WO2008127298A3 - Staphylococcal enterotoxin b peptide compositions and methods of use - Google Patents

Staphylococcal enterotoxin b peptide compositions and methods of use Download PDF

Info

Publication number
WO2008127298A3
WO2008127298A3 PCT/US2007/022473 US2007022473W WO2008127298A3 WO 2008127298 A3 WO2008127298 A3 WO 2008127298A3 US 2007022473 W US2007022473 W US 2007022473W WO 2008127298 A3 WO2008127298 A3 WO 2008127298A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
peptide compositions
staphylococcal enterotoxin
peptides
seb
Prior art date
Application number
PCT/US2007/022473
Other languages
French (fr)
Other versions
WO2008127298A2 (en
Inventor
Subroto Chatterjee
Marti Jett
Roger Neill
Original Assignee
Subroto Chatterjee
Marti Jett
Roger Neill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Subroto Chatterjee, Marti Jett, Roger Neill filed Critical Subroto Chatterjee
Publication of WO2008127298A2 publication Critical patent/WO2008127298A2/en
Publication of WO2008127298A3 publication Critical patent/WO2008127298A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/05—Adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/48—Regulators of apoptosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to bacterial peptides, specifically Staphylococcus Enterotoxin B (SEB) peptides that have therapeutic use. The invention further relates to the use of SEB peptides in the diagnosis and therapy of diseases associated with cell proliferation.
PCT/US2007/022473 2006-10-24 2007-10-24 Staphylococcal enterotoxin b peptide compositions and methods of use WO2008127298A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85390606P 2006-10-24 2006-10-24
US60/853,906 2006-10-24

Publications (2)

Publication Number Publication Date
WO2008127298A2 WO2008127298A2 (en) 2008-10-23
WO2008127298A3 true WO2008127298A3 (en) 2009-05-22

Family

ID=39864508

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/022473 WO2008127298A2 (en) 2006-10-24 2007-10-24 Staphylococcal enterotoxin b peptide compositions and methods of use

Country Status (1)

Country Link
WO (1) WO2008127298A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021121277A1 (en) * 2019-12-16 2021-06-24 Tuan Mei Nan A method and composition for treatment of a cancer
JP2024509911A (en) * 2021-03-11 2024-03-05 ザ メソディスト ホスピタル Methods and compositions for the treatment of diseases

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147908A1 (en) * 1996-12-30 2003-08-07 Raymond Kaempfer Broad spectrum antagonists and vaccines directed against pyrogenic exotoxins
US20030152652A1 (en) * 2000-05-05 2003-08-14 Baker John D. Use of echinacea as a hematinic agent
US20030157113A1 (en) * 1999-12-28 2003-08-21 Terman David S. Compositions and methods for treatment of neoplastic disease
US20040072857A1 (en) * 2002-07-02 2004-04-15 Jacob Waugh Polymerized and modified rapamycins and their use in coating medical prostheses
US20050089958A1 (en) * 1996-01-09 2005-04-28 Genentech, Inc. Apo-2 ligand
US20060204565A1 (en) * 2003-05-06 2006-09-14 Low Philip S Conjugates and use thereof
US20060229255A1 (en) * 2003-04-15 2006-10-12 Gema Tarrason Identification of n-alkylglycine trimers for induction of apoptosis

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050089958A1 (en) * 1996-01-09 2005-04-28 Genentech, Inc. Apo-2 ligand
US20030147908A1 (en) * 1996-12-30 2003-08-07 Raymond Kaempfer Broad spectrum antagonists and vaccines directed against pyrogenic exotoxins
US20030157113A1 (en) * 1999-12-28 2003-08-21 Terman David S. Compositions and methods for treatment of neoplastic disease
US20030152652A1 (en) * 2000-05-05 2003-08-14 Baker John D. Use of echinacea as a hematinic agent
US20040072857A1 (en) * 2002-07-02 2004-04-15 Jacob Waugh Polymerized and modified rapamycins and their use in coating medical prostheses
US20060229255A1 (en) * 2003-04-15 2006-10-12 Gema Tarrason Identification of n-alkylglycine trimers for induction of apoptosis
US20060204565A1 (en) * 2003-05-06 2006-09-14 Low Philip S Conjugates and use thereof

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
"Doctoral thesis.", August 2005, PENNSYLVANIA STATE UNIVERSITY. COLLEGE OF AGRICULTURAL SCIENCES., article RAGIN.: "Analysis of T and NKT cell activation and function in resonse to SEB in vivo." *
CHATTERJEE ET AL.: "Digalactosylceramide is the receptor for staphylococcal enterotoxin-B in human kidney proximal tubular cells.", GLYCOBIOLOGY, vol. 5, no. 3, 1995, pages 327 - 333 *
CHATTERJEE ET AL.: "Identification of Staphylococcal enterotoxin B domains involved in binding to cultured human kidney proximal tubular cells: imparting proliferation and death.", EXP BIOL MED, vol. 232, 2007, pages 1142 - 1151 *
HIDA ET AL.: "Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes.", THE JOUMAL OF NEUROSCIENCE, vol. 19, no. 17, 1999, pages 7458 - 7467 *
JETT ET AL.: "Identification of staphylococcal enterotoxin B sequences important for induction of lymphocyte proliferation'' by using synthetic peptide fragments of the toxin.", INFECTION AND IMMUNITY, vol. 62, no. 8, 1994, pages 3408 - 3415 *
JETT ET AL.: "Staphylococcus aureus enterotoxin B challenge of monkeys: correlation of plasma levels of arachidonic acid cascade products with occurrence of illness.", INFECTION AND IMMUNITY, vol. 58, no. 11, 1990, pages 3494 - 3499 *
MEITHKE ET AL.: "T cell-mediated lethal shock triggered in mice by the superantigen Staphylococcal entoerotoxin B: critical role of tumor necrosis factor.", J EXP MED, vol. 175, 1992, pages 91 - 98 *
VAN DER BIJL ET AL.: "Sorting of newly synthesized galactoshpingolipids to the two surface domains I of epithelial cells.", JOUMAL OF CELL BIOLOGY, vol. 132, no. 5, 1996, pages 813 - 821 *

Also Published As

Publication number Publication date
WO2008127298A2 (en) 2008-10-23

Similar Documents

Publication Publication Date Title
PH12019500644A1 (en) Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
WO2010036876A3 (en) Compositions and methods for characterizing and restoring gastrointestinal, skin, and nasal microbiota
WO2008053444A3 (en) Treating a respiratory condition with bifidobacterium
WO2011143624A3 (en) Humanized and chimeric monoclonal antibodies to cd47
WO2007009894A3 (en) Peptides for use in the treatment of obesity
WO2005103084A3 (en) Poly-n-acetyl glucosamine (pnag/dpnag)-binding peptides and methods of use thereof
NZ618571A (en) Peptides and their use
WO2008014200A3 (en) Cyclosporin compositions
WO2008100805A3 (en) Anti-robo4 antibodies and uses therefor
WO2011008092A3 (en) Gram-positive bacteria specific binding compounds
WO2007019865A3 (en) Therapy with cd4 binding peptides and radiation
WO2011048390A3 (en) Gadd45beta targeting agents
NZ598524A (en) Therapeutic dll4 binding proteins
EP3461844A3 (en) Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
WO2009044273A3 (en) Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
WO2007141274A3 (en) Human binding molecules having killing activity against staphylococci and uses thereof
EP2759302A3 (en) 4F-benzoyl-TN14003 combined with rituximab for use in the treatment of a tumour
WO2010132370A3 (en) Soluble tlt-1 for the treatment and diagnosis of sepsis
WO2008036929A3 (en) Complex for transferring an anionic substance into a cell
WO2009099467A3 (en) Cyclosporin compositions
WO2012083302A3 (en) Compositions and methods for the treatment or prevention of human adenovirus-36 infection
WO2008093058A3 (en) Peptides and their use
WO2012014214A3 (en) Peptides derived from plasminogen activator inhibitor-1 (pai-1) for the treatment of hypertension
WO2007144057A3 (en) Antimicrobial carbon
WO2009062576A8 (en) Benzimidazoledihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07873456

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07873456

Country of ref document: EP

Kind code of ref document: A2