ZA932458B - Naphtoquinones and their use. - Google Patents

Naphtoquinones and their use.

Info

Publication number
ZA932458B
ZA932458B ZA932458A ZA932458A ZA932458B ZA 932458 B ZA932458 B ZA 932458B ZA 932458 A ZA932458 A ZA 932458A ZA 932458 A ZA932458 A ZA 932458A ZA 932458 B ZA932458 B ZA 932458B
Authority
ZA
South Africa
Prior art keywords
naphtoquinones
Prior art date
Application number
ZA932458A
Inventor
Alan Thomas Hudson
Clive Leonard Yeates
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZA932458B publication Critical patent/ZA932458B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA932458A 1992-04-06 1993-04-05 Naphtoquinones and their use. ZA932458B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929207517A GB9207517D0 (en) 1992-04-06 1992-04-06 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
ZA932458B true ZA932458B (en) 1994-10-05

Family

ID=10713546

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932458A ZA932458B (en) 1992-04-06 1993-04-05 Naphtoquinones and their use.

Country Status (16)

Country Link
EP (1) EP0634996A1 (en)
JP (1) JPH07505388A (en)
KR (1) KR950700874A (en)
CN (1) CN1083048A (en)
AU (1) AU3899293A (en)
CA (1) CA2133744A1 (en)
CZ (1) CZ242994A3 (en)
FI (1) FI944657A (en)
GB (1) GB9207517D0 (en)
HU (1) HUT68937A (en)
IL (1) IL105322A0 (en)
MX (1) MX9301962A (en)
NO (1) NO943737L (en)
SK (1) SK120994A3 (en)
WO (1) WO1993020044A1 (en)
ZA (1) ZA932458B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9169232B2 (en) * 2011-09-16 2015-10-27 Alkem Laboratories Limited 3-(5-methyl-2-oxo-l, 3-dioxol-4-yl) methyloxy-2-trans-[(4-chloro phenyl) cyclohexyl][1,4]naphthaquinone-atovaquone prodrug
CN109715147A (en) 2016-06-20 2019-05-03 斯克利普斯研究院 Anti-malarial composition and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485116A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
GB8310141D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
DE68928964T2 (en) * 1988-08-16 1999-07-29 Wellcome Found New naphthoquinones and their use as medicines

Also Published As

Publication number Publication date
HUT68937A (en) 1995-08-28
SK120994A3 (en) 1995-07-11
CZ242994A3 (en) 1995-06-14
AU3899293A (en) 1993-11-08
NO943737D0 (en) 1994-10-05
JPH07505388A (en) 1995-06-15
KR950700874A (en) 1995-02-20
CA2133744A1 (en) 1993-10-14
WO1993020044A1 (en) 1993-10-14
NO943737L (en) 1994-11-29
CN1083048A (en) 1994-03-02
EP0634996A1 (en) 1995-01-25
IL105322A0 (en) 1993-08-18
HU9402850D0 (en) 1995-01-30
FI944657A (en) 1994-12-02
GB9207517D0 (en) 1992-05-20
MX9301962A (en) 1993-11-01
FI944657A0 (en) 1994-10-05

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