WO2020039464A1

WO2020039464A1 - Bioresonance activated gel and uses in therapy thereof

Info

Publication number: WO2020039464A1
Application number: PCT/IT2019/050188
Authority: WO
Inventors: Mario Pastorelli
Original assignee: Mario Pastorelli
Priority date: 2018-08-23
Filing date: 2019-08-23
Publication date: 2020-02-27
Also published as: EP3840828A1

Abstract

Described is an electrically charged gel obtained through a process comprising or consisting of the following steps: a) putting a frequency generator apparatus into contact with said gel; and then b) emitting, by means of said frequency generator apparatus, one or more frequencies chosen from the group consisting of: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz and 117Hz, with a current within the order of μΑ, towards said gel, and a) removing said frequency generator apparatus from contact with said gel. Another object of the invention is an electrically charged gel for medical use, and for use in the treatment of at least one of the disorders chosen in the group consisting of: pain, osteoarticular diseases, postural problems, neurological and emotional osteoarticular problems, gonarthrosis, coxarthrosis, cervical arthrosis, lower back pains, lumbar spinal canal stenosis, cervical pain, tenosynovitis, shoulder pain, carpal tunnel, De Quervain's diseases, epicondylitis, ankle arthrosis, scoliosis, tendinitis, and muscle contractures.

Description

BIORESONANCE ACTIVATED GEL AND USES IN THERAPY

THEREOF

The present invention relates to a gel charged with specific frequencies, by means of a frequency generator apparatus, and its uses in therapy.

More in detail, the invention relates to a gel which is charged with specific frequencies and which, once applied, interacts positively with pain and posture receptors.

The field of application of the invention relates to energy medicine and the principles of bioresonance applied to postural re education and pain therapy, as well as the stimulation of the points in which acupuncture is normally applied.

The concept of frequencies and of cellular receptors for the frequencies is the basis of “quantum medicine” that is to say, medicine based on“quantum” physics.

In order to understand the transmission of the information through frequencies the example of the diapason is provided: if two diapasons are tuned to the same frequency, and if one of the two diapasons is resonated, the other also starts to vibrate. However, if we set the two diapasons on different frequencies, and one of the two is placed in resonance, the other will not vibrate even if the difference is just a very few Hertz.

As is well known, postural equilibrium is the result of a harmonious integration of afferents and efferents which have as an end result the correct motor coordination, both in static and dynamic terms. A correct posture sound proprioceptive, labyrinth and visual functions. The postural reactions depend above all on the proprioceptive information, and of extreme importance to the terms of the proprioception are the afferences starting from the feet, from the ligamentous capsule units, from neuromuscular spindles and from the Golgi tendon organs. All these afferents are essential for modulating the static and dynamic coordination, which is a prerequisite for correctly performing a movement. The sensitive-sensorial-motor system can be upset in terms of its harmony by insufficient or altered inputs and the final result can be a poor execution of a motor command. This can also occur in the presence of integrity of the projective paths, since the cortex and the white sub cortical substance, whilst processing a correct program, no longer receives an adequate feed-back from the periphery informing it that what was designed has been executed. This, obviously, also has considerable effects on the distribution of the muscular tone and on movement.

All this is extremely important for the wellbeing of any individual, but is even more important for a sportsperson, who stresses in a significant manner the muscular-skeletal system and for whom a minimum postural problem easily leads to the development of damage to tendons, ligaments, muscles orjoints.

Moreover, hundreds of observations have highlighted that, mainly in the patients with right or left convex scoliosis, the right half of the body is weak under the neuromuscular kinesiological tests, in particular for certain muscles of the shoulder and of the hip, whilst the extrinsics of the eye are weak to the left. This results in significant postural problems with disorder of the nerve roots and of the large joints.

It is also known that epicondylitis is an enthesopathy, that is, an affection of the tendinous insertion of the epicondyle outside the humeral bone from which the painful condition derives. Epicondylitis manifests itself with acute pain, sometimes disabling the individual, in the side region of the elbow and it affects persons of all ages. The risk factors can be due to working activities. The individuals most exposed are, for example, workers subjected to continuous vibrations, such as those deriving, for example, from the use of a pneumatic hammer; workers subjected to repetitive movements for rotation of the wrist, for example hairdressers, barmen, and workers who use a computer mouse or keyboard; sportsmen and women, for example tennis players.

The diagnosis of epicondylitis is based on a careful anamnesis and on the clinical recognition of the three main signs linked to tendinopathy: 1 ) with the elbow extended, the passive extension of the wrist is painful;

2) the active extension against resistance of the third finger with elbow and wrist extended results in the same symptoms;

3) the passive pressure at the level of the distal insertion of the extensor tendons of the finger is painful.

It is also known that osteoarthrosis consists in a process of deterioration of the cartilage and of the underlying subchondral bone; these phenomena result in, clinically, the gradual development of pain and the reduction of the articular function. The coxofemoral and femoral-tibial localisation of the arthrosis is particularly frequent. Pain relief is still a main objective in the treatment of patients who suffer from coxarthrosis.

Moreover, amongst the chronic disorders of the back bone there is the stenosis of the lumbosacral canal. Canal stenosis is a chronic disorder. The term “lumbar stenosis ” (from the Greek: stenosis : narrowing) means a reduction in the diameter of the vertebral canal, the side recess and/or the intervertebral foramina of the lumbosacral nerve roots, with consequent compression of the dural sac and/or of the spinal nerve roots. Lumbar stenosis has a clinical characterisation which varies in relation to the number of segments affected, their level, and the compromising, which is very often partial, of the spinal cord and of the nerve roots which are distributed from it on the periphery.

The main symptoms/signs are:

- pain;

- paraesthesia;

- motor claudication;

- hyposthenia of the lower limbs.

Depending on the seriousness of the symptoms, the treatment can either by surgical or conservative.

The surgical approach consists in the“decompression” of the vertebral-medullar canal, that is to say, that phase during which the surgeon, by removing certain predetermined bony segments (e.g. lamina, articular, foramen), restores the adequate space to the dural sac and to the structures contained therein, and then“stabilises” the rachis itself, that is to say, the phase during which, by using fixing devices such as transpedicular screws and titanium bars, the by now weakened rachis is reinforced and is once again made able to support the body weight during the daily activities of the patient.

The conservation approach consists in kinesitherapy, physical therapies (laser-therapy, TENS etc.), infiltrations. However, the conservative therapies have not currently been seen to significantly improve the symptoms complained of by the patients, nor give a long- lasting benefit.

In general, in order to resolve problems due to the above- mentioned disorders, use has been made for some time of kinesitherapy, pain killers, FANS, infiltrations of hyaluronic acid or cortisone, which are widely used and considered.

Currently, products are known for therapeutic use charged in bioresonance, that is to say, the CEM/TECH oscillators, which emit millimetric waves (radio waves), with frequencies of between 42.3GHz and 100GHz.

However, this type of systems are not able to adequately modulate the neuromuscular responses of the anti-gravitational chains and the fast and slow pain fibres and do not have any effect on the stature-postural chains.

Another neurological, and not mechanical, stimulation technique, aimed solely at resolving postural problems by stimulating the sole of the foot, is the bioresonance activated gel of Prof. Ricciardi. However, said activated gel does not have known working frequencies and only works for a few minutes, and must therefore be spread beneath the foot many times a day (approximately six).

In light of the above, there is an evident need for providing a device which is able to effectively modulate the neuromuscular responses of the anti-gravitational chains and of the fast and slow pain fibres, having importance on the stature-postural chains and on the nociceptive paths. This leads to the solution proposed according to the invention, which provides a bioresonance activated gel with specific frequencies, which is applied to some parts of the body for postural re-education and pain therapy, as well as for the stimulation of the points where acupuncture is normally applied.

Surprisingly, these frequencies, equal to 8Hz, 10Hz, 12Hz, 15Hz, 36Hz and 1 17Hz, are able to modulate the neuromuscular responses of the anti-gravitational chains and of the fast and slow pain fibres, interacting with the pain and posture receptors and having importance on the stature-postural chains and on the nociceptive paths. Moreover, frequencies have also been identified with a function, that is to say, the frequencies 26Hz and 30Hz. For this reason, the frequencies 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz and 1 17Hz are also able to modulate the neuromuscular responses of the anti-gravitational chains and of the fast and slow pain fibres, interacting with the pain and posture receptors and having importance on the stature-postural chains and on the nociceptive paths.

Specifically, the frequencies of 10Hz, 12Hz, 15Hz and 36Hz have been found to be effective for the treatment of postural problems but, more in particular, the frequencies 8Hz, 12Hz and 36 Hz have been found to be particularly effective for the treatment of postural problems. Moreover, in order to obtain an antalgic effect, the frequencies of 8Hz, 12Hz, 15Hz and 117Hz have been found to be effective and the frequencies of 8Hz, 12Hz, 26Hz and 30Hz have been found to be particularly effective. Lastly, the frequencies of 10Hz and 15Hz have been found to be effective in therapies replacing acupuncture.

These and other results are obtained according to the invention with a gel characterised by specific frequencies, transmitted in bioresonance through a pulse generator, with a very low intensity (microamperes), and applied in a specific point of the body, depending on the disorders presented.

The gel according to the invention is able to memorise the stresses to which it is subjected. In particular, the gel according to the invention is able to memorise frequencies which are transmitted to it by means of an electro-stimulation and to transmit them to the receptors of the human body. For this reason, by applying the gel according to the invention charged with predetermined frequencies on the skin, the passage of the electromagnetic charges to the human body will be obtained.

The gel according to the invention is charged in bioresonance through a bioresonance apparatus, or pulse or frequency generator apparatus, which is able to emit the selected frequencies so as to transmit them to the gel.

In particular, said bioresonance apparatus produces an electromagnetic field between two poles with frequencies which can vary from 0 (zero) to 127 (one hundred and twenty seven) Hz, is equipped with an ON/OFF switch and has a dip-switch comprising levers for selecting the desired frequencies. Said apparatus also comprises two frequency emitter electrodes. The activation in bioresonance of the gel, or charging of the gel, according to the invention is achieved by placing said emitters in contact with said gel, which transmit the set frequencies to the gel.

In particular, according to the invention, a gel, for example a normal gel for ultrasound purposes, is charged by placing it in contact, for a period of time of between approximately 15 minutes and 30 minutes, with the electrodes of a bioresonance apparatus producing frequencies of extremely low intensity (referred to as quantic energy), in particular the frequencies of 8Hz, 10Hz, 12Hz, 15Hz, 36Hz and 1 17Hz, and more preferably the frequencies of 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz and 1 17Hz.

The gel used can have various physical characteristics, varying the ratio between the solid part and the liquid part, and providing an aqueous or solid gel.

In particular, according to the invention, a liquid gel can be used, such as, for example, a normal gel for ultrasound purposes. Alternatively, according to the invention, a solid gel can also be used, such as, for example, the polyurethane gel, which can be obtained by mixing of polyol and isocyanate, the ratio of which can be varied to obtain a product with various characteristics. Due to its characteristics, the polyurethane gel is suitable in the cases in which a material is required which absorbs vibrations and impacts, or which provides comfort, and which is an extremely flexible material and with shape memory. The mechanical characteristics of an example of gel according to the invention are provided below, in particular sheets of polyurethane gel.

- Tensile strength (DIN 53504): 180 kPa

- Ultimate elongation (DIN 53504): 998%

- Tensile strength (after 168 hrs. at 70 °C) (DIN 53504): 132 kPa

- Ultimate elongation (after 168 hrs. at 70 °C) (DIN 53504): 995 kPa

- Applied density (DIN 53504): 1.03 kg/m3.

With regard to the bioresonance apparatus which, according to the invention, is used for charging the gel, as well as the apparatus 10 described in the drawing, apparatuses of the Bicom type, or Mora ® type can also be used.

Alternatively, a type of bioresonance apparatus designed to provide the charge, since it is able to mould water and gel in bioresonance, comprises a printed circuit (PCB) with two poles, like the devices described in patent application PCT/IT201 1/000225, which is able to emit electrical signals with intensity in the order of mA, with frequencies which can be selected by the operator, having a sinusoidal and/or square waveform, positive in both cases.

Lastly, a further type of bioresonance apparatus designed to provide the charge can consist of a circuit printed on soft material comprising a rigid central core, a microcontroller, a power supply unit, two electrodes with opposite polarity designed to generate a three-dimensional electric field, which is able to operate with currents between 14mA and 18mA, according to a waveform or a combination of waveforms in succession selected from: positive waves with trains of pulses with a rectangular shape, positive waves with trains of pulses with a sinusoidal shape, emitting at least one frequency or a combination of frequencies selected from 8Hz, 10Hz, 12Hz, 15Hz, 36Hz and 1 17Hz, or selected from 8Hz, 10Hz, 12Hz, 15Hz, 26 Hz, 30 Hz, 36Hz and 1 17Hz.

In particular, said bioresonance apparatus comprises a selection of 125 or 127 frequencies which vary from 1 Hz to 125Hz or 127 Hz.

When being charged, said gel is placed directly in contact with the electrodes of said bioresonance apparatus, for a variable period of time, which can be between 15 mins and 30 mins.

In this way an active gel is obtained which is able to maintain the frequencies received and, if then applied on the skin, to interact positively with the pain and posture receptors.

Again according to the invention, the gel can contain several frequencies inside it, which can vary depending on the disorders treated. For example, in the case of pain therapy, in which the treatment concerns muscular, skeletal and articular pains, as well as the frequencies used for the posture, it is worthwhile adding another specific frequency for the nociceptive fibres, which is active on the chronic and acute pains and is also specific for inflammation.

In the case of postural re-education, the gel according to the invention is placed, for example, on the medial vault of the foot, up to the inner malleolus, or on the palm face of the wrists, which are areas of the body not used until now by other apparatuses. These areas of the body in particular respond very well to treatment of postural problems, improving significantly and immediately an incorrect posture.

With regard to the duration over time of the treatment effectiveness of the device according to the invention, it has been noted that, after the activation of the gel by bioresonance, its effectiveness lasts, on average, for approximately three or four months. In this respect, again according to the invention, it was surprisingly found that, by adding piezoelectric powders to the gel, such as, for example, tachyonic powders, consisting of approximately 150 minerals, including, for example, tourmaline and quartz, the quantic energy transferred by the gel can be maintained on average from 18 months to 30 months, depending on the type of powders used. It has been noted, in fact, that the piezoelectric powders maintain the production of frequencies by the gel for a long time.

Moreover, again according to the invention, it was surprisingly found that, using the same frequencies, it is possible to activate, again with a bioresonance apparatus, small metal bodies, integrated circuits comprising an oscillator and soft and elastic silicon products, that is to say, elastic or rubbery silicone products. These activated materials have the same effectiveness as the gel, but with a duration of approximately 3 years.

The dimensions of said metal bodies can vary according to the use. For the postural problems, for example, metal conductors of just a few centimetres are sufficient, with dimensions comparable to a one euro coin, or less. Said metal bodies can usually be applied on the wrist, located inside a wristband, or on the feet, located inside an insole.

The charge of the metal bodies with said frequencies is obtained using the two generator poles of said bioresonance apparatus and leaving said metal bodies on charge for approximately 30 minutes.

The duration of the effectiveness of the aqueous gel, of the solid gel and of the metal bodies was evaluated through applied kinesiology muscular tests.

According to the invention, the gel can be applied in the following ways:

- if the gel is liquid, this can be sealed in small plastic containers, which can be applied in the sensitive areas of the human body with various supporting means, such as wrists, insoles and above all with sticking plasters, such as, for example, waterproof sticking plasters or anallergenic sticking plasters, created for the areas of the body;

- if the gel is solid, this can be applied directly on the skin and then covered with sticking plasters, such as, for example, waterproof sticking plasters or anallergenic sticking plasters, created for the areas of the body. The disorders treated successfully using the device according to the invention concern postural, osteoarticular, neurological and emotional problems.

The following tests were used to check the effectiveness of the treatment:

- R.O.M. (Range of Motion); and

- V.A.S. (Visual Analogue Scale).

In particular, the device has been seen to provide effective treatment in the cases of: gonarthrosis, coxarthrosis, lumbar spinal canal stenosis, cervical pain with significant functional limitation, shoulder pain, carpal tunnel, tenosynovitis, De Quervain’s diseases, epicondylitis, ankle arthrosis, tendinitis in general and muscle contractures.

Minimal and transient improvements were observed in two cases of cervical disc hernias in the acute phase. Moreover, use of the device was shown to be effectiveness in the treatment of juvenile scoliosis and in preventing, during the years of development, the increase in the degrees of the scoliotic curve.

Collaterally with the treatment of the osteoarticular disorders, it was observed that individuals who wore the protection noticed a clear improvement of the sleeping-waking rhythm, with better recovery during the night of the day efforts.

An aim of the invention is therefore to make a device in the form of bioresonance activated gel, with specific frequencies for each type of treatment, which is effective in the treatment of the above-mentioned disturbances and allows the limitations of the prior art solutions to be overcome.

A further aim of the invention is that said device can be made with substantially low costs, with regard both to the production costs and the management costs.

Yet another aim of the invention is to make a device which is substantially simple, safe and reliable. It is therefore a specific object of this invention an electrically charged gel obtained by means of a process of bioresonance activation comprising or consisting of the following steps:

a) putting a bioresonance apparatus into contact with said gel; and

b) transmitting to said gel, by means of said bioresonance apparatus, one or more frequencies chosen from the group consisting of 8Hz, 10Hz, 12Hz, 15Hz, 36Hz and 1 17Hz, or, more preferably, chosen from the group consisting of 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz and 1 17Hz, with a current within the order of mA, wherein said step b) can have a duration of between 15 and 30 minutes.

The gel according to the invention can comprises piezoelectric powders and can comprise an integrated circuit which is able to emit the above-mentioned signals; moreover, the gel according to the invention can be coated with a plastic casing, in particular if said gel is a liquid gel.

A further specific object of the invention is the gel as defined above for medical use.

Another object of the invention is the gel as defined above for use in the treatment of at least one of the disorders chosen in the group consisting of: pain, osteoarticular diseases, postural problems, neurological and emotional osteoarticular problems, gonarthrosis, coxarthrosis, cervical arthrosis, lower back pains, lumbar spinal canal stenosis, cervical pain, tenosynovitis, shoulder pain, carpal tunnel, De Quervain’s diseases, epicondylitis, ankle arthrosis, scoliosis, tendinitis, and muscle contractures.

Moreover, when the use of said gel is for the treatment of postural problems, said one or more frequencies can be chosen from the group consisting of 10Hz, 12Hz, 15Hz and 36Hz or, more preferably, from the group consisting of 8Hz, 12Hz and 36Hz.

Further, when the use of said gel is for the treatment of the pain, said one or more frequencies can be chosen from the group consisting of 8Hz, 12Hz, 15Hz, and 1 17Hz or, more preferably, from the group consisting of 8Hz, 12Hz, 26Hz, 30Hz and 1 17Hz. Lastly, when the use of said gel is for a treatment alternative to acupuncture, said one or more frequencies are chosen from the group consisting of: 10 Hz and 15 Hz.

A further object of the invention is an assembly comprising a casing, a gel according to the invention, said gel being included in said casing and a device comprising a circuit immersed in said gel, said circuit comprising an oscillator, in particular an oscillator for emitting electrical current pulses which are able to maintain the activation of the gel according to the invention.

In particular, said circuit, preferably a printed or integrated circuit, comprises an oscillator which can emit pulses with variable shape, which can be detected with a highly sensitive oscilloscope. The integrated circuit can be charged by placing it in an electromagnetic field which has the same characteristics as the three-dimensional field used for activating the gel, or for activating silicone products o metal bodies. Said integrated circuit, once activated with the method described, can be immersed in the gel, or in the silicone products.

In particular, said assembly can be coupled to sticking plasters, insoles or wrist bands to facilitate its application during the treatment of the above-mentioned conditions.

In fact, said device is advantageously able to maintain active the above-mentioned products for up to three years. The integrated circuit can be used only in combination with the gel to guarantee a more long- lasting effectiveness.

Moreover, said device can comprise a circuit printed on soft material comprising a rigid central core, a microcontroller, a power supply unit, two electrodes with opposite polarity adapted to generate a three- dimensional electric field, and can operate with currents between 14mA and 18mA, according to a waveform or a combination of waveforms in succession selected from: positive waves with trains of pulses with a rectangular shape, positive waves with trains of pulses with a sinusoidal shape, according to at least one frequency or combination of frequencies selected from: 8Hz, 10Hz, 12Hz, 15Hz e 36Hz, 1 17Hz, or also 26Hz and 30Hz.

Moreover, the power supply unit can be chosen from:

- a lithium battery, preferably 3 Volts;

- a rechargeable battery;

- a piezoelectric system with two peripheral accumulators; and

- a recharging system using solar energy.

Lastly, the device can alternatively be:

- integrated inside an insole;

- integrated inside a wristband; and

- integrated inside a sticking plaster.

The present invention is now described, by way of example and without limiting the scope of the invention, with reference to some examples and the accompanying drawings, in which:

- Figures 1A-1 C show three views of an apparatus for generating frequencies used for charging the gel according to the invention; and

- Figure 2 shows a perspective view of the apparatus of Figure 1 in contact with a gel according to the invention.

With reference to Figures 1 and 2, a frequency generator apparatus 10 according to the invention comprises a main switch 1 , designed to switch the device ON/OFF, a dip-switch 2 comprising frequency switches 3, designed to activate the emission of the corresponding frequency by the apparatus, a warning light 4, two electrodes 5 and a battery compartment 6.

With particular reference to Figure 2, according to the invention said electrodes 5 of said frequency generator apparatus 10 are positioned in contact with a gel 100. Said apparatus 10 is then switched on by means of the main switch 1 and the desired frequencies are set up by switching on respective frequency switches 3. In this way, said apparatus 10 transmits the selected sequences to said gel. Lastly, the apparatus 10 is switched off, using the main switch 1 , and the electrodes 5 are removed from said gel 100, so as to obtain a gel 100 electrically charged according to the invention.

The invention is now described, by way of example and without limiting the scope of the invention, with particular reference to some examples.

Example 1. Cervical arthrosis

1.1 First study on cervical arthrosis

Two patients were treated for two weeks at the physiotherapy practice of Dr. Claudio G. Campitelli (Castel Frentano, CH), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 36Hz, 117Hz.

The two patients, both male, were aged 67 and 81 , respectively.

Both complained of pain and cervical rigidity, in particular the first patient showed difficulty in turning the head to the right, whilst the second had difficulty in extending the head.

Both patients were assessed at their first visit before applying the gel (TO), 3 minutes after applying the gel (T1 ), a week later (T2) and after 45 days (T3).

The ROM (range of motion) values of the cervical rachis were assessed at each visit and the pain was assessed by means of the VAS scale.

The assessment of the articular ROM consisted in measuring the movements of the cervical rachis and in particular:

- bending: 70-90 degrees (measured by asking the patient to try to touch the breast bone with the chin);

- extension: 55 degrees (measured by asking the patient to try to point the chin towards the ceiling);

- side inclination: 35 degrees (measured by asking the patient to move the ear close to the shoulder); and - rotation: 70 degrees to the right and left (measured asking the patient to turn the head to the left and then to the right).

The device was applied locally to the patients by using a waterproof sticking plaster, in contact with the painful area for two weeks.

At TO a VAS was recorded for the first patient equal to 7, and a ROM value equal to 30%. At T 1 the same patient declared a VAS equal to 4 and the ROM had changed to 70%. At time T2 and T3 the data had improved further, with the VAS dropping, respectively, to values of 1 and 0, and the ROM values rising, respectively, to 80% and 90%.

Similarly, the following values were recorded for the second patient: TO: VAS 8, ROM 10%. T1 : VAS 6, ROM 50%. T2: VAS 3 ROM 70%. T3: VAS 1 , ROM 70%.

1.2 Second study on cervical arthrosis

Twelve patients were treated between January 2018 and April 2018 at the physical medicine clinic Diagnosi in Tempo (Sesto Fiorentino, FI), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz, 1 17Hz.

All the patients were affected by cervical pain caused by multiple discopathy and arthrosis and were treated with a strip of activated gel by means of a sticking plaster applied on the mid-cervical region.

The patients were assessed at their first visit before applying the gel (TO), 15 days later (T1 ) and 30 days after the first application of the gel (T2).

The cervical ROM values were assessed at each visit and the pain was assessed by means of the VAS scale.

The average VAS at TO was equal to 7, the average cervical ROM was equal to 50%.

The average VAS at T 1 had dropped to 4, the average cervical ROM had risen to 70%.

During the last control visit, at T2, the average VAS was 2 and the average cervical ROM had reached 90%. Example 2. Lumbalgia

2.1 First study on lumbalgia

Six patients with acute lumbalgia were treated for 2 weeks at the physiotherapy practice of Dr. Claudio G. Campitelli (Castel Frentano, CH), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz, 117Hz.

The patients were assessed at their first visit before applying the gel (TO), 3 minutes after applying the gel (T1 ), a week later (T2) and after 45 days (T3).

The ROM (range of motion) values were assessed at each visit; the pain was also assessed by means of the VAS scale.

The assessment of the articular ROM consisted in measuring the movements of the lumbar rachis and in particular the bending, the extension and the rotation.

The device was applied locally to the patients by using a waterproof sticking plaster, in contact with the area of the painful vertebra

Table 1 shows the results obtained:

Table 1

2.2 Second study on umbalgia

Twenty five patients were treated between November 2017 and May 2018 at the physical medicine clinic Diagnosi in Tempo (Sesto Fiorentino, FI), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Flz, 10Hz, 12Hz, 15Hz, 26Flz, 30Flz, 36Flz, 117Hz.

All the patients suffered from chronic backache and limited autonomy of movement, with diagnosis of lumbar stenosis due to degenerative arthrosis and were treated with the gel activated electrically applied on the lumbar region by means of a sticking plaster.

The patients were assessed at their first visit before applying the gel (TO), a week later (T 1 ) and after 30 days (T2).

The pain was assessed at each visit by means of the VAS scale.

At the initial visit (TO) the average VAS was 8, the average movement autonomy was 500 m.

The patients were reassessed after a week (T1 ): the average VAS at T1 was 4 and all the patients said they had greater autonomy of movement and a shorter recovery time after the effort. These results were maintained after a month (T2).

Example 3. Shoulder pain

3.1 First study on shoulder pain

Eight patients with shoulder pain were treated for 2 weeks at the physiotherapy practice of Dr. Claudio G. Campitelli (Castel Frentano, CFI), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Flz, 10Hz, 12Hz, 15Hz, 26Flz, 30Flz, 36Flz, 1 17Hz. The patients were assessed at their first visit before applying the gel (TO), 3 minutes after applying the gel (T1 ), a week later (T2) and after 45 days (T3).

The ROM (range of motion) values were assessed at each visit and the pain was assessed by means of the VAS scale.

The assessment of the ROM for the shoulder pain consisted in measuring the movements of the arm and in particular the bending and the abduction.

The device was applied locally to the patients by using a waterproof sticking plaster, in contact with the painful area.

Table 2 shows the results obtained:

Table 2

3.2 Second study on shoulder pain Nine patients were treated between November 2017 and May 2018 at the physical medicine clinic Diagnosi in Tempo (Sesto Fiorentino, FI), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz, 1 17Hz.

All the patients suffered from back pain due to chronic tendinopathy of the rotator cuffs without continuous lesions of the tendons and were treated with the gel activated electrically applied at the glenohumeral joints by means of a sticking plaster.

The patients were assessed at their first visit before applying the gel (TO), a week later (T 1 ) and after 15 days (T2).

The ROM values were assessed at each visit and the pain was assessed by means of the VAS scale.

The assessment of the ROM for the shoulder pain consisted in measuring the movements of the arm and in particular the bending and the abduction. During the initial visit the average VAS was 8, the patients complained of significant pain also at night and limitations in the movements. The articular ROM value was on average equal to 60%.

At visit T1 the patients said they were able to sleep at night and the average VAS was equal to 4. The articular ROM value was on average equal to 90%.

At visit T2 the average VAS was 2 and the articular ROM value was on average equal to 90%.

Example 4. Gonarthrosis and coxarthrosis

Fifteen patients were treated between November 2017 and April 2018 at the physical medicine clinic Diagnosi in Tempo (Sesto Fiorentino, FI), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Flz, 10Hz, 12Hz, 15Hz, 26Flz, 30Flz, 36Flz, 117Hz.

Seven patients suffered from slight-moderate gonarthrosis, whilst eight patients suffered from slight-moderate coxarthrosis. The ROM (range of motion) values were assessed at each visit, and the pain was assessed by means of the VAS scale.

The assessment of the ROM for the gonarthrosis and the coxarthrosis consisted in measuring, respectively, the movements of the leg and the thigh and in particular the bending and the extension.

All the patients during the initial visit mentioned pain and limitation of movements, in particular the average VAS was equal to 7 and the average articular ROM value was 50%.

A sticking plaster with the activated gel was applied on the medial joint for patients suffering from gonarthrosis, whilst for patients suffering from coxarthrosis the sticking plaster with the activated gel was applied on the inguinal fold.

All the patients were reassessed after a week, and the average VAS had dropped to 3, whilst the average ROM had risen to 70%.

A second and last visit was carried out 30 days after application of the gel, during which the average VAS media had dropped further to 1 , whilst the average ROM value was stable at 70%.

Example 5. Epicondylitis

Three patients were treated for two weeks at the physiotherapy practice of Dr. Claudio G. Campitelli (Castel Frentano, CH), with the gel electrically charged according to the invention, charged in bioresonance, that is to say, charged by means of a frequency generator apparatus or a bioresonance apparatus, with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz, 1 17Hz.

The three patients, two female and one male, were aged between 35 and 59.

All the patients demonstrated an initial difficulty in extending the hand, which was assessed at their first visit, before applying the gel (TO), 3 minutes after applying the gel (T1 ), a week later (T2) and after 45 days (T3). The ROM (range of motion) values of the hand were recorded at each visit and the pain was assessed by means of the VAS scale.

The assessment of the ROM for the epicondylitis consisted in measuring the movements of the forearm and in particular the bending and the extension.

The activated gel was applied locally to the patients by using a waterproof sticking plaster, in contact with the painful area.

The values recorded for the individual patients are shown in

Table 3.

At TO the average VAS was equal to 8.7 and the average ROM recorded was equal to 43%.

At T1 the average VAS had dropped to 4.7, whilst the average ROM was equal to 77%.

At T2 and T3 the average values of VAS and ROM had further improved, with the average VAS equal, respectively, to 1.7 and 0.3 and the average ROM equal, respectively, to 93% and 100%.

Table 3

Example 6. Study on the effectiveness of the gel at the practice of Dr. Elvis Lela

Thirty one patients, of whom eighteen female and thirteen male, aged between 32 and 71 , were treated with electrically charged gel according to the invention at the practice of Dr. Elvis Lela.

The patients suffered from various disorders; more specifically: ten patients suffered from backache (four with acute backache and six with chronic backache); six patients suffered from cervical pain (three with acute cervical pain and three with chronic cervical pain); five patients suffered from gonarthrosis; eight patients suffered from shoulder pain; and two suffered from epicondylitis.

All the patients were asked not to take pain-killing or anti inflammatory drugs during the 12 hours prior to the visit.

The patients were assessed at their first visit before applying the gel (TO), three minutes later (T1 ), a week later (T2) and after 45 days (T3).

The ROM values were assessed at each visit and the pain was assessed by means of the VAS scale. The ROM values were assessed for each disorder described in the previous examples.

The data obtained from these measurements is shown in Table 4.

Table 4

A clear improvement of the pain measured with the VAS scale was observed during the assessment.

The patients carried out the test movements more easily and without limitations with a clear increase in the ROM, with the exception of the cases of epicondylitis for which the ROM remained constant.

Example 7. Tenosynovitis

Tenosynovitis, or “lock finger”, is a disorder linked to the synovial sheath of the tendons which can result in swelling or rigidity of the finger, localised pain on the palm of the hand, and having the finger locked in a bent position, which then straightens suddenly or, in more serious cases, having a finger which is not able to complete the extension movement.

Two patients affected by this disorder were treated for two weeks at the physiotherapy practice of Dr. Claudio G. Campitelli (Castel Frentano, CH), with the gel electrically charged according to the invention, charged in bioresonance with the following frequencies: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz, 1 17Hz.

The two patients, both male, were aged 56 and 58, respectively.

Both complained of difficulty in extending the finger.

The ROM (range of motion) values relative to the extension of the finger were assessed at each visit, and the pain was assessed by means of the VAS scale.

At TO a VAS was recorded for the first patient equal to 9, and a ROM value equal to 20%. At T 1 the same patient declared a VAS equal to 7 and the ROM had changed to 30%. At time T2 and T3 the data had improved further, with the VAS dropping, respectively, to values of 3 and 1 , and the ROM value was in both cases equal to 90%. Similarly, the following values were recorded for the second patient: TO: VAS 8, ROM 70%. T1 : VAS 5, ROM 80%. T2: VAS 2 ROM 90%. T3: VAS 1 , ROM 90%.

The present invention is described by way of example only, without limiting the scope of application, according to its preferred embodiments, but it shall be understood that the invention may be modified and/or adapted by experts in the field without thereby departing from the scope of the inventive concept, as defined in the claims herein.

Claims

1 ) Electrically charged gel obtained through a process comprising or consisting of the following steps:

a) putting a frequency generator apparatus into contact with said gel; then

b) emitting, by means of said frequency generator apparatus, one or more frequencies chosen from the group consisting of: 8Hz, 10Hz, 12Hz, 15Hz, 26Hz, 30Hz, 36Hz and 1 17Hz, with a current within the order of mA, towards said gel, and then

a) removing said frequency generator apparatus from contact with said gel.

2) Gel according to claim 1 , wherein said one or more frequencies are chosen from the group consisting of: 8Hz, 10Hz, 12Hz, 15Hz, 36Hz and 1 17Hz.

3) Gel according to any one of the preceding claims, wherein said gel comprises piezoelectric powders.

4) Gel according to any one of the preceding claims, wherein said step b) has a duration of between 15 and 30 minutes.

5) Gel according to any one of the preceding claims, wherein, after said step c), said gel is sealed inside a plastic casing.

6) Gel as defined in anyone of the preceding claims for medical use.

7) Gel as defined in anyone of claims 1 to 5 for use in the treatment of at least one of the disorders chosen in the group consisting of: pain, osteoarticular diseases, postural problems, neurological and emotional osteoarticular problems, gonarthrosis, coxarthrosis, cervical arthrosis, lumbalgia, lumbar canal stenosis, cervical pain, tenosynovitis, shoulder pain, carpal tunnel, De Quervain’s diseases, epicondylitis, ankle arthrosis, scoliosis, tendinitis, and muscle contractures.

8) Gel as defined in anyone of claims 1 to 5, for use according to claim 7, wherein when the use is for the treatment of postural problems, said one or more frequencies are chosen from the group consisting of 8Hz, 12Hz and 36Hz or from the group consisting of 10Hz, 12Hz, 15Hz and 36Hz.

9) Gel as defined in anyone of claims 1 to 5, for use according to claim 7, wherein when the use is for the treatment of the pain, said one or more frequencies are chosen from the group consisting of 8Hz, 12Hz, 26Hz, 30Hz and 1 17Hz or from the group consisting of 8Hz, 12Hz, 15Hz and 1 17Hz.

10) Gel according to any one of claims 1 to 5, for use according to claim 7, wherein when the use is for a treatment alternative to acupuncture, said one or more frequencies are chosen from the group consisting of 10Hz and 15Hz.

1 1 ) An assembly comprising a casing, a gel according to any one of claims 1 to 4 included in said casing and a device comprising a circuit immersed in said gel, said circuit comprising an oscillator.