WO2018193955A1 - Deglutition function testing system using 3d camera - Google Patents

Deglutition function testing system using 3d camera Download PDF

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Publication number
WO2018193955A1
WO2018193955A1 PCT/JP2018/015342 JP2018015342W WO2018193955A1 WO 2018193955 A1 WO2018193955 A1 WO 2018193955A1 JP 2018015342 W JP2018015342 W JP 2018015342W WO 2018193955 A1 WO2018193955 A1 WO 2018193955A1
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Prior art keywords
swallowing
data
dynamics
body surface
timing information
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PCT/JP2018/015342
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French (fr)
Japanese (ja)
Inventor
佐藤 秀夫
祐士 山本
洋一朗 岩下
要一 山▲崎▼
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国立大学法人 鹿児島大学
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Priority to JP2019513590A priority Critical patent/JP6952365B2/en
Publication of WO2018193955A1 publication Critical patent/WO2018193955A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb

Definitions

  • the present invention relates to a swallowing function test system using a 3D camera.
  • swallowing function a characteristic seen in the elderly is a decrease in swallowing function (hereinafter referred to as “swallowing function”). Decreased swallowing function causes aspiration and suffocation, as well as aspiration pneumonia. Therefore, diagnosing swallowing function is important for the elderly.
  • the swallowing function can be invasively performed with a C-arm fluoroscope (VF) or a swallowing endoscope (VE, for home visit). It is common to inspect.
  • VF C-arm fluoroscope
  • VE swallowing endoscope
  • body surface dynamics body surface dynamics
  • the present invention has been made in view of the above circumstances, and provides a swallowing function test system, a swallowing function analysis method, and a program that can test the swallowing function of a subject inexpensively, simply, non-invasively and accurately.
  • the purpose is to provide.
  • a swallowing function test system includes: A timing information generator for generating timing information;
  • the body surface dynamics acquisition unit that acquires the body surface dynamics data that operates along with the swallowing operation of the subject in the period when the swallowing operation is performed, including the time point when the timing information is generated in the timing information generating unit,
  • An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including the time when the timing information is generated in the timing information generation unit; Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data
  • a generator Based on the synchronization data, an analysis unit that analyzes the correlation between the body surface dynamics and internal dynamics of the subject during the swallowing operation; Is provided.
  • the analysis unit Estimating the state of swallowing function of the subject based on the body surface dynamics data obtained by imaging again the body surface dynamics during the swallowing motion in the same subject, and the synchronization data, It is good as well.
  • the analysis unit Analyzing the state of the swallowing function of the subject based on items related to the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamics data, It is good as well.
  • the synchronous data generation unit For each subject, generate the synchronization data, The analysis unit Using the synchronization data for each subject, analyze the swallowing function of the subject corresponding to the synchronization data, It is good as well.
  • the timing information generating unit generates a sound as the timing information. It is good as well.
  • the program according to the third aspect of the present invention is: Computer A timing information generator for generating timing information; A body surface dynamics acquisition unit for acquiring body surface dynamics data that operates in accordance with the swallowing motion of the subject in a period in which the swallowing motion is performed, including the time when the timing information is generated in the timing information generator; An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including a time point when the timing information is generated in the timing information generation unit; Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data Generator, Based on the synchronization data, an analysis unit that analyzes the correlation between body surface dynamics and internal dynamics of the subject during the swallowing operation, To function as.
  • the body surface dynamics and the internal dynamics of the subject during the swallowing operation are generated. Can be analyzed. For this reason, the swallowing function of the subject can be examined inexpensively, simply, noninvasively and accurately from the body surface dynamics.
  • FIG. 1 It is a schematic diagram which shows the whole environment where the swallowing function test
  • (A) And (B) is a schematic diagram which shows a mode that synchronous data are produced
  • FIG. 1 shows the entire environment in which the swallowing function test system 1 according to the present embodiment is used.
  • the swallowing function test system 1 is a system for causing a subject P to swallow a sample and testing the swallowing function.
  • the swallowing function test system 1 is communicably connected to various facilities installed in the test room 2.
  • a speaker 3 In the examination room 2, a speaker 3, a three-dimensional shape measuring device 4, and a contrast examination device 5 are installed as such facilities.
  • Speaker 3 generates a sound (buzzer) as timing information. This sound becomes a trigger when performing various operations such as the swallowing operation of the subject P. This sound is also used for generating synchronization data, as will be described later.
  • Kinect registered trademark
  • Kinect is available as such a three-dimensional shape measuring apparatus 4.
  • Kinect records the three-dimensional position coordinates of each measurement point in real time every 1/30 seconds.
  • Kinect registered trademark
  • Kinect is advantageous in that it is small, portable, low-cost, and a software program for calculating a three-dimensional shape is open sourced.
  • the three-dimensional shape measuring apparatus 4 captures three-dimensional images of the object and records surrounding sounds using a multi-array microphone.
  • the contrast examination (Video Fluorography) apparatus 5 is an X-ray imaging apparatus that captures a fluoroscopic image of the jaw portion of the subject P. As shown in FIG. 5, the imaging direction is the lateral direction of the subject P.
  • the contrast examination apparatus 5 starts imaging the jaw portion of the subject P according to an instruction from the outside, and ends imaging according to the instruction from the outside. From this imaging result, it is possible to observe the internal dynamics of the oral cavity, pharynx, and esophagus that operate with the swallowing operation when the subject P performs the swallowing operation.
  • the contrast inspection apparatus 5 captures a fluoroscopic image of the object and records surrounding sounds.
  • the swallowing function test system 1 includes a timing information generation unit 10, a body surface dynamics acquisition unit 11, an internal dynamics acquisition unit 12, a synchronization data generation unit 13, and an analysis unit 14.
  • the timing information generator 10 causes the speaker 3 to generate sound as timing information.
  • the sound to be generated is an electronic sound such as a buzzer, but is not limited to this.
  • the sound to be generated may be a human voice.
  • the body surface dynamics acquisition unit 11 acquires body surface dynamics data related to the swallowing motion of the subject P.
  • the acquired body surface dynamics data includes time points T1 and T2 when the timing information is generated by the timing information generator 10 (see, for example, FIG. 4), and is time-series data including a period during which the swallowing operation is performed. .
  • the three-dimensional shape measuring device 4 picks up the subject P, records an electronic sound, and measures the three-dimensional shape. To start. Further, when the body surface dynamics acquisition unit 11 instructs the 3D shape measurement device 4 to end the measurement, the 3D shape measurement device 4 ends the imaging of the subject P, the recording of the electronic sound, and the measurement of the 3D shape. . Video data, electronic sound data, and a measurement result of the three-dimensional shape captured by the three-dimensional shape measurement apparatus 4 are transmitted to the body surface dynamics acquisition unit 11.
  • the body surface dynamics acquisition unit 11 includes a body surface dynamics information generation unit 11A and a storage unit 11B as shown in FIG.
  • the body surface dynamics information generation unit 11A stores the video and electronic sound data received from the three-dimensional shape measurement apparatus 4 in the storage unit 11B. This data is referred to as video and electronic sound data 11C. Furthermore, the body surface dynamics information generation unit 11A generates body surface dynamics data 11D based on the received measurement result of the three-dimensional shape and stores it in the storage unit 11B.
  • the internal kinetic acquisition unit 12 acquires internal kinetic data 12D in the oral cavity, pharynx, and esophagus of the same subject P during the period in which the swallowing operation is performed.
  • the internal dynamic data 12 ⁇ / b> D includes time points T ⁇ b> 1 and T ⁇ b> 2 when an electronic sound is generated by the timing information generation unit 10, and indicates a temporal change of a fluoroscopic image obtained by moving the jaw portion of the subject P from the side. Time series data. From this data, it is possible to observe the swallowing process from the oral phase to the pharyngeal phase to the esophageal phase.
  • the acquired internal behavior data 12 ⁇ / b> D is data for a period including time points T ⁇ b> 1 and T ⁇ b> 2 when an electronic sound is generated in the timing information generation unit 10.
  • the internal dynamic acquisition unit 12 acquires the internal dynamic data 12D and simultaneously records the electronic sound data 12C.
  • the contrast inspection apparatus 5 When the internal dynamic acquisition unit 12 instructs the contrast inspection apparatus 5 to start imaging, the contrast inspection apparatus 5 starts imaging and recording of fluoroscopic imaging of the subject P, and the internal dynamic acquisition unit 12 When instructing the end of the measurement of the fluoroscopic image of the face of the examiner P, the contrast inspection device 5 ends the imaging and recording of the fluoroscopic image of the face of the examinee P.
  • the internal dynamic data 12D and the electronic sound data 12C imaged by the contrast inspection apparatus 5 are transmitted to the internal dynamic acquisition unit 12.
  • the internal dynamic data 12D and the electronic sound data 12C are stored in the internal dynamic acquisition unit 12.
  • the synchronization data generation unit 13 generates synchronization data of internal dynamics and body surface dynamics during the swallowing motion.
  • the synchronization data is performed by combining the time points T1 and T2 when the timing information is generated in the body surface dynamic data 11D and the time points T1 and T2 when the timing information is generated in the internal dynamic data 12D.
  • FIG. 8 shows an example of a screen on which body surface dynamics and internal dynamics are simultaneously displayed based on the synchronization data 7.
  • Internal dynamic data 12D is shown on the upper left of the screen, and body surface dynamic data 11D is shown on the right.
  • time series data of the inter-oral distance L which is a part of the body surface dynamic data 11D is shown at the lower side of the screen.
  • the analysis unit 14 reads the synchronization data 7 from the synchronization data generation unit 13 and analyzes it. Specifically, the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics during the swallowing operation. The analysis of the correlation is performed, for example, by analyzing the state of the swallowing function of the subject P based on the item regarding the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamic data 11D. Is called.
  • the specific part includes information regarding the inter-oral distance L. In this case, for example, the distance L between mouth corners at rest, the distance L between mouth angles before the start of swallowing, the amount of displacement of the distance L between mouth corners of the swallowing operation, the swallowing time, and the like can be set as measurement items.
  • FIG. 9 shows a hardware configuration of the swallowing function test system 1 of FIG.
  • the swallowing function test system 1 includes a control unit 31, a main storage unit 32, an external storage unit 33, an operation unit 34, a display unit 35, and a communication unit 36.
  • the main storage unit 32, the external storage unit 33, the operation unit 34, and the display unit 35 are all connected to the control unit 31 through the internal bus 30.
  • the main storage unit 32 is composed of RAM (Random-Access Memory) or the like.
  • the main storage unit 32 is loaded with a program 39 stored in the external storage unit 33.
  • the main storage unit 32 is used as a work area (temporary data storage area) of the control unit 31.
  • the external storage unit 33 includes a non-volatile memory such as a flash memory, a hard disk, a DVD-RAM (Digital Versatile Disc Random-Access Memory), a DVD-RW (Digital Versatile Disc ReWritable).
  • a program 39 to be executed by the control unit 31 is stored in advance. Further, the external storage unit 33 supplies data used when executing the program 39 to the control unit 31 in accordance with an instruction from the control unit 31, and stores the data supplied from the control unit 31.
  • the operation unit 34 includes a pointing device such as a keyboard and a mouse, and an interface device that connects the keyboard and the pointing device to the internal bus 30. Information regarding the content operated by the operator is input to the control unit 31 via the operation unit 34.
  • the communication unit 36 is a communication interface with an external device.
  • the speaker 3, the three-dimensional shape measuring device 4, and the contrast examination device 5 are connected to be communicable via the communication unit 36.
  • the body surface dynamics acquisition unit 11 includes time points T1 and T2 when electronic sounds are generated, and the body fluctuates with the swallowing motion of the subject P during the swallowing motion.
  • the internal dynamic acquisition unit 12 changes the internal dynamic data 12D of the subject P that fluctuates with the swallowing operation in the period during which the swallowing operation is performed ( Electronic sound data 12C) is acquired (step S1: dynamic acquisition step).
  • the dynamic acquisition step is performed according to the procedure shown in FIG. This procedure is performed under the control of the swallowing function test system 1.
  • the subject P is made to wait at the measurement position.
  • Shooting by the three-dimensional shape measuring apparatus 4 is started.
  • VF imaging by the contrast inspection apparatus 5 is started and a timer is started. 4).
  • a sample (for example, water) is taken in by the first electronic sound generated at time T1. 5).
  • the sample is swallowed by the second electronic sound generated at time T2. 6).
  • the subject P raises his hand, and at that point the imaging is terminated and the measurement is terminated.
  • body surface dynamic data 11D and internal dynamic data 12D are acquired.
  • the synchronization data generation unit 13 combines the timing (T1, T2) when the electronic sound is generated with the body surface dynamic data 11D and the timing (T1, T2) when the electronic sound is generated with the internal dynamic data 12D, Synchronous data 7 between the internal dynamic data 12D and the body surface dynamic data 11D during the swallowing operation is generated (step S2; synchronous data generating step).
  • the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics of the subject P during the swallowing operation based on the synchronization data 7 (step S3; analysis process).
  • FIG. 12A shows the internal dynamics obtained when a subject P1 swallows 5 ml of water
  • FIG. 12B shows the state of fluctuation of the inter-angular distance L as the body surface dynamics at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is minimized
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • Time t4 is the time when the subject P1 raised his hand.
  • FIG. 13A shows the internal dynamics acquired when another subject P2 swallows 5 ml of water
  • FIG. 13B shows how the inter-oral distance L changes at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the distance L between the mouth corners is minimized
  • the time point t5 is a time point when the subject P2 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, and then contracted to finish swallowing and then returned to the normal length.
  • FIG. 14A shows the internal dynamics obtained when another subject P1 swallows 15 ml of water
  • FIG. 14B shows how the inter-oral distance L fluctuates at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the interoral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the inter-angular distance L is minimized
  • the time point t5 is a time point when the subject P1 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
  • FIG. 15A shows the internal dynamics acquired when another subject P2 swallows 15 ml of water
  • FIG. 15B shows the fluctuation of the inter-oral distance L at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the distance L between the mouth corners is minimized
  • the time point t5 is a time point when the subject P2 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
  • the synchronization data generating unit 13 generates the synchronization data 7 for each subject P. It is desirable that the analyzing unit 14 uses the synchronization data 7 for each subject P and analyzes the swallowing function of the subject P based on the synchronization data 7.
  • the analysis unit 14 includes a storage unit 14C, and the synchronization data 7A of the subject PA, the synchronization data 7B of the subject PB, and the synchronization data 7C of the subject PC are stored in the storage unit 14C. An example is shown.
  • the analysis unit 14 is based on the body surface dynamics data 11D acquired by imaging the body surface dynamics during the swallowing motion in the subjects PA to PC, and the synchronization data 7A to 7C.
  • the state of the swallowing function of the subjects PA to PC may be estimated. It is assumed that the swallowing function test system 1 is connected to a three-dimensional shape measuring device 4 installed in a home 8 of the subject PA, PB, or PC via a communication network 9.
  • the body surface dynamics data 11D of the subject PA is acquired by the three-dimensional shape measuring apparatus 4 installed in the home 8 of the subject PA, the data is transferred to the swallowing function test system 1 via the communication network 9. Sent to.
  • the analysis unit 14 of the swallowing function test system 1 estimates the current swallowing function state of the subject PA based on the body surface dynamics data 11D of the subject PA. For example, when the variation pattern of the inter-oral distance L obtained from the received body surface dynamics data 11D and the variation pattern of the easy-to-mouth distance L stored as the synchronization data 7A become large (for example, when the swallowing time is long or intense If it fluctuates), it is estimated that there is a possibility that a dysphagia has occurred in the subject PA. If such an estimation result is obtained, a more accurate diagnosis can be performed on the subject PA. The same applies to the subjects PB and PC. If such a mechanism is constructed, home medical care can be performed, and the burden on the subject P or the like is remarkably reduced.
  • the synchronization data 7 between the body surface dynamics data 11D and the internal dynamics data 12D of the subject P during the swallowing operation is generated.
  • the state of the swallowing function of the subject P can be estimated simply by measuring the body surface dynamics of the subject P. For this reason, the swallowing function of the subject P can be examined inexpensively, simply, noninvasively and accurately.
  • the body surface dynamic data 11D and the internal dynamic data 12D are synchronized at the timing of the time points T1 and T2.
  • the data 11D and 12D may be synchronized only at the time point T2.
  • the sample swallowed by the subject P is water, but the present invention is not limited to this. Other beverages may be used.
  • the hardware configuration and software configuration of the swallowing function test system 1 are examples, and can be arbitrarily changed and modified.
  • the function of the swallowing function test system 1 is realized by sharing an OS (operating system) and an application program, or in cooperation with the OS and the application program, only the application program part is stored in a recording medium or a storage device. May be.
  • a computer program may be posted on a bulletin board (BBS, “Bulletin“ Board System ”) on a communication network, and the computer program distributed via the network.
  • the computer program may be started and executed in the same manner as other application programs under the control of the OS, so that the above-described processing may be executed.
  • the present invention can be applied to the examination of swallowing function. In particular, it can be applied when diagnosing the swallowing function in home medical care.

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Abstract

In the present invention, a body surface movement acquisition unit (11) acquires body surface movement data which includes the timing whereat timing information is generated by a timing information generation unit (10) and which operates as a result of a subject's swallowing action during a period wherein the swallowing action is performed. An internal movement acquisition unit (12) acquires internal movement data of the same subject which includes the timing whereat timing information is generated by the timing information generation unit (10) and operates as a result of the subject's swallowing action during the period wherein the swallowing action is performed. A synchronized data generation unit (13) synchronizes the timing at which the timing information was generated in the body surface movement data and the timing at which the timing information was generated in the internal movement data, and thereby generates synchronized data of the internal movement and the body surface movement during the swallowing action. An analysis unit (14) analyzes the correlation between the body surface movement and the internal movement during the swallowing action on the basis of the synchronized data.

Description

3Dカメラを用いた摂食嚥下機能検査システムSwallowing function test system using 3D camera
 本発明は、3Dカメラを用いた摂食嚥下機能検査システムに関する。 The present invention relates to a swallowing function test system using a 3D camera.
 我が国では、高齢化が進んでおり、65歳以上の高齢者の割合が総人口の30%を超え、2042年には3878万人となる見通しである。高齢者に見られる特徴として摂食嚥下機能(以下、「嚥下機能」とする)の低下がある。嚥下機能の低下は、誤嚥を引き起こし、窒息の危険性があるうえ、誤嚥性肺炎の原因ともなる。したがって、嚥下機能を診断することは高齢者にとって重要である。 In Japan, the population is aging, and the proportion of elderly people over 65 is expected to exceed 30% of the total population, reaching 38.78 million in 2042. A characteristic seen in the elderly is a decrease in swallowing function (hereinafter referred to as “swallowing function”). Decreased swallowing function causes aspiration and suffocation, as well as aspiration pneumonia. Therefore, diagnosing swallowing function is important for the elderly.
 しかしながら、嚥下機能を診断するには口腔、咽喉内の動きを把握する必要があり、例えば、Cアーム型透視装置(VF)、嚥下内視鏡(VE、往診用)で侵襲的に嚥下機能を検査するのが一般的である。一方で、体の外部の動き(体表面動態)から非侵襲に嚥下機能を診断する測定システムが開示されている(例えば、特許文献1参照)。 However, in order to diagnose the swallowing function, it is necessary to grasp the movement in the oral cavity and throat. For example, the swallowing function can be invasively performed with a C-arm fluoroscope (VF) or a swallowing endoscope (VE, for home visit). It is common to inspect. On the other hand, a measurement system for diagnosing swallowing function non-invasively from movement outside the body (body surface dynamics) has been disclosed (for example, see Patent Document 1).
特開2013-31650号公報JP 2013-31650 A
 高齢化に伴い、国民医療費が2025年には50兆円規模に達するなかで、生活の質を確保しながら、安心した医療や介護を受けたいとの理由から在宅医療を希望する患者や家族のニーズが増加している。現在では、国民の60%が自宅での療養を望んでおり、ケアマネージャの50%が医師との連携をとりにくいと感じている。在宅での生活の質を担保する上で摂食嚥下障害への対応は必須である。 With the aging of the population, the national medical expenses will reach 50 trillion yen in 2025. Patients and families who wish to receive home medical care because they want to receive reliable medical care and care while ensuring the quality of life. Needs are increasing. Currently, 60% of the citizens want home treatment, and 50% of care managers find it difficult to work with doctors. Dealing with dysphagia is indispensable to guarantee the quality of life at home.
 しかしながら、上述したようなCアーム型透視装置等は、検査機器が高価であり、使用するのに専門的技術を要する。また、このような検査機器は侵襲的であり、検査場所が限定される。また、体の外部の動き(体表面動態)と嚥下機能との相関性には未知の部分が多い。医療現場においては、嚥下機能を顔や口の動きからスクリーニングすることがあるが、これには技術の熟練が求められる。 However, the C-arm type fluoroscopic apparatus and the like as described above are expensive in inspection equipment and require specialized techniques to be used. In addition, such an inspection device is invasive, and the inspection place is limited. Moreover, there are many unknown parts in the correlation between the external movement of the body (body surface dynamics) and the swallowing function. In the medical field, the swallowing function may be screened from the movements of the face and mouth, which requires skill in the technique.
 本発明は、上記実情に鑑みてなされたものであり、被検者の嚥下機能を、安価、簡便、非侵襲的かつ的確に検査することができる嚥下機能検査システム、嚥下機能分析方法及びプログラムを提供することを目的とする。 The present invention has been made in view of the above circumstances, and provides a swallowing function test system, a swallowing function analysis method, and a program that can test the swallowing function of a subject inexpensively, simply, non-invasively and accurately. The purpose is to provide.
 上記目的を達成するために、本発明の第1の観点に係る嚥下機能検査システムは、
 タイミング情報を発生させるタイミング情報発生部と、
 前記タイミング情報発生部でタイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得する体表面動態取得部と、
 前記タイミング情報発生部でタイミング情報が発生した時点を含み、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する内部動態取得部と、
 前記体表面動態データでタイミング情報が発生した時点と、前記内部動態データでタイミング情報が発生した時点とを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成部と、
 前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析部と、
 を備える。
In order to achieve the above object, a swallowing function test system according to the first aspect of the present invention includes:
A timing information generator for generating timing information;
The body surface dynamics acquisition unit that acquires the body surface dynamics data that operates along with the swallowing operation of the subject in the period when the swallowing operation is performed, including the time point when the timing information is generated in the timing information generating unit,
An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including the time when the timing information is generated in the timing information generation unit;
Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data A generator,
Based on the synchronization data, an analysis unit that analyzes the correlation between the body surface dynamics and internal dynamics of the subject during the swallowing operation;
Is provided.
 この場合、前記分析部は、
 同一被検者における嚥下動作中の体表面動態を再度撮像して取得された体表面動態データと、前記同期データとに基づいて、被検者の嚥下機能の状態を推定する、
 こととしてもよい。
In this case, the analysis unit
Estimating the state of swallowing function of the subject based on the body surface dynamics data obtained by imaging again the body surface dynamics during the swallowing motion in the same subject, and the synchronization data,
It is good as well.
 また、前記分析部は、
 前記体表面動態データから得られる嚥下動作中の体表面上の特定の部位の動態に関する項目に基づいて、被検者の嚥下機能の状態を分析する、
 こととしてもよい。
In addition, the analysis unit
Analyzing the state of the swallowing function of the subject based on items related to the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamics data,
It is good as well.
 前記特定の部位には、口角間距離が含まれる、
 こととしてもよい。
The specific part includes a distance between mouth corners,
It is good as well.
 前記同期データ生成部は、
 被検者毎に、前記同期データを生成し、
 前記分析部は、
 被検者毎の同期データを用いて、当該同期データに対応する被検者の嚥下機能を分析する、
 こととしてもよい。
The synchronous data generation unit
For each subject, generate the synchronization data,
The analysis unit
Using the synchronization data for each subject, analyze the swallowing function of the subject corresponding to the synchronization data,
It is good as well.
 前記タイミング情報発生部は、前記タイミング情報として、音を発生させる、
 こととしてもよい。
The timing information generating unit generates a sound as the timing information.
It is good as well.
 本発明の第2の観点に係る嚥下機能分析方法は、
 タイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得すると同時に、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する動態取得工程と、
 前記体表面動態データでタイミング情報が発生したタイミングと、前記内部動態データでタイミング情報が発生したタイミングとを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成工程と、
 前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析工程と、
 を含む。
The swallowing function analysis method according to the second aspect of the present invention is:
The body surface dynamics data that operates along with the swallowing motion of the subject in the period during which the swallowing motion is performed, including the time point when the timing information is generated, and at the same time, A dynamic acquisition process for acquiring internal dynamic data of the same subject operating along with the movement;
Synchronous data for generating synchronous data of internal dynamics and body surface dynamics during the swallowing operation by combining timing when timing information is generated with the body dynamics data and timing when timing information is generated with the internal dynamic data Generation process;
An analysis step for analyzing a correlation between body surface dynamics and internal dynamics of the subject during the swallowing motion based on the synchronization data;
including.
 本発明の第3の観点に係るプログラムは、
 コンピュータを、
 タイミング情報を発生させるタイミング情報発生部、
 前記タイミング情報発生部でタイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得する体表面動態取得部、
 前記タイミング情報発生部でタイミング情報が発生した時点を含み、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する内部動態取得部、
 前記体表面動態データでタイミング情報が発生した時点と、前記内部動態データでタイミング情報が発生した時点とを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成部、
 前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析部、
 として機能させる。
The program according to the third aspect of the present invention is:
Computer
A timing information generator for generating timing information;
A body surface dynamics acquisition unit for acquiring body surface dynamics data that operates in accordance with the swallowing motion of the subject in a period in which the swallowing motion is performed, including the time when the timing information is generated in the timing information generator;
An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including a time point when the timing information is generated in the timing information generation unit;
Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data Generator,
Based on the synchronization data, an analysis unit that analyzes the correlation between body surface dynamics and internal dynamics of the subject during the swallowing operation,
To function as.
 本発明によれば、嚥下動作中の被検者の体表面動態データと内部動態データとのタイミングを合わせた同期データを生成するので、嚥下動作中の被検者の体表面動態と内部動態との相関性を分析することができる。このため、体表面動態から、被検者の嚥下機能を、安価、簡便、非侵襲的かつ的確に検査することができる。 According to the present invention, since the synchronization data that matches the timing of the body surface dynamics data and the internal dynamics data of the subject during the swallowing operation is generated, the body surface dynamics and the internal dynamics of the subject during the swallowing operation are generated. Can be analyzed. For this reason, the swallowing function of the subject can be examined inexpensively, simply, noninvasively and accurately from the body surface dynamics.
本発明の実施の形態に係る嚥下機能検査システムが用いられる全体環境を示す模式図である。It is a schematic diagram which shows the whole environment where the swallowing function test | inspection system which concerns on embodiment of this invention is used. 3次元形状計測装置で撮像される被検者の上半身の一例を示す図である。It is a figure which shows an example of the upper half of the subject imaged with a three-dimensional shape measuring apparatus. 3次元形状計測装置で計測される被検者の顔部の体表面動態の一例を示す図である。It is a figure which shows an example of the body surface dynamics of the face part of a subject measured with a three-dimensional shape measuring apparatus. 嚥下機能検査システムを構成する体表面動態取得部の内部構成を示すブロック図である。It is a block diagram which shows the internal structure of the body surface dynamics acquisition part which comprises a swallowing function test | inspection system. 体表面動態データの一例を示す図である。It is a figure which shows an example of body surface dynamics data. 透視画像の一例を示す図である。It is a figure which shows an example of a fluoroscopic image. 内部動態データの一例を示す図である。It is a figure which shows an example of internal dynamics data. (A)及び(B)は、同期データを生成する様子を示す模式図である。(A) And (B) is a schematic diagram which shows a mode that synchronous data are produced | generated. 同期データを表示した場合の画面の一例を示す図である。It is a figure which shows an example of the screen at the time of displaying synchronous data. 嚥下機能検査システムのハードウエア構成を示すブロック図である。It is a block diagram which shows the hardware constitutions of a swallowing function test | inspection system. 本発明の実施の形態に係る嚥下機能解析方法のフローチャートである。It is a flowchart of the swallowing function analysis method which concerns on embodiment of this invention. 動態を取得する手順のタイミングチャートである。It is a timing chart of the procedure which acquires dynamics. 内部動態データの具体例(その1)である。It is a specific example (the 1) of internal dynamics data. 体表面動態データとの特定の部位の変動パターンの一例(その1)である。It is an example (the 1) of the fluctuation pattern of the specific site | part with body surface dynamics data. 内部動態データの具体例(その2)である。It is a specific example (the 2) of internal dynamics data. 体表面動態データとの特定の部位の変動パターンの一例(その2)である。It is an example (the 2) of the fluctuation pattern of the specific site | part with body surface dynamics data. 内部動態データの具体例(その3)である。It is a specific example (the 3) of internal dynamics data. 体表面動態データとの特定の部位の変動パターンの一例(その3)である。It is an example (the 3) of the fluctuation pattern of the specific site | part with body surface dynamics data. 内部動態データの具体例(その4)である。It is a specific example (the 4) of internal dynamics data. 体表面動態データとの特定の部位の変動パターンの一例(その4)である。It is an example (the 4) of the fluctuation pattern of the specific site | part with body surface dynamics data. 複数の被検者に対して現在の嚥下機能の検査を行うためのシステムのブロック図である。It is a block diagram of a system for examining a present swallowing function for a plurality of subjects.
 以下、本発明の実施の形態について図面を参照して詳細に説明する。 Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
 図1には、本実施の形態に係る嚥下機能検査システム1が用いられる全体環境が示されている。図1に示すように、嚥下機能検査システム1は、被検者Pに試料を嚥下させ、その嚥下機能を検査するシステムである。嚥下機能検査システム1は、検査室2に設置された各種設備と通信可能に接続されている。検査室2には、そのような設備として、スピーカ3と、3次元形状計測装置4と、造影検査装置5と、が設置されている。 FIG. 1 shows the entire environment in which the swallowing function test system 1 according to the present embodiment is used. As shown in FIG. 1, the swallowing function test system 1 is a system for causing a subject P to swallow a sample and testing the swallowing function. The swallowing function test system 1 is communicably connected to various facilities installed in the test room 2. In the examination room 2, a speaker 3, a three-dimensional shape measuring device 4, and a contrast examination device 5 are installed as such facilities.
 スピーカ3は、タイミング情報として音(ブザー)を発生させる。この音は、被検者Pの嚥下動作等の各種動作を行う場合のトリガーとなる。また、この音は、後述するように、同期データの生成にも用いられる。 Speaker 3 generates a sound (buzzer) as timing information. This sound becomes a trigger when performing various operations such as the swallowing operation of the subject P. This sound is also used for generating synchronization data, as will be described later.
 3次元形状計測装置4は、RGBカメラ、深度センサを用いて、被検者Pの顔部及びその周辺(例えば図2A参照)を撮像し、撮像された被検者Pの顔部及びその周辺の3次元形状(例えば図2Bに示す格子データ6)を計測する。3次元形状計測装置4は、被検者Pの上半身に設定された複数の特徴点(ノード)の装置との間の距離を測定することによって、被検者Pの顔部の体表面動態(皮膚や表層筋の動き)を計測する。すなわち、3次元形状計測装置4は、非接触型のマーカレスモーションキャプチャシステムである。 The three-dimensional shape measurement apparatus 4 uses an RGB camera and a depth sensor to image the face portion of the subject P and the periphery thereof (see, for example, FIG. 2A), and the captured face portion of the subject P and the vicinity thereof Is measured (for example, lattice data 6 shown in FIG. 2B). The three-dimensional shape measuring device 4 measures the distance between the device of a plurality of feature points (nodes) set on the upper half of the subject P, and thereby the body surface dynamics of the face of the subject P ( Measure skin and surface muscle movement). That is, the three-dimensional shape measuring apparatus 4 is a non-contact type markerless motion capture system.
 このような3次元形状計測装置4としては、例えばKinect(登録商標)がある。Kinect(登録商標)は、各計測点の3次元位置座標を、1/30秒ごとにリアルタイムに記録する。Kinect(登録商標)は、小型で持ち運び可能であり、低コストであり、3次元形状を算出するためのソフトウエアプログラムがオープンソース化されているという利点がある。3次元形状計測装置4は、対象物の3次元を撮像するとともに、マルチアレイマイクロフォンを用いて、周囲の音を録音する。 For example, Kinect (registered trademark) is available as such a three-dimensional shape measuring apparatus 4. Kinect (registered trademark) records the three-dimensional position coordinates of each measurement point in real time every 1/30 seconds. Kinect (registered trademark) is advantageous in that it is small, portable, low-cost, and a software program for calculating a three-dimensional shape is open sourced. The three-dimensional shape measuring apparatus 4 captures three-dimensional images of the object and records surrounding sounds using a multi-array microphone.
 造影検査(Video Fluorography)装置5は、被検者Pの顎部分の透視画像を撮像するX線撮像装置である。図5に示すように、撮像方向は、被検者Pの横方向となっている。造影検査装置5は、外部からの指示に従って被検者Pの顎部分の撮像を開始し、外部からの指示に従って撮像を終了する。この撮像結果により、被検者Pが嚥下動作を行う際の、嚥下動作に伴って動作する口腔、咽頭、食道の内部動態を観察することができる。造影検査装置5は、対象物の透視画像を撮像するとともに、周囲の音を録音する。 The contrast examination (Video Fluorography) apparatus 5 is an X-ray imaging apparatus that captures a fluoroscopic image of the jaw portion of the subject P. As shown in FIG. 5, the imaging direction is the lateral direction of the subject P. The contrast examination apparatus 5 starts imaging the jaw portion of the subject P according to an instruction from the outside, and ends imaging according to the instruction from the outside. From this imaging result, it is possible to observe the internal dynamics of the oral cavity, pharynx, and esophagus that operate with the swallowing operation when the subject P performs the swallowing operation. The contrast inspection apparatus 5 captures a fluoroscopic image of the object and records surrounding sounds.
 図1に戻り、嚥下機能検査システム1は、タイミング情報発生部10と、体表面動態取得部11と、内部動態取得部12と、同期データ生成部13と、分析部14と、を備える。 Referring back to FIG. 1, the swallowing function test system 1 includes a timing information generation unit 10, a body surface dynamics acquisition unit 11, an internal dynamics acquisition unit 12, a synchronization data generation unit 13, and an analysis unit 14.
 タイミング情報発生部10は、スピーカ3にタイミング情報として音を発生させる。本実施の形態では、発生させる音を、ブザーのような電子音とするが、これには限定されない。例えば、発生させる音を、人の音声としてもよい。 The timing information generator 10 causes the speaker 3 to generate sound as timing information. In the present embodiment, the sound to be generated is an electronic sound such as a buzzer, but is not limited to this. For example, the sound to be generated may be a human voice.
 体表面動態取得部11は、被検者Pの嚥下動作に関連する体表面動態データを取得する。取得される体表面動態データは、タイミング情報発生部10でタイミング情報が発生した時点T1,T2を含んでおり(例えば、図4参照)、嚥下動作が行われた期間を含む時系列データである。 The body surface dynamics acquisition unit 11 acquires body surface dynamics data related to the swallowing motion of the subject P. The acquired body surface dynamics data includes time points T1 and T2 when the timing information is generated by the timing information generator 10 (see, for example, FIG. 4), and is time-series data including a period during which the swallowing operation is performed. .
 より詳細には、体表面動態取得部11が3次元形状計測装置4に計測の開始を指示すると、3次元形状計測装置4が被検者Pの撮像及び電子音の録音及び3次元形状の計測を開始する。また、体表面動態取得部11が3次元形状計測装置4に計測の終了を指示すると、3次元形状計測装置4が被検者Pの撮像及び電子音の録音及び3次元形状の計測を終了する。3次元形状計測装置4で撮像された映像データ、電子音データ及び3次元形状の計測結果は、体表面動態取得部11に送信される。 More specifically, when the body surface dynamics acquisition unit 11 instructs the three-dimensional shape measuring device 4 to start measurement, the three-dimensional shape measuring device 4 picks up the subject P, records an electronic sound, and measures the three-dimensional shape. To start. Further, when the body surface dynamics acquisition unit 11 instructs the 3D shape measurement device 4 to end the measurement, the 3D shape measurement device 4 ends the imaging of the subject P, the recording of the electronic sound, and the measurement of the 3D shape. . Video data, electronic sound data, and a measurement result of the three-dimensional shape captured by the three-dimensional shape measurement apparatus 4 are transmitted to the body surface dynamics acquisition unit 11.
 体表面動態取得部11は、図3に示すように、体表面動態情報生成部11Aと記憶部11Bと、を備えている。体表面動態情報生成部11Aは、3次元形状計測装置4から受信した映像及び電子音データを、記憶部11Bに記憶する。このデータを、映像及び電子音データ11Cとする。さらに、体表面動態情報生成部11Aは、受信した3次元形状の計測結果に基づいて、体表面動態データ11Dを生成して、記憶部11Bに記憶する。 The body surface dynamics acquisition unit 11 includes a body surface dynamics information generation unit 11A and a storage unit 11B as shown in FIG. The body surface dynamics information generation unit 11A stores the video and electronic sound data received from the three-dimensional shape measurement apparatus 4 in the storage unit 11B. This data is referred to as video and electronic sound data 11C. Furthermore, the body surface dynamics information generation unit 11A generates body surface dynamics data 11D based on the received measurement result of the three-dimensional shape and stores it in the storage unit 11B.
 体表面動態データ11Dとしては、様々なデータを含めることができる。例えば、図2Bに示すように、特定の計測部位を口角間距離Lと設定した場合には、体表面動態情報生成部11Aは、口角間距離Lの時間変化を示す時系列データを生成して、体表面動態データ11Dに含めて記憶する。図4には、体表面動態としての口角間距離Lの時系列データ(体表面動態データ11D)と、電子音の時系列データ(映像及び電子音データ11C)とが示されている。電子音の時系列データでは、インパルス状のピークが、電子音が発生したタイミング(時点T1,T2)を示している。 Various data can be included as the body surface dynamics data 11D. For example, as shown in FIG. 2B, when the specific measurement site is set as the inter-angular distance L, the body surface dynamics information generating unit 11A generates time-series data indicating the time change of the inter-angular distance L. And stored in the body surface dynamics data 11D. FIG. 4 shows time-series data (body surface dynamic data 11D) of the inter-oral distance L as body surface dynamics and electronic sound time-series data (video and electronic sound data 11C). In the time series data of the electronic sound, the impulse-like peak indicates the timing (time point T1, T2) when the electronic sound is generated.
 図1に戻り、内部動態取得部12は、嚥下動作が行われた期間における同一被検者Pの口腔、咽頭、食道内の内部動態データ12Dを取得する。図6に示すように、内部動態データ12Dは、タイミング情報発生部10で電子音が発生した時点T1,T2を含み、被検者Pの顎部分を横から移した透視画像の時間変化を示す時系列データである。このデータを見れば、口腔相から咽頭相を経て食道相に至るまでの嚥下の過程を観察することができる。取得される内部動態データ12Dは、タイミング情報発生部10で電子音が発生した時点T1,T2を含む期間のデータである。内部動態取得部12は、内部動態データ12Dを取得すると同時に、電子音データ12Cを録音する。 Referring back to FIG. 1, the internal kinetic acquisition unit 12 acquires internal kinetic data 12D in the oral cavity, pharynx, and esophagus of the same subject P during the period in which the swallowing operation is performed. As shown in FIG. 6, the internal dynamic data 12 </ b> D includes time points T <b> 1 and T <b> 2 when an electronic sound is generated by the timing information generation unit 10, and indicates a temporal change of a fluoroscopic image obtained by moving the jaw portion of the subject P from the side. Time series data. From this data, it is possible to observe the swallowing process from the oral phase to the pharyngeal phase to the esophageal phase. The acquired internal behavior data 12 </ b> D is data for a period including time points T <b> 1 and T <b> 2 when an electronic sound is generated in the timing information generation unit 10. The internal dynamic acquisition unit 12 acquires the internal dynamic data 12D and simultaneously records the electronic sound data 12C.
 内部動態取得部12が造影検査装置5に撮像の開始を指示すると、造影検査装置5が被検者Pの透視撮像の撮像及び録音を開始し、内部動態取得部12が造影検査装置5に被検者Pの顔部の透視画像の計測の終了を指示すると、造影検査装置5が被検者Pの顔部の透視画像の撮像及び録音を終了する。造影検査装置5で撮像された内部動態データ12D及び電子音データ12Cは、内部動態取得部12に送信される。内部動態データ12D及び電子音データ12Cは、内部動態取得部12に記憶される。 When the internal dynamic acquisition unit 12 instructs the contrast inspection apparatus 5 to start imaging, the contrast inspection apparatus 5 starts imaging and recording of fluoroscopic imaging of the subject P, and the internal dynamic acquisition unit 12 When instructing the end of the measurement of the fluoroscopic image of the face of the examiner P, the contrast inspection device 5 ends the imaging and recording of the fluoroscopic image of the face of the examinee P. The internal dynamic data 12D and the electronic sound data 12C imaged by the contrast inspection apparatus 5 are transmitted to the internal dynamic acquisition unit 12. The internal dynamic data 12D and the electronic sound data 12C are stored in the internal dynamic acquisition unit 12.
 図1に戻り、同期データ生成部13は、嚥下動作中における内部動態と体表面動態との同期データを生成する。同期データは、体表面動態データ11Dでタイミング情報が発生した時点T1,T2と、内部動態データ12Dでタイミング情報が発生した時点T1,T2とを合わせることにより、行われる。 Referring back to FIG. 1, the synchronization data generation unit 13 generates synchronization data of internal dynamics and body surface dynamics during the swallowing motion. The synchronization data is performed by combining the time points T1 and T2 when the timing information is generated in the body surface dynamic data 11D and the time points T1 and T2 when the timing information is generated in the internal dynamic data 12D.
 具体的には、同期データ生成部13は、図7(A)に示すように、内部動態データ12Dに関連付けられた電子音データ12Cにおけるタイミング情報が発生した時点と、体表面動態データ(口角間距離L)11Dに関連付けられた映像音及び電子音データ11Cにおけるタイミング情報が発生した時点と、を合わせる。そして、同期データ生成部13は、図7(B)に示すように、両時点T1,T2を合わせた状態で、内部動態データ12Dと体表面動態データ11Dとを合成したデータを同期データ7として生成する。 Specifically, as shown in FIG. 7 (A), the synchronization data generation unit 13 generates the timing information in the electronic sound data 12C associated with the internal dynamic data 12D and the body surface dynamic data (between the corners of the mouth). Distance L) The video sound associated with 11D and the timing when the timing information in the electronic sound data 11C is generated are matched. Then, as shown in FIG. 7 (B), the synchronization data generation unit 13 sets the data obtained by synthesizing the internal dynamic data 12D and the body surface dynamic data 11D as the synchronous data 7 in a state where both time points T1 and T2 are combined. Generate.
 図8には、同期データ7に基づいて体表面動態と内部動態とが同時に表示された画面の一例が示されている。この画面左上には、内部動態データ12Dが示され、その右隣りには、体表面動態データ11Dが示されている。また、画面の下側には、体表面動態データ11Dの一部である口角間距離Lの時系列データが示されている。 FIG. 8 shows an example of a screen on which body surface dynamics and internal dynamics are simultaneously displayed based on the synchronization data 7. Internal dynamic data 12D is shown on the upper left of the screen, and body surface dynamic data 11D is shown on the right. In addition, time series data of the inter-oral distance L which is a part of the body surface dynamic data 11D is shown at the lower side of the screen.
 図1に戻り、分析部14は、同期データ生成部13から同期データ7を読み込んで解析する。具体的には、分析部14は、嚥下動作中における体表面動態と内部動態との相関性を分析する。相関性の分析は、例えば、体表面動態データ11Dから得られる嚥下動作中の体表面上の特定の部位の動態に関する項目に基づいて、被検者Pの嚥下機能の状態を分析することにより行われる。特定の部位には、口角間距離Lに関する情報が含まれる。この場合、例えば、安静時の口角間距離L、嚥下開始前の口角間距離L、嚥下動作の口角間距離Lの変位量、嚥下時間などを計測項目とすることができる。 1, the analysis unit 14 reads the synchronization data 7 from the synchronization data generation unit 13 and analyzes it. Specifically, the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics during the swallowing operation. The analysis of the correlation is performed, for example, by analyzing the state of the swallowing function of the subject P based on the item regarding the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamic data 11D. Is called. The specific part includes information regarding the inter-oral distance L. In this case, for example, the distance L between mouth corners at rest, the distance L between mouth angles before the start of swallowing, the amount of displacement of the distance L between mouth corners of the swallowing operation, the swallowing time, and the like can be set as measurement items.
 図9は、図1の嚥下機能検査システム1のハードウエア構成を示す。図9に示すように、嚥下機能検査システム1は、制御部31、主記憶部32、外部記憶部33、操作部34、表示部35及び通信部36を備える。主記憶部32、外部記憶部33、操作部34、表示部35はいずれも内部バス30を介して制御部31に接続されている。 FIG. 9 shows a hardware configuration of the swallowing function test system 1 of FIG. As shown in FIG. 9, the swallowing function test system 1 includes a control unit 31, a main storage unit 32, an external storage unit 33, an operation unit 34, a display unit 35, and a communication unit 36. The main storage unit 32, the external storage unit 33, the operation unit 34, and the display unit 35 are all connected to the control unit 31 through the internal bus 30.
 制御部31は、CPU(Central Processing Unit)等から構成されている。このCPUが、外部記憶部33に記憶されているプログラム39を実行することにより、図1に示す嚥下機能検査システム1の各構成要素が実現される。制御部31は、タイマを有している。 The control unit 31 includes a CPU (Central Processing Unit) and the like. The CPU executes the program 39 stored in the external storage unit 33, thereby realizing each component of the swallowing function test system 1 shown in FIG. The control unit 31 has a timer.
 主記憶部32は、RAM(Random-Access Memory)等から構成されている。主記憶部32には、外部記憶部33に記憶されているプログラム39がロードされる。この他、主記憶部32は、制御部31の作業領域(データの一時記憶領域)として用いられる。 The main storage unit 32 is composed of RAM (Random-Access Memory) or the like. The main storage unit 32 is loaded with a program 39 stored in the external storage unit 33. In addition, the main storage unit 32 is used as a work area (temporary data storage area) of the control unit 31.
 外部記憶部33は、フラッシュメモリ、ハードディスク、DVD-RAM(Digital Versatile Disc Random-Access Memory)、DVD-RW(Digital Versatile Disc ReWritable)等の不揮発性メモリから構成される。外部記憶部33には、制御部31に実行させるためのプログラム39があらかじめ記憶されている。また、外部記憶部33は、制御部31の指示に従って、このプログラム39の実行の際に用いられるデータを制御部31に供給し、制御部31から供給されたデータを記憶する。 The external storage unit 33 includes a non-volatile memory such as a flash memory, a hard disk, a DVD-RAM (Digital Versatile Disc Random-Access Memory), a DVD-RW (Digital Versatile Disc ReWritable). In the external storage unit 33, a program 39 to be executed by the control unit 31 is stored in advance. Further, the external storage unit 33 supplies data used when executing the program 39 to the control unit 31 in accordance with an instruction from the control unit 31, and stores the data supplied from the control unit 31.
 操作部34は、キーボード及びマウスなどのポインティングデバイス等と、キーボード及びポインティングデバイス等を内部バス30に接続するインターフェイス装置から構成されている。操作部34を介して、操作者が操作した内容に関する情報が制御部31に入力される。 The operation unit 34 includes a pointing device such as a keyboard and a mouse, and an interface device that connects the keyboard and the pointing device to the internal bus 30. Information regarding the content operated by the operator is input to the control unit 31 via the operation unit 34.
 表示部35は、CRT(Cathode Ray Tube)、LCD(Liquid Crystal Display)又は有機EL(ElectroLuminescence)などから構成される。操作者が操作情報を入力する場合は、表示部35には、操作用の画面が表示される。 The display unit 35 includes a CRT (Cathode Ray Tube), an LCD (Liquid Crystal Display), an organic EL (ElectroLuminescence), or the like. When the operator inputs operation information, an operation screen is displayed on the display unit 35.
 通信部36は、外部機器との通信インターフェイスである。例えば、通信部36を介して、スピーカ3、3次元形状計測装置4及び造影検査装置5と通信可能に接続される。 The communication unit 36 is a communication interface with an external device. For example, the speaker 3, the three-dimensional shape measuring device 4, and the contrast examination device 5 are connected to be communicable via the communication unit 36.
 なお、制御部31のプログラム39の実行により、図1に示す嚥下機能検査システム1の構成において、タイミング情報発生部10、体表面動態取得部11、内部動態取得部12、同期データ生成部13及び分析部14の機能は、制御部31、主記憶部32、外部記憶部33、操作部34、表示部35及び通信部36がプログラム39の実行に従って動作することによって実現される。 In the configuration of the swallowing function test system 1 shown in FIG. 1 by executing the program 39 of the control unit 31, the timing information generating unit 10, the body surface dynamics acquiring unit 11, the internal dynamics acquiring unit 12, the synchronous data generating unit 13, and The function of the analysis unit 14 is realized by the control unit 31, the main storage unit 32, the external storage unit 33, the operation unit 34, the display unit 35, and the communication unit 36 operating according to the execution of the program 39.
 次に、嚥下機能検査システム1の動作について説明する。図10には、嚥下機能検査システム1で実行される処理(プログラム39の実行手順)、すなわち嚥下機能分析方法のフローチャートが示されている。 Next, the operation of the swallowing function test system 1 will be described. FIG. 10 shows a flowchart of a process (execution procedure of the program 39) executed by the swallowing function test system 1, that is, a swallowing function analysis method.
 図10に示すように、まず、体表面動態取得部11は、電子音が発生した時点T1,T2を含み、嚥下動作が行われた期間における被検者Pの嚥下動作に伴って変動する体表面動態データ11D(映像音及び電子音データ11C)を取得すると同時に、内部動態取得部12が、嚥下動作が行われた期間における嚥下動作に伴って変動する被検者Pの内部動態データ12D(電子音データ12C)を取得する(ステップS1;動態取得工程)。 As shown in FIG. 10, first, the body surface dynamics acquisition unit 11 includes time points T1 and T2 when electronic sounds are generated, and the body fluctuates with the swallowing motion of the subject P during the swallowing motion. At the same time that the surface dynamic data 11D (video and electronic sound data 11C) is acquired, the internal dynamic acquisition unit 12 changes the internal dynamic data 12D of the subject P that fluctuates with the swallowing operation in the period during which the swallowing operation is performed ( Electronic sound data 12C) is acquired (step S1: dynamic acquisition step).
 ここで、動態取得工程は図11に示すような手順で行われる。この手順は、嚥下機能検査システム1の制御の下で行われる。
1.被検者Pを計測位置にて待機させる。
2.3次元形状計測装置4による撮影を開始する。
3.造影検査装置5によるVF撮影を開始しタイマをスタートさせる。
4.時点T1で発生する1度目の電子音で試料(例えば、水)を取り込む。
5.時点T2で発生する2度目の電子音で試料の嚥下を行う。
6.嚥下終了時点で、被検者Pが挙手し、その時点で撮影を終了し、計測を終了する。この工程により、体表面動態データ11D及び内部動態データ12Dが取得される。
Here, the dynamic acquisition step is performed according to the procedure shown in FIG. This procedure is performed under the control of the swallowing function test system 1.
1. The subject P is made to wait at the measurement position.
2. Shooting by the three-dimensional shape measuring apparatus 4 is started.
3. VF imaging by the contrast inspection apparatus 5 is started and a timer is started.
4). A sample (for example, water) is taken in by the first electronic sound generated at time T1.
5). The sample is swallowed by the second electronic sound generated at time T2.
6). At the end of swallowing, the subject P raises his hand, and at that point the imaging is terminated and the measurement is terminated. By this step, body surface dynamic data 11D and internal dynamic data 12D are acquired.
 次に、同期データ生成部13は、体表面動態データ11Dで電子音が発生したタイミング(T1,T2)と、内部動態データ12Dで電子音が発生したタイミング(T1,T2)とを合わせて、嚥下動作中における内部動態データ12Dと体表面動態データ11Dとの同期データ7を生成する(ステップS2;同期データ生成工程)。 Next, the synchronization data generation unit 13 combines the timing (T1, T2) when the electronic sound is generated with the body surface dynamic data 11D and the timing (T1, T2) when the electronic sound is generated with the internal dynamic data 12D, Synchronous data 7 between the internal dynamic data 12D and the body surface dynamic data 11D during the swallowing operation is generated (step S2; synchronous data generating step).
 次に、分析部14は、同期データ7に基づいて、嚥下動作中の被検者Pの体表面動態と内部動態との相関性を分析する(ステップS3;分析工程)。 Next, the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics of the subject P during the swallowing operation based on the synchronization data 7 (step S3; analysis process).
 図12Aには、ある被検者P1が水を5ml嚥下した時に取得された内部動態が示され、図12Bには、その時の体表面動態としての口角間距離Lの変動の様子が示されている。図12Bでは、時点t1が嚥下指示直後の時点であり、時点t2は、口角間距離Lが最小となった時点であり、時点t3は、水が第4頚椎を通過し、嚥下終了した時点である。時点t4は、被検者P1が挙手した時点である。図12Bに示すように、この条件では、口角間距離Lは、嚥下指示直後から収縮し、その後延伸しつつ嚥下が終了した後に、通常の長さに戻った。 FIG. 12A shows the internal dynamics obtained when a subject P1 swallows 5 ml of water, and FIG. 12B shows the state of fluctuation of the inter-angular distance L as the body surface dynamics at that time. Yes. In FIG. 12B, the time point t1 is a time point immediately after the swallowing instruction, the time point t2 is the time point when the inter-oral distance L is minimized, and the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there. Time t4 is the time when the subject P1 raised his hand. As shown in FIG. 12B, under this condition, the inter-oral distance L contracted immediately after the swallowing instruction, and then returned to the normal length after the swallowing ended while extending.
 図13Aには、他の被検者P2が水を5ml嚥下した時に取得された内部動態が示され、図13Bには、その時の口角間距離Lの変動の様子が示されている。図13Bでは、時点t1が嚥下指示直後の時点であり、時点t2は、口角間距離Lが最大となった時点であり、時点t3は、水が第4頚椎を通過し、嚥下終了した時点である。また、時点t4は、口角間距離Lが最小となった時点であり、時点t5は、被検者P2が挙手した時点である。図13Bに示すように、この条件では、口角間距離Lは、嚥下指示直後から延伸し、その後収縮して嚥下が終了した後に、通常の長さに戻った。 FIG. 13A shows the internal dynamics acquired when another subject P2 swallows 5 ml of water, and FIG. 13B shows how the inter-oral distance L changes at that time. In FIG. 13B, the time point t1 is a time point immediately after the swallowing instruction, the time point t2 is the time point when the inter-oral distance L is maximum, and the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there. Further, the time point t4 is a time point when the distance L between the mouth corners is minimized, and the time point t5 is a time point when the subject P2 raises his hand. As shown in FIG. 13B, under this condition, the inter-oral distance L was stretched immediately after the swallowing instruction, and then contracted to finish swallowing and then returned to the normal length.
 このように、被検者Pが異なれば、嚥下動作に伴う口角間距離Lの変動パターンも異なるようになることが確認された。この変動パターンは、大きく2つに分かれた。これは、主として、水を前方に保持する被検者P2(図13A参照)と、水を後方に保持する被検者P1(図12A参照)とに分かれたためであると考えられる。 Thus, it was confirmed that when the subject P is different, the variation pattern of the inter-oral distance L accompanying the swallowing motion is also different. This variation pattern was roughly divided into two. This is considered to be mainly because the subject P2 (see FIG. 13A) holding water forward and the subject P1 (see FIG. 12A) holding water backward are separated.
 図14Aには、他の被検者P1が水を15ml嚥下した時に取得された内部動態が示され、図14Bには、その時の口角間距離Lの変動の様子が示されている。図14Bでは、時点t1が嚥下指示直後の時点であり、時点t2は、口角間距離Lが最大となった時点であり、時点t3は、水が第4頚椎を通過し、嚥下終了した時点である。また、時点t4は、口角間距離Lが最小となった時点であり、時点t5は、被検者P1が挙手した時点である。図14Bに示すように、この条件では、口角間距離Lは嚥下指示直後から延伸し、その後収縮して嚥下が終了した後、通常の長さに戻った。 FIG. 14A shows the internal dynamics obtained when another subject P1 swallows 15 ml of water, and FIG. 14B shows how the inter-oral distance L fluctuates at that time. In FIG. 14B, the time point t1 is a time point immediately after the swallowing instruction, the time point t2 is the time point when the interoral distance L is maximum, and the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there. Further, the time point t4 is a time point when the inter-angular distance L is minimized, and the time point t5 is a time point when the subject P1 raises his hand. As shown in FIG. 14B, under this condition, the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
 図15Aには、他の被検者P2が水を15ml嚥下した時に取得された内部動態が示され、図15Bには、その時の口角間距離Lの変動の様子が示されている。図15Bでは、時点t1が嚥下指示直後の時点であり、時点t2は、口角間距離Lが最大となった時点であり、時点t3は、水が第4頚椎を通過し、嚥下終了した時点である。また、時点t4は、口角間距離Lが最小となった時点であり、時点t5は、被検者P2が挙手した時点である。図15Bに示すように、この条件では、口角間距離Lは嚥下指示直後から延伸し、その後収縮して嚥下が終了した後、通常の長さに戻った。 FIG. 15A shows the internal dynamics acquired when another subject P2 swallows 15 ml of water, and FIG. 15B shows the fluctuation of the inter-oral distance L at that time. In FIG. 15B, the time point t1 is a time point immediately after the swallowing instruction, the time point t2 is the time point when the inter-oral distance L is maximum, and the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there. Further, the time point t4 is a time point when the distance L between the mouth corners is minimized, and the time point t5 is a time point when the subject P2 raises his hand. As shown in FIG. 15B, under this condition, the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
 このように、保持する試料(水)が多い場合、口腔全体で試料(水)を保持する傾向があることが確認された。これまでのデータを総合すると、嚥下動作中の口角間距離Lは、一般的には、嚥下指示の後、しばらくすると最大となり、その後減少する中で試料が第4頚椎を通過して嚥下が終了し、最小となった後、緩やかに通常の口角間距離Lに戻るという共通点が観測された。したがって、嚥下中の体表面動態がこの変動パターンに従っていない場合には、被検者Pの嚥下機能に何らかの障害が発生していることを疑うことができる。 Thus, it was confirmed that when there are many samples (water) to be held, there is a tendency to hold the samples (water) in the entire oral cavity. Summing up the data so far, the inter-oral distance L during the swallowing operation generally becomes the maximum after a while after the swallowing instruction, and the sample passes through the fourth cervical vertebra while decreasing thereafter, and the swallowing is finished Then, after reaching the minimum, a common point was observed in which the distance gradually returned to the normal distance L between the mouth corners. Therefore, when the body surface dynamics during swallowing do not follow this variation pattern, it can be suspected that some kind of disorder has occurred in the swallowing function of the subject P.
 しかしながら、厳密に言えば、口角間距離Lの変動パターンは被検者Pによって異なるため、より的確な嚥下機能の評価を行うため、同期データ生成部13は被検者P毎に同期データ7を生成し、分析部14は被検者P毎の同期データ7を用いて、その同期データ7に基づいて被検者Pの嚥下機能を分析するのが望ましい。図16では、分析部14が記憶部14Cを備え、記憶部14Cに、被検者PAの同期データ7Aと、被検者PBの同期データ7Bと、被検者PCの同期データ7Cが記憶されている例が示されている。 Strictly speaking, however, the variation pattern of the inter-oral distance L varies depending on the subject P. Therefore, in order to evaluate the swallowing function more accurately, the synchronization data generating unit 13 generates the synchronization data 7 for each subject P. It is desirable that the analyzing unit 14 uses the synchronization data 7 for each subject P and analyzes the swallowing function of the subject P based on the synchronization data 7. In FIG. 16, the analysis unit 14 includes a storage unit 14C, and the synchronization data 7A of the subject PA, the synchronization data 7B of the subject PB, and the synchronization data 7C of the subject PC are stored in the storage unit 14C. An example is shown.
 図16に示すように、分析部14は、被検者PA~PCにおける嚥下動作中の体表面動態を撮像して取得された体表面動態データ11Dと、同期データ7A~7Cとに基づいて、被検者PA~PCの嚥下機能の状態を推定するようにしてもよい。嚥下機能検査システム1は、通信ネットワーク9を介して、被検者PA,PB,PCの自宅8に設置された3次元形状計測装置4に接続されているものとする。被検者PAの自宅8に設置された3次元形状計測装置4で被検者PAの体表面動態データ11Dが取得されると、そのデータは、通信ネットワーク9を介して、嚥下機能検査システム1に送信される。 As shown in FIG. 16, the analysis unit 14 is based on the body surface dynamics data 11D acquired by imaging the body surface dynamics during the swallowing motion in the subjects PA to PC, and the synchronization data 7A to 7C. The state of the swallowing function of the subjects PA to PC may be estimated. It is assumed that the swallowing function test system 1 is connected to a three-dimensional shape measuring device 4 installed in a home 8 of the subject PA, PB, or PC via a communication network 9. When the body surface dynamics data 11D of the subject PA is acquired by the three-dimensional shape measuring apparatus 4 installed in the home 8 of the subject PA, the data is transferred to the swallowing function test system 1 via the communication network 9. Sent to.
 嚥下機能検査システム1の分析部14は、被検者PAの体表面動態データ11Dに基づいて、現在の被検者PAの嚥下機能の状態を推定する。例えば、受信した体表面動態データ11Dから得られる口角間距離Lの変動パターンと、同期データ7Aとして記憶された口角簡距離Lの変動パターンとが大きくなる場合(例えば、嚥下時間が長い場合や激しく変動する場合)には、被検者PAに摂食嚥下障害が発生した可能性があると推定する。このような推定結果が出れば、被検者PAに対してより精密な診断を行うことができるようになる。これは、被検者PB,PCについても同様である。このような仕組みを構築すれば、在宅診療が可能となり、被検者P等の負担は著しく軽減される。 The analysis unit 14 of the swallowing function test system 1 estimates the current swallowing function state of the subject PA based on the body surface dynamics data 11D of the subject PA. For example, when the variation pattern of the inter-oral distance L obtained from the received body surface dynamics data 11D and the variation pattern of the easy-to-mouth distance L stored as the synchronization data 7A become large (for example, when the swallowing time is long or intense If it fluctuates), it is estimated that there is a possibility that a dysphagia has occurred in the subject PA. If such an estimation result is obtained, a more accurate diagnosis can be performed on the subject PA. The same applies to the subjects PB and PC. If such a mechanism is constructed, home medical care can be performed, and the burden on the subject P or the like is remarkably reduced.
 以上詳細に説明したように、本実施の形態によれば、嚥下動作中の被検者Pの体表面動態データ11Dと内部動態データ12Dとの同期データ7を生成するので、後から嚥下動作中の被検者Pの体表面動態を測定するだけで、被検者Pの嚥下機能の状態を推定することができる。このため、被検者Pの嚥下機能を、安価、簡便、非侵襲的かつ的確に検査することができる。 As described above in detail, according to the present embodiment, the synchronization data 7 between the body surface dynamics data 11D and the internal dynamics data 12D of the subject P during the swallowing operation is generated. The state of the swallowing function of the subject P can be estimated simply by measuring the body surface dynamics of the subject P. For this reason, the swallowing function of the subject P can be examined inexpensively, simply, noninvasively and accurately.
 上記実施の形態では、被検者Pの口角間距離Lを、嚥下機能を評価する特定の部位として用いたが、本発明はこれには限られない。嚥下動作に関する体表面動態に関する情報であれば、嚥下機能の評価に用いることが可能である。例えば、被検者Pの前頭部、眉間、鼻部、オトガイ部、前頚部を特定部位として採用してその動きを計測するようにしてもよい。 In the above embodiment, the inter-oral distance L of the subject P is used as a specific part for evaluating the swallowing function, but the present invention is not limited to this. Information on body surface dynamics related to swallowing motion can be used for evaluation of swallowing function. For example, the forehead, eyebrow, nose, chin portion, and front neck of the subject P may be adopted as specific portions and the movement thereof may be measured.
 また、上記実施の形態では、タイミング情報として音を用いたが、本発明はこれには限られない。タイミング情報として光を用いてもよい。また、バイブレータを用いて被検者Pにタイミングを報知するようにしてもよい。これらの場合、光源を発光させたりバイブレータを駆動させたりする電気信号をタイミング情報として体表面動態及び内部動態とともに記録すればよい。 In the above embodiment, sound is used as timing information, but the present invention is not limited to this. Light may be used as timing information. Moreover, you may make it alert | report a timing to the subject P using a vibrator. In these cases, an electrical signal for causing the light source to emit light or driving the vibrator may be recorded as timing information together with body surface dynamics and internal dynamics.
 上記実施の形態では、時点T1、T2のタイミングで体表面動態データ11Dと内部動態データ12Dとを同期させたが、時点T2だけで、両データ11D,12Dを同期させるようにしてもよい。 In the above embodiment, the body surface dynamic data 11D and the internal dynamic data 12D are synchronized at the timing of the time points T1 and T2. However, the data 11D and 12D may be synchronized only at the time point T2.
 上記実施の形態では、被検者Pが嚥下する試料を水としたが、本発明はこれには限られない。他の飲料であってもよい。 In the above embodiment, the sample swallowed by the subject P is water, but the present invention is not limited to this. Other beverages may be used.
 その他、嚥下機能検査システム1のハードウエア構成やソフトウエア構成は一例であり、任意に変更および修正が可能である。 In addition, the hardware configuration and software configuration of the swallowing function test system 1 are examples, and can be arbitrarily changed and modified.
 制御部31、主記憶部32、外部記憶部33、操作部34、表示部35、通信部36及び内部バス30などから構成される嚥下機能検査システム1の処理を行う中心となる部分は、専用のシステムによらず、通常のコンピュータシステムを用いて実現可能である。例えば、前記の動作を実行するためのコンピュータプログラムを、コンピュータが読み取り可能な記録媒体(フレキシブルディスク、CD-ROM、DVD-ROM等)に格納して配布し、当該コンピュータプログラムをコンピュータにインストールすることにより、前記の処理を実行する嚥下機能検査システム1を構成してもよい。また、インターネット等の通信ネットワーク上のサーバ装置が有する記憶装置に当該コンピュータプログラムを格納しておき、通常のコンピュータシステムがダウンロード等することで嚥下機能検査システム1を構成してもよい。 A central part that performs processing of the swallowing function test system 1 including the control unit 31, the main storage unit 32, the external storage unit 33, the operation unit 34, the display unit 35, the communication unit 36, the internal bus 30, and the like is dedicated. It can be realized using a normal computer system regardless of the system. For example, a computer program for executing the above operation is stored and distributed in a computer-readable recording medium (flexible disk, CD-ROM, DVD-ROM, etc.), and the computer program is installed in the computer. Thus, the swallowing function test system 1 that executes the above-described processing may be configured. The computer program may be stored in a storage device included in a server device on a communication network such as the Internet, and the swallowing function test system 1 may be configured by downloading or the like from a normal computer system.
 嚥下機能検査システム1の機能を、OS(オペレーティングシステム)とアプリケーションプログラムの分担、またはOSとアプリケーションプログラムとの協働により実現する場合などには、アプリケーションプログラム部分のみを記録媒体や記憶装置に格納してもよい。 When the function of the swallowing function test system 1 is realized by sharing an OS (operating system) and an application program, or in cooperation with the OS and the application program, only the application program part is stored in a recording medium or a storage device. May be.
 搬送波にコンピュータプログラムを重畳し、通信ネットワークを介して配信することも可能である。例えば、通信ネットワーク上の掲示板(BBS, Bulletin Board System)にコンピュータプログラムを掲示し、ネットワークを介してコンピュータプログラムを配信してもよい。そして、このコンピュータプログラムを起動し、OSの制御下で、他のアプリケーションプログラムと同様に実行することにより、前記の処理を実行できるように構成してもよい。 It is also possible to superimpose a computer program on a carrier wave and distribute it via a communication network. For example, a computer program may be posted on a bulletin board (BBS, “Bulletin“ Board System ”) on a communication network, and the computer program distributed via the network. The computer program may be started and executed in the same manner as other application programs under the control of the OS, so that the above-described processing may be executed.
 この発明は、この発明の広義の精神と範囲を逸脱することなく、様々な実施の形態及び変形が可能とされるものである。また、上述した実施の形態は、この発明を説明するためのものであり、この発明の範囲を限定するものではない。すなわち、この発明の範囲は、実施の形態ではなく、特許請求の範囲によって示される。そして、特許請求の範囲内及びそれと同等の発明の意義の範囲内で施される様々な変形が、この発明の範囲内とみなされる。 The present invention is capable of various embodiments and modifications without departing from the broad spirit and scope of the present invention. The above-described embodiments are for explaining the present invention and do not limit the scope of the present invention. In other words, the scope of the present invention is shown not by the embodiments but by the claims. Various modifications within the scope of the claims and within the scope of the equivalent invention are considered to be within the scope of the present invention.
 なお、本願については、2017年4月18日に出願された日本国特許出願2017-82001号を基礎とする優先権を主張し、本明細書中に日本国特許出願2017-82001号の明細書、特許請求の範囲、図面全体を参照として取り込むものとする。 The present application claims priority based on Japanese Patent Application No. 2017-82001 filed on April 18, 2017, and the specification of Japanese Patent Application No. 2017-82001 is included in this specification. The claims and the entire drawing are incorporated by reference.
 本発明は、嚥下機能の検査に適用することができる。特に、在宅医療で嚥下機能を診断する場合などに適用することができる。 The present invention can be applied to the examination of swallowing function. In particular, it can be applied when diagnosing the swallowing function in home medical care.
 1 嚥下機能検査システム、2 検査室、3 スピーカ、4 3次元形状計測装置、5 造影検査装置、6 格子データ、7,7A,7B,7C 同期データ、8 自宅、9 通信ネットワーク、10 タイミング情報発生部、11 体表面動態取得部、11A 体表面動態情報生成部、11B 記憶部、11C 映像及び電子音データ、11D 体表面動態データ、12 内部動態取得部、12C 電子音データ、12D 内部動態データ、13 同期データ生成部、14 分析部、14C 記憶部、30 内部バス、31 制御部、32 主記憶部、33 外部記憶部、34 操作部、35 表示部、36 通信部、39 プログラム、P,P1,P2,PA,PB,PC 被検者 1 swallowing function test system, 2 test room, 3 speakers, 4 3D shape measuring device, 5 contrast test device, 6 grid data, 7, 7A, 7B, 7C synchronous data, 8 home, 9 communication network, 10 timing information generation 11, 11 body surface dynamics acquisition unit, 11A body surface dynamics information generation unit, 11B storage unit, 11C video and electronic sound data, 11D body surface dynamics data, 12 internal dynamics acquisition unit, 12C electronic sound data, 12D internal dynamics data, 13 synchronization data generation unit, 14 analysis unit, 14C storage unit, 30 internal bus, 31 control unit, 32 main storage unit, 33 external storage unit, 34 operation unit, 35 display unit, 36 communication unit, 39 program, P, P1 , P2, PA, PB, PC

Claims (8)

  1.  タイミング情報を発生させるタイミング情報発生部と、
     前記タイミング情報発生部でタイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得する体表面動態取得部と、
     前記タイミング情報発生部でタイミング情報が発生した時点を含み、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する内部動態取得部と、
     前記体表面動態データでタイミング情報が発生した時点と、前記内部動態データでタイミング情報が発生した時点とを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成部と、
     前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析部と、
     を備える嚥下機能検査システム。
    A timing information generator for generating timing information;
    The body surface dynamics acquisition unit that acquires the body surface dynamics data that operates along with the swallowing operation of the subject in the period when the swallowing operation is performed, including the time point when the timing information is generated in the timing information generating unit,
    An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including the time when the timing information is generated in the timing information generation unit;
    Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data A generator,
    Based on the synchronization data, an analysis unit that analyzes the correlation between the body surface dynamics and internal dynamics of the subject during the swallowing operation;
    A swallowing function inspection system.
  2.  前記分析部は、
     同一被検者における嚥下動作中の体表面動態を再度撮像して取得された体表面動態データと、前記同期データとに基づいて、被検者の嚥下機能の状態を推定する、
     請求項1に記載の嚥下機能検査システム。
    The analysis unit
    Estimating the state of swallowing function of the subject based on the body surface dynamics data obtained by imaging again the body surface dynamics during the swallowing motion in the same subject, and the synchronization data,
    The swallowing function test system according to claim 1.
  3.  前記分析部は、
     前記体表面動態データから得られる嚥下動作中の体表面上の特定の部位の動態に関する項目に基づいて、被検者の嚥下機能の状態を分析する、
     請求項1又は2に記載の嚥下機能検査システム。
    The analysis unit
    Analyzing the state of the swallowing function of the subject based on items related to the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamics data,
    The swallowing function test system according to claim 1 or 2.
  4.  前記特定の部位には、口角間距離が含まれる、
     請求項3に記載の嚥下機能検査システム。
    The specific part includes a distance between mouth corners,
    The swallowing function test system according to claim 3.
  5.  前記同期データ生成部は、
     被検者毎に、前記同期データを生成し、
     前記分析部は、
     被検者毎の同期データを用いて、当該同期データに対応する被検者の嚥下機能を分析する、
     請求項1から4のいずれか一項に記載の嚥下機能検査システム。
    The synchronous data generation unit
    For each subject, generate the synchronization data,
    The analysis unit
    Using the synchronization data for each subject, analyze the swallowing function of the subject corresponding to the synchronization data,
    The swallowing function test system according to any one of claims 1 to 4.
  6.  前記タイミング情報発生部は、前記タイミング情報として、音を発生させる、
     請求項1から5のいずれか一項に記載の嚥下機能検査システム。
    The timing information generating unit generates a sound as the timing information.
    The swallowing function test system according to any one of claims 1 to 5.
  7.  タイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得すると同時に、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する動態取得工程と、
     前記体表面動態データでタイミング情報が発生したタイミングと、前記内部動態データでタイミング情報が発生したタイミングとを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成工程と、
     前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析工程と、
     を含む嚥下機能分析方法。
    The body surface dynamics data that operates along with the swallowing motion of the subject in the period during which the swallowing motion is performed, including the time point when the timing information is generated, and at the same time, A dynamic acquisition process for acquiring internal dynamic data of the same subject operating along with the movement;
    Synchronous data for generating synchronous data of internal dynamics and body surface dynamics during the swallowing operation by combining timing when timing information is generated with the body dynamics data and timing when timing information is generated with the internal dynamic data Generation process;
    An analysis step for analyzing a correlation between body surface dynamics and internal dynamics of the subject during the swallowing motion based on the synchronization data;
    A method for analyzing swallowing function.
  8.  コンピュータを、
     タイミング情報を発生させるタイミング情報発生部、
     前記タイミング情報発生部でタイミング情報が発生した時点を含み、嚥下動作が行われた期間における被検者の嚥下動作に伴って動作する体表面動態データを取得する体表面動態取得部、
     前記タイミング情報発生部でタイミング情報が発生した時点を含み、前記嚥下動作が行われた期間における前記嚥下動作に伴って動作する同一被検者の内部動態データを取得する内部動態取得部、
     前記体表面動態データでタイミング情報が発生した時点と、前記内部動態データでタイミング情報が発生した時点とを合わせて、前記嚥下動作中における内部動態と体表面動態との同期データを生成する同期データ生成部、
     前記同期データに基づいて、前記嚥下動作中の被検者の体表面動態と内部動態との相関性を分析する分析部、
     として機能させるプログラム。
    Computer
    A timing information generator for generating timing information;
    A body surface dynamics acquisition unit for acquiring body surface dynamics data that operates in accordance with the swallowing motion of the subject in a period in which the swallowing motion is performed, including the time when the timing information is generated in the timing information generator;
    An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including a time point when the timing information is generated in the timing information generation unit;
    Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data Generator,
    Based on the synchronization data, an analysis unit that analyzes the correlation between body surface dynamics and internal dynamics of the subject during the swallowing operation,
    Program to function as.
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