AP2633A - Novel hydroxy functionalized 1,2,4-trioxanes as antimalarial agents and a process for the preparation thereof. - Google Patents

Novel hydroxy functionalized 1,2,4-trioxanes as antimalarial agents and a process for the preparation thereof.

Info

Publication number
AP2633A
AP2633A AP2010005405A AP2010005405A AP2633A AP 2633 A AP2633 A AP 2633A AP 2010005405 A AP2010005405 A AP 2010005405A AP 2010005405 A AP2010005405 A AP 2010005405A AP 2633 A AP2633 A AP 2633A
Authority
AP
ARIPO
Prior art keywords
trioxanes
preparation
antimalarial agents
hydroxy functionalized
novel hydroxy
Prior art date
Application number
AP2010005405A
Other versions
AP2010005405A0 (en
Inventor
Chandan Singh
Ram Prakash Verma
Sunil Kumar Puri
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Publication of AP2010005405A0 publication Critical patent/AP2010005405A0/en
Application granted granted Critical
Publication of AP2633A publication Critical patent/AP2633A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C07D323/04—Six-membered rings
    • C07D323/06—Trioxane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AP2010005405A 2008-03-26 2008-10-31 Novel hydroxy functionalized 1,2,4-trioxanes as antimalarial agents and a process for the preparation thereof. AP2633A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN768DE2008 2008-03-26
PCT/IN2008/000711 WO2009118747A1 (en) 2008-03-26 2008-10-31 Novel hydroxy functionalized 1, 2, 4-trioxanes as antimalarial agents and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
AP2010005405A0 AP2010005405A0 (en) 2010-10-31
AP2633A true AP2633A (en) 2013-04-03

Family

ID=40343534

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2010005405A AP2633A (en) 2008-03-26 2008-10-31 Novel hydroxy functionalized 1,2,4-trioxanes as antimalarial agents and a process for the preparation thereof.

Country Status (3)

Country Link
AP (1) AP2633A (en)
BR (1) BRPI0822467A2 (en)
WO (1) WO2009118747A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082852A1 (en) * 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research Novel substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008099415A1 (en) * 2007-02-13 2008-08-21 Council Of Scientific & Industrial Research Novel substituted bis-1, 2, 4-trioxanes and a process for preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082852A1 (en) * 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research Novel substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SINGH C ET AL: "In vivo potent antimalarial 1,2,4-trioxanes: synthesis and activity of 8-(alpha-arylvinyl)-6,7,10-trioxaspiro[4,5 ]decanes and 3-(alpha-arylvinyl)-1,2,5-trioxaspiro[5,5] undecanes against Plasmodium berghei in mice" BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 5, no. 17, 7 September 1995 (1995-09-07), pages 1913-1916, XP004135334 ISSN: 0960-894X cited in the application *
SINGH C ET AL: "Synthesis of new 6-alkylvinyl/arylalkylvinyl substituted 1,2,4-trioxanes active against multidrug-resistant malaria in mice" BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, vol. 12, no. 21, 1 November 2004 (2004-11-01), pages 5553-5562, XP004588158 ISSN: 0968-0896 *

Also Published As

Publication number Publication date
BRPI0822467A2 (en) 2015-06-16
AP2010005405A0 (en) 2010-10-31
WO2009118747A1 (en) 2009-10-01

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