WO2008086042A3 - Preventing infection by a measles or respiratory syncytial virus - Google Patents

Preventing infection by a measles or respiratory syncytial virus Download PDF

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Publication number
WO2008086042A3
WO2008086042A3 PCT/US2008/000449 US2008000449W WO2008086042A3 WO 2008086042 A3 WO2008086042 A3 WO 2008086042A3 US 2008000449 W US2008000449 W US 2008000449W WO 2008086042 A3 WO2008086042 A3 WO 2008086042A3
Authority
WO
WIPO (PCT)
Prior art keywords
measles
respiratory syncytial
syncytial virus
preventing infection
methods
Prior art date
Application number
PCT/US2008/000449
Other languages
French (fr)
Other versions
WO2008086042A2 (en
Inventor
Francis V Chisari
Philippe Gallay
Original Assignee
Francis V Chisari
Philippe Gallay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francis V Chisari, Philippe Gallay filed Critical Francis V Chisari
Publication of WO2008086042A2 publication Critical patent/WO2008086042A2/en
Publication of WO2008086042A3 publication Critical patent/WO2008086042A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present application is directed to methods of inhibiting or preventing infection of a mammal by a measles virus and a respiratory syncytial virus, as well as methods of inactivating such viruses.
PCT/US2008/000449 2007-01-10 2008-01-10 Preventing infection by a measles or respiratory syncytial virus WO2008086042A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87972707P 2007-01-10 2007-01-10
US60/879,727 2007-01-10
US96781207P 2007-09-07 2007-09-07
US60/967,812 2007-09-07

Publications (2)

Publication Number Publication Date
WO2008086042A2 WO2008086042A2 (en) 2008-07-17
WO2008086042A3 true WO2008086042A3 (en) 2008-09-18

Family

ID=39609298

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/000449 WO2008086042A2 (en) 2007-01-10 2008-01-10 Preventing infection by a measles or respiratory syncytial virus

Country Status (1)

Country Link
WO (1) WO2008086042A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8728793B2 (en) 2007-07-19 2014-05-20 The Board Of Trustees Of The Leland Stanford Junior University Amphipathic alpha-helical peptide compositions as antiviral agents
US20100204132A1 (en) * 2007-09-11 2010-08-12 Dorian Bevec THERAPEUTIC USES OF PEPTIDES YSAYPDSVPMMS and WMNSTGFTKVCGAPPC
US8722616B2 (en) * 2009-10-22 2014-05-13 Board Of Regents Of The University Of Nebraska Anti-HIV peptides and methods of use thereof
AU2011305652B2 (en) * 2010-09-22 2016-10-20 Janssen Biopharma, Inc. Azido nucleosides and nucleotide analogs
UA117095C2 (en) 2011-12-22 2018-06-25 Аліос Біофарма, Інк. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
KR20180022971A (en) 2015-07-02 2018-03-06 다나-파버 캔서 인스티튜트 인크. The stabilized antimicrobial peptide
AU2017228333C1 (en) 2016-02-29 2022-03-10 Dana-Farber Cancer Institute, Inc. Stapled intracellular-targeting antimicrobial peptides to treat infection
US11325955B2 (en) 2017-07-19 2022-05-10 Dana-Farber Cancer Institute, Inc. Stabilized anti-microbial peptides for the treatment of antibiotic-resistant bacterial infections
EP3539562A1 (en) 2018-03-12 2019-09-18 Eberhard Karls Universität Tübingen Medizinische Fakultät Immunotherapeutic peptides

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOBARDT ET AL.: "Hepatitis C virus NS5A anchor disrupts Human Immunodeficiency virus", vol. 105, no. 14, April 2008 (2008-04-01), pages 5525 - 5530 *
CHENG ET AL.: "A virocidal amphipathic alpha-helical peptide that inhibits Hepatitis C Virus in vitro", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 105, no. 8, February 2008 (2008-02-01), pages 3088 - 3093, XP002531867, DOI: doi:10.1073/PNAS.0712380105 *
ELAZAR ET AL.: "Amphipathic helix-dependent localization of NS5A mediates Hepatitis C Virus RNA replication", JOURNAL OF VIROLOGY, vol. 77, no. 10, May 2003 (2003-05-01), pages 6055 - 6061, XP002531868, DOI: doi:10.1128/JVI.77.10.6055 *
LAMBERT D.M. ET AL.: "Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 93, March 1996 (1996-03-01), pages 2186 - 2191, XP002161016 *
PARTIDOS ET AL.: "Structural requirements for synthetic immunogens to induce measles Virus specific CTL responses", MOLECULAR IMMUNOLOGY, vol. 33, no. 16, 1996, pages 1223 - 1229 *
SHEPERD ET AL.: "Modular alpha-helical mimetics with antiviral activity against Respiratory Syncytial Virus", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128, 2003, pages 13284 - 13289 *
WILD ET AL.: "Inhibition of Measles Virus infection and fusion with peptides corresponding to the leucine zipper region of the fusion protein", JOURNAL OF GENERAL VIROLOGY, vol. 78, 1997, pages 107 - 111, XP002614322 *

Also Published As

Publication number Publication date
WO2008086042A2 (en) 2008-07-17

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