WO2019078327A1

WO2019078327A1 - Inflammation evaluation system, evaluation method, program, and non-transient recording medium

Info

Publication number: WO2019078327A1
Application number: PCT/JP2018/038931
Authority: WO
Inventors: 晃久奥谷; 潤一牛場; 幸治森川; 幹生岩川
Original assignee: パナソニック株式会社; 学校法人慶應義塾
Priority date: 2017-10-20
Filing date: 2018-10-19
Publication date: 2019-04-25
Also published as: JP6917600B2; JPWO2019078327A1

Abstract

A problem to be addressed by the present disclosure is to mitigate decreases in evaluation precision. An evaluation system (6) comprises an acquisition part (60) for acquiring a measurement value measured by a measurement device (7) on a skin measurement site (51), the measurement value including an erythema value and an intensity value (melanin value) for a color different from that of the erythema. The evaluation system (6) according to a first aspect comprises an evaluation part (61) for evaluating an inflammation on the basis of the erythema value included in a plurality of measurement values acquired with the acquisition part (60). The evaluation part (61) selects, from among the plurality of measurement values, a measurement value having an intensity value (melanin value) within a prescribed range as an evaluation-candidate measurement value. The evaluation part (61) evaluates the inflammation on the basis of the erythema value included in the evaluation-candidate measurement value.

Description

Evaluation system of inflammation, evaluation method, program, and non-temporary recording medium

The present disclosure relates to an inflammation evaluation system, an evaluation method, a program, and a non-temporary recording medium, and more specifically, an evaluation system, an evaluation method, a program, and a non-temporary for evaluating the degree of inflammation generated in human skin. Recording medium.

One of the inflammations that occur in human skin is erythema. Erythema is a rash name that refers to the redness (redness) of the epidermis caused by capillary dilation or hyperemia of the dermis. Patent Document 1 describes an example of an evaluation method for evaluating the degree of such inflammation (erythema).

The evaluation method described in Patent Document 1 measures the light reflectance of a skin area or a mucous membrane area in which erythema has occurred, and acquires L * value and a * value of the measurement result according to L * a * b * color space. The erythema value is calculated by substituting the obtained value into the equation (L * max−L *) × a *. Furthermore, in the evaluation method described in Patent Document 1, the presence or absence of inflammation and the degree of inflammation are evaluated based on the calculated erythema value.

By the way, when measuring the erythema value, it is necessary to bring the device for measurement into contact with the skin, but the hair present in the epidermis intervenes between the device for measurement and the epidermis, and the erythema value is measured by the influence of the body hair Errors can increase. As the measurement error of the erythema value increases, the accuracy of the evaluation of inflammation also decreases.

JP 2016-518885 gazette

An object of the present disclosure is to provide an inflammation evaluation system, an evaluation method, a program, and a non-temporary recording medium capable of suppressing reduction in accuracy of evaluation.

An inflammation evaluation system according to an aspect of the present disclosure is an evaluation system that evaluates inflammation generated in the skin. The evaluation system acquires an acquisition unit that acquires a measurement value including an intensity value of a color different from the erythema value and the color of the erythema at the measurement site of the skin measured by a measuring instrument, and the plurality of measurements acquired by the acquisition unit And an evaluation unit that evaluates inflammation based on the erythema value included in the value. The evaluation unit compares the erythema value and the intensity value in each of the plurality of measurement values, and compares the erythema value and the intensity value in the comparison with each other, and the measurement value is within a predetermined range as an evaluation candidate Elect to be a measured value. The evaluation unit evaluates inflammation based on the erythema value included in the measurement value of the evaluation candidate.

The evaluation method according to an aspect of the present disclosure is an evaluation method for evaluating inflammation generated in the skin. In the evaluation method, a measurement value including an intensity value of a color different from the color of the erythema and the color of the erythema at the measurement site of the skin measured by a measuring device is obtained, Compare intensity values. In the evaluation method, a measurement value in which the ratio of the erythema value and the intensity value compared is within a predetermined range is selected as the measurement value of the evaluation candidate, and the erythema value included in the measurement value of the evaluation candidate is selected. Assess inflammation based on:

A program according to an aspect of the present disclosure causes a computer system to execute the evaluation method.

The non-temporary recording medium according to an aspect of the present disclosure is a computer system-readable non-temporary recording medium in which a program for causing a computer system to execute a method of evaluating a brain activity measuring device is recorded.

FIG. 1 shows a state of use of an electroencephalogram measurement system including a headset mounted on the head of a subject who is a subject of evaluation of an inflammation evaluation system according to an embodiment of the present disclosure, and a rehabilitation support system including the same. FIG. FIG. 2 is a block diagram showing the configuration of the above-mentioned electroencephalogram measurement system and rehabilitation support system. FIG. 3A is a schematic top view showing the usage state of the above headset. FIG. 3B is a schematic front view showing the usage state of the above headset. FIG. 4 is a system configuration diagram of the above evaluation system. FIG. 5 is a flowchart for explaining the operation of the evaluation system of the same. FIG. 6 is a flowchart for explaining the operation of the evaluation system of the same. FIG. 7 is an explanatory diagram for explaining measurement values in the evaluation system of the same. FIG. 8 is a diagram showing a line graph for explaining the operation of the evaluation system of the same.

Each drawing described in the following embodiments is a schematic drawing, and the size, thickness, and ratio of each component do not necessarily reflect the actual dimensional ratio. The configuration described in the following embodiment is merely an example of the present disclosure. The present disclosure is not limited to the following embodiments, and various modifications can be made according to design etc. as long as the effects of the present disclosure can be obtained.

In describing the evaluation system according to the present embodiment, inflammation to be evaluated in the evaluation system will be described. The inflammation to be evaluated is, for example, inflammation caused by wearing a brain activity measuring apparatus (hereinafter referred to as a headset 1) on the head. The headset 1 constitutes an electroencephalogram measurement system 10 together with an information processing apparatus 2 as shown in FIG.

The electroencephalogram measurement system 10 is a system for measuring the electroencephalogram of the subject 5, and the electroencephalogram from the electrode unit 11 disposed at a position corresponding to the measurement point 51 which is a part of the head 52 of the subject 5 Get information. The term “electroencephalogram (EEG)” as referred to in the present disclosure means a waveform obtained by extruding an electrical signal (action potential) emitted from a cerebral nerve cell (group) and recording it. In the present disclosure, unless otherwise noted, an on-scalp electroencephalogram recorded using the electrode unit 11 attached to the scalp with respect to general action potentials of a large number of neuron groups (neural networks) of the cerebral cortex. It is called "brain wave".

The electroencephalogram measurement system 10 includes a headset 1 (see FIG. 3B) having an electrode unit 11 and an information processing device 2. The headset 1 is mounted on the head 52 of the subject 5 with the electrode unit 11 in contact with the surface (scalp) of the head 52 of the subject 5. In the present disclosure, the electrode unit 11 contacts the surface of the head 52 by being placed on the paste (electrode paste) applied to the surface of the head 52. At this time, the electrode unit 11 contacts the surface of the head 52 without the hair by scraping the hair. Of course, the electrode unit 11 may be in direct contact with the surface of the head 52 without applying a paste. That is, in the present disclosure, “contacting the electrode unit 11 with the surface of the head 52” refers to contacting the electrode unit 11 directly with the surface of the head 52 (including the scalp) or via an intermediate. It also includes bringing the electrode portion 11 into contact with the surface of the head 52 indirectly. The intermediate is not limited to the paste, and may be, for example, a gel having conductivity.

The headset 1 measures the brain waves of the subject 5 by measuring the action potential of the brain of the subject 5 with the electrode unit 11, and generates brain wave information representing the brain waves. The headset 1 transmits brain wave information to the information processing apparatus 2 by wireless communication, for example.

The information processing apparatus 2 mainly includes, for example, a computer system such as a personal computer. The information processing apparatus 2 receives brain wave information from the headset 1 by wireless communication, for example, performs various processes on the brain wave information acquired from the headset 1, and displays the brain wave information. In the present embodiment, detection of an electroencephalogram including characteristic changes that occur when the subject 5 performs a voluntary movement (that is, can occur when the subject 5 intends to perform a voluntary exercise), and The calibration process and the like are performed by the information processing apparatus 2. The “calibration process” in the present disclosure is a process for analyzing brain wave information, that is, for determining various parameters used for detection of a brain wave to be detected.

Next, the headset 1 will be described with reference to FIGS. 1, 3A and 3B. Note that the arrows of “D1” and “D2” shown in the drawings are only shown for the sake of explanation, and do not have an entity.

The headset 1 includes a frame 17, an attachment portion 19, and a pair of holding portions 18. The frame 17 is attachable to the head 52 of the subject 5 and is attached to the head 52 in a first direction from the central portion (vertex) of the subject 5 to the left and right tragus It has a shape extending to D1. In the present disclosure, the “center-center portion” is a position represented by an electrode symbol “Cz” in the international 10-20 method, and in the head 52 of the subject 5, the nose of the subject 5 and the occipital nodule And the line connecting the front end point of the left ear 521 and the front end point of the right ear 522 are crossing points. Further, in the “first direction” in the present disclosure, the central central portion of the subject 5, the left tragus and the right tragus are connected along the head 52 in a state in which the frame 17 is attached to the head 52. It is a direction parallel to the curve.

The attachment portion 19 is provided on the frame 17 and can accommodate the electrode portion 11 used to collect brain waves of the subject 5. The electrode unit 11 contacts a position corresponding to the measurement point 51 on the surface of the head 52 in a state where the frame 17 is attached to the head 52. The frame 17 is provided with a pair of attachment portions 19.

The pair of holding portions 18 is connected to both ends of the frame 17 in the first direction D1, and contacts the head 52 in a state where the frame 17 is mounted on the head 52. In other words, the holding portions 18 are provided at both ends of the frame 17 in the first direction D1. And these holding | maintenance parts 18 hold | maintain the flame | frame 17 with respect to the head 52 by contacting the head 52 in the state with which the flame | frame 17 was mounted | worn with the head 52. As shown in FIG.

The above-described electroencephalogram measurement system 10 is used, for example, in a rehabilitation support system 100 shown in FIG.

The rehabilitation support system 100 is a system for supporting the rehabilitation of the subject 5 using the electroencephalogram measurement system 10 including the headset 1. The rehabilitation support system 100 supports rehabilitation by means of exercise therapy, with a person who has exercise paralysis or a decline in motor function or the like in a part of the body as a subject 5, for example, by a brain disease such as a stroke or an accident. In such a subject 5, a voluntary exercise which is a movement performed by the subject 5 based on the intention or intention of the subject 5 may not be satisfied due to the inability or the deterioration of its function. The “exercise therapy” referred to in the present disclosure is a disorder caused by exercising the inability part of such a voluntary exercise or a part where a decrease in function has occurred (hereinafter referred to as “disability site”) in the body of the subject 5 It means a method to restore the function of voluntary movement for the part.

As shown in FIGS. 1 and 2, the rehabilitation support system 100 includes an electroencephalogram measurement system 10 (including a headset 1), an exercise assistance device 3, and a control device 4.

The exercise assisting device 3 is a device that assists the exercise of the subject 5 by adding at least one of a mechanical stimulation and an electrical stimulation to the subject 5. Since the rehabilitation support system 100 is used for rehabilitation of the left finger of the subject 5, the exercise assisting apparatus 3 is mounted on the left hand of the subject 5 as shown in FIG. 1.

The rehabilitation support system 100 described below is used for the rehabilitation of the grasping motion and the extension motion by the left finger of the subject 5. The “gripping operation” in the present disclosure means an operation of holding an object. In addition, the “extension operation” in the present disclosure is grasped by an operation of opening the hand by the extension of four fingers 53 (second to fifth fingers) other than the first finger (thumb), that is, by the holding operation. It means the action of releasing the "object" of the state. That is, in the subject 5, the left finger is the injury site, and the rehabilitation support system 100 is used for the rehabilitation of the voluntary movement of the grasping motion and the extension motion by the left finger. However, in reality, the rehabilitation support system 100 indirectly assists in the rehabilitation of the grasping motion by assisting the extension motion of the finger of the subject 5, instead of directly assisting the grasping motion of the subject 5. Do.

Therefore, in the rehabilitation support system 100, when the subject 5 tries to perform the extension motion as a voluntary exercise, the exercise assisting device 3 attached to the left hand of the subject 5 mechanically contacts the left finger 53 of the subject 5 And / or electrical stimulation to assist voluntary exercise. That is, the rehabilitation support system 100 assists the voluntary movement (extension movement) when releasing the peg 101 by the extension movement of the finger 53 from the posture in which the subject 5 holds the peg 101 (see FIG. 1) with the left finger. . However, the present invention is not limited to this example, and the rehabilitation support system 100 may be used, for example, for rehabilitation of the right finger of the subject 5.

The exercise assistance device 3 has a finger drive device 31 and an electrical stimulation generator 32 as shown in FIG.

The finger driving device 31 holds four fingers 53 (second to fifth fingers) except the first finger (thumb) and applies mechanical stimulation (external force) to the four fingers 53. , Is a device to move the four fingers 53. The finger driving device 31 includes, for example, a power source such as a motor or a solenoid, and moves the four fingers 53 by transmitting the force generated by the power source to the four fingers 53. The finger drive device 31 moves the held four fingers 53 in a direction away from the first finger (i.e., extending movement) and moves the finger 53 in a direction approaching the first finger (i.e., gripping movement). Two types of operations are possible: a closing operation. The opening operation of the finger driving device 31 assists the extension operation of the subject 5, and the closing operation of the finger driving device 31 assists the gripping operation of the subject 5.

The electrical stimulation generator 32 is a device that applies an electrical stimulation to a site for moving the finger 53 of the subject 5. Here, the site for moving the finger 53 of the subject 5 includes a site corresponding to at least one of the muscle and the nerve of the finger 53 of the subject 5. For example, the part for moving the finger 53 of the subject 5 is a part of the arm of the subject 5. The electrical stimulation generator 32 includes, for example, a pad attached to the body (for example, an arm) of the subject 5. The electrical stimulation generator 32 stimulates a site for moving the finger 53 by applying electrical stimulation (electric current) to the body of the subject 5 from the pad.

The control device 4 controls the exercise assistance device 3 based on the electroencephalogram information acquired by the electroencephalogram measurement system 10. In other words, the control device 4 controls the exercise assistance device 3 in accordance with the brain waves of the subject 5 collected by the electrode unit 11 of the headset 1. The control device 4 is electrically connected to the information processing device 2 of the electroencephalogram measurement system 10 and the exercise assisting device 3. The control device 4 is connected to a power cable for supplying operation power for the exercise assisting device 3 and the control device 4. The control device 4 includes a drive circuit for driving the finger drive device 31 of the exercise assisting device 3 and an oscillation circuit for driving the electrical stimulation generator 32. The control device 4 receives a control signal from the information processing device 2 by, for example, wired communication.

When the control device 4 receives the first control signal from the information processing device 2, the drive circuit drives the finger drive device 31 of the exercise assisting device 3 and the finger drive device 31 performs an “open operation”. Control the exercise assisting device 3; Further, when the control device 4 receives the second control signal from the information processing device 2, the drive circuit drives the finger drive device 31 of the exercise assisting device 3 and the finger drive device 31 performs the “closing operation”. Control the exercise assistance device 3 to be controlled. In addition, when the control device 4 receives the third control signal from the information processing device 2, the control device 4 drives the electric stimulation generator 32 of the exercise assisting device 3 by the oscillation circuit, and the body of the subject 5 is electrically stimulated. The exercise assist device 3 is controlled to be given.

As described above, the control device 4 controls the exercise assistance device 3 based on the control signal output from the electroencephalogram measurement system 10 to thereby provide the exercise assistance device based on the electroencephalogram information acquired by the electroencephalogram measurement system 10. It is possible to control three. In addition, the control device 4 controls the exercise assisting device 3 so that the “opening operation” and the “closing operation” are performed by the finger drive device 31 according to the operation of the operation switch provided in the control device 4 You can also.

For example, as in the case where a medical staff such as a physical therapist or an occupational therapist holds the finger 53 of the subject 5 to assist the voluntary exercise of the subject 5, the rehabilitation support system 100 assists the voluntary exercise It will be possible. Therefore, according to the rehabilitation support system 100, as in the case where the medical staff assists, rehabilitation by exercise therapy can be realized more effectively than when the subject 5 performs voluntary exercise alone.

By the way, in order to support the above-mentioned rehabilitation, the rehabilitation support system 100 can support the voluntary exercise of the subject 5 with the exercise assisting device 3 when the subject 5 tries to do voluntary exercise. desirable. The rehabilitation support system 100 is an exercise assisting device 3 adapted to the voluntary exercise of the subject 5 by linking the exercise assisting device 3 to the brain wave (brain wave information) of the subject 5 measured by the electroencephalogram measurement system 10. Realize the support of voluntary exercise of In other words, the rehabilitation support system 100 uses a brain-machine interface (BMI) technology to operate a machine (exercise assistance device 3) using brain activity (brain waves) to exercise Realize rehabilitation by therapy.

When the subject 5 performs a voluntary exercise (that is, in the process of the subject 5 performing a voluntary exercise), characteristic changes in the electroencephalogram may occur. That is, when the subject 5 intends to perform voluntary exercise, activation of a brain region corresponding to a site targeted for voluntary exercise may occur. An example of such a brain region is the somatosensory motor cortex. A more effective rehabilitation can be expected if the exercise assist device 3 assists the voluntary exercise of the subject 5 according to the timing at which such activation of the brain region occurs. Such activation of the brain region can be detected as a characteristic change of the electroencephalogram. Therefore, the rehabilitation support system 100 executes the assistance of the voluntary exercise of the subject 5 with the exercise assistance device 3 in accordance with the timing at which this characteristic change occurs. Such characteristic changes may occur when the subject 5 images a voluntary exercise (that is, during an exercise attempt) even if the voluntary exercise is not actually performed. That is, such characteristic changes of the electroencephalogram can be activated if the corresponding brain region is activated by the intention of the subject 5 to perform the voluntary exercise, even though the voluntary movement is not actually performed. It can occur. Therefore, even for the subject 5 in a state in which voluntary exercise is impossible, the rehabilitation support system 100 can support voluntary exercise.

The electroencephalogram measurement system 10 detects, as a characteristic change, an intensity change of a specific frequency band that occurs in an electroencephalogram due to occurrence of event-related desynchronization (ERD). The “event-related desynchronization” in the present disclosure means a phenomenon in which the power of a specific frequency band decreases in an electroencephalogram measured in the vicinity of the motor area during voluntary exercise (including recall of voluntary exercise). In the present disclosure, “at the time of voluntary exercise” means a process from the intention of the subject 5 to voluntary exercise (recollection) to the success or failure of the voluntary exercise. The "event-related desynchronization" can occur at the time of this voluntary movement, triggered by the intention (recollection) of the voluntary movement. Frequency bands in which the power decreases due to event-related desynchronization are mainly α waves (for example, a frequency band of 8 Hz to less than 13 Hz) and β waves (for example, a frequency band of 13 Hz to less than 30 Hz).

According to the rehabilitation support system 100 having such a configuration, it is possible to realize effective rehabilitation by exercise therapy in the target person 5 while reducing the burden on the medical staff. Moreover, according to the rehabilitation support system 100, for example, there is no variation in the timing of assisting voluntary exercise due to human factors such as the skill of the medical staff who assists the voluntary exercise of the subject 5, and the variation of the effect of rehabilitation Is reduced. In particular, in the rehabilitation support system 100, the voluntary movement of the subject 5 can be assisted at the timing at which the characteristic change in the electroencephalogram (that is, the timing at which the brain region was actually activated). As described above, in the rehabilitation support system 100, since training can be performed according to the timing of brain activity, contribution to learning and establishment of correct brain activity can be expected. In particular, it is difficult for the subject 5 and the medical staff alone to determine whether or not a characteristic change has occurred in the electroencephalogram. Therefore, by using the rehabilitation support system 100, effective rehabilitation that is difficult to realize only by the target person 5 or the medical staff is possible.

The headset 1 includes a main body 15, a frame 17, and an electrode portion 11, as shown in FIGS. 3A and 3B. The main body 15 is in the form of a box, and includes the signal processing unit 12, the communication unit 13, and the battery 14 inside (see FIG. 2). The headset 1 is battery-powered, and power for operation of the signal processing unit 12 and the communication unit 13 is supplied from the battery 14.

The electrode unit 11 is an electrode for collecting the brain wave (brain wave signal) of the subject 5 and is, for example, a silver-silver chloride electrode. The electrode unit 11 may be silver, gold, platinum or the like. The electrode unit 11 has a first electrode 111 and a second electrode 112. As shown in FIG. 3B, the measurement point 51 set on the surface of the head 52 of the subject 5 includes a first measurement point 511 and a second measurement point 512. The first electrode 111 is an electrode corresponding to the first measurement point 511, and is disposed on the first measurement point 511. The second electrode 112 is an electrode corresponding to the second measurement point 512, and is disposed on the second measurement point 512. Specifically, the first measurement point 511 and the second measurement point 512 are located on the line connecting the center of the center of the head 52 and the point at which the front part of the right ear 522 is located. The measurement points 511 and the second measurement points 512 are arranged in order.

When the subject 5 intends to perform a voluntary exercise (remembering), an electroencephalogram including a characteristic change is usually generated in an exercise area corresponding to a site where the voluntary exercise of the body is to be performed. Therefore, the electroencephalogram measurement system 10 measures an electroencephalogram collected from the vicinity of the motor area corresponding to the injury site that is the target of rehabilitation. Here, the motor area corresponding to the left finger is in the right brain of the subject 5, and the motor area corresponding to the right finger is in the left brain of the subject 5. Therefore, when making the left finger 53 of the subject 5 into the object of rehabilitation, it acquires in the electrode part 11 (the 1st electrode 111 and the 2nd electrode 112) made to contact the right side of the head 52 of the subject 5 The electroencephalogram that is generated is the measurement target in the electroencephalogram measurement system 10. That is, the electrode part 11 (the 1st electrode 111 and the 2nd electrode 112) is arrange | positioned on the measurement location 51 which consists of a part of right side surface of the head 52 of the subject 5 as shown to FIG. 3B. As an example, the electrode portion 11 (the first electrode 111 and the second electrode 112) is disposed at a position represented by the electrode symbol "C4" in the international 10-20 method. When the right finger of the subject 5 is targeted for rehabilitation, the measurement site consisting of a part of the left surface of the head 52 of the subject 5, for example, the electrode symbol "C3" in the international 10-20 method The electrode portion 11 (the first electrode 111 and the second electrode 112) is disposed at the position to be displayed.

The headset 1 further includes a reference electrode 113 and a ground electrode 114. The reference electrode 113 is an electrode for measuring a reference potential of an electroencephalogram signal measured by each of the first electrode 111 and the second electrode 112. The reference electrode 113 is disposed at a rear position of either the left ear 521 or the right ear 522 in the head 52. Specifically, the reference electrode 113 is disposed at the head 52 at a position behind the ear on which the first electrode 111 and the second electrode 112 are disposed. In the illustrated example, since the first electrode 111 and the second electrode 112 are disposed on the right surface of the head 52, the reference electrode 113 is disposed at the rear position of the right ear 522. The ground electrode 114 is disposed at the rear of the left ear 521 or the right ear 522 of the head 52 where the reference electrode 113 is not disposed. Since the reference electrode 113 is disposed at the rear position of the right ear 522, the ground electrode 114 is disposed at the rear position of the left ear 521. Each of the reference electrode 113 and the ground electrode 114 is electrically connected to the main body 15 of the headset 1 by the electric wire 16, and is attached to the surface (scalp) of the head 52. The position where the reference electrode 113 and the ground electrode 114 are disposed may be the earlobe instead of the position behind the ear as described above. The posterior position of the ear and the earlobe are places in the head that are less susceptible to biopotentials from brain activity. That is, it is preferable that the reference electrode 113 and the ground electrode 114 be disposed at a position on the head that is not easily influenced by bioelectric potential derived from brain activity.

The signal processing unit 12 is electrically connected to the electrode unit 11, and performs signal processing on an electroencephalogram signal (electric signal) input from the electrode unit 11 to generate electroencephalogram information. The electroencephalogram signal includes a voltage signal which is a potential difference between the potential of the first electrode 111 and a potential of the reference electrode 113, and a voltage signal which is a potential difference between the potential of the second electrode 112 and a potential of the reference electrode 113. . That is, the headset 1 measures the brain waves of the subject 5 by measuring the action potential of the brain of the subject 5 by the electrode unit 11, and generates the brain wave information representing the brain waves by the signal processing unit 12. The signal processing unit 12 includes at least an amplifier for amplifying an electroencephalogram signal and an A / D converter for A / D conversion, and outputs an electroencephalogram signal in digital form after amplification as electroencephalogram information.

The communication unit 13 has a communication function with the information processing device 2. The communication unit 13 transmits at least the electroencephalogram information generated by the signal processing unit 12 to the information processing device 2. In the present embodiment, the communication unit 13 can communicate bi-directionally with the information processing apparatus 2. The communication method of the communication unit 13 is, for example, wireless communication conforming to Bluetooth (registered trademark) or the like. From the communication unit 13, electroencephalogram information is transmitted to the information processing device 2 as needed.

The frame 17 is horseshoe-like (in other words, in the form of an Alice band). That is, the frame 17 has a shape extending in the first direction D1 from the center portion toward the left tragus and the right tragus in a state where the frame 17 is mounted on the head 52. The frame 17 is configured of a strip-shaped metal plate long in the first direction, and a resin cover that covers at least a part of the metal plate. The frame 17 is flexible. Therefore, by bending the frame 17, it is possible to widen the distance between both ends of the frame 17 in the first direction D1. Therefore, when attaching the frame 17 to the head 52, the head 52 is inserted between both ends of the frame 17 in the first direction D1 by appropriately bending the frame 17 according to the size of the head 52. Is possible.

A main body 15 is attached to a central portion of the frame 17 in the first direction D1. Here, as shown in FIG. 3A, when the frame 17 is mounted on the head 52, the main body 15 is an opening for confirming whether the main body 15 is disposed at an appropriate position with respect to the central portion in the center. The part 151 is provided. The opening 151 penetrates the main body 15 in a direction intersecting (orthogonal to) both the first direction D1 and the second direction D2. For example, when the medical staff mounts the headset 1 on the head 52 of the subject 5, the main body 15 is disposed at a position where the central portion of the head 52 can be seen through the opening 151 of the main body 15. , The mounting position of the headset 1 can be adjusted.

Holding portions 18 are connected to both ends of the frame 17 in the first direction D1. In other words, in the state where the frame 17 is attached to the head 52, the holding portion 18 is connected to one end on the left tragus side of the frame 17 and one end on the right tragus side. The holding unit 18 is configured to be movable along the first direction D1 with respect to the frame 17. That is, the distance between the holding portion 18 and one end of the frame 17 in the first direction D1 is adjustable.

The holding portion 18 has a base portion 18A and a pad 18B as shown in FIG. 3B. The base 18A and the pad 18B are both curved along the head 52 when the frame 17 is attached to the head 52.

The base 18A is in the form of a flat rectangular parallelepiped elongated in the second direction D2, and is connected to the frame 17. One end of the base 18A in the second direction D2 (here, one end on the occipital node side of the head 52) has a dimension in the first direction D1 larger than that of the other portion of the base 18A. The surface fastener is provided in the part which opposes the head 52 among the base 18A.

The pad 18B has a flat rectangular parallelepiped shape that is long in the second direction D2, and is attached to the base 18A. The pad 18B is located between the base 18A and the head 52 and in contact with the head 52 with the frame 17 mounted on the head 52. The pad 18B is made of, for example, a urethane resin, and has a hardness lower than that of the base 18A. Therefore, the pad 18B comes into contact with the head 52 when the frame 17 is attached to the head 52, so that the pad 18B sandwiched between the headset 1 and the head 52 is deformed, and the head from the headset 1 is Reduce the force on 52.

A surface fastener is attached to a part of the pad 18B facing the base 18A. And the pad 18B is attached to the base 18A by bonding the surface fastener of the pad 18B to the surface fastener of the base 18A. Thus, the pad 18B is removable from the base 18A.

The pair of hooking portions 184 are provided at both ends of the holding portion 18 in the second direction D2. The hooking portion 184 is formed in a hook shape, and one end of the band is configured to be hooked. The band has a long shape along the circumferential direction (second direction D2) of the head 52 and has elasticity. The band is attached to the head 52 by hooking both ends thereof to hooks 184 on the forehead side and / or the occipital side of the pair of holding portions 18, respectively. By mounting the band, the headset 1 is firmly fixed by the head 52. For this reason, it can suppress that position shift of the headset 1 arises by the change of the attitude | position of the subject person 5, etc. FIG.

The frame 17 is further provided with a pair of attachment portions 19. The pair of attachment portions 19 are provided on both sides of the main body 15 in the first direction D1. At least one of the pair of attachment portions 19 has a first electrode 111 and a second electrode 112. In the present embodiment, the mounting portion 19 on the right ear 522 side of the subject 5 among the pair of mounting portions 19 has the first electrode 111 and the second electrode 112.

The mounting portion 19 has a base 190, a first case 191, a second case 192, and a handle 193. The base 190 has a shape that sandwiches the frame 17 in the second direction D2. The base 190 is configured to be movable in the first direction D1 along the frame 17. Therefore, by adjusting the position of the base 190 with respect to the frame 17 in the first direction D1, it is possible to adjust the position of the electrode portion 11 (the first electrode 111 and the second electrode 112) as a result.

The handle 193 is provided on the base 190. The handle 193 is used to selectively switch between a state in which the base 190 is fixed relative to the frame 17 and a state in which the base 190 is movable relative to the frame 17. Specifically, by tightening the handle 193, the base 190 is fixed to the frame 17. By loosening the handle 193, the base 190 can be moved relative to the frame 17.

Each of the first case 191 and the second case 192 is a cylindrical body having an elliptical bottom. The first case 191 has a first bottom (a bottom facing the head 52) attached to the base 190, and the first electrode 111 and the second electrode 112 are held therein. Each of the first electrode 111 and the second electrode 112 has a first end (one end facing the head 52) protruding from the first case 191. The first electrode 111 and the second electrode 112 are both configured to be movable relative to the first case 191 so that the amount of protrusion from the first case 191 can be changed. A coil spring is accommodated in the first case 191. The coil spring is disposed between the second ends of the first electrode 111 and the second electrode 112 and the second bottom of the first case 191 (the bottom opposite to the first bottom). One end of the coil spring is fixed to the bottom of the first case 191.

The second case 192 has an open first end (one end facing the head 52), and the outer shape when viewed in the normal direction of the surface (scalp) of the head 52 is larger than that of the first case 191 . The second case 192 is combined with the first case 191 so as to store a part of the first case 191 inside through the opening. The second case 192 is configured to be movable relative to the first case 191 between the first position and the second position in the direction in which the coil spring expands and contracts. In the first position, the amount of projection of the first case 191 from the second case 192 is the smallest, and in the second position, the amount of projection of the first case 191 from the second case 192 is the largest. The first end of the shaft passing through the second bottom of the first case 191 is fixed to the inner bottom of the second end of the second case 192 (the end opposite to the first end). The second end of the shaft is fixed to the first electrode 111 and the second electrode 112. Therefore, by moving the second case 192 between the first position and the second position with respect to the first case 191, the first electrode 111 and the second electrode 112 are moved along with the movement of the second case 192 and the shaft. Move too. That is, by moving the second case 192 with respect to the first case 191, it is possible to adjust the amount of projection of the first electrode 111 and the second electrode 112 from the first case 191.

Furthermore, the second case 192 is configured to be movable in the second direction D2 with respect to the first case 191 at the second position. Then, the first end of the second case 192 is hooked on the second bottom of the first case 191 by moving the second case 192 in the second direction D2 at the second position. Here, when the second case 192 is moved from the first position to the second position by pulling the second case 192, the first electrode 111 and the second electrode 112 move to the inside of the first case 191. The coil spring is compressed. Then, when the pulling force of the second case 192 is released, the first electrode 111 and the second electrode 112 return to the original state by the elastic force of the coil spring. On the other hand, when the second case 192 is hooked to the first case 191 as described above, the movement of the second case 192 from the second position to the first position is restricted, so the compressed state of the coil spring is maintained. be able to. That is, in this case, the state in which the first electrode 111 and the second electrode 112 move to the inside of the first case 191 can be maintained.

When the headset 1 is attached to the head 52 of the subject 5, each of the first electrode 111 and the second electrode 112 is pushed by the head 52 and maintained in the state of being moved to the inside of the first case 191. Ru. That is, each of the first electrode 111 and the second electrode 112 pushes the measurement point 51 of the head 52 by the elastic force of the compressed coil spring. When measuring the brain waves of the subject 5 with the headset 1, it is desirable that the first electrode 111 and the second electrode 112 be in close contact with the measurement location 51 of the head 52. Therefore, in the headset 1, the adhesion between the first electrode 111 and the second electrode 112 and the measurement point 51 is enhanced by pressing the first electrode 111 and the second electrode 112 against the measurement point 51 by the elastic force of the coil spring. ing. Here, as the time when the first electrode 111 and the second electrode 112 are pressed against the measurement point 51 becomes longer, erythema tends to occur at the measurement point 51 where the first electrode 111 and the second electrode 112 are pressed. Become. Then, when erythema occurs in the measurement point 51, it is necessary to determine (evaluate) whether the erythema is persistent erythema or temporary erythema. It is considered that persistent erythema is caused by leakage of red blood cells due to the rupture of blood vessels and is likely to be wrinkled over time. Acupuncture and moxibustion are irreversibly obstructive, and often appear as erythema at the early stage of development. On the other hand, temporary erythema is reactive hyperemia due to the dilation of microvessels in the deep dermis and is not wrinkles.

In general, there is a finger pressing method as a method of easily identifying persistent erythema and temporary erythema. In the finger pressing method, the examiner presses the erythema portion with a finger for 3 seconds to determine whether the erythema portion changes whitish or not. When the erythema part becomes white, it can be determined that it is a reversible skin condition (reactive hyperemia) and not a wrinkle, and when it does not disappear white, it can be determined as a persistent erythema due to persistent erythema.

However, in the finger pressing method as described above, there is a problem that the variation in the determination result due to the individual difference of the examiner is large. Therefore, it is preferable to measure the erythema value of the measurement point 51 by the method described in the prior art, and to determine whether the erythema is a persistent erythema or a temporary erythema based on the erythema value. However, in the case where hair grows at the measurement point 51 where erythema occurs due to the wearing of the headset 1 described above, it is difficult to convince the object person 5 to shave the hair although it is for rehabilitation. On the other hand, if it is attempted to measure the erythema value of the scalp under the hair without shaving the hair, the measurement accuracy of the erythema value may be significantly reduced due to the influence of the hair. Therefore, in assessing the inflammation (erythema) occurring at the measurement site 51 of the subject 5, it is desirable to reduce the influence of the hair on the measurement value (erythema value) as much as possible without shaving the hair.

Next, an inflammation evaluation system (hereinafter referred to as an evaluation system) 6 according to the present embodiment will be described. As shown in FIG. 4, the evaluation system 6 uses the measured values (erythema value and melanin value) measured by the measuring device 7 to evaluate the inflammation of the affected area.

The measuring instrument 7 used in the evaluation system 6 of the present embodiment includes a probe 70, an LED drive circuit 71, a light receiving circuit 72, a control circuit 73, and a transmission circuit 74.

The probe 70 has a cylindrical probe body 700 having a cavity inside. A circular opening 7000 is provided at the bottom of the probe body 700. A plurality of (for example, 16) LEDs 702 and light receiving units 703 are accommodated in the internal space of the probe main body 700.

The plurality of LEDs 702 include a plurality of types of LEDs whose emission light wavelengths are different from each other, for example, an LED that emits green light with a wavelength of 568 nm, an LED that emits red light with a wavelength of 660 nm, and an infrared light with a wavelength of 880 nm And an LED that emits light. The plurality of LEDs 702 including these three types of LEDs are disposed on one surface (the lower surface in FIG. 4) of the light shielding plate 701 provided in the probe main body 700.

The light shielding plate 701 is formed in a disk shape having a circular through hole 7010 at the center. The light shielding plate 701 is disposed in the probe main body 700 so that the through hole 7010 faces the opening 7000 of the probe main body 700.

The light receiving unit 703 is, for example, a photoelectric conversion element in which a photodiode chip is accommodated in a can with a glass lens. However, the light receiving portion 703 is not limited to a photoelectric conversion element having a photodiode chip, and may be a photoelectric conversion element having a phototransistor or the like. The light receiving unit 703 is accommodated in the probe main body 700 such that the optical axis intersects the center of the opening 7000 of the probe main body 700 through the center of the through hole 7010 of the light shielding plate 701.

The LED drive circuit 71 is configured to be able to supply a drive current to emit light for each of the LEDs 702 of the same type whose emitted light has the same wavelength among the plurality of LEDs 702. For example, the LED drive circuit 71 includes a constant current circuit and an analog switch. The analog switch turns on and off the electrical connection between the LED 702 of the same type and the constant current circuit. The constant current circuit supplies a constant current to the plurality of LEDs 702 electrically connected through the analog switch. Note that turning on / off of the analog switch is controlled by the control circuit 73.

The light receiving circuit 72 applies a constant voltage in the forward direction to the light receiving unit 703, and measures the magnitude of the forward current flowing through the light receiving unit 703. Further, the light receiving circuit 72 outputs, to the control circuit 73, a measurement signal having a voltage value corresponding to the magnitude of the forward current (the amount of light received by the light receiving unit 703).

The control circuit 73 is configured of, for example, a microcontroller. The control circuit 73 controls the LED drive circuit 71 to turn on and off the analog switch, and causes the LED drive circuit 71 to drive the plurality of LEDs 702 that emit light of the same wavelength among the plurality of LEDs 702. And transmitting a control signal to instruct. Further, the control circuit 73 AD converts and takes in the measurement signal output from the light receiving circuit 72, obtains the light intensity for each wavelength from data (measurement data) of the digitized measurement signal, and incorporates the obtained light intensity. Store in memory. Furthermore, the control circuit 73 measures the erythema value (hemoglobin concentration) using the light intensity of the green light and the light intensity of the red light of the three types of light (green light, red light, infrared light), The melanin value (melanin pigment concentration) is measured using the light intensity of light and the light intensity of infrared light. However, the control circuit 73 can measure the erythema value and the melanin value at once in a measurement process of about 1 second per time. That is, in the present embodiment, the melanin level (melanin pigment concentration) corresponds to the intensity value.

The transmission circuit 74 has, for example, a general-purpose serial communication interface such as RS-232C. The transmission circuit 74 transmits data of the measurement value including the erythema value and the melanin value measured by the control circuit 73 to the evaluation system 6 through the transmission line. The transmission circuit 74 can also receive data such as a control command from the evaluation system 6 via a transmission line. However, the transmission circuit 74 may have, for example, a serial communication interface other than RS-232C such as RS-485 and USB (Universal Serial Bus), or may have a parallel communication interface.

Specific examples of the measuring device 7 as described above include a skin melanin pigment / hemoglobin measuring device (Mourameter MX18 manufactured by Courage + Khazaka electronic GmbH). If this skin melanin pigment / hemoglobin measuring device is used as the measuring device 7, it is possible to measure the erythema value and the melanin value of the measurement point 51 of the subject 5 in a short time. However, the measuring device 7 is not limited to the above-mentioned skin melanin pigment / hemoglobin measuring device.

The evaluation system 6 of the present embodiment includes an acquisition unit 60 and an evaluation unit 61 as shown in FIG. The evaluation system 6 preferably further includes a storage unit 62 and a notification unit 63.

The acquisition unit 60 performs data transmission with the transmission circuit 74 of the measurement instrument 7 via the transmission line, thereby acquiring a measurement value from the measurement instrument 7. That is, the acquisition unit 60 has the same communication interface as the communication interface of the transmission circuit 74 of the measuring instrument 7.

The evaluation unit 61 selects a measurement value that satisfies a predetermined condition from among a plurality of measurement values acquired by the acquisition unit 60 as a measurement value of an evaluation candidate. Furthermore, the evaluation unit 61 evaluates inflammation (erythema) of the affected area (the measurement point 51 of the head 52 of the subject 5) based on the measurement values of one or more evaluation candidates.

The storage unit 62 is preferably configured by an electrically rewritable non-volatile semiconductor memory such as a flash memory. The notification unit 63 preferably includes a liquid crystal display and a drive circuit that drives the liquid crystal display. The notification unit 63 notifies the evaluator of the evaluation result by causing a liquid crystal display to display a message or a symbol representing the evaluation result of the evaluation unit 61. However, the notification unit 63 may have an acoustic device such as a buzzer or a speaker, and may notify the evaluation result by a sound (such as a buzzer or a voice message).

Here, the acquisition unit 60, the evaluation unit 61, and the storage unit 62 may be configured as semiconductor components in which a computer system is integrated in one semiconductor chip like a microcontroller. Alternatively, the acquisition unit 60, the evaluation unit 61, and the storage unit 62 may be configured by independent electronic circuits. In any of the configurations, the evaluation unit 61 has hardware including a microprocessor and software including a program executed by the microprocessor.

Next, the operation of the evaluation system 6 of the present embodiment (the evaluation method of the present embodiment) will be described. The evaluation of the inflammation by the evaluation system 6 of the present embodiment is performed on the measurement point 51 of the head 52 of the subject 5 who has performed the rehabilitation by the rehabilitation support system 100 described above.

First, the evaluation unit 61 of the evaluation system 6 initializes (the variable of) the number of measurements n to 1 (step S1 in the flowchart of FIG. 5). The operator operating the evaluation system 6 brings the probe 70 of the measuring instrument 7 into contact with the measurement point 51 of the subject 5 to measure the erythema value and the melanin value. However, it is desirable for the operator to perform measurement while removing the hair with a finger so that the hair of the measurement point 51 is not caught as much as possible between the probe 70 and the scalp. In addition, it is preferable that the operator contact the probe 70 at a measurement point 51 where the operator judges with eyes to judge that the erythema value will be the highest and make measurement. Here, the operator once separates the probe 70 from the measurement location 51 of the subject 5 every time one measurement operation is completed, then contact the measurement location 51 again to start the next measurement operation, and the erythema value And the melanin level is measured a predetermined number of times (7 times in this embodiment).

Here, the melanin level measured by the measuring instrument 7 is a value obtained by combining the concentration of the melanin pigment deposited on the scalp at the measurement point 51 and the concentration of the melanin pigment contained in the hair. That is, when the color of the hair of the subject 5 is black, it is estimated that the higher the melanin value, the greater the amount of hair sandwiched between the probe 70 and the measurement point 51 of the head 52. However, when the color of the hair of subject 5 is white (white hair), it is estimated that the lower the melanin value, the greater the amount of hair sandwiched between the probe 70 and the measurement point 51 of the head 52 . In the following description, the color of the hair of the subject 5 is black.

The acquiring unit 60 of the evaluation system 6 acquires seven measurement values (erythema value and melanin value) measured by the measuring device 7 from the measuring device 7 (step S2 in the flowchart of FIG. 5). The evaluation unit 61 causes the storage unit 62 to store seven measurement values F ₁ (Xk, Yk) acquired by the acquisition unit 60. However, Xk is the k-th erythema value of the 7 measurements performed in one measurement operation, and Y k is the k-th melanin value of the 7 measurements performed in the 1 measurement operation.

When the evaluation unit 61 receives seven measurement values F ₁ (Xk, Yk) from the acquisition unit 60, the evaluation unit 61 increments the number of measurements n (step S3 in the flowchart of FIG. 5). (Step S4 in the flowchart of FIG. 5). If the number of measurements n is less than five, the evaluation unit 61 starts the countdown timer (step S5 in the flowchart of FIG. 5), and waits until the countdown timer counts up a predetermined time (for example, 15 minutes) ( Step S6 of the flowchart of FIG.

When the countdown timer of the evaluation unit 61 counts up the predetermined time, the operator measures the erythema value and the melanin value of the measurement point 51 of the subject 5 seven times using the measuring device 7. The acquisition unit 60 of the evaluation system 6 acquires seven measurement values measured by the measuring device 7 from the measuring device 7 (step S2 in the flowchart of FIG. 5). The evaluation unit 61 causes the storage unit 62 to store seven measurement values F ₂ (Xk, Yk) acquired by the acquisition unit 60.

When the evaluation unit 61 receives seven measurement values F ₂ (Xk, Yk) from the acquisition unit 60, the evaluation unit 61 increments the number of measurements n (step S3 in the flowchart of FIG. 5). (Step S4 in the flowchart of FIG. 5). If the number of measurements n is less than five, the evaluation unit 61 starts the countdown timer (step S5 in the flowchart of FIG. 5), and waits until the countdown timer counts up a predetermined time (step in the flowchart of FIG. 5) S6).

The processes of steps S2 to S6 in the flowchart of FIG. 5 are repeated every 15 minutes until 60 minutes have elapsed from the start of the evaluation. As a result, the storage unit 62 of the evaluation system 6 stores 7 × 5 = 35 measured values F _i (X k, Y k) (where i = 1 to 5, k = 1 to 7). .

Subsequently, the evaluation unit 61 evaluates from among the seven measured values F _i (Xk, Yk) for each time from the first time (immediately after the start of evaluation) to the fifth time (after approximately 60 minutes from the start of evaluation). The candidate measurement values are selected (step S7 in the flowchart of FIG. 6). That is, since the color of the hair of the subject 5 is black, the larger the amount of hair sandwiched between the probe 70 of the measuring instrument 7 and the scalp of the measuring point 51, the more the measured value F _i (Xk, Yk) The melanin value Yk becomes high. Therefore, the evaluation unit 61 removes the measured value F _i (Xk, Yk) whose melanin value Yk is equal to or higher than the predetermined upper limit (first threshold value) Yth from the evaluation target (evaluation candidate). Inflammation can be assessed using measurements F _i (Xk, Yk), which are estimated to have relatively minor effects. However, it is preferable that the upper limit value Yth be set to a higher value as the melanin level of the scalp of the measurement location 51 of the subject 5 is higher.

FIG. 7 is a diagram in which seven measurement values F _i (Xk, Yk) of the i-th are plotted in a two-dimensional orthogonal coordinate system in which the erythema value is taken on the X axis and the melanin value is taken on the Y axis. The evaluation unit 61 determines four measured values F _i (X1, Y1), F _i (X2, Y2), F _i (having a melanin value Yk equal to or higher than an upper limit value Yth indicated by a broken line parallel to the X axis in FIG. 7). Three measurement values F _i (X 3, Y 3), F _i (X 5, Y 5), F _i (X 6, Y 6) excluding X 4, Y 4) and F _i (X 7, Y 7) are selected as measurement values of evaluation candidates .

The evaluation unit 61 calculates the average value of the erythema values in the measurement values of the evaluation candidates selected each time (step S8 in the flowchart of FIG. 6). The evaluation unit 61 determines whether the average value of the erythema values at each time decreases with the passage of time from the evaluation start time (when the headset 1 is removed from the head 52) (see the flowchart of FIG. 6). Step S9). In FIG. 8, the horizontal axis represents the elapsed time (0 minutes, 15 minutes, 30 minutes, 45 minutes, 60 minutes) from the time the headset 1 was removed from the head 52, and the average value of erythema values was vertical axis The line graph which represented the time change of the mean value (it abbreviates to an average value hereafter) of the erythema value of each time is shown. In FIG. 8, the average value of the time before the elapsed time of 0 minutes is an average value measured before (in advance) the subject 5 performs rehabilitation by the rehabilitation support system 100.

If the evaluation unit 61 determines that the average value of each time decreases with the lapse of time from the evaluation start time, next, the absolute value of the difference between the final value (after 60 minutes) and the prior average value The value is compared to a predetermined threshold (step S10 of the flowchart of FIG. 6). If the absolute value of the difference between the final average value and the previous average value is equal to or less than the threshold value, the evaluation unit 61 particularly issues a problem because the erythema at the measurement point 51 of the subject 5 is a temporary erythema. It is determined that there is no (evaluation result OK) (step S11 in the flowchart of FIG. 6). On the other hand, if the absolute value of the difference between the final average value and the previous average value is higher than the threshold, the evaluation unit 61 has a problem because the erythema at the measurement point 51 of the subject 5 is persistent erythema. It is determined that there is (evaluation result NG) (step S12 in the flowchart of FIG. 6). The evaluation unit 61 also determines that the evaluation result is NG when it is determined that the average value of each time does not decrease with the lapse of time from the evaluation start time (steps S9 and S12 in the flowchart of FIG. 6). Finally, the evaluation unit 61 notifies the notification unit 63 of the evaluation result (step S13 in the flowchart of FIG. 6).

The evaluation system 6 evaluates whether the inflammation (erythema) produced at the measurement site 51 of the subject 5 is temporary erythema or persistent erythema as described above, and notifies the evaluation result . If the evaluation result is NG, that is, if the erythema at the measurement point 51 is evaluated as persistent erythema, it is desirable to stop the rehabilitation for the subject 5 and treat the erythema occurring at the measurement point 51 of the subject 5 .

The operation of the evaluation system described above (the process executed by the microprocessor of the evaluation unit 61 in accordance with the program) is merely an example. In addition, although the evaluation unit 61 (microprocessor) performs final evaluation on the erythema of the measurement point 51, the worker measures the measurement point 51 based on the temporal change of the erythema value notified from the evaluation unit 61. Final evaluation may be performed on erythema of Also, the same function as that of the evaluation system 6 may be embodied in a non-temporary recording medium that records a program for causing a computer system to execute the evaluation method.

In addition, when the color of the hair of the subject 5 is white, the evaluation unit 61 removes the measurement value whose melanin value is less than a predetermined lower limit (second threshold) from the evaluation candidates, thereby making the hair (white hair) Inflammation can be assessed using measurements that are estimated to be relatively insensitive. However, it is preferable that the lower limit value is set to a lower value as the melanin level of the scalp of the measurement point 51 of the subject 5 is lower.

In the present embodiment, as a brain activity measuring device mounted on the head 52 of the subject 5, a head set configured to measure an electroencephalogram with an electroencephalogram electrode (electrode unit 11) in contact with the head 52 Although 1 is illustrated, the brain activity measuring device is not limited to the headset 1. Examples of brain activity measuring devices other than the headset 1 include, for example, functional near infrared spectroscopy devices. The functional near-infrared spectroscopy device includes a light-emitting device that emits near-infrared light, and a photoelectric conversion device that receives near-infrared light and converts the light into an electrical signal. A functional near infrared spectroscopy device brings a light emitting device and a photoelectric conversion device into contact with the scalp, emits near infrared light of the light emitting device into the brain, and reflects near infrared light (reflected light) reflected on the brain surface of the cerebral cortex The blood flow state (brain activity) of the brain surface of the cerebral cortex is measured by photoelectrically converting the That is, in the functional near infrared spectroscopy device, when the measurement location 51 of the head 52 is pushed by the light emitting device and the photoelectric conversion device, erythema may occur at the measurement location 51.

As described above, the inflammation evaluation system (6) according to the first aspect of the present disclosure evaluates the inflammation that occurs in the skin. The evaluation system (6) according to the first aspect is a measurement value including an erythema value at the measurement point (51) of the skin measured by the measuring instrument (7) and an intensity value (melanin value) different from the color of erythema An acquisition unit (60) for acquiring the The evaluation system (6) according to the first aspect includes an evaluation unit (61) that evaluates inflammation based on erythema values included in the plurality of measurement values acquired by the acquisition unit (60). The evaluation unit (61) selects a measurement value in which the intensity value (melanin value) in each of the plurality of measurement values is within a predetermined range as the measurement value of the evaluation candidate. An evaluation part (61) evaluates inflammation based on the erythema value contained in the measured value of an evaluation candidate.

The inflammation evaluation system (6) according to the first aspect estimates that the influence of body hair growing on the skin is small by excluding measurement values whose intensity value (melanin value) is not within a predetermined range from evaluation candidates. The inflammation is assessed based on the erythema value being As a result, the inflammation evaluation system (6) according to the first aspect can suppress the reduction in the accuracy of the evaluation.

The inflammation evaluation system (6) according to the second aspect of the present disclosure can be realized by a combination with the first aspect. In the evaluation system (6) according to the second aspect, the evaluation unit (61) determines a threshold value of at least one of a first threshold value and a second threshold value lower than the first threshold value. It is preferable to compare with the value. It is preferable that the evaluation unit (61) select a measurement value having a strength value equal to or less than a first threshold among the plurality of measurement values or a measurement value having a strength value equal to or more than a second threshold as measurement values of evaluation candidates.

The evaluation system (6) according to the second aspect can suppress the deterioration of the evaluation accuracy in any of the case where the color of body hair is black and the case where the color of body hair is white.

The inflammation evaluation system (6) according to the third aspect of the present disclosure can be realized by the combination with the first or second aspect. In the evaluation system (6) according to the third aspect, the acquisition unit (60) preferably acquires a plurality of measurement values measured by the measuring instrument (7) at predetermined time intervals. It is preferable that an evaluation part (61) selects the measurement value of an evaluation candidate from the several measurement value acquired for every predetermined time. It is preferable that the evaluation unit (61) evaluates the inflammation based on a temporal change of the erythema value in the measurement value of the evaluation candidate.

In the evaluation system (6) according to the third aspect, the evaluation unit (61) evaluates the inflammation based on the temporal change of the erythema value in the measurement value of the evaluation candidate, so that the erythema due to inflammation is temporary erythema. It can be evaluated whether it corresponds to any of erythema and persistent erythema.

The inflammation evaluation system (6) according to the fourth aspect of the present disclosure can be realized by combination with any one of the first to third aspects. The evaluation system (6) according to the fourth aspect preferably includes a storage unit (62) that stores the erythema value included in at least the measurement value of the evaluation candidate. It is preferable that an evaluation part (61) evaluates inflammation based on the erythema value memorize | stored in the memory | storage part (62).

The evaluation system (6) according to the fourth aspect evaluates the inflammation based on the erythema value stored in the storage unit (62) by the evaluation unit (61). Inflammation can be assessed.

The evaluation method according to the fifth aspect of the present disclosure is an evaluation method for evaluating inflammation generated in the skin. The evaluation method according to the fifth aspect acquires a measurement value including an intensity value of a color different from the color of the erythema and the color of the erythema at the measurement point (51) of the skin measured by the measuring instrument (7). The evaluation method according to the fifth aspect selects a measurement value in which the intensity value (melanin value) in each of the plurality of measurement values falls within a predetermined range as the measurement value of the evaluation candidate. The evaluation method which concerns on a 5th aspect evaluates inflammation based on the erythema value contained in the measured value of an evaluation candidate.

The evaluation method which concerns on a 5th aspect can aim at suppression of the precision fall of evaluation.

The program according to the sixth aspect of the present disclosure causes the computer system (evaluation unit 61) to execute the evaluation method according to the fifth aspect.

The program concerning a 6th mode can aim at control of a fall of accuracy of evaluation.

A non-transitory recording medium according to a seventh aspect of the present disclosure is a non-transitory recording medium readable by a computer system in which a program for causing a computer system to execute the evaluation method according to the fifth aspect is recorded. is there.

The non-temporary recording medium according to the seventh aspect can suppress deterioration in the accuracy of evaluation.

6 Inflammation evaluation system 7 Measuring instrument 51 Measurement point 60 Acquisition unit 61 Evaluation unit 62 Storage unit

Claims

An evaluation system for evaluating inflammation occurring in the skin, an acquisition unit acquiring a measurement value including an intensity value of a color different from the color of the erythema and the color of the erythema at the measurement site of the skin measured by a measuring device;
And an evaluation unit that evaluates inflammation based on the erythema values included in the plurality of measurement values acquired by the acquisition unit.
The evaluation unit selects a measurement value in which the intensity value in each of the plurality of measurement values falls within a predetermined range as a measurement value of an evaluation candidate, and the erythema value included in the measurement value of the evaluation candidate Assessment system of inflammation to assess inflammation based.
The evaluation unit compares the intensity value to at least one of a first threshold value and a second threshold value lower than the first threshold value, and selects one of a plurality of the measurement values. The inflammation evaluation system according to claim 1, wherein the measurement value having the intensity value equal to or less than the first threshold value or the measurement value having the intensity value equal to or more than the second threshold value is selected as the measurement value of the evaluation candidate.
The acquisition unit acquires a plurality of the measurement values measured by the measuring device at predetermined time intervals,
The evaluation unit selects measurement values of the evaluation candidate from a plurality of the measurement values acquired for each predetermined time, and evaluates inflammation based on a temporal change of the erythema value in the measurement values of the evaluation candidate. The evaluation system of inflammation according to claim 1 or 2.
A storage unit configured to store the erythema value included in at least the measurement value of the evaluation candidate;
The inflammation evaluation system according to any one of claims 1 to 3, wherein the evaluation unit evaluates inflammation based on the erythema value stored in the storage unit.
It is an evaluation method for evaluating the inflammation that occurs in the skin, and acquires a measurement value including an erythema value at the measurement site of the skin measured by a measuring instrument and an intensity value of a color different from the color of the erythema,
A measurement value in which the intensity value in each of the plurality of measurement values falls within a predetermined range is selected as a measurement value of an evaluation candidate, and inflammation is evaluated based on the erythema value included in the measurement value of the evaluation candidate How to evaluate
A program for causing a computer system to execute the evaluation method according to claim 5.
A non-transitory recording medium readable by a computer system, comprising a program for making the computer system execute the evaluation method according to claim 5.