WO2006042332A3 - Apparatus and method for a precision flow assay - Google Patents

Apparatus and method for a precision flow assay Download PDF

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Publication number
WO2006042332A3
WO2006042332A3 PCT/US2005/037122 US2005037122W WO2006042332A3 WO 2006042332 A3 WO2006042332 A3 WO 2006042332A3 US 2005037122 W US2005037122 W US 2005037122W WO 2006042332 A3 WO2006042332 A3 WO 2006042332A3
Authority
WO
WIPO (PCT)
Prior art keywords
flow cell
fluid
flow
flow assay
light beam
Prior art date
Application number
PCT/US2005/037122
Other languages
French (fr)
Other versions
WO2006042332A2 (en
Inventor
Thomas R Witty
Robert Case
Scott Castanon
Original Assignee
Fastraq Inc
Thomas R Witty
Robert Case
Scott Castanon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/991,331 external-priority patent/US20060078471A1/en
Priority claimed from US10/990,762 external-priority patent/US20060079003A1/en
Application filed by Fastraq Inc, Thomas R Witty, Robert Case, Scott Castanon filed Critical Fastraq Inc
Priority to EP05811958A priority Critical patent/EP1805501A2/en
Publication of WO2006042332A2 publication Critical patent/WO2006042332A2/en
Publication of WO2006042332A3 publication Critical patent/WO2006042332A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Abstract

An apparatus is provided for testing fluid samples includes a sensor (18), which can be light source (14), directed to a flow cell (12, 50) and a photo sensor for detecting a light beam (17) reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the reflected light beam from the flow cell, thereby monitoring the test process. The flow cell has a flow channel (60) the allows fluid sample to flow at a rate where sufficient incubation of the fluid will occur before the fluid enters an area where analyte levels will be detected.
PCT/US2005/037122 2004-10-12 2005-10-12 Apparatus and method for a precision flow assay WO2006042332A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05811958A EP1805501A2 (en) 2004-10-12 2005-10-12 Apparatus and method for a precision flow assay

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US61827804P 2004-10-12 2004-10-12
US60/618,278 2004-10-12
US10/991,331 US20060078471A1 (en) 2004-10-12 2004-11-16 Apparatus and method for a precision flow assay
US10/991,331 2004-11-16
US10/990,762 US20060079003A1 (en) 2004-10-12 2004-11-16 Apparatus and method for a precision flow assay
US10/990,762 2004-11-16

Publications (2)

Publication Number Publication Date
WO2006042332A2 WO2006042332A2 (en) 2006-04-20
WO2006042332A3 true WO2006042332A3 (en) 2006-09-28

Family

ID=36149045

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/037122 WO2006042332A2 (en) 2004-10-12 2005-10-12 Apparatus and method for a precision flow assay

Country Status (2)

Country Link
EP (1) EP1805501A2 (en)
WO (1) WO2006042332A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9201059B2 (en) 2008-03-14 2015-12-01 Scandinavian Micro Biodevices Aps Microfluidic system and a method of performing a test
US10145842B2 (en) 2012-04-11 2018-12-04 Quidel Cardiovascular Inc. Microfluidic device, system and method
KR102587637B1 (en) * 2014-12-12 2023-10-10 옵코 다이어그노스틱스, 엘엘씨 Fluidic systems comprising an incubation channel, including fluidic systems formed by molding

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436722B1 (en) * 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
US6451619B1 (en) * 1994-06-29 2002-09-17 Inverness Medical Switzerland Gmbh Monitoring methods and devices for use therein
US20030064526A1 (en) * 2001-09-28 2003-04-03 Orasure Technologies, Inc. Sample collector and test device
US20030175993A1 (en) * 1999-09-10 2003-09-18 Anthony Toranto Ketone assay
US20040096980A1 (en) * 2002-03-14 2004-05-20 Harshad Patel Test strip qualification system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451619B1 (en) * 1994-06-29 2002-09-17 Inverness Medical Switzerland Gmbh Monitoring methods and devices for use therein
US20030175993A1 (en) * 1999-09-10 2003-09-18 Anthony Toranto Ketone assay
US6436722B1 (en) * 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
US20030064526A1 (en) * 2001-09-28 2003-04-03 Orasure Technologies, Inc. Sample collector and test device
US20040096980A1 (en) * 2002-03-14 2004-05-20 Harshad Patel Test strip qualification system

Also Published As

Publication number Publication date
EP1805501A2 (en) 2007-07-11
WO2006042332A2 (en) 2006-04-20

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