WO2019225204A1 - Radiographic device, radiographic system, radiographic method, and program - Google Patents

Radiographic device, radiographic system, radiographic method, and program Download PDF

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Publication number
WO2019225204A1
WO2019225204A1 PCT/JP2019/015985 JP2019015985W WO2019225204A1 WO 2019225204 A1 WO2019225204 A1 WO 2019225204A1 JP 2019015985 W JP2019015985 W JP 2019015985W WO 2019225204 A1 WO2019225204 A1 WO 2019225204A1
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image
frame
substance
statistical information
display
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PCT/JP2019/015985
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French (fr)
Japanese (ja)
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広紀 須田
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キヤノン株式会社
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment

Definitions

  • the present invention relates to a radiation imaging apparatus, a radiation imaging system, a radiation imaging method, and a program.
  • Patent Document 1 a frame to be stored in a radiographic image (for example, a frame in which a contrast medium is reflected in an examination using a contrast medium) is automatically extracted based on a change in pixel information at a specific position.
  • the luminance is high because it is originally high or because a substance of interest such as a contrast medium is reflected. It may not be possible to determine.
  • the present invention provides a technique capable of extracting a frame containing a target substance.
  • the radiographic apparatus includes a generation unit that generates a substance identification image indicating a distribution of a plurality of substances included in a radiographic image captured with different radiation energies, Extraction means for obtaining statistical information on a specific substance for each frame constituting the substance identification image and extracting a frame based on the statistical information.
  • the accompanying drawings are included in the specification, constitute a part thereof, show an embodiment of the present invention, and are used to explain the principle of the present invention together with the description.
  • the figure which illustrates the effective atomic number of a substance. The figure which illustrates the correspondence of the attenuation coefficient (mass attenuation coefficient) of each substance and the energy component of a radiation.
  • the figure explaining the determination method of the extraction range of the frame in 2nd Embodiment The figure which illustrates the functional structure of the radiography system in 3rd Embodiment.
  • the radiation includes ⁇ rays, ⁇ rays, ⁇ rays, and various particle rays in addition to X-rays.
  • a radiation imaging system that includes a radiation generation device and a radiation imaging device and can generate an energy subtraction image will be described.
  • moving image capturing will be described as an example of capturing a radiation image.
  • FIG. 1 is a diagram illustrating a functional configuration of the radiation imaging system 100 according to the first embodiment.
  • the radiation imaging system includes a radiation generator 11 and a radiation imaging apparatus 10.
  • the radiation imaging apparatus 10 of the radiation imaging system 100 When imaging by the energy subtraction method is performed, a plurality of radiographic images captured with different radiation energies are required to generate one subtraction image.
  • the radiation imaging apparatus 10 of the radiation imaging system 100 performs sampling a plurality of times during one frame imaging period, An image by high energy radiation (high energy image) and an image by low energy radiation (low energy image) are generated. Thereby, the radiation imaging apparatus 10 can acquire a plurality of energy images, for example, a high energy image and a low energy image for each frame in one frame period.
  • the radiation imaging apparatus 10 of the present embodiment includes a radiation imaging unit 101, an image acquisition unit 102, a substance decomposition unit 103, an image generation unit 104, a frame extraction unit 105, an image communication unit 106, and a display control unit 107 as functional configurations. .
  • the radiation imaging unit 101 includes, for example, a flat panel detector (FPD), and receives radiation irradiated from the radiation generation apparatus 11 and captures a radiation image as radiation energy intensity distribution information. .
  • FPD flat panel detector
  • the radiation imaging unit 101 When receiving an imaging start instruction from the display control unit 107 having a user interface (UI), the radiation imaging unit 101 receives radiation irradiated at a predetermined interval by the radiation generation device 11 and captures a radiation image.
  • UI user interface
  • the radiation imaging unit 101 can accumulate a plurality of pieces of radiation distribution information based on the radiation emitted from the radiation generator 11. For example, by controlling the sampling hold signal, the radiation distribution information (XL) accumulated during the first sampling time from the start of radiation irradiation is sampled and held, and accumulated during the second sampling time longer than the first sampling time. The received radiation distribution information (XH) is sampled and held.
  • the radiation distribution information (XL) accumulated during the first sampling time from the start of radiation irradiation is sampled and held, and accumulated during the second sampling time longer than the first sampling time.
  • the received radiation distribution information (XH) is sampled and held.
  • the energy XL is radiation energy lower than the energy XH and is used to generate a low energy image
  • the energy XH is used to generate a high energy image.
  • a plurality of energy images, for example, a high energy image and a low energy image can be acquired for each frame by performing sampling a plurality of times during one frame shooting period.
  • the radiation imaging unit 101 captures, for example, a high energy image and a low energy image as a plurality of energy images for each frame, and the captured radiation image (low energy) Image, high energy image) is output to the image acquisition unit 102.
  • the image acquisition unit 102 acquires the radiation image generated by the radiation imaging unit 101 for each image. For example, when radiography is performed with two different radiation energies, a high energy image and a low energy image are acquired for generating one frame, and the acquired images (a high energy image and a low energy image) are subjected to material decomposition. Output to the unit 103.
  • the substance decomposing unit 103 uses the energy subtraction method to extract two from the high energy image 21 and the low energy image 22.
  • the effective atomic number and areal density can be obtained by establishing an equation and finding the solution.
  • the effective atomic number indicates the atomic number corresponding to the average of the constituent elements of an element, compound, or mixture, and the atomic number of a hypothetical element that attenuates photons at the same rate as that substance. It is the quantitative index shown.
  • FIG. 3A is a diagram illustrating an effective atomic number (data table) of a substance used for generating a substance identification image in the substance decomposing unit 103.
  • FIG. 3B is a diagram illustrating the correspondence (data diagram) between the attenuation coefficient (mass attenuation coefficient) of each substance and the energy component (single wavelength) of radiation.
  • Information indicating the correspondence relationship (data table, data diagram) of FIGS. 3A and 3B is stored in advance in the storage unit 109 (internal memory) of the radiation imaging apparatus 10, and the material discrimination process of the energy subtraction method is executed. In doing so, the substance can be discriminated by referring to the data table of FIG. 3A.
  • the substance decomposing unit 103 (generating unit) generates a substance identification image indicating distributions of a plurality of substances included in radiographic images taken with different radiation energies.
  • the substance decomposition unit 103 generates a substance identification image indicating the distribution of the specific substance corresponding to the effective atomic number from the effective atomic number and the surface density acquired by the substance discrimination process of the energy subtraction method, and the generated substance identification image is displayed as an image.
  • the data is output to the generation unit 104 and the frame extraction unit 105.
  • the substance identification image may be generated based on the effective atomic number or the surface density of the substance.
  • the image generation unit 104 generates a diagnostic image based on the substance identification image. That is, the image generation unit 104 generates a display processing image (diagnosis image) based on the substance identification image generated for each of the plurality of substances.
  • the image generation unit 104 generates, as a display processing image (diagnostic image), an image that emphasizes a specific substance among a plurality of substances based on one energy component of radiation.
  • the display processing image includes a virtual monochromatic radiation image described below.
  • the radiation irradiated from the radiation generator 11 includes a plurality of energy components
  • the image generation unit 104 includes a radiation image (virtual monochromatic radiation image) based on any one of the plurality of energy components. Is generated based on the substance identification image.
  • the attenuation coefficient of each substance corresponding to the selected energy component (single wavelength) can be obtained from the data diagram of FIG. 3B. Since the attenuation coefficient of the substance corresponding to each energy component of radiation is known (FIG. 3B), the pixel value distribution in an arbitrary energy component can be obtained by combining the known attenuation coefficient and the acquired substance identification image. Is required.
  • the image generation part 104 can generate
  • the energy component for generating the virtual monochromatic radiation image can be arbitrarily selected.
  • the image generation unit 104 combines the attenuation coefficient corresponding to the energy component set by the operator and the substance identification image. Thus, it is possible to acquire the distribution of pixel values in the set energy component and generate it as a diagnostic image (virtual monochromatic radiation image).
  • the diagnostic material emphasizes the specific material identified by creating a monochromatic radiation image of the energy component that maximizes the radiation absorption rate of the specific material. Images can be generated. Based on the data diagram of FIG. 3B, an attenuation coefficient corresponding to an energy component that emphasizes the specific substance is acquired, and the specific substance is emphasized by combining the acquired attenuation coefficient and the substance identification image. The distribution of pixel values in the energy component can be acquired and generated as a diagnostic image (virtual monochromatic radiation image).
  • the storage unit 109 internal memory of the radiation imaging apparatus 10
  • information indicating the correspondence (data table, data diagram) of FIGS. 3A and 3B is stored, and the data table (FIG. 3A) is stored in the substance discrimination processing.
  • Each substance can be discriminated by referring to it, and a virtual monochromatic radiation image corresponding to an arbitrary energy component can be generated by referring to a data diagram (see FIG. 3B).
  • the substance decomposition unit 103 and the image generation unit 104 acquire the correspondence relationship between the data table and the data diagram through communication with an external device via the image communication unit 106, and identify the substance discrimination and virtual monochromatic radiation image. It is also possible to generate.
  • the diagnostic image is not limited to the virtual monochromatic radiation image, and the image generation unit 104 generates an image (average energy image) obtained by averaging the pixel values of the high energy image and the low energy image described above as the diagnostic image. It is also possible.
  • the image generation unit 104 outputs the generated diagnostic image (virtual monochromatic radiation image or average energy image) to the display control unit 107.
  • the frame extraction unit 105 obtains statistical information about a specific substance for each frame constituting the substance identification image, and extracts a frame based on the statistical information. For example, the frame extraction unit 105 obtains statistical information (for example, the content rate of each substance) indicating the ratio of a specific substance for each frame constituting the substance identification image, The extracted image is generated by extracting the frame to be obtained from the frame constituting the display processing image generated based on the substance identification image. The frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
  • statistical information for example, the content rate of each substance
  • the extracted image is generated by extracting the frame to be obtained from the frame constituting the display processing image generated based on the substance identification image.
  • the frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
  • the ratio (content ratio) that the substance specified by the effective atomic number occupies the frame may be obtained.
  • the frame extraction unit 105 acquires statistical information used for frame extraction based on the substance identification image, and extracts a frame from the diagnostic image (virtual monochromatic radiation image or average energy image) based on the acquired statistical information. .
  • the frame extraction unit 105 acquires, for example, pixel value information indicating luminance and density from the substance identification image acquired from the substance decomposition unit 103 as statistical information, and compares the statistical information with a threshold value to determine the specified substance.
  • a frame including statistical information equal to or greater than a threshold is specified.
  • the frame extraction unit 105 extracts a frame having the same frame number as the frame specified based on the substance identification image from the diagnostic image (virtual monochromatic radiation image or average energy image) acquired from the image generation unit 104. Extract and generate a multi-frame image defined by DICOM (Digital Imaging and COmmunications in Medicine) as a DICOM image.
  • the frame extraction unit 105 uses a DICOM image (based on the DICOM standard) based on an extracted image extracted from a frame that constitutes a display processing image generated based on the substance identification image. Saved image).
  • the frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
  • the image communication unit 106 is configured to be able to communicate with an external device via a network.
  • the frame information extracted by the frame extraction unit 105 and the generated DICOM image are transferred to a PACS (Picture Archive Communication System) 12. Send.
  • PACS Picture Archive Communication System
  • the image communication unit 106 acquires the DICOM image extracted from the frame extraction unit 105 and conforms to the DICOM standard. Is transmitted to the PACS 12 using the protocol described above.
  • the image communication unit 106 can also transmit information about the subject, imaging conditions, and the like to the PACS 12 as supplementary information of the DICOM image.
  • the PACS 12 can receive and store the DICOM image file from the image communication unit 106 and display the DICOM image for diagnosis.
  • the data amount at the time of storage is saved, and pixel information (for example, luminance) at a specific position is saved. It is possible to accurately extract a frame in which a substance of interest in a radiographic image is included in a radiation image at a threshold value or more, regardless of the measurement result of the change in the pixel value such as the density and the pixel value.
  • the display control unit 107 performs display control for displaying a radiation image on the display unit.
  • the display control unit 107 receives a generation notification indicating completion of image generation for the diagnostic image from the image generation unit 104, the display control unit 107 displays the diagnostic image (virtual monochromatic radiation image) from the image generation unit 104. Or an average energy image) is acquired and displayed on the display unit.
  • the display unit may be provided as a configuration of the radiation imaging apparatus 10 or may be an external configuration of the radiation imaging apparatus 10.
  • FIG. 2 is a sequence diagram showing a flow of processing from the radiographic image capturing to the generation of an image (DICOM image) corresponding to the DICOM standard in the first embodiment.
  • a plurality of different energy images captured by the radiation imaging unit 101 are decomposed into a plurality of substance identification images, and a diagnostic image (in this example, a virtual monochromatic radiation image) is generated and output to the PACS 12.
  • a diagnostic image in this example, a virtual monochromatic radiation image
  • step S201 the radiation imaging unit 101 captures the high energy image 21 and the low energy image 22 as a plurality of energy images for each frame in order to generate one frame of the radiation image, and the captured high energy image 21 and The low energy image 22 is output to the image acquisition unit 102.
  • step S ⁇ b> 202 the image acquisition unit 102 acquires the high energy image 21 and the low energy image 22 captured by the radiation imaging unit 101, and outputs the acquired plurality of energy images to the substance decomposition unit 103.
  • the substance decomposition unit 103 generates a substance identification image from the high energy image 21 and the low energy image 22 by the energy subtraction method.
  • the substance decomposing unit 103 includes a substance identification image for each substance constituting the human body such as water, bone, and fat (hereinafter, the substance identification image for each substance is collectively referred to as “human body density image 23”), blood vessel A substance identification image (for example, a contrast medium density image 24) is generated for the contrast medium injected into.
  • the human body density image 23 and the contrast medium density image 24 are used in the display process 2001 and the frame extraction process 2002.
  • display processing 2001 is processing for generating a diagnostic image based on the substance identification image and displaying the generated image.
  • the frame extraction process 2002 is a process for extracting a frame including a specific substance based on the substance identification image and generating a DICOM image based on the extracted frame.
  • step S ⁇ b> 204 of the display process 2001 the substance decomposition unit 103 outputs the generated human body density image 23 and the contrast agent density image 24 to the image generation unit 104.
  • step S205 the image generation unit 104 generates a virtual monochromatic radiation image 25 as a diagnostic image. If the high energy image 21 and the low energy image 22 are discriminated into a human body density image 23 and a contrast medium density image 24 which are substance identification images, the effective atomic number and attenuation coefficient of each substance and contrast medium constituting the human body are known. Therefore, the virtual monochromatic radiation image 25 can be generated for the radiation energy component (single wavelength) corresponding to the attenuation coefficient.
  • step S206 the image generation unit 104 notifies the display control unit 107 of image generation.
  • the image generation unit 104 outputs a generation notification indicating the completion of image generation to the display control unit 107.
  • step S207 the display control unit 107 acquires the virtual monochromatic radiation image 25 from the image generation unit 104 and displays it.
  • the display control unit 107 displays a diagnostic image (virtual monochromatic radiation image, Alternatively, an average energy image) is acquired and displayed on the display unit.
  • step S208 of the frame extraction process 2002 the substance decomposing unit 103 transmits the generated substance identification image (for example, the human body density image 23 and the contrast agent density image 24) to the frame extracting unit 105.
  • the generated substance identification image for example, the human body density image 23 and the contrast agent density image 24
  • step S209 the frame extraction unit 105 executes a frame extraction process.
  • the frame extraction unit 105 acquires statistical information used for frame extraction based on the substance identification image, and extracts a frame based on the acquired statistical information.
  • the frame extraction unit 105 identifies a frame in which the statistical information of the designated substance is included in the threshold value or more by comparing the statistical information acquired from the substance identification image with the threshold value.
  • the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 from the image generation unit 104 and creates a DICOM image.
  • the frame extraction unit 105 acquires a frame having the same frame number as the frame identified based on the substance identification image from a diagnostic image (for example, a virtual monochromatic radiation image) acquired from the image generation unit 104, and is defined by DICOM.
  • the generated multi-frame image is generated as a DICOM image.
  • FIG. 4 is a diagram showing a flow of the frame extraction process 2002 of the frame extraction unit 105 in the first embodiment.
  • the substance decomposition unit 103 transmits the generated substance identification image (the human body density image 23 and the contrast medium density image 24) to the frame extraction unit 105, and the frame extraction unit 105 performs a frame extraction process according to the following processing flow.
  • the frame extraction unit 105 measures how much substance to be extracted is included for each frame from the substance identification image obtained from the substance decomposition unit 103. Specifically, the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation.
  • the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0. The total pixel value in the frame also increases as the amount of the substance is increased. That is, the pixel value of the frame of the substance identification image increases as the substance is included in the frame.
  • the frame extraction unit 105 obtains, as statistical information, the result of dividing the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation from the substance identification image by the number of pixels of the irradiation field for each frame. get.
  • the frame extraction unit 105 divides the total pixel value in the frame obtained in step S401 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. By calculating the content ratio divided by the number of pixels in the irradiation field without directly handling the total number of pixels, it is possible to cope with cases where the resolution of the radiation imaging unit 101 is different.
  • the frame extraction unit 105 compares a specified substance, for example, statistical information such as a contrast agent, with a threshold value, and includes a frame that includes the statistical information of the specified substance at a threshold value or more. Identify.
  • the frame extraction unit 105 extracts a frame in which the content rate of the substance is included in a certain threshold or more, and sets a range determined by a series of frames included in the certain threshold or more as a frame extraction range.
  • the frame extraction unit 105 generates a frame list of the extraction range based on the frames included in the extraction range.
  • step S404 the frame extraction unit 105 acquires a display processing image generated based on the substance identification image.
  • the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
  • the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame list of the extraction range generated in step S403, and creates a multi-frame image defined by DICOM for each extraction range. Generated as a DICOM image.
  • the frame list of the extraction range includes frame number information in the radiographic image as frame information for specifying the frame, and the frame extraction unit 105 has the same frame number as the frame specified based on the substance identification image. Is acquired from a diagnostic image (virtual monochromatic radiation image), and a DICOM image is generated based on the acquired frame. For example, if there are a plurality of extraction ranges in the radiographic image, the frame extraction unit 105 generates a plurality of DICOM images for each extraction range.
  • the frame extraction unit 105 stores the radiation image and index information indicating the extraction range for each substance with respect to the radiation image in the storage unit 109 in combination.
  • index information it is possible to search a range in which a frame is extracted for each substance in a radiographic image and regenerate a diagnostic image based on the radiographic image stored in the storage unit 109. Become.
  • FIG. 5 is a diagram for explaining a frame extraction range determination method in step S403 in FIG.
  • the horizontal axis represents time, and the content rate of the substance to be extracted in each frame is indicated by hatching.
  • the frame 501 indicates that the content rate of the substance to be extracted is equal to or greater than a threshold value.
  • the frame extraction unit 105 extracts a frame including statistical information that is greater than or equal to a certain threshold value from the frames constituting the substance identification image, and sets a series of frames that are equal to or greater than the threshold value as an extraction range. Then, the frame extraction unit 105 extracts a frame corresponding to the extraction range from the frames constituting the display processing image. First, the frame extraction unit 105 identifies a frame in which the statistical information of the substance (the content rate of the substance to be extracted) is included more than a threshold. The frame extraction unit 105 extracts a frame in which the content rate of the substance is equal to or greater than a certain threshold, and sets a series of frames that are equal to or greater than the threshold as an extraction range.
  • the extraction range 502 and the extraction range 503 are extracted, and the frame extraction unit 105 generates and holds a frame list of the extraction range based on the frames included in the extraction range. To do. Frames that do not exceed the threshold are not extracted.
  • the present embodiment it is possible to extract a frame containing a material of interest in a radiographic image.
  • material discrimination technology of the energy subtraction method statistical information (content ratio of the extraction target substance) of the specified substance is acquired for each frame, and frames above the threshold are extracted and extracted as frames necessary for diagnosis.
  • the data amount at the time of storage is saved, and the measurement result of changes in pixel information (for example, pixel values such as luminance and density) at a specific position is saved. Regardless, it is possible to accurately extract a frame in which a target substance is included in the radiographic image for a threshold value or more.
  • a series of frames including the statistical information of substances (content ratio of substances to be extracted) equal to or more than a threshold is specified as the extraction range.
  • a configuration in which the range defined by the first frame and the last frame in which the statistical information of the substance (content ratio of the substance to be extracted) is equal to or greater than the threshold is specified as the extraction range will be described.
  • FIG. 6 is a diagram illustrating a flow of the frame extraction process 2002 of the frame extraction unit 105 in the second embodiment, and the frame extraction process 2002 is a process corresponding to the process sequence described in FIG. 2 of the first embodiment.
  • the frame extraction unit 105 measures how much of the substance to be extracted is included for each frame from the substance identification image obtained from the substance decomposition unit 103.
  • the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation.
  • the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0.
  • step S602 the frame extraction unit 105 divides the sum of the pixel values in the frame obtained in step S601 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. .
  • the frame extraction unit 105 includes the statistical information of the specified substance that exceeds the threshold by comparing the statistical information of the substance specified as the extraction target (content ratio of the extraction target substance) with the threshold. Identify the frame to be played.
  • the frame extraction unit 105 extracts frames that include a substance content rate equal to or greater than a certain threshold value, and generates a frame list based on the extracted frames.
  • step S604 the frame extraction unit 105 sets a range determined by the first frame number and the last frame number in the frame list as one extraction range. That is, the frame extraction unit 105 identifies the first frame number and the last frame number from the frame list generated in step S603, and sets a range between frames determined by the first frame number and the last frame number. Set as one extraction range. Then, the frame extraction unit 105 sets all frames within the extraction range as extraction target frames. In this step, even if the statistical information of the substance (content ratio of the substance to be extracted) is less than the threshold in the extraction range, it is set as the frame to be extracted.
  • step S605 the frame extraction unit 105 acquires a display processing image generated based on the substance identification image.
  • the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
  • step S606 the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame in the extraction range set in step S604, and generates a multi-frame image defined by DICOM as a DICOM image.
  • the frame extraction unit 105 acquires a frame having the same frame number as the frame of the set extraction range from a diagnostic image (virtual monochromatic radiation image), and generates a DICOM image based on the acquired frame.
  • the frame extraction unit 105 if there are a plurality of extraction ranges in the radiographic image, the frame extraction unit 105 generates a plurality of DICOM images for each extraction range.
  • the frame extraction unit 105 Of the radiographic image frames the range defined by the first frame and the last frame where the statistical information of the substance (content rate of the substance to be extracted) is equal to or greater than the threshold is defined as one extraction range, and the frames within the extraction range One DICOM image is generated based on the above.
  • FIG. 7 is a diagram for explaining a frame extraction range determination method in step S604 of FIG.
  • the horizontal axis represents time, and the content rate of the substance to be extracted in each frame is indicated by hatching.
  • the frame extraction unit 105 sets, as one extraction range, a range determined by a first frame in which statistical information is greater than or equal to a threshold and a last frame in which the statistical information is greater than or equal to the threshold.
  • the frame extraction unit 105 extracts a frame corresponding to the extraction range from the frames constituting the display processing image. For example, in the case of the distribution of the statistical information (content ratio of the substance to be extracted) as shown in FIG.
  • the extraction range 703 has the first frame 701 that is equal to or higher than the threshold as the start point and the last frame 702 that is equal to or higher than the threshold as the end point. Is set as one extraction range. That is, the frame number (first frame number) of the first frame 701 in which the statistical information (content ratio of the substance to be extracted) is equal to or greater than the threshold, and the frame number (last frame number) of the last frame 702 that is equal to or greater than the threshold.
  • a range between frames determined by the above is set as one extraction range 703.
  • the frame extraction unit 105 sets all the frames in the extraction range 703 as extraction target frames, and even if the substance statistical information (content ratio of the extraction target substance) is less than the threshold in the extraction range 703, the extraction is performed. Extracted as the target frame.
  • the present embodiment it is possible to extract a frame containing a material of interest in a radiographic image.
  • the material discrimination technology of the energy subtraction method statistical information on the substance specified in advance (content ratio of the extraction target substance) is acquired for each frame, and the statistical information on the substance (of the extraction target in the radiographic image frame) is acquired.
  • frames are extracted based on the condition that the statistical information of the specific substance (content ratio of the substance to be extracted) is equal to or greater than the threshold by using the material discrimination technique of the energy subtraction method.
  • the configuration to be described has been described.
  • a configuration in which information of a plurality of substances included in a radiographic image is displayed on a display unit and a specific substance for extracting a frame is designated will be described.
  • FIG. 8 is a diagram illustrating a functional configuration of the radiation imaging system 100 according to the third embodiment.
  • the configuration of the radiation imaging system 100 including the radiation generation device 11 and the radiation imaging device 10 is the same as that of the first embodiment (FIG. 1).
  • the same functional blocks as those in the radiation imaging apparatus 10 (FIG. 1) are denoted by the same reference numerals.
  • FIG. 9 is a diagram illustrating a configuration of a display unit in which the display control unit 801 according to the third embodiment performs display control.
  • the display control unit 801 displays an image display area 901 for displaying a display processed image (diagnosis image), and a timeline display area 902 for displaying statistical information in each frame in a graph according to the radiographic image capturing time. Display on the screen.
  • a generation notification indicating completion of image generation for a diagnostic image is input from the image generation unit 104 to the display control unit 801
  • a diagnostic image virtual monochromatic radiation image or average energy
  • Display is acquired and displayed in the image display area 901 (FIG. 9) of the display unit.
  • the display control unit 801 acquires, from the frame extraction unit 105, statistical information of each substance (content ratio of the extraction target substance) and information on the extraction range of the frame for each frame, and displays the acquired information on the display unit. Display control is performed in the timeline display area 902 (FIG. 9). Based on the control of the display control unit 801, the timeline display area 902 displays statistical information (content ratio of the substance to be extracted) for each substance frame, and the operator can select the extraction target for frame extraction. It functions as a user interface that can specify substances. In the timeline display area 902, the operator can designate a substance from which a frame is extracted, and the designated statistical information indicating the designated substance is transmitted to the frame extraction unit 105.
  • the timeline display area 902 includes a substance list display unit 903, a statistical information graph display unit 904, a frame extraction range display unit 905, and a reproduction position display unit 906.
  • the frame extraction unit 105 obtains statistical information about a specific substance designated by the display control unit 801 for each frame constituting the substance identification image, and extracts a frame based on the statistical information. For example, the frame extraction unit 105 obtains statistical information (for example, the content rate of each substance) indicating the ratio of the specified specific substance for each frame constituting the substance identification image, and the statistical information is equal to or greater than a certain level.
  • the extracted image is generated by extracting the frame having the ratio of (2) from the frames constituting the display processing image generated based on the substance identification image.
  • the frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
  • the substance list display unit 903 has a substance name list indicating the names of substances and a substance designating part for designating substances to be extracted.
  • the display control unit 801 displays a substance name list of substances acquired from the frame extraction unit 105 on the substance list display unit 903.
  • the substance list display unit 903 displays a check box as a substance designating part for designating a substance to be extracted. When the operator inputs a check box, the input substance is used as a substance to be extracted in the frame. It is specified.
  • the display control unit 801 transmits designated statistical information indicating the designated substance to the frame extracting unit 105.
  • the frame extraction unit 105 acquires a frame extraction range for the substance designated by the substance designation unit, and extracts an extracted image obtained by extracting a frame corresponding to the extraction range from the frames constituting the display processing image (diagnosis image). Generate.
  • the display control unit 801 displays a graph of the statistical information (content rate of the substance to be extracted) of each substance acquired from the frame extraction unit 105 on the statistical information graph display unit 904.
  • the display control unit 801 displays a substance name list indicating the name of the substance and a substance designating part for designating the substance to be extracted side by side with respect to the graph display of the statistical information graph display unit 904.
  • the operator can grasp each substance name and a graph of statistical information (content ratio of a substance to be extracted) in a visual association.
  • the display control unit 801 displays the extraction range of frames in which the statistical information has a certain ratio or more on the graph display of the statistical information graph display unit 904. That is, the display control unit 801 displays the frame extraction range (the frame extraction range display unit 905) acquired from the frame extraction unit 105 on the graph display of the statistical information graph display unit 904.
  • the frame extraction range display unit 905 is indicated by hatching, and such display control allows the operator to visually identify the distribution of the extraction range in the entire frame.
  • the display control unit 801 When the operator presses the playback button 920 in the timeline display area 902, the display control unit 801 performs video playback of the diagnostic image displayed in the image display area 901, and when the operator presses the stop button 930. It is possible to perform display control so as to stop moving image playback.
  • the display control unit 801 displays a reproduction position display unit 906 indicating the reproduction position of the image displayed in the image display area 901 side by side with respect to each statistical information (content rate of substance to be extracted) graph.
  • a reproduction position display unit 906 indicating the reproduction position of the image displayed in the image display area 901 side by side with respect to each statistical information (content rate of substance to be extracted) graph.
  • FIG. 10 is a diagram showing a flow of frame extraction processing of the frame extraction unit 105 in the third embodiment.
  • the frame extraction unit 105 measures how many substances to be extracted are included for each frame from the substance identification image obtained from the substance decomposition unit 103.
  • the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation.
  • the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0.
  • step S1002 the frame extraction unit 105 divides the sum of the pixel values in the frame obtained in step S1001 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. .
  • step S1003 the frame extraction unit 105 determines a substance name list indicating the names of the substances decomposed by the substance decomposition unit 103 by the energy subtraction method, statistical information (content ratio of substances to be extracted) of each substance, and each substance.
  • the frame list of the obtained extraction range is transmitted to the display control unit 801.
  • the frame extraction unit 105 can extract a frame in which the content rate of the substance is included in a certain threshold or more, and can set a series of frames in which the content is equal to or more than the threshold as the extraction range.
  • the frame extraction unit 105 extracts one range determined by the frame number of the first frame in which the statistical information (content ratio of the extraction target substance) is equal to or greater than the threshold and the frame number of the last frame in which the statistical information is equal to or greater than the threshold. It can also be set as a range.
  • the frame extraction unit 105 acquires an extraction range for each substance, and transmits a frame list of frames included in the acquired extraction range to the display control unit 801.
  • the display control unit 801 performs display control in the timeline display area 902 based on the information acquired from the frame extraction unit 105.
  • the operator can designate a substance from which a frame is extracted, and the display control unit 801 transmits designated statistical information indicating the designated substance to the frame extraction unit 105.
  • step S1004 the frame extraction unit 105 identifies the substance corresponding to the specified statistical information received from the display control unit 801 as the extraction target substance.
  • the frame extraction unit 105 acquires a frame list of the extraction range for the specified substance.
  • step S1005 the frame extraction unit 105 acquires a display processing image generated based on the substance identification image.
  • the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
  • step S1006 the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame list of the extraction range acquired in step S1004, and generates a multiframe image defined by DICOM as a DICOM image. .
  • the frame extraction unit 105 acquires a frame having the same frame number as the frame of the set extraction range from a diagnostic image (virtual monochromatic radiation image), and generates a DICOM image based on the acquired frame.
  • the extraction range frame for the substance specified by the operator is diagnosed.
  • the amount of data during storage can be saved.
  • FIG. 11 is a diagram illustrating a configuration example of a timeline display area 1100 in which the display control unit 801 according to the fourth embodiment performs display control.
  • the timeline display area 1100 includes a threshold value changing unit 1101 in addition to the timeline display area 902 of FIG.
  • the threshold value changing unit 1101 displays the setting of the threshold value used in the comparison process with the statistical information (the content rate of the substance to be extracted).
  • the display control unit 801 displays the threshold value used in the comparison process with the statistical information.
  • a threshold value changing unit 1101 for displaying the setting is displayed on the display unit.
  • the display control unit 801 displays the threshold setting display by the threshold changing unit 1101 on the graph display of the statistical information graph display unit 904.
  • the display control unit 801 changes the set threshold based on the change in the display position of the threshold change unit 1101.
  • the display control unit 801 can change the display position of the threshold change unit 1101 up and down based on an operator's change operation via an input unit such as a mouse. By changing the display position of the threshold value changing unit 1101, the set threshold value is changed. When the currently set threshold is changed, the display control unit 801 transmits the changed new threshold to the frame extraction unit 105.
  • the frame extraction unit 105 performs comparison processing with statistical information based on the changed threshold value, and constitutes a display processing image generated based on the substance identification image, in which the statistical information has a ratio of a certain level or more. An extracted image extracted from is generated. Based on the threshold value transmitted from the display control unit 801, the frame extraction unit 105 performs a comparison process between the statistical information (content ratio of the substance to be extracted) and the changed threshold value. The frame extraction unit 105 extracts frames in which the statistical information (content rate of the extraction target substance) is greater than or equal to the changed threshold, and sets a series of frames that are greater than or equal to the threshold as the extraction range.
  • the frame extraction unit 105 determines the range in which the statistical information (content rate of the substance to be extracted) is determined by the frame number of the first frame that is greater than or equal to the changed threshold and the frame number of the last frame that is greater than or equal to the threshold. Can be set as one extraction range.
  • the frame extraction unit 105 acquires an extraction range for each substance, and transmits a list of frames (frame list) included in the acquired extraction range to the display control unit 801.
  • the display control unit 801 changes the display of the extraction range in the timeline display area 902 based on the extraction range frame list transmitted from the frame extraction unit 105.
  • an extraction range 1102 and an extraction range 1103 are extraction ranges that have been changed based on the extraction range frame list transmitted from the frame extraction unit 105.
  • the threshold value can be changed by the operator, and fine adjustment of the frame extraction is possible.
  • the setting of the threshold value can be arbitrarily changed.
  • statistical information content ratio of the substance to be extracted
  • the threshold value are changed.
  • comparison processing can be performed.
  • the extraction range can be changed by comparing the changed threshold value with the statistical information.
  • a frame necessary for diagnosis can be extracted by changing the extraction range.
  • FIG. 12 is a diagram illustrating a configuration example of an image display area 1200 in which the display control unit 801 according to the fifth embodiment performs display control.
  • the image display area 1200 includes an extraction area designation unit 1201 in addition to the image display area 901 of FIG.
  • the extraction area designation unit 1201 designates a pixel range for calculating statistical information (content rate of a substance to be extracted). That is, the extraction area designation unit 1201 designates a pixel range for obtaining the sum of pixel values of the substance identification image when the frame extraction unit 105 calculates statistical information (content ratio of the substance to be extracted).
  • the display control unit 801 causes the display unit to display an extraction area specification unit 1201 that specifies a pixel range for calculating statistical information, and the frame extraction unit 105 sets the pixel value of the image range specified by the extraction area specification unit 1201. Statistical information is acquired based on the information.
  • the display control unit 801 displays the pixel range designated by the extraction area designation unit 1201 on the display processing image (diagnosis image) displayed in the image display area 1200.
  • the display control unit 801 can change the display range of the extraction area designation unit 1201 based on an operator's designation operation via an input unit such as a mouse. By changing and setting the display range of the extraction area specifying unit 1201, the set pixel range is changed.
  • the pixel range set as the initial value has the irradiation field as the pixel range, and if the change setting by the extraction area designation unit 1201 is not performed, the irradiation field that is the initial value setting is maintained as the pixel range. .
  • an additional condition for extracting a frame necessary for diagnosis can be set.
  • the display control unit 801 transmits the changed new pixel range to the frame extraction unit 105.
  • the frame extraction unit 105 calculates statistical information (content ratio of the substance to be extracted) based on the changed pixel range transmitted from the display control unit 801.
  • the frame extraction unit 105 acquires, as statistical information, the result of dividing the sum of the pixel values of the substance identification image within the designated pixel range by the number of pixels in the pixel range from the substance identification image for each frame. First, the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the changed pixel range for each frame. Then, the frame extraction unit 105 divides the sum of the pixel values in the frame by the number of pixels in the pixel range, and calculates statistical information (content ratio of the substance to be extracted) of each substance.
  • the frame extraction unit 105 can set the extraction range of the frame based on the comparison result between the statistical information (content rate of the substance to be extracted) calculated based on the changed pixel range and the threshold value.
  • a series of frames in which statistical information (content ratio of a substance to be extracted) is equal to or greater than a threshold can be set as the extraction range.
  • the statistical information (the content rate of the substance to be extracted) is the frame number of the first frame that is equal to or greater than the threshold value, and the frame number of the last frame that is equal to or greater than the threshold value. It is also possible to set a fixed range as one extraction range.
  • the frame extracting unit 105 includes a substance name list indicating the names of the substances decomposed by the substance decomposing unit 103 by the energy subtraction method, statistical information of each substance calculated based on the changed pixel range (contains the contents of the substance to be extracted)
  • the frame list of the extraction range obtained for each substance is transmitted to the display control unit 801.
  • the display control unit 801 can perform display control of the timeline display area (902 in FIG. 9 and 1100 in FIG. 11) based on the information transmitted from the frame extraction unit 105.
  • the display range of the displayed extraction area designating unit 1201 when calculating statistical information (content ratio of a substance to be extracted) for a region that the operator is paying attention to.
  • the setting of the pixel range to be used can be arbitrarily changed, and a comparison process between the statistical information calculated based on the changed pixel range (content ratio of the substance to be extracted) and the threshold value can be performed. Based on the extraction range obtained from the result of the comparison process, it is possible to extract a frame necessary for the diagnosis with respect to the region focused by the operator. By transmitting an image based on the extracted frame to the PACS 12 as storage data, the amount of data at the time of storage can be saved.
  • the present invention supplies a program that realizes one or more functions of the above-described embodiments to a system or apparatus via a network or a storage medium, and one or more processors in a computer of the system or apparatus read and execute the program This process can be realized. It can also be realized by a circuit (for example, ASIC) that realizes one or more functions.
  • a circuit for example, ASIC

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Abstract

A radiographic device according to the present invention is provided with a generating unit for generating a material discrimination image indicating a distribution for a plurality of materials included in radiographs captured at different radiation energies, and a frame extraction unit for determining statistical information relating to a specific material frames constituting the material discrimination image and extracting a frame on the basis of the statistical information.

Description

放射線撮影装置、放射線撮影システム、放射線撮影方法及びプログラムRadiographic apparatus, radiographic system, radiographic method and program
 本発明は、放射線撮影装置、放射線撮影システム、放射線撮影方法及びプログラムに関する。 The present invention relates to a radiation imaging apparatus, a radiation imaging system, a radiation imaging method, and a program.
 一般に、動画対応の放射線撮影システムでは、保存時のデータ量を節約するために、診断に必要な部分だけを保存することが行われる。特許文献1には、放射線画像において、保存すべきフレーム(例えば、造影剤を用いる検査では、造影剤が映っているフレーム)を、特定位置の画素情報の変化をもとに、自動で抽出する技術が示されている。 Generally, in a radiography system that supports moving images, only the portions necessary for diagnosis are stored in order to save the amount of data at the time of storage. In Patent Document 1, a frame to be stored in a radiographic image (for example, a frame in which a contrast medium is reflected in an examination using a contrast medium) is automatically extracted based on a change in pixel information at a specific position. Technology is shown.
特開平1-209577号公報Japanese Patent Laid-Open No. 1-209577
 しかしながら、特定位置の画素情報の変化を計測する方法では、フレームの特定位置の画素情報に着目したときに、もともと輝度が高いのか、造影剤などの注目する物質が映っているために輝度が高いのか、判別がつかない場合がある。 However, in the method of measuring the change in pixel information at a specific position, when attention is paid to the pixel information at a specific position in the frame, the luminance is high because it is originally high or because a substance of interest such as a contrast medium is reflected. It may not be possible to determine.
 本発明は、注目する物質が含まれているフレームを抽出することが可能な技術を提供する。 The present invention provides a technique capable of extracting a frame containing a target substance.
 本発明の一態様による放射線撮影装置は以下の構成を備える。すなわち、
 放射線撮影装置は、異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成手段と、
 前記物質識別画像を構成する各フレームについて、特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出手段と、を備えることを特徴とする。
A radiation imaging apparatus according to an aspect of the present invention has the following configuration. That is,
The radiographic apparatus includes a generation unit that generates a substance identification image indicating a distribution of a plurality of substances included in a radiographic image captured with different radiation energies,
Extraction means for obtaining statistical information on a specific substance for each frame constituting the substance identification image and extracting a frame based on the statistical information.
 本発明によれば、注目する物質が含まれているフレームを抽出することが可能な技術を提供することが可能になる。 According to the present invention, it is possible to provide a technique capable of extracting a frame containing a target substance.
 本発明のその他の特徴及び利点は、添付図面を参照とした以下の説明により明らかになるであろう。なお、添付図面においては、同じ若しくは同様の構成には、同じ参照番号を付す。 Other features and advantages of the present invention will become apparent from the following description with reference to the accompanying drawings. In the accompanying drawings, the same or similar components are denoted by the same reference numerals.
 添付図面は明細書に含まれ、その一部を構成し、本発明の実施の形態を示し、その記述と共に本発明の原理を説明するために用いられる。
第1実施形態における放射線撮影システムの機能構成を例示する図。 撮影からDICOM画像を生成するまでの処理の流れを示す。 物質の実効原子番号を例示する図。 (各物質の減弱係数(質量減弱係数)と放射線のエネルギー成分との対応関係を例示する図。 第1実施形態におけるフレーム抽出処理の流れを示す図。 第1実施形態におけるフレームの抽出範囲の決定方法を説明する図。 第2実施形態におけるフレーム抽出処理の流れを示す図。 第2実施形態におけるフレームの抽出範囲の決定方法を説明する図。 第3実施形態における放射線撮影システムの機能構成を例示する図。 第3実施形態における表示制御部が表示制御を行う表示部の構成を例示する図。 第3実施形態におけるフレーム抽出処理の流れを示す図。 第4実施形態における表示制御部が表示制御を行うタイムライン表示エリアの構成例を示す図。 第5実施形態における表示制御部が表示制御を行う画像表示エリアの構成例を示す図である。
The accompanying drawings are included in the specification, constitute a part thereof, show an embodiment of the present invention, and are used to explain the principle of the present invention together with the description.
The figure which illustrates the function structure of the radiography system in 1st Embodiment. The flow of processing from shooting to generation of a DICOM image is shown. The figure which illustrates the effective atomic number of a substance. (The figure which illustrates the correspondence of the attenuation coefficient (mass attenuation coefficient) of each substance and the energy component of a radiation. The figure which shows the flow of the frame extraction process in 1st Embodiment. The figure explaining the determination method of the extraction range of the frame in 1st Embodiment. The figure which shows the flow of the frame extraction process in 2nd Embodiment. The figure explaining the determination method of the extraction range of the frame in 2nd Embodiment. The figure which illustrates the functional structure of the radiography system in 3rd Embodiment. The figure which illustrates the structure of the display part which the display control part in 3rd Embodiment controls display. The figure which shows the flow of the frame extraction process in 3rd Embodiment. The figure which shows the structural example of the timeline display area which the display control part in 4th Embodiment performs display control. It is a figure which shows the structural example of the image display area which the display control part in 5th Embodiment performs display control.
 以下、図面を参照して、本発明の実施形態を例示的に詳しく説明する。ただし、この実施形態に記載されている構成要素はあくまで例示であり、以下の個別の実施形態によって限定されるわけではない。尚、放射線には、X線の他、α線、β線、γ線、及び各種粒子線なども含まれる。 Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the drawings. However, the components described in this embodiment are merely examples, and are not limited by the following individual embodiments. The radiation includes α rays, β rays, γ rays, and various particle rays in addition to X-rays.
 以下の実施形態では、放射線発生装置と、放射線撮影装置とを備え、エネルギーサブトラクション画像の生成を行うことが可能な放射線撮影システムについて説明する。以下の各実施形態の放射線撮影システムでは放射線画像の撮影として動画撮影を例として説明する。 In the following embodiment, a radiation imaging system that includes a radiation generation device and a radiation imaging device and can generate an energy subtraction image will be described. In the radiation imaging systems of the following embodiments, moving image capturing will be described as an example of capturing a radiation image.
 [第1実施形態]
 (放射線撮影システム100の構成)
 本実施形態の放射線撮影システム100では、被検体に照射する放射線のエネルギーが異なる複数の放射線画像を処理することによって、新たな画像(例えば、被検体の筋肉などの軟部組織画像や骨などの分布を示す物質識別画像)を得るエネルギーサブトラクション法を用いることが可能である。
[First Embodiment]
(Configuration of radiation imaging system 100)
In the radiographic system 100 according to the present embodiment, a plurality of radiographic images with different radiation energies applied to the subject are processed to obtain new images (for example, soft tissue images such as muscles of the subject, distribution of bones, and the like). It is possible to use an energy subtraction method for obtaining a substance identification image showing
 図1は、第1実施形態における放射線撮影システム100の機能構成を例示する図であり、放射線撮影システムは、放射線発生装置11および放射線撮影装置10を有する。 FIG. 1 is a diagram illustrating a functional configuration of the radiation imaging system 100 according to the first embodiment. The radiation imaging system includes a radiation generator 11 and a radiation imaging apparatus 10.
 エネルギーサブトラクション法による撮影を実施する場合、1枚のサブトラクション画像を生成するために異なる放射線エネルギーで撮影された複数の放射線画像が必要となる。異なる放射線エネルギーで撮影された複数の放射線画像を取得するために、放射線撮影システム100の放射線撮影装置10は、1フレームの撮影期間に複数回のサンプリングを行い、1回の放射線の照射で、高エネルギーの放射線による画像(高エネルギー画像)と低エネルギーの放射線による画像(低エネルギー画像)を生成する。これにより、放射線撮影装置10は、フレーム毎に複数のエネルギー画像、例えば、高エネルギー画像と低エネルギー画像とを1フレーム期間で取得できる。 When imaging by the energy subtraction method is performed, a plurality of radiographic images captured with different radiation energies are required to generate one subtraction image. In order to acquire a plurality of radiation images photographed with different radiation energies, the radiation imaging apparatus 10 of the radiation imaging system 100 performs sampling a plurality of times during one frame imaging period, An image by high energy radiation (high energy image) and an image by low energy radiation (low energy image) are generated. Thereby, the radiation imaging apparatus 10 can acquire a plurality of energy images, for example, a high energy image and a low energy image for each frame in one frame period.
 本実施形態の放射線撮影装置10は、機能構成として、放射線撮影部101、画像取得部102、物質分解部103、画像生成部104、フレーム抽出部105、画像通信部106及び表示制御部107を有する。 The radiation imaging apparatus 10 of the present embodiment includes a radiation imaging unit 101, an image acquisition unit 102, a substance decomposition unit 103, an image generation unit 104, a frame extraction unit 105, an image communication unit 106, and a display control unit 107 as functional configurations. .
 放射線撮影装置10において、放射線撮影部101は、例えば、フラットパネルディテクタ(FPD)を有し、放射線発生装置11から照射された放射線を受けて放射線のエネルギー強度分布情報としての放射線画像の撮影を行う。 In the radiation imaging apparatus 10, the radiation imaging unit 101 includes, for example, a flat panel detector (FPD), and receives radiation irradiated from the radiation generation apparatus 11 and captures a radiation image as radiation energy intensity distribution information. .
 放射線撮影部101は、ユーザインタフェース(UI)を有する表示制御部107から撮影開始指示を受信すると、放射線発生装置11により一定間隔で照射された放射線を受けて、放射線画像を撮影する。 When receiving an imaging start instruction from the display control unit 107 having a user interface (UI), the radiation imaging unit 101 receives radiation irradiated at a predetermined interval by the radiation generation device 11 and captures a radiation image.
 放射線撮影部101は、放射線発生装置11から照射された放射線に基づいて、複数の放射線分布情報を蓄積可能である。例えば、サンプリングホールド信号を制御して、放射線の照射開始から第1のサンプリング時間に蓄積された放射線分布情報(XL)をサンプリングホールドし、第1のサンプリング時間よりも長い第2のサンプリング時間に蓄積された放射線分布情報(XH)をサンプリングホールドする。 The radiation imaging unit 101 can accumulate a plurality of pieces of radiation distribution information based on the radiation emitted from the radiation generator 11. For example, by controlling the sampling hold signal, the radiation distribution information (XL) accumulated during the first sampling time from the start of radiation irradiation is sampled and held, and accumulated during the second sampling time longer than the first sampling time. The received radiation distribution information (XH) is sampled and held.
 すなわち、一回の放射線照射で異なる2つのエネルギー(XL,XH)が蓄積される。エネルギーXLはエネルギーXHよりも低い放射線のエネルギーであり、低エネルギー画像を生成するために使われ、エネルギーXHは高エネルギー画像を生成するため使われる。1フレームの撮影期間に複数回のサンプリングを行うことで、フレーム毎に複数のエネルギー画像、例えば、高エネルギー画像と低エネルギー画像とを取得できる。 That is, two different energies (XL, XH) are accumulated by one irradiation. The energy XL is radiation energy lower than the energy XH and is used to generate a low energy image, and the energy XH is used to generate a high energy image. A plurality of energy images, for example, a high energy image and a low energy image can be acquired for each frame by performing sampling a plurality of times during one frame shooting period.
 放射線撮影部101は、放射線動画(放射線画像)の1フレームを生成するために、フレーム毎に複数のエネルギー画像として、例えば、高エネルギー画像と低エネルギー画像を撮影し、撮影した放射線画像(低エネルギー画像、高エネルギー画像)を画像取得部102に出力する。 In order to generate one frame of a radiation moving image (radiation image), the radiation imaging unit 101 captures, for example, a high energy image and a low energy image as a plurality of energy images for each frame, and the captured radiation image (low energy) Image, high energy image) is output to the image acquisition unit 102.
 画像取得部102は、放射線撮影部101で生成された放射線画像を画像毎に取得する。例えば、2つの異なる放射線エネルギーで放射線撮影を行っている場合は、1フレーム生成用に、高エネルギー画像と低エネルギー画像とを取得し、取得した画像(高エネルギー画像及び低エネルギー画像)を物質分解部103に出力する。 The image acquisition unit 102 acquires the radiation image generated by the radiation imaging unit 101 for each image. For example, when radiography is performed with two different radiation energies, a high energy image and a low energy image are acquired for generating one frame, and the acquired images (a high energy image and a low energy image) are subjected to material decomposition. Output to the unit 103.
 放射線の各エネルギーレベルに対応する各物質の減弱係数は既知であるため、既知の減弱係数を用いて、物質分解部103は、エネルギーサブトラクション法により、高エネルギー画像21と低エネルギー画像22から2つの方程式を立て、解を求めることによって、実効原子番号と面密度を求めることが出来る。ここで、実効原子番号とは、元素、化合物、混合物の構成元素を平均的に見た場合に相当する原子番号を示し、その物質と同じ割合で光子の減弱をする仮想の元素の原子番号を示す定量指標である。 Since the attenuation coefficient of each substance corresponding to each energy level of radiation is known, using the known attenuation coefficient, the substance decomposing unit 103 uses the energy subtraction method to extract two from the high energy image 21 and the low energy image 22. The effective atomic number and areal density can be obtained by establishing an equation and finding the solution. Here, the effective atomic number indicates the atomic number corresponding to the average of the constituent elements of an element, compound, or mixture, and the atomic number of a hypothetical element that attenuates photons at the same rate as that substance. It is the quantitative index shown.
 図3Aは、物質分解部103での物質識別画像の生成に利用される物質の実効原子番号(データテーブル)を例示する図である。また、図3Bは、各物質の減弱係数(質量減弱係数)と放射線のエネルギー成分(単一波長)との対応関係(データ線図)を例示する図である。図3A、図3Bの対応関係(データテーブル、データ線図)を示す情報を、放射線撮影装置10の記憶部109(内部メモリ)に事前に保存しておき、エネルギーサブトラクション法の物質弁別処理を実行する際に、図3Aのデータテーブルを参照することで、物質を弁別することができる。 FIG. 3A is a diagram illustrating an effective atomic number (data table) of a substance used for generating a substance identification image in the substance decomposing unit 103. FIG. 3B is a diagram illustrating the correspondence (data diagram) between the attenuation coefficient (mass attenuation coefficient) of each substance and the energy component (single wavelength) of radiation. Information indicating the correspondence relationship (data table, data diagram) of FIGS. 3A and 3B is stored in advance in the storage unit 109 (internal memory) of the radiation imaging apparatus 10, and the material discrimination process of the energy subtraction method is executed. In doing so, the substance can be discriminated by referring to the data table of FIG. 3A.
 物質分解部103(生成部)は、異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する。物質分解部103は、エネルギーサブトラクション法の物質弁別処理により取得した実効原子番号と面密度から、実効原子番号に対応した特定物質の分布を示す物質識別画像を生成し、生成した物質識別画像を画像生成部104及びフレーム抽出部105に出力する。尚、物質識別画像は、物質の実効原子番号又は面密度に基づいて生成されてもよい。 The substance decomposing unit 103 (generating unit) generates a substance identification image indicating distributions of a plurality of substances included in radiographic images taken with different radiation energies. The substance decomposition unit 103 generates a substance identification image indicating the distribution of the specific substance corresponding to the effective atomic number from the effective atomic number and the surface density acquired by the substance discrimination process of the energy subtraction method, and the generated substance identification image is displayed as an image. The data is output to the generation unit 104 and the frame extraction unit 105. The substance identification image may be generated based on the effective atomic number or the surface density of the substance.
 画像生成部104は、物質識別画像に基づいて、診断用の画像を生成する。すなわち、画像生成部104は、複数の物質のそれぞれについて生成した物質識別画像に基づいて、表示処理画像(診断用の画像)を生成する。画像生成部104は、放射線の一つのエネルギー成分に基づいて、複数の物質のうち特定の物質を強調する画像を表示処理画像(診断用の画像)として生成する。ここで、表示処理画像には、以下に説明する仮想単色放射線画像が含まれる。放射線発生装置11から照射される放射線は、複数のエネルギー成分を含んでいるが、画像生成部104は、複数のエネルギー成分のうち、いずれか一つのエネルギー成分に基づく放射線画像(仮想単色放射線画像)を、物質識別画像に基づいて生成する。 The image generation unit 104 generates a diagnostic image based on the substance identification image. That is, the image generation unit 104 generates a display processing image (diagnosis image) based on the substance identification image generated for each of the plurality of substances. The image generation unit 104 generates, as a display processing image (diagnostic image), an image that emphasizes a specific substance among a plurality of substances based on one energy component of radiation. Here, the display processing image includes a virtual monochromatic radiation image described below. Although the radiation irradiated from the radiation generator 11 includes a plurality of energy components, the image generation unit 104 includes a radiation image (virtual monochromatic radiation image) based on any one of the plurality of energy components. Is generated based on the substance identification image.
 放射線のエネルギー成分(単一波長)が選択された場合、選択されたエネルギー成分(単一波長)に対応する各物質の減弱係数を図3Bのデータ線図から取得することができる。放射線の各エネルギー成分に対応する物質の減弱係数は既知であるため(図3B)、既知の減弱係数と、取得された物質識別画像とを組み合せることで、任意のエネルギー成分における画素値の分布が求められる。画像生成部104は、任意のエネルギー成分における画素値の分布を示す画像を、仮想の単色放射線で照射した場合の仮想単色放射線画像として生成することができる。 When the energy component (single wavelength) of radiation is selected, the attenuation coefficient of each substance corresponding to the selected energy component (single wavelength) can be obtained from the data diagram of FIG. 3B. Since the attenuation coefficient of the substance corresponding to each energy component of radiation is known (FIG. 3B), the pixel value distribution in an arbitrary energy component can be obtained by combining the known attenuation coefficient and the acquired substance identification image. Is required. The image generation part 104 can generate | occur | produce the image which shows distribution of the pixel value in arbitrary energy components as a virtual monochromatic radiation image at the time of irradiating with a virtual monochromatic radiation.
 仮想単色放射線画像を生成する際のエネルギー成分は任意に選択可能であるが、例えば、画像生成部104は、操作者により設定されたエネルギー成分に対応する減弱係数と物質識別画像とを組み合せることで、設定されたエネルギー成分における画素値の分布を取得して、診断用の画像(仮想単色放射線画像)として生成することが可能である。 The energy component for generating the virtual monochromatic radiation image can be arbitrarily selected. For example, the image generation unit 104 combines the attenuation coefficient corresponding to the energy component set by the operator and the substance identification image. Thus, it is possible to acquire the distribution of pixel values in the set energy component and generate it as a diagnostic image (virtual monochromatic radiation image).
 操作者は検査・診断の目的に応じて特定のエネルギー成分の画像を見慣れているため、操作者が設定したエネルギー成分に対応した診断用の画像(仮想単色放射線画像)を生成することで、より操作者に対して見やすい画像表示を提供することが可能になる。 Since the operator is familiar with the image of a specific energy component according to the purpose of the inspection / diagnosis, it is possible to generate a diagnostic image (virtual monochromatic radiation image) corresponding to the energy component set by the operator. It is possible to provide an easy-to-view image display for the operator.
 放射線吸収率がピークを示す放射線のエネルギー成分は物質毎に異なるため、特定物質の放射線吸収率が最大となるエネルギー成分の単色放射線画像を作成することで弁別された特定物質が強調された診断用の画像を生成することができる。図3Bのデータ線図に基づいて、特定の物質を強調するようなエネルギー成分に対応する減弱係数を取得し、取得した減弱係数と物質識別画像とを組み合せることで、特定の物質を強調するエネルギー成分における画素値の分布を取得して、診断用の画像(仮想単色放射線画像)として生成することができる。 Since the energy component of the radiation that shows a peak in the radiation absorption rate differs from material to material, the diagnostic material emphasizes the specific material identified by creating a monochromatic radiation image of the energy component that maximizes the radiation absorption rate of the specific material. Images can be generated. Based on the data diagram of FIG. 3B, an attenuation coefficient corresponding to an energy component that emphasizes the specific substance is acquired, and the specific substance is emphasized by combining the acquired attenuation coefficient and the substance identification image. The distribution of pixel values in the energy component can be acquired and generated as a diagnostic image (virtual monochromatic radiation image).
 放射線撮影装置10の記憶部109(内部メモリ)において、図3A、図3Bの対応関係(データテーブル、データ線図)を示す情報を記憶しておき、物質弁別処理においてデータテーブル(図3A)を参照することで各物質の弁別ができ、データ線図(図3Bを参照することで、任意のエネルギー成分に対応する仮想単色放射線画像を生成することが可能である。 In the storage unit 109 (internal memory) of the radiation imaging apparatus 10, information indicating the correspondence (data table, data diagram) of FIGS. 3A and 3B is stored, and the data table (FIG. 3A) is stored in the substance discrimination processing. Each substance can be discriminated by referring to it, and a virtual monochromatic radiation image corresponding to an arbitrary energy component can be generated by referring to a data diagram (see FIG. 3B).
 尚、物質分解部103及び画像生成部104は、データテーブル、データ線図の対応関係を、画像通信部106を介した外部機器との通信により取得して、物質の弁別及び仮想単色放射線画像を生成することも可能である。 Note that the substance decomposition unit 103 and the image generation unit 104 acquire the correspondence relationship between the data table and the data diagram through communication with an external device via the image communication unit 106, and identify the substance discrimination and virtual monochromatic radiation image. It is also possible to generate.
 診断用の画像は仮想単色放射線画像に限られず、画像生成部104は、診断用の画像として、前述した高エネルギー画像と低エネルギー画像の画素値を平均化した画像(平均エネルギー画像)を生成することも可能である。 The diagnostic image is not limited to the virtual monochromatic radiation image, and the image generation unit 104 generates an image (average energy image) obtained by averaging the pixel values of the high energy image and the low energy image described above as the diagnostic image. It is also possible.
 画像生成部104は、生成した診断用の画像(仮想単色放射線画像または平均エネルギー画像)を表示制御部107に出力する。 The image generation unit 104 outputs the generated diagnostic image (virtual monochromatic radiation image or average energy image) to the display control unit 107.
 フレーム抽出部105(抽出部)は、物質識別画像を構成する各フレームについて、特定の物質に関する統計情報を求め、統計情報に基づいてフレームを抽出する。例えば、フレーム抽出部105は、物質識別画像を構成する各フレームについて、特定の物質が含まれる割合を示す統計情報(例えば、各物質の含有率など)を求め、統計情報が一定以上の割合となるフレームを、物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像を生成する。フレーム抽出部105は、表示処理画像を構成するフレームから、統計情報が一定以上の割合となるフレームに対応するフレームを抽出して抽出画像を生成する。 The frame extraction unit 105 (extraction unit) obtains statistical information about a specific substance for each frame constituting the substance identification image, and extracts a frame based on the statistical information. For example, the frame extraction unit 105 obtains statistical information (for example, the content rate of each substance) indicating the ratio of a specific substance for each frame constituting the substance identification image, The extracted image is generated by extracting the frame to be obtained from the frame constituting the display processing image generated based on the substance identification image. The frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
 尚、統計情報については、物質識別画像に基づいて、各物質の含有率を取得する他、エネルギーサブトラクション法の物質弁別処理により得られた実効原子番号の分布を示す画像を用いることも可能である。例えば、各フレームにおいて、実効原子番号で特定される物質がフレームを占める割合(含有率)を求めてもよい。 For statistical information, in addition to acquiring the content of each substance based on the substance identification image, it is also possible to use an image showing the distribution of effective atomic numbers obtained by substance discrimination processing of the energy subtraction method. . For example, in each frame, the ratio (content ratio) that the substance specified by the effective atomic number occupies the frame may be obtained.
 フレーム抽出部105は、物質識別画像に基づいて、フレーム抽出に用いる統計情報を取得し、取得した統計情報に基づいて、診断用の画像(仮想単色放射線画像または平均エネルギー画像)からフレームを抽出する。フレーム抽出部105は、物質分解部103から取得した物質識別画像から、例えば、輝度や濃度を示す画素値の情報を統計情報として取得し、統計情報と閾値との比較により、指定された物質の統計情報が閾値以上含まれるフレームを特定する。 The frame extraction unit 105 acquires statistical information used for frame extraction based on the substance identification image, and extracts a frame from the diagnostic image (virtual monochromatic radiation image or average energy image) based on the acquired statistical information. . The frame extraction unit 105 acquires, for example, pixel value information indicating luminance and density from the substance identification image acquired from the substance decomposition unit 103 as statistical information, and compares the statistical information with a threshold value to determine the specified substance. A frame including statistical information equal to or greater than a threshold is specified.
 また、フレーム抽出部105は、物質識別画像に基づいて特定したフレームと同じフレーム番号のフレームを、画像生成部104から取得した診断用の画像(仮想単色放射線画像、または、平均エネルギー画像)からを抽出し、DICOM(Digital Imaging and COmmunications in Medicine)で規定されているマルチフレーム画像をDICOM画像として生成する。フレーム抽出部105は、統計情報が一定以上の割合となるフレームを、物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像に基づいて、DICOM規格に基づいたDICOM画像(保存画像)を生成する。フレーム抽出部105は、表示処理画像を構成するフレームから、統計情報が一定以上の割合となるフレームに対応するフレームを抽出して抽出画像を生成する。 Further, the frame extraction unit 105 extracts a frame having the same frame number as the frame specified based on the substance identification image from the diagnostic image (virtual monochromatic radiation image or average energy image) acquired from the image generation unit 104. Extract and generate a multi-frame image defined by DICOM (Digital Imaging and COmmunications in Medicine) as a DICOM image. The frame extraction unit 105 uses a DICOM image (based on the DICOM standard) based on an extracted image extracted from a frame that constitutes a display processing image generated based on the substance identification image. Saved image). The frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
 画像通信部106は、ネットワークを介して外部機器と通信可能に構成されており、フレーム抽出部105で抽出されたフレームの情報や、生成されたDICOM画像をPACS(Picture Archive and Communication System)12に送信する。検査終了など、表示制御部107からの操作者の指示が画像通信部106に入力されると、画像通信部106は、フレーム抽出部105からフレーム抽出されたDICOM画像を取得し、DICOM規格に準拠したプロトコルでPACS12に送信する。画像通信部106は、例えば、被検体の情報や撮影条件等の情報を、DICOM画像の付帯情報としてPACS12に送信することも可能である。 The image communication unit 106 is configured to be able to communicate with an external device via a network. The frame information extracted by the frame extraction unit 105 and the generated DICOM image are transferred to a PACS (Picture Archive Communication System) 12. Send. When an operator's instruction from the display control unit 107 is input to the image communication unit 106 such as the end of inspection, the image communication unit 106 acquires the DICOM image extracted from the frame extraction unit 105 and conforms to the DICOM standard. Is transmitted to the PACS 12 using the protocol described above. For example, the image communication unit 106 can also transmit information about the subject, imaging conditions, and the like to the PACS 12 as supplementary information of the DICOM image.
 PACS12は、画像通信部106からDICOM画像ファイルを受信して保存し、DICOM画像を診断用に表示することが可能である。放射線画像において注目する特定の物質が含まれているフレームを抽出した画像を保存用のデータとしてPACS12に送信することで、保存時のデータ量を節約するとともに、特定位置の画素情報(例えば、輝度や濃度などの画素値)の変化の計測結果によらず、放射線画像において注目する物質が閾値以上含まれているフレームを、精度よく抽出することが可能になる。 The PACS 12 can receive and store the DICOM image file from the image communication unit 106 and display the DICOM image for diagnosis. By transmitting an image obtained by extracting a frame containing a specific substance of interest in a radiographic image to the PACS 12 as storage data, the data amount at the time of storage is saved, and pixel information (for example, luminance) at a specific position is saved. It is possible to accurately extract a frame in which a substance of interest in a radiographic image is included in a radiation image at a threshold value or more, regardless of the measurement result of the change in the pixel value such as the density and the pixel value.
 表示制御部107は、放射線画像を表示部に表示するための表示制御を行う。表示制御部107は画像生成部104から、診断用の画像について画像生成の完了を示す生成通知が入力されると、表示制御部107は、画像生成部104から診断用の画像(仮想単色放射線画像、または、平均エネルギー画像)を取得し、表示部に表示する。尚、表示部は、放射線撮影装置10の構成として設けてもよく、放射線撮影装置10の外部構成としてもよい。 The display control unit 107 performs display control for displaying a radiation image on the display unit. When the display control unit 107 receives a generation notification indicating completion of image generation for the diagnostic image from the image generation unit 104, the display control unit 107 displays the diagnostic image (virtual monochromatic radiation image) from the image generation unit 104. Or an average energy image) is acquired and displayed on the display unit. The display unit may be provided as a configuration of the radiation imaging apparatus 10 or may be an external configuration of the radiation imaging apparatus 10.
 (処理シーケンス)
 図2は、第1実施形態における放射線画像の撮影からDICOM規格に対応した画像(DICOM画像)を生成するまでの処理の流れを示すシーケンス図である。このシーケンス図では、放射線撮影部101で撮影された複数の異なるエネルギー画像が複数の物質識別画像に分解され、診断用の画像(この例では、仮想単色放射線画像)が生成され、PACS12へ出力するためのDICOM画像が生成されるまでの処理の流れを示している。
(Processing sequence)
FIG. 2 is a sequence diagram showing a flow of processing from the radiographic image capturing to the generation of an image (DICOM image) corresponding to the DICOM standard in the first embodiment. In this sequence diagram, a plurality of different energy images captured by the radiation imaging unit 101 are decomposed into a plurality of substance identification images, and a diagnostic image (in this example, a virtual monochromatic radiation image) is generated and output to the PACS 12. The flow of a process until the DICOM image for this is produced | generated is shown.
 ステップS201において、放射線撮影部101は、放射線画像の1フレームを生成するために、フレーム毎に複数のエネルギー画像として、高エネルギー画像21と低エネルギー画像22を撮影し、撮影した高エネルギー画像21及び低エネルギー画像22を画像取得部102に出力する。 In step S201, the radiation imaging unit 101 captures the high energy image 21 and the low energy image 22 as a plurality of energy images for each frame in order to generate one frame of the radiation image, and the captured high energy image 21 and The low energy image 22 is output to the image acquisition unit 102.
 ステップS202において、画像取得部102は、放射線撮影部101で撮影された高エネルギー画像21及び低エネルギー画像22を取得して、物質分解部103に取得した複数のエネルギー画像を出力する。 In step S <b> 202, the image acquisition unit 102 acquires the high energy image 21 and the low energy image 22 captured by the radiation imaging unit 101, and outputs the acquired plurality of energy images to the substance decomposition unit 103.
 ステップS203において、物質分解部103は、エネルギーサブトラクション法により、高エネルギー画像21と低エネルギー画像22から物質識別画像の生成を行う。例えば、物質分解部103は、水、骨、脂肪など人体を構成する各物質についての物質識別画像(各物質についての物質識別画像を総称して、以下「人体密度画像23」という)や、血管に注入された造影剤についての物質識別画像(例えば、造影剤密度画像24)を生成する。人体密度画像23と造影剤密度画像24は、表示処理2001とフレーム抽出処理2002で利用される。 In step S203, the substance decomposition unit 103 generates a substance identification image from the high energy image 21 and the low energy image 22 by the energy subtraction method. For example, the substance decomposing unit 103 includes a substance identification image for each substance constituting the human body such as water, bone, and fat (hereinafter, the substance identification image for each substance is collectively referred to as “human body density image 23”), blood vessel A substance identification image (for example, a contrast medium density image 24) is generated for the contrast medium injected into. The human body density image 23 and the contrast medium density image 24 are used in the display process 2001 and the frame extraction process 2002.
 図2において、表示処理2001は、物質識別画像に基づいて、診断用の画像を生成し、生成した画像を表示する処理である。また、フレーム抽出処理2002は、物質識別画像に基づいて、特定物質が含まれるフレームを抽出し、抽出したフレームに基づいてDICOM画像を生成する処理である。 In FIG. 2, display processing 2001 is processing for generating a diagnostic image based on the substance identification image and displaying the generated image. The frame extraction process 2002 is a process for extracting a frame including a specific substance based on the substance identification image and generating a DICOM image based on the extracted frame.
 (表示処理2001)
 まず、表示処理2001のステップS204において、物質分解部103は、生成した人体密度画像23と造影剤密度画像24を画像生成部104に出力する。
(Display process 2001)
First, in step S <b> 204 of the display process 2001, the substance decomposition unit 103 outputs the generated human body density image 23 and the contrast agent density image 24 to the image generation unit 104.
 次に、ステップS205において、画像生成部104は、診断用の画像として、仮想単色放射線画像25を生成する。高エネルギー画像21と低エネルギー画像22が、物質識別画像である人体密度画像23と造影剤密度画像24に弁別されれば、人体を構成する各物質や造影剤の実効原子番号や減弱係数は既知であるので、減弱係数に対応する放射線のエネルギー成分(単一波長)について、仮想単色放射線画像25を生成できる。 Next, in step S205, the image generation unit 104 generates a virtual monochromatic radiation image 25 as a diagnostic image. If the high energy image 21 and the low energy image 22 are discriminated into a human body density image 23 and a contrast medium density image 24 which are substance identification images, the effective atomic number and attenuation coefficient of each substance and contrast medium constituting the human body are known. Therefore, the virtual monochromatic radiation image 25 can be generated for the radiation energy component (single wavelength) corresponding to the attenuation coefficient.
 次に、ステップS206において、画像生成部104が表示制御部107に画像の生成通知を行う。画像生成部104は、診断用の画像の生成処理が完了すると画像生成の完了を示す生成通知を表示制御部107に出力する。 In step S206, the image generation unit 104 notifies the display control unit 107 of image generation. When the generation processing of the diagnostic image is completed, the image generation unit 104 outputs a generation notification indicating the completion of image generation to the display control unit 107.
 次に、ステップS207では、表示制御部107が画像生成部104から仮想単色放射線画像25を取得し、表示する。本ステップでは、画像生成部104から、診断用の画像について画像生成の完了を示す生成通知が入力されると、表示制御部107は、画像生成部104から診断用の画像(仮想単色放射線画像、または、平均エネルギー画像)を取得し、表示部に表示する。 Next, in step S207, the display control unit 107 acquires the virtual monochromatic radiation image 25 from the image generation unit 104 and displays it. In this step, when a generation notification indicating completion of image generation for a diagnostic image is input from the image generation unit 104, the display control unit 107 displays a diagnostic image (virtual monochromatic radiation image, Alternatively, an average energy image) is acquired and displayed on the display unit.
 (フレーム抽出処理2002)
 まず、フレーム抽出処理2002のステップS208において、物質分解部103は、生成した物質識別画像(例えば、人体密度画像23と造影剤密度画像24)をフレーム抽出部105に送信する。
(Frame extraction process 2002)
First, in step S208 of the frame extraction process 2002, the substance decomposing unit 103 transmits the generated substance identification image (for example, the human body density image 23 and the contrast agent density image 24) to the frame extracting unit 105.
 次に、ステップS209において、フレーム抽出部105はフレーム抽出処理を実行する。本ステップでは、フレーム抽出部105は、物質識別画像に基づいて、フレーム抽出に用いる統計情報を取得し、取得した統計情報に基づいて、フレームを抽出する。フレーム抽出部105は、物質識別画像から取得した統計情報と閾値との比較により、指定された物質の統計情報が閾値以上含まれるフレームを特定する。 Next, in step S209, the frame extraction unit 105 executes a frame extraction process. In this step, the frame extraction unit 105 acquires statistical information used for frame extraction based on the substance identification image, and extracts a frame based on the acquired statistical information. The frame extraction unit 105 identifies a frame in which the statistical information of the designated substance is included in the threshold value or more by comparing the statistical information acquired from the substance identification image with the threshold value.
 次に、ステップS210において、フレーム抽出部105は、画像生成部104から仮想単色放射線画像25を取得し、DICOM画像を作成する。フレーム抽出部105は、物質識別画像に基づいて特定したフレームと同じフレーム番号のフレームを、画像生成部104から取得した診断用の画像(例えば、仮想単色放射線画像)から取得し、DICOMで規定されているマルチフレーム画像をDICOM画像として生成する。 Next, in step S210, the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 from the image generation unit 104 and creates a DICOM image. The frame extraction unit 105 acquires a frame having the same frame number as the frame identified based on the substance identification image from a diagnostic image (for example, a virtual monochromatic radiation image) acquired from the image generation unit 104, and is defined by DICOM. The generated multi-frame image is generated as a DICOM image.
 図4は、第1実施形態におけるフレーム抽出部105のフレーム抽出処理2002の流れを示す図である。 FIG. 4 is a diagram showing a flow of the frame extraction process 2002 of the frame extraction unit 105 in the first embodiment.
 物質分解部103は、生成した物質識別画像(人体密度画像23と造影剤密度画像24)をフレーム抽出部105に送信し、フレーム抽出部105は以下の処理の流れによりフレーム抽出処理を実行する。 The substance decomposition unit 103 transmits the generated substance identification image (the human body density image 23 and the contrast medium density image 24) to the frame extraction unit 105, and the frame extraction unit 105 performs a frame extraction process according to the following processing flow.
 まず、ステップS401において、フレーム抽出部105は、物質分解部103から得られた物質識別画像から、フレームごとに、抽出対象の物質がどれくらい含まれるかを計測する。具体的には、フレーム抽出部105は、放射線が照射された照射野内の物質識別画像の画素値の合計を計算する。ここで、画素値は0.0から1.0の値であり、その物質がフレームに含まれていなければ画素値は0.0であり、物質がフレームに含まれていれば、画素値は0.0より大きく、1.0以下の値となる。そして、フレームにおける画素値の合計値も、その物質が多く含まれているほど大きくなる。すなわち、物質識別画像のフレームの画素値は、その物質がフレームに多く含まれているほど大きくなる。 First, in step S401, the frame extraction unit 105 measures how much substance to be extracted is included for each frame from the substance identification image obtained from the substance decomposition unit 103. Specifically, the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation. Here, the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0. The total pixel value in the frame also increases as the amount of the substance is increased. That is, the pixel value of the frame of the substance identification image increases as the substance is included in the frame.
 ステップS402において、フレーム抽出部105は、物質識別画像から、フレームごとに、放射線が照射された照射野内の物質識別画像の画素値の合計を、照射野の画素数で除算した結果を統計情報として取得する。フレーム抽出部105は、ステップS401で得られた、フレームにおける画素値の合計を照射野の画素数で除算し、各物質の統計情報(抽出対象の物質の含有率)を計算する。画素数を合計した値をそのまま扱わず、照射野の画素数で除算した含有率を算出することで、放射線撮影部101の解像度が異なる場合にも対応することが可能になる。 In step S402, the frame extraction unit 105 obtains, as statistical information, the result of dividing the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation from the substance identification image by the number of pixels of the irradiation field for each frame. get. The frame extraction unit 105 divides the total pixel value in the frame obtained in step S401 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. By calculating the content ratio divided by the number of pixels in the irradiation field without directly handling the total number of pixels, it is possible to cope with cases where the resolution of the radiation imaging unit 101 is different.
 次に、ステップS403において、フレーム抽出部105は、抽出対象として指定された物質、例えば、造影剤などの統計情報と閾値との比較により、指定された物質の統計情報が閾値以上含まれるフレームを特定する。フレーム抽出部105は、物質の含有率が一定の閾値以上含まれるフレームを抽出し、一定の閾値以上含まれる一連のフレームにより定まる範囲をフレームの抽出範囲として設定する。フレーム抽出部105は、抽出範囲に含まれるフレームに基づいて、抽出範囲のフレームリストを生成する。 Next, in step S403, the frame extraction unit 105 compares a specified substance, for example, statistical information such as a contrast agent, with a threshold value, and includes a frame that includes the statistical information of the specified substance at a threshold value or more. Identify. The frame extraction unit 105 extracts a frame in which the content rate of the substance is included in a certain threshold or more, and sets a range determined by a series of frames included in the certain threshold or more as a frame extraction range. The frame extraction unit 105 generates a frame list of the extraction range based on the frames included in the extraction range.
 ステップS404において、フレーム抽出部105は、物質識別画像に基づいて生成した表示処理画像を取得する。例えば、フレーム抽出部105は、表示処理画像として、画像生成部104で生成された仮想単色放射線画像25を取得する。 In step S404, the frame extraction unit 105 acquires a display processing image generated based on the substance identification image. For example, the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
 次に、ステップS405において、フレーム抽出部105は、ステップS403で生成した抽出範囲のフレームリストに対応する仮想単色放射線画像のフレームを抽出し、抽出範囲毎にDICOMで規定されているマルチフレーム画像をDICOM画像として生成する。抽出範囲のフレームリストには、フレームを特定するフレーム情報として、放射線画像におけるフレーム番号の情報が含まれており、フレーム抽出部105は、物質識別画像に基づいて特定したフレームと同じフレーム番号のフレームを、診断用の画像(仮想単色放射線画像)から取得し、取得したフレームに基づいてDICOM画像を生成する。例えば、放射線画像において、抽出範囲の数が複数であれば、フレーム抽出部105は、各抽出範囲について複数のDICOM画像を生成する。 Next, in step S405, the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame list of the extraction range generated in step S403, and creates a multi-frame image defined by DICOM for each extraction range. Generated as a DICOM image. The frame list of the extraction range includes frame number information in the radiographic image as frame information for specifying the frame, and the frame extraction unit 105 has the same frame number as the frame specified based on the substance identification image. Is acquired from a diagnostic image (virtual monochromatic radiation image), and a DICOM image is generated based on the acquired frame. For example, if there are a plurality of extraction ranges in the radiographic image, the frame extraction unit 105 generates a plurality of DICOM images for each extraction range.
 そして、フレーム抽出部105は、放射線画像と、放射線画像に対する物質ごとの抽出範囲を示すインデックス情報とを、組み合せて記憶部109に記憶する。このインデックス情報を参照することにより、放射線画像において、物質ごとにフレームを抽出する範囲を検索し、記憶部109に記憶されている放射線画像に基づいて診断用の画像を再度生成することが可能になる。 Then, the frame extraction unit 105 stores the radiation image and index information indicating the extraction range for each substance with respect to the radiation image in the storage unit 109 in combination. By referring to this index information, it is possible to search a range in which a frame is extracted for each substance in a radiographic image and regenerate a diagnostic image based on the radiographic image stored in the storage unit 109. Become.
 図5は、図4のステップS403における、フレームの抽出範囲の決定方法を説明する図である。図5において、横軸は時間であり、各フレームにおける抽出対象の物質の含有率をハッチングで示している。例えば、フレーム501は、抽出対象の物質の含有率が閾値以上であることを示している。 FIG. 5 is a diagram for explaining a frame extraction range determination method in step S403 in FIG. In FIG. 5, the horizontal axis represents time, and the content rate of the substance to be extracted in each frame is indicated by hatching. For example, the frame 501 indicates that the content rate of the substance to be extracted is equal to or greater than a threshold value.
 フレーム抽出部105は、物質識別画像を構成するフレームから、統計情報が一定の閾値以上含まれるフレームを抽出し、閾値以上となる一連のフレームを抽出範囲として設定する。そして、フレーム抽出部105は、抽出範囲に対応するフレームを、表示処理画像を構成するフレームから抽出する。まず、フレーム抽出部105は、物質の統計情報(抽出対象の物質の含有率)が閾値以上含まれるフレームを特定する。フレーム抽出部105は、物質の含有率が一定の閾値以上含まれるフレームを抽出し、閾値以上となる一連のフレームを抽出範囲とする。図5のような含有率の分布である場合、抽出範囲502と抽出範囲503が抽出され、フレーム抽出部105は、抽出範囲に含まれるフレームに基づいて、抽出範囲のフレームリストを生成し、保持する。閾値を超えていないフレームは抽出されない。 The frame extraction unit 105 extracts a frame including statistical information that is greater than or equal to a certain threshold value from the frames constituting the substance identification image, and sets a series of frames that are equal to or greater than the threshold value as an extraction range. Then, the frame extraction unit 105 extracts a frame corresponding to the extraction range from the frames constituting the display processing image. First, the frame extraction unit 105 identifies a frame in which the statistical information of the substance (the content rate of the substance to be extracted) is included more than a threshold. The frame extraction unit 105 extracts a frame in which the content rate of the substance is equal to or greater than a certain threshold, and sets a series of frames that are equal to or greater than the threshold as an extraction range. In the case of the distribution of the content rate as shown in FIG. 5, the extraction range 502 and the extraction range 503 are extracted, and the frame extraction unit 105 generates and holds a frame list of the extraction range based on the frames included in the extraction range. To do. Frames that do not exceed the threshold are not extracted.
 本実施形態によれば、放射線画像において注目する物質が含まれているフレームを抽出することができる。エネルギーサブトラクション法の物質弁別技術を利用し、事前に指定した物質の統計情報(抽出対象の物質の含有率)をフレームごとに取得し、閾値以上のフレームを診断に必要なフレームとして抽出し、抽出したフレームに基づく画像を保存用のデータとしてPACSに送信することで、保存時のデータ量を節約するとともに、特定位置の画素情報(例えば、輝度や濃度などの画素値)の変化の計測結果によらず、放射線画像において注目する物質が閾値以上含まれているフレームを、精度よく抽出することが可能になる。 According to the present embodiment, it is possible to extract a frame containing a material of interest in a radiographic image. Using material discrimination technology of the energy subtraction method, statistical information (content ratio of the extraction target substance) of the specified substance is acquired for each frame, and frames above the threshold are extracted and extracted as frames necessary for diagnosis. By sending an image based on the frame to the PACS as data for storage, the data amount at the time of storage is saved, and the measurement result of changes in pixel information (for example, pixel values such as luminance and density) at a specific position is saved. Regardless, it is possible to accurately extract a frame in which a target substance is included in the radiographic image for a threshold value or more.
 (第2実施形態)
 第1実施形態では、物質の統計情報(抽出対象の物質の含有率)が閾値以上含まれる一連のフレームを抽出範囲として特定したが、本実施形態では、放射線動画(放射線画像)のフレームのうち、物質の統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレームと、最後のフレームとで定められる範囲を抽出範囲として特定する構成を説明する。
(Second Embodiment)
In the first embodiment, a series of frames including the statistical information of substances (content ratio of substances to be extracted) equal to or more than a threshold is specified as the extraction range. However, in the present embodiment, A configuration in which the range defined by the first frame and the last frame in which the statistical information of the substance (content ratio of the substance to be extracted) is equal to or greater than the threshold is specified as the extraction range will be described.
 第2実施形態における放射線撮影システム100の構成は第1実施形態(図1)と同様である。第2実施形態では、フレーム抽出部105は、以下の図6に示す処理の流れで処理を行う。図6は、第2実施形態におけるフレーム抽出部105のフレーム抽出処理2002の流れを示す図であり、フレーム抽出処理2002は第1実施形態の図2で説明した処理シーケンスに対応する処理である。 The configuration of the radiation imaging system 100 in the second embodiment is the same as that in the first embodiment (FIG. 1). In the second embodiment, the frame extraction unit 105 performs processing according to the processing flow shown in FIG. FIG. 6 is a diagram illustrating a flow of the frame extraction process 2002 of the frame extraction unit 105 in the second embodiment, and the frame extraction process 2002 is a process corresponding to the process sequence described in FIG. 2 of the first embodiment.
 ステップS601において、フレーム抽出部105は、物質分解部103から得られた物質識別画像から、フレームごとに、抽出対象の物質がどれくらい含まれるかを計測する。フレーム抽出部105は、放射線が照射された照射野内の物質識別画像の画素値の合計を計算する。ここで、画素値は0.0から1.0の値であり、その物質がフレームに含まれていなければ画素値は0.0であり、物質がフレームに含まれていれば、画素値は0.0より大きく、1.0以下の値となる。 In step S601, the frame extraction unit 105 measures how much of the substance to be extracted is included for each frame from the substance identification image obtained from the substance decomposition unit 103. The frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation. Here, the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0.
 ステップS602において、フレーム抽出部105は、ステップS601で得られた、フレームにおける画素値の合計を照射野の画素数で除算し、各物質の統計情報(抽出対象の物質の含有率)を計算する。 In step S602, the frame extraction unit 105 divides the sum of the pixel values in the frame obtained in step S601 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. .
 次に、ステップS603において、フレーム抽出部105は、抽出対象として指定された物質の統計情報(抽出対象の物質の含有率)と閾値との比較により、指定された物質の統計情報が閾値以上含まれるフレームを特定する。フレーム抽出部105は、物質の含有率が一定の閾値以上含まれるフレームを抽出し、抽出したフレームに基づいてフレームリストを生成する。 Next, in step S603, the frame extraction unit 105 includes the statistical information of the specified substance that exceeds the threshold by comparing the statistical information of the substance specified as the extraction target (content ratio of the extraction target substance) with the threshold. Identify the frame to be played. The frame extraction unit 105 extracts frames that include a substance content rate equal to or greater than a certain threshold value, and generates a frame list based on the extracted frames.
 ステップS604において、フレーム抽出部105は、フレームリストの最初のフレーム番号と最後のフレーム番号により定まる範囲を一つの抽出範囲として設定する。すなわち、フレーム抽出部105は、ステップS603で生成したフレームリストから、最初のフレーム番号と最後のフレーム番号とを特定し、最初のフレーム番号と、最後のフレーム番号とにより定まるフレーム間の範囲を一つの抽出範囲として設定する。そして、フレーム抽出部105は、抽出範囲内の全てのフレームを抽出対象のフレームとして設定する。本ステップでは、抽出範囲において、物質の統計情報(抽出対象の物質の含有率)が閾値未満であっても、抽出対象のフレームとして設定される。 In step S604, the frame extraction unit 105 sets a range determined by the first frame number and the last frame number in the frame list as one extraction range. That is, the frame extraction unit 105 identifies the first frame number and the last frame number from the frame list generated in step S603, and sets a range between frames determined by the first frame number and the last frame number. Set as one extraction range. Then, the frame extraction unit 105 sets all frames within the extraction range as extraction target frames. In this step, even if the statistical information of the substance (content ratio of the substance to be extracted) is less than the threshold in the extraction range, it is set as the frame to be extracted.
 ステップS605において、フレーム抽出部105は、物質識別画像に基づいて生成した表示処理画像を取得する。例えば、フレーム抽出部105は、表示処理画像として、画像生成部104で生成された仮想単色放射線画像25を取得する。 In step S605, the frame extraction unit 105 acquires a display processing image generated based on the substance identification image. For example, the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
 そして、ステップS606において、フレーム抽出部105は、ステップS604で設定された抽出範囲のフレームに対応する仮想単色放射線画像のフレームを抽出し、DICOMで規定されているマルチフレーム画像をDICOM画像として生成する。フレーム抽出部105は、設定された抽出範囲のフレームと同じフレーム番号のフレームを、診断用の画像(仮想単色放射線画像)から取得し、取得したフレームに基づいてDICOM画像を生成する。 In step S606, the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame in the extraction range set in step S604, and generates a multi-frame image defined by DICOM as a DICOM image. . The frame extraction unit 105 acquires a frame having the same frame number as the frame of the set extraction range from a diagnostic image (virtual monochromatic radiation image), and generates a DICOM image based on the acquired frame.
 第1実施形態では、放射線画像において、抽出範囲の数が複数であれば、フレーム抽出部105は、各抽出範囲について複数のDICOM画像を生成したが、本実施形態では、フレーム抽出部105は、放射線画像のフレームのうち、物質の統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレームと、最後のフレームとで定められる範囲を一つの抽出範囲とし、抽出範囲内のフレームに基づいて一つのDICOM画像を生成する。 In the first embodiment, if there are a plurality of extraction ranges in the radiographic image, the frame extraction unit 105 generates a plurality of DICOM images for each extraction range. In this embodiment, the frame extraction unit 105 Of the radiographic image frames, the range defined by the first frame and the last frame where the statistical information of the substance (content rate of the substance to be extracted) is equal to or greater than the threshold is defined as one extraction range, and the frames within the extraction range One DICOM image is generated based on the above.
 図7は、図6のステップS604における、フレームの抽出範囲の決定方法を説明する図である。図7において、横軸は時間であり、各フレームにおける抽出対象の物質の含有率をハッチングで示している。フレーム抽出部105は、物質識別画像を構成するフレームのうち、統計情報が閾値以上となる最初のフレームと、閾値以上となる最後のフレームとにより定まる範囲を一つの抽出範囲として設定する。フレーム抽出部105は、抽出範囲に対応するフレームを、表示処理画像を構成するフレームから抽出する。例えば、図7のような統計情報(抽出対象の物質の含有率)の分布である場合、閾値以上となる最初のフレーム701を始点、閾値以上となる最後のフレーム702を終点とした抽出範囲703が一つの抽出範囲として設定される。すなわち、統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレーム701のフレーム番号(最初のフレーム番号)と、閾値以上となる最後のフレーム702のフレーム番号(最後のフレーム番号)とにより定まるフレーム間の範囲を一つの抽出範囲703として設定する。 FIG. 7 is a diagram for explaining a frame extraction range determination method in step S604 of FIG. In FIG. 7, the horizontal axis represents time, and the content rate of the substance to be extracted in each frame is indicated by hatching. The frame extraction unit 105 sets, as one extraction range, a range determined by a first frame in which statistical information is greater than or equal to a threshold and a last frame in which the statistical information is greater than or equal to the threshold. The frame extraction unit 105 extracts a frame corresponding to the extraction range from the frames constituting the display processing image. For example, in the case of the distribution of the statistical information (content ratio of the substance to be extracted) as shown in FIG. 7, the extraction range 703 has the first frame 701 that is equal to or higher than the threshold as the start point and the last frame 702 that is equal to or higher than the threshold as the end point. Is set as one extraction range. That is, the frame number (first frame number) of the first frame 701 in which the statistical information (content ratio of the substance to be extracted) is equal to or greater than the threshold, and the frame number (last frame number) of the last frame 702 that is equal to or greater than the threshold. A range between frames determined by the above is set as one extraction range 703.
 フレーム抽出部105は、抽出範囲703内の全てのフレームを抽出対象のフレームとして設定し、抽出範囲703において、物質の統計情報(抽出対象の物質の含有率)が閾値未満であっても、抽出対象のフレームとして抽出される。 The frame extraction unit 105 sets all the frames in the extraction range 703 as extraction target frames, and even if the substance statistical information (content ratio of the extraction target substance) is less than the threshold in the extraction range 703, the extraction is performed. Extracted as the target frame.
 本実施形態によれば、放射線画像において注目する物質が含まれているフレームを抽出することができる。エネルギーサブトラクション法の物質弁別技術を利用し、事前に指定した物質の統計情報(抽出対象の物質の含有率)をフレームごとに取得し、放射線画像のフレームのうち、物質の統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレームと、最後のフレームとで定められる範囲を抽出範囲とし、抽出対象となるフレーム間の連続性を維持しつつ抽出したフレームに基づく画像を保存用のデータとしてPACS12に送信することで、保存時のデータ量を節約するとともに、特定位置の画素情報の変化の計測結果によらず、放射線画像において注目する物質が閾値以上含まれているフレームを、精度よく抽出することが可能になる。 According to the present embodiment, it is possible to extract a frame containing a material of interest in a radiographic image. Using the material discrimination technology of the energy subtraction method, statistical information on the substance specified in advance (content ratio of the extraction target substance) is acquired for each frame, and the statistical information on the substance (of the extraction target in the radiographic image frame) is acquired. For the purpose of saving images based on the extracted frames while maintaining the continuity between the frames to be extracted, with the range defined by the first frame and the last frame having a substance content ratio) equal to or greater than the threshold as the extraction range By transmitting to the PACS 12 as data, it is possible to save the amount of data at the time of storage, and regardless of the measurement result of the change in pixel information at a specific position, a frame in which a substance of interest in the radiation image is included above the threshold value, It becomes possible to extract accurately.
 (第3実施形態)
 第1実施形態、第2実施形態では、エネルギーサブトラクション法の物質弁別技術を利用して、特定の物質の統計情報(抽出対象の物質の含有率)が閾値以上となる条件に基づいてフレームを抽出する構成について説明した。第3実施形態では、放射線画像に含まれる複数の物質の情報を表示部に表示させ、フレームを抽出する特定の物質を指定する構成について説明する。
(Third embodiment)
In the first embodiment and the second embodiment, frames are extracted based on the condition that the statistical information of the specific substance (content ratio of the substance to be extracted) is equal to or greater than the threshold by using the material discrimination technique of the energy subtraction method. The configuration to be described has been described. In the third embodiment, a configuration in which information of a plurality of substances included in a radiographic image is displayed on a display unit and a specific substance for extracting a frame is designated will be described.
 図8は、第3実施形態における放射線撮影システム100の機能構成を例示する図であり、放射線発生装置11および放射線撮影装置10を有する放射線撮影システム100の構成は第1実施形態(図1)と同様であり、放射線撮影装置10(図1)と同様の機能ブロックには、同一の参照番号を付している。 FIG. 8 is a diagram illustrating a functional configuration of the radiation imaging system 100 according to the third embodiment. The configuration of the radiation imaging system 100 including the radiation generation device 11 and the radiation imaging device 10 is the same as that of the first embodiment (FIG. 1). The same functional blocks as those in the radiation imaging apparatus 10 (FIG. 1) are denoted by the same reference numerals.
 図9は、第3実施形態における表示制御部801が表示制御を行う表示部の構成を例示する図である。表示制御部801は、表示処理画像(診断用の画像)を表示する画像表示エリア901と、各フレームにおける統計情報を放射線画像の撮影時間に合わせてグラフ表示するタイムライン表示エリア902と、を表示部に表示させる。表示制御部801は、画像生成部104から、診断用の画像について画像生成の完了を示す生成通知が入力されると、画像生成部104から診断用の画像(仮想単色放射線画像、または、平均エネルギー画像)を取得し、表示部の画像表示エリア901(図9)に表示する表示制御を行う。 FIG. 9 is a diagram illustrating a configuration of a display unit in which the display control unit 801 according to the third embodiment performs display control. The display control unit 801 displays an image display area 901 for displaying a display processed image (diagnosis image), and a timeline display area 902 for displaying statistical information in each frame in a graph according to the radiographic image capturing time. Display on the screen. When a generation notification indicating completion of image generation for a diagnostic image is input from the image generation unit 104 to the display control unit 801, a diagnostic image (virtual monochromatic radiation image or average energy) is input from the image generation unit 104. Display) is acquired and displayed in the image display area 901 (FIG. 9) of the display unit.
 また、表示制御部801は、フレーム抽出部105から、フレームごとに各物質の統計情報(抽出対象の物質の含有率)と、フレームの抽出範囲の情報を取得し、取得した情報を表示部のタイムライン表示エリア902(図9)に表示する表示制御を行う。タイムライン表示エリア902は、表示制御部801の制御に基づいて、それぞれの物質のフレームごとの統計情報(抽出対象の物質の含有率)を表示し、操作者がフレーム抽出のために抽出対象の物質を指定することができるユーザーインターフェースとして機能する。タイムライン表示エリア902では操作者がフレームを抽出する物質を指定することができ、指定された物質を示す指定統計情報をフレーム抽出部105へ送信する。このタイムライン表示エリア902は、物質リスト表示部903と、統計情報グラフ表示部904と、フレーム抽出範囲表示部905と、再生位置表示部906を含む。 In addition, the display control unit 801 acquires, from the frame extraction unit 105, statistical information of each substance (content ratio of the extraction target substance) and information on the extraction range of the frame for each frame, and displays the acquired information on the display unit. Display control is performed in the timeline display area 902 (FIG. 9). Based on the control of the display control unit 801, the timeline display area 902 displays statistical information (content ratio of the substance to be extracted) for each substance frame, and the operator can select the extraction target for frame extraction. It functions as a user interface that can specify substances. In the timeline display area 902, the operator can designate a substance from which a frame is extracted, and the designated statistical information indicating the designated substance is transmitted to the frame extraction unit 105. The timeline display area 902 includes a substance list display unit 903, a statistical information graph display unit 904, a frame extraction range display unit 905, and a reproduction position display unit 906.
 フレーム抽出部105は、物質識別画像を構成する各フレームについて、表示制御部801により指定された特定の物質に関する統計情報を求め、統計情報に基づいてフレームを抽出する。例えば、フレーム抽出部105は、物質識別画像を構成する各フレームについて、指定された特定の物質が含まれる割合を示す統計情報(例えば、各物質の含有率など)を求め、統計情報が一定以上の割合となるフレームを、物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像を生成する。フレーム抽出部105は、表示処理画像を構成するフレームから、統計情報が一定以上の割合となるフレームに対応するフレームを抽出して抽出画像を生成する。 The frame extraction unit 105 obtains statistical information about a specific substance designated by the display control unit 801 for each frame constituting the substance identification image, and extracts a frame based on the statistical information. For example, the frame extraction unit 105 obtains statistical information (for example, the content rate of each substance) indicating the ratio of the specified specific substance for each frame constituting the substance identification image, and the statistical information is equal to or greater than a certain level. The extracted image is generated by extracting the frame having the ratio of (2) from the frames constituting the display processing image generated based on the substance identification image. The frame extraction unit 105 extracts a frame corresponding to a frame whose statistical information has a certain ratio or more from the frames constituting the display processing image, and generates an extracted image.
 物質リスト表示部903は、物質の名称を示す物質名リストと、抽出対象の物質を指定する物質指定部とを有する。表示制御部801は、物質リスト表示部903に、フレーム抽出部105から取得した物質の物質名リストを表示する。物質リスト表示部903には、抽出対象の物質を指定する物質指定部として、チェックボックスが表示されており、操作者がチェックボックスに入力をすると、入力された物質がフレームの抽出対象の物質として指定される。表示制御部801は、指定された物質を示す指定統計情報をフレーム抽出部105へ送信する。フレーム抽出部105は、物質指定部で指定された物質ついて、フレームの抽出範囲を取得し、表示処理画像(診断用の画像)を構成するフレームから抽出範囲に対応するフレームを抽出した抽出画像を生成する。 The substance list display unit 903 has a substance name list indicating the names of substances and a substance designating part for designating substances to be extracted. The display control unit 801 displays a substance name list of substances acquired from the frame extraction unit 105 on the substance list display unit 903. The substance list display unit 903 displays a check box as a substance designating part for designating a substance to be extracted. When the operator inputs a check box, the input substance is used as a substance to be extracted in the frame. It is specified. The display control unit 801 transmits designated statistical information indicating the designated substance to the frame extracting unit 105. The frame extraction unit 105 acquires a frame extraction range for the substance designated by the substance designation unit, and extracts an extracted image obtained by extracting a frame corresponding to the extraction range from the frames constituting the display processing image (diagnosis image). Generate.
 表示制御部801は、統計情報グラフ表示部904に、フレーム抽出部105から取得した各物質の統計情報(抽出対象の物質の含有率)のグラフを表示する。表示制御部801は、物質の名称を示す物質名リストと、抽出対象の物質を指定する物質指定部とを、統計情報グラフ表示部904のグラフ表示に対して並べて表示させる。このような表示制御により、操作者は、各物質名と統計情報(抽出対象の物質の含有率)のグラフとを視覚的に対応付けて把握することが可能になる。 The display control unit 801 displays a graph of the statistical information (content rate of the substance to be extracted) of each substance acquired from the frame extraction unit 105 on the statistical information graph display unit 904. The display control unit 801 displays a substance name list indicating the name of the substance and a substance designating part for designating the substance to be extracted side by side with respect to the graph display of the statistical information graph display unit 904. By such display control, the operator can grasp each substance name and a graph of statistical information (content ratio of a substance to be extracted) in a visual association.
 また、表示制御部801は、統計情報グラフ表示部904のグラフ表示に、統計情報が一定以上の割合となるフレームの抽出範囲の表示を重ねて表示させる。すなわち、表示制御部801は、フレーム抽出部105から取得したフレームの抽出範囲(フレーム抽出範囲表示部905)を、統計情報グラフ表示部904のグラフ表示上に表示する。図9において、フレーム抽出範囲表示部905はハッチングで示されており、このような表示制御により、操作者は、全体のフレームにおける抽出範囲の分布を視覚により識別することが可能になる。 Also, the display control unit 801 displays the extraction range of frames in which the statistical information has a certain ratio or more on the graph display of the statistical information graph display unit 904. That is, the display control unit 801 displays the frame extraction range (the frame extraction range display unit 905) acquired from the frame extraction unit 105 on the graph display of the statistical information graph display unit 904. In FIG. 9, the frame extraction range display unit 905 is indicated by hatching, and such display control allows the operator to visually identify the distribution of the extraction range in the entire frame.
 タイムライン表示エリア902の再生ボタン920を操作者が押下すると、表示制御部801は、画像表示エリア901に表示している診断用の画像の動画再生を行い、停止ボタン930を操作者が押下すると動画再生を停止するように表示制御を行うことが可能である。表示制御部801は、画像表示エリア901に表示されている画像の再生位置を示す再生位置表示部906を、各統計情報(抽出対象の物質の含有率)のグラフに対して並べて表示する。このような表示制御により、画像の再生位置と、各物質の含有率との関係を視覚的に対応付けて把握することが可能になる。例えば、特定物質の統計情報(抽出対象の物質の含有率)に着目した場合、操作者は、どのフレーム(範囲)を再生すべきかを迅速に特定することが可能になる。 When the operator presses the playback button 920 in the timeline display area 902, the display control unit 801 performs video playback of the diagnostic image displayed in the image display area 901, and when the operator presses the stop button 930. It is possible to perform display control so as to stop moving image playback. The display control unit 801 displays a reproduction position display unit 906 indicating the reproduction position of the image displayed in the image display area 901 side by side with respect to each statistical information (content rate of substance to be extracted) graph. By such display control, it becomes possible to grasp the relationship between the reproduction position of the image and the content rate of each substance in a visually correlated manner. For example, when paying attention to statistical information (content ratio of a substance to be extracted) of a specific substance, the operator can quickly specify which frame (range) should be reproduced.
 図10は、第3実施形態におけるフレーム抽出部105のフレーム抽出処理の流れを示す図である。ステップS1001において、フレーム抽出部105は、物質分解部103から得られた物質識別画像から、フレームごとに、抽出対象の物質がどれくらい含まれるかを計測する。フレーム抽出部105は、放射線が照射された照射野内の物質識別画像の画素値の合計を計算する。ここで、画素値は0.0から1.0の値であり、その物質がフレームに含まれていなければ画素値は0.0であり、物質がフレームに含まれていれば、画素値は0.0より大きく、1.0以下の値となる。 FIG. 10 is a diagram showing a flow of frame extraction processing of the frame extraction unit 105 in the third embodiment. In step S <b> 1001, the frame extraction unit 105 measures how many substances to be extracted are included for each frame from the substance identification image obtained from the substance decomposition unit 103. The frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the irradiation field irradiated with radiation. Here, the pixel value is a value from 0.0 to 1.0. If the substance is not included in the frame, the pixel value is 0.0. If the substance is included in the frame, the pixel value is The value is greater than 0.0 and less than or equal to 1.0.
 ステップS1002において、フレーム抽出部105は、ステップS1001で得られた、フレームにおける画素値の合計を照射野の画素数で除算し、各物質の統計情報(抽出対象の物質の含有率)を計算する。 In step S1002, the frame extraction unit 105 divides the sum of the pixel values in the frame obtained in step S1001 by the number of pixels in the irradiation field, and calculates statistical information (content ratio of the substance to be extracted) of each substance. .
 ステップS1003において、フレーム抽出部105は、エネルギーサブトラクション法により物質分解部103で分解された各物質の名称を示す物質名リスト、各物質の統計情報(抽出対象の物質の含有率)、各物質について求めた抽出範囲のフレームリストを表示制御部801に送信する。 In step S1003, the frame extraction unit 105 determines a substance name list indicating the names of the substances decomposed by the substance decomposition unit 103 by the energy subtraction method, statistical information (content ratio of substances to be extracted) of each substance, and each substance. The frame list of the obtained extraction range is transmitted to the display control unit 801.
 ここで、フレーム抽出部105は、物質の含有率が一定の閾値以上含まれるフレームを抽出し、閾値以上となる一連のフレームを抽出範囲とすることが可能である。また、フレーム抽出部105は、統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレームのフレーム番号と、閾値以上となる最後のフレームのフレーム番号とにより定まる範囲を一つの抽出範囲として設定することも可能である。フレーム抽出部105は、各物質について抽出範囲を取得し、取得した抽出範囲に含まれるフレームのフレームリストを表示制御部801に送信する。 Here, the frame extraction unit 105 can extract a frame in which the content rate of the substance is included in a certain threshold or more, and can set a series of frames in which the content is equal to or more than the threshold as the extraction range. The frame extraction unit 105 extracts one range determined by the frame number of the first frame in which the statistical information (content ratio of the extraction target substance) is equal to or greater than the threshold and the frame number of the last frame in which the statistical information is equal to or greater than the threshold. It can also be set as a range. The frame extraction unit 105 acquires an extraction range for each substance, and transmits a frame list of frames included in the acquired extraction range to the display control unit 801.
 表示制御部801は、フレーム抽出部105から取得した情報に基づいて、タイムライン表示エリア902における表示制御を行う。タイムライン表示エリア902では操作者がフレームを抽出する物質を指定することが可能であり、表示制御部801は、指定された物質を示す指定統計情報をフレーム抽出部105へ送信する。 The display control unit 801 performs display control in the timeline display area 902 based on the information acquired from the frame extraction unit 105. In the timeline display area 902, the operator can designate a substance from which a frame is extracted, and the display control unit 801 transmits designated statistical information indicating the designated substance to the frame extraction unit 105.
 次に、ステップS1004において、フレーム抽出部105は、表示制御部801から受信した指定統計情報に対応する物質を、抽出対象の物質として特定する。フレーム抽出部105は、指定された物質について、抽出範囲のフレームリストを取得する。 Next, in step S1004, the frame extraction unit 105 identifies the substance corresponding to the specified statistical information received from the display control unit 801 as the extraction target substance. The frame extraction unit 105 acquires a frame list of the extraction range for the specified substance.
 ステップS1005において、フレーム抽出部105は、物質識別画像に基づいて生成した表示処理画像を取得する。例えば、フレーム抽出部105は、表示処理画像として、画像生成部104で生成された仮想単色放射線画像25を取得する。 In step S1005, the frame extraction unit 105 acquires a display processing image generated based on the substance identification image. For example, the frame extraction unit 105 acquires the virtual monochromatic radiation image 25 generated by the image generation unit 104 as the display processing image.
 そして、ステップS1006において、フレーム抽出部105は、ステップS1004で取得した抽出範囲のフレームリストに対応する仮想単色放射線画像のフレームを抽出し、DICOMで規定されているマルチフレーム画像をDICOM画像として生成する。フレーム抽出部105は、設定された抽出範囲のフレームと同じフレーム番号のフレームを、診断用の画像(仮想単色放射線画像)から取得し、取得したフレームに基づいてDICOM画像を生成する。 In step S1006, the frame extraction unit 105 extracts a virtual monochromatic radiation image frame corresponding to the frame list of the extraction range acquired in step S1004, and generates a multiframe image defined by DICOM as a DICOM image. . The frame extraction unit 105 acquires a frame having the same frame number as the frame of the set extraction range from a diagnostic image (virtual monochromatic radiation image), and generates a DICOM image based on the acquired frame.
 本実施形態によれば、放射線画像において注目する物質が含まれているフレームを抽出することができる。 According to the present embodiment, it is possible to extract a frame containing a material of interest in a radiographic image.
 また、エネルギーサブトラクション法の物質弁別技術を利用して、画面表示された各物質の統計情報(抽出対象の物質の含有率)等に基づき、操作者が指定した物質について、抽出範囲のフレームを診断に必要なフレームとして抽出し、抽出したフレームに基づく画像を保存用のデータとしてPACSに送信することで、保存時のデータ量を節約することができる。また、特定位置の画素情報(例えば、輝度や濃度などの画素値)の変化の計測結果によらず、放射線画像において注目する物質が閾値以上含まれているフレームを、精度よく抽出することが可能になる。 In addition, using the energy subtraction material discrimination technology, based on the statistical information (content rate of the substance to be extracted) of each substance displayed on the screen, the extraction range frame for the substance specified by the operator is diagnosed. By extracting the frames based on the extracted frames and transmitting the images based on the extracted frames to the PACS as storage data, the amount of data during storage can be saved. In addition, it is possible to accurately extract a frame that contains a substance of interest in a radiographic image that exceeds a threshold value, regardless of the measurement result of changes in pixel information at a specific position (for example, pixel values such as luminance and density). become.
 (第4実施形態)
 第4実施形態では、第3実施形態で説明した表示制御部801によるタイムライン表示エリアの表示制御について説明する。図11は第4実施形態における表示制御部801が表示制御を行うタイムライン表示エリア1100の構成例を示す図である。タイムライン表示エリア1100は、図9のタイムライン表示エリア902に加えて、閾値変更部1101を有する。
(Fourth embodiment)
In the fourth embodiment, display control of the timeline display area by the display control unit 801 described in the third embodiment will be described. FIG. 11 is a diagram illustrating a configuration example of a timeline display area 1100 in which the display control unit 801 according to the fourth embodiment performs display control. The timeline display area 1100 includes a threshold value changing unit 1101 in addition to the timeline display area 902 of FIG.
 閾値変更部1101は、統計情報(抽出対象の物質の含有率)との比較処理で使用する閾値の設定を表示するもので、表示制御部801は、統計情報との比較処理で使用する閾値の設定を表示する閾値変更部1101を表示部に表示させる。閾値変更部1101の表示において、表示制御部801は、統計情報グラフ表示部904のグラフ表示に、閾値変更部1101による閾値の設定表示を重ねて表示させる。 The threshold value changing unit 1101 displays the setting of the threshold value used in the comparison process with the statistical information (the content rate of the substance to be extracted). The display control unit 801 displays the threshold value used in the comparison process with the statistical information. A threshold value changing unit 1101 for displaying the setting is displayed on the display unit. In the display of the threshold changing unit 1101, the display control unit 801 displays the threshold setting display by the threshold changing unit 1101 on the graph display of the statistical information graph display unit 904.
 そして、表示制御部801は、閾値変更部1101の表示位置の変更に基づいて、設定されている閾値を変更する。表示制御部801は、マウス等の入力部を介した操作者の変更操作に基づいて、閾値変更部1101の表示位置を上下に変更することが可能である。閾値変更部1101の表示位置を変更することによって、設定されている閾値が変更される。表示制御部801は、現在設定されている閾値が変更されると、変更された新しい閾値をフレーム抽出部105に送信する。 The display control unit 801 changes the set threshold based on the change in the display position of the threshold change unit 1101. The display control unit 801 can change the display position of the threshold change unit 1101 up and down based on an operator's change operation via an input unit such as a mouse. By changing the display position of the threshold value changing unit 1101, the set threshold value is changed. When the currently set threshold is changed, the display control unit 801 transmits the changed new threshold to the frame extraction unit 105.
 フレーム抽出部105は、変更された閾値に基づいて、統計情報との比較処理を行い、統計情報が一定以上の割合となるフレームを、物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像を生成する。フレーム抽出部105は、表示制御部801から送信された閾値に基づいて、統計情報(抽出対象の物質の含有率)と、変更された閾値との比較処理を行う。フレーム抽出部105は、統計情報(抽出対象の物質の含有率)が、変更された閾値以上含まれるフレームを抽出し、閾値以上となる一連のフレームを抽出範囲とする。また、フレーム抽出部105は、統計情報(抽出対象の物質の含有率)が、変更された閾値以上となる最初のフレームのフレーム番号と、閾値以上となる最後のフレームのフレーム番号とにより定まる範囲を一つの抽出範囲として設定することも可能である。 The frame extraction unit 105 performs comparison processing with statistical information based on the changed threshold value, and constitutes a display processing image generated based on the substance identification image, in which the statistical information has a ratio of a certain level or more. An extracted image extracted from is generated. Based on the threshold value transmitted from the display control unit 801, the frame extraction unit 105 performs a comparison process between the statistical information (content ratio of the substance to be extracted) and the changed threshold value. The frame extraction unit 105 extracts frames in which the statistical information (content rate of the extraction target substance) is greater than or equal to the changed threshold, and sets a series of frames that are greater than or equal to the threshold as the extraction range. In addition, the frame extraction unit 105 determines the range in which the statistical information (content rate of the substance to be extracted) is determined by the frame number of the first frame that is greater than or equal to the changed threshold and the frame number of the last frame that is greater than or equal to the threshold. Can be set as one extraction range.
 フレーム抽出部105は、各物質について抽出範囲を取得し、取得した抽出範囲に含まれるフレームのリスト(フレームリスト)を表示制御部801に送信する。表示制御部801は、フレーム抽出部105から送信された抽出範囲のフレームリストに基づいて、タイムライン表示エリア902における抽出範囲の表示を変更する。図11において、抽出範囲1102と抽出範囲1103は、フレーム抽出部105から送信された抽出範囲のフレームリストに基づいて変更された抽出範囲である。 The frame extraction unit 105 acquires an extraction range for each substance, and transmits a list of frames (frame list) included in the acquired extraction range to the display control unit 801. The display control unit 801 changes the display of the extraction range in the timeline display area 902 based on the extraction range frame list transmitted from the frame extraction unit 105. In FIG. 11, an extraction range 1102 and an extraction range 1103 are extraction ranges that have been changed based on the extraction range frame list transmitted from the frame extraction unit 105.
 本実施形態によれば、操作者による閾値の変更が可能であり、フレーム抽出の微調整が可能である。表示された閾値変更部1101の表示位置を変更操作することにより、閾値の設定を任意に変更することができ、変更された閾値に基づいて、統計情報(抽出対象の物質の含有率)と閾値との比較処理を行うことができる。変更した閾値と統計情報との比較により抽出範囲を変更することができる。抽出範囲の変更により診断に必要なフレームを抽出することができる。抽出したフレームに基づく画像を保存用のデータとしてPACS12に送信することで、保存時のデータ量を節約することができる。 According to the present embodiment, the threshold value can be changed by the operator, and fine adjustment of the frame extraction is possible. By changing the display position of the displayed threshold value changing unit 1101, the setting of the threshold value can be arbitrarily changed. Based on the changed threshold value, statistical information (content ratio of the substance to be extracted) and the threshold value are changed. And comparison processing can be performed. The extraction range can be changed by comparing the changed threshold value with the statistical information. A frame necessary for diagnosis can be extracted by changing the extraction range. By transmitting an image based on the extracted frame to the PACS 12 as storage data, the amount of data at the time of storage can be saved.
 (第5実施形態)
 第5実施形態では、第3実施形態で説明した表示制御部801による画像表示エリアの表示制御について説明する。図12は第5実施形態における表示制御部801が表示制御を行う画像表示エリア1200の構成例を示す図である。画像表示エリア1200は、図9の画像表示エリア901に加えて、抽出エリア指定部1201を有する。
(Fifth embodiment)
In the fifth embodiment, display control of an image display area by the display control unit 801 described in the third embodiment will be described. FIG. 12 is a diagram illustrating a configuration example of an image display area 1200 in which the display control unit 801 according to the fifth embodiment performs display control. The image display area 1200 includes an extraction area designation unit 1201 in addition to the image display area 901 of FIG.
 抽出エリア指定部1201は、統計情報(抽出対象の物質の含有率)を算出するための画素範囲を指定する。すなわち、抽出エリア指定部1201は、フレーム抽出部105が統計情報(抽出対象の物質の含有率)を算出する際に、物質識別画像の画素値の合計を取得するための画素範囲を指定する。 The extraction area designation unit 1201 designates a pixel range for calculating statistical information (content rate of a substance to be extracted). That is, the extraction area designation unit 1201 designates a pixel range for obtaining the sum of pixel values of the substance identification image when the frame extraction unit 105 calculates statistical information (content ratio of the substance to be extracted).
 表示制御部801は、統計情報を算出するための画素範囲を指定する抽出エリア指定部1201を表示部に表示させ、フレーム抽出部105は、抽出エリア指定部1201で指定された画像範囲の画素値の情報に基づいて、統計情報を取得する。抽出エリア指定部1201の表示において、表示制御部801は、画像表示エリア1200に表示されている表示処理画像(診断用の画像)に、抽出エリア指定部1201で指定された画素範囲を重ねて表示させる。 The display control unit 801 causes the display unit to display an extraction area specification unit 1201 that specifies a pixel range for calculating statistical information, and the frame extraction unit 105 sets the pixel value of the image range specified by the extraction area specification unit 1201. Statistical information is acquired based on the information. In the display of the extraction area designation unit 1201, the display control unit 801 displays the pixel range designated by the extraction area designation unit 1201 on the display processing image (diagnosis image) displayed in the image display area 1200. Let
 表示制御部801は、マウス等の入力部を介した操作者の指定操作に基づいて、抽出エリア指定部1201の表示範囲を変更することが可能である。抽出エリア指定部1201の表示範囲を変更設定することによって、設定されている画素範囲が変更される。初期値として設定されている画素範囲は、照射野を画素範囲とするもので、抽出エリア指定部1201による変更設定が行われなければ、初期値の設定である照射野が画素範囲として維持される。画素値の合計をする画素範囲を操作者が指定することにより、診断に必要なフレームを抽出するための追加条件とすることができる。 The display control unit 801 can change the display range of the extraction area designation unit 1201 based on an operator's designation operation via an input unit such as a mouse. By changing and setting the display range of the extraction area specifying unit 1201, the set pixel range is changed. The pixel range set as the initial value has the irradiation field as the pixel range, and if the change setting by the extraction area designation unit 1201 is not performed, the irradiation field that is the initial value setting is maintained as the pixel range. . When the operator designates a pixel range in which the pixel values are summed, an additional condition for extracting a frame necessary for diagnosis can be set.
 表示制御部801は、現在設定されている画素範囲が変更されると、変更された新しい画素範囲をフレーム抽出部105に送信する。フレーム抽出部105は、表示制御部801から送信された変更後の画素範囲に基づいて、統計情報(抽出対象の物質の含有率)を計算する。 When the currently set pixel range is changed, the display control unit 801 transmits the changed new pixel range to the frame extraction unit 105. The frame extraction unit 105 calculates statistical information (content ratio of the substance to be extracted) based on the changed pixel range transmitted from the display control unit 801.
 フレーム抽出部105は、物質識別画像から、フレームごとに、指定された画素範囲内の物質識別画像の画素値の合計を、画素範囲の画素数で除算した結果を統計情報として取得する。まず、フレーム抽出部105は、フレームごとに、変更後の画素範囲内の物質識別画像の画素値の合計を計算する。そして、フレーム抽出部105は、フレームにおける画素値の合計を画素範囲の画素数で除算し、各物質の統計情報(抽出対象の物質の含有率)を計算する。 The frame extraction unit 105 acquires, as statistical information, the result of dividing the sum of the pixel values of the substance identification image within the designated pixel range by the number of pixels in the pixel range from the substance identification image for each frame. First, the frame extraction unit 105 calculates the sum of the pixel values of the substance identification image in the changed pixel range for each frame. Then, the frame extraction unit 105 divides the sum of the pixel values in the frame by the number of pixels in the pixel range, and calculates statistical information (content ratio of the substance to be extracted) of each substance.
 フレーム抽出部105は、変更後の画素範囲に基づいて算出した統計情報(抽出対象の物質の含有率)と閾値との比較結果に基づいて、フレームの抽出範囲を設定することが可能である。フレームの抽出範囲の設定方法としては、第1実施形態で説明したように、統計情報(抽出対象の物質の含有率)が閾値以上となる一連のフレームを抽出範囲とすることが可能である。また、第2実施形態で説明したように、また、統計情報(抽出対象の物質の含有率)が閾値以上となる最初のフレームのフレーム番号と、閾値以上となる最後のフレームのフレーム番号とにより定まる範囲を一つの抽出範囲として設定することも可能である。 The frame extraction unit 105 can set the extraction range of the frame based on the comparison result between the statistical information (content rate of the substance to be extracted) calculated based on the changed pixel range and the threshold value. As a method for setting a frame extraction range, as described in the first embodiment, a series of frames in which statistical information (content ratio of a substance to be extracted) is equal to or greater than a threshold can be set as the extraction range. Further, as described in the second embodiment, the statistical information (the content rate of the substance to be extracted) is the frame number of the first frame that is equal to or greater than the threshold value, and the frame number of the last frame that is equal to or greater than the threshold value. It is also possible to set a fixed range as one extraction range.
 フレーム抽出部105は、エネルギーサブトラクション法により物質分解部103で分解された各物質の名称を示す物質名リスト、変更後の画素範囲に基づいて算出した各物質の統計情報(抽出対象の物質の含有率)、各物質について求めた抽出範囲のフレームリストを表示制御部801に送信する。表示制御部801は、フレーム抽出部105から送信された情報に基づいて、タイムライン表示エリア(図9の902、図11の1100)の表示制御を行うことが可能である。 The frame extracting unit 105 includes a substance name list indicating the names of the substances decomposed by the substance decomposing unit 103 by the energy subtraction method, statistical information of each substance calculated based on the changed pixel range (contains the contents of the substance to be extracted) The frame list of the extraction range obtained for each substance is transmitted to the display control unit 801. The display control unit 801 can perform display control of the timeline display area (902 in FIG. 9 and 1100 in FIG. 11) based on the information transmitted from the frame extraction unit 105.
 本実施形態によれば、表示された抽出エリア指定部1201の表示範囲を変更することにより、操作者が注目している領域について、統計情報(抽出対象の物質の含有率)を算出する際に使用する画素範囲の設定を任意に変更することができ、変更された画素範囲に基づいて算出した統計情報(抽出対象の物質の含有率)と閾値との比較処理を行うことができる。比較処理の結果により求めた抽出範囲により、操作者が注目している領域に関し、診断に必要なフレームを抽出することができる。抽出したフレームに基づく画像を保存用のデータとしてPACS12に送信することで、保存時のデータ量を節約することができる。 According to this embodiment, by changing the display range of the displayed extraction area designating unit 1201, when calculating statistical information (content ratio of a substance to be extracted) for a region that the operator is paying attention to. The setting of the pixel range to be used can be arbitrarily changed, and a comparison process between the statistical information calculated based on the changed pixel range (content ratio of the substance to be extracted) and the threshold value can be performed. Based on the extraction range obtained from the result of the comparison process, it is possible to extract a frame necessary for the diagnosis with respect to the region focused by the operator. By transmitting an image based on the extracted frame to the PACS 12 as storage data, the amount of data at the time of storage can be saved.
 (その他の実施形態)
 本発明は、上述の実施形態の1以上の機能を実現するプログラムを、ネットワーク又は記憶媒体を介してシステム又は装置に供給し、そのシステム又は装置のコンピュータにおける1つ以上のプロセッサーがプログラムを読出し実行する処理でも実現可能である。また、1以上の機能を実現する回路(例えば、ASIC)によっても実現可能である。
(Other embodiments)
The present invention supplies a program that realizes one or more functions of the above-described embodiments to a system or apparatus via a network or a storage medium, and one or more processors in a computer of the system or apparatus read and execute the program This process can be realized. It can also be realized by a circuit (for example, ASIC) that realizes one or more functions.
 本発明は上記実施の形態に制限されるものではなく、本発明の精神及び範囲から離脱することなく、様々な変更及び変形が可能である。従って、本発明の範囲を公にするために、以下の請求項を添付する。 The present invention is not limited to the above embodiment, and various changes and modifications can be made without departing from the spirit and scope of the present invention. Therefore, in order to make the scope of the present invention public, the following claims are attached.
 本願は、2018年5月25日提出の日本国特許出願特願2018-100861を基礎として優先権を主張するものであり、その記載内容の全てを、ここに援用する。 This application claims priority based on Japanese Patent Application No. 2018-1000086 filed on May 25, 2018, the entire contents of which are incorporated herein by reference.
 10:放射線撮影装置、11:放射線発生装置、12:PACS
 101:放射線撮影部、102:画像取得部、103:物質分解部、
 104:画像生成部、105:フレーム抽出部、106:画像通信部、
 107、801:表示制御部、901:画像表示エリア、
 902:タイムライン表示エリア、903:物質リスト表示、
 904:含有率グラフ表示、905:フレーム抽出範囲表示、
 906:再生位置表示、1100:タイムライン表示エリア、
 1101:閾値変更部、1102、1103:抽出範囲
 1200:画像表示エリア、1201:抽出エリア指定部
10: Radiation imaging device, 11: Radiation generator, 12: PACS
101: Radiation imaging unit, 102: Image acquisition unit, 103: Substance decomposition unit,
104: Image generation unit, 105: Frame extraction unit, 106: Image communication unit,
107, 801: display control unit, 901: image display area,
902: Timeline display area, 903: Substance list display,
904: content rate graph display, 905: frame extraction range display,
906: Playback position display, 1100: Timeline display area,
1101: Threshold change unit, 1102, 1103: Extraction range 1200: Image display area, 1201: Extraction area designation unit

Claims (29)

  1. 異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成手段と、
     前記物質識別画像を構成する各フレームについて、特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出手段と、
     を備えることを特徴とする放射線撮影装置。
    Generating means for generating a substance identification image showing a distribution of a plurality of substances included in a radiographic image taken with different radiation energies;
    For each frame constituting the substance identification image, obtaining statistical information on a specific substance, extracting means for extracting a frame based on the statistical information;
    A radiation imaging apparatus comprising:
  2.  前記抽出手段は、前記物質識別画像を構成するフレームから、前記統計情報が一定の閾値以上含まれるフレームを抽出し、閾値以上となる一連のフレームを抽出範囲として設定することを特徴とする請求項1に記載の放射線撮影装置。 The extraction means extracts a frame in which the statistical information is included in a certain threshold or more from frames constituting the substance identification image, and sets a series of frames in which the statistical information is over the threshold as an extraction range. The radiation imaging apparatus according to 1.
  3.  前記抽出手段は、前記物質識別画像を構成するフレームのうち、前記統計情報が閾値以上となる最初のフレームと、閾値以上となる最後のフレームとにより定まる範囲を一つの抽出範囲として設定することを特徴とする請求項1に記載の放射線撮影装置。 The extraction means sets, as one extraction range, a range determined by a first frame in which the statistical information is greater than or equal to a threshold value and a last frame in which the statistical information is greater than or equal to a threshold value among frames constituting the substance identification image. The radiographic apparatus according to claim 1, wherein
  4.  前記抽出手段は、前記物質識別画像を構成する各フレームについて、特定の物質が含まれる割合を示す前記統計情報を求め、前記統計情報が一定以上の割合となるフレームを、前記物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像を生成することを特徴とする請求項3に記載の放射線撮影装置。 The extraction means obtains the statistical information indicating a ratio of a specific substance contained in each frame constituting the substance identification image, and based on the substance identification image, a frame in which the statistical information has a certain ratio or more. The radiation imaging apparatus according to claim 3, wherein an extracted image extracted from a frame constituting the display processing image generated in this way is generated.
  5.  前記抽出手段は、前記抽出範囲に対応するフレームを、前記表示処理画像を構成するフレームから抽出することを特徴とする請求項4に記載の放射線撮影装置。 The radiation imaging apparatus according to claim 4, wherein the extraction unit extracts a frame corresponding to the extraction range from a frame constituting the display processing image.
  6.  前記複数の物質のそれぞれについて生成した前記物質識別画像に基づいて、前記表示処理画像を生成する画像生成手段を更に備えることを特徴とする請求項4または5に記載の放射線撮影装置。 6. The radiation imaging apparatus according to claim 4, further comprising image generation means for generating the display processing image based on the substance identification image generated for each of the plurality of substances.
  7.  前記画像生成手段は、前記放射線の一つのエネルギー成分に基づいて、前記複数の物質のうち特定の物質を強調する画像を前記表示処理画像として生成することを特徴とする請求項6に記載の放射線撮影装置。 The radiation according to claim 6, wherein the image generation unit generates an image that emphasizes a specific substance among the plurality of substances as the display processing image based on one energy component of the radiation. Shooting device.
  8.  前記表示処理画像には、仮想単色放射線画像が含まれることを特徴とする請求項4乃至7のいずれか1項に記載の放射線撮影装置。 The radiation imaging apparatus according to claim 4, wherein the display processing image includes a virtual monochromatic radiation image.
  9.  前記抽出手段は、前記抽出画像に基づいて、DICOM規格に基づいたDICOM画像を生成することを特徴とする請求項4乃至8のいずれか1項に記載の放射線撮影装置。 9. The radiographic apparatus according to claim 4, wherein the extraction unit generates a DICOM image based on a DICOM standard based on the extracted image.
  10.  前記抽出手段は、前記物質識別画像から、フレームごとに、前記放射線が照射された照射野内の物質識別画像の画素値の合計を、照射野の画素数で除算した結果を前記統計情報として取得することを特徴とする請求項1乃至9のいずれか1項に記載の放射線撮影装置。 The extraction means acquires, as the statistical information, a result of dividing the sum of pixel values of the substance identification image in the irradiation field irradiated with the radiation by the number of pixels of the irradiation field for each frame from the substance identification image. The radiation imaging apparatus according to claim 1, wherein:
  11.  前記抽出手段は、前記放射線画像と、前記放射線画像に対する前記物質ごとの抽出範囲を示すインデックス情報とを、組み合せて記憶手段に記憶することを特徴とする請求項1乃至10のいずれか1項に記載の放射線撮影装置。 The said extraction means memorize | stores in a memory | storage means combining the said radiographic image and the index information which shows the extraction range for every said substance with respect to the said radiographic image in any one of Claim 1 thru | or 10 characterized by the above-mentioned. The radiation imaging apparatus described.
  12.  異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成手段と、
     前記放射線画像に含まれる複数の物質の情報を表示手段に表示させ、フレームを抽出する特定の物質を指定する表示制御手段と、
     前記物質識別画像を構成する各フレームについて、前記指定された特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出手段と、
     を備えることを特徴とする放射線撮影装置。
    Generating means for generating a substance identification image showing a distribution of a plurality of substances included in a radiographic image taken with different radiation energies;
    Display information on a plurality of substances included in the radiation image is displayed on a display means, and a display control means for designating a specific substance for extracting a frame;
    For each frame constituting the substance identification image, extraction means for obtaining statistical information on the specified specific substance and extracting a frame based on the statistical information;
    A radiation imaging apparatus comprising:
  13.  前記表示制御手段は、前記統計情報との比較処理で使用する閾値の設定を表示する閾値変更手段を前記表示手段に表示させ、
     前記表示制御手段は、前記閾値変更手段の表示位置の変更に基づいて、設定されている閾値を変更することを特徴とする請求項12に記載の放射線撮影装置。
    The display control means causes the display means to display a threshold value changing means for displaying a setting of a threshold value used in the comparison process with the statistical information,
    The radiation imaging apparatus according to claim 12, wherein the display control unit changes a set threshold value based on a change in a display position of the threshold value changing unit.
  14.  前記抽出手段は、前記物質識別画像を構成する各フレームについて、前記指定された特定の物質が含まれる割合を示す前記統計情報を求め、前記統計情報が一定以上の割合となるフレームを、前記物質識別画像に基づいて生成した表示処理画像を構成するフレームから抽出した抽出画像を生成することを特徴とする請求項13に記載の放射線撮影装置。 The extraction means obtains the statistical information indicating a ratio of the specified specific substance included in each frame constituting the substance identification image, and determines a frame in which the statistical information has a certain ratio or more as the substance. The radiographic apparatus according to claim 13, wherein an extracted image extracted from a frame constituting a display processing image generated based on the identification image is generated.
  15.  前記抽出手段は、前記変更された閾値に基づいて、前記統計情報との比較処理を行い、
     前記統計情報が一定以上の割合となるフレームを、前記表示処理画像を構成するフレームから抽出した抽出画像を生成することを特徴とする請求項14に記載の放射線撮影装置。
    The extraction means performs a comparison process with the statistical information based on the changed threshold value,
    The radiographic apparatus according to claim 14, wherein an extracted image is generated by extracting a frame in which the statistical information has a certain ratio or more from a frame constituting the display processing image.
  16.  前記表示制御手段は、
     前記表示処理画像を表示する画像表示エリアと、各フレームにおける前記統計情報を前記放射線画像の撮影時間に合わせてグラフ表示するタイムライン表示エリアと、を前記表示手段に表示させることを特徴とする請求項14または15に記載の放射線撮影装置。
    The display control means includes
    The display means displays an image display area for displaying the display processed image and a timeline display area for displaying the statistical information in each frame in a graph according to the radiographic image capturing time. Item 16. The radiographic apparatus according to Item 14 or 15.
  17.  前記表示制御手段は、前記グラフ表示に、前記閾値変更手段による閾値の設定表示を重ねて表示させることを特徴とする請求項16に記載の放射線撮影装置。 17. The radiation imaging apparatus according to claim 16, wherein the display control unit displays a threshold setting display by the threshold changing unit on the graph display.
  18.  前記表示制御手段は、前記グラフ表示に、前記統計情報が一定以上の割合となるフレームの抽出範囲の表示を重ねて表示させることを特徴とする請求項16または17に記載の放射線撮影装置。 The radiographic imaging apparatus according to claim 16 or 17, wherein the display control means displays the extraction range of a frame in which the statistical information has a certain ratio or more on the graph display.
  19.  前記表示制御手段は、前記物質の名称を示す物質名リストと、抽出対象の物質を指定する物質指定部とを、前記グラフ表示に対して並べて表示させることを特徴とする請求項16乃至18のいずれか1項に記載の放射線撮影装置。 The display control means displays a substance name list indicating the name of the substance and a substance designating unit for designating a substance to be extracted side by side with respect to the graph display. The radiation imaging apparatus according to any one of the above.
  20.  前記抽出手段は、前記物質指定部で指定された物質ついて、前記フレームの抽出範囲を取得し、前記表示処理画像を構成するフレームから前記抽出範囲に対応するフレームを抽出した抽出画像を生成することを特徴とする請求項19に記載の放射線撮影装置。 The extraction means acquires an extraction range of the frame for the substance designated by the substance designation unit, and generates an extraction image obtained by extracting a frame corresponding to the extraction range from frames constituting the display processing image. The radiographic apparatus according to claim 19.
  21.  前記表示制御手段は、前記統計情報を算出するための画素範囲を指定する抽出エリア指定手段を前記表示手段に表示させ、
     前記抽出手段は、前記抽出エリア指定手段で指定された画像範囲の画素値の情報に基づいて、前記統計情報を取得することを特徴とする請求項16に記載の放射線撮影装置。
    The display control means causes the display means to display an extraction area designation means for designating a pixel range for calculating the statistical information,
    The radiation imaging apparatus according to claim 16, wherein the extraction unit acquires the statistical information based on pixel value information of an image range designated by the extraction area designation unit.
  22.  前記表示制御手段は、前記画像表示エリアに表示されている前記表示処理画像に、前記抽出エリア指定手段で指定された画素範囲を重ねて表示させることを特徴とする請求項21に記載の放射線撮影装置。 The radiographic imaging according to claim 21, wherein the display control means causes the display-processed image displayed in the image display area to overlap and display the pixel range specified by the extraction area specifying means. apparatus.
  23.  前記抽出手段は、前記物質識別画像から、フレームごとに、前記指定された画素範囲内の物質識別画像の画素値の合計を、画素範囲の画素数で除算した結果を前記統計情報として取得することを特徴とする請求項21または22に記載の放射線撮影装置。 The extraction means acquires, as the statistical information, a result of dividing the sum of pixel values of the substance identification image in the designated pixel range by the number of pixels in the pixel range from the substance identification image for each frame. The radiation imaging apparatus according to claim 21 or 22,
  24.  前記物質識別画像は、前記物質の実効原子番号又は面密度に基づいて生成されることを特徴とする請求項1乃至23のいずれか1項に記載の放射線撮影装置。 24. The radiographic apparatus according to claim 1, wherein the substance identification image is generated based on an effective atomic number or surface density of the substance.
  25.  異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成手段と、
     前記物質識別画像を構成する各フレームについて、特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出手段と、
     を備えることを特徴とする放射線撮影システム。
    Generating means for generating a substance identification image showing a distribution of a plurality of substances included in a radiographic image taken with different radiation energies;
    For each frame constituting the substance identification image, obtaining statistical information on a specific substance, extracting means for extracting a frame based on the statistical information;
    A radiation imaging system comprising:
  26.  異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成手段と、
     前記放射線画像に含まれる複数の物質の情報を表示手段に表示させ、フレームを抽出する特定の物質を指定する表示制御手段と、
     前記物質識別画像を構成する各フレームについて、前記指定された特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出手段と、
     を備えることを特徴とする放射線撮影システム。
    Generating means for generating a substance identification image showing a distribution of a plurality of substances included in a radiographic image taken with different radiation energies;
    Display information on a plurality of substances included in the radiation image is displayed on a display means, and a display control means for designating a specific substance for extracting a frame;
    For each frame constituting the substance identification image, extraction means for obtaining statistical information on the specified specific substance and extracting a frame based on the statistical information;
    A radiation imaging system comprising:
  27.  放射線撮影装置の放射線撮影方法であって、
     異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成工程と、
     前記物質識別画像を構成する各フレームについて、特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出工程と、
     を有することを特徴とする放射線撮影方法。
    A radiation imaging method for a radiation imaging apparatus, comprising:
    A generation step of generating a substance identification image indicating a distribution of a plurality of substances included in a radiographic image captured with energy of different radiation;
    For each frame constituting the substance identification image, an extraction step for obtaining statistical information on a specific substance and extracting a frame based on the statistical information;
    A radiation imaging method comprising:
  28.  放射線撮影装置の放射線撮影方法であって、
     異なる放射線のエネルギーで撮影した放射線画像に含まれる複数の物質についての分布を示す物質識別画像を生成する生成工程と、
     前記放射線画像に含まれる複数の物質の情報を表示手段に表示させ、フレームを抽出する特定の物質を指定する表示制御工程と、
     前記物質識別画像を構成する各フレームについて、前記指定された特定の物質に関する統計情報を求め、前記統計情報に基づいてフレームを抽出する抽出工程と、
     を有することを特徴とする放射線撮影方法。
    A radiation imaging method for a radiation imaging apparatus, comprising:
    A generation step of generating a substance identification image indicating a distribution of a plurality of substances included in a radiographic image captured with energy of different radiation;
    A display control step for displaying information on a plurality of substances included in the radiation image on a display unit and designating a specific substance for extracting a frame;
    For each frame constituting the substance identification image, obtaining statistical information on the specified specific substance, and extracting the frame based on the statistical information;
    A radiation imaging method comprising:
  29.  コンピュータを、請求項1乃至23の何れか1項に記載の放射線撮影装置の各手段として機能させるためのプログラム。 A program for causing a computer to function as each unit of the radiation imaging apparatus according to any one of claims 1 to 23.
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