WO2003016882A1 - Measuring a substance in a biological sample - Google Patents
Measuring a substance in a biological sample Download PDFInfo
- Publication number
- WO2003016882A1 WO2003016882A1 PCT/US2002/022899 US0222899W WO03016882A1 WO 2003016882 A1 WO2003016882 A1 WO 2003016882A1 US 0222899 W US0222899 W US 0222899W WO 03016882 A1 WO03016882 A1 WO 03016882A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- electromagnetic radiation
- wavelength bands
- infrared
- organic substance
- wavelength
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract description 133
- 239000012472 biological sample Substances 0.000 title claims abstract description 66
- 238000000034 method Methods 0.000 claims abstract description 136
- 230000005670 electromagnetic radiation Effects 0.000 claims abstract description 108
- 239000008103 glucose Substances 0.000 claims description 145
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 143
- 238000002835 absorbance Methods 0.000 claims description 62
- 238000001228 spectrum Methods 0.000 claims description 52
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- 238000001514 detection method Methods 0.000 claims description 45
- 239000013060 biological fluid Substances 0.000 claims description 43
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
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- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 239000012042 active reagent Substances 0.000 description 1
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
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- 239000012503 blood component Substances 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
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- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Optics & Photonics (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002457753A CA2457753A1 (en) | 2001-08-14 | 2002-07-18 | Measuring a substance in a biological sample |
EP02756523A EP1428013A4 (en) | 2001-08-14 | 2002-07-18 | Measuring a substance in a biological sample |
US10/692,996 US20040147034A1 (en) | 2001-08-14 | 2003-10-24 | Method and apparatus for measuring a substance in a biological sample |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31216501P | 2001-08-14 | 2001-08-14 | |
US60/312,165 | 2001-08-14 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/692,996 Continuation-In-Part US20040147034A1 (en) | 2001-08-14 | 2003-10-24 | Method and apparatus for measuring a substance in a biological sample |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003016882A1 true WO2003016882A1 (en) | 2003-02-27 |
Family
ID=23210165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/022899 WO2003016882A1 (en) | 2001-08-14 | 2002-07-18 | Measuring a substance in a biological sample |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1428013A4 (en) |
CA (1) | CA2457753A1 (en) |
WO (1) | WO2003016882A1 (en) |
Cited By (59)
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EP1464273A1 (en) * | 2003-04-03 | 2004-10-06 | Matsushita Electric Industrial Co., Ltd. | Method and device for measuring concentration of specific component |
WO2005047869A1 (en) * | 2003-11-03 | 2005-05-26 | Roche Diagnostics Gmbh | Flow-through measuring cell, spectrometer and method for analysing biological fluids |
US6958809B2 (en) | 2001-11-08 | 2005-10-25 | Optiscan Biomedical Corporation | Reagent-less whole-blood glucose meter |
US7050157B2 (en) | 2001-11-08 | 2006-05-23 | Optiscan Biomedical Corp. | Reagent-less whole-blood glucose meter |
US7061593B2 (en) | 2001-11-08 | 2006-06-13 | Optiscan Biomedical Corp. | Device and method for in vitro determination of analyte concentrations within body fluids |
EP1685377A2 (en) * | 2003-10-24 | 2006-08-02 | Jayavant P. Gore | Measuring a substance in a biological sample |
US7288768B2 (en) | 2002-07-18 | 2007-10-30 | Purdue Research Foundation | Method for measuring the amount of an organic substance in a food product with infrared electromagnetic radiation |
US7722537B2 (en) | 2005-02-14 | 2010-05-25 | Optiscan Biomedical Corp. | Method and apparatus for detection of multiple analytes |
US7738085B2 (en) | 2001-11-08 | 2010-06-15 | Optiscan Biomedical Corporation | Device and method for in vitro determination of analyte concentration within body fluids |
US7785258B2 (en) | 2005-10-06 | 2010-08-31 | Optiscan Biomedical Corporation | System and method for determining a treatment dose for a patient |
US7860543B2 (en) | 2005-02-14 | 2010-12-28 | Optiscan Biomedical Corporation | Analyte detection system with reduced sample volume |
US8251907B2 (en) | 2005-02-14 | 2012-08-28 | Optiscan Biomedical Corporation | System and method for determining a treatment dose for a patient |
US8412293B2 (en) | 2007-07-16 | 2013-04-02 | Optiscan Biomedical Corporation | Systems and methods for determining physiological parameters using measured analyte values |
US8620397B2 (en) | 2004-10-21 | 2013-12-31 | Optiscan Biomedical Corporation | Method and apparatus for determining an analyte concentration in a sample having interferents |
US8928877B2 (en) | 2011-07-06 | 2015-01-06 | Optiscan Biomedical Corporation | Sample cell for fluid analysis system |
US8936755B2 (en) | 2005-03-02 | 2015-01-20 | Optiscan Biomedical Corporation | Bodily fluid composition analyzer with disposable cassette |
US8992443B2 (en) | 2005-02-14 | 2015-03-31 | Optiscan Biomedical Corporation | Fluid handling cassette |
US9091676B2 (en) | 2010-06-09 | 2015-07-28 | Optiscan Biomedical Corp. | Systems and methods for measuring multiple analytes in a sample |
US9289169B2 (en) | 2007-05-18 | 2016-03-22 | Optiscan Biomedical Corp. | Analyte monitoring systems and methods |
US9302045B2 (en) | 2008-09-12 | 2016-04-05 | Optiscan Biomedical Corporation | Fluid component analysis system and method for glucose monitoring and control |
US9326717B2 (en) | 2009-07-20 | 2016-05-03 | Optiscan Biomedical Corporation | Adjustable connector and dead space reduction |
US9414782B2 (en) | 2007-10-10 | 2016-08-16 | Optiscan Biomedical Corporation | Fluid component analysis systems and methods for glucose monitoring and control |
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US9554742B2 (en) | 2009-07-20 | 2017-01-31 | Optiscan Biomedical Corporation | Fluid analysis system |
US9561001B2 (en) | 2005-10-06 | 2017-02-07 | Optiscan Biomedical Corporation | Fluid handling cassette system for body fluid analyzer |
US9632013B2 (en) | 2007-05-18 | 2017-04-25 | Optiscan Biomedical Corporation | Fluid injection and safety system |
US9717449B2 (en) | 2007-10-25 | 2017-08-01 | Dexcom, Inc. | Systems and methods for processing sensor data |
US9863837B2 (en) | 2013-12-18 | 2018-01-09 | OptiScan Biomedical Coporation | Systems and methods for detecting leaks |
US9895089B2 (en) | 2003-08-01 | 2018-02-20 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US10028692B2 (en) | 2009-07-20 | 2018-07-24 | Optiscan Biomedical Corporation | Adjustable connector, improved fluid flow and reduced clotting risk |
US10052055B2 (en) | 2003-08-01 | 2018-08-21 | Dexcom, Inc. | Analyte sensor |
US10475529B2 (en) | 2011-07-19 | 2019-11-12 | Optiscan Biomedical Corporation | Method and apparatus for analyte measurements using calibration sets |
US10980461B2 (en) | 2008-11-07 | 2021-04-20 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
US11000215B1 (en) | 2003-12-05 | 2021-05-11 | Dexcom, Inc. | Analyte sensor |
US11324889B2 (en) | 2020-02-14 | 2022-05-10 | Insulet Corporation | Compensation for missing readings from a glucose monitor in an automated insulin delivery system |
US11386996B2 (en) | 2014-01-30 | 2022-07-12 | Insulet Netherlands B.V. | Therapeutic product delivery system and method of pairing |
US11382539B2 (en) | 2006-10-04 | 2022-07-12 | Dexcom, Inc. | Analyte sensor |
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EP1428013A4 (en) | 2007-10-31 |
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