WO2002076377A1 - Mononucleosome and process for producing the same, method of assaying antibody specific to nucleosome, method of diagnosing autoimmune disease, process for producing nucleosome dna, dna plate, process for producing dna plate and method of assaying anti-dna antibody - Google Patents
Mononucleosome and process for producing the same, method of assaying antibody specific to nucleosome, method of diagnosing autoimmune disease, process for producing nucleosome dna, dna plate, process for producing dna plate and method of assaying anti-dna antibodyInfo
- Publication number
- WO2002076377A1 WO2002076377A1 PCT/JP2002/002664 JP0202664W WO02076377A1 WO 2002076377 A1 WO2002076377 A1 WO 2002076377A1 JP 0202664 W JP0202664 W JP 0202664W WO 02076377 A1 WO02076377 A1 WO 02076377A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dna
- producing
- nucleosome
- assaying
- plate
- Prior art date
Links
- 108010047956 Nucleosomes Proteins 0.000 title abstract 6
- 210000001623 Nucleosomes Anatomy 0.000 title abstract 6
- 102000004965 antibodies Human genes 0.000 title abstract 4
- 108090001123 antibodies Proteins 0.000 title abstract 4
- 229920003013 deoxyribonucleic acid Polymers 0.000 title 3
- 206010003816 Autoimmune disease Diseases 0.000 title 1
- 230000003172 anti-dna Effects 0.000 title 1
- 201000009596 autoimmune hypersensitivity disease Diseases 0.000 title 1
Abstract
It is intended to provide a process whereby a highly pure mononucleosome can be conveniently and efficiently produced. Namely, a process for producing a mononucleosome involving: the step of capturing and collecting a nucleosome contained in a sample by using an antibody specific to the nucleosome; the step of dissociating and collecting the thus captured nucleosome from the antibody; and the step of isolating and purifying a mononucleosome from the collected nucleosome depending on molecular weight.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002574893A JP4276843B2 (en) | 2001-03-23 | 2002-03-20 | Mononucleosome and method for producing the same, method for measuring antibody specific to nucleosome, method for diagnosing autoimmune disease, method for producing nucleosome DNA, DNA plate, method for producing DNA plate, and method for measuring anti-DNA antibody |
| AU2002238994A AU2002238994A1 (en) | 2001-03-23 | 2002-03-20 | Mononucleosome and process for producing the same, method of assaying antibody specific to nucleosome, method of diagnosing autoimmune disease, process for producing nucleosome dna, dna plate, process for producing dna plate and method of assaying anti-dna antibody |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001084480 | 2001-03-23 | ||
| JP2001-84480 | 2001-03-23 | ||
| JP2001-291182 | 2001-09-25 | ||
| JP2001291182 | 2001-09-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2002076377A2 WO2002076377A2 (en) | 2002-10-03 |
| WO2002076377A1 true WO2002076377A1 (en) | 2002-10-03 |
| WO2002076377A3 WO2002076377A3 (en) | 2002-11-21 |
Family
ID=
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US9430611B2 (en) | 2005-11-26 | 2016-08-30 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
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