WO2006024949A3 - Controlled release dosage forms combining immediate release and sustained release of low-solubility drug - Google Patents

Controlled release dosage forms combining immediate release and sustained release of low-solubility drug Download PDF

Info

Publication number
WO2006024949A3
WO2006024949A3 PCT/IB2005/002825 IB2005002825W WO2006024949A3 WO 2006024949 A3 WO2006024949 A3 WO 2006024949A3 IB 2005002825 W IB2005002825 W IB 2005002825W WO 2006024949 A3 WO2006024949 A3 WO 2006024949A3
Authority
WO
WIPO (PCT)
Prior art keywords
release
low
dosage forms
solubility drug
forms combining
Prior art date
Application number
PCT/IB2005/002825
Other languages
French (fr)
Other versions
WO2006024949A2 (en
Inventor
Leah Elizabeth Appel
Dwayne Thomas Friesen
Scott Max Herbig
Avinash Govind Thombre
Original Assignee
Pfizer Prod Inc
Leah Elizabeth Appel
Dwayne Thomas Friesen
Scott Max Herbig
Avinash Govind Thombre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc, Leah Elizabeth Appel, Dwayne Thomas Friesen, Scott Max Herbig, Avinash Govind Thombre filed Critical Pfizer Prod Inc
Priority to BRPI0514416-7A priority Critical patent/BRPI0514416A/en
Priority to CA002578474A priority patent/CA2578474A1/en
Priority to JP2007529035A priority patent/JP2008511609A/en
Priority to EP05782784A priority patent/EP1789022A2/en
Priority to MX2007002375A priority patent/MX2007002375A/en
Publication of WO2006024949A2 publication Critical patent/WO2006024949A2/en
Publication of WO2006024949A3 publication Critical patent/WO2006024949A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates

Abstract

A controlled release dosage form comprises an immediate release portion and an enteric coated sustained release core.
PCT/IB2005/002825 2004-08-31 2005-08-19 Controlled release dosage forms combining immediate release and sustained release of low-solubility drug WO2006024949A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BRPI0514416-7A BRPI0514416A (en) 2004-08-31 2005-08-19 controlled release dosage forms combining immediate release and controlled release of a low solubility drug
CA002578474A CA2578474A1 (en) 2004-08-31 2005-08-19 Controlled release dosage forms combining immediate release and sustained release of low-solubility drug
JP2007529035A JP2008511609A (en) 2004-08-31 2005-08-19 Controlled release dosage forms combining rapid and sustained release of low-solubility drugs
EP05782784A EP1789022A2 (en) 2004-08-31 2005-08-19 Controlled release dosage forms combining immediate release and sustained release of low-solubility drug
MX2007002375A MX2007002375A (en) 2004-08-31 2005-08-19 Controlled release dosage forms combining immediate release and sustained release of low-solubility drug.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60595504P 2004-08-31 2004-08-31
US60/605,955 2004-08-31

Publications (2)

Publication Number Publication Date
WO2006024949A2 WO2006024949A2 (en) 2006-03-09
WO2006024949A3 true WO2006024949A3 (en) 2006-05-04

Family

ID=35746910

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002825 WO2006024949A2 (en) 2004-08-31 2005-08-19 Controlled release dosage forms combining immediate release and sustained release of low-solubility drug

Country Status (6)

Country Link
EP (1) EP1789022A2 (en)
JP (1) JP2008511609A (en)
BR (1) BRPI0514416A (en)
CA (1) CA2578474A1 (en)
MX (1) MX2007002375A (en)
WO (1) WO2006024949A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7842312B2 (en) 2005-12-29 2010-11-30 Cordis Corporation Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
JP5527921B2 (en) * 2006-12-22 2014-06-25 エスエス製薬株式会社 Oral solid composition concealing bitterness
UY34403A (en) 2011-10-21 2013-05-31 Takeda Pharmaceutical SUSTAINED RELEASE PREPARATION
JPWO2014171542A1 (en) * 2013-04-19 2017-02-23 武田薬品工業株式会社 Controlled release formulation
SG11201805810PA (en) * 2015-09-01 2018-08-30 Wellesley Pharmaceuticals Llc Extended, delayed and immediate release formulation method of manufacturing and use thereof
JP7152481B2 (en) 2017-07-10 2022-10-12 ジェル キャップ テクノロジーズ，エルエルシー Dual release capsule dosage form and method, apparatus and system for manufacturing same
GB201719769D0 (en) * 2017-11-28 2018-01-10 Cronin 3D Ltd Analytical device and methods of use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
EP1027887A2 (en) * 1999-02-10 2000-08-16 Pfizer Products Inc. Matrix controlled release device
US20020009494A1 (en) * 1997-08-11 2002-01-24 Curatolo William J. Solid pharmaceutical dispersions with enhanced bioavailability
WO2004037190A2 (en) * 2002-10-25 2004-05-06 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
WO2005020929A2 (en) * 2003-09-02 2005-03-10 Imran Ahmed Sustained release dosage forms of ziprasidone

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US20020009494A1 (en) * 1997-08-11 2002-01-24 Curatolo William J. Solid pharmaceutical dispersions with enhanced bioavailability
EP1027887A2 (en) * 1999-02-10 2000-08-16 Pfizer Products Inc. Matrix controlled release device
WO2004037190A2 (en) * 2002-10-25 2004-05-06 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
WO2005020929A2 (en) * 2003-09-02 2005-03-10 Imran Ahmed Sustained release dosage forms of ziprasidone

Also Published As

Publication number Publication date
WO2006024949A2 (en) 2006-03-09
JP2008511609A (en) 2008-04-17
EP1789022A2 (en) 2007-05-30
MX2007002375A (en) 2007-04-23
BRPI0514416A (en) 2008-06-10
CA2578474A1 (en) 2006-03-09

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