WO2010143693A1

WO2010143693A1 - Medical device for forming liquid communication path

Info

Publication number: WO2010143693A1
Application number: PCT/JP2010/059860
Authority: WO
Inventors: 石田美希; 宮原英靖
Original assignee: 株式会社ジェイ・エム・エス
Priority date: 2009-06-12
Filing date: 2010-06-10
Publication date: 2010-12-16
Also published as: MX2011013361A; CN102802692A; HK1178471A1; JPWO2010143693A1; CO6430438A2; CN102802692B; KR101292899B1; KR20120032467A; JP5278548B2

Abstract

A medical device for forming a liquid communication path, comprising: joining members (1, 3) for forming the communication flow path between objects to be communicated with each other; and a protective cap (2) having a tubular shape with a closed end, holding a germicide-impregnated member (18) at the deepest end of the protective cap, and capable of being mounted to at least one of the joining members which are being separated from each other. The inner peripheral surface of the protective cap forms a space (19) for surrounding the tip of the joining member, and the dimensional relationship between the joining member and the protective cap is set so that the germicide-impregnated member (18) faces the tip of the joining member with a spacing between the members. A sealing member (8) is mounted to the inner peripheral surface of the opening end of the protective cap or to the outer peripheral surface of that portion of the joining member which corresponds to the opening end of the protective cap, and when the protective cap is in a mounted state, the sealing member is pressed between the outer peripheral surface of the joining member and the inner peripheral surface of the protective cap to form an airtight structure for the space. The mounting of the cap on the joining member effectively sterilizes the tip of the joining member and, in addition, avoids leakage of the germicide due to the contact of the joining member with the germicide-impregnated member.

Description

Medical fluid communication device

The present invention relates to a medical fluid communication device for forming a communication flow path by coupling together coupling members respectively attached to elements to be communicated, such as a connector device for connecting a medical tube, for example. About. In particular, the present invention relates to a liquid communication device including a protective cap that can be attached to at least one of the coupling members separated from each other and has a sterilizing function.

As a medical connector which is an example of a medical fluid communication device, for example, a connector for connecting a patient side transfer tube (extension tube) and a bag containing dialysate when exchanging dialysate for peritoneal dialysis is known. It has been. Peritoneal dialysis (PD) therapy is a therapy in which dialysate is stored in the abdominal cavity through a peritoneal catheter that has been surgically implanted in the abdominal cavity of the patient in advance, and impurities accumulated in the body are filtered using peritoneal capillaries. It is. A patient lives a daily life with a transfer tube (extension tube) used continuously connected to the outside of the peritoneal perfusion catheter. Then, the patient himself connects the dialysate bag to the tip of the transfer tube several times a day to exchange dialysate in the abdominal cavity.

The biggest problem in performing this peritoneal dialysis is that bacteria that accidentally adhere to the air or skin enter the peritoneal cavity together with the dialysate during the dialysate exchange performed several times a day. If bacteria enter the abdominal cavity, the peritoneum may become inflamed and peritonitis may occur.

Therefore, when performing peritoneal dialysis, it is important to reduce bacterial contamination of the connector attached to the tip of the transfer tube for connection to the dialysate bag. When sterilizing an instrument or tissue, a povidone iodine solution is usually used. In that case, a method of applying a solution to an object and causing it to act is common. Therefore, even in the case of the medical connector as described above, the connector provided at the tip of the transfer tube is provided with a porous material such as a sponge impregnated with a bactericidal agent such as povidone iodine (hereinafter referred to as an impregnated member). The tip of the connector has been sterilized by applying a cap (see Patent Documents 1 to 3).

The medical connector device disclosed in Patent Document 2 will be described with reference to the cross-sectional views shown in FIGS. (A) of FIG. 13 shows the bag side connector 110 which is a female connector provided in a dialysate bag. FIG. 14 (b) shows a patient-side connector 130 configured as a male connector. 13B shows a bag-side connector cap 120, and FIG. 14A shows a patient-side connector cap 140. FIG.

The bag-side connector 110 is composed of a double wall of a first annular luer part 111 and a first tip cylindrical part 112, and a first tube connecting part 116 is provided at the base end part 115 of the first annular luer part 111. Is provided. The first tube connection part 116 is connected to a tube 119 connected to the dialysate bag. A concave portion 117 is provided on the outer periphery of the base end portion 115, and a convex portion 118 is provided on the base end of the first tip cylindrical portion 112. The first tip cylindrical portion 112 is fitted to the base end portion 115 and can be rotated independently of the first tube connecting portion 116 and the first annular luer portion 111 via the concave portion 117 and the convex portion 118. Are combined. A female screw 113 is formed on the inner periphery of the first tip cylindrical portion 112. A sealing member 114 made of an elastic material is embedded in the inner peripheral surface near the tip of the first annular luer portion 111.

On the other hand, the patient-side connector 130 includes a distal end cylindrical portion 132, a second annular luer portion 131 formed on the inside thereof, and a proximal end portion 134 having a second tube connection portion 135. The second tube connection part 135 is connected to the tube 136. The proximal end of the distal cylindrical portion 132 is coupled to the proximal end portion 134, and the distal cylindrical portion 132 extends long so as to cover the distal end of the second annular luer portion 131. On the outer periphery of the distal end cylindrical portion 132, a male screw 133 is formed to be screwed with the female screw 113 provided on the inner periphery of the distal end cylindrical portion 112 of the bag side connector. Further, the outer periphery of the second annular luer part 131 can be in fluid-tight contact with a sealing member formed on the inner periphery of the tip end part of the first annular luer part 111 of the bag side connector.

By bringing the bag-side connector and the patient-side connector close to each other and rotating only the distal end cylindrical portion 112 independently, the female screw 113 and the male screw 133 are screwed together without twisting the

tubes

119 and 136. Can be connected.

The patient-side connector cap 140 includes a third inner cylinder 141, a third outer cylinder 142 formed concentrically around the third inner cylinder 141, and a plug 146 fitted to the tip of the third inner cylinder. On the inner periphery of the third outer cylinder 142, an internal thread 143 is formed that engages with the external thread 133 formed on the outer periphery of the distal end cylindrical portion 132 of the patient-side connector. Is provided with a sealing member 145 made of an elastic material. A sterilization pad 144 containing a sterilizing agent is attached to the base end of the third inner cylinder 141.

The stopper 146 is made of an elastic material, and is pressed against the second annular luer part 131 to seal liquid tightly. The sterilization pad 144 sterilizes the distal end cylindrical portion 132 when the patient side connector 130 is screwed to the patient side connector cap 140. The sealing member 145 seals the patient-side connector cap screwed with the patient-side connector so as to protect it from external contamination.

The bag-side connector cap 120 has a fourth tip cylindrical portion 121 and a fourth cap base end portion 123. The fourth tip cylindrical portion 121 is formed with a male screw 122 that is screwed into a female screw 113 formed on the inner periphery of the first tip cylindrical portion 112.

When the injection of dialysate is completed by the connector device configured as described above and the coupling between the patient side connector 130 and the bag side connector 110 is released, a new patient side connector cap 140 is attached to the patient side connector 130 and screwed in. . In this state, the patient-side connector distal end cylindrical portion 132 is pressed by the sterilization pad 144 in the patient-side connector cap 140 and the sterilized state is maintained.

JP 59-500801 A Japanese Patent Laid-Open No. 8-1555025 Japanese Patent Laid-Open No. 8-215311

Conventionally, in a medical field, it is common to sterilize an object to be sterilized by directly contacting the sterilizing agent with the object to be sterilized. Therefore, in the structures described in

Patent Documents

1 and 2, the impregnated member in the cap is always in contact with the tip of the connector. With this structure, the impregnating member is pressed by the tip of the connector, and the bactericidal agent in the impregnating member exudes.

However, with this structure, the sterilizing agent that has exuded enters the internal flow path of the connector / conduit from the tip of the connector, or the sterilizing agent that leaks out leaks to the outside from the joint between the connector and the cap, contaminating the surroundings. There was a risk of problems such as. As a result, the disinfectant may enter the patient through the internal flow path of the transfer tube, which may adversely affect the health of the PD patient.

Also, in the method described in Patent Document 3, it is necessary to press the impregnation member (absorbing material 10) when removing the protective cap and the closing member from the conduit, and the preservative that has oozed out at that time prevents the protective cap and the closing member from There was a risk of leaking from between and contaminating the surroundings.

Such a problem is not limited to a connector for connecting a peritoneal dialysis tube, but is common to a connector used in a place where a liquid flow path needs to be connected, such as an infusion tube. More generally speaking, this is a problem common to medical fluid communication devices for forming a communication flow path by connecting members respectively attached to communication objects. More specifically, this is a problem common to configurations including a protective cap that can be attached to the coupling members separated from each other and has a sterilizing function.

Therefore, the present invention can sufficiently sterilize the distal end portion of the coupling member by attaching a protective cap that holds the sterilizing agent impregnated member in the back, and the distal end portion of the coupling member becomes the sterilizing agent impregnated member. An object of the present invention is to provide a medical fluid communication device capable of avoiding leakage of a bactericide due to contact.

The medical liquid communication device of the present invention has a connecting member that forms a communication flow path between the communication objects by being attached to each other and connected to each other, and a sterilizing agent having a cylindrical shape with one end closed And a protective cap that holds the impregnated member in the innermost portion and can be attached to at least one of the coupling members separated from each other.

In order to solve the above-described problem, in the medical fluid communication device of the present invention, in a state where the protective cap is mounted on the coupling member, an inner peripheral surface of the protective cap surrounds a distal end portion of the coupling member. The dimensional relationship between the coupling member and the protective cap is set so that the disinfectant-impregnated member is opposed to the distal end portion of the coupling member while maintaining a gap, and the opening end portion of the protective cap is formed. A sealing member mounted on an inner peripheral surface of the coupling member or an outer peripheral surface of a portion of the coupling member corresponding to an opening end of the protective cap, and the outer circumferential surface of the coupling member and the protection in a mounted state of the protective cap. The sealing member is pressed between the inner peripheral surfaces of the cap to form an airtight structure of the space.

According to the above configuration, it is possible to obtain a sufficient sterilizing effect even if the sterilizing agent impregnating member and the tip of the coupling member do not contact with each other by attaching the protective cap that holds the sterilizing agent impregnating member in the back. . Moreover, it is possible to avoid leakage of the sterilizing agent due to the tip of the coupling member coming into contact with the sterilizing agent-impregnated member.

FIG. 1A is a perspective view showing a male connector and a protective cap constituting the medical connector device in Embodiment 1 of the present invention in a separated state. FIG. 1B is a perspective view showing a state in which a protective cap is attached to the male connector in the medical connector device. FIG. 2A is a perspective view showing a female connector constituting the medical connector device. 2B is a perspective view showing a state where the male connector of FIG. 1A and the female connector of FIG. 2A are connected. FIG. 3A is a front view of the male connector of FIG. 1A. 3B is a right side view of the male connector of FIG. 3A. 3C is a cross-sectional view of the male connector of FIG. 3A. FIG. 4A is a front view of the protective cap of FIG. 1A. 4B is a right side view of the protective cap of FIG. 4A. 4C is a cross-sectional view taken along line AA in FIG. 4A. 4D is a cross-sectional view taken along line BB in FIG. 4B. FIG. 5A is a cross-sectional view showing the male connector and the protective cap in FIG. 1A. FIG. 5B is a front view showing the male connector and the protective cap in FIG. 1B. 5C is a cross-sectional view showing the internal structure of the male connector and the protective cap of FIG. 5B. 6A is a front view of the female connector of FIG. 2A. 6B is a left side view of the female connector of FIG. 6A. 6C is a right side view of the female connector of FIG. 6A. 6D is a cross-sectional view of the female connector of FIG. 6A. FIG. 7A is a cross-sectional view showing a male connector and a female connector in an exploded state. FIG. 7B is a front view showing the male connector and the female connector in a connected state. FIG. 7C is a cross-sectional view of the male connector and the female connector of FIG. 7B. FIG. 8 is a graph showing experimental results for demonstrating the effect of inhibiting the povidone iodine solution from exuding by the medical connector device according to the first embodiment of the present invention. FIG. 9A is a graph showing experimental results of accelerated storage for demonstrating sterilization ability retention performance by the medical connector device. FIG. 9B is a graph showing experimental results of room temperature storage for demonstrating the bactericidal ability retention performance of the medical connector device. FIG. 10A is a front view showing a connector and a protective cap that constitute the enteral nutrition connector device according to Embodiment 2 of the present invention. FIG. 10B is a cross-sectional view showing the internal structure of the protective cap. FIG. 10C is a front view showing a state where the protective cap is attached to the connector, with only the protective cap shown in cross section. FIG. 11A is a perspective view showing a mixed injection port and a protective cap that constitute the mixed injection port device according to Embodiment 3 of the present invention. FIG. 11B is a cross-sectional view showing the internal structure of the protective cap. FIG. 12 is a perspective view showing another aspect of the mixed injection port. FIG. 13 is a cross-sectional view showing a configuration of a medical connector device of a conventional example. FIG. 14 is a cross-sectional view showing a configuration of a conventional medical connector device.

The medical liquid communication device of the present invention can take the following modes based on the above configuration.

That is, one of the coupling members is a male connector and has a mounting portion connected to one of the communication targets at a rear end thereof, and the other of the coupling members is a female connector and a second connector at a rear end thereof. It can be set as the structure which has a mounting part connected with the said 2 communication object.

The male connector has an inner cylinder whose lumen forms a flow channel for liquid circulation, and an outer cylinder whose inner diameter is larger than the outer diameter of the inner cylinder and is coaxially coupled to the outer side of the inner cylinder, The front end of the inner cylinder is located on the inner side of the front end of the outer cylinder, and the protective cap and the female connector can be attached to the outside of the outer cylinder.

Preferably, the male connector has a sealing valve that shields the lumen at the tip, and the female connector includes an inner cylinder in which the lumen forms a liquid flow path, and an inner diameter of the inner cylinder. An outer cylinder larger than an outer diameter and coaxially coupled to the outer side of the inner cylinder, and the male connector is inserted and connected to the inner side of the outer cylinder, and the male connector and the female connector Are connected, the tip of the inner cylinder of the female connector penetrates the sealing valve to open the flow path.

In this case, a flange that is formed on the inner surface of the male connector and that has an opening smaller than the outer diameter of the sealing valve is preferably provided on the tip side of the sealing valve.

Preferably, the flange is provided with a rib extending toward the distal end side of the male connector.

Further, a configuration may be adopted in which a position restricting portion for restricting the moving position of the male connector toward the inner portion of the protective cap and securing the space is provided inside the protective cap.

The position restricting portion is formed by an annular flange, and a contact portion having an outer diameter larger than the inner diameter of the annular flange is formed on the outer surface of the distal end portion of the male connector, and the male connector and the protective cap Can be configured such that the moving position of the male connector toward the inner part of the protective cap is restricted by the contact between the annular flange and the contact portion.

Further, the male connector and the protective cap are configured to be coupled by screwing, and the deepest position of the male connector and the protective cap that functions as the position restricting portion functions as the male connector. The moving position toward the back in the protective cap can be configured to be regulated.

Further, an inner member can be fitted inside the protective cap, and the disinfectant-impregnated member can be held at the innermost part of the protective cap by the inner member.

Further, the inner member may have a position restricting portion that restricts a moving position of the male connector toward the inner portion of the protective cap to secure the space.

Further, a reduced diameter part having a smaller diameter than the opening side is provided in the innermost part of the protective cap, and the disinfectant-impregnated member is disposed in the reduced diameter part.

In addition, one of the communication objects includes a port of a medical container for injecting a nutrient or the like used for enteral nutrition, and the other includes a tube for connecting the medical container and a patient. It can be set as the structure which is an intestinal nutrition set. In this case, the connector for enteral nutrition provided at the port of the medical container constitutes one of the coupling members, and the connector provided at one end of the nutrition set and connected to the connector for enteral nutrition, It constitutes the other of the coupling members.

One of the coupling members is a mixed injection port, and the mixed injection port includes a pedestal provided for communication, a disc-shaped valve that is supported on the pedestal from the lower surface side and has an insertion hole formed in the center, and A cover having a fitting hole for exposing an upper surface of a central portion of the valve and covering a peripheral edge of the valve from the upper surface side, and the other of the coupling members can be inserted into the mixed injection port, and a lumen thereof is a liquid flow path It can be set as the structure which is the insert which forms. In this case, the protective cap is configured to be attached to the mixed injection port.

Hereinafter, the medical fluid communication device in the embodiment of the present invention will be specifically described with reference to the drawings.

(Embodiment 1)
The medical liquid communication device according to Embodiment 1 of the present invention is an application example of a medical connector device for tube connection in peritoneal dialysis. First, an outline of the medical connector device of the present embodiment will be described with reference to FIGS. 1A to 2B. FIG. 1A is a perspective view showing a male connector 1 and a protective cap 2 constituting the medical connector device in an exploded state. FIG. 1B is a perspective view showing a state where the male connector 1 and the protective cap 2 of FIG. 1A are connected. FIG. 2A is a perspective view showing a female connector 3 constituting the medical connector device. 2B is a perspective view showing a state in which the male connector 1 shown in FIG. 1A and the female connector 3 shown in FIG. 2A are connected.

In this embodiment, the male connector 1 is used as a patient-side connector, and the female connector 3 is used as a bag-side connector provided in a dialysate bag. The male connector 1, the protective cap 2, and the female connector 3 are all made of resin.

As shown in FIG. 1A, the male connector 1 is fitted with a tube 4 connected to a peritoneal catheter implanted in the abdominal cavity of the patient, for example, at the rear end. A grip portion 5 for operating the male connector 1 is provided at the front portion of the tube 4, and the distal end side forms a coupling portion with the protective cap 2 and the female connector 3. The coupling portion includes a cylindrical portion 6 and a tip small-diameter portion 7 formed to have a slightly smaller diameter than the cylindrical portion 6. A thread groove 6 a is formed on the outer peripheral surface of the cylindrical portion 6. A step is formed at the base end of the cylindrical portion 6 by the large-diameter portion 6b, and an elastic ring 8 that functions as a sealing member is mounted in contact with the large-diameter portion 6b.

The protective cap 2 has a substantially cylindrical shape with one end closed, and can be attached to the outer end of the male connector 1 as shown in FIG. 1B. As will be described later with reference to the cross-sectional view, the protective cap 2 holds a disinfectant impregnated member impregnated with a disinfectant (for example, povidone iodine solution) in the innermost part. On the inner peripheral surface of the protective cap 2, an engagement protrusion (described later) for engaging the screw groove 6 a to fix the connection between the male connector 1 and the protective cap 2 when the male connector 1 is mounted. Is provided.

The female connector 3 is connected to a circuit tip of a peritoneal dialysis device such as a twin bag, a Y set, or an APD. As shown in FIG. 2A, the tube 9 is attached to the rear end. A grip portion 10 for operating the female connector 3 is provided at the front portion of the tube 9, and the distal end side forms a coupling portion with the male connector 1. This coupling portion is formed inside the outer cylinder 11. On the inner peripheral surface of the outer cylinder 11, when connected to the male connector 1, there is an engagement protrusion 12 that engages with the thread groove 6 a and fixes the connection between the male connector 1 and the female connector 3. Is provided. The engaging protrusion provided on the inner peripheral surface of the protective cap 2 is the same as the engaging protrusion 12.

As shown in FIG. 2B, the male connector 1 and the female connector 3 are connected and fixed by inserting the male connector 1 into the outer cylinder 11 and screwing the thread groove 6a and the engaging projection 12 together. The When the female connector 3 and the male connector 1 are connected, the

tubes

4 and 9 communicate with each other through a flow path that penetrates the lumens of the

connectors

1 and 3. However, in FIG. 2B, the female connector 3 is depicted as being horizontally reversed with respect to FIG. 2A.

The feature of this embodiment is the configuration related to the combination of the male connector 1 and the protective cap 2 as described below. Accordingly, the structure of the male connector 1 and the protective cap 2 will be described in more detail with reference to FIGS. 3A to 5C. First, the structure of the protective cap 2 will be described.

3A is a front view of the male connector 1 of FIG. 1A, FIG. 3B is a right side view of the male connector 1 of FIG. 3A, and FIG. 3C is a cross-sectional view of the male connector 1 of FIG. As shown in FIG. 3C, the male connector 1 is formed by being divided into a cylindrical portion 6, an inner member 13 attached to the lumen of the cylindrical portion 6, and a grip portion 5 connected to the rear portion of the cylindrical portion 6. Has been. The rear part of the inner member 13 extends inside the grip part 5 to form a tube connection part 13a, to which the tube 4 is connected. Further, the inner cavity of the inner member 13 forms a flow path 13b.

A sealing valve 14 (for example, a rubber slitted septum) is disposed at the distal end of the lumen of the cylindrical portion 6. A flange 15 that forms an opening smaller than the outer shape of the sealing valve 14 is provided on the inner peripheral surface of the tip of the cylindrical portion 6, and the sealing valve 14 is held between the tip of the inner member 13 and the flange 15. The flange 15 is provided with a rib 15a extending to the tip side.

The sealing valve 14 has a function of sealing the flow path of the inner member 13 lumen when the male connector 1 and the female connector 3 are not connected. This prevents bacteria from entering the flow path from the outside of the male connector 1. In addition, the liquid is prevented from leaking from the flexible tube 4 side. Thus, the sealing valve 14 is effective to ensure the sealed state of the flow path of the inner member 13 lumen, but is not essential. Moreover, you may ensure a sealed state with another method.

Further, the flange 15 provided on the inner peripheral surface of the cylindrical portion 6 makes it easy to hold the sealing valve 14 in the flow path, and suppresses the finger contact with the sealing valve 14 from the distal end side of the male connector 1. Effect is obtained. By providing the rib 15a on the flange 15, the effect can be further improved.

4A is a front view of the protective cap 2, FIG. 4B is a right side view of the protective cap 2 of FIG. 4A, FIG. 4C is a cross-sectional view taken along line AA in FIG. 4A, and FIG. 4D is in FIG. It is sectional drawing along the BB line.

As shown in FIGS. 4C and 4D, the protective cap 2 is formed of a substantially cylindrical outer cylinder 16 whose one end is closed, and an inner member 17 fitted into the outer cylinder 16. In the innermost part of the protective cap 2, a reduced diameter portion 16a having a smaller diameter than the opening side is provided, and a disinfectant-impregnated member 18 is disposed in the reduced diameter portion 16a. The disinfectant-impregnated member 18 is held at the innermost portion by the restriction of the inner end portion 17 a of the inner member 17. By providing the reduced diameter portion 16 a and inserting the sterilizing agent impregnated member 18 therein, the sterilizing agent impregnated member 18 is easily held in the protective cap 2. Furthermore, the effect that the disinfectant-impregnated member 18 is difficult to touch the tip of the male connector 1 is also obtained.

An engagement protrusion 17b is formed on the inner peripheral surface of the opening side end of the inner member 17. The connection between the male connector 1 and the protective cap 2 is formed by screwing the thread groove 6a on the outer peripheral surface of the male connector 1 and the engagement protrusion 17b. Further, the deepest position of the connection between the male connector 1 and the protective cap 2 is regulated by this screwing structure. Therefore, when the male connector and the protective cap are connected, the screwing structure functions as a position restricting element that restricts the moving position of the male connector 1 toward the inner part of the protective cap 2.

Further, an annular flange 17c is formed on the inner peripheral surface of the intermediate portion of the inner member 17, and functions as a similar position restricting portion. That is, a contact portion 6b having an outer diameter larger than the inner diameter of the annular flange 17c is formed on the outer surface of the distal end portion of the male connector 1. Therefore, when the protective cap 2 is attached to the male connector 1, the movement position of the male connector 1 is restricted by the contact between the annular flange 17c and the contact portion 6b.

The sterilizing agent-impregnated member 18 can be formed of a material such as a porous body or a fiber body, for example, a sponge. As an example of the sterilizing agent to be impregnated, a sterilizing agent other than the povidone iodine solution may be used, but a povidone iodine solution is desirable in consideration of the influence on the human body.

Next, with reference to FIGS. 5A to 5C, the state and action when the protective cap 2 is attached to the male connector 1 will be described. 5A is a sectional view showing the male connector 1 and the protective cap 2 in the exploded state of FIG. 1A, FIG. 5B is a front view showing the male connector 1 and the protective cap 2 in the combined state of FIG. 1B, and FIG. These are sectional drawings of male connector 1 and protective cap 2 of Drawing 5B.

The protective cap 2 is attached to the male connector 1 when the male connector 1 and the female connector 3 are not connected to protect the connector tip. When mounting, as shown in FIG. 5A, the opening of the protective cap 2 is opposed to the tip of the male connector 1, and the male connector 1 is rotated while being pushed in. Thereby, the protective cap 2 is attached to the tip of the male connector 1 through the engagement between the engaging protrusion 17b provided on the inner surface of the protective cap 2 and the thread groove 6a on the outer peripheral surface of the male connector 1. Fixed.

At that time, as described above, the annular flange 17c formed on the inner peripheral surface of the inner member 17 of the protective cap functions as a position restricting portion, and depends on the deepest position of the male connector 1 and the protective cap 2 to be screwed together. The restriction structure functions as a position restriction part. Thereby, a space 19 is formed between the periphery of the distal end portion of the male connector 1 and the inner surface of the protective cap 2 (see FIG. 5C). By forming this space, the sterilizing agent-impregnated member 18 held in the protective cap 2 is maintained in a state where it is opposed to the front end of the male connector 1 while maintaining a predetermined interval.

Further, the elastic ring 8 is pressed between the outer peripheral surface of the male connector 1 and the inner peripheral surface of the protective cap 3, whereby the airtightness of the space 19 is maintained. Therefore, iodine is sublimated from the sterilizing agent impregnated member 18 impregnated with the povidone iodine solution to fill the space 19, and a sufficient sterilizing effect on the tip of the male connector 1 sealed in the space 19 is obtained. In the above example, the elastic ring 8 is fitted on the male connector 1, but the elastic ring 8 may be fitted inside the protective cap 3 in order to seal the space 19. In short, the elastic ring 8 may be configured to be pressed from both the protective cap 3 and the male connector 1 when the protective cap 3 is attached to the male connector 1.

However, in the case of a connector for a peritoneal dialysis tube, it is preferable that the elastic ring 8 is externally fitted to the patient-side connector. This is because the protective cap and the connector on the dialysate side can be used only once, whereas the connector on the patient side is replaced once every six months, so that the cost of providing the elastic ring 8 can be reduced. This is not the case as long as the tube is for other purposes.

In this way, the sterilizing agent impregnated member 18 is not in direct contact with the tip of the male connector 1, but a predetermined interval is provided between the sterilizing agent impregnated member 18 and the tip of the male connector 1. It was confirmed by the results of experiments described later that a sufficient bactericidal effect was obtained.

Therefore, according to the medical connector device of the present embodiment, the sterilized state of the distal end portion of the male connector can be easily maintained by attaching the protective cap 2 to the distal end side of the male connector 1. In addition, according to the present embodiment, since a predetermined interval is provided between the sterilizing agent impregnated member 18 and the tip of the male connector 1, the sterilizing agent is exuded when the sterilizing agent impregnated member 18 receives a pressing force. Is avoided. Therefore, the sterilizing agent that has exuded enters the internal flow path of the connector / conduit from the tip of the connector, or the exuding sterilizing agent leaks to the outside from the joint between the connector and the cap, thereby contaminating the surroundings. Such inconvenience can be avoided.

Next, the structure and operation of the female connector 3 will be described with reference to FIGS. 6A to 7C. 6A is a front view of the female connector 3 in FIG. 2A, FIG. 6B is a left side view of the female connector 3 in FIG. 6A, FIG. 6C is a right side view thereof, and FIG. 6D is a female connector 3 in FIG. FIG.

The female connector 3 has an inner cylinder 20 whose inner cavity forms a flow channel for liquid circulation, and an outer cylinder 11 whose inner diameter is larger than the outer diameter of the inner cylinder 20 and is coaxially coupled to the outside of the inner cylinder. A gripping portion 10 is formed at the rear end portion of the outer cylinder 11 and is coupled to the central portion of the inner cylinder 20. The outer cylinder 11 is open at the tip side, and an inner member 21 is inserted therein. Engagement protrusions 12 are formed on the inner peripheral surface of the inner member 21. The inner cylinder 20 includes an inner cylinder distal end portion 20 a that extends toward the opening inside the outer cylinder 11, and a tube connection portion 20 b that extends rearward of the outer cylinder 11 and is positioned inside the grip portion 10.

Next, the state and action when the male connector 1 and the female connector 3 are connected will be described with reference to FIGS. 7A to 7C. 7A is a sectional view showing the male connector 1 and the female connector 3 in an exploded state, FIG. 7B is a front view showing the male connector 1 and the female connector 3 in a connected state, and FIG. 2 is a cross-sectional view of the male connector 1 and the female connector 3 of FIG.

When connecting, as shown in FIG. 7A, the front end opening of the female connector 3 is opposed to the front end of the male connector 1, and the male connector 1 is rotated while being pushed in. Thus, the female connector 3 is attached to the tip of the male connector 1 through the engagement between the engagement protrusion 12 provided on the inner surface of the female connector 3 and the thread groove 6a on the outer peripheral surface of the male connector 1. Installed and fixed.

At that time, as the male connector 1 enters the female connector 3, the inner cylinder tip 20 a penetrates the male connector 1 while expanding the slit of the sealing valve 14 attached to the tip of the male connector 1. 1 is reached and the flow path is opened.

Note that the male connector 1 may have other forms for mounting the protective cap 2 as described above or for connection with the female connector 3. That is, the male connector is constituted by an inner cylinder whose inner cavity forms a liquid flow path, and an outer cylinder whose inner diameter is larger than the outer diameter of the inner cylinder and is coaxially coupled to the outer side of the inner cylinder. The tip of the inner cylinder is located on the inner side of the tip of the outer cylinder, and the protective cap and the female connector are attached to the outside of the outer cylinder. According to this configuration, even when the tip of the male connector is accidentally touched, it is possible to avoid touching the inner cylinder through which the liquid flows and to protect the inner cylinder. Since the bacteria attached to the outer cylinder can be sterilized as described above by covering the protective cap, the bacteria do not enter the flow path.

Hereinafter, the results of an experiment for confirming the effects obtained when the protective cap 2 is attached to the male connector 1 in the medical connector device according to the present embodiment will be described. As a result of the experiment, a sealed space 19 is formed between the periphery of the front end of the male connector 1 and the inner surface of the protective cap 2, and the sterilizing agent impregnated member 18 maintains a predetermined interval in the sealed space. It has been demonstrated that a sufficient bactericidal effect can be obtained by maintaining the state facing the tip of the male connector 1. Further, at that time, exudation of the sterilizing agent due to contact between the sterilizing agent-impregnated member 18 and the tip of the male connector 1 is avoided, and the sterilizing agent enters the internal flow path of the connector / conduit from the tip of the connector. It was proved that this can be avoided.

[Experiment 1: Verification of bactericidal activity]
It was verified that the povidone-iodine solution is capable of sterilizing bacteria present at the tip of the male connector 1 by the configuration in which the povidone iodine solution faces the tip of the male connector 1 in a non-contact state.

The experimental method is as follows. First, five bacterial species of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were used as evaluation species. In the case of Staphylococcus spp., Physiological saline to which 0.01% of Tween 80 (PolyoxyethylenebitSorbitan Monoleate) was added was prepared, and in the case of other bacterial species, those dissolved in physiological saline were prepared.

Next, 10 ³ CFU / 20 μL of the bacterial solution was dispensed at the tip of the male connector 1, and after the protective cap 2 was attached, it was allowed to stand for 3 hours at a body temperature of 30-35 ° C. or a low temperature of 10 ° C. Thereafter, the protective cap 2 was removed, and the male connector 1 was placed in 10 mL of a rinse solution (FLUID D-ST solution / BioMerieux), stirred for 30 seconds, and then filtered through a filter having a diameter of 0.45 μm. After repeating this three times, this filter was placed on an SCD agar medium and cultured at 30-35 ° C., and the viable cell count was confirmed.

As Example 1 based on the present embodiment, the fungicide-impregnated member 18 of the protective cap 2 is impregnated with a 10% povidone iodine solution. As Comparative Example 1, the fungicide-impregnated member 18 of the protective cap 2 is povidone-iodine solution. Instead, a material impregnated with physiological saline was used.

The results of the experiment will be described with reference to (Table 1). For Comparative Example 1, no change was observed from the number of bacteria dispensed under either temperature condition, but for Example 1, all the bacterial species could be killed under either condition. . Therefore, even if the povidone iodine solution was not in contact with the tip of the male connector 1, it was confirmed that the bacteria present at the connector tip could be sterilized.

[Experiment 2: Povidone iodine solution contamination test]
After the protective cap 2 was attached and removed, it was confirmed whether or not the povidone iodine solution in the bactericide-impregnated member 18 of the protective cap 2 was mixed into the liquid flow when the connector conduit portion was passed through.

The experimental method is as follows. That is, the protective cap 2 is attached to the tip of the male connector 1 and left for 4 hours, and then the protective cap 2 is removed. After the female connector 3 is connected to the

male connector

1, 20 mL of ultrapure water is passed through the tube. Example 2 was obtained. With respect to this ultrapure water, effective iodine was quantified by a redox titration method using a 0.02N sodium thiosulfate solution as a titrant. The same test was performed on the conventional connector as Comparative Example 2 (all of the conventional products were in contact with the povidone iodine solution).

From FIG. 8 showing the results of the experiment, in Example 2, compared with Comparative Examples 2A to 2D, although the amount of effective iodine in the impregnated member was large, mixing into the liquid passage was not observed. I understand.

From this result, it was confirmed that exudation of the povidone iodine solution in the sterilizing agent impregnating member 18 can be avoided by making the sterilizing agent impregnating member 18 non-contact with the connector.

[Experiment 3: Verification of bactericidal ability retention performance]
The storage period during which bacteria present at the tip of the male connector 1 can be sterilized was confirmed. The experimental method is as follows. That is, the protective cap 2 is attached to the male connector 1, and after accelerated packaging at 40 ° C / 75% RH after packaging in aluminum packaging material, the water content and effective iodine content in the povidone iodine solution important for sterilization performance The change with time was evaluated. The water content was calculated by measuring the difference between the weight before storage and the weight after storage.

For the effective iodine amount, after the protective cap 2 was immersed in 99.5% ethanol overnight, povidone iodine was extracted by thorough washing, and then a redox titration method using a 0.01 M sodium thiosulfate solution as a titrant. Quantitative determination of effective iodine. At this time, a calibration curve of the povidone iodine solution was prepared for each test, and the effective iodine amount of the specimen was calculated thereby. At the same time, the samples were stored in the same manner at room temperature, and the relationship between accelerated storage and storage at room temperature was confirmed from the moisture and effective iodine data.

Moreover, about this, the bactericidal ability test was done by the same test as Experiment 1, and the bactericidal ability retention period was examined. The temperature condition was one condition of 30-35 ° C., and the bacterial species evaluated was one bacterial species of Staphylococcus epidermidis. As Comparative Example 3, a material impregnated with physiological saline instead of the povidone iodine solution impregnated in the impregnated member of the protective cap 2 was used.

The experimental results of accelerated storage are shown in FIG. 9A, and the results of room temperature storage experiments are shown in FIG. 9B. According to the results of this experiment, it can be seen from the comparison between the amount of water and the amount of effective iodine in each storage period that room temperature storage 12M (month) corresponds to accelerated storage 6W (weeks), and room temperature storage 24M corresponds to accelerated storage 12W. . Therefore, it was confirmed that accelerated storage corresponds to a storage period equivalent to eight times storage at room temperature.

The results of the bactericidal activity test are shown in (Table 2). As a result of this test, viable bacteria were observed in the accelerated storage 18W, and in the case of Example 3, it was confirmed that sufficient sterilization ability could be maintained up to the accelerated storage 15W.

From the above results, it can be confirmed that the accelerated storage 15W is comparable to the room temperature storage equivalent to two and a half years, so that the sterilization ability can be maintained for about two and a half years.

[Experiment 4: Verification of relationship between bactericide concentration in closed space and non-contact bactericidal ability]
An experiment was conducted to investigate the change of non-contact sterilization ability due to the concentration of bactericide in a sealed space.

(1) Step 1
First, as a step 1, the following experiment was performed. That is, 10% povidone iodine solution was used as a bactericidal agent (Example 4), 10 ³ CFU S. epidermidis was used as an evaluation bacterial species, and physiological saline was used for comparison with the evaluation bacterial species (Comparative Example). 4).

The sponge was impregnated with 10 μl, 50 μl, 150 μl and 300 μl of povidone iodine solution, respectively. The sponge impregnated with the povidone iodine solution was attached to the plunger gasket of a 5 ml syringe, and the plunger was adjusted so that the space was 630 ml.

20 μl of 10 ³ CFU bacterial solution (diluted with physiological saline supplemented with 0.01% Tween 80) was dispensed on the side opposite the foam (small diameter at the tip of the syringe) and sealed. This was left still at room temperature, and the number of viable bacteria was counted after 1 hour. The results of this experiment are shown in (Table 3).

From this experimental result, the ratio of the povidone iodine solution necessary for killing the bacteria to the enclosed space volume was calculated. When the spatial volume is 630 mm ³ , it can be seen that 10 ³ CFU of S. epidermidis can be killed if 50% or more of 10% povidone iodine solution is present.

(2) Step 2
Next, as a step 2, the following experiment was performed. That is, sponges were impregnated with 10 μl, 50 μl, 150 μl, and 300 μl of povidone iodine solution, respectively. The foam impregnated with the povidone-iodine solution was attached to the plunger gasket of a 5 ml syringe, and the plunger was adjusted so that the space was each evaluation volume. Each evaluation ^volume was ^{^{630mm 3, 378mm 3, 189mm 3}} , 126mm 3.

20 μl of 10 ³ CFU bacterial solution (diluted with physiological saline supplemented with 0.01% Tween 80) was dispensed on the opposite side of the foam (small diameter at the tip of the syringe). After standing at room temperature, the number of viable bacteria was counted at each evaluation time to check the killing completion time. The results are shown in (Table 4). Evaluation time was 0.5 hr and 1 hr.

According to this experimental result, it is found that 10 ³ CFU of S. epidermidis can be killed if a 10% povidone iodine solution is present in an amount of about 8% or more with respect to the space volume.

(Embodiment 2)
The medical liquid communication device according to the second embodiment of the present invention uses a connector device used for enteral nutrition as an application example. With reference to FIG. 10A to FIG. 10B, the configuration of the connector device for enteral nutrition in the present embodiment will be described.

In enteral nutrition, liquids such as nutrients, liquid foods, or drugs are administered through a tube passed from the patient's nasal cavity to the stomach or duodenum. When administering a nutrient or the like, first, the nutrient or the like is injected into a medical container. Next, a connector attached to one end of an injection path set including a tube is connected to a port (liquid passing portion) of the medical container. Further, the medical container is suspended from the hanger with the port to which the injection path set is connected facing downward. With the medical container hung on the hanger, connect the connector attached to the other end of the infusion path set to the connector at the end of the tube attached to the patient. The product is administered to the patient.

FIG. 10A shows the port 23 of the medical container 22 to which the injection channel set is connected. The port 23 includes a tubular portion 24 in which a liquid passage hole for allowing a liquid substance to pass therethrough and a enteral nutrition connector 25 that forms the distal end of the tubular portion 24. The connector 25 is connected to a connector (not shown) at one end of the injection path set by a luer connection method. That is, the connector 25 and the connector attached to one end of the injection path set constitute the medical fluid communication device in the present embodiment.

This enteral feeding connector device further includes a protective cap 26, and the protective cap 26 is attached to the connector 25 when the medical container 22 is not used. The internal structure of the protective cap 26 is shown in FIG. 10B. The protective cap 26 has a cylindrical shape with one end closed, and a disinfectant-impregnated member 27 is held in the innermost part. A sealing member 28 is attached to the inner peripheral surface of the opening end of the protective cap 26.

As shown in FIG. 10C, when the protective cap 26 is attached to the connector 25, the protective cap 26 forms a space 29 surrounding the periphery of the tip of the connector 25, and the sterilizing agent impregnated member 27 maintains a predetermined interval so that the connector 25 Opposite the tip. Further, with the protective cap 26 attached to the connector 25, the sealing member 28 is pressed between the outer peripheral surface of the connector 25 and the inner peripheral surface of the protective cap 26, and an airtight structure of the space 29 is formed.

According to the enteral nutrition connector device of the present embodiment as described above, the sterilized state of the portion can be easily maintained by attaching the protective cap 26 to the distal end portion of the connector 25. In addition, since the predetermined space 29 is provided between the sterilizing agent impregnated member 27 and the distal end of the enteral nutrition connector 25, the sterilizing agent is prevented from exuding due to the pressing force of the sterilizing agent impregnating member 27. Accordingly, it is possible to avoid the inconvenience that the exfoliated sterilizing agent enters the internal flow path of the port 23 from the distal end portion of the connector 25 or the exuded sterilizing agent leaks to the outside and contaminates the surroundings. .

In the above configuration, the protective cap 26 is attached to the enteral nutrition connector 25 provided in the port 23 of the medical container 22, but the protective cap is attached to the connector at the end of the tube attached to the patient. The same effect can also be obtained by configuring as described above.

(Embodiment 3)
The medical liquid communication device in the third embodiment is an application example of a medical mixed injection port device. With reference to FIGS. 11A to 11B, the configuration of the co-injection port apparatus according to the present embodiment will be described.

The medical co-infusion port is used to administer medicinal solution, etc. to the patient, to mix medicinal solution different from the main medicinal solution into the medicinal solution supply channel, or to sample the liquid flowing in the medicinal solution channel, etc. It is done. Therefore, the mixed injection port is configured such that the above operation can be performed by inserting an insert having a sharp tip into an insertion hole formed in the valve.

The mixed injection port 30 shown in FIG. 11A is mounted in the middle of the tube 31 to be communicated. The communication target is not limited to the tube, and may be any other form. A pedestal 32 is provided on the tube 31, and a cover 34 is attached to the pedestal 32. The pedestal 32 and the cover 33 hold a disc-like valve 34 having an insertion hole formed in the center. That is, the valve 34 is supported by the pedestal 32, the cover 33 is in contact with the valve 34, and the valve 34 is sandwiched between the pedestal 32 and the cover 33. The cover 34 has a fitting hole that exposes the upper surface of the central portion of the valve 34 at the central portion. The pedestal 32 has a through hole that communicates with the lumen of the tube 31.

When an insert (not shown) such as a luer that forms the distal end of the syringe is inserted through the valve 34 of the mixed injection port 30, the lumen of the insert communicates with the lumen of the tube 31. Thereby, liquid can be injected and / or collected, and when the lure is removed from the valve 34, the valve 34 closes due to its elasticity. That is, the co-infusion port device composed of the co-infusion port 30 and the insert constitutes the medical liquid communication device in the present embodiment.

The mixed injection port device further includes a protective cap 35, and the protective cap 35 is attached to the mixed injection port 30 when the mixed injection port 30 is not used.

FIG. 11B shows the internal structure of the protective cap 35. The protective cap 35 has a cylindrical shape with one end closed, and a disinfectant-impregnated member 36 is held at the innermost part. A sealing member 37 is attached to the inner peripheral surface of the opening end of the protective cap 35.

When the protective cap 35 is attached to the mixed injection port 30, the protective cap 35 forms a space surrounding the periphery of the upper end of the mixed injection port 30, and the disinfectant impregnating member 36 is opposed to the upper end of the mixed injection port 30 while maintaining a predetermined interval. . Further, the sealing member 37 is pressed between the outer peripheral surface of the mixed injection port 30 and the inner peripheral surface of the protective cap 35 in a state where the protective cap 35 is attached to the mixed injection port 30, thereby forming an airtight structure of the space.

According to the medical mixed injection port device of the present embodiment as described above, the sterilized state of the portion can be easily maintained by attaching the protective cap 35 to the upper end portion of the mixed injection port 30. In addition, since a predetermined space is provided between the sterilizing agent impregnating member 36 and the tip of the co-injecting port 30, exudation of the sterilizing agent due to the pressing force of the sterilizing agent impregnating member 36 is avoided. Therefore, it is possible to avoid the inconvenience that the exfoliated sterilizing agent enters the internal flow path of the tube 31 from the distal end portion of the mixed injection port 30, or the exuded sterilizing agent leaks to the outside and contaminates the surroundings. it can.

FIG. 12 is a perspective view showing a mixed injection port device according to another aspect of the present embodiment. Elements similar to those of the mixed injection port apparatus shown in FIG. 11A are denoted by the same reference numerals, and description thereof will not be repeated. In this embodiment, the mixed injection port 30 is attached to one end of the tube 31. Even in such an embodiment, the same effect as described above can be obtained by using the same protective cap as described above.

According to the medical fluid communication device of the present invention, the distal end portion of the coupling member can be sufficiently sterilized by attaching the protective cap that holds the sterilizing agent-impregnated member in the back, and the distal end of the coupling member Since the leakage of the sterilizing agent due to the contact of the part with the sterilizing agent-impregnated member is avoided, it is useful for a connector device or the like for channel connection in peritoneal dialysis or infusion.

DESCRIPTION OF SYMBOLS 1

Male connector

2, 26, 35 Protective cap 3

Female connector

4, 9, 31

Tube

5, 10 Holding part 6 Cylindrical part

6a Thread groove

6b Contact part 7 Small end diameter part 8

Elastic ring

11, 16

Outer cylinder

12,

17b Engaging projections

13, 17, 21 Inner member 13a Tube connecting portion 13b Flow path 14 Sealing valve 15 Flange 15a Rib 16a Reduced diameter portion 17a Inner end portion

17c Annular flanges

18, 27, 36 Bactericidal agent impregnated

members

19, 29 Space 20 Inner cylinder 20a Inner cylinder tip 20b Tube connection portion 21 Inner member 22 Medical container 23 Port 24 Tubular portion 25

Enteral nutrition connectors

28 and 37 Sealing member 30 Mixed injection port 32 Base 33 Cover 34 Valve

Claims

A coupling member that is mounted on each communication target and coupled to each other to form a communication channel between the communication targets;
A protective cap that has a cylindrical shape with one end closed, holds the disinfectant-impregnated member at the innermost part, and can be attached to at least one of the coupling members in a state separated from each other;
In a state in which the protective cap is mounted on the coupling member, an inner peripheral surface of the protective cap forms a space surrounding a front end portion of the coupling member, and the sterilizing agent-impregnated member maintains a gap so that the coupling member The mutual dimensional relationship between the coupling member and the protective cap is set so as to face the tip portion of
A sealing member mounted on an inner peripheral surface of the opening end portion of the protective cap or an outer peripheral surface of a portion of the coupling member corresponding to the opening end portion of the protective cap; The medical fluid communication device, wherein the sealing member is pressed between an outer peripheral surface of the member and an inner peripheral surface of the protective cap to form an airtight structure of the space.
One of the coupling members is a male connector, and has a mounting portion connected to one of the communication targets at a rear end portion thereof.
The medical fluid communication device according to claim 1, wherein the other of the coupling members is a female connector, and has a mounting portion connected to the second communication target at a rear end portion thereof.
The male connector has an inner cylinder whose lumen forms a flow channel for liquid circulation, and an outer cylinder whose inner diameter is larger than the outer diameter of the inner cylinder and is coaxially coupled to the outer side of the inner cylinder,
The tip of the inner cylinder is located on the inner side of the tip of the outer cylinder,
The medical fluid communication device according to claim 2, wherein the protective cap and the female connector are attached to the outside of the outer cylinder.
The male connector has a sealing valve that shields the lumen at the tip,
The female connector has an inner cylinder whose inner cavity forms a liquid flow path, and an outer cylinder whose inner diameter is larger than the outer diameter of the inner cylinder and is coaxially coupled to the outer side of the inner cylinder. , The male connector is inserted and connected to the inside of the outer cylinder,
The medical fluid communication device according to claim 2, wherein when the male connector and the female connector are connected, a tip of the inner cylinder of the female connector penetrates the sealing valve and a flow path is opened. .
5. The medical fluid communication device according to claim 4, wherein a flange formed on an inner surface of the male connector and having an opening smaller than an outer diameter of the sealing valve is provided on a tip side of the sealing valve.
The medical fluid communication device according to claim 5, wherein the flange is provided with a rib extending toward a distal end side of the male connector.
7. The position restricting portion that secures the space by restricting a movement position of the male connector toward the inner portion of the protective cap in the protective cap, according to any one of claims 2 to 6. The medical fluid communication device described.
The position restricting portion is formed by an annular flange, and a contact portion having an outer diameter larger than the inner diameter of the annular flange is formed on the outer surface of the distal end portion of the male connector.
8. When the male connector and the protective cap are connected, the movement position of the male connector toward the inner portion of the protective cap is restricted by the contact between the annular flange and the contact portion. The medical fluid communication device described.
The male connector and the protective cap are configured to be coupled by screwing,
The deepest position of the said screw connection of the said male connector and the said protective cap functions as the said position control part, The movement position toward the back | inner part in the said protective cap of the said male connector is controlled. Medical fluid communication device.
The medical fluid communication device according to claim 2, wherein an inner member is fitted into the protective cap, and the sterilizing agent-impregnated member is held at the innermost part of the protective cap by the inner member.
The medical fluid communication device according to claim 10, wherein the inner member has a position restricting portion that restricts a moving position of the male connector toward the inner portion of the protective cap to secure the space.
The medical fluid communication according to claim 2, wherein a diameter-reduced portion having a smaller diameter than the opening side is provided at the innermost portion of the protective cap, and the bactericide-impregnated member is disposed in the diameter-reduced portion. apparatus.
One of the communication objects is a port of a medical container for injecting a nutrient used in enteral nutrition, and the other is an enteral nutrition including a tube for connecting the medical container and a patient. Set,
The connector for enteral nutrition provided at the port of the medical container constitutes one of the coupling members,
The medical fluid communication device according to claim 1, wherein a connector provided at one end of the nutrition set and connected to the enteral nutrition connector constitutes the other of the coupling members.
One of the coupling members is a mixed injection port, and the mixed injection port includes a pedestal provided for communication, a disc-like valve supported on the pedestal from the lower surface side and having an insertion hole formed in a central portion thereof, A cover that has a fitting hole that exposes the upper surface of the central portion and covers the periphery of the valve from the upper surface side;
The other of the coupling members is an insert that can be inserted into the co-injection port and the lumen forms a liquid flow path,
The medical fluid communication device according to claim 1, wherein the protective cap is configured to be attached to the mixed injection port.