WO2013132338A3 - Competitive immunoassay for calprotectin - Google Patents

Competitive immunoassay for calprotectin Download PDF

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Publication number
WO2013132338A3
WO2013132338A3 PCT/IB2013/000733 IB2013000733W WO2013132338A3 WO 2013132338 A3 WO2013132338 A3 WO 2013132338A3 IB 2013000733 W IB2013000733 W IB 2013000733W WO 2013132338 A3 WO2013132338 A3 WO 2013132338A3
Authority
WO
WIPO (PCT)
Prior art keywords
calprotectin
competitive
immunoassays
competitive immunoassay
immunoassay
Prior art date
Application number
PCT/IB2013/000733
Other languages
French (fr)
Other versions
WO2013132338A2 (en
Inventor
Magne FAGERHOL
Original Assignee
Calpro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpro As filed Critical Calpro As
Publication of WO2013132338A2 publication Critical patent/WO2013132338A2/en
Publication of WO2013132338A3 publication Critical patent/WO2013132338A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A competitive immunoassay for the S100A9 subunit of calprotectin is described; the immunoassay can be performed on a solid phase platform or a lateral flow platform. Also described are suitable assay devices for carrying out such competitive immunoassays, including lateral flow competitive immunoassays, and methods of use of such immunoassays in the diagnosis of inflammatory bowel disease.
PCT/IB2013/000733 2012-03-06 2013-03-05 Competitive immunoassay for calprotectin WO2013132338A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261607257P 2012-03-06 2012-03-06
US61/607,257 2012-03-06

Publications (2)

Publication Number Publication Date
WO2013132338A2 WO2013132338A2 (en) 2013-09-12
WO2013132338A3 true WO2013132338A3 (en) 2014-03-27

Family

ID=48539302

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/000733 WO2013132338A2 (en) 2012-03-06 2013-03-05 Competitive immunoassay for calprotectin

Country Status (1)

Country Link
WO (1) WO2013132338A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104597255B (en) * 2015-02-04 2017-07-21 华中农业大学 The test card and preparation method and application of pseudorabies virus gE protein antibodies in a kind of detection Swine serum
FR3033410B1 (en) * 2015-03-06 2017-03-31 Laboratoire Hra-Pharma DEVICE FOR IDENTIFYING THE INFERTILE PERIOD OF A WOMAN
JP6192177B2 (en) * 2015-05-25 2017-09-06 ヤマサ醤油株式会社 Use of S100A9 as a biomarker for inflammatory bowel disease
CN105181958B (en) * 2015-09-08 2017-07-11 安徽师范大学 A kind of method that 80nmAuNPs is quantitatively detected based on Indirect cELISA
JP6909208B2 (en) 2015-09-17 2021-07-28 アムジェン インコーポレイテッド Prediction of clinical response to IL23 antagonists using IL23 pathway biomarkers
CN105181977A (en) * 2015-11-05 2015-12-23 四川沃文特生物技术有限公司 Kit for detecting calprotectin in excrement
EP3176580A1 (en) 2015-12-01 2017-06-07 Roche Diagnostics GmbH Method for reduction of interferences in immunoassays
CN108472367A (en) 2015-12-22 2018-08-31 美国安进公司 The CCL20 of predictive factor as the clinical response to IL23 antagonists
CA3068038A1 (en) * 2017-06-28 2019-01-03 Becton, Dickinson And Company Sandwich-type assays using decreasing signal portions of dose response curve to measure analytes, including analytes at high concentration
CN108196066A (en) * 2018-01-22 2018-06-22 安徽伊普诺康生物技术股份有限公司 A kind of kit for measuring calcium sozin and its preparation application method
AU2019212378A1 (en) * 2018-01-27 2020-07-30 Becton, Dickinson And Company Multiplex lateral flow assay for differentiating bacterial infections from viral infections
CN116500020A (en) * 2018-08-13 2023-07-28 科美博阳诊断技术(上海)有限公司 Chemiluminescence analysis method and application thereof
CN109212184B (en) * 2018-09-08 2022-08-26 苏州承美生物科技有限公司 One-step calprotectin rapid detection kit
CN109682979A (en) * 2019-01-30 2019-04-26 珠海市银科医学工程股份有限公司 A kind of calprotectin joint lactoferrin antigen test strip and preparation method thereof
CN110488025A (en) * 2019-09-24 2019-11-22 嘉兴行健生物科技有限公司 A kind of chemiluminescence quantitative detection excrement calprotectin and its detection method and its intestinal health detection purposes
CN110609143A (en) * 2019-10-31 2019-12-24 苏州普瑞森基因科技有限公司 Calprotectin heterodimer detection kit and application thereof
CN111190004B (en) * 2020-01-10 2023-11-10 上海泰辉生物科技有限公司 Instant detection system of immunochromatography test strip
IT202000016714A1 (en) * 2020-07-09 2022-01-09 I R C C S Centro Neurolesi Bonino Pulejo METHOD OF DIAGNOSIS OF INFLAMMATORY INTESTINAL DISEASES
WO2023147522A1 (en) * 2022-01-28 2023-08-03 GATC Health Corp Biomarkers for early detection of diabetes
CN117607461A (en) * 2023-12-06 2024-02-27 陕西省动物研究所 Detection method of S100A8 protein and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008097773A1 (en) * 2007-02-02 2008-08-14 Aspenbio Pharma, Inc. Methods and devices for diagnosis of appendicitis
WO2012175616A1 (en) * 2011-06-21 2012-12-27 Calpro As Competitive s100a9 immunoassays

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
US4943522A (en) 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US4956302A (en) 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
FI92882C (en) 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Disposable test strip and process for its manufacture
US5552292A (en) 1993-01-18 1996-09-03 Ikagaku Co., Ltd. Method of screening for colorectal cancer
US20010051350A1 (en) 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
WO1997006439A1 (en) 1995-08-09 1997-02-20 Quidel Corporation Test strip and method for one step lateral flow assay
US5710005A (en) 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
PT937259E (en) 1996-11-01 2005-01-31 Magne K Fagerhol PROCESS FOR EXTRACTION OF PROTEINS
US6174664B1 (en) 1997-02-05 2001-01-16 University Of Pittsburgh Screening method for inflammatory diseases using neutrophil defensins and lactoferrin
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
US6319466B1 (en) 1997-07-16 2001-11-20 Charm Sciences, Inc. Test device for detecting the presence of a residue analyte in a sample
US6136610A (en) 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
US6297020B1 (en) 1999-03-01 2001-10-02 Bayer Corporation Device for carrying out lateral-flow assays involving more than one analyte
US6528323B1 (en) 1999-06-14 2003-03-04 Praxsys Biosystems, Inc. Bidirectional lateral flow test strip and method
EP1425578A2 (en) 1999-09-13 2004-06-09 Equitech Laboratories, Inc. Materials and methods for the determination of an analyte
US6727073B1 (en) 1999-11-19 2004-04-27 Binax, Inc. Method for detecting enteric disease
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
GB2365526B (en) 2000-07-31 2003-12-03 Cambridge Life Sciences Assay apparatus for measuring the amount of an analyte in a biological or environmental sample
US7192724B2 (en) 2000-11-14 2007-03-20 Techlab, Inc. Method for differentiating irritable bowel syndrome from inflammatory bowel disease (IBD) and for monitoring persons with IBD using total endogenous lactoferrin as a marker
US6981522B2 (en) 2001-06-07 2006-01-03 Nanostream, Inc. Microfluidic devices with distributing inputs
US7205159B2 (en) 2001-08-20 2007-04-17 Proteome Systems Intellectual Property Pty Ltd. Diagnostic testing process and apparatus
US7166208B2 (en) 2004-03-03 2007-01-23 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US6841159B2 (en) 2002-01-30 2005-01-11 The United States Of America As Represented By The Secretary Of The Navy Rapid lateral flow assay for determining exposure to Mycobacterium tuberculosis and other mycobacteria
US7256053B2 (en) 2002-10-24 2007-08-14 Nanogen, Inc. Diagnostic device for analyte detection
CA2502976C (en) 2002-10-25 2012-05-22 Techlab, Inc. Inflammatory bowel disease and irritable bowel syndrome ibd-first chek diagnostic panel
JP4258246B2 (en) 2003-03-28 2009-04-30 豊田合成株式会社 Weather strip and manufacturing method thereof
US7186566B2 (en) 2003-07-28 2007-03-06 Suyue Qian Combining transmittance detection and chromatographic strip techniques for quantification of analyte in biological fluids
US7238538B2 (en) 2003-09-19 2007-07-03 Freitag Helmut E Chromatographic assay device and methods
US7090803B1 (en) 2003-10-28 2006-08-15 American Bio Medica Corporation Lateral flow immunoassay device
US7238322B2 (en) 2004-01-28 2007-07-03 Dnt Scientific Research, Llc Delayed and diffused flow rapid confirmatory immunological testing apparatus and method
US7759079B2 (en) 2004-05-13 2010-07-20 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20090053736A1 (en) 2007-08-21 2009-02-26 Mattingly Phillip G Homogeneous Chemiluminescent Immunoassay for Analysis of Iron Metalloproteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008097773A1 (en) * 2007-02-02 2008-08-14 Aspenbio Pharma, Inc. Methods and devices for diagnosis of appendicitis
WO2012175616A1 (en) * 2011-06-21 2012-12-27 Calpro As Competitive s100a9 immunoassays

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