WO2006054304A3 - Use of lipid conjugates in the treatment of disease - Google Patents
Use of lipid conjugates in the treatment of disease Download PDFInfo
- Publication number
- WO2006054304A3 WO2006054304A3 PCT/IL2005/001225 IL2005001225W WO2006054304A3 WO 2006054304 A3 WO2006054304 A3 WO 2006054304A3 IL 2005001225 W IL2005001225 W IL 2005001225W WO 2006054304 A3 WO2006054304 A3 WO 2006054304A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disease
- lipid
- treatment
- dimer
- oligomer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
- A61K47/544—Phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2007005975A MX2007005975A (en) | 2004-11-17 | 2005-11-17 | Use of lipid conjugates in the treatment of disease. |
AU2005305456A AU2005305456B2 (en) | 2004-11-17 | 2005-11-17 | Use of lipid conjugates in the treatment of disease |
EP05808267A EP1819345A4 (en) | 2004-11-17 | 2005-11-17 | Use of lipid conjugates in the treatment of disease |
CN2005800467713A CN101175499B (en) | 2004-11-17 | 2005-11-17 | Use of lipid conjugates in the treatment of disease |
BRPI0516810-4A BRPI0516810A (en) | 2004-11-17 | 2005-11-17 | use of lipid conjugates in the treatment of diseases |
CA002587883A CA2587883A1 (en) | 2004-11-17 | 2005-11-17 | Use of polymer-lipid conjugates in the prevention and treatment of chronic pulmonary disease, allergic rhinitis and asthma |
EA200701077A EA012138B1 (en) | 2004-11-17 | 2005-11-17 | Use of lipid conjugates in the treatment of diseases |
JP2007542507A JP2008520650A (en) | 2004-11-17 | 2005-11-17 | Use of lipid complexes in disease treatment |
US11/285,375 US8076312B2 (en) | 2000-01-10 | 2005-11-23 | Use of lipid conjugates in the treatment of disease |
IL183227A IL183227A0 (en) | 2004-11-17 | 2007-05-15 | Use of lipid conjugates in the treatment of disease |
IL212215A IL212215A0 (en) | 2004-11-17 | 2011-04-07 | Use of lipid conjugates in the treatment of disease |
IL212214A IL212214A0 (en) | 2004-11-17 | 2011-04-07 | Use of lipid conjugates in the treatment of disease |
US13/283,020 US8859524B2 (en) | 2005-11-17 | 2011-10-27 | Lipid conjugates in the treatment of chronic rhinosinusitis |
US13/316,592 US8906882B2 (en) | 2005-11-17 | 2011-12-12 | Lipid conjugates in the treatment of allergic rhinitis |
US13/788,325 US20140005115A1 (en) | 2005-11-17 | 2013-03-07 | Lipid conjugates in the treatment of bronchitis |
IL229981A IL229981A0 (en) | 2004-11-17 | 2013-12-17 | Use of lipid conjugates in the treatment of disease |
IL229980A IL229980A0 (en) | 2004-11-17 | 2013-12-17 | Use of lipid conjugates in the treatment of disease |
IL229982A IL229982A0 (en) | 2004-11-17 | 2013-12-17 | Use of lipid conjugates in the treatment of disease |
US14/329,191 US20140323434A1 (en) | 2005-11-17 | 2014-07-11 | Lipid conjugates in the treatment of chronic rfhinosinusitis |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/989,607 | 2004-11-17 | ||
US10/989,606 | 2004-11-17 | ||
US10/989,606 US7811999B2 (en) | 2000-01-10 | 2004-11-17 | Use of lipid conjugates in the treatment of diseases |
US10/989,607 US7772196B2 (en) | 2000-01-10 | 2004-11-17 | Use of lipid conjugates in the treatment of diseases |
PCT/US2005/006591 WO2005084307A2 (en) | 2004-03-02 | 2005-03-02 | Use of lipid conjugates in the treatment of disease |
USPCT/US2005/006591 | 2005-03-02 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/463,792 Continuation-In-Part US20090325876A1 (en) | 2000-01-10 | 2009-05-11 | Use of lipid conjugates in the treatment of diseases associated with vasculature |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/756,765 Continuation-In-Part US7034006B2 (en) | 2000-01-10 | 2001-01-10 | Use of lipid conjugates in the treatment of disease |
US11/285,375 Continuation-In-Part US8076312B2 (en) | 2000-01-10 | 2005-11-23 | Use of lipid conjugates in the treatment of disease |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006054304A2 WO2006054304A2 (en) | 2006-05-26 |
WO2006054304A3 true WO2006054304A3 (en) | 2007-01-25 |
Family
ID=39619055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2005/001225 WO2006054304A2 (en) | 2000-01-10 | 2005-11-17 | Use of lipid conjugates in the treatment of disease |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1819345A4 (en) |
JP (2) | JP2008520650A (en) |
CN (1) | CN101175499B (en) |
AU (1) | AU2005305456B2 (en) |
BR (1) | BRPI0516810A (en) |
CA (1) | CA2587883A1 (en) |
EA (1) | EA012138B1 (en) |
IL (3) | IL183227A0 (en) |
MX (1) | MX2007005975A (en) |
WO (1) | WO2006054304A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090325876A1 (en) * | 2004-09-29 | 2009-12-31 | Saul Yedgar | Use of lipid conjugates in the treatment of diseases associated with vasculature |
US20100035843A1 (en) * | 2007-02-12 | 2010-02-11 | The General Hospital Corporation | Methods for attenuating allergen-induced airway hyperreactivity using cd1d dependent antagonists |
EP2429532A4 (en) * | 2009-05-11 | 2015-05-27 | Yissum Res Dev Co | Lipid-polymer conjugates, their preparation and uses thereof |
CA2925546C (en) | 2012-10-29 | 2022-06-14 | The University Of North Carolina At Chapel Hill | Methods and compositions for treating mucosal tissue disorders |
WO2015005459A1 (en) * | 2013-07-10 | 2015-01-15 | 生化学工業株式会社 | Pharmaceutical composition for respiratory administration |
KR20190097022A (en) | 2016-11-17 | 2019-08-20 | 레노비온, 아이엔씨. | Treatment of Respiratory Diseases and Infections with Glutathione Compositions |
CA3082900A1 (en) | 2017-11-17 | 2019-05-23 | Renovion, Inc. | Stable ascorbic acid compositions and methods of using the same |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5064817A (en) * | 1987-10-23 | 1991-11-12 | Yissum Research Development Company Of Hebrew University Of Jerusalem | Phospholipase a2 inhibiting compositions and their use |
US5470578A (en) * | 1992-07-30 | 1995-11-28 | Seikagaku Kogyo Kabushiki Kaisha | Antirheumatic composition |
US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
US6071532A (en) * | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
US6162787A (en) * | 1999-04-02 | 2000-12-19 | Immudyne, Inc. | Methods for treating arthritis using collagen type II, glucosamine chondroitin sulfate, and compositions |
US6180596B1 (en) * | 1995-05-18 | 2001-01-30 | Wisconsin Alumni Research Foundation | Methods of inhibiting phospholipase A2 and phospholipase A2 stimulator activities |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0232013A (en) * | 1988-07-20 | 1990-02-01 | Denki Kagaku Kogyo Kk | Nasal drop |
ES2044781B1 (en) * | 1992-04-14 | 1994-10-01 | Menarini Lab | PROCEDURE FOR THE PREPARATION OF NEW AMIDES WITH PHOSPHOLIPASE A2 INHIBITING ACTION |
WO1996011670A1 (en) * | 1994-10-14 | 1996-04-25 | The Liposome Company, Inc. | Ether lipid liposomes and their therapeutic use |
JPH11147901A (en) * | 1997-11-19 | 1999-06-02 | Maruho Co Ltd | Kallikrein-kinin system inhibitor |
US7141552B2 (en) * | 2000-01-10 | 2006-11-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases |
US7101859B2 (en) * | 2000-01-10 | 2006-09-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases |
EP2845596A3 (en) * | 2000-01-10 | 2015-07-15 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Use of lipid conjugates in the treatment of disease |
-
2005
- 2005-11-17 BR BRPI0516810-4A patent/BRPI0516810A/en not_active Application Discontinuation
- 2005-11-17 EA EA200701077A patent/EA012138B1/en not_active IP Right Cessation
- 2005-11-17 MX MX2007005975A patent/MX2007005975A/en active IP Right Grant
- 2005-11-17 CN CN2005800467713A patent/CN101175499B/en not_active Expired - Fee Related
- 2005-11-17 JP JP2007542507A patent/JP2008520650A/en active Pending
- 2005-11-17 AU AU2005305456A patent/AU2005305456B2/en not_active Ceased
- 2005-11-17 EP EP05808267A patent/EP1819345A4/en not_active Withdrawn
- 2005-11-17 WO PCT/IL2005/001225 patent/WO2006054304A2/en active Application Filing
- 2005-11-17 CA CA002587883A patent/CA2587883A1/en not_active Abandoned
-
2007
- 2007-05-15 IL IL183227A patent/IL183227A0/en unknown
-
2011
- 2011-04-07 IL IL212215A patent/IL212215A0/en unknown
- 2011-04-07 IL IL212214A patent/IL212214A0/en unknown
- 2011-09-13 JP JP2011199088A patent/JP2012001559A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5064817A (en) * | 1987-10-23 | 1991-11-12 | Yissum Research Development Company Of Hebrew University Of Jerusalem | Phospholipase a2 inhibiting compositions and their use |
US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
US5470578A (en) * | 1992-07-30 | 1995-11-28 | Seikagaku Kogyo Kabushiki Kaisha | Antirheumatic composition |
US6180596B1 (en) * | 1995-05-18 | 2001-01-30 | Wisconsin Alumni Research Foundation | Methods of inhibiting phospholipase A2 and phospholipase A2 stimulator activities |
US6071532A (en) * | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
US6162787A (en) * | 1999-04-02 | 2000-12-19 | Immudyne, Inc. | Methods for treating arthritis using collagen type II, glucosamine chondroitin sulfate, and compositions |
Also Published As
Publication number | Publication date |
---|---|
EP1819345A4 (en) | 2012-04-18 |
IL212214A0 (en) | 2011-06-30 |
WO2006054304A2 (en) | 2006-05-26 |
EA200701077A1 (en) | 2008-04-28 |
MX2007005975A (en) | 2007-10-08 |
JP2012001559A (en) | 2012-01-05 |
CN101175499A (en) | 2008-05-07 |
BRPI0516810A (en) | 2008-09-23 |
CA2587883A1 (en) | 2006-05-26 |
JP2008520650A (en) | 2008-06-19 |
IL183227A0 (en) | 2007-08-19 |
AU2005305456B2 (en) | 2011-05-19 |
EP1819345A2 (en) | 2007-08-22 |
EA012138B1 (en) | 2009-08-28 |
IL212215A0 (en) | 2011-06-30 |
AU2005305456A1 (en) | 2006-05-26 |
CN101175499B (en) | 2010-12-22 |
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