WO2021042242A1 - Ultrasonic imaging device and ultrasonic echo signal processing method thereof - Google Patents

Ultrasonic imaging device and ultrasonic echo signal processing method thereof Download PDF

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Publication number
WO2021042242A1
WO2021042242A1 PCT/CN2019/104026 CN2019104026W WO2021042242A1 WO 2021042242 A1 WO2021042242 A1 WO 2021042242A1 CN 2019104026 W CN2019104026 W CN 2019104026W WO 2021042242 A1 WO2021042242 A1 WO 2021042242A1
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Prior art keywords
quantitative value
credibility
liver
display
quantitative
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PCT/CN2019/104026
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French (fr)
Chinese (zh)
Inventor
李若平
安兴
丛龙飞
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深圳迈瑞生物医疗电子股份有限公司
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Priority to PCT/CN2019/104026 priority Critical patent/WO2021042242A1/en
Priority to CN201980097390.XA priority patent/CN113939236A/en
Publication of WO2021042242A1 publication Critical patent/WO2021042242A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/44Processing the detected response signal, e.g. electronic circuits specially adapted therefor

Definitions

  • the invention relates to the field of medical equipment, in particular to an ultrasonic imaging equipment and a processing method of ultrasonic echo signals.
  • the present invention mainly provides an ultrasonic imaging equipment and a processing method for ultrasonic echo signals thereof.
  • An embodiment provides an ultrasound imaging device, including:
  • An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
  • a transmitting/receiving control circuit for controlling the ultrasonic probe to transmit ultrasonic waves to a target area and receive echoes of the ultrasonic waves
  • Display used to output visual information
  • An embodiment provides an ultrasound imaging device, including:
  • An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
  • the transmitting/receiving control circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the target area and receive echoes of the ultrasonic waves;
  • Display used to output visual information
  • the quantitative value and the credibility are displayed on the display interface of the display.
  • An embodiment provides a method for processing ultrasonic echo signals, including:
  • the degree of interest in the image of interest is displayed in association on the display interface.
  • the quantitative value and the credibility can be visually displayed on the display interface of the display.
  • FIG. 1 is a structural block diagram of an ultrasonic imaging device provided by an embodiment of the present invention
  • FIG. 2 is a flowchart of a method for processing ultrasonic echo signals according to an embodiment of the present invention
  • Fig. 3 is a flowchart of the method of step 2 in Fig. 2;
  • FIG. 4 is a schematic diagram of graphically displaying quantitative values and their credibility on an ultrasound image in an embodiment of the present invention
  • Fig. 5a is a schematic diagram of a first graph with low reliability in an embodiment of the present invention.
  • FIG. 5b is a schematic diagram of a first graph of medium reliability in an embodiment of the present invention.
  • FIG. 5c is a schematic diagram of a first graphic with high reliability in an embodiment of the present invention.
  • Fig. 6 is a schematic diagram of a first graph combining coordinates and graphs in an embodiment of the present invention.
  • FIG. 7 is a schematic diagram of a first graph showing credibility in text in an embodiment of the present invention.
  • Fig. 8a is a schematic diagram showing quantitative values and their credibility in a rectangular chart in an embodiment of the present invention.
  • Fig. 8b is a schematic diagram showing quantitative values and their credibility in a triangular chart in an embodiment of the present invention.
  • FIG. 9 is a schematic diagram showing the combination of the first graph and the chart to display the quantitative value and its credibility in an embodiment of the present invention.
  • FIG. 10 is a schematic diagram of a first graph combining coordinates and graphs in an embodiment of the present invention.
  • FIG. 11 is a flowchart of an embodiment of step 2 in FIG. 2;
  • Figure 12 is a schematic diagram of a display interface in an embodiment of the present invention.
  • FIG. 13 is a flowchart of an embodiment of step 2 in FIG. 2.
  • connection and “connection” mentioned in this application include direct and indirect connection (connection) unless otherwise specified.
  • the ultrasonic imaging equipment provided by the present invention includes an ultrasonic probe 20, a transmitting/receiving circuit 30 (ie, a transmitting circuit 310 and a receiving circuit 320), a processor 40, a memory 50 and a human-computer interaction device.
  • the ultrasonic probe 20 includes a transducer (not shown in the figure) composed of a plurality of array elements arranged in an array, and the plurality of array elements are arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form a surface array.
  • the array elements can also form a convex array.
  • the array element is used to transmit an ultrasonic beam according to the excitation electrical signal, or to transform the received ultrasonic beam into an electrical signal. Therefore, each array element can be used to realize the mutual conversion of electrical pulse signals and ultrasonic beams, so as to realize the transmission of ultrasonic waves to the target area of human tissue (such as the liver in this embodiment), and it can also be used to receive the echo of the ultrasonic waves reflected by the tissue.
  • the transmitting circuit 310 and the receiving circuit 320 can control which array elements are used to transmit ultrasonic beams and which array elements are used to receive ultrasonic beams, or control the array elements to be used to transmit ultrasonic beams or receive ultrasonic beams in time slots. Echo.
  • the array elements participating in the ultrasonic transmission can be excited by electrical signals at the same time, thereby simultaneously emitting ultrasonic waves; or the array elements participating in the ultrasonic transmission can also be excited by several electrical signals with a certain time interval, so as to continuously emit ultrasonic waves with a certain time interval.
  • the user selects a suitable position and angle by moving the ultrasound probe 20 to transmit ultrasound to the liver 10 and receive the echo of the ultrasound returned from the liver 10, and obtain and output the electrical signal of the echo.
  • the electrical signal of the echo is According to the channel analog electrical signal formed by the receiving array element as the channel, it carries amplitude information, frequency information and time information.
  • the transmitting circuit 310 is used to generate a transmitting sequence according to the control of the transmitting/receiving sequence control module 410.
  • the transmitting sequence is used to control some or all of the multiple array elements to transmit ultrasonic waves to biological tissues.
  • the parameters of the transmitting sequence include the position of the transmitting array element, The number of array elements and ultrasonic beam emission parameters (such as amplitude, frequency, number of emission, emission interval, emission angle, wave type, focus position, etc.).
  • the transmitting circuit 310 is also used to phase delay the transmitted beams, so that different transmitting array elements emit ultrasonic waves at different times, so that each transmitted ultrasonic beam can be focused on a predetermined region of interest.
  • the transmission sequence parameters may be different.
  • the echo signal is received by the receiving circuit 320 and processed by subsequent modules and corresponding algorithms. Generate a B image that reflects the anatomical structure of the tissue, a C image that reflects the anatomical structure of the tissue and blood flow information, and a D image that reflects the Doppler spectrum image.
  • the receiving circuit 320 is used to receive the electrical signal of the ultrasonic echo from the ultrasonic probe 20 and process the electrical signal of the ultrasonic echo.
  • the receiving circuit 320 may include one or more amplifiers, analog-to-digital converters (ADC), and the like.
  • ADC analog-to-digital converters
  • the data output by the receiving circuit 320 may be output to the beam synthesis module 420 for processing, or output to the memory 50 for storage.
  • the processor 40 is used to configure a central controller circuit (CPU), one or more microprocessors, a graphics controller circuit (GPU) or any other electronic components that can process input data according to specific logic instructions. Commands or predetermined commands perform control of peripheral electronic components, or perform data reading and/or saving on the memory 50, and input data can also be processed by executing a program in the memory 50, for example, collecting data according to one or more working modes. Perform one or more processing operations on the ultrasound data.
  • CPU central controller circuit
  • microprocessors e.g., a graphics controller circuit (GPU) or any other electronic components that can process input data according to specific logic instructions.
  • GPU graphics controller circuit
  • the processing operations include, but are not limited to, adjusting or limiting the form of ultrasound emitted by the ultrasound probe 20, generating various image frames for subsequent display on the display 60 of the human-computer interaction device, or adjusting or Define the content and form displayed on the display 60, or adjust one or more image display settings displayed on the display 60 (for example, ultrasound images, interface components, locating regions of interest).
  • the processor 40 includes a transmission/reception sequence control module 410, a beam synthesis module 420, an IQ demodulation module 430, and an image processing module 440.
  • the beam synthesizing module 420 is connected to the receiving circuit 320 to signal the signal output by the receiving circuit 320. It is used to perform beam synthesizing processing such as delay and weighted summation on the signal output by the receiving circuit 320. Because the distance between the ultrasonic receiving point in the measured tissue and the receiving array element is different Therefore, the channel data of the same receiving point output by different receiving array elements has delay differences, and delay processing is required to align the phases, and the different channel data of the same receiving point are weighted and summed to obtain the beam-combined ultrasound Image data, the ultrasound image data output by the beam synthesis module 420 is also called radio frequency data (RF data).
  • the beam synthesis module 420 outputs the radio frequency data to the IQ demodulation module 430. In some embodiments, the beam combining module 420 may also output the radio frequency data to the memory 50 for buffering or storage, or directly output the radio frequency data to the image processing module 440 for image processing.
  • the IQ demodulation module 430 removes the signal carrier through IQ demodulation, extracts the organizational structure information contained in the signal, and performs filtering to remove noise. At this time, the acquired signal is called a baseband signal (IQ data pair).
  • the IQ demodulation module 430 outputs the IQ data pair to the image processing module 440 for image processing.
  • the IQ demodulation module 430 also buffers or saves the IQ data output to the memory 50, so that the image processing module 440 reads the data from the memory 50 for subsequent image processing.
  • the image processing module 440 is used to process the data output by the beam synthesis module 420 or the data output by the IQ demodulation module 430 to generate a grayscale image of signal strength changes within the scanning range, which reflects the internal anatomy of the tissue
  • the structure is called a B image.
  • the image processing module 440 can output the B image to the display 60 of the human-computer interaction device for display.
  • the human-computer interaction device is used for human-computer interaction, that is, receiving user input and outputting visual information; it can receive user input using keyboard, operation buttons, mouse, trackball, etc., or it can use touch integrated with the display Screen; its output visualized information adopts the display 60.
  • the memory 50 may be a flash memory card, a solid-state memory, a hard disk, and the like.
  • the processing method of the ultrasonic echo signal is shown in Fig. 2, including the following steps:
  • the processor 40 obtains the ultrasound echo signal of the liver.
  • the processor 40 may obtain the ultrasound echo signal of the liver from the memory 50 or an external device, or may use the ultrasound probe 20 to obtain it.
  • the ultrasound probe 20 is used as an example for description.
  • the transmitting/receiving sequence control module 410 controls the ultrasonic probe 20 through the transmitting/receiving control circuit 30 to transmit ultrasonic waves to the liver and receive the echoes of the ultrasonic waves to obtain the echoed electrical signals.
  • the processor 40 obtains an ultrasonic echo signal according to the echoed electrical signal.
  • the processing of the electrical signal obtained from the echo may include signal processing links such as analog signal gain compensation, beam synthesis, IQ demodulation, digital signal gain compensation, amplitude calculation, and image enhancement.
  • signal processing links such as analog signal gain compensation, beam synthesis, IQ demodulation, digital signal gain compensation, amplitude calculation, and image enhancement.
  • the above-mentioned electrical signal is subjected to front-end filtering and amplification (that is, gain compensation) through an analog circuit, and then converted into a digital signal by an analog-to-digital converter (ADC), and the channel data after the analog-to-digital conversion is further subjected to beam synthesis processing to form a scan line Data, the data processing performed before this can be collectively referred to as front-end processing.
  • ADC analog-to-digital converter
  • the data obtained after the completion of this stage may be referred to as radio frequency signal data, that is, RF data.
  • radio frequency signal data that is, RF data.
  • the signal carrier is removed by IQ demodulation, the organizational structure information contained in the signal is extracted, and filtering is performed to remove noise.
  • the acquired signal is a baseband signal (IQ data). All the processing required from the radio frequency signal processing to the baseband signal can be collectively referred to as mid-end processing.
  • mid-end processing All the processing required from the radio frequency signal processing to the baseband signal can be collectively referred to as mid-end processing.
  • the processing completed at this time can be collectively referred to as back-end processing.
  • the ultrasonic echo signal of the present invention is the data obtained by performing one-stage or multi-stage signal processing on the electrical signal obtained based on the ultrasonic echo, that is, the ultrasonic echo signal can be the data generated in any of the above-mentioned signal processing links.
  • the ultrasonic echo signal may be an analog or digital ultrasonic echo signal before beam synthesis, or data after beam synthesis, such as the ultrasonic echo signal output by the beam synthesis module 50, or it may be after IQ demodulation.
  • the data, such as the ultrasound echo signal output by the IQ demodulation module 60 may also be ultrasound image data obtained by further processing based on beam-synthesized data or IQ demodulated data.
  • the image processing module 440 analyzes the ultrasonic echo signal, identifies the image sign of interest contained therein, and obtains a quantitative value reflecting the degree of interest of the image sign of interest (image feature of interest) and the credibility of the quantitative value .
  • the image sign of interest is used to reflect the properties of the liver, such as whether the liver has disease, and the type of disease (fatty liver, liver fibrosis, tumor, etc.).
  • the image processing module 440 obtains a quantitative value reflecting the degree of interest of the image sign of interest and the credibility of the quantitative value according to the characteristics of the image of interest.
  • the degree of interest may be the severity of the disease. Or the severity of liver fibrosis as an example.
  • the ultrasonic echo signal may be the signal after the echoed electrical signal is beam-synthesized, and it may be the data output by the beam-synthesis module 420 or the data output by the IQ demodulation module 430. , It may also be the ultrasound image data processed by the image processing module 440.
  • the processor 40 analyzes the ultrasound echo signal to obtain a quantitative value of the severity of fatty liver or liver fibrosis and the credibility of the quantitative value, including: processing electrical signals to obtain an ultrasound image (gray image) The signal of any signal processing link is analyzed to obtain the quantitative value of the severity of fatty liver or liver fibrosis and the reliability of the quantitative value.
  • the image processing module 440 obtaining the quantitative value of the severity of fatty liver or liver fibrosis and the credibility of the quantitative value includes the following steps:
  • Step 210 The image processing module 440 automatically analyzes the ultrasound echo signal through a machine learning method to obtain a classification result of the severity of fatty liver or liver fibrosis and the probability of the classification result.
  • Machine learning can be traditional machine learning or deep learning. For example, obtain the ultrasound echo signals corresponding to livers with different severity of fatty liver or liver fibrosis; use ultrasound echo signals as input, and classify the severity of fatty liver or liver fibrosis as labels, perform machine learning or deep learning, and train Obtain the severity classification as a model function of the feature index; subsequently, input the ultrasound echo signal obtained by the image processing module 440 into the model function, and obtain the classification result and classification of the severity of the liver fatty liver or liver fibrosis corresponding to the ultrasound echo signal Probability of outcome.
  • the classification results include multiple categories, such as severe, moderate, minor, etc., and each category corresponds to a probability.
  • the probability of the classification result can be generated at the same time as the classification result is generated. This is a conventional method of machine learning. However, the prior art usually uses the most probable result as the final result, which is not the case in this application. This application uses probability to determine the severity For the second calculation, see step 220 for details.
  • Step 220 The image processing module 440 quantitatively calculates the severity of fatty liver or liver fibrosis according to the classification result and its probability, and obtains a quantitative value reflecting the severity of fatty liver or liver fibrosis.
  • the probability is used as the weight
  • at least two categories are weighted and calculated to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis.
  • Perform weight calculation on at least two categories may be performed on two or more categories with the highest probability among the classification results.
  • the classification results include severe, moderate, mild, and normal, which are represented as 3, 2, 1, 0 according to the grade.
  • the output analysis result is directly the classification result of the severity of the ultrasonic echo signal and the probability of the classification result.
  • the classification results and their probabilities obtained by the machine learning method are: severe (3), 60%, moderate (2), 20%, mild (1), 10%, normal (0), 10%; the final The quantitative value is: min(2,3)+
  • *(60%/(20%+60%))+0.5 3.25.
  • the quantitative interval corresponding to severe is 3-4
  • the quantitative interval corresponding to medium is 2-3
  • the quantitative interval corresponding to slight is 1-2
  • the quantitative interval corresponding to normal is 0-1.
  • the final severity of fatty liver or liver fibrosis of the patient lies within the severe quantitative interval, and the quantitative value is 3.25.
  • the severity obtained by this method is more accurate, and the numerical display further provides doctors with a more accurate reference, which is convenient for doctors to diagnose.
  • Step 230 The image processing module 440 calculates the credibility of the quantitative value according to the probability of the classification result. Specifically, the credibility is divided into multiple levels, each level corresponds to a probability interval, and the probability intervals add up to 1. For example, the probability intervals corresponding to high, medium, and low credibility are: : 100% ⁇ 70%, 70% ⁇ 30%, 30% ⁇ 0%.
  • the image processing module 440 calculates the credibility of the quantitative value according to the probability of the classification result (for example, n classification results).
  • the first two or n-1 numerical probabilities are added together to obtain
  • the value of the credibility preferably, the credibility of the quantitative value is calculated based on the probability used in the calculation of the quantitative value, for example, the probabilities used in the calculation of the quantitative value are added.
  • the image processing module 440 can also perform statistical analysis on the probability of at least the first two numerical values according to the magnitude of each probability, and determine that the relationship between the analysis result and the preset multiple credibility intervals (probability intervals) will be consistent.
  • the credibility corresponding to the preset credibility interval of is used as the credibility of the quantitative value.
  • This embodiment specifically takes the ultrasound echo signal as an ultrasound image as an example for description, where the ultrasound image may be a three-dimensional ultrasound image, an ultrasound B image, an ultrasound C image, etc., and this embodiment takes an ultrasound B image as an example for description.
  • the image processing module 440 can also automatically analyze the ultrasound image to obtain a reflection of fatty liver or liver.
  • the quantitative value of the severity of fibrosis for example, acquiring the texture parameter and the acoustic attenuation parameter of the ultrasound image, and determining the quantitative value according to the texture parameter and the acoustic attenuation parameter; and obtaining the credibility of the quantitative value according to the image quality of the ultrasound image degree. If the quality of the ultrasound image is poor, the quantitative value obtained by the automatic analysis is definitely low, and its credibility is also low, so that the credibility can be accurately obtained.
  • the image processing module 440 displays the calculated quantitative value and its credibility on the display interface of the display 50, and also displays the ultrasound image of the liver, as shown in FIG. 4, which is convenient for the doctor to observe the ultrasound image of the patient’s liver. , And understand the quantitative value and credibility of the severity of fatty liver or liver fibrosis.
  • the image processing module 440 may simultaneously display the quantitative value and the credibility on the display interface of the display 50; it may also display the quantitative value on the display interface of the display 50, and the human-computer interaction device receives the user After the preset instruction is input, the quantitative value and the credibility are displayed at the same time.
  • the simultaneous display of the quantitative value and its credibility is taken as an example for further description.
  • the image processing module 440 graphically displays the quantitative value and its credibility on the display interface of the display 50, and the graphical display is more intuitive. Specifically, the image processing module 440 takes the quantitative value as one dimension and the credibility as another dimension, and visually displays two-dimensional information on the display interface of the display 50. There are many kinds of two-dimensional information visualization display, which will be further explained by examples below.
  • the image processing module 440 provides a first graphic A.
  • the first graphic A may be obtained from a memory or an external device, or may be generated by the image processing module 440; on the display interface of the display 50
  • the first graph A is displayed, the quantitative value is identified by the quantitative index of the first graph A, and the credibility is identified by the qualitative index of the first graph.
  • the first image A can be various regular or irregular geometric figures, etc.
  • the first image A is a schematic diagram of the liver, which is convenient for visually showing the degree of fatty liver of the liver and its credibility.
  • the quantitative index includes the quantitative value and its range, and also includes at least one of the figure size, the filling area, and the number of filled tiles. As shown in FIG.
  • the quantitative index of the first figure A includes the filling area of the first image A ( The gray area in the figure), the quantitative value (2.4) and its range (0-4). The larger the filling area, the more serious the fatty liver. From a doctor's point of view, one can know that the severity of fatty liver or liver fibrosis is moderate at a glance, and the quantitative value is 2.4 (medium) by looking at the value, which is very convenient and intuitive.
  • the quantitative indicators can also use line segments to represent quantitative values, as shown in Figures 6 and 7.
  • Qualitative indicators include at least one of line color, filling color, filling pattern, filling block size, number of filling blocks, text, letters, and numbers; the filling color (gray) in Figure 5, the darker the gray indicates the credibility The higher the higher, Figures 5a-c show the low-reliability, medium-reliability, and high-reliability situations, which are also clear at a glance.
  • the qualitative index is the size of the filling block, supplemented by the coordinates, it can be seen that the credibility of the qualitative value in Fig. 6 is medium.
  • the image processing module 440 displays the first graphic A on the display interface of the display 50, uses the quantitative index of the first graphic A to mark the quantitative value, and marks the credibility on the first graphic A.
  • the credibility is directly displayed in the form of text, of course, the specific value of the credibility can be further displayed.
  • the image processing module 440 displays a chart for displaying the quantitative value and reliability on the display interface of the display 50, and the first coordinate axis of the chart is the quantitative value, and the first axis of the chart is the quantitative value.
  • the two axis is the credibility.
  • the chart can be a variety of geometric figures, and the coordinate axis is not limited to the conventional vertical coordinate axis.
  • the horizontal axis represents the quantitative value of the severity of fatty liver, the farther to the right the more serious the fatty liver; the vertical axis represents the reliability of the quantitative value of fatty liver, the higher the higher the reliability of the quantitative value,
  • the quantitative value in the figure is 2.8, and the reliability is medium.
  • the horizontal axis of the pyramid represents the quantitative value of fatty liver severity
  • the longitudinal axis represents the reliability of the quantitative value of fatty liver.
  • the pyramid from left to right represents the severity of fatty liver from normal to mild to moderate to severe. (Serious);
  • the pyramid from the bottom of the tower to the top of the tower represents the reliability of the quantitative value of fatty liver from low to high.
  • the quantitative value in the figure is 2.6, and the reliability is high.
  • the quantitative value of the geometric figure is used to identify the quantitative value
  • the qualitative indicator of the geometric figure is used to identify the quantitative value.
  • the credibility, the quantitative index and the qualitative index have been described in the above embodiments, and will not be repeated here.
  • the image processing module 440 displays the first graph A and the first coordinate axis D on the display interface of the display 50, so The qualitative index of the first graph A identifies the credibility, and the position of the first graph A corresponding to the first coordinate axis D identifies the quantitative value.
  • the first graph A and the first coordinate axis D can be connected by a straight line to facilitate the positioning of specific quantitative values on the coordinate axis; an arrow from the first graph A can also be used to indicate to the first coordinate axis D to facilitate the Position the specific quantitative value on the coordinate axis.
  • the first graph A has the above-mentioned qualitative index to identify the credibility.
  • Figure 6 is actually in this form, but the first coordinate axis is attached to the schematic diagram of the liver.
  • a second coordinate axis can also be set, and the second coordinate axis moves with the quantitative value.
  • the intersection of B and the second coordinate axis identifies the credibility.
  • the first coordinate axis and the second coordinate axis may also be set on adjacent two sides of the first image A, respectively.
  • the above embodiment describes the solution of displaying the quantitative value and its credibility at the same time.
  • the credibility is first hidden (not displayed), and the user-input preset is received in the human-computer interaction device.
  • the quantitative value and its credibility are displayed at the same time, that is, the hidden credibility is displayed.
  • the final effect is still shown in Figure 5 to Figure 10, so I will not repeat it.
  • the present invention aims at the severity of fatty liver or liver fibrosis.
  • the reliability of the quantitative value is calculated, and the quantitative value is summed up.
  • the reliability of these two parameters is combined with two-dimensional visual display, which provides doctors with accurate and comprehensive reference information and improves the accuracy of doctors' diagnosis.
  • the processor 40 processes the acquired ultrasonic echo data to obtain the texture parameter and the sound attenuation parameter of the liver 10, and determines the quantitative value of the severity of fatty liver or liver fibrosis of the liver 10 according to the texture parameter and the sound attenuation parameter .
  • the processor 40 processes the ultrasound image of the liver 10 to determine some related parameters of the liver 10 in the ultrasound image, for example, the texture parameters and sound attenuation parameters of the liver 10, etc.
  • the quantitative value of the severity of fatty liver or liver fibrosis of the liver 10 is determined according to the texture parameter and the acoustic attenuation parameter of the liver 10, so as to intuitively quantitatively analyze the severity of fatty liver or liver fibrosis.
  • the ultrasound image obtained by the processor 40 and related parameters of the liver 10 may be stored in the memory 50.
  • step 210' the processor 40 obtains the texture parameters and sound attenuation parameters of the ultrasound image.
  • the processor 40 After the processor 40 obtains the ultrasound image of the liver 10, it further obtains texture parameters and sound attenuation parameters in the ultrasound image. Among them, an optional implementation manner: determine the texture parameters of the ultrasound image according to the ultrasound image and a first preset model, where the first preset model is a model obtained by training based on historical data.
  • the process includes:
  • Step 2101 Obtain historical data.
  • the historical data includes analysis data of the severity of fatty liver or liver fibrosis of multiple livers.
  • the analysis data includes doctor diagnosis data of multiple livers and/or pathological diagnosis data of multiple livers.
  • the doctor's diagnosis data may include the diagnosis results of the multiple livers, such as the severity classification of fatty liver or liver fibrosis: normal, mild fatty liver, moderate fatty liver, severe fatty liver, etc.
  • the pathological diagnosis data may be data obtained through pathological analysis of the liver obtained by external surgery.
  • Step 2102 Establish the first preset model based on historical data.
  • the first preset model is obtained by training based on the historical data and preset algorithms, where the preset algorithm may include algorithms such as deep learning or machine learning.
  • the processor 40 may directly process the entire ultrasound image, that is, input the ultrasound image as an input parameter into the first preset model to obtain a feature image; and then perform texture characteristic analysis on the feature image , The texture parameters of the liver 10 are obtained.
  • the processor 40 inputs the ultrasound image as an input parameter into the first preset model to obtain the texture parameter of the liver 10.
  • the processor 40 determines the region to be analyzed in the ultrasound image, that is, the region of interest, where the region of interest may include the entire liver region or part of the liver region; and then the region to be analyzed The image of is input into the first preset model as an input parameter to obtain a characteristic image; then, texture characteristic analysis is performed on the characteristic image to obtain the texture parameter of the liver 10.
  • the processor 40 inputs the image of the region to be analyzed as an input parameter into the first preset model to obtain the texture parameter of the liver 10.
  • the acoustic attenuation parameter may be the ratio of the signal amplitude value of the ultrasonic echo at the first depth of the area to be analyzed to the signal amplitude value of the ultrasonic echo at the second depth of the area to be analyzed, where the first depth It can be the near field depth, the second depth can be the far field depth, or the first depth is the far field depth and the second depth is the near field depth, which is not specifically limited here.
  • the depth is the distance between the tissue in the area to be analyzed and the probe.
  • the sound attenuation parameter may be the ratio of the gray value corresponding to the image of the area to be analyzed at the first depth to the gray value of the image of the area to be analyzed at the second depth.
  • step 220' the processor 40 determines the fatty liver quantitative parameter of the liver 10 according to the texture parameter and the sound attenuation parameter.
  • the processor 40 determines the fatty liver quantitative parameter of the liver 10 according to the texture parameter and the sound attenuation parameter.
  • the processor determines the quantitative value of the liver 10 according to the texture parameter, the sound attenuation parameter, and the second preset model.
  • the second preset model may be a model trained according to algorithms such as deep learning or machine learning, and the texture parameter and the sound attenuation parameter are used as input to the second preset model to obtain the quantitative value of the liver 10 .
  • the second preset model may also be a functional relationship.
  • the functional relationship is a weight relationship, and the weight relationship includes a weight coefficient, and the weight coefficient may be system default or user-defined. There is no limit. For example, if the texture parameter is A, the sound attenuation parameter is B, and the weight coefficient is 4:6, the quantitative value is A*0.4+B*0.6.
  • the processor 40 may also average the texture parameter and the sound attenuation parameter to obtain the quantitative value of the liver 10, for example, the texture parameter is A, the sound attenuation parameter is B, that is, the weight coefficient is 1:1, Then the quantitative value is A*0.5+B*0.5.
  • the ultrasound image and the corresponding sound attenuation parameter and texture parameter are also displayed.
  • the ultrasound image 701 the regions to be analyzed 702 and 703 are displayed on the display; the region to be analyzed 702 is distinguished and displayed by means of shadow, color, or frame.
  • 703 is the quantitative value and Its credibility is shown in Figure 5 to Figure 10.
  • the processor 40 obtains the credibility of the quantitative value according to the image quality of the ultrasound image.
  • the image quality can be evaluated based on the overall brightness and artifacts of the ultrasound image.
  • the ultrasound image is matched with the preset standard image information library to obtain the matching degree with the standard image in the standard image information library; the matching degree reflects the image quality, and the higher the matching degree, the higher the image quality. The higher the credibility.
  • data other than the ultrasound image in the ultrasound echo data can also be used to calculate the quantitative value, for example, the quantitative value is calculated based on the data output by the receiving circuit 320, and the calculation is based on the data output by the beam synthesis module 420.
  • Quantitative value, or calculation of quantitative value based on the data output by IQ demodulation module 430 in other words, the above embodiment of calculating quantitative value based on ultrasound image can be extended to calculate quantitative value based on ultrasound echo data, the steps are shown in Figure 13 Shown. Since the specific process of calculating the quantitative value and its credibility based on the ultrasound echo data is the same as the above-mentioned calculation process based on the ultrasound image, it will not be repeated here.
  • the program may be stored in a computer-readable storage medium.
  • the storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc.
  • the computer executes the program to realize the above-mentioned functions.
  • the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized.
  • the program can also be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying.
  • a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying.
  • the program in the memory is executed by the processor, all or part of the functions in the foregoing embodiments can be realized.
  • the principles herein can be reflected in a computer program product on a computer-readable storage medium, which is pre-installed with computer-readable program code.
  • a computer-readable storage medium Any tangible, non-transitory computer-readable storage medium can be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROM, DVD, Blu Ray disks, etc.), flash memory and/or the like .
  • These computer program instructions can be loaded on a general-purpose computer, a special-purpose computer, or other programmable data processing equipment to form a machine, so that these instructions executed on the computer or other programmable data processing device can generate a device that realizes the specified function.
  • Computer program instructions can also be stored in a computer-readable memory, which can instruct a computer or other programmable data processing equipment to operate in a specific manner, so that the instructions stored in the computer-readable memory can form a piece of Manufactured products, including realizing devices that realize designated functions.
  • Computer program instructions can also be loaded on a computer or other programmable data processing equipment, thereby executing a series of operation steps on the computer or other programmable equipment to produce a computer-implemented process, so that the execution of the computer or other programmable equipment Instructions can provide steps for implementing specified functions.
  • Coupled refers to physical connection, electrical connection, magnetic connection, optical connection, communication connection, functional connection and/or any other connection.

Abstract

Disclosed is an ultrasonic echo signal processing method, comprising the steps of acquiring and analyzing an ultrasonic echo signal of a liver to obtain a quantitative value reflecting the degree of severity of the liver attribute analysis and a credibility of the quantitative value; and displaying the quantitative value and the credibility on a display interface of a display. The quantitative value provides a doctor with the degree of severity of the liver attribute analysis, and the displayed credibility can avoid misleading the doctor, the quantitative value and its credibility can provide the doctor with a comprehensive diagnosis reference, and help the doctor to improve the diagnosis accuracy. Further disclosed is a corresponding ultrasound imaging device.

Description

一种超声成像设备及其超声回波信号的处理方法Ultrasonic imaging equipment and its ultrasonic echo signal processing method 技术领域Technical field
本发明涉及医疗器械领域,具体涉及一种超声成像设备及其超声回波信号的处理方法。The invention relates to the field of medical equipment, in particular to an ultrasonic imaging equipment and a processing method of ultrasonic echo signals.
背景技术Background technique
随着技术的发展,图像处理技术、人工智能技术在医学上的应用越来越常见。目前,在临床产品上的应用大多都是进行医学图像的处理分析,然后直接给出分析结果,这种方式有助于给医生提供参考,但在一定程度上也会影响医生尤其是低年资医生的判断,医生可能会完全参考分析结果进而做出最终判断或结论。然而,分析结果并不是百分之百准确的,如果图像处理技术、人工智能技术基于某种原因没有很好的分析出该医学图像显示的病理,给出的结果准确度并不高,反而会误导医生,会对病人后续的治疗造成很大的影响。尤其针对脂肪肝问题,早期脂肪肝属于可逆转疾病,正确的治疗方式完全可以治愈。然而若因为完全相信人工智能而导致误诊,从而耽误病人病情使脂肪肝严重程度增加甚至转变为不可逆的肝纤维化、肝硬化、肝癌等,对病人造成更大的伤害,这种情况是绝对不能发生的。With the development of technology, the application of image processing technology and artificial intelligence technology in medicine has become more and more common. At present, most of the applications in clinical products are to process and analyze medical images, and then directly give the analysis results. This method is helpful to provide doctors with reference, but to a certain extent, it will also affect doctors, especially low-age doctors. The doctor's judgment, the doctor may make a final judgment or conclusion based on the analysis results. However, the analysis result is not 100% accurate. If the image processing technology and artificial intelligence technology do not analyze the pathology displayed by the medical image for some reason, the accuracy of the result will not be high, but it will mislead the doctor. It will have a great impact on the patient's follow-up treatment. Especially for fatty liver problems, early fatty liver is a reversible disease, and the correct treatment can be completely cured. However, if the misdiagnosis is caused by the complete belief in artificial intelligence, which delays the patient’s condition and causes the severity of fatty liver to increase or even turn into irreversible liver fibrosis, liver cirrhosis, liver cancer, etc., causing greater harm to the patient, this situation is absolutely impossible. occurring.
发明概述Summary of the invention
技术问题technical problem
问题的解决方案The solution to the problem
技术解决方案Technical solutions
本发明主要提供一种超声成像设备及其超声回波信号的处理方法。The present invention mainly provides an ultrasonic imaging equipment and a processing method for ultrasonic echo signals thereof.
一实施例提供一种超声成像设备,包括:An embodiment provides an ultrasound imaging device, including:
超声探头,用于向目标区域发射超声波,并接收所述超声波的回波,获得所述回波的电信号;An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
发射/接收控制电路,用于控制所述超声探头向目标区域发射超声波并接收所述超声波的回波;A transmitting/receiving control circuit for controlling the ultrasonic probe to transmit ultrasonic waves to a target area and receive echoes of the ultrasonic waves;
显示器,用于输出可视化信息;Display, used to output visual information;
处理器,用于:Processor for:
根据所述回波的电信号得到超声回波信号,对所述超声回波信号进行分析,得到肝脏脂肪肝或肝纤维化的严重程度的定量值以及所述定量值的可信度;以及Obtain an ultrasonic echo signal according to the electrical signal of the echo, and analyze the ultrasonic echo signal to obtain a quantitative value of the severity of liver fatty liver or liver fibrosis and the reliability of the quantitative value; and
提供肝脏示意图,将所述定量值标识为肝脏示意图的一个指标,将所述可信度标识为肝脏示意图的另一个指标,在显示器的显示界面上通过标识的肝脏示意图对所述定量值和可信度进行可视化显示。Provide a schematic diagram of the liver, mark the quantitative value as an indicator of the schematic diagram of the liver, and mark the reliability as another indicator of the schematic diagram of the liver. Reliability is displayed visually.
一实施例提供一种超声成像设备,包括:An embodiment provides an ultrasound imaging device, including:
超声探头,用于向目标区域发射超声波,并接收所述超声波的回波,获得所述回波的电信号;An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
发射/接收控制电路,用于控制超声探头向目标区域发射超声波并接收所述超声波的回波;The transmitting/receiving control circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the target area and receive echoes of the ultrasonic waves;
显示器,用于输出可视化信息;Display, used to output visual information;
处理器,用于:Processor for:
根据所述回波的电信号得到超声回波信号,对所述超声回波信号进行分析,得到反映肝脏属性分析的严重程度的定量值以及所述定量值的可信度;以及Obtain an ultrasonic echo signal according to the electrical signal of the echo, analyze the ultrasonic echo signal to obtain a quantitative value reflecting the severity of liver attribute analysis and the credibility of the quantitative value; and
在显示器的显示界面上显示所述定量值和所述可信度。The quantitative value and the credibility are displayed on the display interface of the display.
一实施例提供一种超声回波信号的处理方法,包括:An embodiment provides a method for processing ultrasonic echo signals, including:
获取肝脏的超声回波信号;Obtain the ultrasound echo signal of the liver;
分析所述超声回波信号,识别其中包含的感兴趣图像征,并得到反映所述感兴趣图像征的感兴趣程度的定量值和该定量值的可信度;以及Analyze the ultrasonic echo signal, identify the image sign of interest contained therein, and obtain a quantitative value reflecting the degree of interest of the image sign of interest and the credibility of the quantitative value; and
将所述定量值作为一个维度,所述可信度作为另一个维度,在显示界面上对感兴趣图像征的感兴趣程度进行关联显示。Taking the quantitative value as one dimension and the credibility as another dimension, the degree of interest in the image of interest is displayed in association on the display interface.
依据上述实施例的超声成像设备及其超声回波信号的处理方法,可在显示器的显示界面上直观显示所述定量值和所述可信度。According to the ultrasonic imaging device and the ultrasonic echo signal processing method of the foregoing embodiment, the quantitative value and the credibility can be visually displayed on the display interface of the display.
发明的有益效果The beneficial effects of the invention
对附图的简要说明Brief description of the drawings
附图说明Description of the drawings
图1为本发明一实施例提供的超声成像设备的结构框图;FIG. 1 is a structural block diagram of an ultrasonic imaging device provided by an embodiment of the present invention;
图2为本发明一实施例提供的超声回波信号的处理方法的流程图;2 is a flowchart of a method for processing ultrasonic echo signals according to an embodiment of the present invention;
图3为图2中步骤2的方法流程图;Fig. 3 is a flowchart of the method of step 2 in Fig. 2;
图4为本发明一实施例中,在超声图像上进行定量值及其可信度图形化显示的示意图;4 is a schematic diagram of graphically displaying quantitative values and their credibility on an ultrasound image in an embodiment of the present invention;
图5a为本发明一实施例中,低可信度的第一图形示意图;Fig. 5a is a schematic diagram of a first graph with low reliability in an embodiment of the present invention;
图5b为本发明一实施例中,中可信度的第一图形示意图;FIG. 5b is a schematic diagram of a first graph of medium reliability in an embodiment of the present invention;
图5c为本发明一实施例中,高可信度的第一图形示意图;FIG. 5c is a schematic diagram of a first graphic with high reliability in an embodiment of the present invention; FIG.
图6为本发明一实施例中,坐标与图形结合的第一图形示意图;Fig. 6 is a schematic diagram of a first graph combining coordinates and graphs in an embodiment of the present invention;
图7为本发明一实施例中,以文字显示可信度的第一图形示意图;FIG. 7 is a schematic diagram of a first graph showing credibility in text in an embodiment of the present invention;
图8a为本发明一实施例中,以矩形图表显示定量值及其可信度的示意图;Fig. 8a is a schematic diagram showing quantitative values and their credibility in a rectangular chart in an embodiment of the present invention;
图8b为本发明一实施例中,以三角形图表显示定量值及其可信度的示意图;Fig. 8b is a schematic diagram showing quantitative values and their credibility in a triangular chart in an embodiment of the present invention;
图9为本发明一实施例中,第一图形与图表结合显示定量值及其可信度的示意图;FIG. 9 is a schematic diagram showing the combination of the first graph and the chart to display the quantitative value and its credibility in an embodiment of the present invention;
图10为本发明一实施例中,坐标与图形结合的第一图形示意图;FIG. 10 is a schematic diagram of a first graph combining coordinates and graphs in an embodiment of the present invention;
图11为图2中步骤2一实施例的方法流程图;FIG. 11 is a flowchart of an embodiment of step 2 in FIG. 2;
图12为本发明一实施例中,显示界面的示意图;Figure 12 is a schematic diagram of a display interface in an embodiment of the present invention;
图13为图2中步骤2一实施例的方法流程图。FIG. 13 is a flowchart of an embodiment of step 2 in FIG. 2.
发明实施例Invention embodiment
本发明的实施方式Embodiments of the present invention
下面通过具体实施方式结合附图对本发明作进一步详细说明。其中不同实施方式中类似元件采用了相关联的类似的元件标号。在以下的实施方式中,很多细节描述是为了使得本申请能被更好的理解。然而,本领域技术人员可以毫不费力的认识到,其中部分特征在不同情况下是可以省略的,或者可以由其他元件、材料、方法所替代。在某些情况下,本申请相关的一些操作并没有在说明书中显示或者描述,这是为了避免本申请的核心部分被过多的描述所淹没,而对于本领域技术人员而言,详细描述这些相关操作并不是必要的,他们根据说明书中的描述以及本领域的一般技术知识即可完整了解相关操作。Hereinafter, the present invention will be further described in detail through specific embodiments in conjunction with the accompanying drawings. Among them, similar elements in different embodiments use related similar element numbers. In the following embodiments, many detailed descriptions are used to make this application better understood. However, those skilled in the art can easily realize that some of the features can be omitted under different circumstances, or can be replaced by other elements, materials, and methods. In some cases, some operations related to this application are not shown or described in the specification. This is to avoid the core part of this application being overwhelmed by excessive descriptions. For those skilled in the art, these are described in detail. Related operations are not necessary, they can fully understand the related operations based on the description in the manual and the general technical knowledge in the field.
另外,说明书中所描述的特点、操作或者特征可以以任意适当的方式结合形成各种实施方式。同时,方法描述中的各步骤或者动作也可以按照本领域技术人员所能显而易见的方式进行顺序调换或调整。因此,说明书和附图中的各种顺序只是为了清楚描述某一个实施例,并不意味着是必须的顺序,除非另有说明其中某个顺序是必须遵循的。In addition, the features, operations, or features described in the specification can be combined in any appropriate manner to form various implementations. At the same time, the steps or actions in the method description can also be sequentially exchanged or adjusted in a manner obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for the purpose of clearly describing a certain embodiment, and are not meant to be a necessary sequence, unless it is specified that a certain sequence must be followed.
本文中为部件所编序号本身,例如“第一”、“第二”等,仅用于区分所描述的对象,不具有任何顺序或技术含义。而本申请所说“连接”、“联接”,如无特别说明,均包括直接和间接连接(联接)。The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the described objects and do not have any sequence or technical meaning. The "connection" and "connection" mentioned in this application include direct and indirect connection (connection) unless otherwise specified.
如图1所示,本发明提供的超声成像设备,包括超声探头20、发射/接收电路30(即发射电路310和接收电路320)、处理器40、存储器50和人机交互装置。As shown in Fig. 1, the ultrasonic imaging equipment provided by the present invention includes an ultrasonic probe 20, a transmitting/receiving circuit 30 (ie, a transmitting circuit 310 and a receiving circuit 320), a processor 40, a memory 50 and a human-computer interaction device.
超声探头20包括由阵列式排布的多个阵元组成的换能器(图中未示出),多个阵元排列成一排构成线阵,或排布成二维矩阵构成面阵,多个阵元也可以构成凸阵列。阵元用于根据激励电信号发射超声波束,或将接收的超声波束变换为电信号。因此每个阵元可用于实现电脉冲信号和超声波束的相互转换,从而实现向人体组织的目标区域(例如本实施例中的肝脏)发射超声波、也可用于接收经组织反射回的超声波的回波。在进行超声检测时,可通过发射电路310和接收电路320控制哪些阵元用于发射超声波束,哪些阵元用于接收超声波束,或者控制阵元分时隙用于发射超声波束或接收超声波束的回波。参与超声波发射的阵元可以同时被电信号激励,从而同时发射超声波;或者参与超声波发射的阵元也可以被具有一定时间间隔的若干电信号激励,从而持续发射具有一定时间间隔的超声波。The ultrasonic probe 20 includes a transducer (not shown in the figure) composed of a plurality of array elements arranged in an array, and the plurality of array elements are arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form a surface array. The array elements can also form a convex array. The array element is used to transmit an ultrasonic beam according to the excitation electrical signal, or to transform the received ultrasonic beam into an electrical signal. Therefore, each array element can be used to realize the mutual conversion of electrical pulse signals and ultrasonic beams, so as to realize the transmission of ultrasonic waves to the target area of human tissue (such as the liver in this embodiment), and it can also be used to receive the echo of the ultrasonic waves reflected by the tissue. wave. During ultrasonic testing, the transmitting circuit 310 and the receiving circuit 320 can control which array elements are used to transmit ultrasonic beams and which array elements are used to receive ultrasonic beams, or control the array elements to be used to transmit ultrasonic beams or receive ultrasonic beams in time slots. Echo. The array elements participating in the ultrasonic transmission can be excited by electrical signals at the same time, thereby simultaneously emitting ultrasonic waves; or the array elements participating in the ultrasonic transmission can also be excited by several electrical signals with a certain time interval, so as to continuously emit ultrasonic waves with a certain time interval.
本实施例中,用户通过移动超声探头20选择合适的位置和角度向肝脏10发射超声波并接收由肝脏10返回的超声波的回波,获得并输出该回波的电信号,回波的电信号是按以接收阵元为通道所形成的通道模拟电信号,其携带有幅度信息、频率信息和时间信息。In this embodiment, the user selects a suitable position and angle by moving the ultrasound probe 20 to transmit ultrasound to the liver 10 and receive the echo of the ultrasound returned from the liver 10, and obtain and output the electrical signal of the echo. The electrical signal of the echo is According to the channel analog electrical signal formed by the receiving array element as the channel, it carries amplitude information, frequency information and time information.
发射电路310用于根据发射/接收序列控制模块410的控制产生发射序列,发射序列用于控制多个阵元中的部分或者全部向生物组织发射超声波,发射序列参数包括发射用的阵元位置、阵元数量和超声波束发射参数(例如幅度、频率、 发射次数、发射间隔、发射角度、波型、聚焦位置等)。某些情况下,发射电路310还用于对发射的波束进行相位延迟,使不同的发射阵元按照不同的时间发射超声波,以便各发射超声波束能够在预定的感兴趣区域聚焦。不同的工作模式,例如B图像模式、C图像模式和D图像模式(多普勒模式),发射序列参数可能不同,回波信号经接收电路320接收并经后续的模块和相应算法处理后,可生成反映组织解剖结构的B图像、反映组织解剖结构和血流信息的C图像以及反映多普勒频谱图像的D图像。The transmitting circuit 310 is used to generate a transmitting sequence according to the control of the transmitting/receiving sequence control module 410. The transmitting sequence is used to control some or all of the multiple array elements to transmit ultrasonic waves to biological tissues. The parameters of the transmitting sequence include the position of the transmitting array element, The number of array elements and ultrasonic beam emission parameters (such as amplitude, frequency, number of emission, emission interval, emission angle, wave type, focus position, etc.). In some cases, the transmitting circuit 310 is also used to phase delay the transmitted beams, so that different transmitting array elements emit ultrasonic waves at different times, so that each transmitted ultrasonic beam can be focused on a predetermined region of interest. Different working modes, such as B image mode, C image mode and D image mode (Doppler mode), the transmission sequence parameters may be different. The echo signal is received by the receiving circuit 320 and processed by subsequent modules and corresponding algorithms. Generate a B image that reflects the anatomical structure of the tissue, a C image that reflects the anatomical structure of the tissue and blood flow information, and a D image that reflects the Doppler spectrum image.
接收电路320用于从超声探头20接收超声回波的电信号,并对超声回波的电信号进行处理。接收电路320可以包括一个或多个放大器、模数转换器(ADC)等。接收电路320输出的数据可输出给波束合成模块420进行处理,或输出给存储器50进行存储。The receiving circuit 320 is used to receive the electrical signal of the ultrasonic echo from the ultrasonic probe 20 and process the electrical signal of the ultrasonic echo. The receiving circuit 320 may include one or more amplifiers, analog-to-digital converters (ADC), and the like. The data output by the receiving circuit 320 may be output to the beam synthesis module 420 for processing, or output to the memory 50 for storage.
处理器40用于配置成能够根据特定逻辑指令处理输入数据的中央控制器电路(CPU)、一个或多个微处理器、图形控制器电路(GPU)或其他任何电子部件,其可以根据输入的指令或预定的指令对外围电子部件执行控制,或对存储器50执行数据读取和/或保存,也可以通过执行存储器50中的程序对输入数据进行处理,例如根据一个或多个工作模式对采集的超声数据执行一个或多个处理操作,处理操作包括但不限于调整或限定超声探头20发出的超声波的形式,生成各种图像帧以供后续人机交互装置的显示器60进行显示,或者调整或限定在显示器60上显示的内容和形式,或者调整在显示器60上显示的一个或多个图像显示设置(例如超声图像、界面组件、定位感兴趣区域)。The processor 40 is used to configure a central controller circuit (CPU), one or more microprocessors, a graphics controller circuit (GPU) or any other electronic components that can process input data according to specific logic instructions. Commands or predetermined commands perform control of peripheral electronic components, or perform data reading and/or saving on the memory 50, and input data can also be processed by executing a program in the memory 50, for example, collecting data according to one or more working modes. Perform one or more processing operations on the ultrasound data. The processing operations include, but are not limited to, adjusting or limiting the form of ultrasound emitted by the ultrasound probe 20, generating various image frames for subsequent display on the display 60 of the human-computer interaction device, or adjusting or Define the content and form displayed on the display 60, or adjust one or more image display settings displayed on the display 60 (for example, ultrasound images, interface components, locating regions of interest).
处理器40包括发射/接收序列控制模块410、波束合成模块420、IQ解调模块430和图像处理模块440。The processor 40 includes a transmission/reception sequence control module 410, a beam synthesis module 420, an IQ demodulation module 430, and an image processing module 440.
波束合成模块420和接收电路320信号相连,用于对接收电路320输出的信号进行相应的延时和加权求和等波束合成处理,由于被测组织中的超声波接收点到接收阵元的距离不同,因此,不同接收阵元输出的同一接收点的通道数据具有延时差异,需要进行延时处理,将相位对齐,并将同一接收点的不同通道数据进行加权求和,得到波束合成后的超声图像数据,波束合成模块420输出的超声图像数据也称为射频数据(RF数据)。波束合成模块420将射频数据输出至IQ解 调模块430。在有的实施例中,波束合成模块420也可以将射频数据输出至存储器50进行缓存或保存,或将射频数据直接输出至图像处理模块440进行图像处理。The beam synthesizing module 420 is connected to the receiving circuit 320 to signal the signal output by the receiving circuit 320. It is used to perform beam synthesizing processing such as delay and weighted summation on the signal output by the receiving circuit 320. Because the distance between the ultrasonic receiving point in the measured tissue and the receiving array element is different Therefore, the channel data of the same receiving point output by different receiving array elements has delay differences, and delay processing is required to align the phases, and the different channel data of the same receiving point are weighted and summed to obtain the beam-combined ultrasound Image data, the ultrasound image data output by the beam synthesis module 420 is also called radio frequency data (RF data). The beam synthesis module 420 outputs the radio frequency data to the IQ demodulation module 430. In some embodiments, the beam combining module 420 may also output the radio frequency data to the memory 50 for buffering or storage, or directly output the radio frequency data to the image processing module 440 for image processing.
IQ解调模块430通过IQ解调去除信号载波,提取信号中包含的组织结构信息,并进行滤波去除噪声,此时获取的信号称为基带信号(IQ数据对)。IQ解调模块430将IQ数据对输出至图像处理模块440进行图像处理。The IQ demodulation module 430 removes the signal carrier through IQ demodulation, extracts the organizational structure information contained in the signal, and performs filtering to remove noise. At this time, the acquired signal is called a baseband signal (IQ data pair). The IQ demodulation module 430 outputs the IQ data pair to the image processing module 440 for image processing.
在有的实施例中,IQ解调模块430还将IQ数据对输出至存储器50进行缓存或保存,以便图像处理模块440从存储器50中读出数据进行后续的图像处理。In some embodiments, the IQ demodulation module 430 also buffers or saves the IQ data output to the memory 50, so that the image processing module 440 reads the data from the memory 50 for subsequent image processing.
图像处理模块440用于对波束合成模块420输出的数据或IQ解调模块430输出的数据进行处理,以生成扫描范围内的信号强弱变化的灰度图像,该灰度图像反映组织内部的解剖结构,称为B图像。图像处理模块440可以将B图像输出至人机交互装置的显示器60进行显示。The image processing module 440 is used to process the data output by the beam synthesis module 420 or the data output by the IQ demodulation module 430 to generate a grayscale image of signal strength changes within the scanning range, which reflects the internal anatomy of the tissue The structure is called a B image. The image processing module 440 can output the B image to the display 60 of the human-computer interaction device for display.
人机交互装置用于进行人机交互,即接收用户的输入和输出可视化信息;其接收用户的输入可采用键盘、操作按钮、鼠标、轨迹球等,也可以采用与显示器集成在一起的触控屏;其输出可视化信息采用显示器60。The human-computer interaction device is used for human-computer interaction, that is, receiving user input and outputting visual information; it can receive user input using keyboard, operation buttons, mouse, trackball, etc., or it can use touch integrated with the display Screen; its output visualized information adopts the display 60.
存储器50可为闪存卡、固态存储器、硬盘等。The memory 50 may be a flash memory card, a solid-state memory, a hard disk, and the like.
基于图1所示的超声成像设备,其超声回波信号的处理方法如图2所示,包括以下步骤:Based on the ultrasonic imaging device shown in Fig. 1, the processing method of the ultrasonic echo signal is shown in Fig. 2, including the following steps:
步骤1、处理器40获取肝脏的超声回波信号。处理器40可以从存储器50或外部设备中获取肝脏的超声回波信号,也可以利用超声探头20来获取,本实施例以利用超声探头20来获取为例进行说明。发射/接收序列控制模块410通过发射/接收控制电路30控制超声探头20,使其向肝脏发射超声波,并接收超声波的回波,获得回波的电信号。处理器40根据回波的电信号得到超声回波信号。 Step 1. The processor 40 obtains the ultrasound echo signal of the liver. The processor 40 may obtain the ultrasound echo signal of the liver from the memory 50 or an external device, or may use the ultrasound probe 20 to obtain it. In this embodiment, the ultrasound probe 20 is used as an example for description. The transmitting/receiving sequence control module 410 controls the ultrasonic probe 20 through the transmitting/receiving control circuit 30 to transmit ultrasonic waves to the liver and receive the echoes of the ultrasonic waves to obtain the echoed electrical signals. The processor 40 obtains an ultrasonic echo signal according to the echoed electrical signal.
对根据回波获得的电信号进行的处理可包括模拟信号增益补偿、波束合成、IQ解调、数字信号增益补偿、幅度计算、图像增强等信号处理环节。具体地,通过模拟电路对上述电信号进行前端滤波放大(即增益补偿),再由模数转换器(ADC)转换为数字信号,对模数转换之后的通道数据进一步进行波束合成处理形成扫描线数据,在此之前所进行的数据处理可以统称为前端处理。该阶段 完成后得到的数据,即波束合成模块50输出的超声回波信号可以称为射频信号数据,即RF数据。在获取RF数据之后,通过IQ解调去除信号载波,提取信号中包含的组织结构信息,并进行滤波去除噪声,此时获取的信号为基带信号(IQ数据)。在射频信号处理到基带信号所需的所有处理可以统称为中端处理。最后,对基带信号求取强度并将其灰度级别通过对数压缩和灰度转换,即可得到超声图像,这时所完成的处理可以统称为后端处理。The processing of the electrical signal obtained from the echo may include signal processing links such as analog signal gain compensation, beam synthesis, IQ demodulation, digital signal gain compensation, amplitude calculation, and image enhancement. Specifically, the above-mentioned electrical signal is subjected to front-end filtering and amplification (that is, gain compensation) through an analog circuit, and then converted into a digital signal by an analog-to-digital converter (ADC), and the channel data after the analog-to-digital conversion is further subjected to beam synthesis processing to form a scan line Data, the data processing performed before this can be collectively referred to as front-end processing. The data obtained after the completion of this stage, that is, the ultrasonic echo signal output by the beam synthesis module 50, may be referred to as radio frequency signal data, that is, RF data. After the RF data is acquired, the signal carrier is removed by IQ demodulation, the organizational structure information contained in the signal is extracted, and filtering is performed to remove noise. At this time, the acquired signal is a baseband signal (IQ data). All the processing required from the radio frequency signal processing to the baseband signal can be collectively referred to as mid-end processing. Finally, obtain the intensity of the baseband signal and pass its gray level through logarithmic compression and gray conversion to obtain an ultrasound image. The processing completed at this time can be collectively referred to as back-end processing.
本发明的超声回波信号是对基于超声波的回波得到的电信号进行一级或多级信号处理后的数据,即超声回波信号可以是上述信号处理环节的任一环节产生的数据。例如,超声回波信号可以是波束合成前的模拟或数字超声回波信号,也可以是经波束合成之后的数据,如波束合成模块50输出的超声回波信号,也可以是经IQ解调之后的数据,如IQ解调模块60输出的超声回波信号,也可以是基于波束合成后的数据或IQ解调后的数据进一步处理得到的超声图像数据等。The ultrasonic echo signal of the present invention is the data obtained by performing one-stage or multi-stage signal processing on the electrical signal obtained based on the ultrasonic echo, that is, the ultrasonic echo signal can be the data generated in any of the above-mentioned signal processing links. For example, the ultrasonic echo signal may be an analog or digital ultrasonic echo signal before beam synthesis, or data after beam synthesis, such as the ultrasonic echo signal output by the beam synthesis module 50, or it may be after IQ demodulation. The data, such as the ultrasound echo signal output by the IQ demodulation module 60, may also be ultrasound image data obtained by further processing based on beam-synthesized data or IQ demodulated data.
步骤2、图像处理模块440分析超声回波信号,识别其中包含的感兴趣图像征,并得到反映感兴趣图像征(感兴趣图像特征)的感兴趣程度的定量值和该定量值的可信度。感兴趣图像征用于反映肝脏属性,例如反映肝脏是否有疾病,疾病的类型(脂肪肝、肝纤维化、肿瘤等)等。图像处理模块440根据感兴趣图像特征得到反映感兴趣图像征的感兴趣程度的定量值和该定量值的可信度,感兴趣程度可以是疾病的严重程度,本实施例中,以肝脏脂肪肝或肝纤维化的严重程度为例进行说明。 Step 2. The image processing module 440 analyzes the ultrasonic echo signal, identifies the image sign of interest contained therein, and obtains a quantitative value reflecting the degree of interest of the image sign of interest (image feature of interest) and the credibility of the quantitative value . The image sign of interest is used to reflect the properties of the liver, such as whether the liver has disease, and the type of disease (fatty liver, liver fibrosis, tumor, etc.). The image processing module 440 obtains a quantitative value reflecting the degree of interest of the image sign of interest and the credibility of the quantitative value according to the characteristics of the image of interest. The degree of interest may be the severity of the disease. Or the severity of liver fibrosis as an example.
如上所述,本实施例中,超声回波信号可以为回波的电信号经波束合成之后的信号,其具体可以是波束合成模块420输出的数据,也可以是IQ解调模块430输出的数据,还可以是图像处理模块440处理得到的超声图像数据。处理器40对超声回波信号进行分析,得到脂肪肝或肝纤维化的严重程度的定量值以及所述定量值的可信度,包括:对处理电信号以得到超声图像(灰度图像)的任一信号处理环节的信号进行分析,得到脂肪肝或肝纤维化的严重程度的定量值以及定量值的可信度。As described above, in this embodiment, the ultrasonic echo signal may be the signal after the echoed electrical signal is beam-synthesized, and it may be the data output by the beam-synthesis module 420 or the data output by the IQ demodulation module 430. , It may also be the ultrasound image data processed by the image processing module 440. The processor 40 analyzes the ultrasound echo signal to obtain a quantitative value of the severity of fatty liver or liver fibrosis and the credibility of the quantitative value, including: processing electrical signals to obtain an ultrasound image (gray image) The signal of any signal processing link is analyzed to obtain the quantitative value of the severity of fatty liver or liver fibrosis and the reliability of the quantitative value.
如图3所示,图像处理模块440得到脂肪肝或肝纤维化的严重程度的定量值以及定量值的可信度包括如下步骤:As shown in FIG. 3, the image processing module 440 obtaining the quantitative value of the severity of fatty liver or liver fibrosis and the credibility of the quantitative value includes the following steps:
步骤210、图像处理模块440通过机器学习方法对所述超声回波信号进行自动分析,得到脂肪肝或肝纤维化的严重程度分类结果以及所述分类结果的概率。机器学习可以是传统的机器学习,也可以是深度学习。例如,获取脂肪肝或肝纤维化严重程度不同的肝脏对应的超声回波信号;将超声回波信号作为输入,脂肪肝或肝纤维化的严重程度分类作为标签,进行机器学习或深度学习,训练得到严重程度分类作为特征指标的模型函数;后续,将图像处理模块440获取的超声回波信号输入到模型函数,得到超声回波信号对应肝脏的脂肪肝或肝纤维化的严重程度分类结果以及分类结果的概率。分类结果包括多个分类,如严重、中等、轻微等,每个分类对应一个概率。生成分类结果的同时可生成分类结果的概率,此为机器学习的常规手段,但现有技术通常是将概率最大的结果作为最终的结果,而本申请则不是,本申请通过概率对严重程度进行了二次计算,具体见步骤220。Step 210: The image processing module 440 automatically analyzes the ultrasound echo signal through a machine learning method to obtain a classification result of the severity of fatty liver or liver fibrosis and the probability of the classification result. Machine learning can be traditional machine learning or deep learning. For example, obtain the ultrasound echo signals corresponding to livers with different severity of fatty liver or liver fibrosis; use ultrasound echo signals as input, and classify the severity of fatty liver or liver fibrosis as labels, perform machine learning or deep learning, and train Obtain the severity classification as a model function of the feature index; subsequently, input the ultrasound echo signal obtained by the image processing module 440 into the model function, and obtain the classification result and classification of the severity of the liver fatty liver or liver fibrosis corresponding to the ultrasound echo signal Probability of outcome. The classification results include multiple categories, such as severe, moderate, minor, etc., and each category corresponds to a probability. The probability of the classification result can be generated at the same time as the classification result is generated. This is a conventional method of machine learning. However, the prior art usually uses the most probable result as the final result, which is not the case in this application. This application uses probability to determine the severity For the second calculation, see step 220 for details.
步骤220、图像处理模块440根据分类结果及其概率,对脂肪肝或肝纤维化的严重程度进行定量化计算,得到反映脂肪肝或肝纤维化严重程度的定量值。本实施例中,将概率作为权重,对至少两个分类进行加权计算,得到反映脂肪肝或肝纤维化严重程度的定量值。对至少两个分类进行加权计算,具体可对分类结果中,概率最大的两个或多个分类进行加权计算。例如,分类结果包括严重、中等、轻微和正常,将其根据等级依次表示为3,2,1,0。通过机器学习方法进行自动分析时,输出的分析结果直接为超声回波信号的的严重程度分类结果以及分类结果的概率。例如,机器学习方法得到的分类结果及其概率分别是:严重(3)、60%,中等(2)、20%,轻微(1)、10%,正常(0)、10%;则最终的定量值为:min(2,3)+|2-3|*(60%/(20%+60%))+0.5=3.25。在本示例中,严重对应的定量区间为3-4,中等对应的定量区间为2-3,轻微对应的定量区间为1-2,正常对应的定量区间为0-1。基于上述定量区间的划分,该示例中,最终患者脂肪肝或肝纤维化严重程度位于严重的定量区间内,定量值为3.25。通过这一方法得到的严重程度更为准确,数值化的显示进一步为医生提供了更加准确的参考,便于医生诊断。Step 220: The image processing module 440 quantitatively calculates the severity of fatty liver or liver fibrosis according to the classification result and its probability, and obtains a quantitative value reflecting the severity of fatty liver or liver fibrosis. In this embodiment, the probability is used as the weight, and at least two categories are weighted and calculated to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis. Perform weight calculation on at least two categories. Specifically, weight calculation may be performed on two or more categories with the highest probability among the classification results. For example, the classification results include severe, moderate, mild, and normal, which are represented as 3, 2, 1, 0 according to the grade. When the automatic analysis is performed by the machine learning method, the output analysis result is directly the classification result of the severity of the ultrasonic echo signal and the probability of the classification result. For example, the classification results and their probabilities obtained by the machine learning method are: severe (3), 60%, moderate (2), 20%, mild (1), 10%, normal (0), 10%; the final The quantitative value is: min(2,3)+|2-3|*(60%/(20%+60%))+0.5=3.25. In this example, the quantitative interval corresponding to severe is 3-4, the quantitative interval corresponding to medium is 2-3, the quantitative interval corresponding to slight is 1-2, and the quantitative interval corresponding to normal is 0-1. Based on the division of the above quantitative interval, in this example, the final severity of fatty liver or liver fibrosis of the patient lies within the severe quantitative interval, and the quantitative value is 3.25. The severity obtained by this method is more accurate, and the numerical display further provides doctors with a more accurate reference, which is convenient for doctors to diagnose.
步骤230、图像处理模块440根据分类结果的概率计算定量值的可信度。具体的 ,将可信度分成多个等级,每个等级对应一个概率区间,各个概率区间相加为1,例如,高可信度、中可信度和低可信度分别对应的概率区间为:100%~70%、70%~30%、30%~0%。图像处理模块440根据分类结果(例如n个分类结果)的概率计算定量值的可信度,可根据分类结果的概率的大小,将前两个或n-1个数值大的概率相加,得到可信度的值,较佳的,根据计算定量值所采用的概率来计算该定量值的可信度,如,将计算定量值所采用的各个概率相加。承接上一段中举的分类结果为严重、中等、轻微和正常的例子,将前两个数值大的概率相加计算可信度为:60%+20%=80%,即高可信度,可见,本发明不仅可以得到定性的可信度,甚至还可以得出具体的数值。当然,图像处理模块440还可以根据各个概率的大小,至少对前两个数值大的概率进行统计分析,并判断分析结果与预设的多个可信度区间(概率区间)的关系,将相符的预设可信度区间对应的可信度,作为所述定量值的可信度。Step 230: The image processing module 440 calculates the credibility of the quantitative value according to the probability of the classification result. Specifically, the credibility is divided into multiple levels, each level corresponds to a probability interval, and the probability intervals add up to 1. For example, the probability intervals corresponding to high, medium, and low credibility are: : 100%~70%, 70%~30%, 30%~0%. The image processing module 440 calculates the credibility of the quantitative value according to the probability of the classification result (for example, n classification results). According to the probability of the classification result, the first two or n-1 numerical probabilities are added together to obtain The value of the credibility, preferably, the credibility of the quantitative value is calculated based on the probability used in the calculation of the quantitative value, for example, the probabilities used in the calculation of the quantitative value are added. Continuing the example in the previous paragraph where the classification results are severe, moderate, mild, and normal, the probability of adding the first two values to calculate the reliability is: 60% + 20% = 80%, that is, high confidence. It can be seen that the present invention can not only obtain qualitative credibility, but also obtain specific numerical values. Of course, the image processing module 440 can also perform statistical analysis on the probability of at least the first two numerical values according to the magnitude of each probability, and determine that the relationship between the analysis result and the preset multiple credibility intervals (probability intervals) will be consistent. The credibility corresponding to the preset credibility interval of is used as the credibility of the quantitative value.
本实施例具体以超声回波信号是超声图像为例进行说明,其中,超声图像可以是三维超声图像、超声B图像、超声C图像等,本实施例以超声B图像为例进行说明。图像处理模块440除了通过上述方法得到肝脏脂肪肝或肝纤维化的严重程度的定量值以及所述定量值的可信度外,还可以对所述超声图像进行自动分析,得到反映脂肪肝或肝纤维化严重程度的定量值,例如,获取超声图像的纹理参数和声衰减参数,根据纹理参数和声衰减参数确定所述定量值;并且,根据超声图像的图像质量得到所述定量值的可信度。如果超声图像质量差,自动分析得到的定量值肯定就低,那么其可信度也就低,如此也能准确的得到可信度。This embodiment specifically takes the ultrasound echo signal as an ultrasound image as an example for description, where the ultrasound image may be a three-dimensional ultrasound image, an ultrasound B image, an ultrasound C image, etc., and this embodiment takes an ultrasound B image as an example for description. In addition to obtaining the quantitative value of the severity of liver fatty liver or liver fibrosis and the credibility of the quantitative value through the above-mentioned method, the image processing module 440 can also automatically analyze the ultrasound image to obtain a reflection of fatty liver or liver. The quantitative value of the severity of fibrosis, for example, acquiring the texture parameter and the acoustic attenuation parameter of the ultrasound image, and determining the quantitative value according to the texture parameter and the acoustic attenuation parameter; and obtaining the credibility of the quantitative value according to the image quality of the ultrasound image degree. If the quality of the ultrasound image is poor, the quantitative value obtained by the automatic analysis is definitely low, and its credibility is also low, so that the credibility can be accurately obtained.
得到反映脂肪肝或肝纤维化严重程度的定量值是远远不够的,因为医生通常会认为定量值是百分百准确的,实际上很难做到百分百准确,因此本发明重点通过计算定量值的可信度,使得医生能对定量值进行一个可信度的把握。It is far from enough to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis, because doctors usually think that the quantitative value is 100% accurate, but it is actually difficult to achieve 100% accuracy. Therefore, the present invention focuses on calculation The credibility of the quantitative value enables the doctor to have a certain degree of credibility of the quantitative value.
步骤3、图像处理模块440在显示器50的显示界面上显示计算得到的定量值及其可信度,并且还显示肝脏的超声图像,如图4所示,便于医生在观察患者肝脏的超声图像时,一并了解脂肪肝或肝纤维化的严重程度的定量值及其可信度。其中,图像处理模块440可在显示器50的显示界面上同时显示所述定量值和所述可 信度;也可以在显示器50的显示界面上显示所述定量值,在人机交互装置接收到用户输入的预设指令后同时显示所述定量值和所述可信度。本实施例以同时显示定量值及其可信度为例进行进一步说明。本实施例中,图像处理模块440在显示器50的显示界面上以图形化的方式显示定量值及其可信度,采用图形化的方式显示,更为直观。具体的,图像处理模块440将定量值作为一个维度,可信度作为另一个维度,在显示器50的显示界面上进行二维信息可视化显示。二维信息可视化显示有多种多样,以下通过举例来进一步说明。 Step 3. The image processing module 440 displays the calculated quantitative value and its credibility on the display interface of the display 50, and also displays the ultrasound image of the liver, as shown in FIG. 4, which is convenient for the doctor to observe the ultrasound image of the patient’s liver. , And understand the quantitative value and credibility of the severity of fatty liver or liver fibrosis. Wherein, the image processing module 440 may simultaneously display the quantitative value and the credibility on the display interface of the display 50; it may also display the quantitative value on the display interface of the display 50, and the human-computer interaction device receives the user After the preset instruction is input, the quantitative value and the credibility are displayed at the same time. In this embodiment, the simultaneous display of the quantitative value and its credibility is taken as an example for further description. In this embodiment, the image processing module 440 graphically displays the quantitative value and its credibility on the display interface of the display 50, and the graphical display is more intuitive. Specifically, the image processing module 440 takes the quantitative value as one dimension and the credibility as another dimension, and visually displays two-dimensional information on the display interface of the display 50. There are many kinds of two-dimensional information visualization display, which will be further explained by examples below.
一实施例中,如图5所示,图像处理模块440提供第一图形A,第一图形A可以从存储器或外部设备中获取,也可以由图像处理模块440生成;在显示器50的显示界面上显示第一图形A,以第一图形A的量化指标标识定量值,以第一图形的定性指标标识可信度。第一图像A可以是各种规则或不规则的几何图形等,本实施例中,第一图像A为肝脏的示意图,便于直观展示肝脏的脂肪肝程度及其可信度。其中,量化指标包括定量值及其量程,还包括图形大小、填充面积、填充图块数量中的至少一种,如图5中,第一图形A的量化指标包括第一图像A的填充面积(图中灰色区域)、定量值(2.4)及其量程(0-4)。填充面积越大,脂肪肝越严重。从医生的角度来看,基本扫一眼就能知道脂肪肝或肝纤维化的严重程度偏中等,进一步看数值即可得知定量值为2.4(中等),非常方便直观。除了图5的填充面积,量化指标还可以采用线段来表示定量值,如图6和图7所示。In an embodiment, as shown in FIG. 5, the image processing module 440 provides a first graphic A. The first graphic A may be obtained from a memory or an external device, or may be generated by the image processing module 440; on the display interface of the display 50 The first graph A is displayed, the quantitative value is identified by the quantitative index of the first graph A, and the credibility is identified by the qualitative index of the first graph. The first image A can be various regular or irregular geometric figures, etc. In this embodiment, the first image A is a schematic diagram of the liver, which is convenient for visually showing the degree of fatty liver of the liver and its credibility. Wherein, the quantitative index includes the quantitative value and its range, and also includes at least one of the figure size, the filling area, and the number of filled tiles. As shown in FIG. 5, the quantitative index of the first figure A includes the filling area of the first image A ( The gray area in the figure), the quantitative value (2.4) and its range (0-4). The larger the filling area, the more serious the fatty liver. From a doctor's point of view, one can know that the severity of fatty liver or liver fibrosis is moderate at a glance, and the quantitative value is 2.4 (medium) by looking at the value, which is very convenient and intuitive. In addition to the filling area in Figure 5, the quantitative indicators can also use line segments to represent quantitative values, as shown in Figures 6 and 7.
定性指标包括线条颜色、填充颜色、填充图案、填充图块大小、填充图块数量、文字、字母、数字中的至少一种;图5中为填充颜色(灰色),灰色越深说明可信度越高,图5a-c分别表示低可信度、中可信度和高可信度三种情况,同样一目了然。图6中,定性指标为填充图块大小,辅以坐标,可得知图6中定性值的可信度为中等。Qualitative indicators include at least one of line color, filling color, filling pattern, filling block size, number of filling blocks, text, letters, and numbers; the filling color (gray) in Figure 5, the darker the gray indicates the credibility The higher the higher, Figures 5a-c show the low-reliability, medium-reliability, and high-reliability situations, which are also clear at a glance. In Fig. 6, the qualitative index is the size of the filling block, supplemented by the coordinates, it can be seen that the credibility of the qualitative value in Fig. 6 is medium.
一实施例中,如图7所示,图像处理模块440在显示器50的显示界面上显示第一图形A,以第一图形A的量化指标标识定量值,并在第一图形A上标识可信度的值。图7中,直接以文字的形式显示可信度,当然还可以进一步显示可信度的具体数值。In one embodiment, as shown in FIG. 7, the image processing module 440 displays the first graphic A on the display interface of the display 50, uses the quantitative index of the first graphic A to mark the quantitative value, and marks the credibility on the first graphic A. The value of degrees. In Figure 7, the credibility is directly displayed in the form of text, of course, the specific value of the credibility can be further displayed.
除了上述以肝脏示意图来展示外,还可以采用图表的形式进行展示。一实施例 中,如图8a所示,图像处理模块440在显示器50的显示界面上显示用于展示所述定量值和可信度的图表,所述图表的第一坐标轴为定量值,第二坐标轴为可信度。图表可以是各种几何图形,坐标轴也不局限于常规的垂直坐标轴。如图8a所示,横轴代表脂肪肝严重程度的定量值,越往右脂肪肝越严重;纵轴代表该脂肪肝定量值的可信度,越往上定量值的可信度越高,图中定量值为2.8,可信度为中。图8b所示,金字塔横向轴代表脂肪肝严重程度定量值,纵向轴代表脂肪肝定量值的可信度,金字塔从左到右依次代表脂肪肝严重程度从正常到轻度到中度再到重度(严重);金字塔从塔底到塔顶依次代表脂肪肝定量值的可信度从低到高,图中定量值为2.6,可信度为高。同样的,为了便于突出显示,还可以在图表中依据坐标系建立几何图形,如图8a的矩形、图8b的三角形,以该几何图形的量化指标标识定量值,以该几何图形的定性指标标识可信度,量化指标和定性指标在上述实施例中已阐述,在此不赘述。In addition to the liver diagram shown above, it can also be displayed in the form of a graph. In one embodiment, as shown in FIG. 8a, the image processing module 440 displays a chart for displaying the quantitative value and reliability on the display interface of the display 50, and the first coordinate axis of the chart is the quantitative value, and the first axis of the chart is the quantitative value. The two axis is the credibility. The chart can be a variety of geometric figures, and the coordinate axis is not limited to the conventional vertical coordinate axis. As shown in Figure 8a, the horizontal axis represents the quantitative value of the severity of fatty liver, the farther to the right the more serious the fatty liver; the vertical axis represents the reliability of the quantitative value of fatty liver, the higher the higher the reliability of the quantitative value, The quantitative value in the figure is 2.8, and the reliability is medium. As shown in Figure 8b, the horizontal axis of the pyramid represents the quantitative value of fatty liver severity, and the longitudinal axis represents the reliability of the quantitative value of fatty liver. The pyramid from left to right represents the severity of fatty liver from normal to mild to moderate to severe. (Serious); The pyramid from the bottom of the tower to the top of the tower represents the reliability of the quantitative value of fatty liver from low to high. The quantitative value in the figure is 2.6, and the reliability is high. Similarly, in order to facilitate highlighting, you can also create geometric figures in the chart according to the coordinate system, such as the rectangle in Figure 8a and the triangle in Figure 8b. The quantitative value of the geometric figure is used to identify the quantitative value, and the qualitative indicator of the geometric figure is used to identify the quantitative value. The credibility, the quantitative index and the qualitative index have been described in the above embodiments, and will not be repeated here.
当然,还可以结合第一图形以及图表的形式进行显示,如图9所示,一实施例中,图像处理模块440在显示器50的显示界面上显示第一图形A和第一坐标轴D,所述第一图形A的定性指标标识所述可信度,所述第一图形A对应于第一坐标轴D的位置标识所述定量值。第一图形A和第一坐标轴D可以通过直线连接,便于在坐标轴上定位具体的定量值;也可以采用一个从第一图形A发出的箭头指示到第一坐标轴D上,以便于在坐标轴上定位具体的定量值。第一图形A具有上述的定性指标,以标识可信度。图6实际上也是这种表现形式,只是其第一坐标轴依附在肝脏示意图上,当然,如图6所示,还可以设置第二坐标轴,第二坐标轴跟随定量值而移动,通过图形B与第二坐标轴的交点标识可信度。如图10所示,第一坐标轴和第二坐标轴还可以分别设置在第一图像A的相邻两侧。Of course, it can also be displayed in the form of a first graph and a chart. As shown in FIG. 9, in an embodiment, the image processing module 440 displays the first graph A and the first coordinate axis D on the display interface of the display 50, so The qualitative index of the first graph A identifies the credibility, and the position of the first graph A corresponding to the first coordinate axis D identifies the quantitative value. The first graph A and the first coordinate axis D can be connected by a straight line to facilitate the positioning of specific quantitative values on the coordinate axis; an arrow from the first graph A can also be used to indicate to the first coordinate axis D to facilitate the Position the specific quantitative value on the coordinate axis. The first graph A has the above-mentioned qualitative index to identify the credibility. Figure 6 is actually in this form, but the first coordinate axis is attached to the schematic diagram of the liver. Of course, as shown in Figure 6, a second coordinate axis can also be set, and the second coordinate axis moves with the quantitative value. The intersection of B and the second coordinate axis identifies the credibility. As shown in FIG. 10, the first coordinate axis and the second coordinate axis may also be set on adjacent two sides of the first image A, respectively.
上述实施例描述了定量值及其可信度同时显示的方案,基于上述实施例,在显示定量值时,先隐藏(不显示)可信度,在人机交互装置接收到用户输入的预设指令后同时显示定量值及其可信度,也就是将隐藏的可信度显示出来,最终的效果依然如图5-图10所示,不做赘述。The above embodiment describes the solution of displaying the quantitative value and its credibility at the same time. Based on the above embodiment, when the quantitative value is displayed, the credibility is first hidden (not displayed), and the user-input preset is received in the human-computer interaction device. After the instruction, the quantitative value and its credibility are displayed at the same time, that is, the hidden credibility is displayed. The final effect is still shown in Figure 5 to Figure 10, so I will not repeat it.
综上所述,本发明针对脂肪肝或肝纤维化严重程度,在计算得到的脂肪肝或肝纤维化严重程度定量值的基础上,还计算得到定量值的可信度,并对定量值和 可信度这两种参数进行联合二维可视化显示,给医生提供了准确、全面的参考信息,提高了医生诊断的准确性。In summary, the present invention aims at the severity of fatty liver or liver fibrosis. On the basis of the calculated quantitative value of fatty liver or liver fibrosis, the reliability of the quantitative value is calculated, and the quantitative value is summed up. The reliability of these two parameters is combined with two-dimensional visual display, which provides doctors with accurate and comprehensive reference information and improves the accuracy of doctors' diagnosis.
另外,前述内容中提到一种计算定量值及其可信度的方法:获取超声图像的纹理参数和声衰减参数,根据纹理参数和声衰减参数确定定量值;并且,根据超声图像的图像质量得到所述定量值的可信度(如图11所示)。下面的内容将具体阐述这一过程。In addition, the foregoing content mentions a method for calculating the quantitative value and its reliability: acquiring the texture parameter and sound attenuation parameter of the ultrasound image, and determining the quantitative value according to the texture parameter and the sound attenuation parameter; and, according to the image quality of the ultrasound image The credibility of the quantitative value is obtained (as shown in Figure 11). The following content will explain this process in detail.
处理器40对获取的超声回波数据进行处理,得到肝脏10的纹理参数和声衰减参数,并根据该纹理参数和声衰减参数确定该肝脏10的脂肪肝或肝纤维化的严重程度的定量值。以超声回波数据为超声图像为例,处理器40对肝脏10的超声图像进行处理,确定该超声图像中肝脏10的一些相关参数,例如,该肝脏10的纹理参数和声衰减参数等,然后根据该肝脏10的纹理参数和声衰减参数确定该肝脏10的脂肪肝或肝纤维化的严重程度的定量值,从而对脂肪肝或肝纤维化的严重程度进行直观地量化分析。处理器40获得的超声图像和该肝脏10的相关参数可以存储于存储器50中。The processor 40 processes the acquired ultrasonic echo data to obtain the texture parameter and the sound attenuation parameter of the liver 10, and determines the quantitative value of the severity of fatty liver or liver fibrosis of the liver 10 according to the texture parameter and the sound attenuation parameter . Taking the ultrasound echo data as an ultrasound image as an example, the processor 40 processes the ultrasound image of the liver 10 to determine some related parameters of the liver 10 in the ultrasound image, for example, the texture parameters and sound attenuation parameters of the liver 10, etc. The quantitative value of the severity of fatty liver or liver fibrosis of the liver 10 is determined according to the texture parameter and the acoustic attenuation parameter of the liver 10, so as to intuitively quantitatively analyze the severity of fatty liver or liver fibrosis. The ultrasound image obtained by the processor 40 and related parameters of the liver 10 may be stored in the memory 50.
下面对本发明图11所示实施例中,计算定量值及其可信度的方法进行详细描述。The method for calculating the quantitative value and its reliability in the embodiment shown in FIG. 11 of the present invention will be described in detail below.
步骤210’、处理器40获取超声图像的纹理参数和声衰减参数。In step 210', the processor 40 obtains the texture parameters and sound attenuation parameters of the ultrasound image.
处理器40得到肝脏10的超声图像后,进一步获取该超声图像中的纹理参数和声衰减参数。其中,一种可选的实现方式:根据该超声图像和第一预置模型确定该超声图像的纹理参数,其中,该第一预置模型为根据历史数据训练得到的模型。After the processor 40 obtains the ultrasound image of the liver 10, it further obtains texture parameters and sound attenuation parameters in the ultrasound image. Among them, an optional implementation manner: determine the texture parameters of the ultrasound image according to the ultrasound image and a first preset model, where the first preset model is a model obtained by training based on historical data.
首先,先介绍第一预置模型的建立过程,其过程包括:First of all, first introduce the process of establishing the first preset model. The process includes:
步骤2101、获取历史数据。Step 2101: Obtain historical data.
其中,历史数据包括多个肝脏的脂肪肝或肝纤维化的严重程度的分析数据。可选的,该分析数据包括多个肝脏的医生诊断数据和/或多个肝脏的病理诊断数据。例如,医生诊断数据可以包括对该多个肝脏的诊断结果,如脂肪肝或肝纤维化的严重程度分类:正常、轻微脂肪肝、中度脂肪肝、重度脂肪肝等。而病理诊断数据可以是通过对由外部手术获取到的肝脏进行病理分析得到的数据。Among them, the historical data includes analysis data of the severity of fatty liver or liver fibrosis of multiple livers. Optionally, the analysis data includes doctor diagnosis data of multiple livers and/or pathological diagnosis data of multiple livers. For example, the doctor's diagnosis data may include the diagnosis results of the multiple livers, such as the severity classification of fatty liver or liver fibrosis: normal, mild fatty liver, moderate fatty liver, severe fatty liver, etc. The pathological diagnosis data may be data obtained through pathological analysis of the liver obtained by external surgery.
步骤2102、根据历史数据建立该第一预置模型。Step 2102: Establish the first preset model based on historical data.
根据该历史数据和预置的算法训练得到该第一预置模型,其中,预置的算法可以包括深度学习或者机器学习等算法。The first preset model is obtained by training based on the historical data and preset algorithms, where the preset algorithm may include algorithms such as deep learning or machine learning.
本申请一个可能的实施方式中,处理器40可以直接对整张超声图像进行处理,即将该超声图像作为输入参数输入该第一预置模型,得到特征图像;然后对该特征图像进行纹理特性分析,得到该肝脏10的纹理参数。或者是,处理器40将该超声图像作为输入参数输入该第一预置模型,得到该肝脏10的纹理参数。In a possible implementation manner of the present application, the processor 40 may directly process the entire ultrasound image, that is, input the ultrasound image as an input parameter into the first preset model to obtain a feature image; and then perform texture characteristic analysis on the feature image , The texture parameters of the liver 10 are obtained. Alternatively, the processor 40 inputs the ultrasound image as an input parameter into the first preset model to obtain the texture parameter of the liver 10.
另一种可能的实施方式中,处理器40确定该超声图像中的待分析区域,即感兴趣区域,其中,该感兴趣区域可以包括全部的肝脏区域或者部分肝脏区域;然后将该待分析区域的图像作为输入参数输入该第一预置模型,得到特征图像;然后对该特征图像进行纹理特性分析,得到该肝脏10的纹理参数。或者是,该处理器40将该待分析区域的图像作为输入参数输入该第一预置模型,得到该肝脏10的纹理参数。In another possible implementation manner, the processor 40 determines the region to be analyzed in the ultrasound image, that is, the region of interest, where the region of interest may include the entire liver region or part of the liver region; and then the region to be analyzed The image of is input into the first preset model as an input parameter to obtain a characteristic image; then, texture characteristic analysis is performed on the characteristic image to obtain the texture parameter of the liver 10. Alternatively, the processor 40 inputs the image of the region to be analyzed as an input parameter into the first preset model to obtain the texture parameter of the liver 10.
可选的,本申请实施例中获取超声图像的声衰减参数有多种方式,下面举例说明:Optionally, there are multiple ways to acquire the sound attenuation parameter of the ultrasound image in the embodiment of the present application, and the following examples illustrate:
1、通过超声波的回波在待分析区域的预置深度范围的信号幅度值确定该超声图像的声衰减参数。1. Determine the sound attenuation parameter of the ultrasound image by the signal amplitude value of the ultrasonic echo in the preset depth range of the area to be analyzed.
首先,确定超声图像中的待分析区域,即感兴趣区域,根据该待分析区域对应的超声波的回波在预置深度的信号幅度值确定该待分析区域的声衰减参数,其中,深度即待分析区域中的组织与探头的距离。例如,声衰减参数可以是超声波的回波在待分析区域的第一深度处的信号幅度值与超声波的回波在待分析区域的第二深度处的信号幅度值的比值,其中,第一深度可以是近场深度,第二深度可以远场深度,或者第一深度是远场深度,第二深度是近场深度,此处不做具体限定。First, determine the region to be analyzed in the ultrasound image, that is, the region of interest, and determine the sound attenuation parameter of the region to be analyzed according to the signal amplitude value of the ultrasonic echo corresponding to the region to be analyzed at a preset depth. The distance between the tissue in the analysis area and the probe. For example, the acoustic attenuation parameter may be the ratio of the signal amplitude value of the ultrasonic echo at the first depth of the area to be analyzed to the signal amplitude value of the ultrasonic echo at the second depth of the area to be analyzed, where the first depth It can be the near field depth, the second depth can be the far field depth, or the first depth is the far field depth and the second depth is the near field depth, which is not specifically limited here.
2、根据待分析区域的图像在预置深度范围所对应的灰度值确定该超声图像的声衰减参数。2. Determine the sound attenuation parameter of the ultrasound image according to the gray value corresponding to the image of the area to be analyzed in the preset depth range.
首先,确定超声图像中的待分析区域,即感兴趣区域,其中,该感兴趣区域可以由系统自动确定,也可以由用户手动输入确定,根据待分析区域的图像在预 置深度范围内所对应的灰度值来确定该待分析区域的声衰减参数,其中,深度即待分析区域中的组织与探头的距离。例如,声衰减参数可以为该待分析区域的图像在第一深度处所对应的灰度值与该待分析区域的图像在第二深度处所对应的灰度值的比值。First, determine the region to be analyzed in the ultrasound image, that is, the region of interest, where the region of interest can be determined automatically by the system or manually input by the user, according to the corresponding image of the region to be analyzed within the preset depth range To determine the sound attenuation parameter of the area to be analyzed, the depth is the distance between the tissue in the area to be analyzed and the probe. For example, the sound attenuation parameter may be the ratio of the gray value corresponding to the image of the area to be analyzed at the first depth to the gray value of the image of the area to be analyzed at the second depth.
步骤220’、处理器40根据纹理参数和声衰减参数确定肝脏10的脂肪肝定量参数。In step 220', the processor 40 determines the fatty liver quantitative parameter of the liver 10 according to the texture parameter and the sound attenuation parameter.
可选的,处理器40根据该纹理参数和声衰减参数确定该肝脏10的脂肪肝定量参数。Optionally, the processor 40 determines the fatty liver quantitative parameter of the liver 10 according to the texture parameter and the sound attenuation parameter.
具体的,处理器根据该纹理参数、声衰减参数和第二预置模型确定肝脏10的所述定量值。其中,该第二预置模型可以是根据深度学习或者机器学习等算法训练得到的模型,将该纹理参数和该声衰减参数作为输入该第二预置模型,得到该肝脏10的所述定量值。可选的,该第二预置模型也可以函数关系,例如,该函数关系为一个权重关系式,该权重关系式包括权重系数,而权重系数可以是系统默认的或者用户自定义的,具体此处不做限定。例如,纹理参数为A,声衰减参数为B,权重系数为4∶6,则所述定量值为A*0.4+B*0.6。可选的,处理器40也可以将纹理参数和声衰减参数作平均计算,得到肝脏10的所述定量值,例如,纹理参数为A,声衰减参数为B,即权重系数为1∶1,则所述定量值为A*0.5+B*0.5。Specifically, the processor determines the quantitative value of the liver 10 according to the texture parameter, the sound attenuation parameter, and the second preset model. The second preset model may be a model trained according to algorithms such as deep learning or machine learning, and the texture parameter and the sound attenuation parameter are used as input to the second preset model to obtain the quantitative value of the liver 10 . Optionally, the second preset model may also be a functional relationship. For example, the functional relationship is a weight relationship, and the weight relationship includes a weight coefficient, and the weight coefficient may be system default or user-defined. There is no limit. For example, if the texture parameter is A, the sound attenuation parameter is B, and the weight coefficient is 4:6, the quantitative value is A*0.4+B*0.6. Optionally, the processor 40 may also average the texture parameter and the sound attenuation parameter to obtain the quantitative value of the liver 10, for example, the texture parameter is A, the sound attenuation parameter is B, that is, the weight coefficient is 1:1, Then the quantitative value is A*0.5+B*0.5.
本申请的一个实施例中,在上述显示定量值及其可信度的同时,还显示该超声图像以及对应的声衰减参数和纹理参数。In an embodiment of the present application, while the quantitative value and its credibility are displayed above, the ultrasound image and the corresponding sound attenuation parameter and texture parameter are also displayed.
示例性的,如图12,在显示器中显示超声图像701,待分析区域702和703;通过阴影或者颜色或者框型等方式区别显示该待分析区域702。703为前述图形化显示的定量值及其可信度,如图5-图10所示。Exemplarily, as shown in Fig. 12, the ultrasound image 701, the regions to be analyzed 702 and 703 are displayed on the display; the region to be analyzed 702 is distinguished and displayed by means of shadow, color, or frame. 703 is the quantitative value and Its credibility is shown in Figure 5 to Figure 10.
步骤230’、处理器40根据超声图像的图像质量得到定量值的可信度。图像质量可以根据超声图像的整体亮度、伪影等进行评估。例如,将超声图像与预设的标准图像信息库进行匹配,得到与标准图像信息库中的标准图像的匹配度;该匹配度就反映了图像质量,匹配度越高说明图像质量越高,可信度也就越高。In step 230', the processor 40 obtains the credibility of the quantitative value according to the image quality of the ultrasound image. The image quality can be evaluated based on the overall brightness and artifacts of the ultrasound image. For example, the ultrasound image is matched with the preset standard image information library to obtain the matching degree with the standard image in the standard image information library; the matching degree reflects the image quality, and the higher the matching degree, the higher the image quality. The higher the credibility.
当然,在有的实施例中,也可以采用超声回波数据中除超声图像以外的数据进 行定量值计算,例如,根据接收电路320输出的数据计算定量值、根据波束合成模块420输出的数据计算定量值、或根据IQ解调模块430输出的数据计算定量值等,换而言之,上述根据超声图像计算定量值的实施例可扩展到根据超声回波数据计算定量值,其步骤如图13所示。由于根据超声回波数据计算定量值及其可信度的具体过程与上述根据超声图像来计算的过程相同,在此不做赘述。Of course, in some embodiments, data other than the ultrasound image in the ultrasound echo data can also be used to calculate the quantitative value, for example, the quantitative value is calculated based on the data output by the receiving circuit 320, and the calculation is based on the data output by the beam synthesis module 420. Quantitative value, or calculation of quantitative value based on the data output by IQ demodulation module 430, in other words, the above embodiment of calculating quantitative value based on ultrasound image can be extended to calculate quantitative value based on ultrasound echo data, the steps are shown in Figure 13 Shown. Since the specific process of calculating the quantitative value and its credibility based on the ultrasound echo data is the same as the above-mentioned calculation process based on the ultrasound image, it will not be repeated here.
本领域技术人员可以理解,上述实施方式中各种方法的全部或部分功能可以通过硬件的方式实现,也可以通过计算机程序的方式实现。当上述实施方式中全部或部分功能通过计算机程序的方式实现时,该程序可以存储于一计算机可读存储介质中,存储介质可以包括:只读存储器、随机存储器、磁盘、光盘、硬盘等,通过计算机执行该程序以实现上述功能。例如,将程序存储在设备的存储器中,当通过处理器执行存储器中程序,即可实现上述全部或部分功能。另外,当上述实施方式中全部或部分功能通过计算机程序的方式实现时,该程序也可以存储在服务器、另一计算机、磁盘、光盘、闪存盘或移动硬盘等存储介质中,通过下载或复制保存到本地设备的存储器中,或对本地设备的系统进行版本更新,当通过处理器执行存储器中的程序时,即可实现上述实施方式中全部或部分功能。Those skilled in the art can understand that all or part of the functions of the various methods in the above-mentioned embodiments can be realized by hardware or by computer programs. When all or part of the functions in the above embodiments are realized by a computer program, the program may be stored in a computer-readable storage medium. The storage medium may include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc. The computer executes the program to realize the above-mentioned functions. For example, the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized. In addition, when all or part of the functions in the above embodiments are implemented by a computer program, the program can also be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a mobile hard disk, and saved by downloading or copying. In the memory of the local device, or update the version of the system of the local device, when the program in the memory is executed by the processor, all or part of the functions in the foregoing embodiments can be realized.
本文参照了各种示范实施例进行说明。然而,本领域的技术人员将认识到,在不脱离本文范围的情况下,可以对示范性实施例做出改变和修正。例如,各种操作步骤以及用于执行操作步骤的组件,可以根据特定的应用或考虑与系统的操作相关联的任何数量的成本函数以不同的方式实现(例如一个或多个步骤可以被删除、修改或结合到其他步骤中)。This document is described with reference to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications can be made to the exemplary embodiments without departing from the scope of this document. For example, various operation steps and components used to perform the operation steps can be implemented in different ways according to a specific application or considering any number of cost functions associated with the operation of the system (for example, one or more steps can be deleted, Modify or incorporate into other steps).
另外,如本领域技术人员所理解的,本文的原理可以反映在计算机可读存储介质上的计算机程序产品中,该可读存储介质预装有计算机可读程序代码。任何有形的、非暂时性的计算机可读存储介质皆可被使用,包括磁存储设备(硬盘、软盘等)、光学存储设备(CD-ROM、DVD、Blu Ray盘等)、闪存和/或诸如此类。这些计算机程序指令可被加载到通用计算机、专用计算机或其他可编程数据处理设备上以形成机器,使得这些在计算机上或其他可编程数据处理装置上执行的指令可以生成实现指定的功能的装置。这些计算机程序指令也可以存 储在计算机可读存储器中,该计算机可读存储器可以指示计算机或其他可编程数据处理设备以特定的方式运行,这样存储在计算机可读存储器中的指令就可以形成一件制造品,包括实现指定功能的实现装置。计算机程序指令也可以加载到计算机或其他可编程数据处理设备上,从而在计算机或其他可编程设备上执行一系列操作步骤以产生一个计算机实现的进程,使得在计算机或其他可编程设备上执行的指令可以提供用于实现指定功能的步骤。In addition, as understood by those skilled in the art, the principles herein can be reflected in a computer program product on a computer-readable storage medium, which is pre-installed with computer-readable program code. Any tangible, non-transitory computer-readable storage medium can be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROM, DVD, Blu Ray disks, etc.), flash memory and/or the like . These computer program instructions can be loaded on a general-purpose computer, a special-purpose computer, or other programmable data processing equipment to form a machine, so that these instructions executed on the computer or other programmable data processing device can generate a device that realizes the specified function. These computer program instructions can also be stored in a computer-readable memory, which can instruct a computer or other programmable data processing equipment to operate in a specific manner, so that the instructions stored in the computer-readable memory can form a piece of Manufactured products, including realizing devices that realize designated functions. Computer program instructions can also be loaded on a computer or other programmable data processing equipment, thereby executing a series of operation steps on the computer or other programmable equipment to produce a computer-implemented process, so that the execution of the computer or other programmable equipment Instructions can provide steps for implementing specified functions.
虽然在各种实施例中已经示出了本文的原理,但是许多特别适用于特定环境和操作要求的结构、布置、比例、元件、材料和部件的修改可以在不脱离本披露的原则和范围内使用。以上修改和其他改变或修正将被包含在本文的范围之内。Although the principles herein have been shown in various embodiments, many modifications to the structure, arrangement, proportions, elements, materials, and components that are particularly suitable for specific environments and operating requirements can be made without departing from the principles and scope of this disclosure. use. The above modifications and other changes or amendments will be included in the scope of this article.
前述具体说明已参照各种实施例进行了描述。然而,本领域技术人员将认识到,可以在不脱离本披露的范围的情况下进行各种修正和改变。因此,对于本披露的考虑将是说明性的而非限制性的意义上的,并且所有这些修改都将被包含在其范围内。同样,有关于各种实施例的优点、其他优点和问题的解决方案已如上所述。然而,益处、优点、问题的解决方案以及任何能产生这些的要素,或使其变得更明确的解决方案都不应被解释为关键的、必需的或必要的。本文中所用的术语“包括”和其任何其他变体,皆属于非排他性包含,这样包括要素列表的过程、方法、文章或设备不仅包括这些要素,还包括未明确列出的或不属于该过程、方法、系统、文章或设备的其他要素。此外,本文中所使用的术语“耦合”和其任何其他变体都是指物理连接、电连接、磁连接、光连接、通信连接、功能连接和/或任何其他连接。The foregoing detailed description has been described with reference to various embodiments. However, those skilled in the art will recognize that various modifications and changes can be made without departing from the scope of this disclosure. Therefore, the consideration of this disclosure will be in an illustrative rather than restrictive sense, and all these modifications will be included in its scope. Likewise, the advantages, other advantages, and solutions to problems of the various embodiments have been described above. However, benefits, advantages, solutions to problems, and any solutions that can produce these or make them more specific should not be construed as critical, necessary, or necessary. The term "including" and any other variants thereof used in this article are non-exclusive inclusions. Such a process, method, article or device that includes a list of elements not only includes these elements, but also includes those that are not explicitly listed or are not part of the process. , Methods, systems, articles or other elements of equipment. In addition, the term "coupled" and any other variations thereof used herein refer to physical connection, electrical connection, magnetic connection, optical connection, communication connection, functional connection and/or any other connection.
具有本领域技术的人将认识到,在不脱离本发明的基本原理的情况下,可以对上述实施例的细节进行许多改变。因此,本发明的范围应根据以下权利要求确定。Those skilled in the art will recognize that many changes can be made to the details of the above-described embodiments without departing from the basic principles of the present invention. Therefore, the scope of the present invention should be determined according to the following claims.

Claims (31)

  1. 一种超声成像设备,其特征在于,包括:An ultrasonic imaging equipment, characterized in that it comprises:
    超声探头,用于向目标区域发射超声波,并接收所述超声波的回波,获得所述回波的电信号;An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
    发射/接收控制电路,用于控制所述超声探头向目标区域发射超声波并接收所述超声波的回波;A transmitting/receiving control circuit for controlling the ultrasonic probe to transmit ultrasonic waves to a target area and receive echoes of the ultrasonic waves;
    显示器,用于输出可视化信息;Display, used to output visual information;
    处理器,用于:Processor for:
    根据所述电信号得到超声回波信号,对所述超声回波信号进行分析,得到肝脏脂肪肝或肝纤维化的严重程度的定量值以及所述定量值的可信度;以及Obtain an ultrasonic echo signal according to the electrical signal, analyze the ultrasonic echo signal to obtain a quantitative value of the severity of liver fatty liver or liver fibrosis and the reliability of the quantitative value; and
    提供肝脏示意图,将所述定量值标识为肝脏示意图的一个指标,将所述可信度标识为肝脏示意图的另一个指标,在显示器的显示界面上通过标识的肝脏示意图对所述定量值和可信度进行可视化显示。Provide a schematic diagram of the liver, mark the quantitative value as an indicator of the schematic diagram of the liver, and mark the reliability as another indicator of the schematic diagram of the liver. Reliability is displayed visually.
  2. 如权利要求1所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上通过标识的肝脏示意图对所述定量值和可信度进行可视化显示包括:The ultrasonic imaging device according to claim 1, wherein the processor visually displaying the quantitative value and the credibility through the marked schematic diagram of the liver on the display interface of the display comprises:
    在显示器的显示界面上显示所述肝脏示意图,以肝脏示意图的量化指标标识所述定量值,以肝脏示意图的定性指标标识所述可信度。The schematic diagram of the liver is displayed on the display interface of the display, the quantitative value is identified by the quantitative index of the schematic liver diagram, and the credibility is identified by the qualitative index of the schematic liver diagram.
  3. 如权利要求1所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上通过标识的肝脏示意图对所述定量值和可信度进行可视化显示包括:The ultrasonic imaging device according to claim 1, wherein the processor visually displaying the quantitative value and the credibility through the marked schematic diagram of the liver on the display interface of the display comprises:
    在显示器的显示界面上显示所述肝脏示意图,以肝脏示意图的量化指标标识所述定量值,并在肝脏示意图上标识所述可信度的值。The schematic diagram of the liver is displayed on the display interface of the display, the quantitative value is identified by the quantitative index of the schematic diagram of the liver, and the credibility value is identified on the schematic diagram of the liver.
  4. 如权利要求2或3所述的超声成像设备,其特征在于,所述量化指 标包括所述定量值,还包括大小、填充面积、填充图块数量中的至少一种。The ultrasonic imaging device according to claim 2 or 3, wherein the quantitative index includes the quantitative value, and further includes at least one of a size, a filling area, and the number of filled tiles.
  5. 如权利要求2所述的超声成像设备,其特征在于,所述定性指标包括线条颜色、填充颜色、填充图案、填充图块大小、填充图块数量、文字、字母、数字中的至少一种。The ultrasonic imaging device according to claim 2, wherein the qualitative index includes at least one of line color, filling color, filling pattern, filling block size, filling block number, text, letters, and numbers.
  6. 如权利要求1所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上通过标识的肝脏示意图对所述定量值和可信度进行可视化显示包括:The ultrasonic imaging device according to claim 1, wherein the processor visually displaying the quantitative value and the credibility through the marked schematic diagram of the liver on the display interface of the display comprises:
    在显示器的显示界面上显示所述肝脏示意图,以所述肝脏示意图的填充面积标识所述定量值,以所述肝脏示意图的填充颜色标识所述可信度。The schematic diagram of the liver is displayed on the display interface of the display, the quantitative value is identified by the fill area of the schematic liver, and the credibility is identified by the fill color of the schematic liver.
  7. 一种超声成像设备,其特征在于,包括:An ultrasonic imaging equipment, characterized in that it comprises:
    超声探头,用于向目标区域发射超声波,并接收所述超声波的回波,获得所述回波的电信号;An ultrasonic probe for transmitting ultrasonic waves to a target area and receiving echoes of the ultrasonic waves to obtain electrical signals of the echoes;
    发射/接收控制电路,用于控制超声探头向目标区域发射超声波并接收所述超声波的回波;The transmitting/receiving control circuit is used to control the ultrasonic probe to transmit ultrasonic waves to the target area and receive echoes of the ultrasonic waves;
    显示器,用于输出可视化信息;Display, used to output visual information;
    处理器,用于:Processor for:
    根据所述电信号得到超声回波信号,对所述超声回波信号进行分析,得到反映肝脏属性分析的严重程度的定量值以及所述定量值的可信度;以及Obtain an ultrasonic echo signal according to the electrical signal, analyze the ultrasonic echo signal to obtain a quantitative value reflecting the severity of liver attribute analysis and the credibility of the quantitative value; and
    在显示器的显示界面上显示所述定量值和所述可信度。The quantitative value and the credibility are displayed on the display interface of the display.
  8. 如权利要求7所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上显示所述定量值和所述可信度包括:8. The ultrasonic imaging device of claim 7, wherein the processor displaying the quantitative value and the credibility on a display interface of a display comprises:
    在显示器的显示界面上同时显示所述定量值和所述可信度;或者,Simultaneously display the quantitative value and the credibility on the display interface of the display; or,
    在显示器的显示界面上显示所述定量值,在接收到用户输入的预设指令后同时显示所述定量值和所述可信度。The quantitative value is displayed on the display interface of the display, and the quantitative value and the credibility are displayed simultaneously after receiving the preset instruction input by the user.
  9. 如权利要求7所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上显示所述定量值和所述可信度包括:8. The ultrasonic imaging device of claim 7, wherein the processor displaying the quantitative value and the credibility on a display interface of a display comprises:
    在显示器的显示界面上以图形化的方式显示所述定量值和所述可信度。The quantitative value and the credibility are displayed graphically on the display interface of the display.
  10. 如权利要求7所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上显示所述定量值和所述可信度包括:8. The ultrasonic imaging device of claim 7, wherein the processor displaying the quantitative value and the credibility on a display interface of a display comprises:
    将所述定量值作为一个维度,所述可信度作为另一个维度,在显示器的显示界面上进行可视化显示。Taking the quantitative value as one dimension and the credibility as another dimension, it is visually displayed on the display interface of the display.
  11. 如权利要求10所述的超声成像设备,其特征在于,所述处理器将所述定量值作为一个维度,所述可信度作为另一个维度,在显示器的显示界面上进行可视化显示包括:The ultrasound imaging device of claim 10, wherein the processor uses the quantitative value as one dimension and the reliability as another dimension, and performing visual display on the display interface of the display comprises:
    在显示器的显示界面上显示第一图形,以第一图形的量化指标标识所述定量值,以第一图形的定性指标标识所述可信度;Displaying a first graphic on the display interface of the display, using a quantitative indicator of the first graphic to identify the quantitative value, and using a qualitative indicator of the first graphic to identify the credibility;
    或,在显示器的显示界面上显示第一图形,以第一图形的量化指标标识所述定量值,并在第一图形上标识所述可信度的值。Or, displaying a first graphic on the display interface of the display, marking the quantitative value with a quantitative index of the first graphic, and marking the credibility value on the first graphic.
  12. 如权利要求11所述的超声成像设备,其特征在于,所述量化指标包括所述定量值,还包括大小、填充面积、填充图块数量中的至少一种,所述定性指标包括线条颜色、填充颜色、填充图案、填充图块大小、填充图块数量、文字、字母、数字中的至少一种。The ultrasound imaging device according to claim 11, wherein the quantitative index includes the quantitative value, and further includes at least one of a size, a filling area, and the number of filled tiles, and the qualitative index includes line color, At least one of filling color, filling pattern, filling block size, number of filling blocks, text, letters, and numbers.
  13. 如权利要求11所述的超声成像设备,其特征在于,所述第一图形为肝脏示意图。The ultrasound imaging device of claim 11, wherein the first figure is a schematic diagram of a liver.
  14. 如权利要求10所述的超声成像设备,其特征在于,所述处理器将所述定量值作为一个维度,所述可信度作为另一个维度,在显示器的显示界面上进行可视化显示包括:The ultrasound imaging device of claim 10, wherein the processor uses the quantitative value as one dimension and the reliability as another dimension, and performing visual display on the display interface of the display comprises:
    在显示器的显示界面上显示用于展示所述定量值和可信度的图表,所述图表的第一坐标轴为定量值,第二坐标轴为可信度。A chart for displaying the quantitative value and reliability is displayed on the display interface of the display, the first coordinate axis of the chart is the quantitative value, and the second coordinate axis is the reliability.
  15. 如权利要求10所述的超声成像设备,其特征在于,所述处理器将所述定量值作为一个维度,所述可信度作为另一个维度,在显示 器的显示界面上进行可视化显示包括:The ultrasound imaging device according to claim 10, wherein the processor uses the quantitative value as one dimension and the reliability as another dimension, and performing visual display on the display interface of the display comprises:
    在显示器的显示界面上显示第一图形和第一坐标轴,所述第一图形的定性指标标识所述可信度,所述第一图形对应于第一坐标轴的位置标识所述定量值。A first graph and a first coordinate axis are displayed on the display interface of the display, the qualitative index of the first graph identifies the credibility, and the position of the first graph corresponding to the first coordinate axis identifies the quantitative value.
  16. 如权利要求7所述的超声成像设备,其特征在于,所述肝脏属性分析包括脂肪肝或肝纤维化。8. The ultrasound imaging device of claim 7, wherein the liver attribute analysis includes fatty liver or liver fibrosis.
  17. 如权利要求1或16所述的超声成像设备,其特征在于,所述处理器对所述超声回波信号进行分析,得到肝脏脂肪肝或肝纤维化严重程度的定量值以及所述定量值的可信度包括:The ultrasound imaging device according to claim 1 or 16, wherein the processor analyzes the ultrasound echo signal to obtain a quantitative value of the severity of liver fatty liver or liver fibrosis and a quantitative value of the quantitative value. Credibility includes:
    通过机器学习方法对所述超声回波信号进行自动分析,得到脂肪肝或肝纤维化的严重程度分类结果以及所述分类结果的概率;Automatically analyze the ultrasound echo signal by a machine learning method to obtain a classification result of the severity of fatty liver or liver fibrosis and the probability of the classification result;
    根据所述分类结果及其概率,对脂肪肝或肝纤维化的严重程度进行定量化计算,得到反映脂肪肝或肝纤维化严重程度的定量值;According to the classification result and its probability, quantitatively calculate the severity of fatty liver or liver fibrosis to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis;
    根据所述分类结果的概率计算所述定量值的可信度。The reliability of the quantitative value is calculated according to the probability of the classification result.
  18. 如权利要求1或16所述的超声成像设备,其特征在于,所述超声回波信号为超声图像;所述处理器对所述超声回波信号进行处理,得到脂肪肝或肝纤维化严重程度的定量值以及所述定量值的可信度包括:The ultrasound imaging device according to claim 1 or 16, wherein the ultrasound echo signal is an ultrasound image; the processor processes the ultrasound echo signal to obtain the severity of fatty liver or liver fibrosis The quantitative value of and the credibility of the quantitative value include:
    对所述超声图像进行自动分析,得到反映脂肪肝或肝纤维化严重程度的定量值,根据所述超声图像的图像质量得到所述定量值的可信度。The ultrasound image is automatically analyzed to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis, and the credibility of the quantitative value is obtained according to the image quality of the ultrasound image.
  19. 如权利要求1或7所述的超声成像设备,其特征在于,所述处理器在显示器的显示界面上显示所述定量值和所述可信度的同时,还显示所述肝脏的超声图像。8. The ultrasound imaging device according to claim 1 or 7, wherein the processor displays the quantitative value and the credibility on the display interface of the display, and at the same time also displays the ultrasound image of the liver.
  20. 如权利要求17所述的超声成像设备,其特征在于,所述分类结果包括多个分类,每个分类对应一个概率;所述处理器根据所述分类结果及其概率,对脂肪肝或肝纤维化的严重程度进行定量化计算,得到反映脂肪肝或肝纤维化严重程度的定量值包括:The ultrasound imaging device according to claim 17, wherein the classification result includes a plurality of classifications, each of which corresponds to a probability; and the processor determines the fatty liver or liver fiber according to the classification result and its probability. The severity of liver fibrosis is quantitatively calculated, and the quantitative values that reflect the severity of fatty liver or liver fibrosis include:
    将概率作为权重,对至少两个分类进行加权计算,得到反映脂肪肝或肝纤维化严重程度的定量值。The probability is used as a weight, and at least two classifications are weighted and calculated to obtain a quantitative value reflecting the severity of fatty liver or liver fibrosis.
  21. 如权利要求17所述的超声成像设备,其特征在于,处理器根据所述分类结果的概率计算所述定量值的可信度包括:The ultrasound imaging device of claim 17, wherein the processor calculating the credibility of the quantitative value according to the probability of the classification result comprises:
    根据各个概率的大小,至少将前两个数值大的概率相加,得到所述可信度的值;According to the magnitude of each probability, at least the first two numerical probabilities are added together to obtain the reliability value;
    或者,根据各个概率的大小,至少对前两个数值大的概率进行统计分析,并判断分析结果与预设的多个可信度区间的关系,将相符的预设可信度区间对应的可信度,作为所述定量值的可信度。Or, according to the magnitude of each probability, at least the first two numerical probabilities are statistically analyzed, and the relationship between the analysis result and the preset multiple credibility intervals is judged, and the corresponding preset credibility interval is corresponding to the reliability interval. Reliability, as the credibility of the quantitative value.
  22. 如权利要求17所述的超声成像设备,其特征在于,所述处理器还用于对所述电信号进行信号处理得到所述超声回波信号,所述信号处理包括以下的一项或多项:增益补偿、模数转换、波束合成、正交解调、基带信号强度求取和灰度级对数压缩。The ultrasonic imaging device according to claim 17, wherein the processor is further configured to perform signal processing on the electrical signal to obtain the ultrasonic echo signal, and the signal processing includes one or more of the following : Gain compensation, analog-to-digital conversion, beam synthesis, quadrature demodulation, baseband signal strength calculation and gray-scale logarithmic compression.
  23. 一种超声回波信号的处理方法,其特征在于包括:A processing method for ultrasonic echo signals, which is characterized in that it includes:
    获取肝脏的超声回波信号;Obtain the ultrasound echo signal of the liver;
    分析所述超声回波信号,识别其中包含的感兴趣图像征,并得到反映所述感兴趣图像征的感兴趣程度的定量值和该定量值的可信度;以及Analyze the ultrasonic echo signal, identify the image sign of interest contained therein, and obtain a quantitative value reflecting the degree of interest of the image sign of interest and the credibility of the quantitative value; and
    将所述定量值作为一个维度,所述可信度作为另一个维度,在显示界面上对感兴趣图像征的感兴趣程度进行关联显示。Taking the quantitative value as one dimension and the credibility as another dimension, the degree of interest in the image of interest is displayed in association on the display interface.
  24. 如权利要求23所述的方法,其特征在于,将所述定量值作为一个维度,所述可信度作为另一个维度,在显示器上进行关联显示包括:22. The method of claim 23, wherein using the quantitative value as one dimension and the credibility as another dimension, and performing an associated display on a display comprises:
    在显示器的显示界面上显示第一图形,以第一图形的量化指标标识所述定量值,以第一图形的定性指标标识所述可信度;Displaying a first graphic on the display interface of the display, using a quantitative indicator of the first graphic to identify the quantitative value, and using a qualitative indicator of the first graphic to identify the credibility;
    或在显示器的显示界面上显示第一图形,以第一图形的量化指标标识所述定量值,并在第一图形上显示所述可信度的值。Or the first graph is displayed on the display interface of the display, the quantitative value is identified by the quantitative index of the first graph, and the credibility value is displayed on the first graph.
  25. 如权利要求24所述的方法,其特征在于,所述量化指标包括所述 定量值,还包括大小、填充面积、填充图块数量中的至少一种;The method according to claim 24, wherein the quantitative index comprises the quantitative value, and further comprises at least one of size, filling area, and number of filling tiles;
    和/或,所述定性指标包括线条颜色、填充颜色、填充图案、填充图块大小、填充图块数量、文字、字母、数字中的至少一种。And/or, the qualitative index includes at least one of line color, filling color, filling pattern, filling block size, number of filling blocks, text, letters, and numbers.
  26. 如权利要求24所述的方法,其特征在于,所述第一图形为肝脏示意图。The method of claim 24, wherein the first graphic is a schematic diagram of a liver.
  27. 如权利要求23所述的方法,其特征在于,将所述定量值作为一个维度,所述可信度作为另一个维度,在显示界面上进行关联显示包括:22. The method of claim 23, wherein using the quantitative value as one dimension and the credibility as another dimension, and performing an associated display on a display interface comprises:
    在显示界面上显示用于展示所述定量值和可信度的图表,所述图表的第一坐标轴为定量值,第二坐标轴为可信度。A graph for displaying the quantitative value and the credibility is displayed on the display interface, the first coordinate axis of the graph is the quantitative value, and the second coordinate axis is the credibility.
  28. 如权利要求23所述的方法,其特征在于,将所述定量值作为一个维度,所述可信度作为另一个维度,在显示界面上进行关联显示包括:22. The method of claim 23, wherein using the quantitative value as one dimension and the credibility as another dimension, and performing an associated display on a display interface comprises:
    在显示器的显示界面上显示第一图形和第一坐标轴,所述第一图形的定性指标标识所述可信度,所述第一图形对应于第一坐标轴的位置标识所述定量值。A first graph and a first coordinate axis are displayed on the display interface of the display, the qualitative index of the first graph identifies the credibility, and the position of the first graph corresponding to the first coordinate axis identifies the quantitative value.
  29. 如权利要求23所述的方法,其特征在于,识别其中包含的感兴趣图像征,并得到反映所述感兴趣图像征的感兴趣程度的定量值和该定量值的可信度包括:The method of claim 23, wherein identifying the image feature of interest contained therein, and obtaining a quantitative value reflecting the degree of interest of the image feature of interest and the credibility of the quantitative value comprises:
    通过机器学习方法对识别的感兴趣图像征进行分类,得到感兴趣图像征的感兴趣程度分类结果以及所述分类结果的概率;Classify the recognized image signs of interest by a machine learning method, and obtain a classification result of the degree of interest of the image signs of interest and the probability of the classification result;
    根据所述分类结果及其概率,对感兴趣图像征的感兴趣程度进行定量化计算,得到反映感兴趣图像征的感兴趣程度的定量值;根据所述分类结果的概率计算所述定量值的可信度。According to the classification result and its probability, quantitatively calculate the degree of interest of the image sign of interest to obtain a quantitative value reflecting the degree of interest of the image sign of interest; calculate the quantitative value according to the probability of the classification result Credibility.
  30. 如权利要求23所述的方法,其特征在于,所述超声回波信号为超声图像;识别其中包含的感兴趣图像征,并得到反映所述感兴趣图像征的感兴趣程度的定量值和该定量值的可信度包括:The method according to claim 23, wherein the ultrasound echo signal is an ultrasound image; the image sign of interest contained therein is identified, and the quantitative value reflecting the degree of interest of the image sign of interest and the The credibility of quantitative values includes:
    对所述超声图像进行处理,得到反映感兴趣图像征的感兴趣程度 的定量值,根据所述超声图像的图像质量得到所述定量值的可信度。The ultrasound image is processed to obtain a quantitative value reflecting the degree of interest of the image feature of interest, and the credibility of the quantitative value is obtained according to the image quality of the ultrasound image.
  31. 如权利要求29所述的方法,其特征在于,根据所述分类结果的概率计算所述定量值的可信度包括:The method of claim 29, wherein calculating the credibility of the quantitative value according to the probability of the classification result comprises:
    根据各个概率的大小,至少将前两个数值大的概率相加,得到所述可信度的值;According to the magnitude of each probability, at least the first two numerical probabilities are added together to obtain the reliability value;
    或者,根据各个概率的大小,至少对前两个数值大的概率进行统计分析,并判断分析结果与预设的多个可信度区间的关系,将相符的预设可信度区间对应的可信度,作为所述定量值的可信度。Or, according to the magnitude of each probability, at least the first two numerical probabilities are statistically analyzed, and the relationship between the analysis result and the preset multiple credibility intervals is judged, and the corresponding preset credibility interval is corresponding to the reliability interval. Reliability, as the credibility of the quantitative value.
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