WO2004081548A1 - Systeme et procede pour la discrimination d'aerosol organique par la fluorescence en temps differe - Google Patents
Systeme et procede pour la discrimination d'aerosol organique par la fluorescence en temps differe Download PDFInfo
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- WO2004081548A1 WO2004081548A1 PCT/US2004/007214 US2004007214W WO2004081548A1 WO 2004081548 A1 WO2004081548 A1 WO 2004081548A1 US 2004007214 W US2004007214 W US 2004007214W WO 2004081548 A1 WO2004081548 A1 WO 2004081548A1
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- emission
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- fluorescence
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G01N2015/019—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1486—Counting the particles
Abstract
La présente invention a trait à des systèmes et des procédés utilisant des techniques à résolution temporelle pour la déconvolution d'une réponse mesurée pour la caractérisation de la nature de particules. La réponse mesurée est soumise à une déconvolution en une composante de dispersion et une composante de fluorescence. La composante de fluorescence est soumise à une caractérisation supplémentaire en composantes biologique et non biologique. Un vecteur de discrimination est soumis à un mappage pour la caractérisation de la particule.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45332503P | 2003-03-10 | 2003-03-10 | |
| US60/453,325 | 2003-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2004081548A1 true WO2004081548A1 (fr) | 2004-09-23 |
Family
ID=32990755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2004/007214 WO2004081548A1 (fr) | 2003-03-10 | 2004-03-10 | Systeme et procede pour la discrimination d'aerosol organique par la fluorescence en temps differe |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2004081548A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007101932A2 (fr) * | 2006-03-06 | 2007-09-13 | Horiba Abx Sas | Dispositif et procédé de mesure de photoluminescence, d'absorption et de diffraction d'objets microscopiques dans un fluide |
| WO2008091359A2 (fr) * | 2006-07-03 | 2008-07-31 | Ge Homeland Protection Inc. | Procédés et systèmes pour détecter des particules |
| WO2010149391A1 (fr) * | 2009-06-26 | 2010-12-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Tête de mesure de particules, dispositif de mesure de particules et procédé de mesure de particules pour la mesure de la charge en particules de fluides |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5909278A (en) * | 1996-07-29 | 1999-06-01 | The Regents Of The University Of California | Time-resolved fluorescence decay measurements for flowing particles |
| US6137584A (en) * | 1996-11-27 | 2000-10-24 | Max-Planck-Gesellschaft Zur | Method and device for determining predetermined properties of target particles of a sample medium |
| DE19949658A1 (de) * | 1999-10-14 | 2001-05-10 | Deutsches Krebsforsch | Verfahren und Vorrichtung zur Messung von Fluoreszenz-Kreuzkorrelationen |
| US20020063863A1 (en) * | 2000-02-10 | 2002-05-30 | Peet Kask | Fluorescence intensity and lifetime distribution analysis |
-
2004
- 2004-03-10 WO PCT/US2004/007214 patent/WO2004081548A1/fr active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5909278A (en) * | 1996-07-29 | 1999-06-01 | The Regents Of The University Of California | Time-resolved fluorescence decay measurements for flowing particles |
| US6137584A (en) * | 1996-11-27 | 2000-10-24 | Max-Planck-Gesellschaft Zur | Method and device for determining predetermined properties of target particles of a sample medium |
| DE19949658A1 (de) * | 1999-10-14 | 2001-05-10 | Deutsches Krebsforsch | Verfahren und Vorrichtung zur Messung von Fluoreszenz-Kreuzkorrelationen |
| US20020063863A1 (en) * | 2000-02-10 | 2002-05-30 | Peet Kask | Fluorescence intensity and lifetime distribution analysis |
Non-Patent Citations (2)
| Title |
|---|
| KELLER R A ET AL: "SINGLE-MOLECULE FLUORESCENCE ANALYSIS IN SOLUTION", APPLIED SPECTROSCOPY, THE SOCIETY FOR APPLIED SPECTROSCOPY. BALTIMORE, US, vol. 50, no. 7, 1 July 1996 (1996-07-01), pages 12A - 32A, XP000642337, ISSN: 0003-7028 * |
| MUSOLINO M ET AL: "AN INTEGRATED INSTRUMENTATION FOR LIGHT-SCATTERING AND TIME-RESOLVED FLUORESCENCE MEASUREMENTS", REVIEW OF SCIENTIFIC INSTRUMENTS, AMERICAN INSTITUTE OF PHYSICS. NEW YORK, US, vol. 66, no. 3, 1 March 1995 (1995-03-01), pages 2405 - 2410, XP000529679, ISSN: 0034-6748 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007101932A2 (fr) * | 2006-03-06 | 2007-09-13 | Horiba Abx Sas | Dispositif et procédé de mesure de photoluminescence, d'absorption et de diffraction d'objets microscopiques dans un fluide |
| WO2007101932A3 (fr) * | 2006-03-06 | 2007-11-01 | Horiba Abx Sas | Dispositif et procédé de mesure de photoluminescence, d'absorption et de diffraction d'objets microscopiques dans un fluide |
| WO2008091359A2 (fr) * | 2006-07-03 | 2008-07-31 | Ge Homeland Protection Inc. | Procédés et systèmes pour détecter des particules |
| WO2008091359A3 (fr) * | 2006-07-03 | 2008-10-02 | Ge Homeland Protection Inc | Procédés et systèmes pour détecter des particules |
| WO2010149391A1 (fr) * | 2009-06-26 | 2010-12-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Tête de mesure de particules, dispositif de mesure de particules et procédé de mesure de particules pour la mesure de la charge en particules de fluides |
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