WO2002062976A3 - Serine proteases - Google Patents

Serine proteases Download PDF

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Publication number
WO2002062976A3
WO2002062976A3 PCT/GB2002/000505 GB0200505W WO02062976A3 WO 2002062976 A3 WO2002062976 A3 WO 2002062976A3 GB 0200505 W GB0200505 W GB 0200505W WO 02062976 A3 WO02062976 A3 WO 02062976A3
Authority
WO
WIPO (PCT)
Prior art keywords
serine proteases
proteins
termed
diagnosis
disease
Prior art date
Application number
PCT/GB2002/000505
Other languages
French (fr)
Other versions
WO2002062976A2 (en
Inventor
Richard Joseph Fagan
Christopher Benjamin Phelps
Tania Maria Rodrigues
Original Assignee
Inpharmatica Ltd
Richard Joseph Fagan
Christopher Benjamin Phelps
Tania Maria Rodrigues
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharmatica Ltd, Richard Joseph Fagan, Christopher Benjamin Phelps, Tania Maria Rodrigues filed Critical Inpharmatica Ltd
Priority to AU2002229906A priority Critical patent/AU2002229906A1/en
Publication of WO2002062976A2 publication Critical patent/WO2002062976A2/en
Publication of WO2002062976A3 publication Critical patent/WO2002062976A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to novel proteins, termed AAF384335.1, CAB00991.1, CAB73737.1 and AAC67798.1, herein identified as serine proteases and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
PCT/GB2002/000505 2001-02-06 2002-02-06 Serine proteases WO2002062976A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002229906A AU2002229906A1 (en) 2001-02-06 2002-02-06 Serine proteases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0102929.7A GB0102929D0 (en) 2001-02-06 2001-02-06 Novel proteins
GB0102929.7 2001-02-06

Publications (2)

Publication Number Publication Date
WO2002062976A2 WO2002062976A2 (en) 2002-08-15
WO2002062976A3 true WO2002062976A3 (en) 2003-02-20

Family

ID=9908209

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/000505 WO2002062976A2 (en) 2001-02-06 2002-02-06 Serine proteases

Country Status (3)

Country Link
AU (1) AU2002229906A1 (en)
GB (1) GB0102929D0 (en)
WO (1) WO2002062976A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000345A1 (en) * 1989-06-26 1991-01-10 Novo Nordisk A/S A mutated subtilisin protease
WO1999027105A2 (en) * 1997-11-21 1999-06-03 Genset Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000345A1 (en) * 1989-06-26 1991-01-10 Novo Nordisk A/S A mutated subtilisin protease
WO1999027105A2 (en) * 1997-11-21 1999-06-03 Genset Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 October 2000 (2000-10-01), "CT149 hypothetical protein", XP002212751, retrieved from EMBL Database accession no. Q9JS65 *
DATABASE EMBL [online] 13 September 1999 (1999-09-13), "Chlamydia pneumonia transmembrane protein sequence", XP002212752, retrieved from EMBL Database accession no. AAY34755 *
DATABASE EMBL [online] 13 September 1999 (1999-09-13), "Genome sequence of Chlamydia pneumoniae", XP002212754, retrieved from EMBL Database accession no. AAX91990 *
DATABASE EMBL [online] 14 March 2000 (2000-03-14), READ, T.D. ET AL.: "Chlamydophila pneumoniae AR39", XP002212753, retrieved from EMBL Database accession no. AE002219 *

Also Published As

Publication number Publication date
GB0102929D0 (en) 2001-03-21
AU2002229906A1 (en) 2002-08-19
WO2002062976A2 (en) 2002-08-15

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