WO2008063521A3 - Gene-based clinical scoring system - Google Patents

Gene-based clinical scoring system Download PDF

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Publication number
WO2008063521A3
WO2008063521A3 PCT/US2007/023917 US2007023917W WO2008063521A3 WO 2008063521 A3 WO2008063521 A3 WO 2008063521A3 US 2007023917 W US2007023917 W US 2007023917W WO 2008063521 A3 WO2008063521 A3 WO 2008063521A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
scoring system
based clinical
clinical scoring
systems
Prior art date
Application number
PCT/US2007/023917
Other languages
French (fr)
Other versions
WO2008063521A2 (en
Inventor
Constance M Elson
Douglas Hayden
David Schoenfeld
Shaw Howland Warren
Ronald G Tompkins
Original Assignee
Gen Hospital Corp
Constance M Elson
Douglas Hayden
David Schoenfeld
Shaw Howland Warren
Ronald G Tompkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp, Constance M Elson, Douglas Hayden, David Schoenfeld, Shaw Howland Warren, Ronald G Tompkins filed Critical Gen Hospital Corp
Publication of WO2008063521A2 publication Critical patent/WO2008063521A2/en
Publication of WO2008063521A3 publication Critical patent/WO2008063521A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression

Abstract

Systems and methods comprising microarray systems to assess prognostic potential in a clinical setting are described.
PCT/US2007/023917 2006-11-13 2007-11-13 Gene-based clinical scoring system WO2008063521A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85861706P 2006-11-13 2006-11-13
US60/858,617 2006-11-13

Publications (2)

Publication Number Publication Date
WO2008063521A2 WO2008063521A2 (en) 2008-05-29
WO2008063521A3 true WO2008063521A3 (en) 2008-10-30

Family

ID=39430318

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/023917 WO2008063521A2 (en) 2006-11-13 2007-11-13 Gene-based clinical scoring system

Country Status (1)

Country Link
WO (1) WO2008063521A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2935712A1 (en) * 2008-09-05 2010-03-12 Ct Hospitalier Regional Univer METHOD FOR DETECTING THE DIFFERENTIAL EXPRESSION OF A MOLECULAR MARK SET ASSOCIATED WITH PARKINSON'S DISEASE
CA2846837A1 (en) * 2011-08-29 2013-03-07 Cardiodx, Inc. Methods and compositions for determining smoking status
KR101504817B1 (en) * 2013-04-05 2015-03-24 연세대학교 산학협력단 Novel system for predicting prognosis of locally advanced gastric cancer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5867795A (en) * 1996-08-23 1999-02-02 Motorola, Inc. Portable electronic device with transceiver and visual image display
US20040209290A1 (en) * 2003-01-15 2004-10-21 Cobleigh Melody A. Gene expression markers for breast cancer prognosis
US20070065846A1 (en) * 2002-03-13 2007-03-22 Baker Joffre B Gene expression profiling in biopsied tumor tissues

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5867795A (en) * 1996-08-23 1999-02-02 Motorola, Inc. Portable electronic device with transceiver and visual image display
US20070065846A1 (en) * 2002-03-13 2007-03-22 Baker Joffre B Gene expression profiling in biopsied tumor tissues
US20040209290A1 (en) * 2003-01-15 2004-10-21 Cobleigh Melody A. Gene expression markers for breast cancer prognosis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
VAN DE VIJVER ET AL.: "A Gene-Expression Signature as a Predictor of Survival in Breast Cancer", THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 347, no. 25, 2002, pages 1999 - 2009, XP008032093 *
VAN 'T VEER ET AL.: "Gene Expression Profiling Predicts Clinical Outcome of Breast Cancer", NATURE, vol. 415, 2002, pages 530 - 536, XP002297133 *

Also Published As

Publication number Publication date
WO2008063521A2 (en) 2008-05-29

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