WO2011069145A3 - Blood collection tube with separation barrier - Google Patents

Blood collection tube with separation barrier Download PDF

Info

Publication number
WO2011069145A3
WO2011069145A3 PCT/US2010/059023 US2010059023W WO2011069145A3 WO 2011069145 A3 WO2011069145 A3 WO 2011069145A3 US 2010059023 W US2010059023 W US 2010059023W WO 2011069145 A3 WO2011069145 A3 WO 2011069145A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood collection
collection tube
separation barrier
porous material
material separator
Prior art date
Application number
PCT/US2010/059023
Other languages
French (fr)
Other versions
WO2011069145A2 (en
Inventor
Girish Parmar
Hans-Peter Wahl
Kirk Swenson
Benjamin Bartfeld
Shenika E. Felix
John Hitchings
Robert G. Ellis
James C. Schneider
Bradley M. Wilkinson
Original Assignee
Becton, Dickinson And Company
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton, Dickinson And Company, F. Hoffmann-La Roche Ag filed Critical Becton, Dickinson And Company
Publication of WO2011069145A2 publication Critical patent/WO2011069145A2/en
Publication of WO2011069145A3 publication Critical patent/WO2011069145A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/029—Separating blood components present in distinct layers in a container, not otherwise provided for
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention relates to improved fluid collection containment devices and methods, utilizing a porous material separator that provides no or an acceptable level of interference with common diagnostic analytes. According to an aspect of the invention, the porous material separator (22) is disposed in the tube (10) in a predetermined position after centrifugation with a geometry that facilitates a sufficient separation of a blood sample while enabling usage in diagnostic blood testing.
PCT/US2010/059023 2009-12-04 2010-12-06 Blood collection tube with separation barrier WO2011069145A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26685909P 2009-12-04 2009-12-04
US61/266,859 2009-12-04

Publications (2)

Publication Number Publication Date
WO2011069145A2 WO2011069145A2 (en) 2011-06-09
WO2011069145A3 true WO2011069145A3 (en) 2011-08-25

Family

ID=43639159

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/059023 WO2011069145A2 (en) 2009-12-04 2010-12-06 Blood collection tube with separation barrier

Country Status (1)

Country Link
WO (1) WO2011069145A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106361354A (en) * 2016-08-31 2017-02-01 秦明 Blood sampling test-tube

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JP5385383B2 (en) 2008-07-21 2014-01-08 ベクトン・ディキンソン・アンド・カンパニー Density phase separator
BR122021008538B1 (en) 2009-05-15 2022-05-24 Becton, Dickinson And Company Separation kit for separating a fluid sample into first and second phases
WO2013025869A1 (en) * 2011-08-17 2013-02-21 Harvest Technologies Corporation Segregation of oils in the fractionation of aspirated adipose tissues
US8864684B2 (en) 2011-10-13 2014-10-21 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9022950B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
WO2014022275A1 (en) 2012-08-01 2014-02-06 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
EP2906269B1 (en) 2012-10-11 2018-01-03 Magnolia Medical Technologies, Inc. System for delivering a fluid to a patient with reduced contamination
CN104955392B (en) 2012-11-30 2018-11-02 木兰医药技术股份有限公司 The transfer device based on syringe for body fluid sampling
US10772548B2 (en) 2012-12-04 2020-09-15 Magnolia Medical Technologies, Inc. Sterile bodily-fluid collection device and methods
JP6335186B2 (en) 2012-12-04 2018-05-30 マグノリア メディカル テクノロジーズ，インコーポレイテッド Sterile fluid collection device
DE102014206526A1 (en) * 2014-04-04 2015-10-08 Robert Bosch Gmbh Valve device and device for handling liquids
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
EP4059426B1 (en) 2015-06-12 2023-12-13 Magnolia Medical Technologies, Inc. Bodily-fluid sampling and transfer device
JP7273807B2 (en) * 2017-06-09 2023-05-15 マグノリア メディカル テクノロジーズ，インコーポレイテッド Fluid control device and method of using same
CN116250868A (en) 2017-09-12 2023-06-13 木兰医药技术股份有限公司 Fluid control device and method of using the same
CN115553822A (en) 2017-12-07 2023-01-03 木兰医药技术股份有限公司 Fluid control device and method of use
US20200229744A1 (en) * 2019-01-18 2020-07-23 Americord Registry Llc Device for the improved collection of cord blood from an umbilical cord
JP2019101046A (en) * 2019-02-07 2019-06-24 ジャパン・メディカル・リーフ株式会社 Blood test container
JP2022523153A (en) 2019-02-08 2022-04-21 マグノリア メディカル テクノロジーズ，インコーポレイテッド Equipment and methods for fluid collection and distribution
EP3938108B1 (en) 2019-03-11 2023-08-02 Magnolia Medical Technologies, Inc. Fluid control devices
DE102019121723A1 (en) * 2019-08-13 2021-02-18 Sarstedt Ag & Co. Kg Separation bodies and methods for separating blood plasma and blood cells
US20210113127A1 (en) * 2019-10-16 2021-04-22 Becton, Dickinson And Company Multi-chamber blood collection device and related systems and methods
AT525541B1 (en) * 2021-11-29 2023-05-15 Greiner Bio One Gmbh Recording device with a septum and method for its production

Citations (2)

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EP1693109A1 (en) * 2005-02-21 2006-08-23 Hexal Ag Container for separating tumor cells
WO2006102431A2 (en) * 2005-03-22 2006-09-28 Filtrona Richmond, Inc. Bonded fiber structures for use in blood separation

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US3997442A (en) 1974-03-18 1976-12-14 Corning Glass Works Method of separating and partitioning differing density phases of a multiphase fluid
US3972812A (en) 1975-05-08 1976-08-03 Becton, Dickinson And Company Blood serum separation filter disc
US4257886A (en) 1979-01-18 1981-03-24 Becton, Dickinson And Company Apparatus for the separation of blood components
EP0039898B1 (en) 1980-05-08 1984-08-22 Terumo Corporation Apparatus for separating blood
JPH02212768A (en) 1989-02-13 1990-08-23 Terumo Corp Blood sampling tube
US6238578B1 (en) 1996-12-09 2001-05-29 Sherwood Services Ag Method for dispensing separator gel in a blood collection tube

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1693109A1 (en) * 2005-02-21 2006-08-23 Hexal Ag Container for separating tumor cells
WO2006102431A2 (en) * 2005-03-22 2006-09-28 Filtrona Richmond, Inc. Bonded fiber structures for use in blood separation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106361354A (en) * 2016-08-31 2017-02-01 秦明 Blood sampling test-tube

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Publication number Publication date
WO2011069145A2 (en) 2011-06-09

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