US20050276812A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
DE10254601A1
(en)
|
2002-11-22 |
2004-06-03 |
Ganymed Pharmaceuticals Ag |
Gene products differentially expressed in tumors and their use
|
SG195524A1
(en)
|
2003-11-06 |
2013-12-30 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugation to ligands
|
US20060078558A1
(en)
*
|
2003-11-12 |
2006-04-13 |
Whitsett Jeffrey A |
Diagnosis, prognosis and treatment of pulmonary diseases
|
US20050186577A1
(en)
|
2004-02-20 |
2005-08-25 |
Yixin Wang |
Breast cancer prognostics
|
DE102004024617A1
(en)
|
2004-05-18 |
2005-12-29 |
Ganymed Pharmaceuticals Ag |
Differentially expressed in tumors gene products and their use
|
PL1791568T3
(en)
|
2004-08-16 |
2013-01-31 |
Quark Pharmaceuticals Inc |
Therapeutic uses of inhibitors of rtp801
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
AU2005286607B2
(en)
|
2004-09-23 |
2011-01-27 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
DK1802749T3
(en)
|
2004-10-21 |
2012-11-26 |
Mayo Foundation |
KASPP (LRRK2) gene, its preparation and use for the detection and treatment of neurodegenerative disorders
|
WO2006110748A2
(en)
*
|
2005-04-08 |
2006-10-19 |
The University Of Maryland, Baltimore |
Response gene to complement 32 (rgc-32) in disease
|
EP1790664A1
(en)
|
2005-11-24 |
2007-05-30 |
Ganymed Pharmaceuticals AG |
Monoclonal antibodies against claudin-18 for treatment of cancer
|
DOP2007000015A
(en)
|
2006-01-20 |
2007-08-31 |
Quark Biotech Inc |
THERAPEUTIC USES OF RTP801 INHIBITORS
|
WO2008054534A2
(en)
|
2006-05-11 |
2008-05-08 |
Quark Pharmaceuticals, Inc. |
Screening systems utilizing rtp801
|
EP2026843A4
(en)
|
2006-06-09 |
2011-06-22 |
Quark Pharmaceuticals Inc |
Therapeutic uses of inhibitors of rtp801l
|
EP2137205A2
(en)
|
2007-02-26 |
2009-12-30 |
Quark Pharmaceuticals, Inc. |
Inhibitors of rtp801 and their use in disease treatment
|
ES2490165T3
(en)
*
|
2007-09-11 |
2014-09-03 |
Cancer Prevention And Cure, Ltd. |
Method that facilitates the diagnosis and treatment of asthma and lung cancer
|
US8846036B2
(en)
|
2007-10-19 |
2014-09-30 |
Abbott Laboratories |
Antibodies that bind to mammalian NGAL and uses thereof
|
WO2009052392A1
(en)
*
|
2007-10-19 |
2009-04-23 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
EP2857522A3
(en)
|
2009-03-12 |
2015-10-14 |
Cancer Prevention And Cure, Ltd. |
Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy
|
KR101962476B1
(en)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
Immuno-conjugates and methods for producing them
|
EP2473529B1
(en)
*
|
2009-09-03 |
2016-02-10 |
Cancer Research Technology Limited |
Clec14a inhibitors
|
US8470980B2
(en)
|
2009-09-09 |
2013-06-25 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
EP2516462B1
(en)
|
2009-12-23 |
2015-05-06 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
DK2528625T3
(en)
|
2010-04-15 |
2013-10-14 |
Spirogen Sarl |
Pyrrolobenzodiazepines and their conjugates
|
CN114246952A
(en)
|
2010-06-08 |
2022-03-29 |
基因泰克公司 |
Cysteine engineered antibodies and conjugates
|
US20120121615A1
(en)
|
2010-11-17 |
2012-05-17 |
Flygare John A |
Alaninyl maytansinol antibody conjugates
|
UA113838C2
(en)
|
2010-12-20 |
2017-03-27 |
|
ANTIBODY Binding Mesothelin and Immunoconjugate
|
PT2665746T
(en)
|
2011-01-17 |
2021-02-03 |
Lykera Biomed S A |
Antibodies against the s100p protein for the treatment and diagnosis of cancer
|
ES2583688T3
(en)
*
|
2011-03-11 |
2016-09-21 |
F. Hoffmann-La Roche Ag |
FEN1 as a marker of chronic obstructive pulmonary disease (COPD)
|
EP3103810A3
(en)
|
2011-04-21 |
2017-03-08 |
Garvan Institute of Medical Research |
Modified variable domain molecules and methods for producing and using them
|
ES2567276T3
(en)
|
2011-05-12 |
2016-04-21 |
Genentech, Inc. |
LC-MS / MS method of monitoring multiple reactions to detect therapeutic antibodies in animal samples using frame-changing peptides
|
CN103987407B
(en)
|
2011-10-14 |
2016-08-24 |
麦迪穆有限责任公司 |
Pyrrolobenzodiazepines Zhuo and conjugate thereof
|
CA2848985A1
(en)
|
2012-02-01 |
2013-08-08 |
Compugen Ltd. |
C10rf32 antibodies, and uses thereof for treatment of cancer
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
WO2013167153A1
(en)
|
2012-05-09 |
2013-11-14 |
Ganymed Pharmaceuticals Ag |
Antibodies useful in cancer diagnosis
|
MX364327B
(en)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates.
|
JP6392763B2
(en)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugate
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
RS57694B1
(en)
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
ES2660029T3
(en)
|
2012-10-12 |
2018-03-20 |
Medimmune Limited |
Antibody-pyrrolobenzodiazepine conjugates
|
ES2680153T3
(en)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Anti-PSMA-pyrrolobenzodiazepine antibody conjugates
|
HUE039329T2
(en)
|
2012-10-12 |
2018-12-28 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
JP6340019B2
(en)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドMedImmune Limited |
Pyrrolobenzodiazepine and its conjugates
|
NZ710745A
(en)
|
2013-03-13 |
2019-03-29 |
Genentech Inc |
Pyrrolobenzodiazepines and conjugates thereof
|
AU2014230735B2
(en)
|
2013-03-13 |
2018-03-15 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EA201690195A1
(en)
|
2013-08-12 |
2016-05-31 |
Дженентек, Инк. |
ANTIBODY CONJUGATE CONNECTIONS ON THE BASIS OF DIMER 1- (HLORMETHYL) -2,3-DIGYDRO-1H-BENZO [E] INDOL AND METHODS OF APPLICATION AND TREATMENT
|
WO2015052532A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
US9950078B2
(en)
|
2013-10-11 |
2018-04-24 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
MX371092B
(en)
|
2013-12-16 |
2020-01-16 |
Genentech Inc |
Peptidomimetic compounds and antibody-drug conjugates thereof.
|
PE20161394A1
(en)
|
2013-12-16 |
2017-01-06 |
Genentech Inc |
PEPTIDOMIMETIC COMPOUNDS AND THEIR ANTIBODY-DRUG CONJUGATES
|
JP6980384B2
(en)
|
2013-12-16 |
2021-12-15 |
ジェネンテック, インコーポレイテッド |
1- (Chloromethyl) -2,3-dihydro-1H-benzo [E] indole dimer antibody-drug conjugate compound, and methods of use and treatment
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3191134B1
(en)
|
2014-09-12 |
2019-11-20 |
Genentech, Inc. |
Anthracycline disulfide intermediates, antibody-drug conjugates and methods
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
BR112017003236A2
(en)
|
2014-09-12 |
2017-11-28 |
Genentech Inc |
cysteine engineered antibodies, drug conjugates and antibodies, drug and antibody conjugate preparation method and pharmaceutical composition
|
CR20170099A
(en)
|
2014-09-17 |
2017-07-19 |
Genentech Inc |
PIRROLOBENZODIAZEPINAS AND CONJUGADOS DE ANTIBERPOS-DISULFURO DE LAS SISAS
|
MX2017006770A
(en)
|
2014-11-25 |
2018-02-09 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates.
|
EP3226909A1
(en)
|
2014-12-03 |
2017-10-11 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
MA43345A
(en)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
PYRROLOBENZODIAZEPINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
MA43354A
(en)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
CONJUGATE DRUG CONJUGATES WITH CLOUDY DISULPHIDE
|
MA45326A
(en)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
CALICHEAMICIN-ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
US20170315132A1
(en)
|
2016-03-25 |
2017-11-02 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
JP2019522633A
(en)
|
2016-05-20 |
2019-08-15 |
ジェネンテック, インコーポレイテッド |
PROTAC antibody conjugates and methods of use
|
CN109313200B
(en)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
Bioanalytical methods for characterizing site-specific antibody-drug conjugates
|
WO2017214024A1
(en)
|
2016-06-06 |
2017-12-14 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
WO2018065501A1
(en)
|
2016-10-05 |
2018-04-12 |
F. Hoffmann-La Roche Ag |
Methods for preparing antibody drug conjugates
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
PT3544636T
(en)
|
2017-02-08 |
2021-05-04 |
Medimmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
CN110709936A
(en)
|
2017-04-04 |
2020-01-17 |
肺癌蛋白质组学有限责任公司 |
Plasma-based protein profiling for early lung cancer prognosis
|
WO2018192944A1
(en)
|
2017-04-18 |
2018-10-25 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
KR20190141666A
(en)
|
2017-04-20 |
2019-12-24 |
에이디씨 테라퓨틱스 에스에이 |
Combination Therapy with Anti-AXL Antibody-Drug Conjugates
|
AU2018285562B2
(en)
|
2017-06-14 |
2024-01-18 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-CD19 ADC
|
ES2906965T3
(en)
|
2017-08-18 |
2022-04-21 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
WO2019060398A1
(en)
|
2017-09-20 |
2019-03-28 |
Ph Pharma Co., Ltd. |
Thailanstatin analogs
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
TW202037381A
(en)
|
2018-10-24 |
2020-10-16 |
瑞士商赫孚孟拉羅股份公司 |
Conjugated chemical inducers of degradation and methods of use
|
WO2020123275A1
(en)
|
2018-12-10 |
2020-06-18 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|