AR001661A1 - A procedure to prepare racemic 1- (r, s) - (2-pyridyl) -2-cyclohexylethylamine a procedure to separate (+) - s-sigma (-) - r-1- (2-pyridyl) -2-cyclohexylethylamine from the racemic mixture procedure to prepare a leukotriene biosynthesis inhibitor using these separate enantiomers and a procedure to prepare (+) - or (-) - 3-bromocampho-8-sulfonic acid used in the separation of the enantiomers - Google Patents
A procedure to prepare racemic 1- (r, s) - (2-pyridyl) -2-cyclohexylethylamine a procedure to separate (+) - s-sigma (-) - r-1- (2-pyridyl) -2-cyclohexylethylamine from the racemic mixture procedure to prepare a leukotriene biosynthesis inhibitor using these separate enantiomers and a procedure to prepare (+) - or (-) - 3-bromocampho-8-sulfonic acid used in the separation of the enantiomersInfo
- Publication number
- AR001661A1 AR001661A1 AR33621796A AR33621796A AR001661A1 AR 001661 A1 AR001661 A1 AR 001661A1 AR 33621796 A AR33621796 A AR 33621796A AR 33621796 A AR33621796 A AR 33621796A AR 001661 A1 AR001661 A1 AR 001661A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- prepare
- cyclohexylethylamine
- pyridyl
- enantiomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyridine Compounds (AREA)
Abstract
Esta invención se refiere a la preparación de 1-(piridil)-2-ciclohexiletilamina racémica y enantiómera y, en particular, a laseparación (+) - (S)- ó (-)-(R)-1-(2-piridil)-2-ciclohexiletilamina a partir de una mezcla racémica de 1-(R,S)-(2-piridil)-2-ciclohexiletilamina. De acuerdocon esta invención, la separación de una mezcla racémica de 1-(piridil)-2- ciclohexiletilamina se lleva a cabo utilizando ácido 3-bromocanfo-8-sulfónico(BCSA). Esta invención se refiere también a un procedimiento para preparar una mezcla racémica de 1-(piridil)-2-ciclohexiletilamina y BCSA libre a partir demateriales de partida fácilmente disponibles.This invention relates to the preparation of racemic and enantiomeric 1- (pyridyl) -2-cyclohexylethylamine and, in particular, to the separation (+) - (S) - or (-) - (R) -1- (2-pyridyl ) -2-cyclohexylethylamine from a racemic mixture of 1- (R, S) - (2-pyridyl) -2-cyclohexylethylamine. According to this invention, the separation of a racemic mixture of 1- (pyridyl) -2-cyclohexylethylamine is carried out using 3-bromocampho-8-sulfonic acid (BCSA). This invention also relates to a process for preparing a racemic mixture of 1- (pyridyl) -2-cyclohexylethylamine and free BCSA from readily available starting materials.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AR33621796A AR001661A1 (en) | 1996-04-19 | 1996-04-19 | A procedure to prepare racemic 1- (r, s) - (2-pyridyl) -2-cyclohexylethylamine a procedure to separate (+) - s-sigma (-) - r-1- (2-pyridyl) -2-cyclohexylethylamine from the racemic mixture procedure to prepare a leukotriene biosynthesis inhibitor using these separate enantiomers and a procedure to prepare (+) - or (-) - 3-bromocampho-8-sulfonic acid used in the separation of the enantiomers |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AR33621796A AR001661A1 (en) | 1996-04-19 | 1996-04-19 | A procedure to prepare racemic 1- (r, s) - (2-pyridyl) -2-cyclohexylethylamine a procedure to separate (+) - s-sigma (-) - r-1- (2-pyridyl) -2-cyclohexylethylamine from the racemic mixture procedure to prepare a leukotriene biosynthesis inhibitor using these separate enantiomers and a procedure to prepare (+) - or (-) - 3-bromocampho-8-sulfonic acid used in the separation of the enantiomers |
Publications (1)
Publication Number | Publication Date |
---|---|
AR001661A1 true AR001661A1 (en) | 1997-11-26 |
Family
ID=37027983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR33621796A Pending AR001661A1 (en) | 1996-04-19 | 1996-04-19 | A procedure to prepare racemic 1- (r, s) - (2-pyridyl) -2-cyclohexylethylamine a procedure to separate (+) - s-sigma (-) - r-1- (2-pyridyl) -2-cyclohexylethylamine from the racemic mixture procedure to prepare a leukotriene biosynthesis inhibitor using these separate enantiomers and a procedure to prepare (+) - or (-) - 3-bromocampho-8-sulfonic acid used in the separation of the enantiomers |
Country Status (1)
Country | Link |
---|---|
AR (1) | AR001661A1 (en) |
-
1996
- 1996-04-19 AR AR33621796A patent/AR001661A1/en active Pending
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