WO2004093569A1 - Topical composition on the basis of honey - Google Patents
Topical composition on the basis of honey Download PDFInfo
- Publication number
- WO2004093569A1 WO2004093569A1 PCT/EG2004/000003 EG2004000003W WO2004093569A1 WO 2004093569 A1 WO2004093569 A1 WO 2004093569A1 EG 2004000003 W EG2004000003 W EG 2004000003W WO 2004093569 A1 WO2004093569 A1 WO 2004093569A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- honey
- wound
- pure
- compound
- fresh
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Definitions
- Honey Compound is an invention in the medical field made mainly of honey with some other additives to act as a potent and safe wound dressing agent with an antimicrobial and wound healing promotion effects, in an optimum wet wound atmosphere
- Excessive fluid loss through the burn wound may also alter the beneficial properties of the applied bee, by causing its rapid dilution and accelerating its washout from the wound surface. It is also well known that within a few hours of application of honey dressing to the wound surface, the dressing will dry off because of evaporative water loss enlianced by body temperature, malcmg subsequent dressing changes difficult and possibly compromising the natural wound healing process.
- Honey compound consists of the following components in this ratio for preparation: -
- the honey compound is prepared by adding the olive oil and sesame oil to the honey with continuous shaking then rice flour and zinc oxide powder are added then olive leaf extract is added with continuous shaking until complete mixing of the compound without heating.
- This invention presents a new compound made mainly of honey with other additives for topical wound management in which all of the beneficial properties of honey were preserved and enlianced and the drawbacks of using honey were obviated through :-
- the oily content of the compound acts as a barrier preventing excessive loss of body fluids and decreasing evaporative wound water loss thus preventing wound desiccation and providing optimal wet atmosphere for wound healing.
- Olive oil contains polyphenolic compounds, which has an antibacterial effect to enhance wound healing.
- Sesame oil has a local anaesthetic effect decreasing local wound pain.
- Zinc Oxide improves the properties of the compound and supplies the wound with Zinc, which is very important trace element for wound healing process.
- Honey compound is a powerful topical cream for bums and wound healing enhancement and it can be used as follows:
- the cream is applied to the bum or wound smface in a 1 mm thickness layer then covered with dressings according to the wounds depth and extent. Wounds dressings are changed when it become soaked or when cream removed that is to keep the wound covered with the cream all the time until woimd healing.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Honey compound is an invention made mainly of pure bee Honey with some additives to be used as Crearn for topical wound management. The additive augments the natural properties of the pure bee honey as an antimicrobial and wound healing promotion agent. Honey compound obviates the drawbacks of using pure bee honey for wounds, like the intense local pain, excessive fluid extravasa.tion through the wound and wound dressings dryness which may compromise the healing process. Bacteriological investigations, laboratory animals' studies confirmed the superior effects of the honey compound as an antibacterial and wound healing promotion agent in comparison to pure bee honey, and other topical wound agents. The components of the honey compound are stable to produce its long lasting beneficial effects over the wounds through out the dressing regimen.
Description
Honey Compound
Technical Fiel ;-
Honey Compound is an invention in the medical field made mainly of honey with some other additives to act as a potent and safe wound dressing agent with an antimicrobial and wound healing promotion effects, in an optimum wet wound atmosphere
Background Arts-
Honey was used in the treatment of wounds and bums by the ancient Egyptians and other civilizations thousands of years ago. Its use has continued in folk medicine until recent years. Many reports have recently been published demonstrating specific and detailed functions of its effective components as regards its antimicrobial and wound- healing promotion effects.
In spite of the high quality of pure bee honey as a topical wound agent, compared with other topical wound agents, its use is not without certain problems that may limit its optimal application, such as the intense local pain that the patient feels soon after its application. This may be intolerable, particularly in children, as also the excessive body fluid loss through the wound due to honey 's high osmolarity. This fluid loss has to be seriously considered because of its haemodynamic impact, especially in patients with major bums and in children.
Excessive fluid loss through the burn wound may also alter the beneficial properties of the applied bee, by causing its rapid dilution and accelerating its washout from the wound surface.
It is also well known that within a few hours of application of honey dressing to the wound surface, the dressing will dry off because of evaporative water loss enlianced by body temperature, malcmg subsequent dressing changes difficult and possibly compromising the natural wound healing process.
There are also available other trials of honey formulas with many draw backs which make its use unsafe and difficult.
Disclosure of Invention :-
In this invention a compound made mainly of pure bee honey with some other additives to improve its properties and to augment its local and systemic beneficial effects obviating the draw backs of its use.
Honey compound consists of the following components in this ratio for preparation: -
* Fresh pure natural unprocessed bee honey 1000 gm * Fresh pure virgin olive oil 100-150 ml
* Fresh pure sesame oil 100-150 ml
* Fresh pure rice flour 140-180 gm
* Zinc oxide powder 60 gm
* Olive leaf extract 10% 10 gm
The honey compound is prepared by adding the olive oil and sesame oil to the honey with continuous shaking then rice flour and zinc oxide powder are added then olive leaf extract is added with continuous shaking until complete mixing of the compound without heating.
It was proved through the bacteriological examinations how potent is the antibacterial and antifungal effects of the honey compound in comparison to a known antibacterial and antifungal ointments and in comparison to the pure bee honey.
It was also proved throug the laboratory animal studies the potent effect of the honey compound to enhance wound healing in comparison to other topical wound agents and to pure bee honey without side effects.
Best Mode for Carrying Out the Invention :-
This invention presents a new compound made mainly of honey with other additives for topical wound management in which all of the beneficial properties of honey were preserved and enlianced and the drawbacks of using honey were obviated through :-
1 - The oily content of the compound acts as a barrier preventing excessive loss of body fluids and decreasing evaporative wound water loss thus preventing wound desiccation and providing optimal wet atmosphere for wound healing. Olive oil contains polyphenolic compounds, which has an antibacterial effect to enhance wound healing.
Sesame oil has a local anaesthetic effect decreasing local wound pain.
2- Rice flour absorbs wound fluids thus keeping undiluted honey covering the wound for longer time.
3- Zinc Oxide improves the properties of the compound and supplies the wound with Zinc, which is very important trace element for wound healing process.
4- Olive leaf extract with its powerful antibacterial, antifungal and antiviral content augments the beneficial effects of the compound without any drawbacks.
Medical Applicability:-
Honey compound is a powerful topical cream for bums and wound healing enhancement and it can be used as follows:
The cream is applied to the bum or wound smface in a 1 mm thickness layer then covered with dressings according to the wounds depth and extent. Wounds dressings are changed when it become soaked or when cream removed that is to keep the wound covered with the cream all the time until woimd healing.
Claims
Claims
- Pure bee honey 1000 gm
Characterized by
The bee honey should be pure fresh monofloral undiluted unprocessed. - Olive Oil 100 - 150 ml
Characterized by
Olive oil should be fresh pure virgin prepared without heating or any other chemical additives, amount adjusted according to the liquidity of honey. - Sesame Oil 100 - 150 ml
Characterized by
Sesame oil should be pure fresh prepared without chemical additives, amount adjusted according to the liquidity of honey. - Rice Flour 140 - 180 gm Rice flow should be fresh and ultrafme as a standard product for nutritional supplement, amount adjusted according to the liquidity of honey. - Zinc Oxide 60 gm
Characterized by Zinc oxide powder as a standard product of the pharmaceutical companies for medical use. - Olive leaf extracts 10%: 10 gm
Characterized by
Olive leaf extract 10% without added sugar, salt, wheat, com, yeast, soy derivatives, colourings, flavorings or preservatives.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EG2003040374 | 2003-04-21 | ||
EG2003040374 | 2003-04-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004093569A1 true WO2004093569A1 (en) | 2004-11-04 |
Family
ID=33305614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EG2004/000003 WO2004093569A1 (en) | 2003-04-21 | 2004-02-11 | Topical composition on the basis of honey |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2004093569A1 (en) |
Cited By (45)
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---|---|---|---|---|
WO2007137881A1 (en) * | 2006-06-01 | 2007-12-06 | Sano Medical Bvba | Wound care treatment product |
US20120141435A1 (en) * | 2009-05-14 | 2012-06-07 | Sanidad Y Residencias 21, S.A. | Use of olive leaf extracts in a pharmaceutical composition for inducing angiogenesis and vasculogenesis |
CN104207277A (en) * | 2014-08-27 | 2014-12-17 | 尹渭元 | Ready-to-drink type olive oil supplement |
WO2015071274A1 (en) * | 2013-11-12 | 2015-05-21 | Tosama Sanitetnega Materiala D.O.O. | Wound healing fluid and wound or skin dressing |
US9125455B2 (en) | 2010-01-21 | 2015-09-08 | Boa Technology Inc. | Guides for lacing systems |
US9248040B2 (en) | 2012-08-31 | 2016-02-02 | Boa Technology Inc. | Motorized tensioning system for medical braces and devices |
USD751281S1 (en) | 2014-08-12 | 2016-03-15 | Boa Technology, Inc. | Footwear tightening reels |
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US9375053B2 (en) | 2012-03-15 | 2016-06-28 | Boa Technology, Inc. | Tightening mechanisms and applications including the same |
US9408437B2 (en) | 2010-04-30 | 2016-08-09 | Boa Technology, Inc. | Reel based lacing system |
US9439477B2 (en) | 2013-01-28 | 2016-09-13 | Boa Technology Inc. | Lace fixation assembly and system |
USD767269S1 (en) | 2014-08-26 | 2016-09-27 | Boa Technology Inc. | Footwear tightening reel |
US9516923B2 (en) | 2012-11-02 | 2016-12-13 | Boa Technology Inc. | Coupling members for closure devices and systems |
US9532626B2 (en) | 2013-04-01 | 2017-01-03 | Boa Technology, Inc. | Methods and devices for retrofitting footwear to include a reel based closure system |
USD776421S1 (en) | 2015-01-16 | 2017-01-17 | Boa Technology, Inc. | In-footwear lace tightening reel |
US9610185B2 (en) | 2013-03-05 | 2017-04-04 | Boa Technology Inc. | Systems, methods, and devices for automatic closure of medical devices |
US9629417B2 (en) | 2013-07-02 | 2017-04-25 | Boa Technology Inc. | Tension limiting mechanisms for closure devices and methods therefor |
US9681705B2 (en) | 2013-09-13 | 2017-06-20 | Boa Technology Inc. | Failure compensating lace tension devices and methods |
US9700101B2 (en) | 2013-09-05 | 2017-07-11 | Boa Technology Inc. | Guides and components for closure systems and methods therefor |
US9706814B2 (en) | 2013-07-10 | 2017-07-18 | Boa Technology Inc. | Closure devices including incremental release mechanisms and methods therefor |
US9737115B2 (en) | 2012-11-06 | 2017-08-22 | Boa Technology Inc. | Devices and methods for adjusting the fit of footwear |
US9743714B2 (en) | 1997-08-22 | 2017-08-29 | Boa Technology Inc. | Reel based closure system |
US9770070B2 (en) | 2013-06-05 | 2017-09-26 | Boa Technology Inc. | Integrated closure device components and methods |
US9867430B2 (en) | 2003-06-12 | 2018-01-16 | Boa Technology Inc. | Reel based closure system |
US9872790B2 (en) | 2013-11-18 | 2018-01-23 | Boa Technology Inc. | Methods and devices for providing automatic closure of prosthetics and orthotics |
US10070695B2 (en) | 2010-04-30 | 2018-09-11 | Boa Technology Inc. | Tightening mechanisms and applications including the same |
US10076160B2 (en) | 2013-06-05 | 2018-09-18 | Boa Technology Inc. | Integrated closure device components and methods |
USD835976S1 (en) | 2014-01-16 | 2018-12-18 | Boa Technology Inc. | Coupling member |
USD835898S1 (en) | 2015-01-16 | 2018-12-18 | Boa Technology Inc. | Footwear lace tightening reel stabilizer |
US10182935B2 (en) | 2014-10-01 | 2019-01-22 | Ossur Hf | Support for articles and methods for using the same |
US10251451B2 (en) | 2013-03-05 | 2019-04-09 | Boa Technology Inc. | Closure devices including incremental release mechanisms and methods therefor |
US10413019B2 (en) | 2011-10-13 | 2019-09-17 | Boa Technology Inc | Reel-based lacing system |
US10492568B2 (en) | 2014-08-28 | 2019-12-03 | Boa Technology Inc. | Devices and methods for tensioning apparel and other items |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4332509A1 (en) * | 1993-09-24 | 1995-03-30 | Reese S Potatoes Tiefkuehlkost | Potato dish |
CN1270834A (en) * | 1999-04-16 | 2000-10-25 | 张国臣 | Wound healing ointment |
US6171604B1 (en) * | 1996-04-12 | 2001-01-09 | Mahmoud A. Mousa | Honey preparations |
WO2001030363A1 (en) * | 1999-10-26 | 2001-05-03 | Vojislav Pavlovic | A procedure for obtaining a zinc oxide containing product for skin-healing, care and protection in children and adults |
FR2810887A1 (en) * | 2000-06-29 | 2002-01-04 | Seporga Lab | Cosmetic or dermatological compositions for use in protecting the skin against solar radiation, chemicals and detergents comprise 0.01 to 10 percent of an extract of olive leaves |
DE20209721U1 (en) * | 2002-06-22 | 2002-10-31 | Eckardt Rainer | Care ointment for the treatment of dry, heavily stressed and radiation-damaged skin |
-
2004
- 2004-02-11 WO PCT/EG2004/000003 patent/WO2004093569A1/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4332509A1 (en) * | 1993-09-24 | 1995-03-30 | Reese S Potatoes Tiefkuehlkost | Potato dish |
US6171604B1 (en) * | 1996-04-12 | 2001-01-09 | Mahmoud A. Mousa | Honey preparations |
CN1270834A (en) * | 1999-04-16 | 2000-10-25 | 张国臣 | Wound healing ointment |
WO2001030363A1 (en) * | 1999-10-26 | 2001-05-03 | Vojislav Pavlovic | A procedure for obtaining a zinc oxide containing product for skin-healing, care and protection in children and adults |
FR2810887A1 (en) * | 2000-06-29 | 2002-01-04 | Seporga Lab | Cosmetic or dermatological compositions for use in protecting the skin against solar radiation, chemicals and detergents comprise 0.01 to 10 percent of an extract of olive leaves |
DE20209721U1 (en) * | 2002-06-22 | 2002-10-31 | Eckardt Rainer | Care ointment for the treatment of dry, heavily stressed and radiation-damaged skin |
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BE1017155A3 (en) * | 2006-06-01 | 2008-03-04 | Sanomedical Bvba | WOUND CARE PRODUCT. |
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CN104207277B (en) * | 2014-08-27 | 2016-06-22 | 尹渭元 | Namely one drinks olive oil supplement |
CN104207277A (en) * | 2014-08-27 | 2014-12-17 | 尹渭元 | Ready-to-drink type olive oil supplement |
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US11304838B2 (en) | 2014-10-01 | 2022-04-19 | Ossur Hf | Support for articles and methods for using the same |
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US11357279B2 (en) | 2017-05-09 | 2022-06-14 | Boa Technology Inc. | Closure components for a helmet layer and methods for installing same |
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US11492228B2 (en) | 2019-05-01 | 2022-11-08 | Boa Technology Inc. | Reel based closure system |
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