WO2019066752A3 - Vagus nerve stimulator with antimicrobial characteristic - Google Patents

Vagus nerve stimulator with antimicrobial characteristic Download PDF

Info

Publication number
WO2019066752A3
WO2019066752A3 PCT/TR2018/050246 TR2018050246W WO2019066752A3 WO 2019066752 A3 WO2019066752 A3 WO 2019066752A3 TR 2018050246 W TR2018050246 W TR 2018050246W WO 2019066752 A3 WO2019066752 A3 WO 2019066752A3
Authority
WO
WIPO (PCT)
Prior art keywords
vagus nerve
stimulator
nerve stimulator
region
antimicrobial characteristic
Prior art date
Application number
PCT/TR2018/050246
Other languages
French (fr)
Other versions
WO2019066752A2 (en
Inventor
Hayati DENIZ
Original Assignee
Deniz Hayati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deniz Hayati filed Critical Deniz Hayati
Publication of WO2019066752A2 publication Critical patent/WO2019066752A2/en
Publication of WO2019066752A3 publication Critical patent/WO2019066752A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36064—Epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36078—Inducing or controlling sleep or relaxation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

The present invention is a vagus nerve stimulator positioned in the region inside the body (30) and which stays in the region it is placed in a permanent manner and having stimulator components (10) which incorporate with the vagus nerve and the peripheral tissues, said vagus nerve stimulator is characterized by comprising an antimicrobial polymeric layer (20) applied by means of covalent bonds, such that no gap remains, through a holding surface (21) to the whole outer casing (11) of the stimulator components (10) which remain inside the body in a manner preventing formation of bio-film by the bacteria (40) in order to prevent infection risk in the regions inside the body (30).
PCT/TR2018/050246 2017-06-12 2018-05-17 Vagus nerve stimulator with antimicrobial characteristic WO2019066752A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2017/08610 2017-06-12
TR2017/08610A TR201708610A2 (en) 2017-06-12 2017-06-12 VAGUS NERVE STIMULATOR WITH ANTIMICROBIAL PROPERTIES

Publications (2)

Publication Number Publication Date
WO2019066752A2 WO2019066752A2 (en) 2019-04-04
WO2019066752A3 true WO2019066752A3 (en) 2019-05-16

Family

ID=65902664

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2018/050246 WO2019066752A2 (en) 2017-06-12 2018-05-17 Vagus nerve stimulator with antimicrobial characteristic

Country Status (2)

Country Link
TR (1) TR201708610A2 (en)
WO (1) WO2019066752A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186528A1 (en) * 2003-03-20 2004-09-23 Medtronic, Inc. Subcutaneous implantable medical devices with anti-microbial agents for chronic release
US20050013842A1 (en) * 2003-07-16 2005-01-20 Yongxing Qiu Antimicrobial medical devices
US20050058844A1 (en) * 2002-12-19 2005-03-17 Rubner Michael F. Method for making medical devices having antimicrobial coatings thereon
US20110021899A1 (en) * 2009-07-23 2011-01-27 Surmodics, Inc. Conductive polymer coatings

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050058844A1 (en) * 2002-12-19 2005-03-17 Rubner Michael F. Method for making medical devices having antimicrobial coatings thereon
US20040186528A1 (en) * 2003-03-20 2004-09-23 Medtronic, Inc. Subcutaneous implantable medical devices with anti-microbial agents for chronic release
US20050013842A1 (en) * 2003-07-16 2005-01-20 Yongxing Qiu Antimicrobial medical devices
US20110021899A1 (en) * 2009-07-23 2011-01-27 Surmodics, Inc. Conductive polymer coatings

Also Published As

Publication number Publication date
TR201708610A2 (en) 2017-09-21
WO2019066752A2 (en) 2019-04-04

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