WO2009105245A3 - Systems and methods for detection of changes in blood flow indicative of stroke and other conditions - Google Patents

Systems and methods for detection of changes in blood flow indicative of stroke and other conditions Download PDF

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Publication number
WO2009105245A3
WO2009105245A3 PCT/US2009/001084 US2009001084W WO2009105245A3 WO 2009105245 A3 WO2009105245 A3 WO 2009105245A3 US 2009001084 W US2009001084 W US 2009001084W WO 2009105245 A3 WO2009105245 A3 WO 2009105245A3
Authority
WO
WIPO (PCT)
Prior art keywords
acoustic signals
subject
stroke
systems
methods
Prior art date
Application number
PCT/US2009/001084
Other languages
French (fr)
Other versions
WO2009105245A2 (en
Inventor
Marco Steinberg
Andrew J.M. Kiruluta
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of WO2009105245A2 publication Critical patent/WO2009105245A2/en
Publication of WO2009105245A3 publication Critical patent/WO2009105245A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Dentistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)

Abstract

The present invention relates to systems, articles, and methods for determining whether injury has occurred to a subject, such as to a subject's head. In one embodiment, acoustic signals from various regions of a subject's body (e.g., various regions of the head) are determined and compared. In some cases, the acoustic signals may be compared to determine whether an injury has occurred, for instance, a traumatic brain injury or stroke. The acoustic signals may comprise one or more vibrations, and in some cases, the vibrations that are determined occur at frequencies between about 20 Hz and about 20 kHz, and in certain cases, at frequencies less than 20 Hz. In some embodiments, a plurality of sensors which can determine acoustic signals are employed, for example, attached to a helmet, a strap, or the like. Additionally, in some embodiments, light is directed at a region of a subject (such as the head), and light reflected from the region is determined to determine the acoustic signals that occurs in the region.
PCT/US2009/001084 2008-02-20 2009-02-20 Systems and methods for detection of changes in blood flow indicative of stroke and other conditions WO2009105245A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3011608P 2008-02-20 2008-02-20
US61/030,116 2008-02-20

Publications (2)

Publication Number Publication Date
WO2009105245A2 WO2009105245A2 (en) 2009-08-27
WO2009105245A3 true WO2009105245A3 (en) 2009-11-12

Family

ID=40986107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/001084 WO2009105245A2 (en) 2008-02-20 2009-02-20 Systems and methods for detection of changes in blood flow indicative of stroke and other conditions

Country Status (1)

Country Link
WO (1) WO2009105245A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919144A (en) * 1997-05-06 1999-07-06 Active Signal Technologies, Inc. Apparatus and method for measurement of intracranial pressure with lower frequencies of acoustic signal
US6498942B1 (en) * 1999-08-06 2002-12-24 The University Of Texas System Optoacoustic monitoring of blood oxygenation
US20050015009A1 (en) * 2000-11-28 2005-01-20 Allez Physionix , Inc. Systems and methods for determining intracranial pressure non-invasively and acoustic transducer assemblies for use in such systems
US6887199B2 (en) * 1999-09-23 2005-05-03 Active Signal Technologies, Inc. Brain assessment monitor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919144A (en) * 1997-05-06 1999-07-06 Active Signal Technologies, Inc. Apparatus and method for measurement of intracranial pressure with lower frequencies of acoustic signal
US6498942B1 (en) * 1999-08-06 2002-12-24 The University Of Texas System Optoacoustic monitoring of blood oxygenation
US6887199B2 (en) * 1999-09-23 2005-05-03 Active Signal Technologies, Inc. Brain assessment monitor
US20050015009A1 (en) * 2000-11-28 2005-01-20 Allez Physionix , Inc. Systems and methods for determining intracranial pressure non-invasively and acoustic transducer assemblies for use in such systems

Also Published As

Publication number Publication date
WO2009105245A2 (en) 2009-08-27

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