WO2007116226A3 - Blood glucose monitoring systems - Google Patents

Blood glucose monitoring systems Download PDF

Info

Publication number
WO2007116226A3
WO2007116226A3 PCT/GB2007/050164 GB2007050164W WO2007116226A3 WO 2007116226 A3 WO2007116226 A3 WO 2007116226A3 GB 2007050164 W GB2007050164 W GB 2007050164W WO 2007116226 A3 WO2007116226 A3 WO 2007116226A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood glucose
glucose measurement
subject
time
glucose monitoring
Prior art date
Application number
PCT/GB2007/050164
Other languages
French (fr)
Other versions
WO2007116226A2 (en
Inventor
Roman Hovorka
Original Assignee
Cambridge Entpr Ltd
Roman Hovorka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Entpr Ltd, Roman Hovorka filed Critical Cambridge Entpr Ltd
Publication of WO2007116226A2 publication Critical patent/WO2007116226A2/en
Publication of WO2007116226A3 publication Critical patent/WO2007116226A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/201Glucose concentration

Abstract

This invention relates to apparatus, methods and computer program code for blood glucose monitoring, more particularly for determining times of blood glucose measurement. An apparatus for determining times of blood glucose measurement of a subject for use in controlling a level of said blood glucose, the apparatus comprising: an input to receive blood glucose measurement data for a series of blood glucose measurements; an adaptive model responsive to said blood glucose measurement data to represent the glucoregulation of said subject; an estimator of a prediction error in said adaptive model as a function of time; and a system to determine a time of a glucose measurement based on a comparison of said time-dependent prediction error with a range of acceptable blood glucose level for said subject.
PCT/GB2007/050164 2006-04-07 2007-03-28 Blood glucose monitoring systems WO2007116226A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0606984A GB2436873A (en) 2006-04-07 2006-04-07 Blood glucose monitoring systems
GB0606984.3 2006-04-07

Publications (2)

Publication Number Publication Date
WO2007116226A2 WO2007116226A2 (en) 2007-10-18
WO2007116226A3 true WO2007116226A3 (en) 2008-03-13

Family

ID=36539491

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/050164 WO2007116226A2 (en) 2006-04-07 2007-03-28 Blood glucose monitoring systems

Country Status (2)

Country Link
GB (1) GB2436873A (en)
WO (1) WO2007116226A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8956291B2 (en) 2005-02-22 2015-02-17 Admetsys Corporation Balanced physiological monitoring and treatment system
GB0719969D0 (en) * 2007-10-12 2007-11-21 Cambridge Entpr Ltd Substance monitoring and control in human or animal bodies
DE502007004737D1 (en) 2007-10-16 2010-09-23 Roche Diagnostics Gmbh Method for storing a measurement series
CN103400028B (en) 2008-04-04 2017-04-12 海吉雅有限公司 Device for optimizing patient's insulin dosage regimen
US9220456B2 (en) 2008-04-04 2015-12-29 Hygieia, Inc. Systems, methods and devices for achieving glycemic balance
US10624577B2 (en) 2008-04-04 2020-04-21 Hygieia, Inc. Systems, devices, and methods for alleviating glucotoxicity and restoring pancreatic beta-cell function in advanced diabetes mellitus
WO2010056718A2 (en) 2008-11-11 2010-05-20 Hygieia, Inc. Apparatus and system for diabetes management
EP2409253B1 (en) 2009-03-16 2018-12-05 Roche Diabetes Care GmbH Method for automated creation of a user-specific measurement data creation regime for non-continuous blood sugar measurement, data processing device and blood sugar measuring device
EP2413781B1 (en) 2009-03-31 2019-07-24 Abbott Diabetes Care Inc. Overnight closed-loop insulin delivery with model predictive control and glucose measurement error model
ATE555721T1 (en) * 2009-04-23 2012-05-15 Hoffmann La Roche METHOD AND DEVICE FOR DETERMINING RECOMMENDATIONS FOR ACTIVE SUBSTANCE DOSAGES BASED ON MEASUREMENT SERIES OF AT LEAST ONE PHYSIOLOGICAL PARAMETERS OF A PATIENT
DE102009024229B3 (en) * 2009-06-08 2010-10-14 Salzsieder, Eckhard, Dipl.-Phys., Dr. rer.nat. Indication device for automatic determination of individual incretin sensitivity indexes of test person during treatment of non-insulin dependent diabetic mellitus, has output module providing data signal as result of simulation strategy
PL2482870T3 (en) 2009-09-29 2018-05-30 Admetsys Corporation System and method for differentiating containers in medication delivery
JP6084568B2 (en) * 2011-09-27 2017-02-22 テルモ株式会社 Analyte monitor system
EP2844134A4 (en) * 2012-04-30 2016-01-06 Mimar Lp Evidence based interactive monitoring device and method
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9233204B2 (en) 2014-01-31 2016-01-12 Aseko, Inc. Insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
EP3050023B1 (en) 2014-10-27 2021-08-25 Aseko, Inc. Subcutaneous outpatient management
CA2993275C (en) 2015-08-20 2022-06-21 Aseko, Inc. Diabetes management therapy advisor
MA45580A (en) 2016-07-08 2019-05-15 Novo Nordisk As BASAL TITRATION WITH ADAPTIVE TARGET GLYCEMIA
MA46048A (en) 2016-08-25 2019-07-03 Novo Nordisk As BEGINNER KIT FOR TITRATION OF BASIC INSULIN
FR3056095B1 (en) * 2016-09-21 2018-10-12 Commissariat A L'energie Atomique Et Aux Energies Alternatives AUTOMATED SYSTEM FOR REGULATING THE GLYCEMIA OF A PATIENT
FR3056094B1 (en) * 2016-09-21 2018-10-12 Commissariat A L'energie Atomique Et Aux Energies Alternatives AUTOMATED SYSTEM FOR REGULATING THE GLYCEMIA OF A PATIENT
CN110012675B (en) 2016-11-29 2024-02-27 诺和诺德股份有限公司 Initial kit for basal rate titration
JP6874155B2 (en) 2017-05-05 2021-05-19 イーライ リリー アンド カンパニー Closed loop control of physiological glucose
FR3069165A1 (en) * 2017-07-21 2019-01-25 Commissariat A L'energie Atomique Et Aux Energies Alternatives AUTOMATED SYSTEM FOR REGULATING THE GLYCEMIA OF A PATIENT
WO2019125932A1 (en) 2017-12-21 2019-06-27 Eli Lilly And Company Closed loop control of physiological glucose
CN109171754B (en) * 2018-07-27 2022-07-05 清华-伯克利深圳学院筹备办公室 Training method and device of blood sugar prediction model, terminal and storage medium
FR3090315B1 (en) * 2018-12-21 2022-12-09 Commissariat Energie Atomique Automated patient blood glucose control system
WO2022011345A1 (en) * 2020-07-10 2022-01-13 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Kits and methods for measuring insulin sensativity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840020A (en) * 1996-02-12 1998-11-24 Nokia Mobile Phones, Ltd. Monitoring method and a monitoring equipment
WO2005041103A2 (en) * 2003-10-29 2005-05-06 Novo Nordisk A/S Medical advisory system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4436094A (en) 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4704029A (en) 1985-12-26 1987-11-03 Research Corporation Blood glucose monitor
EP0831946A4 (en) * 1995-02-07 1999-09-22 Gensia Inc Feedback controlled drug delivery system
FI112545B (en) * 1997-05-30 2003-12-15 Nokia Corp Method and system for predicting the level of a glycosylated hemoglobin component in a patient's blood
US7267665B2 (en) * 1999-06-03 2007-09-11 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US6599281B1 (en) * 2000-05-03 2003-07-29 Aspect Medical Systems, Inc. System and method for adaptive drug delivery
EP1292324A2 (en) 2000-05-05 2003-03-19 Novo Nordisk A/S Critical illness neuropathy
GB0206792D0 (en) * 2002-03-22 2002-05-01 Leuven K U Res & Dev Normoglycemia
EP1575656B1 (en) * 2002-10-11 2009-06-17 Becton, Dickinson and Company Insulin delivery system with sensor
WO2006011869A2 (en) * 2004-06-28 2006-02-02 Paul M Rosman Predictive trement of dysglycemic excursions associated with diabetes mellitus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840020A (en) * 1996-02-12 1998-11-24 Nokia Mobile Phones, Ltd. Monitoring method and a monitoring equipment
WO2005041103A2 (en) * 2003-10-29 2005-05-06 Novo Nordisk A/S Medical advisory system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HANN C E ET AL: "Integral-based parameter identification for long-term dynamic verification of a glucose-insulin system model", COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, ELSEVIER, AMSTERDAM, NL, vol. 77, no. 3, March 2005 (2005-03-01), pages 259 - 270, XP004756474, ISSN: 0169-2607 *
ROMAN HOVORKA ET AL: "Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes; Controlling glucose", PHYSIOLOGICAL MEASUREMENT, INSTITUTE OF PHYSICS PUBLISHING, BRISTOL, GB, vol. 25, no. 4, 1 August 2004 (2004-08-01), pages 905 - 920, XP020074167, ISSN: 0967-3334 *

Also Published As

Publication number Publication date
GB0606984D0 (en) 2006-05-17
GB2436873A (en) 2007-10-10
WO2007116226A2 (en) 2007-10-18

Similar Documents

Publication Publication Date Title
WO2007116226A3 (en) Blood glucose monitoring systems
WO2011073815A3 (en) Copd exacerbation prediction system and method
WO2011028670A3 (en) Additional calibration for analyte monitor
WO2007041443A3 (en) Systems and methods for analysis of healthcare provider performance
WO2007102842A3 (en) Systems and methods for processing analyte sensor data
WO2005106017A3 (en) Method, system and computer program product for evaluating the accuracy of blood glucose monitoring sensors/devices
WO2008114224A3 (en) Method and device for substance measurement
WO2011044286A3 (en) Data analysis expressions
WO2007062423A3 (en) Pluggable heterogeneous reconciliation
WO2009121040A3 (en) Analyte sensor calibration management
WO2011119201A3 (en) Calibration of glucose monitoring sensor and/or insulin delivery system
WO2014066913A3 (en) Health diagnostic systems and methods
WO2012049291A3 (en) Handheld diabetes management device with bolus calculator
WO2008060694A3 (en) System and/or method for determining sufficiency of pseudorange measurements
WO2006088738A3 (en) Application of in-situ plasma measurements to performance and control of a plasma processing system
WO2011130541A3 (en) Measurements of fatigue level using heart rate variability data
WO2009093145A3 (en) System and method of monitoring computer usage
WO2006072416A3 (en) A system for analysing data and for assisting a person in navigating the data
WO2011104616A3 (en) Methods and systems for providing therapeutic guidelines to a person having diabetes
WO2010014458A3 (en) Apparatus for lead length determination
WO2012092455A3 (en) Models for analyzing data from sequencing-by-synthesis operations
WO2007049157A3 (en) Ovulation cycle monitoring and management
WO2009049219A3 (en) Systems, methods and circuits for determining potential battery failure based on a rate of change of internal impedance
WO2010035042A3 (en) Method of testing a pipeline cut
WO2015025187A8 (en) Method and device for improving prediction and detection of change in a physiological condition

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07733587

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07733587

Country of ref document: EP

Kind code of ref document: A2