WO2011123779A1 - Thérapie cellulaire pour améliorer la cicatrisation des plaies et compositions et méthodes associées - Google Patents

Thérapie cellulaire pour améliorer la cicatrisation des plaies et compositions et méthodes associées Download PDF

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Publication number
WO2011123779A1
WO2011123779A1 PCT/US2011/030939 US2011030939W WO2011123779A1 WO 2011123779 A1 WO2011123779 A1 WO 2011123779A1 US 2011030939 W US2011030939 W US 2011030939W WO 2011123779 A1 WO2011123779 A1 WO 2011123779A1
Authority
WO
WIPO (PCT)
Prior art keywords
cells
wound
menses
derived stem
seeded
Prior art date
Application number
PCT/US2011/030939
Other languages
English (en)
Inventor
Mercedes A. Walton
Julie G. Allickson
Rolando O. Garcia-Morales
Original Assignee
Cryo-Cell International, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryo-Cell International, Inc. filed Critical Cryo-Cell International, Inc.
Priority to JP2013502888A priority Critical patent/JP2013523774A/ja
Priority to CA2795248A priority patent/CA2795248A1/fr
Priority to EP11763511.0A priority patent/EP2553089A4/fr
Publication of WO2011123779A1 publication Critical patent/WO2011123779A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention a pour objet des compositions thérapeutiques permettant d'améliorer la cicatrisation des plaies, des procédés de formulation associés et des méthodes d'utilisation associées. Les compositions thérapeutiques comprennent un dosage de MSC ensemencées,au choix, sur une matrice biodégradable, un gel, ou une solution convenant pour une injection sous-cutanée. Le dosage des MSC peut être compris dans une plage d'environ 1 X 106 MSC à environ 1 X 1010 par administration. Le régime d'administration peut être quotidien, hebdomadaire ou mensuel. Le dosage et les intervalles de traitement peuvent être ajustés en fonction de la réponse d'un patient au traitement. Les compositions thérapeutiques peuvent être co-administrées, par exemple, une application topique d'une matrice ou d'un gel ensemencé combinée à une injection sous-cutanée simultanée ou autrement périodique de MSC.
PCT/US2011/030939 2010-04-01 2011-04-01 Thérapie cellulaire pour améliorer la cicatrisation des plaies et compositions et méthodes associées WO2011123779A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2013502888A JP2013523774A (ja) 2010-04-01 2011-04-01 創傷治癒を改善する細胞治療並びに関連する組成物及び方法
CA2795248A CA2795248A1 (fr) 2010-04-01 2011-04-01 Therapie cellulaire pour ameliorer la cicatrisation des plaies et compositions et methodes associees
EP11763511.0A EP2553089A4 (fr) 2010-04-01 2011-04-01 Thérapie cellulaire pour améliorer la cicatrisation des plaies et compositions et méthodes associées

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34165210P 2010-04-01 2010-04-01
US61/341,652 2010-04-01

Publications (1)

Publication Number Publication Date
WO2011123779A1 true WO2011123779A1 (fr) 2011-10-06

Family

ID=44712651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/030939 WO2011123779A1 (fr) 2010-04-01 2011-04-01 Thérapie cellulaire pour améliorer la cicatrisation des plaies et compositions et méthodes associées

Country Status (4)

Country Link
EP (1) EP2553089A4 (fr)
JP (1) JP2013523774A (fr)
CA (1) CA2795248A1 (fr)
WO (1) WO2011123779A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016036322A1 (fr) 2014-09-04 2016-03-10 Kemijski inštitut Dispositif à base de cellules pour traitement local utilisant des protéines thérapeutiques
CN106074605A (zh) * 2016-07-28 2016-11-09 广州赛莱拉干细胞科技股份有限公司 一种修复皮肤溃疡的组合物及其制备方法
CN106176813A (zh) * 2016-07-28 2016-12-07 广州赛莱拉干细胞科技股份有限公司 一种修复皮肤溃疡的组合物及其制备方法
CN110693911A (zh) * 2019-10-30 2020-01-17 南通大学 经血源性子宫内膜干细胞制剂及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090053182A1 (en) * 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same
US20100008973A1 (en) * 2007-07-17 2010-01-14 University Of Massachusetts Medical School Compositions And Methods For Wound Healing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006230316A (ja) * 2005-02-25 2006-09-07 Japan Health Science Foundation 瘢痕のない創傷治癒能を有する細胞およびその調製方法
AR065584A1 (es) * 2007-03-01 2009-06-17 Cryo Cell Internat Inc Obtencion aislamiento y crioconservacion de celulas endometriales / menstruales
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090053182A1 (en) * 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same
US20100008973A1 (en) * 2007-07-17 2010-01-14 University Of Massachusetts Medical School Compositions And Methods For Wound Healing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2553089A4 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016036322A1 (fr) 2014-09-04 2016-03-10 Kemijski inštitut Dispositif à base de cellules pour traitement local utilisant des protéines thérapeutiques
CN106074605A (zh) * 2016-07-28 2016-11-09 广州赛莱拉干细胞科技股份有限公司 一种修复皮肤溃疡的组合物及其制备方法
CN106176813A (zh) * 2016-07-28 2016-12-07 广州赛莱拉干细胞科技股份有限公司 一种修复皮肤溃疡的组合物及其制备方法
CN110693911A (zh) * 2019-10-30 2020-01-17 南通大学 经血源性子宫内膜干细胞制剂及其制备方法和应用

Also Published As

Publication number Publication date
EP2553089A1 (fr) 2013-02-06
JP2013523774A (ja) 2013-06-17
EP2553089A4 (fr) 2013-10-23
CA2795248A1 (fr) 2011-10-06

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