WO2020081795A8 - Data based cancer research and treatment systems and methods - Google Patents

Data based cancer research and treatment systems and methods Download PDF

Info

Publication number
WO2020081795A8
WO2020081795A8 PCT/US2019/056713 US2019056713W WO2020081795A8 WO 2020081795 A8 WO2020081795 A8 WO 2020081795A8 US 2019056713 W US2019056713 W US 2019056713W WO 2020081795 A8 WO2020081795 A8 WO 2020081795A8
Authority
WO
WIPO (PCT)
Prior art keywords
data
database
storing
sequencing
application specific
Prior art date
Application number
PCT/US2019/056713
Other languages
French (fr)
Other versions
WO2020081795A1 (en
Inventor
Shane Colley
Isaiah SIMPSON
Brian Reuter
Bob TELL
Hailey LEFKOFSKY
Hunter Lane
Kevin White
Nike BEAUBIER
Stephen Bush
Aly KHAN
Denise LAU
Kaanan Shah
Eric Lefkofsky
Original Assignee
Tempus Labs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA3116712A priority Critical patent/CA3116712A1/en
Priority to EP19873536.7A priority patent/EP3857555A4/en
Priority to AU2019359878A priority patent/AU2019359878A1/en
Priority to US16/771,451 priority patent/US11640859B2/en
Application filed by Tempus Labs filed Critical Tempus Labs
Priority to US16/789,288 priority patent/US20200258601A1/en
Publication of WO2020081795A1 publication Critical patent/WO2020081795A1/en
Publication of WO2020081795A8 publication Critical patent/WO2020081795A8/en
Priority to AU2020313915A priority patent/AU2020313915A1/en
Priority to EP20840833.6A priority patent/EP3997243A4/en
Priority to US16/927,976 priority patent/US20200365232A1/en
Priority to CA3147100A priority patent/CA3147100A1/en
Priority to PCT/US2020/041862 priority patent/WO2021011507A1/en
Priority to AU2020326626A priority patent/AU2020326626A1/en
Priority to PCT/US2020/044795 priority patent/WO2021026097A1/en
Priority to EP20851017.2A priority patent/EP4007522A4/en
Priority to US16/984,072 priority patent/US10978196B2/en
Priority to JP2022506631A priority patent/JP2022543240A/en
Priority to PCT/US2020/046513 priority patent/WO2021034712A1/en
Priority to US16/994,315 priority patent/US11367508B2/en
Priority to US17/207,972 priority patent/US11682481B2/en
Priority to US17/750,055 priority patent/US20220351805A1/en
Priority to US18/298,371 priority patent/US20230245788A1/en
Priority to US18/319,212 priority patent/US20230386643A1/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H15/00—ICT specially adapted for medical reports, e.g. generation or transmission thereof
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Databases & Information Systems (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)

Abstract

A method and system for conducting genomic sequencing, the method comprising storing a set of user application programs wherein each of the programs requires an application specific subset of data, for each of a plurality of patients that have cancerous cells and that receive cancer treatment, obtaining clinical records data in original forms including cancer state information, treatment types and treatment efficacy information, storing the clinical records data in a semi-structured first database, for each patient, using a genomic sequencer to generate genomic sequencing data for the patient's cancerous cells and normal cells, storing the sequencing data in the first database, shaping at least a subset of the first database data to generate system structured data including clinical record data and sequencing data wherein the system structured data is optimized for searching, storing the system structured data in a second database, for each user application program, selecting the application specific subset of data from the second database and storing the application specific subset of data in a structure optimized for application program interfacing in a third database.
PCT/US2019/056713 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods WO2020081795A1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
CA3116712A CA3116712A1 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
EP19873536.7A EP3857555A4 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
AU2019359878A AU2019359878A1 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
US16/771,451 US11640859B2 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
US16/789,288 US20200258601A1 (en) 2018-10-17 2020-02-12 Targeted-panel tumor mutational burden calculation systems and methods
AU2020313915A AU2020313915A1 (en) 2019-07-12 2020-07-13 Adaptive order fulfillment and tracking methods and systems
PCT/US2020/041862 WO2021011507A1 (en) 2019-07-12 2020-07-13 Adaptive order fulfillment and tracking methods and systems
CA3147100A CA3147100A1 (en) 2019-07-12 2020-07-13 Adaptive order fulfillment and tracking methods and systems
EP20840833.6A EP3997243A4 (en) 2019-07-12 2020-07-13 Adaptive order fulfillment and tracking methods and systems
US16/927,976 US20200365232A1 (en) 2018-10-17 2020-07-13 Adaptive order fulfillment and tracking methods and systems
JP2022506631A JP2022543240A (en) 2019-08-02 2020-08-03 Data-based mental illness research and treatment systems and methods
AU2020326626A AU2020326626A1 (en) 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods
US16/984,072 US10978196B2 (en) 2018-10-17 2020-08-03 Data-based mental disorder research and treatment systems and methods
PCT/US2020/044795 WO2021026097A1 (en) 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods
EP20851017.2A EP4007522A4 (en) 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods
PCT/US2020/046513 WO2021034712A1 (en) 2019-08-16 2020-08-14 Systems and methods for detecting cellular pathway dysregulation in cancer specimens
US16/994,315 US11367508B2 (en) 2019-08-16 2020-08-14 Systems and methods for detecting cellular pathway dysregulation in cancer specimens
US17/207,972 US11682481B2 (en) 2018-10-17 2021-03-22 Data-based mental disorder research and treatment systems and methods
US17/750,055 US20220351805A1 (en) 2019-08-16 2022-05-20 Systems and methods for detecting cellular pathway dysregulation in cancer specimens
US18/298,371 US20230245788A1 (en) 2018-10-17 2023-04-11 Data based cancer research and treatment systems and methods
US18/319,212 US20230386643A1 (en) 2018-10-17 2023-05-17 Data-based mental disorder research and treatment systems and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862746997P 2018-10-17 2018-10-17
US62/746,997 2018-10-17

Related Child Applications (6)

Application Number Title Priority Date Filing Date
US16/771,451 A-371-Of-International US11640859B2 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
US16/789,288 Continuation-In-Part US20200258601A1 (en) 2018-10-17 2020-02-12 Targeted-panel tumor mutational burden calculation systems and methods
US16/927,976 Continuation-In-Part US20200365232A1 (en) 2018-10-17 2020-07-13 Adaptive order fulfillment and tracking methods and systems
US16/984,072 Continuation-In-Part US10978196B2 (en) 2018-10-17 2020-08-03 Data-based mental disorder research and treatment systems and methods
US16/994,315 Continuation-In-Part US11367508B2 (en) 2019-08-16 2020-08-14 Systems and methods for detecting cellular pathway dysregulation in cancer specimens
US18/298,371 Continuation US20230245788A1 (en) 2018-10-17 2023-04-11 Data based cancer research and treatment systems and methods

Publications (2)

Publication Number Publication Date
WO2020081795A1 WO2020081795A1 (en) 2020-04-23
WO2020081795A8 true WO2020081795A8 (en) 2020-07-09

Family

ID=70284254

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2019/056713 WO2020081795A1 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods

Country Status (3)

Country Link
AU (1) AU2019359878A1 (en)
CA (1) CA3116712A1 (en)
WO (1) WO2020081795A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111816315B (en) * 2020-05-28 2023-10-13 上海市生物医药技术研究院 Pancreatic duct cancer state assessment model construction method and application
EP4162434A1 (en) * 2020-06-04 2023-04-12 XCures, Inc. Methods and systems for precision oncology using a multilevel bayesian model
WO2023150285A1 (en) * 2022-02-04 2023-08-10 Elixirgen Therapeutics, Inc. Cell therapy protocol systems and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2245198A1 (en) * 2008-02-04 2010-11-03 Massachusetts Institute of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
US20150324527A1 (en) * 2013-03-15 2015-11-12 Northrop Grumman Systems Corporation Learning health systems and methods
US20140365242A1 (en) * 2013-06-07 2014-12-11 Siemens Medical Solutions Usa, Inc. Integration of Multiple Input Data Streams to Create Structured Data
US10642854B2 (en) 2016-10-07 2020-05-05 Sudeep Pattnaik Clinical data aggregation architecture and platform

Also Published As

Publication number Publication date
CA3116712A1 (en) 2020-04-23
WO2020081795A1 (en) 2020-04-23
AU2019359878A1 (en) 2021-05-27

Similar Documents

Publication Publication Date Title
Leguia et al. Seizure cycles in focal epilepsy
WO2020081795A8 (en) Data based cancer research and treatment systems and methods
Zeng et al. Meta-analysis of the efficacy of virtual reality–based interventions in cancer-related symptom management
CN104063824B (en) The generation method and device of health guidance information
CN107066814A (en) A kind of traditional Chinese medical science intelligent auxiliary diagnosis system cooperateed with based on the four methods of diagnosis
WO2002042876A3 (en) Systems and methods for integrating disease management into a physician workflow
Al Shobaili The pattern of skin diseases in the Qassim region of Saudi Arabia: What the primary care physician should know
Leonard et al. Direct cortical stimulation of inferior frontal cortex disrupts both speech and music production in highly trained musicians
Dijkstra et al. Identifying the attended speaker using electrocorticographic (ECoG) signals
CN109830302A (en) Medication mode excavation method, apparatus and electronic equipment
Ervin et al. High-gamma modulation language mapping with stereo-EEG: a novel analytic approach and diagnostic validation
WO2005067375A3 (en) Clinical data database system and method for a critical care and/or hospital environment
Johansen et al. Set-up errors in patients undergoing image guided radiation treatment. Relationship to body mass index and weight loss
CN109492885A (en) Medical insurance risk project analysis method device, terminal and readable medium
WO2024001695A1 (en) Data acquisition method, apparatus and system, and computer-readable storage medium
CN110164548A (en) A kind of physical examination system, equipment, storage medium and mobile terminal
Gage et al. Rethinking clinical language mapping approaches: discordant receptive and expressive hemispheric language dominance in epilepsy surgery candidates
Stephen et al. Multidipole analysis of simulated epileptic spikes with real background activity
Hermanns-Lê et al. Challenging regional psoriasis and ustekinumab biotherapy: impact of the patterns of disease
CN104887188A (en) Physical sign monitoring prompt and feedback system based on medical advice
Romoli et al. The validation of a new system of transcription of acupuncture points on the ear: The auricular sectogram
Reardon Obama to seek $215 million for precision medicine plan
Tsumoto et al. From hospital Big Data to clinical process: a granular computing approach
Hescheler Stem cells for regenerative medicine and anti-aging
Tiase et al. Navigating the Search for Patient Generated Health Data.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19873536

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 3116712

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2019873536

Country of ref document: EP

Effective date: 20210430

ENP Entry into the national phase

Ref document number: 2019359878

Country of ref document: AU

Date of ref document: 20191017

Kind code of ref document: A