WO2021129067A1

WO2021129067A1 - Method, system and device for formulating and implementing personalized paced breathing exercise prescription

Info

Publication number: WO2021129067A1
Application number: PCT/CN2020/121357
Authority: WO
Inventors: 吴健康
Original assignee: 南京宁康中科医疗技术有限公司
Priority date: 2019-12-25
Filing date: 2020-10-16
Publication date: 2021-07-01
Also published as: CN111000541A

Abstract

A method, system and device for formulating and implementing a personalized paced breathing exercise prescription. The method comprises: defining a personalized paced breathing exercise prescription (210); guiding a testee to be subjected to a cardiopulmonary resonance test: when the testee is in a resting state, guiding the testee to breathe freely and carry out guided breathing respectively, and calculating cardiopulmonary resonance indices according to synchronously measured electrocardio signals and breathing signals (220); formulating a personalized paced breathing exercise prescription according to the cardiopulmonary resonance test result of the testee: selecting a guided breathing frequency for the optimal cardiopulmonary resonance indices of the testee as a breathing frequency parameter of a breathing exercise, and taking values corresponding to the other parameters in the personalized paced breathing exercise prescription as default values (230); and according to the personalized paced breathing exercise prescription, guiding the testee to carry out breathing exercises (240). The cardiopulmonary resonance state of a testee is evaluated by taking cardiopulmonary resonance indices as key indexes, and thereby a personalized paced breathing exercise prescription is formulated.

Description

Method, system and device for formulating and implementing personalized deep breathing training prescription

Technical field

This application relates to the technical field of physiological information processing, and in particular to a method, system and device for formulating and implementing a personalized deep breathing training prescription.

Background technique

The human body is a complex system, and evaluation of a person's health must be done at the system level. The theory of internal balance (Hemeostatis) established by Professor Cannon of Harvard University believes that the sympathetic and parasympathetic nerves in the autonomic nerves, one by one, regulate the three major systems of the human body and maintain human health. It is manifested in the control parameters such as temperature, heart rate, and blood pressure. Change around a certain value.

The health care of sub-healthy people and the rehabilitation of patients require evaluation of the state of the human autonomic nervous system and conditioning based on the evaluation results. Taking pregnant women as an example, the health risks of common psychological abnormalities (tension, anxiety, depression, etc.) and related pregnancy complications (pregnancy and postpartum depression, gestational hypertension, diabetes and other comorbidities, etc.) are fundamentally due to internal and external health risks The pressure of the environment and the influence of hormones during pregnancy breaks the balance of the autonomic nervous system, which leads to the disorder of the ability to regulate the normal operation of the internal organs of the body. At the same time, the abnormal mental state causes the mother to release cortisol, which damages the development of the fetal hypothalamus-pituitary-adrenal axis, which will have a negative impact on the growth of the fetus. Therefore, scientifically and effectively assessing the balance state of the autonomic nervous system and regulating it through personalized intervention can fundamentally alleviate the psychological abnormalities of pregnant women during pregnancy and the corresponding pregnancy complications.

Heart rate variability biofeedback originated in the former Soviet Union in the 1970s, and was further researched and promoted in the United States by Professor Lehter in the 1990s. However, there is no scientific basis in the world to prove that heart rate variability can be used as an evaluation indicator of mental health.

The evaluation of the autonomic nervous system can be obtained from its regulation of the cardiopulmonary system. A large number of international studies have proved that the level of respiratory heart rate modulation (RSA, also known as "respiratory sinus arrhythmia") is directly related to the physical and mental health of the human body, and can represent the degree of parasympathetic nerve activity. Among them, the quantitative and accurate evaluation index of RSA has become the key to related scientific research and clinical application. However, while the autonomic nerve regulates the cardiopulmonary metabolism system, it is also affected by various factors such as external environment, internal infection, exercise, and psychology, making the research of RSA evaluation indicators and evaluation methods face great difficulties. Simply using heart rate variability, because the factors that cause heart rate changes are too many and too complicated, the metrics provided are often not stable and repeatable.

Respiratory training has shown potential in improving respiratory function and improving autonomic balance. At present, the respiratory training in the respiratory department of the hospital advocates abdominal breathing to improve ventilation, strengthen the respiratory muscles, and enhance the coordination of breathing. However, domestic and foreign respiratory organizations have not put forward any quantitative description of respiratory training. In the field of heart rate variability biofeedback research, there are some studies on respiratory rate and inspiration-to-expiration ratio. Taking the amplitude of heart rate variability as the standard, it is concluded that the optimal respiratory rate is about 6 times per minute, which varies from person to person. However, taking the magnitude of heart rate variability as an evaluation measure lacks physiological basis. The breathing rate of 6 breaths per minute can only be used as a reference. That is to say, there is no clear scientific definition of personalized breathing training prescriptions, and there is no corresponding method for evaluating the state of the human autonomic nervous system and formulating personalized deep breathing prescriptions, as well as training guidance and monitoring systems based on the prescriptions.

Summary of the invention

The purpose of the embodiments of this application is to provide a method, system and device for the formulation and implementation of a personalized deep breathing training prescription. The cardiopulmonary harmony series indicators are used as key indicators to establish a standardized method for evaluating the testee’s cardiopulmonary harmony state, which can then be used for Formulate a personalized deep breathing training prescription.

In the first aspect, the embodiments of the present application provide a method for formulating and implementing a personalized deep breathing training prescription, including:

Define a personalized deep breathing training prescription; the personalized deep breathing training prescription includes the following parameters: breathing training frequency, training duration, breathing frequency, ratio of inhalation to exhalation time, and breathing type;

Guide the subject to carry out the cardiopulmonary harmony test: when the subject is in a resting state, guide the subject to breathe for the first preset duration at free breathing and multiple guided breathing frequencies, and measure the subject’s ECG signal simultaneously And respiration signals, and calculate the cardiopulmonary harmony series indicators of the subject during free breathing and at different guided breathing frequencies according to the ECG signal and the breathing signal. The cardiopulmonary harmony series indicators include the cardiopulmonary harmony curve, the cardiopulmonary harmony degree, the cardiopulmonary resonance frequency, Cardiopulmonary resonance factor, cardiopulmonary harmony curve bandwidth and cardiopulmonary resonance quality factor;

Formulate a personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the best guided breathing frequency of the testee’s cardiopulmonary harmony series as the breathing frequency parameter of the breathing training, and the other parameters in the personalized deep breathing training prescription correspond to The value is the default value; among them, the default values and selection principles of other parameters of the personalized deep breathing training prescription are: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, breathing The training duration for people with difficulty is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, the default value of breathing type is lip-pull breathing, and those who have a basis in breathing training choose abdominal breathing;

According to the personalized deep breathing training prescription, the subjects are provided with voice, scene, music, and imagination guided breathing training.

The above scheme is based on the cardiopulmonary harmony test of free breathing and guided breathing to obtain the cardiopulmonary harmony series index CRI, and uses the cardiopulmonary harmony series index CRI as the key index, which can standardize the testee's cardiopulmonary harmony state, and then can formulate personality based on the evaluation results Intensify the deep breathing training prescription, guide and monitor the subjects' deep breathing training.

Optionally, the method further includes:

After the subject has performed the second preset duration of breathing training according to the personalized deep breathing training prescription, taking the breathing frequency in the personalized deep breathing training prescription as a reference, take at least one test breathing frequency within a preset range that fluctuates up and down;

According to the at least one test breathing rate, the testee is again guided to carry out the cardiopulmonary harmony test: when the testee is in a resting state, the testee is guided to breathe at different test breathing rates, and the testee’s ECG is measured simultaneously Signal and respiration signal, according to the ECG signal and respiration signal, calculate a series of indicators of the testee’s cardiopulmonary harmony at different test breathing frequencies;

Formulate a new personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the test breathing frequency with the best test results for the testee’s cardiopulmonary harmony series as the respiratory frequency parameter of the breathing training. Others in the new personalized deep breathing training prescription The parameter value is the same as the parameter value of the original personalized deep breathing training prescription;

According to the new personalized deep breathing training prescription, the testee is guided to perform breathing training.

After a period of deep breathing training, after the subject’s respiratory system and physical conditions gradually become better, the subject can be guided again to carry out a cardiopulmonary harmony test, update the subject’s personalized deep breathing training prescription, and realize the continuous optimization and optimization of the prescription. Update.

In the second aspect, the embodiments of the present application provide a system for formulating and implementing personalized deep breathing training prescriptions, including: wearable devices, user evaluation devices, user training devices, servers, and doctor terminals;

The server is used to issue a cardiopulmonary harmony test instruction to the user evaluation equipment of the test subject, the cardiopulmonary harmony test instruction including the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing;

The user evaluation device is used to guide the subject to breathe freely for a first preset period of time based on the cardiopulmonary harmony test instruction when the subject is in a resting state, and to guide the subject to follow the cardiopulmonary harmony test after the free breathing is over The guided breathing frequency in the instruction is used for guided breathing;

The wearable device is used to synchronously collect the ECG and respiration signals of the subject during free breathing and at different guided breathing frequencies, and send them to the user evaluation device;

The user evaluation equipment is used to calculate the cardiopulmonary harmony series indicators of the subject during free breathing and different guided breathing frequencies based on the ECG signals and breathing signals collected by the wearable device, and send them to the server;

The server is used to select the optimal guided breathing frequency of the testee’s cardiopulmonary harmony series indicators from multiple cardiopulmonary harmony series indicators as the breathing frequency parameters for breathing training, and to formulate personalized deep breathing training prescription recommendations. Personalized deep breathing training prescription recommendations The corresponding values of the other parameters of, the default values of the other parameters in the personalized deep breathing training prescription suggestion and the selection principle are: the default value of the breathing training frequency is 1 time per day, and the training duration is lacking. The saving value is 20 minutes each time, the training duration for people with difficulty breathing is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, and the default value of breathing type is lip-pull breathing, with breathing The training basic person chooses abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestion to the doctor terminal;

The doctor terminal is used to receive the doctor’s approval and modification of the personalized deep breathing training prescription suggestion, and save the final personalized deep breathing training prescription to the case database on the server;

The user training equipment is used to obtain the individual's personalized deep breathing training prescription from the case database of the server, and provide the subject with voice, scene, music, and imagination-guided breathing training according to the personalized deep breathing training prescription.

Optionally, the server is further configured to: after the subject has performed breathing training for a second preset duration in accordance with the personalized deep breathing training prescription, use the breathing frequency in the personalized deep breathing training prescription as a reference, floating up and down. Taking at least one test breathing frequency within a preset range; and issuing a cardiopulmonary harmony test instruction to the user evaluation device of the subject again according to the at least one test breathing frequency;

The user evaluation device is also used to guide the testee to conduct guided breathing according to the test breathing frequency in the cardiopulmonary harmony test instruction when the test subject is in a resting state based on the cardiopulmonary harmony test instruction;

The wearable device is also used to synchronously collect the ECG signal and respiration signal of the subject at different test breathing frequencies, and send them to the user evaluation device;

The user evaluation equipment is also used to calculate the heart-lung harmony series indicators of the subject at different test breathing frequencies based on the ECG signals and respiratory signals collected by the wearable device, and send them to the server;

The server is also used to select the optimal test breathing rate of the testee’s cardiopulmonary harmony series of indicators from a number of cardiopulmonary harmony series indicators, as the breathing frequency parameter of the breathing training, and formulate new personalized deep breathing training prescription recommendations, new personalized The values of other parameters in the deep breathing training prescription suggestion are the same as those of the original personalized deep breathing training prescription; the server is also used to submit the new personalized deep breathing training prescription suggestion to the doctor terminal;

The doctor terminal is used to receive the doctor's approval and modification of the new personalized deep breathing training prescription suggestion, and update the final personalized deep breathing training prescription to the case database on the server.

Optionally, the server is also used to generate the testee’s evaluation report based on the series of indicators, heart rate variability, and breathing variability corresponding to the testee sent from the user’s evaluation device after the cardiopulmonary harmony test is over. The report lists the series of indicators of cardiopulmonary harmony, heart rate variability, and respiratory variability under free breathing and guided breathing rate in tabular form, and visualizes the series of indicators of cardiopulmonary harmony, heart rate variability, and respiratory variability in different breaths. The change between pattern and breathing rate.

In a third aspect, an embodiment of the present application provides a method for formulating and implementing a personalized deep breathing training prescription, which is applied to a server, and the method includes:

A cardiopulmonary harmony test instruction is issued to the user evaluation device of the subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, as well as the test duration of free breathing and guided breathing, so that the user evaluation device can guide the subject to carry out Cardiopulmonary harmony test;

Receive the testee’s cardiopulmonary harmony test results from the user evaluation device, select the optimal guided breathing frequency of the testee’s cardiopulmonary harmony series of indicators according to the test results of the cardiopulmonary harmony test, as the respiratory frequency parameter of the breathing training, and formulate personalized deep breathing training In the prescription suggestion, the values corresponding to other parameters in the personalized deep breathing training prescription suggestion are default values; wherein, the default values and selection principles of other parameters in the personalized deep breathing training prescription suggestion are: the default value of breathing training frequency It is 1 time per day, the default value of training duration is 20 minutes each time, the training duration of people with dyspnea is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, the lack of breathing type The saving value is reduced lip breathing, and those who have a basic breathing training can choose abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestion to the doctor terminal;

Receive the final personalized deep-breath training prescription obtained after the doctor’s approval and modification of the personalized deep-breath training prescription suggestion from the doctor’s terminal, and save it in the case database. The personalized deep-breath training prescription is used to provide information to the patient The examiner provides a variety of parameters for breathing training.

In a fourth aspect, an embodiment of the present application provides an apparatus for formulating and implementing a personalized deep breathing training prescription, which is configured on a server, and the apparatus includes:

The cardiopulmonary harmony test instruction issuing unit is used to issue a cardiopulmonary harmony test instruction to the user evaluation equipment of the test subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing. Use the user evaluation equipment to guide the testees to carry out the heart-lung harmony test;

The personalized deep breathing training prescription generation and management unit is used to receive the testee’s cardiopulmonary harmony test results from the user evaluation device, and select the testee’s cardiopulmonary harmony series index optimal guided breathing frequency according to the cardiopulmonary harmony test results, as the breath Training respiratory frequency parameters, and formulating personalized deep breathing training prescription recommendations, the corresponding values of other parameters in the personalized deep breathing training prescription recommendations are default values; wherein, the default values of other parameters in the personalized deep breathing training prescription recommendations And the selection principle is: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, the training duration for people with dyspnea is 5 minutes or 10 minutes each time, inhalation and exhalation time The default value of the ratio is 1.5, the default value of the breathing type is lip-pull breathing, and those who have a basic breathing training can choose abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestions to the doctor terminal;

The case database storage unit is used to receive the final personalized deep breathing training prescription obtained after the doctor’s approval and modification of the personalized deep breathing training prescription suggestion from the doctor’s terminal, and save it in the case database. The deep breathing training prescription is used to provide a variety of parameters of breathing training to the subjects.

Description of the drawings

In order to more clearly describe the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings that need to be used in the embodiments of the present application. It should be understood that the following drawings only show certain embodiments of the present application. Therefore, It should not be regarded as a limitation of the scope. For those of ordinary skill in the art, other relevant drawings can be obtained from these drawings without creative work.

Fig. 1 is a flowchart of a method for calculating a series of indicators of cardiopulmonary harmony provided by an embodiment of the application;

2 is a flowchart of a method for formulating and implementing a personalized deep breathing training prescription provided by an embodiment of the application;

FIG. 3 is another flowchart of a method for formulating and implementing a personalized deep breathing training prescription provided by an embodiment of the application;

Fig. 4 is a schematic diagram of a system for formulating and implementing a personalized deep breathing training prescription provided by an embodiment of the application;

FIG. 5 is a flowchart of a method for formulating and implementing a personalized deep breathing training prescription using the system in FIG. 4 as an example according to an embodiment of the application;

FIG. 6 is another flowchart of the formulation and implementation method of a personalized deep breathing training prescription using the system in FIG. 4 as an example according to an embodiment of the application;

FIG. 7 is a schematic diagram of a device for formulating and implementing a personalized deep breathing training prescription provided by an embodiment of the application.

Icon: 310-wearable device; 320-user evaluation equipment; 330-user training equipment; 340-server; 350-doctor terminal; 311-electrocardiogram electrode; 312-respiration sensor; 313-motion sensor.

Detailed ways

The technical solutions in the embodiments of the present application will be described below in conjunction with the drawings in the embodiments of the present application.

The embodiments of this application use Cardiopulmonary Resonance Indicators (CRI) as key indicators to establish a standardized method for evaluating the testee’s cardiopulmonary harmony state, which can then be used to formulate personalized deep breathing training prescriptions. The cardiopulmonary harmony series indicators quantitatively give the degree of cardiopulmonary harmony and the influence of physiological and psychological factors on cardiopulmonary harmony. Before introducing the formulation and implementation methods of personalized deep breathing training prescriptions in the embodiments of this application, the series of indicators of cardiopulmonary harmony The calculation method is introduced. Among them, the CRI of the cardiopulmonary harmony series indicators includes: cardiopulmonary harmony curve G(f), cardiopulmonary resonance Amplitude (CRA), cardiopulmonary resonance frequency, cardiopulmonary resonance factor (CRF), cardiopulmonary resonance curve bandwidth (Cardiopulmonary Resonance) Bandwidth, CRB) and Cardiopulmonary Resonance Quality factor (CRQ). The cardiopulmonary harmony curve is used to characterize the influence of respiration on different frequency points in the frequency domain of the modulation of the heartbeat RR interval sequence; the cardiopulmonary harmony is the maximum influence value in the cardiopulmonary harmony curve; the cardiopulmonary resonance frequency is the resonance frequency corresponding to the maximum influence value ; The cardiopulmonary resonance factor is the mean value of the square of the influence value; the cardiopulmonary resonance quality factor is the ratio of the cardiopulmonary resonance frequency to the bandwidth of the cardiopulmonary harmony curve.

Specifically, please refer to Figure 1. The calculation method of the Heart-Lung Harmony Series Index includes the following steps:

Step 110: Obtain the ECG signal and breathing signal of the subject.

The subject wears a wearable device. The wearable device is equipped with ECG electrodes, respiration sensors, and motion sensors. The wearable device uses the ECG electrodes, respiration sensors, and motion sensors to synchronously collect the testee’s ECG signals, respiration signals, and Exercise signal. The current state of the subject can be obtained through the exercise signal. When the subject is in a resting state, step 120 is performed on the ECG signal and breathing signal of the subject in the resting state.

Step 120: Extract the RR interval sequence from the ECG signal, and construct a binary regression mathematical model based on the RR interval sequence and the respiratory signal.

In the specific implementation process, because the ECG signal includes a variety of complexes, such as: P wave, QRS complex, T wave, RR interval and so on. Therefore, the RR interval sequence can be extracted from the ECG signal of the subject in a resting state, and a binary regression mathematical model can be constructed based on the RR interval sequence and the respiratory signal.

Optionally, after extracting the RR interval sequence, obtain abnormal points from the RR interval sequence, where the abnormal points can be determined by the following formula:

RRI _i is the sequence value of the i-th RR interval,

Is the average value of the RR interval series, RRI _i-1 is the value of the i-1th RR interval series, Std(RRI) is the standard deviation of the RR interval series, and i is a positive integer. Therefore, if the value of the i-th RR interval series does not satisfy the above formula, it indicates that the i-th RR interval series is an abnormal point.

After the abnormal points are obtained, the abnormal points are eliminated, and the eliminated abnormal points are interpolated by the cubic spline interpolation method to obtain the processed RR interval sequence. In step 120, the processed RR interval sequence can be based on the processed RR interval sequence. Construct a binary regression mathematical model.

Step 130: Transform the parameters in the binary regression mathematical model to the frequency domain to obtain a transformation matrix.

First, normalize the RR interval sequence and the respiratory signal respectively, and construct the following binary regression mathematical model according to the normalized RR interval sequence and the normalized respiratory signal:

Wherein, A _11,j , A _12,j , A _21,j and A _22,j are regression coefficients of a binary regression mathematical model; X ₁ is the RR interval sequence; X ₂ is the respiratory signal; ξ ₁ (t) and ξ ₂ (t) are regression residuals; p represents the length of the selected regression sequence, t represents the time at which the RR interval sequence or the respiratory signal is located, j is a positive integer, and 1≤j≤p.

Then, the parameters in the binary regression mathematical model are Fourier transformed to obtain the transformation matrix.

Specifically, after transforming the parameters in the binary regression mathematical model to the frequency domain, the following transformation matrix is obtained:

among them,

X ₁ (f) is the frequency domain representation of the RR interval sequence, X ₂ (f) is the frequency domain representation of the respiratory signal, E ₁ (f) and E ₂ (f) are the Fourier transforms of the regression residuals , I is a plural unit.

Step 140: Analyze the transformation matrix to obtain a series of indicators of cardiopulmonary harmony.

Using Granger causality analysis method to analyze the transformation matrix, obtain the influence value of respiration on different frequency points of the RR interval sequence in the frequency domain, and obtain the cardiopulmonary harmony curve G in the series of indicators of cardiopulmonary harmony according to the influence value of different frequency points (f).

Specifically, the above transformation matrix is analyzed by the following formula to obtain the influence value of respiration on different frequency points of the RR interval sequence in the frequency domain:

S(f)=<X(f)X ^* (f)>=<H(f)∑H ^* (f)>;

among them,

H(f) is the pair of matrix blocks

The result of the inversion; S(f) is obtained by matrix transformation of X(f);

G _y→x (f) is the influence value of respiration on different frequency points of the RR interval sequence in the frequency domain; x represents the RR interval sequence, and y represents the respiratory signal.

After the above analysis, the _{cardiopulmonary harmony curve G(f) can be obtained according to G y→x} (f); further, according to the cardiopulmonary harmony curve, the cardiopulmonary harmony degree CRA, the cardiopulmonary resonance frequency, the cardiopulmonary resonance factor CRF, and the bandwidth of the cardiopulmonary harmony curve can be obtained. CRB and cardiopulmonary resonance quality factor CRQ, where CRA=maxG(f), the frequency corresponding to CRA is the cardiopulmonary resonance frequency f _A , the cardiopulmonary resonance factor CRF=mean(G ² (f)), which is a measure of the resonance energy of the cardiopulmonary system , The cardiopulmonary resonance quality factor CRQ is a measure of the resonance characteristics of the cardiopulmonary system. It is the ratio of the cardiopulmonary resonance frequency f _A to the cardiopulmonary harmony curve G(f) when the value of the cardiopulmonary harmony curve G(f) drops to 0.707, that is: CRQ=f _A Δf. Through the above method, a series of indicators of cardiopulmonary harmony can be obtained.

Based on the CRI of the above-mentioned cardiopulmonary harmony series index, the embodiment of this application provides a method for formulating and implementing a personalized deep breathing training prescription, which can evaluate the testee's cardiopulmonary harmony state in a standardized manner, and formulate personalized deep breathing training based on the evaluation results Prescribe, guide and monitor the subjects’ deep breathing training. Figure 2 shows a flowchart of the method for formulating and implementing the personalized deep breathing training prescription. As shown in Figure 2, the method includes the following steps:

Step 210: Define a personalized deep breathing training prescription; the personalized deep breathing training prescription includes the following parameters: breathing training frequency, training duration, breathing frequency, ratio of inhalation to exhalation time, and breathing type.

Personalized Deep Breathing Training Prescription (Personalized Paced Breathing Exercise Prescription) includes but not limited to the following 5 parameters (TDFIT):

(1) Respiratory training frequency (Times per week or day), such as 1 or 2 times a day;

(2) Training duration (Duration), usually 10-30 minutes each time;

(3) Respiration frequency (Frequency), the frequency of adults when breathing freely is about 15-25 times per minute. The frequency of deep breathing varies from person to person. It can be taken, but not limited to, 15 times per minute (0.25 Hz), 12 times ( 0.2Hz), 9 times (0.15Hz), 6 times (0.1Hz), 5 times (0.083Hz).

(4) Inhalation-exhalation ratio (Inhalation-exhalation ratio), abbreviated as inhalation-exhalation ratio, commonly used inhalation-exhalation ratios include: 1, 1.5, 2, 2.5, etc.;

(5) Breathing type (Type). Free breathing is usually chest-abdominal breathing. The undulation and intensity of the chest and abdomen walls are basically the same when breathing. The breathing types for deep breathing are: A, Pursed Lip Breathing, using the nose Inhale and exhale, the mouth will shrink the lip to apply resistance, exhale slowly, and the shrinking lip will increase the ventilation volume and enhance the activity; B, abdominal breathing (diaphragmatic breathing), naturally let the abdomen bulge as much as possible when inhaling The lungs are filled, and the abdomen is naturally recessed when exhaling to achieve the goal of exhausting exhaust gas in the lungs.

Step 220: Instruct the subject to carry out the cardiopulmonary harmony test: when the subject is in a resting state, guide the subject to breathe for the first preset duration under free breathing and multiple guided breathing frequencies, and simultaneously measure the subject’s ECG signal and respiration signal, according to the ECG signal and respiration signal, calculate the series of indicators of cardiopulmonary harmony when the subject is breathing freely and when the breathing frequency is different.

In the cardiopulmonary harmony test, when the test subject performs the initial evaluation, the test subject is guided to breathe freely and to breathe. Human free breathing is generally called "shallow breathing", using only part of the lung volume. Deep breathing makes full use of lung volume, increases oxygen exchange, promotes cell activation, and enhances metabolic efficiency and parasympathetic vitality. During the test, the subject is guided to breathe freely for the first preset duration (such as 5 minutes), and after the free breath is over, the subject is guided to breathe according to multiple guided breathing frequencies (for example, according to each guided breathing, respectively). The frequency of deep breathing for 5 minutes one by one), the guided breathing rate is, for example: 15 times, 12 times, 9 times, and 6 times per minute. In order to simplify the test, it is also possible to take only one or two guided breathing rates. The inspiration-to-expiration ratio used when guiding breathing can be set to 1.5, and the breathing type is simple lip-reducing breathing.

While the subject is breathing freely and guided breathing, the subject’s ECG signal and breathing signal are measured simultaneously, and the subject’s heart and lungs during free breathing and at different guided breathing frequencies are calculated according to the calculation method provided above. Harmony series of indicators.

Step 230: Formulate a personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the best guided breathing frequency of the testee’s cardiopulmonary harmony series of indicators as the breathing frequency parameter of the breathing training, and others in the personalized deep breathing training prescription The corresponding value of the parameter is the default value.

The key to a personalized deep breathing training prescription is to select the breathing rate. In step 230, select the best guided breathing frequency of the testee’s cardiopulmonary harmony series of indicators from the multiple sets of cardiopulmonary harmony series indicators when the subject is at different guided breathing frequencies. Specifically, a set of cardiopulmonary harmony series indicators with the largest center-pulmonary harmony degree CRA and the smallest cardiopulmonary harmony curve bandwidth CRB can be selected to obtain the corresponding guided breathing frequency as the breathing frequency parameter of the personalized deep breathing training prescription. The corresponding values of other parameters in the personalized deep breathing training prescription are default values; among them, the default values and selection principles of other parameters of the personalized deep breathing training prescription are: the default value of the breathing training frequency is 1 time per day, and the training duration The default value of is 20 minutes each time. The training duration for people with dyspnea can be 5 minutes or 10 minutes each time, depending on their breathing ability (which can be evaluated by the cardiopulmonary harmony state) from short to long, and the ratio of inhalation to exhalation is The default value of is 1.5, and the default value of breathing type is lip-closed breathing. Those who have a basic breathing training can choose abdominal breathing.

Step 240: According to the personalized deep breathing training prescription, provide the testee with breathing training guided by voice, scene, music, and imagination.

The time of breathing training is chosen by the testee. After obtaining the individual's personalized deep breathing training prescription, the individual will be provided with voice, scene, music, and imagination-guided breathing training within the selected time according to the personalized deep breathing training prescription to realize training monitoring and guidance. Breathing training needs to vary from person to person in order to achieve good results. Therefore, generating personalized deep breathing training prescriptions based on the testee’s cardiopulmonary harmony series indicators is conducive to conditioning the testee through personalized intervention.

After the subject has performed the second preset duration of breathing training (such as one month) in accordance with the formulated personalized deep breathing training prescription, that is, after the subject’s cardiopulmonary harmony has been improved to a certain extent, the subject is given a second time Evaluation to update and optimize personalized deep breathing training prescriptions. As shown in Figure 3, the method also includes the following steps:

Step 250: Taking the breathing frequency in the personalized deep breathing training prescription as a reference, take at least one test breathing frequency within a preset range that fluctuates up and down.

Step 260: Re-guide the testee to carry out the cardiopulmonary harmony test according to at least one test breathing rate: When the testee is in a resting state, guide the testee to breathe according to different test breathing rates, and measure the testee's heart simultaneously. Electrical signal and breathing signal, according to the ECG signal and breathing signal, calculate the testee's heart-lung harmony series indicators at different test breathing frequencies.

Step 270: Formulate a new personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the test breathing frequency with the best test results of the testee’s cardiopulmonary harmony series as the respiratory frequency parameter of the breathing training, and a new personalized deep breathing training The values of other parameters in the prescription are the same as those of the original personalized deep breathing training prescription.

Step 280: Guide the subject to perform breathing training according to the new personalized deep breathing training prescription.

After breathing training for a period of time, the subjects were again guided to carry out the cardiopulmonary harmony test. In the previously formulated personalized deep breathing training prescription, 1-2 test breathing frequencies were selected from the upper and lower respiratory rates. The new test was found based on the results of the cardiopulmonary harmony test. Improve the breathing rate, and update personalized deep breathing training prescriptions. Other parameters in the newly formulated personalized deep-breath training prescription, such as the breathing-to-expiration ratio and breathing type, also take the breathing training parameters formulated during the initial evaluation.

FIG. 4 shows a schematic diagram of the formulation and implementation system of a personalized deep breathing training prescription in this embodiment. The system includes a wearable device 310, a user evaluation device 320, a user training device 330, a server 340, and a doctor terminal 350. Among them, the wearable device 310 is provided with an ECG electrode 311, a respiration sensor 312, and a motion sensor 313. The wearable device 310 uses the ECG electrode 311, the respiration sensor 312, and the motion sensor 313 to synchronously collect the subject’s ECG signal and respiration. Signal and motion signal, the wearable device 310 communicates with the user evaluation device 320, for example, Bluetooth connection, the wearable device 310 sends the ECG signal, respiration signal, and motion signal to the user evaluation device 320 through Bluetooth, and the user evaluation device 320 according to The ECG signal and breathing signal calculate the CRI of the cardiopulmonary harmony series indicators, and send the CRI to the server 340 via Ethernet, WIFI or GPRS. The server 340 formulates personalized deep breathing training prescription recommendations based on the CRI and submits them to the doctor terminal 350, the doctor The terminal 350 receives the doctor's approval and modification of the personalized deep breathing training prescription suggestion, and obtains the final personalized deep breathing training prescription. The user training device 330 realizes the guidance and monitoring of the breathing training by acquiring the individualized deep breathing training prescription of the testee. Among them, the user evaluation device 320 and the user training device 330 may both be smart phones, tablet computers, portable computers, and the like.

Fig. 5 takes the formulation and implementation system of the above-mentioned personalized deep breathing training prescription as an example, and specifically introduces the formulation and implementation method of the personalized deep breathing training prescription in this embodiment. As shown in Figure 5, the specific steps of the method are as follows:

Step 410: The server issues a cardiopulmonary harmony test instruction to the user evaluation device of the subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing.

The server issues a cardiopulmonary harmony test instruction to the user evaluation equipment to instruct the user evaluation equipment to guide the subject to carry out the cardiopulmonary harmony test. The cardiopulmonary harmony test instruction carries the test duration for the subject to breathe freely, the test duration for guided breathing, and the guidance The number and frequency of the breathing rate, for example, the test duration and frequency of the guided breathing include: 15 breaths, 12 breaths, 9 breaths, and 6 breaths per minute for 5 minutes.

Step 420: Based on the cardiopulmonary harmony test instruction, the user evaluation device guides the testee to breathe freely for the first preset length of time when the testee is in a resting state, and guides the testee to follow the cardiopulmonary harmony test after the free breathing is over. The guided breathing frequency in the command is used for guided breathing.

Step 430: The wearable device synchronously collects the ECG signal and the breathing signal of the subject during free breathing and different guided breathing frequencies, and sends them to the user evaluation device.

The user evaluation device receives the cardiopulmonary harmony test instruction issued by the server. The subject wears the wearable device, sits and calms down. When ready, activate the evaluation function key on the user evaluation device to perform the cardiopulmonary harmony test. The purpose of the cardiopulmonary harmony test is to evaluate the testee's cardiopulmonary harmony and to formulate a personalized deep breathing training prescription.

In the cardiopulmonary harmony test, the wearable device collects the testee’s ECG signal through the ECG electrodes, the respiration signal of the testee through the breathing sensor, and the motion signal of the testee (including the three-dimensional acceleration signal and the three-dimensional acceleration signal) through the motion sensor. Gyro signal), and send the ECG signal, respiration signal and exercise signal to the user evaluation device via Bluetooth. User evaluation equipment receives ECG signals, respiratory signals, and motion signals from wearable devices, processes ECG signals, and obtains heart rate data sequences; processes respiration signals to obtain respiratory data sequences; processes and analyzes three-dimensional acceleration signals and three-dimensional gyroscope signals, Obtain the subject's posture (sitting, lying, walking, running). The user evaluation device confirms the current state of the subject according to the motion signal from the wearable device, such as being in a resting state or a motion state. The resting state includes sitting and lying, and the motion state includes walking and running. When the user evaluation device confirms that the subject is in a resting state, the subject is guided to perform a cardiopulmonary harmony test.

It should be noted that in addition to determining the resting state of the subject through motion signals, it can also be determined in other ways, which is not specifically limited in the embodiment of the present application. In addition, the ECG signal and respiration signal of the wearable device can also be obtained through the PPG sensor. The PPG sensor is set at the fingertip of the subject to process the PPG signal measured by the PPG sensor to obtain the ECG signal and respiration signal.

Step 440: The user evaluation device calculates the cardiopulmonary harmony series indicators of the subject during free breathing and different guided breathing frequencies according to the ECG signal and the breathing signal collected by the wearable device, and sends them to the server.

The user evaluation device receives the ECG signal and breathing signal measured by the subject while breathing freely, as well as the ECG signal and breathing signal measured by the subject under different guided breathing frequencies. For example, when the subject is instructed to breathe according to the breathing rate: 15 times, 12 times, 9 times and 6 times per minute for 5 minutes each, then the user evaluation device will obtain a total of five sets of ECG signals and breathing signals, and then separately Five sets of ECG signals and respiratory signals are processed, and five sets of CRI of cardiopulmonary harmony series indicators are obtained by calculation. Optionally, in step 440, heart rate variability (HRV) and respiratory variability (Respiratory Rate Variability, RRV) of the subject can also be calculated at the same time. Among them, the calculation method of the cardiopulmonary harmony series indicators can refer to the above introduction, and the calculation method of the heart rate variability HRV and the respiratory variability RRV can refer to the existing technology, which will not be repeated here.

Step 450: The server selects the optimal guided breathing frequency of the testee's cardiopulmonary harmony series indicators from the multiple cardiopulmonary harmony series indicators as the breathing frequency parameters of the breathing training, and formulates personalized deep breathing training prescription recommendations and personalized deep breathing training prescription recommendations The other parameters in the corresponding values are the default values, and the personalized deep breathing training prescription suggestions are submitted to the doctor's terminal.

In the cardiopulmonary harmony series index CRI, the cardiopulmonary harmony represents the maximum depth of the coupling resonance of the cardiopulmonary system under the current measurement state, and reflects the degree of the testee's cardiopulmonary coupling. The greater the cardiopulmonary harmony, the current harmony state of the testee The better. The cardiopulmonary resonance factor expresses the coupling state of the heart and lungs at the energy level. The higher the cardiopulmonary resonance factor CRF, the greater the modulation of the heart by the respiratory system, and the better the resonance state of the heart and lungs. In addition, the cardiopulmonary resonance quality factor CRQ is high, and the cardiopulmonary harmony curve bandwidth Δf is narrow, indicating that the cardiopulmonary metabolism system is highly efficient. In this embodiment, the cardiopulmonary harmony state of the testee is evaluated according to the above-mentioned cardiopulmonary harmony series indicators, and personalized deep breathing training prescription recommendations are formulated according to the evaluation results.

Specifically, the server selects a set of cardiopulmonary harmony series indicators with the largest cardiopulmonary harmony degree CRA and the cardiopulmonary harmony curve bandwidth CRB from multiple sets of cardiopulmonary harmony series indicators, and obtains the corresponding guided breathing frequency as the breathing frequency parameter of the personalized deep breathing training prescription . The values of other parameters in the personalized deep breathing training prescription suggestion are the default values, for example: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, the ratio of inhalation to exhalation time The default value of is 1.5, and the default value of breath type is lip-pull breath.

Optionally, after the end of the cardiopulmonary harmony test, that is, after the server receives CRI, HRV, and RRV, it also generates and provides the testee's evaluation report at the same time. The evaluation report lists the series of indicators of cardiopulmonary harmony, heart rate variability and respiratory variability under free breathing and guided breathing rate in a table form, and graphically visualizes the series of indicators of cardiopulmonary harmony, heart rate variability and respiratory variability. The change between breathing pattern and breathing rate. The server submits the generated personalized deep breathing training prescription recommendations and the cardiopulmonary harmony test data CRI, HRV, and RRV to the doctor's terminal in the form of graphics and data.

Step 460: The doctor terminal receives the doctor's approval and modification of the personalized deep breathing training prescription suggestion, and saves the final personalized deep breathing training prescription to the case database on the server.

The doctor’s terminal communicates with the server. The doctor uses the doctor’s terminal to review the rationality of the personalized deep-breath training prescription recommendations, modify and approve the personalized deep-breath training prescription recommendations, and the doctor’s terminal saves the final personalized deep-breath training prescription obtained after the modification to the server. The server stores the cardiopulmonary harmony test data, personalized deep breathing training prescriptions and personal files of each subject in the case database. The doctor can read the testee's cardiopulmonary harmony test data, personalized deep breathing training prescription and personal files from the server through the doctor terminal, and display it on the doctor terminal.

Step 470: The user training device obtains the individual's personalized deep breathing training prescription from the case database of the server, and provides the subject with voice, scene, music, and imagination-guided breathing training according to the personalized deep breathing training prescription.

As the subjects perform deep breathing training according to personalized deep breathing training prescriptions, the subject’s respiratory system and physical conditions will gradually improve, gradually, and finally achieve the best cardiopulmonary harmony. After a period of deep breathing training, after the subject’s respiratory system and physical condition gradually improve, the subject can be guided again to carry out the cardiopulmonary harmony test. In the retest, only guided breathing can be performed instead of free breathing. .

Specifically, please refer to Figure 6. The formulation and implementation method of personalized deep breathing training prescription also includes the following steps:

Step 510: The server takes at least one test within a preset range that fluctuates up and down based on the breathing frequency in the personalized deep breathing training prescription after the subject has performed the second preset duration of breathing training according to the personalized deep breathing training prescription Respiration rate: according to the at least one test respiration rate, a cardiopulmonary harmony test instruction is issued to the user evaluation device of the subject again.

Step 520: Based on the cardiopulmonary harmony test instruction, the user evaluation device guides the testee to conduct guided breathing according to the test breathing frequency in the cardiopulmonary harmony test instruction when the subject is in a resting state.

Step 530: The wearable device synchronously collects the ECG signal and the breathing signal of the subject at different test breathing frequencies, and sends them to the user evaluation device.

Step 540: The user evaluation device calculates a series of indicators of cardiopulmonary harmony of the testee at different test breathing frequencies according to the ECG signal and the breathing signal collected by the wearable device, and sends it to the server.

Step 550: The server selects the optimal test breathing rate of the testee’s cardiopulmonary harmony series indicators from the multiple cardiopulmonary harmony series indicators as the breathing frequency parameter of the breathing training, and formulates new personalized deep breathing training prescription recommendations, new personalization The values of other parameters in the deep breathing training prescription suggestion are the same as those of the original personalized deep breathing training prescription; and submit the new personalized deep breathing training prescription suggestion to the doctor terminal.

Step 560: The doctor terminal receives the doctor's approval and modification of the new personalized deep breathing training prescription suggestion, and updates the final personalized deep breathing training prescription to the case database on the server.

The above steps 510-560 complete the optimization and update of the individual's personalized deep breathing training prescription.

In a specific embodiment, during the user's deep breathing training phase, the user wears a wearable device, and the user training device obtains the user's personalized deep breathing training prescription through the APP, and according to the definition of the prescription, the user is reminded to start deep breathing training regularly. The wearable device and the user training device complete the Bluetooth connection. When ready, the subject starts the deep breath start button. The user training device informs the user of the parameters of the deep breathing training prescription in the form of language and/or subtitles. At the same time, it generates a language reminder based on the breathing frequency and inhalation ratio given by the deep breathing training prescription, with background music selected by the user. Guide users to perform deep breathing training with prescribed respiratory rate, inhalation-exhalation ratio, and breathing type. At the same time, the user training device receives the ECG signal and respiratory signal from the wearable device, calculates and uploads the cardiopulmonary harmony series indicators CRI, heart rate variability HRV and respiratory variability RRV. The user training device chooses to display the cardiopulmonary harmony CRA and/or the generated 100-point cardiopulmonary harmony score in the form of curves and graphics, and gives the user real-time effect feedback. The deep breathing training stops after the training time specified in the deep breathing training prescription ends, or when the user requests to stop.

After a deep breathing training is completed, the user's training device will generate a brief training report, including a personalized deep breathing training prescription and a 100-point cardiopulmonary harmony score change throughout the training process.

The server receives the training data from the user's training equipment and generates a professional training report. The training report contains the change curve of CRI, HRV, and RRV during the training process, the training execution status in the past week and one month, and each CRI, HRV, and RRV Changes in indicators.

In this embodiment, the server may be a cloud server, and a case database and a management system are deployed on the server. The doctor terminal can be implemented as a fixed terminal and a mobile terminal. The fixed terminal has user registration, management, cardiopulmonary harmony test organization and process monitoring, personalized deep breathing training monitoring, data analysis and research and other functions. The mobile terminal provides all or part of them. Features.

Wearable devices can take the following two forms: one is a miniature wearable device, which is attached to the chest, and two ECG electrodes are placed at two points about 10 cm apart from the upper and lower sides of the breast line, across the heart and lungs, in order to obtain A relatively clear electrocardiogram, and the principle of measuring changes in chest impedance to obtain high-quality respiratory signals. At the same time, because it is fixed at the chest position, the collected motion signals reflect the position of the human body's torso well and are used to classify postures. The other is a PPG signal collector clipped to the fingertips. The PPG signal collector is equipped with a PPG sensor for measuring PPG signals. ECG signals and respiratory signals can be extracted from the PPG signals.

Mini wearable devices, user evaluation equipment, and user training equipment form a cardiopulmonary harmony test client. The cardiopulmonary harmony test client, server, and doctor terminal jointly complete the cardiopulmonary harmony test, evaluate the user's cardiopulmonary harmony state, and formulate and generate personalized deep breathing training prescriptions .

Based on the same inventive concept, this embodiment provides a device for formulating and implementing a personalized deep breathing training prescription. The device is configured on a server. Please refer to FIG. 7. The device includes:

The cardiopulmonary harmony test instruction issuing unit 610 is used to issue a cardiopulmonary harmony test instruction to the user evaluation equipment of the test subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing, In order to enable the user evaluation equipment to guide the testees to carry out the cardiopulmonary harmony test;

The personalized deep breathing training prescription generation and management unit 620 is used to receive the testee’s cardiopulmonary harmony test results from the user evaluation device, and select the testee’s cardiopulmonary harmony series index optimal guided breathing frequency according to the cardiopulmonary harmony test results, as Respiratory frequency parameters of breathing training, and formulate personalized deep breathing training prescription recommendations, and the corresponding values of other parameters in the personalized deep breathing training prescription recommendations are default values; wherein, the default values of other parameters in the personalized deep breathing training prescription recommendations The value and selection principle are: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, and the training duration for people with dyspnea is 5 minutes or 10 minutes each time, inhale and exhale The default value of the time ratio is 1.5, and the default value of the breathing type is lip-pull breathing, and those who have a basic breathing training can choose abdominal breathing; the server is also used to submit the personalized deep breathing training prescription recommendations to the doctor terminal;

The case database storage unit 630 is configured to receive the final personalized deep breathing training prescription obtained after the doctor’s approval and modification of the personalized deep breathing training prescription suggestion from the doctor’s terminal, and save it in the case database. The deep breathing training prescription is used to provide the subjects with various parameters of breathing training.

Optionally, the cardiopulmonary harmony test instruction issuing unit 610 is also used to, after the subject has performed the second preset duration of breathing training according to the personalized deep breathing training prescription, based on the breathing frequency in the personalized deep breathing training prescription, Take at least one test breathing frequency within a preset range that fluctuates up and down; and issue a cardiopulmonary harmony test instruction to the user evaluation device of the subject again according to the at least one test breathing frequency;

The personalized deep breathing training prescription generation and management unit 620 is also used to select the optimal test breathing frequency of the testee’s cardiopulmonary harmony series indicators from the multiple cardiopulmonary harmony series indicators sent by the user evaluation device as the breathing frequency parameter of the breathing training , And formulate a new personalized deep breathing training prescription suggestion. The values of other parameters in the new personalized deep breathing training prescription suggestion are the same as those of the original personalized deep breathing training prescription; and submit the new personalized deep breathing training prescription suggestion to Doctor terminal

The case database storage unit 630 is also used to receive the final personalized deep breathing training prescription obtained after the doctor’s approval and modification of the new personalized deep breathing training prescription proposal sent by the doctor’s terminal, and to update the personality in the case database Intensify deep breathing training prescription.

The device for formulating and implementing personalized deep breathing training prescriptions provided above has the same basic principles and technical effects as the method executed on the server side in the previous method embodiment. For a brief description, the parts not mentioned in this embodiment can be Refer to the corresponding content in the foregoing method embodiment, which will not be repeated here.

In summary, the method, system and device for formulating and implementing a personalized deep breathing training prescription provided by the embodiments of the present application are based on the cardiopulmonary harmony test of free breathing and guided breathing to obtain the cardiopulmonary harmony series index CRI, and use the cardiopulmonary harmony series The indicator CRI is a key indicator, which can standardize the evaluation of the testee’s cardiopulmonary harmony, and then can formulate personalized deep breathing training prescriptions based on the evaluation results, guide and monitor the testee’s deep breathing training, which can solve the lack of science in the existing technology. Evaluation technology lacks personalized breathing training prescriptions, lack of basis and methods for formulating personalized breathing training prescriptions, and lack of a training system that implements breathing training guidance based on prescriptions, and continuously evaluates and optimizes.

In the embodiments provided in this application, it should be understood that the disclosed device and method may be implemented in other ways. The device embodiments described above are merely illustrative. For example, the division of the units is only a logical function division, and there may be other divisions in actual implementation. For example, multiple units or components may be combined or It can be integrated into another system, or some features can be ignored or not implemented. In addition, the displayed or discussed mutual coupling or direct coupling or communication connection may be through some communication interfaces, indirect coupling or communication connection of devices or units, and may be in electrical, mechanical or other forms.

Furthermore, the functional modules in the various embodiments of the present application may be integrated together to form an independent part, or each module may exist alone, or two or more modules may be integrated to form an independent part.

It should be noted that if the function is implemented in the form of a software function module and sold or used as an independent product, it can be stored in a computer readable storage medium. Based on this understanding, the technical solution of the present application essentially or the part that contributes to the existing technology or the part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a storage medium, including Several instructions are used to make a computer device (which may be a personal computer, a server, or a network device, etc.) execute all or part of the steps of the methods described in the various embodiments of the present application. The aforementioned storage media include: U disk, mobile hard disk, read-only memory (Read-Only Memory, ROM) random access memory (RAM), magnetic disk or optical disk and other media that can store program codes.

In this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such existence between these entities or operations. The actual relationship or order.

The above descriptions are only examples of the present application, and are not used to limit the protection scope of the present application. For those skilled in the art, the present application may have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of this application shall be included in the protection scope of this application.

Claims

A method for formulating and implementing a personalized deep breathing training prescription, which is characterized in that it includes:

Define a personalized deep breathing training prescription; the personalized deep breathing training prescription includes the following parameters: breathing training frequency, training duration, breathing frequency, ratio of inhalation to exhalation time, and breathing type;

Guide the subject to carry out the cardiopulmonary harmony test: when the subject is in a resting state, guide the subject to breathe for the first preset duration at free breathing and multiple guided breathing frequencies, and measure the subject’s ECG signal simultaneously And respiration signals, and calculate the cardiopulmonary harmony series indicators of the subject during free breathing and at different guided breathing frequencies according to the ECG signal and the breathing signal. The cardiopulmonary harmony series indicators include the cardiopulmonary harmony curve, the cardiopulmonary harmony degree, the cardiopulmonary resonance frequency, Cardiopulmonary resonance factor, cardiopulmonary harmony curve bandwidth and cardiopulmonary resonance quality factor;

Formulate a personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the best guided breathing frequency of the testee’s cardiopulmonary harmony series as the breathing frequency parameter of the breathing training, and the other parameters in the personalized deep breathing training prescription correspond to The value is the default value; among them, the default values and selection principles of other parameters of the personalized deep breathing training prescription are: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, breathing The training duration for people with difficulty is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, the default value of breathing type is lip-pull breathing, and those who have a basis in breathing training choose abdominal breathing;

According to the personalized deep breathing training prescription, the subjects are provided with voice, scene, music, and imagination guided breathing training.
The method according to claim 1, wherein the method further comprises:

After the subject has performed the second preset duration of breathing training according to the personalized deep breathing training prescription, taking the breathing frequency in the personalized deep breathing training prescription as a reference, take at least one test breathing frequency within a preset range that fluctuates up and down;

According to the at least one test breathing rate, the testee is guided again to carry out the cardiopulmonary harmony test: When the testee is in a resting state, the testee is guided to breathe at different test breathing rates, and the testee’s ECG is measured simultaneously Signal and respiration signal, according to the ECG signal and respiration signal, calculate a series of indicators of the testee’s heart and lung harmony at different test breathing frequencies;

Formulate a new personalized deep breathing training prescription based on the testee’s cardiopulmonary harmony test results: select the test breathing frequency with the best test results for the testee’s cardiopulmonary harmony series as the respiratory frequency parameter of the breathing training. Others in the new personalized deep breathing training prescription The parameter value is the same as the parameter value of the original personalized deep breathing training prescription;

According to the new personalized deep breathing training prescription, the testee is guided to perform breathing training.
A system for formulating and implementing personalized deep breathing training prescriptions, which is characterized by including: wearable equipment, user evaluation equipment, user training equipment, server and doctor terminal;

The server is used to issue a cardiopulmonary harmony test instruction to the user evaluation equipment of the test subject, the cardiopulmonary harmony test instruction including the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing;

The user evaluation device is used to guide the subject to breathe freely for a first preset period of time based on the cardiopulmonary harmony test instruction when the subject is in a resting state, and to guide the subject to follow the cardiopulmonary harmony test after the free breathing is over The guided breathing frequency in the instruction is used for guided breathing;

The wearable device is used to synchronously collect the ECG and respiration signals of the subject during free breathing and at different guided breathing frequencies, and send them to the user evaluation device;

The user evaluation equipment is used to calculate the cardiopulmonary harmony series indicators of the subject during free breathing and different guided breathing frequencies based on the ECG signals and breathing signals collected by the wearable device, and send them to the server;

The server is used to select the optimal guided breathing frequency of the testee’s cardiopulmonary harmony series indicators from multiple cardiopulmonary harmony series indicators as the breathing frequency parameters for breathing training, and to formulate personalized deep breathing training prescription recommendations. Personalized deep breathing training prescription recommendations The corresponding values of the other parameters of, the default values of the other parameters in the personalized deep breathing training prescription suggestion and the selection principle are: the default value of the breathing training frequency is 1 time per day, and the training duration is lacking. The saving value is 20 minutes each time, the training duration for people with difficulty breathing is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, and the default value of breathing type is lip-pull breathing, with breathing The training basic person chooses abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestion to the doctor terminal;

The doctor terminal is used to receive the doctor’s approval and modification of the personalized deep breathing training prescription suggestion, and save the final personalized deep breathing training prescription to the case database on the server;

The user training equipment is used to obtain the individual's personalized deep breathing training prescription from the case database of the server, and provide the subject with voice, scene, music, and imagination-guided breathing training according to the personalized deep breathing training prescription.
The system according to claim 3, wherein the server is further configured to: after the subject has performed breathing training for a second preset duration in accordance with the personalized deep breathing training prescription, use the personalized deep breathing training prescription Taking the respiratory frequency as a reference, taking at least one test respiratory frequency within a preset range that fluctuates up and down; according to the at least one test respiratory frequency, again issuing a cardiopulmonary harmony test instruction to the user evaluation device of the subject;

The user evaluation device is also used to guide the testee to conduct guided breathing according to the test breathing frequency in the cardiopulmonary harmony test instruction when the test subject is in a resting state based on the cardiopulmonary harmony test instruction;

The wearable device is also used to synchronously collect the ECG signal and respiration signal of the subject at different test breathing frequencies, and send them to the user evaluation device;

The user evaluation equipment is also used to calculate the heart-lung harmony series indicators of the subject at different test breathing frequencies based on the ECG signals and respiratory signals collected by the wearable device, and send them to the server;

The server is also used to select the optimal test breathing rate of the testee’s cardiopulmonary harmony series of indicators from a number of cardiopulmonary harmony series indicators, as the breathing frequency parameter of the breathing training, and formulate new personalized deep breathing training prescription recommendations, new personalized The values of other parameters in the deep breathing training prescription suggestion are the same as those of the original personalized deep breathing training prescription; the server is also used to submit the new personalized deep breathing training prescription suggestion to the doctor terminal;

The doctor terminal is used to receive the doctor's approval and modification of the new personalized deep breathing training prescription suggestion, and update the final personalized deep breathing training prescription to the case database on the server.
The system according to claim 3, wherein the server is further configured to, after the end of the cardiopulmonary harmony test, according to the series of indicators of cardiopulmonary harmony, heart rate variability and respiratory variability corresponding to the testee sent by the user evaluation device, The evaluation report of the testee is generated. The evaluation report lists the series of indicators of cardiopulmonary harmony, heart rate variability, and respiratory variability under free breathing and guided breathing rate in a table form, and displays the series of indicators of cardiopulmonary harmony and heart rate variability in a graphical visual manner The changes of sexual and respiratory variability among different breathing methods and respiratory frequencies.
A method for formulating and implementing a personalized deep breathing training prescription, which is characterized in that it is applied to a server, and the method includes:

A cardiopulmonary harmony test instruction is issued to the user evaluation device of the subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, as well as the test duration of free breathing and guided breathing, so that the user evaluation device can guide the subject to carry out Cardiopulmonary harmony test;

Receive the testee’s cardiopulmonary harmony test results from the user evaluation device, select the optimal guided breathing frequency of the testee’s cardiopulmonary harmony series of indicators according to the test results of the cardiopulmonary harmony test, as the respiratory frequency parameter of the breathing training, and formulate personalized deep breathing training In the prescription suggestion, the values corresponding to other parameters in the personalized deep breathing training prescription suggestion are default values; wherein, the default values and selection principles of other parameters in the personalized deep breathing training prescription suggestion are: the default value of breathing training frequency It is 1 time per day, the default value of training duration is 20 minutes each time, the training duration of people with dyspnea is 5 minutes or 10 minutes each time, the default value of the ratio of inhalation to exhalation time is 1.5, the lack of breathing type The saving value is reduced lip breathing, and those who have a basic breathing training can choose abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestion to the doctor terminal;

Receive the final personalized deep-breath training prescription obtained after the doctor’s approval and modification of the personalized deep-breath training prescription suggestion from the doctor’s terminal, and save it in the case database. The personalized deep-breath training prescription is used to inform the patient The tester provides a variety of parameters for breathing training.
A device for formulating and implementing personalized deep breathing training prescriptions is characterized in that it is configured on a server, and the device includes:

The cardiopulmonary harmony test instruction issuing unit is used to issue a cardiopulmonary harmony test instruction to the user evaluation equipment of the test subject. The cardiopulmonary harmony test instruction includes the number and frequency of the guided breathing rate, and the test duration of free breathing and guided breathing. Use the user evaluation equipment to guide the testees to carry out the heart-lung harmony test;

The personalized deep breathing training prescription generation and management unit is used to receive the testee’s cardiopulmonary harmony test results from the user evaluation device, and select the testee’s cardiopulmonary harmony series index optimal guided breathing frequency according to the cardiopulmonary harmony test results, as the breath Training respiratory frequency parameters, and formulating personalized deep breathing training prescription recommendations, the corresponding values of other parameters in the personalized deep breathing training prescription recommendations are default values; wherein, the default values of other parameters in the personalized deep breathing training prescription recommendations And the selection principle is: the default value of breathing training frequency is 1 time per day, the default value of training duration is 20 minutes each time, the training duration for people with dyspnea is 5 minutes or 10 minutes each time, inhalation and exhalation time The default value of the ratio is 1.5, the default value of the breathing type is lip-pull breathing, and those who have a basic breathing training can choose abdominal breathing; the server is also used to submit the personalized deep breathing training prescription suggestions to the doctor terminal;

The case database storage unit is used to receive the final personalized deep breathing training prescription obtained after the doctor’s approval and modification of the personalized deep breathing training prescription suggestion from the doctor’s terminal, and save it in the case database. The deep breathing training prescription is used to provide a variety of parameters of breathing training to the subjects.