CN111790017A

CN111790017A - Nuclear magnetic high-pressure injection system for controlling different injection procedures

Info

Publication number: CN111790017A
Application number: CN201911184520.1A
Authority: CN
Inventors: 张小元; 李燕
Original assignee: Nanjing Gankongtong Chemical Product Operation Portion
Current assignee: Nanjing Jusha Display Technology Co Ltd; Nanjing Jusha Medical Technology Co Ltd
Priority date: 2019-11-27
Filing date: 2019-11-27
Publication date: 2020-10-20

Abstract

The invention discloses a nuclear magnetic high-pressure injection system for controlling different injection procedures, which structurally comprises: the control display device, the power supply communication device and the nuclear magnetic filter are placed in a control room and work in a non-magnetic resonance environment; the injection operation device, the scanning room control device and the injection operation device bracket are placed in the nuclear magnetic room, the power supply communication device is connected with the control display device, the scanning room control device and the nuclear magnetic filter, provides power supply connection for the control display device and the nuclear magnetic filter, and is in communication connection with the control display device and the scanning room control device; the nuclear magnetic filter is connected with the scanning room control device, filters interference in a nuclear magnetic outdoor power supply and provides the power supply to the scanning room control unit; the scanning room control device is connected with the injection operating device and provides power supply for the injection operating device and communication with the control display device. The invention has scientific and reasonable design, simple structure and convenient operation.

Description

Nuclear magnetic high-pressure injection system for controlling different injection procedures

The technical field is as follows:

the invention relates to a nuclear magnetic high-pressure injection system for controlling different injection procedures, and belongs to the technical field of nuclear magnetic high-pressure injection systems.

Background art:

in many medical diagnostic and therapeutic procedures, a doctor or other person injects a contrast media into a patient in conjunction with Computed Tomography (CT), Digital Subtraction Angiography (DSA), magnetic resonance system (MR) imaging to assist in the diagnosis of the doctor. Contrast agents are typically delivered by manual or automatic injection devices, through veins or arteries to a detection site, and images of the desired tissue site are obtained by absorbing X-rays or changing the signal strength of the tissue in the volume under magnetic resonance, which can be displayed on a monitor and recorded.

The typical manual injection consists of a contrast medium source, a physiological saline source, a syringe capable of being injected by hands and a connecting pipeline. The contrast medium or saline is manually aspirated by the operator, and then the injection is manually performed by the operator. The flow rate, pressure and injection volume of the whole injection process are influenced by the force and technology of an operator, and the pressure required by injection is higher because the fluid is thicker and the speed is required to be higher during injection; the operator often does this which results in fatigue and the pressure, flow rate cannot be precisely controlled.

A typical automatic injection consists of a contrast source, a saline source, an injection device that is electrically controlled to move, a syringe that is connectable to the injection device, and a connecting line. An injection device with electrically controllable movement generally consists of an electric motor, a power supply system, and a control device that can modify the flow rate, the injected dose, the pressure parameters. In many systems, there is no interactive control between the operator and the power injector other than starting or stopping an injection.

While manual and automatic injectors already exist in the medical field, there is a general need for improved high pressure injector functionality, pressure feedback, human-machine interaction, and application environments. High-pressure injectors suitable for the application environments of Computed Tomography (CT), Digital Subtraction Angiography (DSA), magnetic resonance system (MR), etc. are continuously developed according to different design requirements and specific requirements.

The existing several mainstream fluid injection systems do not suck the liquid medicine by one key, and the existing several liquid medicine sucking modes are very inconvenient. There is a drug-sucking mode, which needs a hand to control the key, and another hand to hold the drug bottle to suck the drug; another medicine suction mode exists, the piston cannot be electrically controlled to move back and forth to suck medicine and exhaust air, and a plunger of a needle cylinder still needs to be manually pushed and pulled back and forth to suck medicine liquid and exhaust air; both of these two ways of sucking the liquid medicine are relatively inconvenient. The invention provides a mode for automatically sucking liquid medicine, which can automatically perform the process of sucking the liquid medicine by one key and avoid the inconvenience caused by manually sucking the liquid medicine.

There exist fluid injection systems described as follows: the rechargeable battery is used for supplying power, the number of times of injection which can be supported by the battery is small, the battery needs to be charged after being used every time, and the injection can be performed again after the charging is finished. This often results in the operator having to prepare two or more rechargeable batteries for backup. The invention improves the defect, adopts the mode of direct power supply of the AC power supply and avoids the trouble of repeated charging.

The invention content is as follows:

the invention provides an automatic interactive liquid injection device system which is suitable for being used in a magnetic resonance environment of 3.0T and below, solves the problem of accurate control of injection dosage, liquid flow rate, pressure parameters, staged injection and the like in the traditional typical manual injection and automatic injection processes, and provides more benefits for operators and patients.

A nuclear magnetic high pressure injection system for controlling different injection procedures, as shown in fig. 1, is an application scene diagram of a fluid injection system, and comprises a control display device (1), an injection operation device (2), a scan room control device (3), a power supply communication device (4), a nuclear magnetic filter (5), and an injection operation device support (6).

The control display device (1) comprises a colour Liquid Crystal Display (LCD) screen responsible for providing a Graphical User Interface (GUI) to the user and allowing information to be input to the control system via the touch screen; an injection operation device (2) for delivering a fluid (contrast medium or saline) to a patient; the scanning room control device (3) is used for controlling the injection operating device; the power supply communication device (4) is used for providing power supply and communication of the fluid injection system; the nuclear magnetic filter (5) is used for supplying power to the scanning room control device (3) after the direct-current power supply filters; the injection operation device bracket (6) is used for supporting the injection operation device (2) and can move.

Fig. 2 is a connection diagram of the fluid injection system, which shows the arrangement of the components of the fluid injection system in the magnetic resonance environment and the connection manner between the components.

The control display device (1), the power supply communication device (4) and the nuclear magnetic filter (5) are placed in a control room and work in a non-magnetic resonance environment; the injection operation device (2), the scanning room control device (3) and the injection operation device bracket (6) are placed in a nuclear magnetic resonance room and work in a magnetic resonance environment, wherein the injection operation device (2) and the injection operation device (6) are closer to a nuclear magnetic resonance system than the scanning room control device (3).

The power supply communication device (4) is connected with the control display device (1), the scanning room control device (3) and the nuclear magnetic filter (5), provides power supply connection for the control display device (1) and the nuclear magnetic filter (5), and is in communication connection with the control display device (1) and the scanning room control device (3); the nuclear magnetic filter (5) is connected with the scanning room control device (3) and used for filtering interference in a nuclear magnetic outdoor power supply and providing the power supply to the scanning room control unit (3); the scanning room control device (3) is connected with the injection operation device (2) and provides power supply for the injection operation device (2) and communication with the control display device (1).

As shown in fig. 3, which is a structural view of the injection operation device, the injection operation device (2) is shown to be composed from the outside:

the needle cylinder comprises a B side needle cylinder mounting hole (201), a front end cover (202), an A side needle cylinder mounting hole (203), an A side needle cylinder indicator lamp component (204), an elbow component (205), a lower shell (206), an upper shell (207), a stop button (208), a rear lamp (209), an injection/pause button (210), a film pasting key (211), an LED nixie tube (212) and a B side needle cylinder indicator lamp component (213).

Wherein, the stop button (208), the rear lamp shade (209), the injection/pause button (210), the pad pasting key (211) and the LED nixie tube (212) are arranged on the upper shell (207); the injection operating device (2) is mounted on the injection operating device bracket (6) by an elbow assembly (205).

Referring to fig. 2 and 3, after the injection operation device (2) is mounted on the injection operation bracket (6) through the elbow assembly (205), the elbow assembly allows the injection operation device (6) to rotate forward and backward by a certain angle with the vertical axis of the elbow assembly as the axis, and allows the injection operation device head to rotate forward and backward by any angle with the horizontal axis of the elbow assembly as the axis, and the injection operation device head can be kept at any angular position within the rotation range as shown in fig. 4, so as to be suitable for different use scenarios; further description of the elbow assembly is found in chinese patent No.: discussed in CN 205181924U.

As shown in fig. 3, the injection operation device (6) includes 3 indicator light parts, which are an a-side syringe indicator light assembly (204), a B-side syringe indicator light assembly (213), and a rear light (209), respectively; the side A indicator light is a green LED, the side B indicator light is a blue LED, the two sides of the rear light are respectively the green LED and the blue LED (the indicator light comprises an LED, a lamp tube and a cold light band), and the side A indicator light and the side B indicator light correspond to each other (the color of the indicator light is not limited to green and blue).

Referring to fig. 5 to 10, there are shown schematic diagrams of the rotation component, the mounting component and the insertion and extraction of the syringe, wherein the insertion position of the syringe is detected and fixed, and the specific implementation manner is as follows:

as shown in fig. 5, 216, 214 are rotating members, 215 are fixed members; the main structure of the rotating part (214) is as shown in fig. 7, and the rotating part comprises a rotating part main body (2141), a limiting block a (2142), an optical coupling light blocking claw (2143), a limiting block B (2144), and 4 limiting spherical grooves (2145) on the back; the main structure of the fixing part (215) is as shown in fig. 8, and mainly comprises a limiting column A (2151), a detection optical coupler A (2152), a fixing part main body (2153), a detection optical coupler B (2154), 2 ball spring plungers (2155) and a limiting column B (2156).

In the use process of the whole device, one surface of the rotating part, which is provided with the limiting spherical groove, is attached to one surface of the fixed part, which is provided with the ball spring plunger, and the rotating part rotates and slides clockwise and anticlockwise in the limiting groove of the fixed part. The assembled configuration is shown in figures 9 and 10, with the rotary members rotating synchronously with the rotation of the needle cylinder.

When the needle cylinder rotates clockwise to the right position, the limiting block B of the rotating part can touch the limiting column B of the fixing part as shown in fig. 9, and meanwhile, the claw can be clamped in the middle of the optical coupler B to trigger a right-position signal. The spring plunger on the back of the stationary part also springs into the spherical recess of the rotating part, giving a "snap" sound.

When the needle cylinder rotates in place anticlockwise, the limiting block A of the rotating component can touch the limiting column A of the fixing component as shown in figure 10, and meanwhile, the clamping jaw can be clamped in the middle of the optical coupler A to trigger a signal in place. The spring plunger on the back of the stationary part also springs into the spherical recess of the rotating part, giving a "snap" sound.

And the two states are subjected to combined analysis, the optocoupler is defined as 1 when in a triggering state, and the optocoupler is defined as 0 when in disconnection. (Note: the syringe can be released only when it is in place clockwise, and the syringe body cannot be released due to structural restrictions in other states)

As shown in fig. 11, an example of a key is disclosed, which provides a human-machine interaction application of the injection operation device (2), and the operator mainly uses an a-side "+" key (21101), an a-automatic loading key (21102), an a-side "-" key (21103), an a-high speed forward key (21104), an a-low speed forward key (21105), an a-low speed backward key (21106), an a-high speed backward key (21107), an ARM key (21108), a B-high speed backward key (21109), a B-low speed backward key (21110), a B-low speed forward key (21111), a B-high speed forward key (21112), a B-side "-" key (21113), a B-automatic loading key (21114), a B-side "+" key (21115), an AUTO key (21116), an AIR key (21117), and a MANU key (21118).

The example provides a practical way of operation, facilitating interaction between the operator and the machine; the automatic liquid medicine loading operation mode is provided, the defect that the partial machine type on the market can only load liquid medicine manually at present is overcome, and the automatic liquid medicine loading operation mode is generally carried out as follows: clicking an AUTO key to enable loading keys and a dosage adding and subtracting key on the A side and the B side, wherein the dosage is default to be the maximum capacity of the syringe, and the dosage can be added or subtracted on the A side or the B side through the adding and subtracting key; after the dosage is confirmed, the A-automatic loading button or the B-automatic loading button is clicked to automatically load the liquid medicine.

Injection operating means (2) contain an inclination sensor, and the location is installed in the system, detects the angular relation between injection head and the horizon, gathers through the system and handles this sensor signal, and LED charactron (212) of injection operating means (2) will be according to present injection head and the digital display mode of the angle of pitch relation automatic adjustment at horizon for accords with operating personnel natural visual angle, when having solved the injection aircraft nose and injecting downwards, the inconvenient operating personnel of digital display observed the problem.

In one embodiment, as shown in fig. 4, the injection operating device is shown in fig. 12a when the injection head is at an elevation angle a to the ground plane; the display of the injection operating device when the injection head is in a depression angle b relationship with the ground plane is shown in fig. 12 b.

If the ethernet is used for communication in a magnetic resonance environment, the network cable is usually greatly interfered, which affects communication between devices, and is likely to cause phenomena such as communication packet loss and device operation failure. The optical fiber transmission is applied to the magnetic resonance environment as a stable and interference-free transmission mode, so that the problem is well solved.

The invention discloses an embodiment, as shown in fig. 2, a power supply communication device (4) is in a non-magnetic resonance environment in a control room, a scanning room control device (3) is in a nuclear magnetic environment, and the scanning room control device (3) is connected with the power supply communication device (4) through an optical fiber, so that reliable communication connection between the inside and the outside of the nuclear magnetic room is ensured.

Referring to fig. 2, an injector head is defined as an operable means for delivering fluid to a patient, including two syringe thermal sleeve attachments for maintaining the temperature of the fluid in the syringe, maintaining fluid flow, and reducing patient discomfort when the fluid is delivered to the patient.

As shown in fig. 13, a syringe thermal insulating sleeve attachment (8) comprises a heating assembly (802) which can be clamped on the outer wall of the syringe, and a transmission line (801) with spiral elastic extension, which is inserted on the rear cover shell of the injection operation device (2) to provide the function of insulating the syringe.

Referring to fig. 2, an injector head is defined as an operable means for delivering fluid to a patient, comprising a syringe, a bubble detection accessory, optionally mounted on an interface of a rear housing of the injector head, for detecting the presence of a bubble in an infusion line to avoid injury to the patient during delivery of the fluid.

As shown in fig. 14, one bubble detection sensor (9) includes: a sensor detecting head (901) clamped on the infusion tube (10), and a transmission line (902).

When the injection handpiece delivers liquid to a patient, the bubble sensor detects the liquid flow in the infusion tube in real time, if bubbles pass through the monitoring position of the sensor, the sensor sends a signal for monitoring the bubbles to the system, and the system performs corresponding treatment.

Referring to fig. 3 and 5, the injector head also includes two sets of actuation systems that are fixed inside the injector head and configured to push or retract the syringe plunger for the purpose of delivering fluid to a patient or drawing fluid from a fluid reservoir into the syringe. Fig. 15 shows a perspective view of the actuator system, comprising: a side B push rod (218), a side A push rod (219), a potentiometer B (220), a potentiometer A (221), an ultrasonic motor A (222) and an ultrasonic motor B (223).

When the system receives an actuation command, the system activates an actuation motor (222, 223), which, through a geared transmission, pushes a ram (218, 219) forward or backward, and the forward end of the ram is hooked to the syringe piston, thereby moving the syringe piston and delivering fluid to a patient or drawing fluid from a fluid reservoir.

Referring to fig. 15, the injection operation device (2) includes an ultrasonic motor a (222) and an ultrasonic motor B, the ultrasonic motors have good electromagnetic compatibility, no coil and no winding, do not generate a magnetic field and are not interfered by an external magnetic field during operation, greatly reduce the influence on magnetic resonance and ensure the motion performance of the device when used in a magnetic resonance environment. The invention controls the ultrasonic motor to work in a strong magnetic environment through a unique control algorithm, and the following explains an ultrasonic motor control algorithm example:

the system adopts a control algorithm, the algorithm adopts a multi-closed-loop feedback control design and comprises three control closed loops, namely a speed loop, a position loop and a pressure loop; the speed closed loop is used as an inner loop of the control system, the output of the track planning is used as a control setting, the speed of the motor can be driven according to a speed curve designed by the track planning of the system, and the reasonability of the injection process is ensured; the position ring is used as a system outer ring, the injection dose and the injection speed set by the system are used as input, system track planning is carried out, the planned output is used as the given value of the speed ring, and the injection dose precision of the system is ensured; in order to ensure the pressure limit value in the injection process of the system, a pressure closed loop is introduced in closed-loop control, and when the injection pressure of the system reaches a set limit value, the injection speed of the system is actively reduced, so that the injection safety is ensured; although the piezoelectric ceramic needs high-voltage driving, the polarized ceramic piece still has certain requirements on driving voltage, otherwise, the ceramic piece can be punctured to damage the ultrasonic motor body; namely, in the driving process of the ultrasonic motor, the driving voltage is smaller than the breakdown voltage of the ceramic plate. In addition, the temperature rise speed of the motor is accelerated along with the increase of the injection current of the ceramic chip when the driving voltage of the ultrasonic motor rises, so that the continuous operation time of the ultrasonic motor is seriously influenced, otherwise, the service life of the motor is seriously damaged due to overhigh temperature rise of the ceramic chip.

In the ultrasonic motor driving system, the series matching mode and the parallel matching mode can be divided according to an LC matching mode. In the series matching type driving system, the amplitude of the motor driving voltage is continuously increased along with the increase of the driving frequency. In high pressure syringe ultrasonic motor applications, the motor is required to operate over a large speed range, i.e., a large range of drive frequencies. However, the scheme proposed in the market at present does not pay attention to the problem of adjusting the input voltage of the motor under the drive of the ultrasonic motor in a large speed range, and has a large hidden trouble, and the invention provides a scheme for explaining the problem:

in the ultrasonic motor closed-loop control driving system, the motor driving frequency is judged in real time.

When the expected speed of the ultrasonic motor is higher than the actual speed, the closed-loop control system can automatically reduce the driving frequency of the ultrasonic motor and improve the actual rotating speed of the motor.

When the expected speed of the ultrasonic motor is lower than the actual speed, the closed-loop control system can improve the driving frequency of the ultrasonic motor and reduce the rotating speed of the motor.

In the process of reducing and increasing the driving frequency of the ultrasonic motor, when the driving frequency exceeds a critical value, the control system switches the inductor and adjusts the range of the input driving voltage of the ultrasonic motor.

This scheme is further described below in conjunction with FIG. 17 and an example:

referring to fig. 17, shown therein is an example for illustrating this scheme only and is not intended to limit it.

The switching of the matching inductance of the ultrasonic motor driving circuit occurs during the driving of the motor.

In order to prevent the situation that the inductance is switched continuously near a certain frequency, a relay characteristic curve switching mechanism is adopted, and 2 critical frequency points, namely an upper-bound frequency critical point and a lower-bound critical frequency point, are arranged in a driver, wherein the frequency of the upper-bound frequency critical point is greater than that of the lower-bound critical frequency point.

During driving, the driver monitors the input driving frequency in real time. When the driving frequency is monotonically increased and exceeds the upper-bound critical frequency, the driver switches the inductor action, the short-circuit part matches the inductor, the matching inductance value of the ultrasonic motor is reduced, the waveform voltage of the motor driving is reduced, the injection current of the motor is reduced, the temperature rise of the motor is reduced, and the driving frequency range of the motor body is adjusted. When the driving frequency is monotonically decreased and crosses the lower-bound critical frequency, the driver performs the inductance switching action again, recovers and introduces the short-circuited matching inductance, improves the matching inductance value of the driving circuit, improves the driving waveform voltage of the motor, and simultaneously adjusts the torque which can be output by the motor and improves the output power of the motor.

Referring to fig. 15, each group of actuating systems of the injection handpiece further comprises a pressure sensor, the pressure sensor is used for detecting the injection pressure in the syringe in real time when liquid is delivered to a patient in the working process, the detection precision is high, the response is sensitive, and the system adjusts the output of the actuating motor according to the feedback information of the pressure sensor so as to meet the injection scheme preset by an operator.

Compared with the mode of judging the pressure in the syringe by detecting the current of the actuating motor and then calculating the torque of the motor, the mode of directly detecting the pressure in the syringe by using the pressure sensor shortens the reaction time, avoids unnecessary calculation errors and is safer and more effective.

In one embodiment, as shown in fig. 18, which is a cross-sectional view of a set of actuator motor structures, the pressure sensor detection is implemented as follows: external pressure is transmitted to the push rod (219) through the syringe piston, transmitted to the screw nut (21901) through the push rod, transmitted to the bearing end of the pressure sensor (21902) through the annular retainer ring at the tail end of the screw nut, further transmitted to the pressure strain gauge through the stress of the bearing end face, and finally detected.

Referring to fig. 1 and 2, the MR contrast injection apparatus disclosed in the present invention comprises a control display device (1) disposed in a control room and operatively connected to a power box through a cable.

As shown in fig. 19a, 19b and 19c, which are schematic structural diagrams of the control display device, a front cover housing (102) is provided with: a touch screen display (101) for the user interface of the operator for remotely operating the injector head for a liquid injection procedure, a system power button (103) for enabling and disabling the system power supply in case of normal operation of the power supply box, a stop button (104) for stopping the injection procedure during an injection procedure, an injection/pause button (105) for enabling or pausing an injection procedure.

A rear cover housing (107) having mounted thereon: a manual switch shelf (108) for placing a manual switch, a manual switch socket (109) for insertion of a manual switch connector, a power box cable socket (110) for insertion of a power and communication cable connecting the power box, a brightness increase button (111) for increasing the brightness of the liquid crystal display, and a brightness decrease button (112) for decreasing the brightness of the liquid crystal display.

The control display device bracket (106) is fixedly arranged on the rear cover shell, is used for supporting the shell with a changeable inclination angle and all parts in the shell, and comprises a damping bracket rotating shaft (1061) which allows the shell to use the rotating shaft as the axis, can randomly adjust the inclination angle according to the use habit of an operator, can keep the inclination angle, and provides the optimal operation visual angle for the operator.

Referring to fig. 19a, the control display device includes a touch display screen (101), which is formed by covering the touch display screen on the liquid crystal display screen, and has control and display functions, and an operator can control the injection handpiece to perform a liquid injection procedure by operating the control display device.

In one embodiment, as shown in fig. 20, a graphical interface displayed by the lcd panel includes:

status display field (a): is used for indicating the equipment operation state of the current system, whether the equipment operation state is operated by the control display device (1) or the injection operation device (2), or whether the equipment operation state and the injection operation device are not operated; respectively, far-end control, near-end control, and standby.

Scenario information display field (B): for displaying the completed injection protocol, the total injection volume to be used, and the total time required for the current set.

Lock ready button bar (C): contains a "protocol lock" button for locking the protocol and a "ready" button for preparing the syringe.

Scheme setup column (D): the setting of detailed parameters for the injection protocol includes setting parameters such as injection stage, injection volume, injection rate, KVO, delay, pressure limit, etc.

Model display field (E): the machine model of the equipment is displayed.

Syringe status display field (F): and is used for displaying the current state of the syringe, including whether the syringe is inserted in place and the current liquid volume in the syringe.

Prompt field (G): and the display module is used for displaying the operation content of the next step and guiding the operator to carry out correct operation.

History and system settings field (H): for reviewing the history of the injection protocol and for performing the setting of system parameters.

As shown in fig. 21 and 22, when the injector head performs injection, the lcd displays a real-time pressure curve according to the feedback value of the pressure sensor, and displays the pressure curve of the complete stage again when the injection is completed.

As shown in fig. 21, which shows the pressure profile displayed by the injection device during injection: the abscissa of the pressure curve is the duration of the scheme, the ordinate is the pressure value, the horizontal line is the pressure limit, and an operator can control whether the target blood vessel is blocked or abnormal in real time by checking the pressure curve, so that the safety of injection is effectively guaranteed.

As shown in fig. 22, which shows the complete pressure profile of the injection device during injection: for operator review and judgment.

The invention discloses a calculator for calculating the needed dosage of contrast medium based on body weight; the input parameters are as follows: patient dose (ml/kg), patient weight (kg or lbs), patient age (year), and a recommended injection dose by calculating the relationship between patient dose, patient weight, and patient age, providing more convenient use for the operator.

One embodiment is shown in fig. 23, where the system stores the names of various used contrast agents and their concentrations (mmol/ml), vial sizes (ml), doses (ml/kg) for selection and viewing by the operator, and the contrast agent parameters can be set and stored via the "set" button; the input parameters comprise the dosage (ml/kg) of the patient, the weight (lbs or kg) of the patient and the age (year) of the patient, and the recommended injection dosage value can be obtained by calculating the relationship among the three parameters; the reset button can perform resetting of the numerical value.

The invention discloses a calculator applied to glomerular filtration rate estimation (eGFR), which aims to assist an operator to judge whether a patient can be subjected to radiography or not; glomerular Filtration Rate (GFR) is the amount of filtrate produced by both kidneys per unit time, and is around 125ml/min for normal adults, and the ratio of glomerular filtration rate to renal plasma flow is called the filtration fraction. The kidney plasma flow rate was approximately 660ml per minute, so the filtration fraction was (125/660) × 100% ═ 19%. This result indicates that about 1/5 of plasma flowing through the kidney was filtered from the glomeruli into the cystic cavity to produce raw urine. Glomerular filtration rate and filtration score are measures of renal function.

The input parameters comprise selected calculation formula, serum creatinine value (mg/dl), race, sex and age, an estimated glomerular filtration rate is calculated by a specific selected formula, and the operator's experience is used to judge whether the angiography can be performed.

One embodiment is shown in FIG. 24, where the system provides a "set" button that presets all formulas and level distinctions to be used: the formulas include, but are not limited to, five formulas such as MDRD, Cockcroft-Gault, Modified Cockcroft-Gault, CKD-EPI, Bedside Schwartz, and the like, and the levels distinguish optional multiple levels and set limits to indicate ranges; the input parameters comprise serum creatinine values, race, gender and age; an estimated glomerular filtration rate value is ultimately obtained by setting these parameters.

Referring to fig. 1 and 2, the MR imaging apparatus of the present invention comprises an injection operation device holder (6) for supporting and carrying an injection operation device (3). The perspective of the support structure is shown in fig. 25, which comprises: 1 support sleeve (601) that has locking pin (6011), 1 support casing (602), 1 hold up hand dish (603) that the hole (6032, 6033) and 1 handrail (6031) are settled by 2 liquid storage, a plurality of area lock universal castor (404).

Wherein support sleeve (601) is configured to be the part of the bell and spigot joint installation with return bend subassembly (205), through the locking and the unblock of locking pin, the injection head can be convenient fixed with the support and separation, handrail dish (603) are fixed on support casing (602), and a plurality of area lock universal castor (604) are installed to the casing bottom, and when the castor unblock, operating personnel can promote the handrail dish, the free removal support position to lock the castor when arriving suitable position, with the position of guaranteeing the support does not change.

Referring to fig. 1 and 2, the MR contrast injector system of the present invention has a stand-type injector head that can be replaced with a stand-type injector head, as shown in fig. 26, wherein the stand-type injector head (7) comprises: a column sleeve (701) for carrying an injection head, mounted and fixed on the column elbow (706), two locking rings (707), used for locking the liquid medicine bracket at one side of the re-standing column, an opening (708) on the standing column is reserved for wiring from the inside of the pipeline, a base (709) is used for fixing the standing column, the base extends outwards to form a plurality of support feet (710), each support foot is provided with a universal caster (711) with a lock, an operator can freely adjust the position of the upright post support and lock the caster after reaching a target position, so as to ensure that the position of the upright post bracket is not changed, a liquid medicine hook bracket with adjustable height is convenient for the practical use of a user, the liquid medicine support comprises two hooks (702), which are arranged on a telescopic rod (703) and used for hooking a liquid medicine container, and the telescopic rod is locked on a main body rod (705) of the liquid medicine support by a locking buckle (704).

Description of the drawings:

for ease of illustration, the invention is described in detail by the following detailed description and the accompanying drawings.

FIG. 1 fluid injection system application scenario

FIG. 2 fluid injection system connection diagram

FIG. 3 Structure of injection operation device

FIG. 4 injection operating device-rotation angle diagram

FIG. 5 injection handling device-disassembled view

FIG. 6 Syringe installation

FIG. 7 Syringe rotation Member views

FIG. 8 Syringe mount drawings

FIG. 9 is a schematic view of the syringe inserted in place

FIG. 10 is a schematic view of the syringe in position

FIG. 11 film-covered key

FIG. 12a injection operating device facing upwards

Figure 12b injection operating device downwards

Figure 13 syringe thermal insulation cover

FIG. 14 bubble sensor

FIG. 15 perspective view of an actuation system

FIG. 16 an example control algorithm

FIG. 17 flow chart of inductance switching during ultrasonic motor drive

FIG. 18 is a sectional view of an actuator motor

FIGS. 19a, 19b, and 19c are schematic structural views of a control display device

FIG. 20 control display device-operation interface

FIG. 21 in the course of injection

FIG. 22 completion of injection

FIG. 23 contrast agent injection dose calculator for calculating based on body weight

FIG. 24A eGFR (glomerular filtration rate estimation) calculator

FIG. 25 injection operating device holder

FIG. 26 pillar form

The specific implementation mode is as follows:

in order that the objects, aspects and advantages of the invention will become more apparent, the invention will be described by way of example only, and in connection with the accompanying drawings. It is to be understood that such description is merely illustrative and not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.

the system adopts a control algorithm, the algorithm adopts a multi-closed-loop feedback control design and comprises three control closed loops, namely a speed loop, a position loop and a pressure loop; the speed closed loop is used as an inner loop of the control system, the output of the track planning is used as a control setting, the speed of the motor can be driven according to a speed curve designed by the track planning of the system, and the reasonability of the injection process is ensured; the position ring is used as a system outer ring, the injection dose and the injection speed set by the system are used as input, system track planning is carried out, the planned output is used as the given value of the speed ring, and the injection dose precision of the system is ensured; in order to ensure the pressure limit value in the injection process of the system, a pressure closed loop is introduced in closed-loop control, and when the injection pressure of the system reaches a set limit value, the injection speed of the system is actively reduced, so that the injection safety is ensured;

Model display field (E): the machine model of the equipment is displayed.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A nuclear magnetic high pressure injection system for controlling different injection procedures, characterized by: the structure includes: the device comprises a control display device (1), an injection operating device (2), a scanning room control device (3), a power supply communication device (4), a nuclear magnetic filter (5) and an injection operating device bracket (6), wherein the control display device (1) comprises a color Liquid Crystal Display (LCD) screen, and the control display device (1), the power supply communication device (4) and the nuclear magnetic filter (5) are placed in a control room and work in a non-magnetic resonance environment; the injection operation device (2), the scanning room control device (3) and the injection operation device bracket (6) are placed in the nuclear magnetic room, the power supply communication device (4) is connected with the control display device (1), the scanning room control device (3) and the nuclear magnetic filter (5) to provide power supply connection of the control display device (1) and the nuclear magnetic filter (5) and is in communication connection with the control display device (1) and the scanning room control device (3); the nuclear magnetic filter (5) is connected with the scanning room control device (3) and used for filtering interference in a nuclear magnetic outdoor power supply and providing the power supply to the scanning room control unit (3); the scanning room control device (3) is connected with the injection operation device (2) and provides power supply for the injection operation device (2) and communication with the control display device (1), the B side needle cylinder mounting hole (201), the front end cover (202), the A side needle cylinder mounting hole (203), the A side needle cylinder indicating lamp assembly (204), the bent pipe assembly (205), the lower shell (206), the upper shell (207), the stop button (208), the rear lamp (209), the injection/pause button (210), the film pasting key (211), the LED nixie tube (212) and the B side needle cylinder indicating lamp assembly (213), and the stop button (208), the rear lamp cover (209), the injection/pause button (210), the film pasting key (211) and the LED nixie tube (212) are arranged on the upper shell (207); the injection operation device (2) is arranged on the injection operation device bracket (6) through the elbow assembly (205), after the injection operation device (2) is arranged on the injection operation bracket (6) through the elbow assembly (205), the injection operation device (6) comprises 3 indicator lamp parts which are respectively an A-side syringe indicator lamp assembly (204), a B-side syringe indicator lamp assembly (213) and a back lamp (209); the side A indicator light is a green LED, the side B indicator light is a blue LED, and the green LED and the blue LED are respectively arranged on two sides of the rear light and correspond to the side A indicator light and the side B indicator light.

2. A nuclear magnetic high pressure injection system for controlling different injection procedures according to claim 1, characterized in that: 214 be rotary part, 215 is fixed part, rotary part (214) are by rotary part main part (2141), stopper A (2142), the opto-coupler is in the light jack catch (2143), 4 spacing spherical groove (2145) at stopper B (2144) and the back are constituteed, fixed part (215) mainly comprise spacing post A (2151), detect opto-coupler A (2152), fixed part main part (2153), detect opto-coupler B (2154), 2 ball spring plunger (2155) and spacing post B (2156).

3. A nuclear magnetic high pressure injection system for controlling different injection procedures according to claim 1, characterized in that: syringe insulation cover annex (8) contain one can block heating element (802) on the syringe outer wall to and a take spiral elasticity extension transmission line (801), peg graft on injection operating means (2) back lid casing, provide the heat retaining function of syringe, bubble detection sensor (9) contain: a sensor detecting head (901) clamped on the infusion tube (10), and a transmission line (902).

4. A nuclear magnetic high pressure injection system for controlling different injection procedures according to claim 1, characterized in that: the injection handpiece also comprises two groups of actuating systems, and the actuating systems structurally comprise: a side B push rod (218), a side A push rod (219), a potentiometer B (220), a potentiometer A (221), an ultrasonic motor A (222) and an ultrasonic motor B (223).