WO2008028068A3 - NON-HUMAN PRIMATE FCεR1α POLYPEPTIDES - Google Patents

NON-HUMAN PRIMATE FCεR1α POLYPEPTIDES Download PDF

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Publication number
WO2008028068A3
WO2008028068A3 PCT/US2007/077284 US2007077284W WO2008028068A3 WO 2008028068 A3 WO2008028068 A3 WO 2008028068A3 US 2007077284 W US2007077284 W US 2007077284W WO 2008028068 A3 WO2008028068 A3 WO 2008028068A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
human primate
fcεr1α
ige
fcεriα
Prior art date
Application number
PCT/US2007/077284
Other languages
French (fr)
Other versions
WO2008028068A8 (en
WO2008028068A2 (en
Inventor
Gerald R Nakamura
Saloumeh Fischer
Valerie Elizabeth Quarmby
Original Assignee
Genentech Inc
Gerald R Nakamura
Saloumeh Fischer
Valerie Elizabeth Quarmby
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Gerald R Nakamura, Saloumeh Fischer, Valerie Elizabeth Quarmby filed Critical Genentech Inc
Publication of WO2008028068A2 publication Critical patent/WO2008028068A2/en
Publication of WO2008028068A3 publication Critical patent/WO2008028068A3/en
Publication of WO2008028068A8 publication Critical patent/WO2008028068A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Novel non-human primate FcεRIα polypeptides are provided. These receptor polypeptides are useful as agents for binding IgE, for example, in screening assays and in analysis of potency of anti-IgE drugs, and the like.
PCT/US2007/077284 2006-08-30 2007-08-30 NON-HUMAN PRIMATE FCεR1α POLYPEPTIDES WO2008028068A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82402906P 2006-08-30 2006-08-30
US60/824,029 2006-08-30

Publications (3)

Publication Number Publication Date
WO2008028068A2 WO2008028068A2 (en) 2008-03-06
WO2008028068A3 true WO2008028068A3 (en) 2008-12-24
WO2008028068A8 WO2008028068A8 (en) 2009-08-06

Family

ID=39136904

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/077284 WO2008028068A2 (en) 2006-08-30 2007-08-30 NON-HUMAN PRIMATE FCεR1α POLYPEPTIDES

Country Status (1)

Country Link
WO (1) WO2008028068A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2642295C2 (en) * 2009-10-26 2018-01-24 Дженентек, Инк. Analysis of identification of antibodies specific to therapeutic antibodies against ige, and their application in anaphylaxis
TWI691512B (en) 2015-02-20 2020-04-21 日商橘生藥品工業股份有限公司 Fc fusion high affinity IgE receptor alpha chain
KR102038672B1 (en) * 2018-01-08 2019-10-30 (주)지아이이노베이션 PHARMACEUTICAL COMPOSITION COMPRISING RECOMBINANT EXTRACELLULAR DOMAIN OF IgE Fc RECEPTOR SUBUNIT ALPHA
SG11202005858WA (en) 2018-01-08 2020-07-29 Gi Innovation Inc Extracellular domain of alpha subunit of ige fc receptor, pharmaceutical composition comprising same and method for producing same
EP3738599B1 (en) * 2018-01-12 2023-12-27 GI Innovation, Inc. Composition comprising probiotics and polypeptide having binding affinity for ige and use thereof
CN116420679A (en) 2018-03-26 2023-07-14 瑞泽恩制药公司 Humanized rodents for testing therapeutic agents
WO2021006375A1 (en) * 2019-07-08 2021-01-14 (주)지아이이노베이션 Polypeptide dimer containing high amount of sialic acid and including extracellular domain of alpha subunit of ige fc receptor, and pharmaceutical composition containing same
KR102561135B1 (en) * 2019-07-08 2023-07-31 (주)지아이이노베이션 POLYPEPTIDE DIMER COMPRISING EXTRACELLULAR DOMAIN OF ALPHA SUBUNIT OF IgE Fc RECEPTOR WITH HIGH CONTENT OF SIALIC ACID AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020034771A1 (en) * 1996-11-26 2002-03-21 Frank Glenn R. Method to detect IgE
WO2002026781A2 (en) * 2000-09-26 2002-04-04 Genentech, Inc. Ige receptor antagonists
WO2003054213A2 (en) * 2001-12-19 2003-07-03 Genentech, Inc. NON-HUMAN PRIMATE Fc RECEPTORS AND METHODS OF USE
US6602983B1 (en) * 1988-02-24 2003-08-05 The United States Of America As Represented By The Department Of Health And Human Services Polypeptide and DNA sequence corresponding to human receptor with high affinity for IgE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602983B1 (en) * 1988-02-24 2003-08-05 The United States Of America As Represented By The Department Of Health And Human Services Polypeptide and DNA sequence corresponding to human receptor with high affinity for IgE
US20020034771A1 (en) * 1996-11-26 2002-03-21 Frank Glenn R. Method to detect IgE
WO2002026781A2 (en) * 2000-09-26 2002-04-04 Genentech, Inc. Ige receptor antagonists
WO2003054213A2 (en) * 2001-12-19 2003-07-03 Genentech, Inc. NON-HUMAN PRIMATE Fc RECEPTORS AND METHODS OF USE

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SABAN R ET AL: "HUMAN FCERI-IGG AND HUMANIZED ANTI-IGE MONOCLONAL ANTIBODY MAE11 BLOCK PASSIVE SENSITIZATION OF HUMAN AND RHESUS MONKEY LUNG", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY - YEARLY BOOK, INC, US, vol. 94, no. 5, 1 November 1994 (1994-11-01), pages 836 - 843, XP000611550, ISSN: 0091-6749 *
TAKAHASHI K ET AL: "The high affinity IgE receptor (Fc[epsilon]RI) as a target for anti-allergic agents", ALLERGOLOGY INTERNATIONAL 200503 AU, vol. 54, no. 1, March 2005 (2005-03-01), pages 1 - 5, XP009102529, ISSN: 1323-8930 *
TAKAI T ET AL: "Production of humanized antibody against human high-affinity IgE receptor in a serum-free culture of CHO cells and purification of the Fab fragments", BIOSCIENCE BIOTECHNOLOGY BIOCHEMISTRY, JAPAN SOC. FOR BIOSCIENCE, BIOTECHNOLOGY AND AGROCHEM, TOKYO, vol. 65, no. 5, 1 May 2001 (2001-05-01), pages 1082 - 1089, XP002957332, ISSN: 0916-8451 *

Also Published As

Publication number Publication date
WO2008028068A8 (en) 2009-08-06
WO2008028068A2 (en) 2008-03-06

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