WO2009108168A3 - Gold nanoparticle glycoconjugates for generating igg specific for the carbohydrate - Google Patents

Gold nanoparticle glycoconjugates for generating igg specific for the carbohydrate Download PDF

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Publication number
WO2009108168A3
WO2009108168A3 PCT/US2008/012692 US2008012692W WO2009108168A3 WO 2009108168 A3 WO2009108168 A3 WO 2009108168A3 US 2008012692 W US2008012692 W US 2008012692W WO 2009108168 A3 WO2009108168 A3 WO 2009108168A3
Authority
WO
WIPO (PCT)
Prior art keywords
gold nanoparticle
glycoconjugates
carbohydrate
igg specific
generating
Prior art date
Application number
PCT/US2008/012692
Other languages
French (fr)
Other versions
WO2009108168A2 (en
Inventor
Daniel C. Stein
Azadeh Kia
Juhee Park
Philip R. Deshong
Original Assignee
Stein Daniel C
Azadeh Kia
Juhee Park
Deshong Philip R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stein Daniel C, Azadeh Kia, Juhee Park, Deshong Philip R filed Critical Stein Daniel C
Publication of WO2009108168A2 publication Critical patent/WO2009108168A2/en
Publication of WO2009108168A3 publication Critical patent/WO2009108168A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A composition can include a gold nanoparticle and a peptide and an oligosaccharide bound to the gold nanoparticle. The oligosaccharide can be an antigen, so that the composition can be used to induce an immunogenic response.
PCT/US2008/012692 2007-11-12 2008-11-12 Gold nanoparticle glycoconjugates for generating igg specific for the carbohydrate WO2009108168A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US98722407P 2007-11-12 2007-11-12
US60/987,224 2007-11-12
US8377308P 2008-07-25 2008-07-25
US61/083,773 2008-07-25

Publications (2)

Publication Number Publication Date
WO2009108168A2 WO2009108168A2 (en) 2009-09-03
WO2009108168A3 true WO2009108168A3 (en) 2009-12-30

Family

ID=41016632

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/012692 WO2009108168A2 (en) 2007-11-12 2008-11-12 Gold nanoparticle glycoconjugates for generating igg specific for the carbohydrate

Country Status (1)

Country Link
WO (1) WO2009108168A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512755B2 (en) 2011-08-15 2013-08-20 The United States Of America, As Represented By The Secretary Of The Navy Compact multifunctional ligand to enhance colloidal stability of nanoparticles
GB201003088D0 (en) * 2010-02-24 2010-04-14 Univ Exeter Method for the preparation of a novel nanoparticle conjugate
CN110935030B (en) * 2019-11-13 2023-01-10 南方科技大学 Gold nanocluster and preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115214A1 (en) * 1998-01-13 2004-06-17 Xin-Xing Gu Lipooligosaccharide-based vaccine for prevention of Moraxella (Branhamella) catarrhalis infections in humans
US20050049197A1 (en) * 1993-09-14 2005-03-03 Epimmune Inc. Induction of immune response against desired determinants
US20050142539A1 (en) * 2002-01-14 2005-06-30 William Herman Targeted ligands
WO2005111196A1 (en) * 2004-05-14 2005-11-24 National Research Council Canada Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates
US20070249063A1 (en) * 2004-08-30 2007-10-25 Deshong Philip R Biosensors

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050049197A1 (en) * 1993-09-14 2005-03-03 Epimmune Inc. Induction of immune response against desired determinants
US20040115214A1 (en) * 1998-01-13 2004-06-17 Xin-Xing Gu Lipooligosaccharide-based vaccine for prevention of Moraxella (Branhamella) catarrhalis infections in humans
US20050142539A1 (en) * 2002-01-14 2005-06-30 William Herman Targeted ligands
WO2005111196A1 (en) * 2004-05-14 2005-11-24 National Research Council Canada Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates
US20070249063A1 (en) * 2004-08-30 2007-10-25 Deshong Philip R Biosensors

Also Published As

Publication number Publication date
WO2009108168A2 (en) 2009-09-03

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