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Application filed by Merck & Co Inc, Zeneca LtdfiledCriticalMerck & Co Inc
Publication of AR003309A1publicationCriticalpatent/AR003309A1/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
Procedimiento de preparación de un derivado del anillo de tienotiopirano de la fórmula estructural (I), en donde R es hidrógeno, alquil C1-4, o alcoxiC1-4-alquil C1-4, que comprende agregar un anhídrido a una primera solución que contiene unsolvente y un compuesto de fórmula (II), donde R es como sedescribió anteriormente, manteniendo una temperatura desde alrededor de -5 hasta alrededor de 50°C para producir una solución que contenga a un compuestode fórmula estructural (III), endonde R es como se describió anteriormente, agregando a la segunda solución un agente oxidante, manteniendo una temperaturadesde alrededor de 15°C hasta alrededor de 80°C, para producir el compuesto (IV), en donde R es como se describióanteriormente, reduciendo el compuesto(IV) para producir el compuesto (V) y aislando el compuesto (V).Procedure for preparing a thienothiopyran ring derivative of structural formula (I), wherein R is hydrogen, C1-4alkyl, or C1-4alkoxy-C1-4alkyl, which comprises adding an anhydride to a first solution containing A solvent and a compound of formula (II), where R is as previously described, maintaining a temperature from around -5 to around 50 ° C to produce a solution containing a compound of structural formula (III), where R is as described above, adding an oxidizing agent to the second solution, maintaining a temperature from around 15 ° C to around 80 ° C, to produce compound (IV), where R is as previously described, reducing compound (IV) to produce compound (V) and isolating compound (V).
ARP960104050A1995-08-291996-08-20
PROCEDURE FOR THE PREPARATION OF A DERIVATIVE OF THE TIENOTIOPYRAN RING
AR003309A1
(en)
A COMPOUND OF 2-CARBOXINDOL-3-SUBSTITUTED, A PROCESS FOR ITS PREPARATION, A NEW INTERMEDIATE COMPOUND FOR SUCH PROCESS, THE USE OF THE COMPOUND FOR THE MANUFACTURE OF A THERAPEUTIC AGENT AND A PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH A COMPOUND.
DERIVATIVES OF OXAZOLINE, PROCEDURE FOR ITS PREPARATION AND AGRICULTURAL AND HORTICOLE COMPOSITIONS FOR THE CONTROL OF HARMFUL ORGANISMS THAT CONTAIN THEM.