WO2021014171A3 - Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring. - Google Patents

Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring. Download PDF

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Publication number
WO2021014171A3
WO2021014171A3 PCT/GB2020/051784 GB2020051784W WO2021014171A3 WO 2021014171 A3 WO2021014171 A3 WO 2021014171A3 GB 2020051784 W GB2020051784 W GB 2020051784W WO 2021014171 A3 WO2021014171 A3 WO 2021014171A3
Authority
WO
WIPO (PCT)
Prior art keywords
beat
fixed location
invasive
real
blood pressure
Prior art date
Application number
PCT/GB2020/051784
Other languages
French (fr)
Other versions
WO2021014171A2 (en
Inventor
Darren Spencer
Peter BALMFORTH
Original Assignee
DP Holding (U.K) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1910660.8A external-priority patent/GB201910660D0/en
Priority claimed from GBGB1911249.9A external-priority patent/GB201911249D0/en
Priority claimed from GBGB1911247.3A external-priority patent/GB201911247D0/en
Priority claimed from GBGB1911251.5A external-priority patent/GB201911251D0/en
Application filed by DP Holding (U.K) Limited filed Critical DP Holding (U.K) Limited
Priority to US17/629,742 priority Critical patent/US20220249055A1/en
Priority to EP20771334.8A priority patent/EP4003180A2/en
Priority to CN202080067767.XA priority patent/CN114521126A/en
Priority to JP2022504715A priority patent/JP2022547784A/en
Publication of WO2021014171A2 publication Critical patent/WO2021014171A2/en
Publication of WO2021014171A3 publication Critical patent/WO2021014171A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/04—Measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/02—Measuring pulse or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • A61B8/085—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A61B8/4236—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4272—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4272—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
    • A61B8/4281—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue characterised by sound-transmitting media or devices for coupling the transducer to the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4411—Device being modular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4438—Means for identifying the diagnostic device, e.g. barcodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4455—Features of the external shape of the probe, e.g. ergonomic aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4477—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device using several separate ultrasound transducers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • A61B8/4488—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer the transducer being a phased array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/486—Diagnostic techniques involving arbitrary m-mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5292—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves using additional data, e.g. patient information, image labeling, acquisition parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/56—Details of data transmission or power supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/56—Details of data transmission or power supply
    • A61B8/565—Details of data transmission or power supply involving data transmission via a network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/58—Testing, adjusting or calibrating the diagnostic device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

According to an aspect of the invention, there is provided an ambulatory system for determining a cardiac parameter at a fixed location within the cardiovascular system of a subject. The system comprises a wearable sensor including an ultrasound transducer. The wearable sensor can contact the skin of the subject and be positioned proximate to the fixed location. The system comprises a data collection module that is in communication with the ultrasound transducer. The ultrasound transducer is configured to detect a pressure wave passing through the fixed location. The data collection module is configured to collect data relating to the pressure wave passing through the fixed location, analyse the pressure wave, and determine at least one cardiac parameter based on the analysis.
PCT/GB2020/051784 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring. WO2021014171A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US17/629,742 US20220249055A1 (en) 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring
EP20771334.8A EP4003180A2 (en) 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring
CN202080067767.XA CN114521126A (en) 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring
JP2022504715A JP2022547784A (en) 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat ambulatory blood pressure monitoring

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GBGB1910660.8A GB201910660D0 (en) 2019-07-25 2019-07-25 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring
GB1910660.8 2019-07-25
GBGB1911249.9A GB201911249D0 (en) 2019-08-06 2019-08-06 System and method for facilitating diagnosis of cardiac rhythm changes with the aid of a pulse pressure wave (PPW) and a digital computer from ambulatory
GB1911251.5 2019-08-06
GBGB1911247.3A GB201911247D0 (en) 2019-08-06 2019-08-06 Actigraphy embedded within an ambulatory blood pressure system (ABPS)
GBGB1911251.5A GB201911251D0 (en) 2019-08-06 2019-08-06 Ambulatory blood pressure system (ABPS) each patch comprising two pieces for monitoring peripheral or central blood pressure when working independently or in
GB1911247.3 2019-08-06
GB1911249.9 2019-08-06

Publications (2)

Publication Number Publication Date
WO2021014171A2 WO2021014171A2 (en) 2021-01-28
WO2021014171A3 true WO2021014171A3 (en) 2021-03-04

Family

ID=72470548

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2020/051784 WO2021014171A2 (en) 2019-07-25 2020-07-24 Non-invasive, real-time, beat-to-beat, ambulatory blood pressure monitoring.

Country Status (5)

Country Link
US (1) US20220249055A1 (en)
EP (1) EP4003180A2 (en)
JP (1) JP2022547784A (en)
CN (1) CN114521126A (en)
WO (1) WO2021014171A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4059440A1 (en) * 2021-03-15 2022-09-21 Pulsify Medical Ultrasound system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130116615A1 (en) * 2011-11-08 2013-05-09 Elwha Llc Inflatable cuff with built-in drug delivery device for dynamic drug therapy response to blood pressure incidents
WO2015193917A2 (en) * 2014-06-20 2015-12-23 Healthcare Technology Innovation Centre Method and system for cuff-less blood pressure (bp) measurement of a subject
US20160345930A1 (en) * 2015-05-25 2016-12-01 Seiko Epson Corporation Blood pressure measurement device and blood pressure measurement method
US20180078155A1 (en) * 2016-09-16 2018-03-22 Qualcomm Incorporated Multi-model blood pressure estimation
WO2019073236A1 (en) * 2017-10-11 2019-04-18 Darren Spencer Non-invasive ambulatory monitoring of pulse transit time

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7733224B2 (en) * 2006-06-30 2010-06-08 Bao Tran Mesh network personal emergency response appliance
US11253159B2 (en) * 2010-01-31 2022-02-22 Vladimir Shusterman Tracking cardiac forces and arterial blood pressure using accelerometers
US20170080255A1 (en) * 2014-03-15 2017-03-23 Cerevast Medical Inc. Thin and wearable ultrasound phased array devices
WO2018189622A1 (en) 2017-04-13 2018-10-18 Atcor Medical Pty Ltd Non-invasive blood pressure measurement
US11357981B2 (en) * 2018-03-01 2022-06-14 Adventus Ventures, Llc Systems and methods for controlling blood pressure
US20220117503A1 (en) * 2020-10-20 2022-04-21 The Regents Of The University Of California Integrated chemical/ultrasonic transducer sensor
US20220000378A1 (en) * 2021-07-06 2022-01-06 Stichting Imec Nederland Method and a system for estimating a measure of cardiovascular health of a subject

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130116615A1 (en) * 2011-11-08 2013-05-09 Elwha Llc Inflatable cuff with built-in drug delivery device for dynamic drug therapy response to blood pressure incidents
WO2015193917A2 (en) * 2014-06-20 2015-12-23 Healthcare Technology Innovation Centre Method and system for cuff-less blood pressure (bp) measurement of a subject
US20160345930A1 (en) * 2015-05-25 2016-12-01 Seiko Epson Corporation Blood pressure measurement device and blood pressure measurement method
US20180078155A1 (en) * 2016-09-16 2018-03-22 Qualcomm Incorporated Multi-model blood pressure estimation
WO2019073236A1 (en) * 2017-10-11 2019-04-18 Darren Spencer Non-invasive ambulatory monitoring of pulse transit time

Also Published As

Publication number Publication date
CN114521126A (en) 2022-05-20
EP4003180A2 (en) 2022-06-01
JP2022547784A (en) 2022-11-16
WO2021014171A2 (en) 2021-01-28
US20220249055A1 (en) 2022-08-11

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