WO2019098207A1

WO2019098207A1 - Body fluid analysis device

Info

Publication number: WO2019098207A1
Application number: PCT/JP2018/042033
Authority: WO
Inventors: 良下北; 達之藤田; 貴澤田; 太介山内
Original assignee: ジーニアルライト株式会社
Priority date: 2017-11-14
Filing date: 2018-11-13
Publication date: 2019-05-23

Abstract

The present invention provides a body fluid analysis device that makes it possible to analyze a body fluid such as urine more accurately than by visual observation and that can reduce the burdens of medical workers, etc. A body fluid analysis device 100 that: shines light at a body fluid in a translucent tube T1 and analyzes the body fluid on the basis of the light that passes through the tube T1. The body fluid analysis device 100 comprises a base 1, an attachment 2 that is attached to the base 1 such that the tube T1 is sandwiched in the radial direction thereof between the attachment 2 and the base 1, a light-emitting element L that is provided to the base 1 or the attachment 2, and a light-receiving element D that is provided to the base 1 or the attachment 2. When the attachment 2 has been attached to the base 1, the light-emitting element L and the light-receiving element D are arranged between the base 1 and the attachment 2 so as to sandwich the tube T1 in the radial direction, or the light-emitting element L and the light-receiving element D are both arranged on the base 1 or on the attachment 2.

Description

Body fluid analyzer

The present invention relates to a body fluid analyzer that irradiates light onto body fluid contained in a translucent tube and analyzes the body fluid based on the light passing through the body fluid.

For example, for patients who undergo surgery under general anesthesia or who can not move from the bed for a long period of time, place a balloon catheter in the bladder and store the urine collected from the bladder in the urine bag There is. Such a urine bag (uro bag) has a urinary duct connected to the outer end of the balloon catheter, a reservoir connected to the urinary duct where urine can be stored, and urine accumulated in a fixed amount in the reservoir. And a discharge pipe for discharge and processing (see Patent Document 1).

By the way, when a balloon catheter is indwelled in the bladder, in particular in the case of a patient whose immunity is weakened, there is a possibility that inflammation due to bacterial infection or the like may occur in the bladder and the kidney connected thereto. For this reason, urine volume and urine blood subdivision are checked by a nurse to confirm whether normal kidney function is maintained.

However, it should be done only by the doctor whether the latent blood level may be left as it is by visually comparing the color of the urine with the 6-step color sample, or if it is the color of the urine that has no problem with nurses alone. The nurse must determine if it is the color of urine that must be treated to

The difference in the color of urine, especially when it can be handled only by a nurse and when it requires medical treatment by a doctor, is very subtle and may be difficult for the nurse to judge. For example, if you look at safety and always call a doctor if you are vague, the doctor will not be able to take care of patients who do not need to be in charge of the doctor, and other serious patients will not be able to reach your hand, etc. Valuable medical resources may be wasted. However, there is a possibility that the condition of the patient may be deteriorated if the nurse alone deals with the case where the medical practice by the doctor is necessary.

JP 2002-156376 A

The present invention has been made in view of the problems as described above, and it is possible to analyze body fluid such as urine more accurately than by visual observation, and it is possible to reduce, for example, the burden on medical workers. Intended to provide.

That is, the body fluid analyzer according to the present invention is a body fluid analyzer which irradiates light to body fluid in a translucent tube and analyzes the body fluid based on the light passing through the tube, the base And an attachment attached to the base such that the tube is sandwiched in the radial direction between the base, a light emitting element provided on either the base or the attachment, the base or the base A light receiving element provided on any of the attachments, the light emitting element and the light receiving element radially extending the tube between the base and the attachment in a state where the attachment is attached to the base Are placed in such a way as to sandwich the base, or the base or the attach Characterized in that both of the light emitting element and the light-emitting element in one of cement is placed.

Here, the body fluid is a concept including not only various liquids possessed by the living body but also liquids excreted and secreted outside the body.

If it is such, the light emitting element and the light receiving element can be positioned at a position suitable for measuring a body fluid, simply by attaching the tube so as to sandwich the base and the attachment.

Furthermore, the light emitting element or the light receiving element may be separated by a predetermined distance from the outer surface of the tube or a predetermined contact state may be realized by sandwiching the tube between the base and the attachment. it can. Therefore, an optical system suitable for reducing the influence of light passing through the tube and the influence of other stray light, or sufficiently detecting the light passing through the body fluid can be realized with good reproducibility. Therefore, even when a nurse who is not familiar with the assembly of an optical system or a machine attaches the base and the attachment to the tube, an instrument error in the analysis of the body fluid hardly occurs.

From these facts, it becomes possible to accurately analyze even non-contact bodily fluid in the tube based on the light detected by the light receiving element, and, for example, the degree of occult blood etc. which was conventionally determined visually by a nurse It will be possible to automate the judgment and to significantly reduce the burden on the medical site.

In addition, according to the present invention, it is possible to retrofit a body fluid analyzer to a tube through which body fluid flows in a conventional medical instrument etc., and to optically measure body fluid flowing in or staying in the tube. Analysis is possible.

The tube does not move with respect to its extending direction or circumferential direction to allow continuous analysis of body fluid at the same location, and between the light emitting element or the light receiving element and the outer surface of the tube The attachment comprises a contact surface that contacts the outer surface of the tube, such that the contact or separation distance is realized to be suitable for body fluid analysis, the attachment relative to the base The tube may be configured to be pressed against the base in the attached state.

In order for the light emitting element or the light receiving element to be in contact with the outer surface of the tube so that generation or detection of stray light by the tube can be reduced, the attachment is of the light emitting element or the light receiving element. It is sufficient that at least a part thereof is configured to be substantially flush with the contact surface.

The tube through which the body fluid used in the medical device flows may be bent. Even in such a case, the tube can be fixed in a predetermined posture or direction simply by sandwiching the tube between the base and the attachment, and light can be made to reach the light receiving element from the light emitting element, and accurate bodily fluid The base is provided with a groove into which the tube is fitted, and the light emitted from the light emitting element is allowed to pass through the bottom of the groove so that a state suitable for realizing the analysis of It is sufficient that the passage hole is formed.

In order for the optical axis of the light emitting element to easily fit to the light receiving element, the base itself comprises a housing portion into which the attachment is fitted, and the attachment is fitted into the housing portion The light receiving element may be disposed on the optical axis of the light emitting element.

In order to make it difficult to detect external light other than light emitted from the light emitting element with respect to the light receiving element and to improve analysis accuracy of body fluid, the base is attached to the main body to which the attachment is attached. , And a protruding portion that protrudes outward from the main body along the extending direction of the groove, and a portion of the groove is formed to cover at least the protruding portion of the base It is sufficient if the cover further includes

To ensure that the attachment is pressed against the outer surface of the tube with a predetermined force, so that an ideal contact is achieved in the analysis of body fluid, between the base and the cover An engaging structure formed, wherein the cover is configured to cover the main body portion of the base and the attachment attached to the main body portion of the base; The cover may be configured to press the attachment toward the base in a state where the cover is engaged with the base.

Even if the amount of body fluid flowing in the tube is small, the groove may be curved to temporarily stay between the light emitting element and the light receiving element to allow light to pass through the body fluid for analysis. It should just be formed.

As a specific configuration for facilitating temporary retention in the body fluid analyzer when analyzing body fluid flowing through the tube, the groove is vertical in a use state in which the light receiving element receives light passing through the tube. What is formed to be convex downward with respect to the direction is mentioned.

In order to facilitate the presence of body fluid on the optical axis of the light emitting element and to make it difficult for a state where nothing is analyzed to occur, the groove has a vertex in the main body near the optical axis of the light emitting element It should just be formed.

In the case of a body fluid analyzer further including a urine analysis unit for analyzing urine based on the output of the light receiving element, for example, a patient in which a balloon catheter is indwelled in a bladder, in which urine flows in the tube and the urine analyzing unit analyzes the urine based on the output of the light receiving element. It is possible to accurately and automatically detect the state of occult blood level and the like with respect to urine. Therefore, not only can the treatment according to the patient's condition be appropriately performed, but, for example, medical resources can be efficiently used.

As a specific embodiment of the body fluid analyzer according to the present invention, blood flows in the tube, and the blood analysis unit further analyzes the blood based on the output of the light receiving element. The thing is mentioned. For example, it becomes possible to measure the state such as hematocrit value of blood circulating in the artificial dialysis apparatus without contact during dialysis, and it becomes possible to manage the state of blood more accurately.

As described above, according to the body fluid analysis device of the present invention, by attaching the attachment to the base, the tube is sandwiched between the base and the attachment, and the space between the light emitting element and the light receiving element is The light necessary for analysis of body fluid can be in a state suitable for acquisition by the light receiving element. Therefore, since the body fluid in the tube can be accurately analyzed based on light, it is possible to automate accurate classification of the state even with an indicator that is difficult to determine, for example, the degree of blood loss.

The schematic diagram which shows the state attached with respect to the urine bag of the bodily fluid analyzer which concerns on 1st Embodiment of this invention. BRIEF DESCRIPTION OF THE DRAWINGS The typical disassembled perspective view of the bodily fluid analyzer which concerns on 1st Embodiment of this invention. BRIEF DESCRIPTION OF THE DRAWINGS The typical perspective view which shows the state which attached the attachment with respect to the base of the bodily fluid analyzer which concerns on 1st Embodiment of this invention. BRIEF DESCRIPTION OF THE DRAWINGS The typical perspective view which shows the assembled state of the bodily fluid analyzer which concerns on 1st Embodiment of this invention. Typical sectional drawing and functional block diagram of the bodily fluid analyzer which concern on 1st Embodiment of this invention. The typical disassembled perspective view of the bodily fluid analyzer which concerns on 2nd Embodiment of this invention. The schematic perspective view which shows the state which attached the attachment with respect to the base of the bodily fluid analyzer which concerns on 2nd Embodiment of this invention. The schematic perspective view which shows the assembled state of the bodily fluid analyzer which concerns on 2nd Embodiment of this invention. The schematic perspective view of the bodily fluid analyzer which concerns on 3rd Embodiment of this invention. The typical disassembled perspective view of the bodily fluid analyzer which concerns on 4th Embodiment of this invention. The schematic diagram which shows the use condition of the bodily fluid analyzer of 4th Embodiment.

100 · · · body fluid analysis device 1 · · · base 10 · · · groove 11 · · · body portion 12 · · · protruding portion 13 · · · housing portion 14 · · · housing portion bottom surface 15 · · · passing hole L · · · .. Light emitting element 2 ... Attachment 21 ... Contact surface 22 ... Surrounding side 3 ... Cover 31 ... Pressing part 32 ... Shielding part D ... Light receiving element UB ... Urine bag T1 ··· Urine tube T2 ··· Discharge tube BG · · · Reservoir

A bodily fluid analyzer 100 according to a first embodiment of the present invention will be described with reference to FIGS. 1 to 5. As shown in FIG. 1, the body fluid analysis device 100 according to the first embodiment is attached to a urine bag UB for storing urine which is inducted from a balloon catheter indwelling to a bladder of a hospitalized patient, for example, It analyzes the state of circulating urine. Here, the urine bag UB includes a urinary tube T1 connected to an end of the balloon catheter that is outside the patient's body, and a reservoir BG in which urine having passed through the urinary tube T1 is stored. And a discharge pipe T2 for discharging urine accumulated from the storage part BG to the outside. The urinary duct T1, the reservoir BG, and the discharge pipe T2 are each formed of a transparent resin having translucency, and are configured such that the urine inside can be viewed. In addition, the urinary duct T1 and the discharge pipe T2 are configured as a translucent cylindrical tube.

In the first embodiment, the body fluid analysis device 100 is attached to the urinary tract T1, and emits light to urine which is circulating in or retained in the urinary tract T1, and the transmitted light thereof For example, it is configured to automatically determine the degree of inoculum.

As shown in FIGS. 2 to 5, the body fluid analyzer 100 comprises a base 1 having a light emitting element L, a light receiving element D, and an attachment 2 attached to the base 1 and an attachment 2 attached. A cover 3 for covering the base 1 and an analyzer 5 for analyzing urine based on the output of the light receiving element D are provided. As shown in FIGS. 3 and 5, in a state where the attachment 2 is attached to the base 1, the urinary tract T1 which is a tube is sandwiched, and the light emitting element L and the light receiving element D mutually It is configured to face each other. Here, the light emitting element L is, for example, a chip-type LED, and the light receiving element D is a photodiode. In addition, the base 1 is fixed by screwing to the board BD on which the urine bag UB is hung.

As shown in FIGS. 2 and 5, the base 1 is provided with a linearly extending groove 10 which is fitted in a state where the urinary duct T1 is extended straight. Further, the base 1 has a main body portion 11 in which a housing portion 13 in which the attachment 2 is fitted and housed is formed, and two projecting portions 12 projecting to both sides in the extending direction of the groove 10 with respect to the main body portion 11 It consists of

The groove 10 passing through the main body 11 and the two protrusions 12 has a width dimension substantially the same as the outer diameter of the urinary duct T1, and a depth dimension substantially the same as the outer diameter of the urinary duct T1, Alternatively, it is slightly smaller than the outer diameter of the urinary tract T1. That is, when the urinary duct T1 is fitted to the groove 10, the outer surface of the urinary duct T1 on the opening side of the groove 10 is substantially flush with the bottom surface of the housing portion 13 or slightly outward. It is done like that.

The housing portion 13 formed on the front side of the main body portion 11 is a recess formed to be substantially the same as the external dimension of the attachment 2 as shown in FIG. It is made to fit. In the first embodiment, the height dimension of the standing wall of the housing portion 13 is set to about 1/3 of the height dimension of the attachment 2, and only the bottom surface side provided with the light receiving element D in the attachment 2 is accommodated The top surface side of the attachment 2 is disposed outside the accommodation portion 13. Further, the end face of the standing wall forming the inner wall surface of the housing portion 13 is formed to be flush with the side surface of the groove 10. That is, the standing wall forming the housing portion 13 is configured to prevent the light from the opening side from entering the central side of the main body portion 11 when viewed from the extension direction of the urinal tube T1.

Further, as shown in the cross-sectional view of FIG. 5, light emitted from the light emitting element L accommodated in the inside of the main body 11 is allowed to pass through the center of the bottom of the groove 10 formed in the main body 11. Through holes 15 are formed. A housing space 16 for housing the light emitting element L and the substrate S on which the light emitting element L and its drive circuit are mounted is formed on the bottom surface side of the base 1, and the housing space 16 is closed by the lid 17. is there. Further, the light emission surface of the light emitting element L is disposed in the accommodation space 16 so as to face the passage hole 15. For example, a wavelength of light emitted from the light emitting element L is selected to be suitable for absorption analysis, and a wavelength emitted from the light emitting element L may be a single wavelength or a plurality of wavelengths.

As shown in FIGS. 2 to 5, the attachment 2 has a substantially rectangular parallelepiped shape, and a light receiving element D is provided at the center of the bottom surface. As shown in FIG. 5, the bottom surface of the attachment 2 is the bottom surface 14 of the housing portion of the base 1 and the contact surface 21 that contacts the outer surface of the urine drainage tube T1. The light receiving surface of the light receiving element D is this contact It is flush with surface 21. Therefore, in a state in which the attachment 2 is attached to the base 1, the urinal T1 is pressed against the bottom of the groove 10 of the base 1 by the contact surface 21 and the light receiving surface of the light receiving element D. Further, the light receiving element D is in contact with the outer surface of the urinary duct T1. The attachment 2 is provided with a micro USB terminal or the like connected to a substrate to which the internal light receiving element D is attached, so that power can be supplied to the light receiving element D, an output can be obtained, etc. It is For the light receiving element D, for example, a wavelength band of light that can be received is set in accordance with the wavelength of the light emitted from the light emitting element L. Conversely, the light receiving element D may be configured to receive only a single wavelength.

The cover 3 has a shape corresponding to the base 1, and as shown in FIGS. 3 and 4, both the base 1 and the attachment 2 attached to the base 1 are attached so as to cover all from the top side Be The cover 3 covers the main body 11 of the base 1 and covers the pressing part 31 for pressing the attachment 2 against the base 1 and the projecting part 12 of the base 1, and external light is attached to the main body 11 of the base 1 And a shielding portion 32 for preventing the light receiving element D of the attachment 2 from being incident.

As shown in FIGS. 2 to 5, an engagement structure 4 is formed between the base 1 and the attachment 2, and the cover 3 is attached to the base 2 when the cover 3 is attached to the base 1. It is configured to be kept pressed against the urinary duct T1 in a pinched state. That is, the engagement structure 4 includes an engagement protrusion 41 formed on the base 1 and an engagement recess 42 formed on the cover 3, and the engagement protrusion 41 and the engagement recess 42 engage with each other to hold the base. The cover 3 is fixed to 1. In this embodiment, the engaging projections 41 and the engaging recesses 42 are respectively provided in pairs on the two outer side surfaces of the protrusion 12 and the two side surfaces of the shielding portion 32.

In the state where the cover 3 is attached to the base 1, the light receiving element D is pressed against the outer surface of the urinary duct T 1 and fixed in the groove 10 of the base 1. For this reason, the light receiving element D is disposed on the optical axis of the light emitting element L, and the light receiving element D is in contact with the outer surface of the urinary duct T1 and is suitable for receiving light necessary for analysis of urine. The state is realized. In addition, since the urinary duct T1 is sandwiched between the base 1 and the attachment 2, it is possible to prevent deviation with respect to the extension direction of the urinary duct T1, and analysis of urine at the same location in the urinary duct T1 It is possible to do

The analysis device 5 is configured to acquire the output of the light receiving element D by wire or wirelessly and to determine the latent blood level of urine. More specifically, the analysis device 5 has its function realized by a so-called computer provided with, for example, a CPU, a memory, an A / D / D / A converter, and other input / output means. The analysis device 5 executes an analysis program stored in the memory, and when various devices cooperate, as shown in FIG. 5, the analysis device 5 exhibits at least functions as the measurement unit 51 and the urine analysis unit 52.

The measuring unit 51 converts the light amount received based on the A / D converted output from the light receiving element D.

The urine analysis unit 52 calculates the hematocrit value based on the light amount obtained by the measurement unit 51, and determines the latent blood level from the hematocrit value. Specifically, for example, when the hemagtrit value is less than 0.1%, the urine analysis unit 52 determines that the level is 0 (Lv. 0) and the hemagtrit value is 0.1% or more and less than 0.5%. Level 1 (Lv. 1), hematocrit value of 0.5% or more and less than 1.0%, level 2 (Lv. 2), hematocrit value of 1.0% or more and less than 3.0% In some cases, the level 3 (Lv. 3), when the hematocrit value is 3.0% or more and less than 10.0%, the level 4 (Lv. 4), and when the hematocrit value is 10.0% or more Is determined to be level 5 (Lv. 5). The urine analysis unit 52 may determine the latent blood level constantly or at predetermined time intervals.

According to the body fluid analysis apparatus 100 configured as described above, the light emitting element L and the light receiving element D can be positioned suitable for urine measurement only by attaching them so as to be sandwiched between the base 1 and the attachment 2 with respect to the urinary tract T1. It can be positioned at

Furthermore, by inserting the urinary tract T1 between the base 1 and the attachment 2, the light receiving element D can realize a predetermined contact state with the outer surface of the urinary tract T1. For this reason, it is possible to reduce the influence of light passing through the urinary tract T1 and to realize an optical system suitable for sufficiently detecting the passed light with high reproducibility. Therefore, even when a nurse who is not familiar with the assembly of the optical system or the machine attaches the base 1 and the attachment 2 to the ureter T1, the device error hardly occurs.

In addition, the base 1 includes a main body 11 including an optical system including the light emitting element L and the light receiving element D, and two protrusions 12 bulging outward from the main body 11. Since the cover 3 is attached so as to cover both 11 and the protrusion 12, it is possible to prevent external light from entering the main body 11 from the protrusion 12. In addition, because the portion where the urinary tract T1 is exposed to outside light can be separated from the main body 11 by the projecting portion 12, for example, the light satisfies the total reflection condition in the resin that constitutes the urinary tract T1. Even when incident at an incident angle, the light can be sufficiently attenuated before reaching the main body portion 11 and substantially undetected by the light receiving element D.

From these facts, based on the light detected by the light receiving element D, it is possible to accurately analyze the occult blood level of the urine in the ureter T1 without contact. Therefore, it is possible to automate the determination of the latent blood level and the like conventionally determined by visual observation by a nurse, and to significantly reduce the burden on the medical site.

In addition to retrofitting the body fluid analyzer 100 of the first embodiment to the urine bag UB which normally does not have the role of a measuring device, it is possible not only to simply store urine but also to use the bladder of a patient, etc. Can be added as a medical device for managing the urinary system. As described above, since the body fluid analyzer 100 can be retrofitted to the urine bag UB, it is possible to use the urine bag UB without changing the various urine bags UB used in each hospital.

Next, a body fluid analyzer 100 according to a second embodiment of the present invention will be described with reference to FIGS. 6 to 8. In addition, suppose that the same code | symbol is attached | subjected to the member corresponding to the member demonstrated in 1st Embodiment.

The body fluid analyzer 100 of the second embodiment is attached to a blood transport tube T3 which is a tube through which blood dialyzed in, for example, an artificial dialysis device or blood after dialysis flows, and analyzes the state of the blood Used for

The body fluid analyzer 100 of the second embodiment has the size of the groove 10 in accordance with the outer diameter of the blood transport pipe T3 as shown in FIGS. 6 and 7 in comparison with the body fluid analyzer 100 of the first embodiment. Is different in that the housing portion 13 is configured to be able to accommodate the entire attachment 2.

In addition, the body fluid analysis apparatus 100 according to the second embodiment includes a blood analysis unit (not shown) instead of the urine analysis unit 52, and based on the output of the light receiving element D, evaluation items such as blood hematocrit value etc. It is configured to calculate.

Thus, even with the body fluid analyzer 100 of the second embodiment, the same effects as those of the first embodiment can be enjoyed in the artificial dialysis device.

Next, a body fluid analyzer 100 according to a third embodiment of the present invention will be described with reference to FIG. In addition, suppose that the same code | symbol is attached | subjected to the member corresponding to the member demonstrated in 1st Embodiment.

The body fluid analysis device 100 according to the third embodiment, as compared with the body fluid analysis device 100 according to the first embodiment, has an attachment 2 in which the cover 3 is attached to the body portion 11 and the body portion 11 as shown in FIG. It differs in that it is not provided with a pressing part that covers and presses against the base 1, and that only a shielding part 32 that covers the projecting part 12 is provided.

Even with the cover 3 configured in this manner, external light incident from the axial direction of the urinary canal T1 can be made difficult to detect by the light receiving element D, and urine analysis accuracy can be improved. Moreover, if fitting of the attachment 2 with respect to the accommodating part 13 is set to tightness, even if it does not press with the cover 3, the urinary tract T1 can be inserted enough. Further, since the urinary duct T1 is provided between the attachment 2 and the main body 11, external light can be prevented from entering from the radial direction even if the cover 3 is not provided for this part.

Next, a body fluid analyzer 100 according to a fourth embodiment of the present invention will be described with reference to FIGS. 10 and 11. FIG. In addition, suppose that the same code | symbol is attached | subjected to the member corresponding to the member demonstrated in 1st Embodiment.

Compared with the body fluid analysis device 100 according to the first embodiment, as shown in FIG. 10, in the body fluid analysis device 100 according to the fourth embodiment, the groove 10 formed in the base 1 is not straight but curved. And the engagement protrusion 41 forming the engagement structure 4 is formed on only one of the outer side surfaces of the projection 12, and the engagement recess 42 is formed on only one side of the shield 32. There are differences in The configuration of the groove 10 will be described in detail below.

The groove 10 is formed in the base 1 so as to form a substantially U-shape as shown in FIGS. 10 and 11, and the light receiving element D is guided in a use state in which the light passing through the urine is received and analyzed. The inflow side and the outflow side of the ureter T1 are disposed at positions higher than the optical axis of the light emitting element L, respectively.

That is, in the vicinity of the optical axis of the light emitting element L, the groove 10 is curved so as to have an apex. Further, as shown in FIG. 11, in the use state, the groove 10 is installed so as to be vertically downwardly convex, and urine is present in a portion of the urinary duct T1 which is sandwiched between the main body portion 11 of the base 1 and the attachment 2. It is made to stay temporarily.

Since the groove 10 is curved and provided as described above, an amount necessary to analyze the urine always exists in the vicinity of the optical axis of the light emitting element D even when the urine volume is small as in an elderly patient, for example. It will be possible to carry out urine analysis continuously. In addition, since urine can not flow at a flow velocity equal to or higher than a predetermined value in the urinary tract T1, generation of an error in the analysis result due to the influence of the flow velocity can be prevented.

Other embodiments will be described.

The body fluid analysis apparatus according to the first embodiment is attached to the ureteral tube, but is attached to, for example, the drainage tube, and analyzes information such as urine occult blood level when excreting urine. It is also good. Further, the body fluid analyzer may measure the evaluation items other than the latent blood level based on the output of the light receiving element. For example, detectable parameters may be analyzed based on transmitted light such as turbidity of urine.

In the body fluid analysis device according to each embodiment, the light emitting element is provided on the base and the light receiving element is provided on the attachment, but the light receiving element may be provided on the base and the light emitting element may be provided on the attachment. Alternatively, the light emitting element may be disposed in the through hole of the base and attached in contact with the outer surface of the tube. Furthermore, in each of the embodiments, the light emitting element or the light receiving element is provided on either one of the base or the interlocking touch element, and the light emitting element light receiving element is configured to sandwich the tube in the radial direction. A light emitting element and a light receiving element may be provided on one of the two. In such a case, for example, light emitted from the light emitting element enters the tube, passes through the body fluid, is reflected on the opposite side of the tube, and detects light returned by the light receiving element. May be That is, the light emitting element and the light receiving element may be configured as a transmission type detector that sandwiches the tube, or the light emitting element and the light receiving element may be configured as a reflection type detector disposed on the same side with respect to the outer surface of the tube. You may In addition, both of the light emitting element and the light receiving element may be provided in the base, and may be configured as a transmissive detector in which the optical axis is set in the width direction of the groove.

The base of the body fluid analyzer may be constituted only by the main body, and may not be provided with the protrusion. Also, only one protrusion may be provided to the main body.

Also, the body fluid analyzer may be configured only with the base and the attachment. In this case, an engagement structure may be configured between the base and the attachment, and light shielding is realized so that stray light does not enter the optical system including the light emitting element and the light receiving element in the state where the attachment is attached. Are preferred.

The shape of the groove is not limited to that curved in a U-shape as in the fourth embodiment, and it may be curved so that the body fluid is temporarily stored in the vicinity of the main body in the use state. For example, the inflow side of the tube may be horizontally incident, and the outflow side of the tube may be curved upward to form a groove so as to interrupt the flow of body fluid. Moreover, the groove may be formed in a V-shape.

The body fluid analyzed by the body fluid analyzer is not limited to those described in the first and second embodiments. The body fluid may be lymph fluid, interstitial fluid, spinal fluid, saliva, sweat or the like. For example, the fluid flowing through the drain taken up by the patient during or after surgery may be analyzed.

In addition, unless it is contrary to the meaning of the present invention, a part of various embodiments may be combined, and a part of each embodiment may be changed.

According to the present invention, it is possible to provide a body fluid analyzer capable of accurately classifying states based on light on body fluid in a tube, for example, even indicators which are difficult to determine for humans, such as the blood contamination degree.

Claims

A body fluid analyzer which irradiates light to body fluid in a translucent tube and analyzes the body fluid based on the light passing through the tube,
Base and
An attachment attached to the base such that the tube is nipped with respect to the radial direction with the base;
A light emitting element provided on either the base or the attachment;
A light receiving element provided on either the base or the attachment;
In a state where the attachment is attached to the base, the light emitting element and the light receiving element are disposed so as to sandwich the tube in the radial direction between the base and the attachment, or An apparatus for analyzing body fluid, wherein both the light emitting element and the light emitting element are disposed on either the base or the attachment.
The attachment comprises a contact surface that contacts the outer surface of the tube;
The body fluid analyzer according to claim 1, wherein the tube is configured to be pressed against the base in a state where the attachment is attached to the base.
The body fluid analyzer according to claim 2, wherein the attachment is configured such that at least a part of the light emitting element or the light receiving element is substantially flush with the contact surface.
The base comprises a groove in which the tube is fitted;
The bodily fluid analyzer according to claim 1, wherein a passage hole for passing light emitted from the light emitting element is formed at the bottom of the groove.
The base comprises a receptacle into which the attachment is fitted;
The bodily fluid analyzer according to claim 1, wherein the light receiving element is disposed on an optical axis of the light emitting element in a state where the attachment is fitted into the housing portion.
The base is
A main body to which the attachment is attached;
And a protruding portion that protrudes outward from the main body along the extending direction of the groove and in which a portion of the groove is formed,
The body fluid analyzer according to claim 4, further comprising a cover configured to cover at least the protrusion of the base.
An engagement structure formed between the base and the cover;
The cover is configured to cover the body portion of the base and the attachment attached to the body portion of the base;
The body fluid analyzer according to claim 4, wherein the cover is configured to press the attachment toward the base in a state in which the cover is engaged with the base by the engagement structure.
The body fluid analyzer according to claim 4, wherein the groove is formed to be curved.
The bodily fluid analyzer according to claim 8, wherein the groove is formed to be convex downward with respect to the vertical direction in a use state in which light received through the tube is received by the light receiving element.
The bodily fluid analyzer according to claim 9, wherein the groove is formed to have a vertex in the vicinity of the optical axis of the light emitting element in the main body portion.
Urine flows into the tube,
The body fluid analyzer according to claim 1, further comprising a urine analysis unit that analyzes urine based on the output of the light receiving element.
Blood flows into the tube,
The body fluid analyzer according to claim 1, further comprising a blood analyzer that analyzes blood based on the output of the light receiving element.