WO2011051266A1 - Medical implant for treating arthritis in joints of the human or animal body - Google Patents

Medical implant for treating arthritis in joints of the human or animal body Download PDF

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Publication number
WO2011051266A1
WO2011051266A1 PCT/EP2010/066128 EP2010066128W WO2011051266A1 WO 2011051266 A1 WO2011051266 A1 WO 2011051266A1 EP 2010066128 W EP2010066128 W EP 2010066128W WO 2011051266 A1 WO2011051266 A1 WO 2011051266A1
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WO
WIPO (PCT)
Prior art keywords
joint
medical implant
human
joints
animal body
Prior art date
Application number
PCT/EP2010/066128
Other languages
German (de)
French (fr)
Inventor
Georg Gradl
Original Assignee
Universität Rostock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universität Rostock filed Critical Universität Rostock
Publication of WO2011051266A1 publication Critical patent/WO2011051266A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
    • A61B17/7095—Solid vertebral fillers; devices for inserting such fillers the filler comprising unlinked macroscopic particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00876—Material properties magnetic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B2017/567—Joint mechanisms or joint supports in addition to the natural joints and outside the joint gaps

Definitions

  • the invention relates to a medical
  • Implant for the treatment of osteoarthritis in joints of the human or animal body in particular in the knee joint of a patient.
  • the progressive disappearance of hyaline articular cartilage and thus the articulation of inferior articular cartilage or articular bones is a component of
  • arthrosis in the human body. In most cases, arthrosis is asymmetric with preference for the medial or lateral compartment of a joint. This is especially evident on the knee joint. One-sided arthrosis is particularly common if there is a change in the leg axis. A varicose leg axis (O-legs) leads to an increased wear of the inner
  • the change in the leg axis is usually at the level of the tibial plateau (surface of the tibial bone in the
  • the invention is therefore based on the object to provide a medical implant for the treatment of osteoarthritis in joints of the human or animal body, in particular in the knee joint of a patient, with which such complex procedures are avoided.
  • the invention provides two usable in both opposing joint parts
  • Implants in the bones of the two opposing joint parts significantly reduces the operating effort and makes only a much easier intervention
  • the magnetic field strength of the two magnetic bodies is chosen so that it is adapted to the weight of the patient in a knee joint and contributes to a significant pressure or weight relief of the joint or the two joint partners. It will be a good one Shielding strung, inter alia, by counter-magnets, which are facing de hingenkabgewandten side, and through
  • Measures for the isolation of the magnetic body in the bones of the two partners The exact location of the magnetic body in the bone of the two joint partners is determined, for example, by means of the navigation of prostheses.
  • Magnet body formed from permanent magnets. Also, the magnetic body can particularly in vertebrae of the vertebral column from ⁇ in the joint parts and the joint partners
  • FIG. 1 shows a schematic side view of the two articulated bones of a knee joint with the implants inserted in the first embodiment, a schematic illustration of two according to FIG. 1
  • Fig. 1 associated with a knee joint
  • Fig. 1 shows the joint partners here provided at a distance over ⁇ or joint bones 1, 2, 3 of the femur (femur) and the lower leg Bone 4 (tibia) of the knee joint of a human.
  • Bone windows 7, 8 are inserted into both joint bones 1, 2 at a distance from the respectively assigned plateaus 5, 6 in a horizontal orientation, in which magnetic bodies 9, 10 are inserted.
  • the polarity of the magnetic body 9, 10 inserted in a joint formed by the two joint bones 1, 2, here knee joint, is
  • the two magnetic bodies 9, 10 repel each other.
  • the strength of the magnetic force of both magnetic body 9, 10 is chosen so that this the weight of the
  • Both magnetic bodies 9, 10 are formed from permanent or permanent magnets ⁇ . These are magnets made of one piece of magnetizable material, eg. As iron, cobalt, nickel or ferrite, which retains its static magnetic field, without - as in electromagnets - an elek- fresh current flow is needed.
  • Both magnetic bodies 9, 10 are surrounded by an insulation 11, 12, which the metallic magnetic body 9, 10 opposite to the bone material 3, 4 of the patient isolated and which is the joint-repellent side facing.
  • the magnetic body 9, 10 are circular in cross-section, wherein the insulations 11, 12 cup-shaped and with the openings against the joint space
  • Fig. 3 In the second embodiment of the medical implant shown in Fig. 3 are in the vertebral bodies 21 of the spinal column of a patient by means of a needle 22 finest magnetic body 20 injected, consisting of condensed to point clouds, miniaturized point magnets, each of which have the same name and thus repel each other.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Treatment Devices (AREA)
  • Prostheses (AREA)

Abstract

The invention relates to a medical implant for treating arthritis in joints of the human or animal body, in particular in the knee joint of a patient. In order to prevent extensive means for inserting stable plates in the gap of the knee joint, the invention provides two magnet bodies (9, 10; 20) that can be inserted in two opposite joint parts (1, 2), wherein the polarity of the magnetic body (9, 10; 20) associated with a joint is of the same name.

Description

Medizinisches Implantat zur Behandlung der Arthrose in Gelenken des menschlichen oder tierischen Körpers Medical implant for the treatment of osteoarthritis in joints of the human or animal body
Beschreibung description
Die Erfindung bezieht sich auf ein medizinisches The invention relates to a medical
Implantat zur Behandlung der Arthrose in Gelenken des menschlichen oder tierischen Körpers, insbesondere im Kniegelenk eines Patienten. Der progressive Schwund von hyalinem Gelenkknorpel und somit die Artikulation von minderwertigem Gelenkknorpel oder von Gelenkknochen ist ein Bestandteil der  Implant for the treatment of osteoarthritis in joints of the human or animal body, in particular in the knee joint of a patient. The progressive disappearance of hyaline articular cartilage and thus the articulation of inferior articular cartilage or articular bones is a component of
Gelenkarthrose im menschlichen Körper. Meist bildet sich die Arthrose unsymmetrisch unter Bevorzugung des medialen oder lateralen Kompartiments eines Gelenkes. Dies zeigt sich vor allem am Kniegelenk. Besonders häufig sind einseitig betonte Arthrosen, wenn eine Veränderung der Beinachse vorliegt. Eine varische Beinachse (O-Beine) führt zu einer vermehrten Abnutzung des inneren Joint arthrosis in the human body. In most cases, arthrosis is asymmetric with preference for the medial or lateral compartment of a joint. This is especially evident on the knee joint. One-sided arthrosis is particularly common if there is a change in the leg axis. A varicose leg axis (O-legs) leads to an increased wear of the inner
Gelenkspaltes am Kniegelenk. Bei einer valgischen Joint space at the knee joint. At a valgian
Beinachse (X-Beine) wird das äußere Kompartiment stärker belastet. Bei einseitigen Arthrosen werden somit oft Umstellungen der Beinachse vor einer prothetischen  Leg axis (X-legs), the outer compartment is more heavily loaded. In case of unilateral arthrosis often changes of the leg axis before a prosthetic
Versorgung durchgeführt. Damit kann eine Gelenkprothese entweder vermieden oder der prothetische Ersatz hinaus gezögert werden. Care performed. This can either avoid a joint prosthesis or delay the prosthetic replacement.
Die Änderung der Beinachse wird meist auf der Höhe des Tibiaplateaus (Oberfläche des Schienbeinknochens im The change in the leg axis is usually at the level of the tibial plateau (surface of the tibial bone in the
Unterschenkel) vorgenommen. Dabei werden der Tibiakopf osteotomiert und das Plateau der Tibia angehoben bzw. abgesenkt. Der dadurch entstehende Spalt im Knochen muss mit Implantaten stabilisiert werden, wie z. B. stabilen Platten nach WO 2009/052208 A2. Dies erfordert jedoch aufwändige Operationen, welche den Erfolg einer im weiteren Verlauf oft notwendig werdenden Gelenksprothese negativ beeinflussen. Lower leg). The tibial plateau is osteotomized and the plateau of the tibia is raised or lowered. The resulting gap in the bone must be stabilized with implants, such. B. stable plates according to WO 2009/052208 A2. However, this requires complex operations, which is the success of a further course often become necessary joint prosthesis adversely affect.
Der Erfindung liegt von daher die Aufgabe zugrunde, ein medizinisches Implantat zur Behandlung der Arthrose in Gelenken des menschlichen oder tierischen Körpers, insbesondere im Kniegelenk eines Patienten, zu schaffen, mit welchem derartige aufwändige Verfahren vermieden werden . The invention is therefore based on the object to provide a medical implant for the treatment of osteoarthritis in joints of the human or animal body, in particular in the knee joint of a patient, with which such complex procedures are avoided.
Zur Lösung dieser Aufgabe sieht die Erfindung zwei in beide gegenüberliegende Gelenkteile einsetzbare To solve this problem, the invention provides two usable in both opposing joint parts
Magnetkörper vor, wobei die Polarität der einem Gelenk zugeordneten Magnetkörper gleichnamig ist. Damit werden die im Stand der Technik vorbekannten Verfahren des Magnetic body before, wherein the polarity of a joint associated magnetic body is the same name. Thus, the previously known in the prior art method of
Einsetzens von Implantaten in den Gelenkspalt vermieden. Das Einsetzen der erfindungsgemäßen medizinischen  Inserting implants in the joint space avoided. The onset of the medical invention
Implantate in die Knochen der beiden gegenüberstehenden Gelenkteile reduziert den operativen Aufwand erheblich und macht nur einen deutlich einfacheren Eingriff Implants in the bones of the two opposing joint parts significantly reduces the operating effort and makes only a much easier intervention
notwendig, der die Beinachse nicht verändert, aber trotzdem zu einer Entlastung des betroffenen Gelenkareals führt . Erfindungsgemäß werden in beide artikulierende Gelenks¬ teile bzw. -partner knapp unterhalb der Knorpelschicht Magnetkörper eingebracht, die eine gleichsinnige necessary, which does not change the leg axis, but nevertheless leads to a relief of the affected joint area. According to the invention in both articulating joint parts ¬ or -partner introduced just below the cartilage layer magnetic body, the same sense
Polarität aufweisen, da die Polarität der einem Gelenk, bzw. den beiden Gelenkspartnern eines Kniegelenkes zugeordneten Magnetkörper, gleichnamig sein muss. Have polarity, since the polarity of a joint, or the two joint partners of a knee joint associated magnetic body must be the same name.
Die magnetische Feldstärke der beiden Magnetkörper ist so gewählt, dass diese bei einem Kniegelenk dem Gewicht des Patienten angepasst ist und zu einer wesentlichen Druck- bzw. Gewichtsentlastung des Gelenks bzw. der beiden Gelenkspartner beiträgt. Es wird eine gute Abschirmung u. a. durch Gegenmagneten abgestrebt, die de gelenkabgewandten Seite zugekehrt sind, und durch The magnetic field strength of the two magnetic bodies is chosen so that it is adapted to the weight of the patient in a knee joint and contributes to a significant pressure or weight relief of the joint or the two joint partners. It will be a good one Shielding strung, inter alia, by counter-magnets, which are facing de hingenkabgewandten side, and through
Maßnahmen zur Isolierung der Magnetkörper in den Knochen der beiden Gelenkspartner. Die genaue Lokalisierung der Magnetkörper im Knochen der beiden Gelenkspartner wird z B. mit Hilfe der Navigation von Prothesen bestimmt. Measures for the isolation of the magnetic body in the bones of the two partners. The exact location of the magnetic body in the bone of the two joint partners is determined, for example, by means of the navigation of prostheses.
Weitere vorteilhafte Ausführungsformen der Erfindung ergeben sich aus den Unteransprüchen. So sind die Further advantageous embodiments of the invention will become apparent from the dependent claims. So are the
Magnetkörper aus Permanentmagneten gebildet. Auch können die Magnetkörper insbesondere bei Wirbeln der Wirbel¬ säule aus in die Gelenkteile bzw. Gelenkspartner Magnet body formed from permanent magnets. Also, the magnetic body can particularly in vertebrae of the vertebral column from ¬ in the joint parts and the joint partners
injizierbaren, zu Punktwolken verdichtbaren, injectable, compressible to point clouds,
miniaturisierten Punktmagneten gebildet sein. be formed miniaturized point magnets.
Das erfindungsgemäße medizinische Implantat zur The inventive medical implant for
Behandlung der Arthrose in Gelenken des menschliche Körpers, insbesondere im Kniegelenk, ist nachstehend anhand von zwei in den Zeichnungen näher dargestellten Ausführungsformen näher erläutert. Es zeigt: eine prinzipielle Seitenansicht der beiden auf Abstand dargestellten Gelenkknochen eines Kniegelenkes mit den eingesetzten Implantaten in der ersten Ausführungsform, eine Prinzipdarstellung zweier gemäß Treatment of osteoarthritis in joints of the human body, in particular in the knee joint, is explained below with reference to two embodiments shown in more detail in the drawings. FIG. 1 shows a schematic side view of the two articulated bones of a knee joint with the implants inserted in the first embodiment, a schematic illustration of two according to FIG
Fig. 1 einem Kniegelenk zugeordneten  Fig. 1 associated with a knee joint
Implantate und eine Prinzipdarstellung der Anordnung der Implantate in der zweiten Ausführungsform  Implants and a schematic diagram of the arrangement of the implants in the second embodiment
Die Fig. 1 zeigt die hier auf Abstand gegenüber¬ gestellten Gelenkspartner oder Gelenksknochen 1, 2 des Oberschenkelknochens 3 (Femur) und des Unterschenkel- knochens 4 (Tibia) des Kniegelenkes eines Menschen. In beide Gelenksknochen 1, 2 sind im Abstand von den jeweils zugeordneten Plateaus 5, 6 in horizontaler Ausrichtung Knochenfenster 7, 8 eingebracht, in welche Magnetkörper 9, 10 eingesetzt sind. Die Polarität der in einem, aus den beiden Gelenksknochen 1, 2 gebildeten Gelenk, hier Kniegelenk, eingesetzten Magnetkörper 9, 10 ist Fig. 1 shows the joint partners here provided at a distance over ¬ or joint bones 1, 2, 3 of the femur (femur) and the lower leg Bone 4 (tibia) of the knee joint of a human. Bone windows 7, 8 are inserted into both joint bones 1, 2 at a distance from the respectively assigned plateaus 5, 6 in a horizontal orientation, in which magnetic bodies 9, 10 are inserted. The polarity of the magnetic body 9, 10 inserted in a joint formed by the two joint bones 1, 2, here knee joint, is
gleichnamig, d. h. die beiden Magnetkörper 9, 10 stoßen sich ab. Die Stärke der Magnetkraft beider Magnetkörper 9, 10 ist so gewählt, dass diese dem Gewicht des dasof the same name, d. H. the two magnetic bodies 9, 10 repel each other. The strength of the magnetic force of both magnetic body 9, 10 is chosen so that this the weight of the
Kniegelenk aufweisenden Patienten angepasst ist und zu einer wesentlichen Gewichtsent-lastung des Gelenks beiträgt . Beide Magnetkörper 9, 10 sind aus Dauer- oder Permanent¬ magneten gebildet. Dies sind Magnete aus einem Stück eines magnetisierbaren Materials, z. B. Eisen, Kobalt, Nickel oder Ferrit, welches sein statisches Magnetfeld behält, ohne dass - wie bei Elektromagneten - ein elek- frischer Stromfluss benötigt wird. Knee joint-bearing patients and contributes to a significant weight relieving the joint. Both magnetic bodies 9, 10 are formed from permanent or permanent magnets ¬ . These are magnets made of one piece of magnetizable material, eg. As iron, cobalt, nickel or ferrite, which retains its static magnetic field, without - as in electromagnets - an elek- fresh current flow is needed.
Beide Magnetkörper 9, 10 sind von einer Isolierung 11, 12 umgeben, welche die metallischen Magnetkörper 9, 10 gegenüber dem Knochenmaterial 3, 4 des Patienten isoliert und welche der gelenkabweisenden Seite zugekehrt ist.Both magnetic bodies 9, 10 are surrounded by an insulation 11, 12, which the metallic magnetic body 9, 10 opposite to the bone material 3, 4 of the patient isolated and which is the joint-repellent side facing.
Anstelle der Isolierungen 11, 12 können auch GegenmagneteInstead of the insulation 11, 12 can also counter magnets
13 eingesetzt werden. Im Ausführungs-beispiel nach Fig. 2 sind die Magnetkörper 9, 10 im Querschnitt kreisrund ausgebildet, wobei die Isolie-rungen 11, 12 topfförmig ausgebildet und mit den Öffnungen gegen den Gelenkspalt13 are used. In the embodiment of FIG. 2, the magnetic body 9, 10 are circular in cross-section, wherein the insulations 11, 12 cup-shaped and with the openings against the joint space
14 gerichtet sind, in dem die magnetischen Feldlinien 15 wirksam sind. 14 are directed, in which the magnetic field lines 15 are effective.
In der in Fig. 3 dargestellten zweiten Ausführungsform des medizinischen Implantats sind in die Wirbelkörper 21 der Wirbelsäule eines Patienten mittels einer Nadel 22 feinste Magnetkörper 20 injiziert, die aus zu Punktwolken verdichteten, miniaturisierten Punktmagneten bestehen, die jeweils gleichnamig sind und sich somit gegenseitig abstoßen. In the second embodiment of the medical implant shown in Fig. 3 are in the vertebral bodies 21 of the spinal column of a patient by means of a needle 22 finest magnetic body 20 injected, consisting of condensed to point clouds, miniaturized point magnets, each of which have the same name and thus repel each other.

Claims

Patentansprüche claims
Medizinisches Implantat zur Behandlung der Arthrose in Gelenken des menschlichen oder tierischen Medical implant for the treatment of osteoarthritis in joints of the human or animal
Körpers, insbesondere im Kniegelenk eines Patienten, dadurch gekennzeichnet, Body, in particular in the knee joint of a patient, characterized
dass zwei in beide gegenüberliegende Gelenkteile (1, 2) einsetzbare Magnetkörper (9, 10; 20) in that two magnetic bodies (9, 10, 20) which can be used in both opposing joint parts (1, 2)
vorgesehen sind und die Polarität der einem Gelenk zugeordneten Magnetkörper (9, 10, 20) gleichnamig ist . are provided and the polarity of a joint associated magnetic body (9, 10, 20) is the same name.
Medizinisches Implantat nach Anspruch 1, dadurch gekennzeichnet, dass die Magnetkörper (9, 10) aus Permanentmagneten gebildet sind. Medical implant according to claim 1, characterized in that the magnetic bodies (9, 10) are formed from permanent magnets.
Medizinisches Implantat nach Anspruch 1, dadurch gekennzeichnet, dass die Magnetkörper (20) aus in die Gelenkteile injizierbaren, zu Punktwolken verdichtbaren, miniaturisierten Punktmagneten gebildet sind. A medical implant according to claim 1, characterized in that the magnetic bodies (20) can be injected into miniaturized point magnets which can be injected into point-clouds and can be injected into the joint parts.
Medizinisches Implantat nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Magnetkörper (9, 10) gegenüber dem Knochenmaterial (3, 4) eines Medical implant according to claim 1 or 2, characterized in that the magnetic bodies (9, 10) opposite the bone material (3, 4) of a
Patienten durch Isolierungen (11, 12) abgeschirmt sind . Patients are shielded by insulation (11, 12).
Medizinisches Implantat nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Magnetkörper (9, 10) gegenüber dem Knochenmaterial (3, 4) eines Medical implant according to claim 1 or 2, characterized in that the magnetic bodies (9, 10) opposite the bone material (3, 4) of a
Patienten durch Gegenmagnete (13) abgeschirmt sind. Patients are shielded by counter magnets (13).
PCT/EP2010/066128 2009-10-27 2010-10-26 Medical implant for treating arthritis in joints of the human or animal body WO2011051266A1 (en)

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Application Number Priority Date Filing Date Title
DE102009050851.1 2009-10-27
DE102009050851A DE102009050851A1 (en) 2009-10-27 2009-10-27 Medical implant for the treatment of osteoarthritis in joints of the human or animal body

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WO2011051266A1 true WO2011051266A1 (en) 2011-05-05

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595563A (en) * 1995-09-05 1997-01-21 Moisdon; Roger G. F. Method and apparatus for maintaining the position of body parts
US5879386A (en) * 1994-12-13 1999-03-09 Jore; Matthew B. Magnetic prosthetic system
US6387096B1 (en) * 2000-06-13 2002-05-14 Edward R. Hyde, Jr. Magnetic array implant and method of treating adjacent bone portions
US20060085081A1 (en) * 2004-06-07 2006-04-20 Shadduck John H Implants and methods for treating bone
WO2006121652A2 (en) * 2005-05-06 2006-11-16 Hyde Edward Jr Magnetic vector control system for joints
WO2009052208A2 (en) 2007-10-15 2009-04-23 Cragg Andrew H Knee joint prosthesis and hyaluronate compositions and systems useful for osteoarthritis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2611744C2 (en) * 1976-03-19 1982-01-28 Werner Dipl.-Ing. 8000 Muenchen Kraus Device for maintaining the vitality of bone tissue for endoprostheses

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879386A (en) * 1994-12-13 1999-03-09 Jore; Matthew B. Magnetic prosthetic system
US5595563A (en) * 1995-09-05 1997-01-21 Moisdon; Roger G. F. Method and apparatus for maintaining the position of body parts
US6387096B1 (en) * 2000-06-13 2002-05-14 Edward R. Hyde, Jr. Magnetic array implant and method of treating adjacent bone portions
US20060085081A1 (en) * 2004-06-07 2006-04-20 Shadduck John H Implants and methods for treating bone
WO2006121652A2 (en) * 2005-05-06 2006-11-16 Hyde Edward Jr Magnetic vector control system for joints
WO2009052208A2 (en) 2007-10-15 2009-04-23 Cragg Andrew H Knee joint prosthesis and hyaluronate compositions and systems useful for osteoarthritis

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