CN110546148A (en) 2017-03-24 2019-12-06 基因泰克公司 4-piperidine-N- (pyrimidin-4-yl) chroman-7-sulfonamide derivatives as sodium channel inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2030627A6 (en) * 1990-11-28 1992-11-01 Uriach & Cia Sa J New benzopyran compounds with pharmacological activity.
KR950009863B1 (en) * 1991-05-22 1995-08-29 재단법인한국화학연구소 Benzopyran derivatives and process for preparing the same
TW244350B (en) * 1991-12-14 1995-04-01 Hoechst Ag
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
BR9609048A (en) 1999-02-23
FI973992A (en) 1997-12-09
RU2160735C2 (en) 2000-12-20
HU222772B1 (en) 2003-10-28
SK157797A3 (en) 1998-05-06
NO314846B1 (en) 2003-06-02
US5905156A (en) 1999-05-18
AU703276B2 (en) 1999-03-25
NO975365L (en) 1998-01-15
NO975365D0 (en) 1997-11-21
TW421646B (en) 2001-02-11
HK1014137A1 (en) 1999-09-24
GB9510477D0 (en) 1995-07-19
JPH11505820A (en) 1999-05-25
CZ294474B6 (en) 2005-01-12
AU6000896A (en) 1996-12-11
EP0828733B1 (en) 2001-09-05
PL184144B1 (en) 2002-09-30
CO4700520A1 (en) 1998-12-29
ES2163634T3 (en) 2002-02-01
MX9709004A (en) 1998-03-31
DE69615019T2 (en) 2002-06-06
PL324042A1 (en) 1998-05-11
KR19990021925A (en) 1999-03-25
IL118382A0 (en) 1996-09-12
ATE205204T1 (en) 2001-09-15
CA2217821A1 (en) 1996-11-28
MY114924A (en) 2003-02-28
DE69615019D1 (en) 2001-10-11
CZ368897A3 (en) 1998-02-18
HUP9801751A3 (en) 1999-08-30
KR100437981B1 (en) 2004-07-16
ZA964209B (en) 1997-11-24
WO1996037490A1 (en) 1996-11-28
CN1185153A (en) 1998-06-17
EP0828733A1 (en) 1998-03-18
SK283215B6 (en) 2003-03-04
DK0828733T3 (en) 2001-12-17
TR199701417T1 (en) 1998-02-21
CN1077888C (en) 2002-01-16
HUP9801751A2 (en) 1999-06-28
NZ309765A (en) 2000-01-28
FI973992A0 (en) 1997-10-17
PT828733E (en) 2002-02-28
IL118382A (en) 2000-01-31
CA2217821C (en) 2008-05-06

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