WO2014091401A3 - Dynamic denervation procedures and systems for the implementation thereof - Google Patents

Dynamic denervation procedures and systems for the implementation thereof Download PDF

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Publication number
WO2014091401A3
WO2014091401A3 PCT/IB2013/060771 IB2013060771W WO2014091401A3 WO 2014091401 A3 WO2014091401 A3 WO 2014091401A3 IB 2013060771 W IB2013060771 W IB 2013060771W WO 2014091401 A3 WO2014091401 A3 WO 2014091401A3
Authority
WO
WIPO (PCT)
Prior art keywords
dynamic
implementation
systems
denervation procedures
denervation
Prior art date
Application number
PCT/IB2013/060771
Other languages
French (fr)
Other versions
WO2014091401A2 (en
Inventor
Boaz Behar
Original Assignee
Perseus-Biomed Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perseus-Biomed Inc. filed Critical Perseus-Biomed Inc.
Publication of WO2014091401A2 publication Critical patent/WO2014091401A2/en
Publication of WO2014091401A3 publication Critical patent/WO2014091401A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0036—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00702—Power or energy
    • A61B2018/00708—Power or energy switching the power on or off
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0285—Nanoscale sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • External Artificial Organs (AREA)
  • Electrotherapy Devices (AREA)
  • Surgical Instruments (AREA)

Abstract

A method of controlling a denervation procedure for ablating a sympathetic nerve. The method comprises measuring a level of at least one biochemical indicator in the blood circulation of a patient undergoing a denervation procedure for ablating at least one sympathetic nerve and controlling the denervation procedure according to the level.
PCT/IB2013/060771 2012-12-10 2013-12-10 Dynamic denervation procedures and systems for the implementation thereof WO2014091401A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261735085P 2012-12-10 2012-12-10
US61/735,085 2012-12-10

Publications (2)

Publication Number Publication Date
WO2014091401A2 WO2014091401A2 (en) 2014-06-19
WO2014091401A3 true WO2014091401A3 (en) 2014-11-13

Family

ID=50935045

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/060771 WO2014091401A2 (en) 2012-12-10 2013-12-10 Dynamic denervation procedures and systems for the implementation thereof

Country Status (1)

Country Link
WO (1) WO2014091401A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20070021803A1 (en) 2005-07-22 2007-01-25 The Foundry Inc. Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
CN103313671B (en) 2010-10-25 2017-06-06 美敦力Af卢森堡有限责任公司 Device, the system and method for estimation and feedback for nerve modulation treatment
EP3287067B1 (en) 2011-11-07 2019-10-30 Medtronic Ardian Luxembourg S.à.r.l. Endovascular nerve monitoring devices and associated systems
CA2856732A1 (en) 2011-12-09 2013-06-13 Metavention, Inc. Therapeutic neuromodulation of the hepatic system
CN104271062B (en) 2012-03-08 2017-07-07 美敦力Af卢森堡有限责任公司 Using the biomarker sampling of neuromodulation device and related system and method
EP2968919B1 (en) 2013-03-15 2021-08-25 Medtronic Ardian Luxembourg S.à.r.l. Controlled neuromodulation systems
US9339332B2 (en) 2013-08-30 2016-05-17 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters with nerve monitoring features for transmitting digital neural signals and associated systems and methods
US9326816B2 (en) 2013-08-30 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
WO2016033543A1 (en) 2014-08-28 2016-03-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for assessing efficacy of renal neuromodulation and associated systems and devices
US10368775B2 (en) 2014-10-01 2019-08-06 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for evaluating neuromodulation therapy via hemodynamic responses
WO2016100720A1 (en) 2014-12-17 2016-06-23 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing sympathetic nervous system tone for renal neuromodulation therapy
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
US10231784B2 (en) 2016-10-28 2019-03-19 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics
US11633120B2 (en) 2018-09-04 2023-04-25 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing efficacy of renal neuromodulation therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020117659A1 (en) * 2000-12-11 2002-08-29 Lieber Charles M. Nanosensors
US20100168731A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US20120116236A1 (en) * 2010-11-04 2012-05-10 Joshua Noel Hogan Hydration and blood flow adjusted glucose measurement
US20120191086A1 (en) * 2011-01-20 2012-07-26 Hansen Medical, Inc. System and method for endoluminal and translumenal therapy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020117659A1 (en) * 2000-12-11 2002-08-29 Lieber Charles M. Nanosensors
US20100168731A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US20120116236A1 (en) * 2010-11-04 2012-05-10 Joshua Noel Hogan Hydration and blood flow adjusted glucose measurement
US20120191086A1 (en) * 2011-01-20 2012-07-26 Hansen Medical, Inc. System and method for endoluminal and translumenal therapy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ESLER, MURRAY.: "The 2009 Carl Ludwig Lecture: pathophysiology of the human sympathetic nervous system in cardiovascular diseases: the transition from mechanisms to medical management", J APPL PHYSIOL., vol. 108, 25 November 2009 (2009-11-25), pages 227 - 237, Retrieved from the Internet <URL:http://jap.physiology.org/content/jap/108/2/227.full.pdf> [retrieved on 20140627] *
PAPADEMETRIOU, V ET AL.: "Renal Sympathetic Denervation for the Treatment of Difficult-to-Control or Resistant Hypertension.", INT J HYPERTENS., vol. 2011, 30 March 2011 (2011-03-30), pages 1 - 8, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095896/pdf/IJHT2011-196518.pdf> [retrieved on 20140627] *

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