AP2440A - A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277' - Google Patents

A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277'

Info

Publication number
AP2440A
AP2440A AP2008004703A AP2008004703A AP2440A AP 2440 A AP2440 A AP 2440A AP 2008004703 A AP2008004703 A AP 2008004703A AP 2008004703 A AP2008004703 A AP 2008004703A AP 2440 A AP2440 A AP 2440A
Authority
AP
ARIPO
Prior art keywords
dispiro
preparation
trioxolane antimalarials
trioxolane
antimalarials
Prior art date
Application number
AP2008004703A
Other languages
English (en)
Other versions
AP2008004703A0 (en
Inventor
Gyan Chand Yadav
Harish N Dorwal
Srinivas Valavala
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of AP2008004703A0 publication Critical patent/AP2008004703A0/xx
Application granted granted Critical
Publication of AP2440A publication Critical patent/AP2440A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C07D323/02—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AP2008004703A 2006-05-24 2007-05-24 A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277' AP2440A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1252DE2006 2006-05-24
PCT/IB2007/001374 WO2007138435A2 (en) 2006-05-24 2007-05-24 A process for the preparation of dispiro 1,2,4-trioxolane antimalarials (oz277)

Publications (2)

Publication Number Publication Date
AP2008004703A0 AP2008004703A0 (en) 2008-12-31
AP2440A true AP2440A (en) 2012-08-31

Family

ID=38650060

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004703A AP2440A (en) 2006-05-24 2007-05-24 A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277'

Country Status (14)

Country Link
US (1) US8569519B2 (es)
EP (1) EP2029569B1 (es)
CN (1) CN101490032B (es)
AP (1) AP2440A (es)
BR (1) BRPI0712208A2 (es)
CY (1) CY1113644T1 (es)
DK (1) DK2029569T3 (es)
ES (1) ES2400682T3 (es)
HK (1) HK1137018A1 (es)
PL (1) PL2029569T3 (es)
PT (1) PT2029569E (es)
SI (1) SI2029569T1 (es)
WO (1) WO2007138435A2 (es)
ZA (1) ZA200810218B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102439002B (zh) * 2009-04-17 2015-03-04 兰贝克赛实验室有限公司 1,2,4-三茂烷抗疟药的制备工艺
US11072594B2 (en) 2017-06-27 2021-07-27 The Regents Of The University Of California Trioxolane agents

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486199B1 (en) * 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials
US20040039008A1 (en) * 2002-06-21 2004-02-26 Medicines For Malaria Ventures Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials
US6906205B2 (en) * 2002-06-21 2005-06-14 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486199B1 (en) * 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials
US20040039008A1 (en) * 2002-06-21 2004-02-26 Medicines For Malaria Ventures Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials
US6906205B2 (en) * 2002-06-21 2005-06-14 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JONATHAN L. VENNERSTROM ET AL: "Identification of an antimalarial synthetic trioxolane drug development candidate" NATURE, vol. 430, 19 August 2004 (2004-08-19), pages 900-904, XP002458025 � *

Also Published As

Publication number Publication date
SI2029569T1 (sl) 2013-03-29
EP2029569B1 (en) 2012-12-05
HK1137018A1 (en) 2010-07-16
CN101490032B (zh) 2014-12-17
EP2029569A2 (en) 2009-03-04
PL2029569T3 (pl) 2013-06-28
US8569519B2 (en) 2013-10-29
CY1113644T1 (el) 2016-06-22
US20110124886A1 (en) 2011-05-26
PT2029569E (pt) 2013-02-13
ES2400682T3 (es) 2013-04-11
AP2008004703A0 (en) 2008-12-31
BRPI0712208A2 (pt) 2012-03-13
WO2007138435A3 (en) 2008-02-07
DK2029569T3 (da) 2013-02-11
ZA200810218B (en) 2009-12-30
WO2007138435A2 (en) 2007-12-06
CN101490032A (zh) 2009-07-22

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