WO2011159537A3 - Method and device for analyte detection - Google Patents
Method and device for analyte detection Download PDFInfo
- Publication number
- WO2011159537A3 WO2011159537A3 PCT/US2011/039629 US2011039629W WO2011159537A3 WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3 US 2011039629 W US2011039629 W US 2011039629W WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analyte detection
- combining
- lateral
- point
- provides
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention provides a method and a point-of-care device for detecting analytes by combining a complex fluid system with the lateral-flow immunoassay.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35494010P | 2010-06-15 | 2010-06-15 | |
US61/354,940 | 2010-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011159537A2 WO2011159537A2 (en) | 2011-12-22 |
WO2011159537A3 true WO2011159537A3 (en) | 2012-05-31 |
Family
ID=45348796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/039629 WO2011159537A2 (en) | 2010-06-15 | 2011-06-08 | Method and device for analyte detection |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011159537A2 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102662015B (en) * | 2012-04-12 | 2013-11-20 | 湖南师范大学 | Biological sample purification method based on inorganic salt promoted phase transition and separation of nano-gold |
PL2888592T3 (en) | 2012-08-21 | 2018-03-30 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
ES2807902T3 (en) | 2012-08-21 | 2021-02-24 | Janssen Pharmaceutica Nv | Antibodies to olanzapine and their use |
EP2888277A4 (en) | 2012-08-21 | 2016-05-18 | Ortho Clinical Diagnostics Inc | Antibodies to paliperidone and use thereof |
JP2015529199A (en) | 2012-08-21 | 2015-10-05 | オルソ−クリニカル ダイアグノスティクス,インコーポレイティド | Antibodies against paliperidone hapten and use thereof |
PL3462173T3 (en) | 2012-08-21 | 2021-08-16 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
PL2888286T3 (en) | 2012-08-21 | 2018-07-31 | Janssen Pharmaceutica Nv | Antibodies to quetiapine haptens and use thereof |
ES2822914T3 (en) | 2012-08-21 | 2021-05-05 | Janssen Pharmaceutica Nv | Aripiprazole haptens and its use in immunoassays |
AU2013305970B2 (en) | 2012-08-21 | 2017-08-17 | Saladax Biomedical Inc. | Antibodies to aripiprazole haptens and use thereof |
EP3581195A1 (en) | 2012-08-21 | 2019-12-18 | Janssen Pharmaceutica NV | Antibodies to olanzapine haptens and use thereof |
EP2888284B1 (en) | 2012-08-21 | 2022-07-06 | Janssen Pharmaceutica NV | Antibodies to risperidone haptens and use thereof |
PT2888373T (en) | 2012-08-21 | 2018-06-12 | Janssen Pharmaceutica Nv | Antibodies to aripiprazole and use thereof |
CN103675264B (en) * | 2013-12-05 | 2015-08-19 | 美艾利尔(上海)诊断产品有限公司 | A kind of colloidal gold film for detecting antibody on sensitization nitrocellulose filter and its preparation method and application |
KR102630880B1 (en) | 2014-03-07 | 2024-01-29 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | Devices for integrating analyte extraction, concentration and detection |
CN104678093A (en) * | 2015-03-20 | 2015-06-03 | 上海理工大学 | Preparation method of immobilized anti-clenbuterol hydrochloride monoclonal antibody |
CA3002020C (en) | 2015-09-04 | 2024-02-27 | The Regents Of The University Of California | Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications |
WO2017106501A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
JP6994461B2 (en) | 2015-12-17 | 2022-02-04 | ヤンセン ファーマシューティカ エヌ.ベー. | Antibodies to quetiapine and their use |
KR102592388B1 (en) * | 2016-06-09 | 2023-10-20 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | A single platform for biomarker enrichment and signal amplification for use in paper-based immunoassays, and for extraction, concentration and amplification of DNA. |
WO2018039139A1 (en) | 2016-08-22 | 2018-03-01 | The Regents Of The University Of California | Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection |
WO2018183211A1 (en) | 2017-03-27 | 2018-10-04 | The Regents Of The University Of California | Semi-quantitative lateral-flow immunoassay for the detection of csf leaks |
ES2954376T3 (en) | 2017-03-28 | 2023-11-21 | Phase Scient International Ltd | Method to accurately diagnose a disease using biomarkers of interest in a liquid biopsy |
WO2018183454A1 (en) * | 2017-03-28 | 2018-10-04 | Chiu Yin To | Method and device for accurate diagnosis of dental diseases |
US20200150116A1 (en) * | 2017-05-31 | 2020-05-14 | The Regents Of The University Of California | Single-step atps enhanced lfa diagnostic design |
CN114632349A (en) | 2017-06-01 | 2022-06-17 | 相达生物科技美国有限公司 | Phase separation behavior modifier for aqueous two-phase separation in porous materials |
WO2019046563A1 (en) | 2017-09-01 | 2019-03-07 | Phase Diagnostics, Inc. | Method and device of using aqueous two-phase systems (atps) for enhancing diagnostics for sexually transmitted infections |
WO2019144030A1 (en) | 2018-01-19 | 2019-07-25 | Yin To Chiu | Method for isolating and purifying nucleic acids using a solid-liquid phase system |
WO2019143943A2 (en) | 2018-01-19 | 2019-07-25 | Yin To Chiu | Composition and method for concentration and enrichment of nucleic acids |
WO2019144016A1 (en) | 2018-01-19 | 2019-07-25 | Yin To Chiu | Method of isolating exosomes using encapsulation and aqueous micellar system |
CA3183061A1 (en) * | 2020-06-15 | 2021-12-23 | Neuome Peptides Pte. Ltd. | Lateral flow assay device for detection of analytes and method of detection thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5304310A (en) * | 1990-01-18 | 1994-04-19 | Basf Aktiengesellschaft | Method for concentrating and purifying hirudin from leeches |
US5772888A (en) * | 1995-07-27 | 1998-06-30 | Massachusetts Institute Of Technology | Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system |
US5798273A (en) * | 1996-09-25 | 1998-08-25 | Becton Dickinson And Company | Direct read lateral flow assay for small analytes |
US6699722B2 (en) * | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
-
2011
- 2011-06-08 WO PCT/US2011/039629 patent/WO2011159537A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5304310A (en) * | 1990-01-18 | 1994-04-19 | Basf Aktiengesellschaft | Method for concentrating and purifying hirudin from leeches |
US5772888A (en) * | 1995-07-27 | 1998-06-30 | Massachusetts Institute Of Technology | Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system |
US5798273A (en) * | 1996-09-25 | 1998-08-25 | Becton Dickinson And Company | Direct read lateral flow assay for small analytes |
US6699722B2 (en) * | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
Non-Patent Citations (1)
Title |
---|
MASHAYEKHI, F. ET AL.: "Enhancing the Lateral-flow Immunoassay for Viral Detection Using an Aqueous Two-phase Micellar System", ANAL. BIOANAL. CHEM., vol. 398, no. 7-8, September 2010 (2010-09-01), pages 2955 - 2961 * |
Also Published As
Publication number | Publication date |
---|---|
WO2011159537A2 (en) | 2011-12-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2011159537A3 (en) | Method and device for analyte detection | |
IL256307B (en) | Methods and systems for detecting an analyte or classifying a sample | |
WO2008135862A3 (en) | Devices and methods for detecting analytes | |
WO2013134741A3 (en) | Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results | |
WO2014058760A3 (en) | Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making | |
WO2011093602A3 (en) | Centrifugal micro-fluidic device and method for detecting analytes from liquid specimen | |
WO2013096822A3 (en) | Test device for optical and electrochemical assays | |
WO2012170435A3 (en) | Diagnostic devices, methods and systems for detecting platelet factor 4 (pf4)/heparin antibodies | |
BR112014018831A2 (en) | method for optimizing sensitivity and / or selectivity of a sensor for one or more analytes, method for forming a sensor for one or more analytes, detection kit for one or more analytes, method for identifying an aptamer, composition of matter and aptamers . | |
WO2011150115A3 (en) | Methods and apparatus for point-of-care detection of nucleic acid in a sample | |
WO2012045012A3 (en) | Sandwich assays in droplets | |
WO2010096674A3 (en) | A+ biomarker assays | |
EP2857837A4 (en) | Freeze-drying conjugate-construct for point-of-care testing immunochromatography, a kit for immunoassay using the same, and a method for analysis using the kit | |
WO2010065568A3 (en) | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 | |
BR112013008602A2 (en) | immunochromatographic device, method for the determination of a gene carrier, method for the diagnosis, method for the immunoassay, method for the detection and determination of the presence of a protein and kit | |
ATE493290T1 (en) | ALCOTEST DEVICE | |
WO2008007242A3 (en) | Increased specificity of analyte detection by measurement of bound and unbound labels | |
WO2013083781A3 (en) | Biomarkers and test panels useful in systemic inflammatory conditions | |
WO2012170206A3 (en) | Color-producing diagnostic systems, reagents and methods | |
EP3165560A4 (en) | Resin-metal composite, labeling substance, immunoassay method, immunoassay reagent, method for measuring analyte, analyte measurement kit, and lateral-flow chromatographic test strip | |
EP2279413A4 (en) | Methods, antibodies and kits for detecting cerebrospinal fluid in a sample | |
BRPI1015212A2 (en) | device and method for the detection and quantitative analysis of analytes, especially mycotoxins | |
WO2012025637A9 (en) | An agglutination assay method and device | |
EP3415912A4 (en) | Analyte detection method and reagent kit for detecting analyte | |
WO2009121024A3 (en) | Methods for detecting antibodies |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 11796198 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 11796198 Country of ref document: EP Kind code of ref document: A2 |