WO2000036102A3 - Secreted and transmembrane polypeptides and nucleic acids encoding the same - Google Patents

Secreted and transmembrane polypeptides and nucleic acids encoding the same Download PDF

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Publication number
WO2000036102A3
WO2000036102A3 PCT/US1999/028634 US9928634W WO0036102A3 WO 2000036102 A3 WO2000036102 A3 WO 2000036102A3 US 9928634 W US9928634 W US 9928634W WO 0036102 A3 WO0036102 A3 WO 0036102A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
present
secreted
same
nucleic acids
Prior art date
Application number
PCT/US1999/028634
Other languages
French (fr)
Other versions
WO2000036102A2 (en
Inventor
David Botstein
Luc Desnoyers
Napoleone Ferrara
Sherman Fong
Wei-Qiang Gao
Audrey Goddard
Austin L Gurney
James Pan
Margaret Ann Roy
Timothy A Stewart
Daniel Tumas
Colin K Watanabe
William I Wood
Original Assignee
Genentech Inc
David Botstein
Luc Desnoyers
Napoleone Ferrara
Sherman Fong
Gao Wei Qiang
Audrey Goddard
Austin L Gurney
James Pan
Margaret Ann Roy
Timothy A Stewart
Daniel Tumas
Colin K Watanabe
William I Wood
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Application filed by Genentech Inc, David Botstein, Luc Desnoyers, Napoleone Ferrara, Sherman Fong, Gao Wei Qiang, Audrey Goddard, Austin L Gurney, James Pan, Margaret Ann Roy, Timothy A Stewart, Daniel Tumas, Colin K Watanabe, William I Wood filed Critical Genentech Inc
Priority to KR10-2004-7006172A priority Critical patent/KR100468975B1/en
Priority to AU19320/00A priority patent/AU777006B2/en
Priority to CA002348757A priority patent/CA2348757A1/en
Priority to KR10-2001-7007461A priority patent/KR100468978B1/en
Priority to KR10-2004-7006173A priority patent/KR100459831B1/en
Priority to KR10-2004-7006174A priority patent/KR100468976B1/en
Priority to NZ511303A priority patent/NZ511303A/en
Priority to JP2000588351A priority patent/JP2003521229A/en
Priority to IL14279499A priority patent/IL142794A0/en
Priority to EP99962992A priority patent/EP1141285A2/en
Priority to MXPA01006057A priority patent/MXPA01006057A/en
Priority to KR10-2004-7013508A priority patent/KR100468977B1/en
Priority to DE69940681T priority patent/DE69940681D1/en
Priority to AU31077/00A priority patent/AU773055C/en
Priority to EP05019847A priority patent/EP1642968B1/en
Priority to CA002367334A priority patent/CA2367334A1/en
Priority to JP2000603371A priority patent/JP2003525585A/en
Priority to AT05019847T priority patent/ATE439431T1/en
Priority to EP05019850A priority patent/EP1634892A3/en
Priority to AT05019849T priority patent/ATE427319T1/en
Priority to EP99965090A priority patent/EP1159422A1/en
Priority to DE69941273T priority patent/DE69941273D1/en
Priority to EP05019848A priority patent/EP1642906A3/en
Priority to PCT/US1999/028551 priority patent/WO2000053750A1/en
Priority to EP05019846A priority patent/EP1642967A3/en
Priority to EP05019849A priority patent/EP1642907B1/en
Priority to KR1020017011361A priority patent/KR100566839B1/en
Priority to PT05018356T priority patent/PT1607402E/en
Priority to DK05018357T priority patent/DK1626058T3/en
Priority to PT05018355T priority patent/PT1623989E/en
Priority to EP05018357A priority patent/EP1626058B1/en
Priority to KR10-2001-7011391A priority patent/KR100512819B1/en
Priority to CA002479511A priority patent/CA2479511A1/en
Priority to PT05018358T priority patent/PT1623990E/en
Priority to PT05018354T priority patent/PT1632499E/en
Priority to PCT/US2000/003565 priority patent/WO2001053486A1/en
Priority to ES05018354T priority patent/ES2290834T3/en
Priority to PT05018357T priority patent/PT1626058E/en
Priority to AT05018357T priority patent/ATE377025T1/en
Priority to AU28794/00A priority patent/AU756400B2/en
Priority to CA002365610A priority patent/CA2365610A1/en
Priority to EP05018354A priority patent/EP1632499B9/en
Priority to AT05018356T priority patent/ATE348108T1/en
Priority to EP05018356A priority patent/EP1607402B1/en
Priority to DK05018355T priority patent/DK1623989T3/en
Priority to EP05018353A priority patent/EP1626084B1/en
Priority to ES05018353T priority patent/ES2321954T3/en
Priority to AT05018358T priority patent/ATE380195T1/en
Priority to ES05018356T priority patent/ES2279473T3/en
Priority to EP00907270A priority patent/EP1173563A1/en
Priority to ES05018357T priority patent/ES2296029T3/en
Priority to EP05018355A priority patent/EP1623989B1/en
Priority to CA002479498A priority patent/CA2479498A1/en
Priority to DK05018358T priority patent/DK1623990T3/en
Priority to ES05018355T priority patent/ES2289630T3/en
Priority to CA002479494A priority patent/CA2479494C/en
Priority to ES05018358T priority patent/ES2298896T3/en
Priority to JP2001553947A priority patent/JP2004520003A/en
Priority to DK05018356T priority patent/DK1607402T3/en
Priority to AT05018355T priority patent/ATE364628T1/en
Priority to DK05018354T priority patent/DK1632499T3/en
Priority to AT05018354T priority patent/ATE363489T1/en
Priority to AT05018353T priority patent/ATE422536T1/en
Priority to CA002479476A priority patent/CA2479476C/en
Priority to EP05018358A priority patent/EP1623990B1/en
Priority to AU35144/00A priority patent/AU3514400A/en
Priority to CA002362427A priority patent/CA2362427A1/en
Priority to EP00913764A priority patent/EP1220905A2/en
Priority to KR1020017011406A priority patent/KR20010103046A/en
Priority to JP2000603379A priority patent/JP2004516227A/en
Priority to PCT/US2000/005841 priority patent/WO2000053758A2/en
Priority to ES00941164T priority patent/ES2287020T3/en
Priority to EP07005022A priority patent/EP1870464A3/en
Priority to PCT/US2000/014941 priority patent/WO2000073348A2/en
Priority to EP07005023A priority patent/EP1867719A3/en
Priority to AT00941164T priority patent/ATE357518T1/en
Priority to EP07004855A priority patent/EP1820860A3/en
Priority to DE60034036T priority patent/DE60034036T2/en
Priority to AU55911/00A priority patent/AU5591100A/en
Priority to CA002373915A priority patent/CA2373915A1/en
Priority to DK00941164T priority patent/DK1185648T3/en
Priority to EP07005021A priority patent/EP1873244A3/en
Priority to JP2001500672A priority patent/JP2003524406A/en
Priority to EP00941164A priority patent/EP1185648B1/en
Priority to AU54601/00A priority patent/AU5460100A/en
Priority to PCT/US2000/015264 priority patent/WO2000073452A2/en
Publication of WO2000036102A2 publication Critical patent/WO2000036102A2/en
Publication of WO2000036102A3 publication Critical patent/WO2000036102A3/en
Priority to CA002490853A priority patent/CA2490853A1/en
Priority to CA002491258A priority patent/CA2491258A1/en
Priority to EP06000586A priority patent/EP1688497A1/en
Priority to EP06000582A priority patent/EP1666495A1/en
Priority to CA002492070A priority patent/CA2492070A1/en
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Priority to EP06000584A priority patent/EP1669371A3/en
Priority to CA002496312A priority patent/CA2496312A1/en
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Priority to CA002391455A priority patent/CA2391455A1/en
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Priority to IL142794A priority patent/IL142794A/en
Priority to US09/929,769 priority patent/US6914130B2/en
Priority to US09/941,992 priority patent/US20030082546A1/en
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Priority to AU2003200731A priority patent/AU2003200731C1/en
Priority to AU2003200740A priority patent/AU2003200740C1/en
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Priority to JP2007326613A priority patent/JP2008161190A/en
Priority to JP2007326609A priority patent/JP2008148701A/en
Priority to JP2007325484A priority patent/JP2008148699A/en
Priority to IL188580A priority patent/IL188580A0/en
Priority to IL188581A priority patent/IL188581A0/en
Priority to IL188577A priority patent/IL188577A0/en
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Priority to JP2008163394A priority patent/JP2009039097A/en
Priority to JP2008166460A priority patent/JP2009000114A/en
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

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Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
PCT/US1999/028634 1996-11-06 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same WO2000036102A2 (en)

Priority Applications (386)

Application Number Priority Date Filing Date Title
KR10-2004-7006172A KR100468975B1 (en) 1999-02-12 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
AU19320/00A AU777006B2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002348757A CA2348757A1 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
KR10-2001-7007461A KR100468978B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
KR10-2004-7006173A KR100459831B1 (en) 1999-01-12 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
KR10-2004-7006174A KR100468976B1 (en) 1999-02-10 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
NZ511303A NZ511303A (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same with homology to Hep27 protein
JP2000588351A JP2003521229A (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding them
IL14279499A IL142794A0 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP99962992A EP1141285A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
MXPA01006057A MXPA01006057A (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same.
KR10-2004-7013508A KR100468977B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
DE69940681T DE69940681D1 (en) 1999-03-08 1999-12-02 Composition and method for the diagnosis of tumors
AU31077/00A AU773055C (en) 1999-03-08 1999-12-02 Compositions and methods for the treatment of tumors
EP05019847A EP1642968B1 (en) 1999-03-08 1999-12-02 Composition and methods for the diagnosis of tumours
CA002367334A CA2367334A1 (en) 1999-03-08 1999-12-02 Compositions and methods for the treatment of tumors
JP2000603371A JP2003525585A (en) 1999-03-08 1999-12-02 Compositions and methods for treating tumors
AT05019847T ATE439431T1 (en) 1999-03-08 1999-12-02 COMPOSITION AND METHOD FOR DIAGNOSIS OF TUMORS
EP05019850A EP1634892A3 (en) 1999-03-08 1999-12-02 Composition and methods for the diagnosis of tumours
AT05019849T ATE427319T1 (en) 1999-03-08 1999-12-02 COMPOSITION AND METHOD FOR DIAGNOSIS OF TUMORS
EP99965090A EP1159422A1 (en) 1999-03-08 1999-12-02 Compositions and methods for the treatment of tumors
DE69941273T DE69941273D1 (en) 1999-03-08 1999-12-02 Compilation and method for the diagnosis of tumors
EP05019848A EP1642906A3 (en) 1999-03-08 1999-12-02 Composition and methods for the diagnosis of tumours
PCT/US1999/028551 WO2000053750A1 (en) 1999-03-08 1999-12-02 Compositions and methods for the treatment of tumors
EP05019846A EP1642967A3 (en) 1999-03-08 1999-12-02 Composition and methods for the diagnosis of tumours
EP05019849A EP1642907B1 (en) 1999-03-08 1999-12-02 Composition and methods for the diagnosis of tumours
KR1020017011361A KR100566839B1 (en) 1999-03-08 1999-12-02 Compositions and Methods for The Treatment of Tumor
PT05018356T PT1607402E (en) 1999-03-08 2000-02-11 Method for the diagnosis of tumour
DK05018357T DK1626058T3 (en) 1999-03-08 2000-02-11 Tumor diagnostic compositions and methods
PT05018355T PT1623989E (en) 1999-03-08 2000-02-11 Compositions and methods for the diagnosis of tumours
EP05018357A EP1626058B1 (en) 1999-03-08 2000-02-11 Compositions and methods for the diagnosis of tumour
KR10-2001-7011391A KR100512819B1 (en) 1999-03-08 2000-02-11 Compositions and Methods for the Treatment of Tumor
CA002479511A CA2479511A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
PT05018358T PT1623990E (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumours
PT05018354T PT1632499E (en) 1999-03-08 2000-02-11 Gene sequences amplified in tumours and their diagnostic uses
PCT/US2000/003565 WO2001053486A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
ES05018354T ES2290834T3 (en) 1999-03-08 2000-02-11 SEQUENCES OF AMPLIFIED GENES IN TUMORS AND THEIR DIAGNOSTIC USES.
PT05018357T PT1626058E (en) 1999-03-08 2000-02-11 Compositions and methods for the diagnosis of tumour
AT05018357T ATE377025T1 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND METHODS FOR DIAGNOSING TUMORS
AU28794/00A AU756400B2 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
CA002365610A CA2365610A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
EP05018354A EP1632499B9 (en) 1999-03-08 2000-02-11 Gene sequences amplified in tumours and their diagnostic uses
AT05018356T ATE348108T1 (en) 1999-03-08 2000-02-11 METHOD FOR DETECTING TUMORS
EP05018356A EP1607402B1 (en) 1999-03-08 2000-02-11 Method for the diagnosis of tumour
DK05018355T DK1623989T3 (en) 1999-03-08 2000-02-11 Compositions and Methods for Diagnosing Tumors
EP05018353A EP1626084B1 (en) 1999-03-08 2000-02-11 Compositions and methods for the diagnosis of tumours
ES05018353T ES2321954T3 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND PROCEDURES FOR TUMORS DIAGNOSIS.
AT05018358T ATE380195T1 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND METHODS FOR TREATING TUMORS
ES05018356T ES2279473T3 (en) 1999-03-08 2000-02-11 TUMOR DIAGNOSIS PROCEDURE.
EP00907270A EP1173563A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumour
ES05018357T ES2296029T3 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND PROCEDURES FOR TUMORS DIAGNOSIS.
EP05018355A EP1623989B1 (en) 1999-03-08 2000-02-11 Compositions and methods for the diagnosis of tumours
CA002479498A CA2479498A1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
DK05018358T DK1623990T3 (en) 1999-03-08 2000-02-11 Tumor Treatment Compositions and Methods
ES05018355T ES2289630T3 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND PROCEDURES FOR TUMORS DIAGNOSIS.
CA002479494A CA2479494C (en) 1999-03-08 2000-02-11 Compositions and methods associated with pro5725 and its use for the diagnosis of lung and colon tumor
ES05018358T ES2298896T3 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND PROCEDURES FOR TUMOR TREATMENT.
JP2001553947A JP2004520003A (en) 1999-03-08 2000-02-11 Compositions and methods for treating tumors
DK05018356T DK1607402T3 (en) 1999-03-08 2000-02-11 Tumor Treatment Compositions and Methods
AT05018355T ATE364628T1 (en) 1999-03-08 2000-02-11 METHODS AND COMPOSITIONS FOR DIAGNOSING TUMORS
DK05018354T DK1632499T3 (en) 1999-03-08 2000-02-11 Gene sequences amplified in tumors and diagnostic applications thereof
AT05018354T ATE363489T1 (en) 1999-03-08 2000-02-11 GENE SEQUENCES REPLICATED IN TUMORS AND THEIR DIAGNOSTIC USES
AT05018353T ATE422536T1 (en) 1999-03-08 2000-02-11 COMPOSITIONS AND METHODS FOR DIAGNOSIS OF TUMORS
CA002479476A CA2479476C (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumor
EP05018358A EP1623990B1 (en) 1999-03-08 2000-02-11 Compositions and methods for the treatment of tumours
AU35144/00A AU3514400A (en) 1999-03-08 2000-03-02 Compositions and methods for the treatment of immune related diseases
CA002362427A CA2362427A1 (en) 1999-03-08 2000-03-02 Compositions and methods for the treatment of immune related diseases
EP00913764A EP1220905A2 (en) 1999-03-08 2000-03-02 Composition and methods for the treatment of immune related diseases
KR1020017011406A KR20010103046A (en) 1999-03-08 2000-03-02 Compositions and Methods for the Treatment of Immune Related Diseases
JP2000603379A JP2004516227A (en) 1999-03-08 2000-03-02 Compositions and methods for treating immune-related diseases
PCT/US2000/005841 WO2000053758A2 (en) 1999-03-08 2000-03-02 Compositions and methods for the treatment of immune related diseases
ES00941164T ES2287020T3 (en) 1999-06-02 2000-05-30 PROCEDURE AND COMPOSITIONS TO INHIBIT THE GROWTH OF NEOPLASSIC CELLS.
EP07005022A EP1870464A3 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
PCT/US2000/014941 WO2000073348A2 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
EP07005023A EP1867719A3 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
AT00941164T ATE357518T1 (en) 1999-06-02 2000-05-30 METHODS AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH
EP07004855A EP1820860A3 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
DE60034036T DE60034036T2 (en) 1999-06-02 2000-05-30 METHOD AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH
AU55911/00A AU5591100A (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
CA002373915A CA2373915A1 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
DK00941164T DK1185648T3 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
EP07005021A EP1873244A3 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
JP2001500672A JP2003524406A (en) 1999-06-02 2000-05-30 Compositions and methods for inhibiting tumor cell growth
EP00941164A EP1185648B1 (en) 1999-06-02 2000-05-30 Methods and compositions for inhibiting neoplastic cell growth
AU54601/00A AU5460100A (en) 1999-06-02 2000-06-02 Compositions and methods for the treatment of immune related diseases
PCT/US2000/015264 WO2000073452A2 (en) 1999-06-02 2000-06-02 Compositions and methods for the treatment of immune related diseases
CA002490853A CA2490853A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002491258A CA2491258A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000586A EP1688497A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000582A EP1666495A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002492070A CA2492070A1 (en) 1999-12-01 2000-12-01 Lung tumor marker pro4329 polypeptides and nucleic acids encoding the same
EP06000581A EP1666494A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000584A EP1669371A3 (en) 1999-12-01 2000-12-01 Composition and methods for the diagnosis of tumours
CA002496312A CA2496312A1 (en) 1999-12-01 2000-12-01 Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same
EP06000585A EP1661996A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002492049A CA2492049A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2001542531A JP2004522404A (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding them
CA002391455A CA2391455A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2709291A CA2709291A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000583A EP1686134A3 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002490909A CA2490909A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP10005292A EP2228446A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptieds and nucleic acids encoding the same
CA002491433A CA2491433A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU20554/01A AU2055401A (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002494705A CA2494705A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000589A EP1661997A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000588A EP1690873A3 (en) 1999-12-01 2000-12-01 Composition and methods for the diagnosis of tumours
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA002491610A CA2491610A1 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP05025102A EP1672070A3 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP06000587A EP1690872A3 (en) 1999-12-01 2000-12-01 Composition and methods for the diagnosis of tumours
EP00983846A EP1250426A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding same
IL142794A IL142794A (en) 1998-12-16 2001-04-25 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/929,769 US6914130B2 (en) 1998-06-17 2001-08-14 Compositions and methods for the diagnosis and treatment of tumor
US09/941,992 US20030082546A1 (en) 1996-11-06 2001-08-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/993,667 US20030022187A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,726 US20030054359A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,443 US20030054987A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/993,583 US7074897B2 (en) 1997-06-16 2001-11-14 Pro943 polypeptides
US09/991,163 US20020132253A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,711 US20030032023A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,562 US20030027985A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,427 US20030073809A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/991,073 US20020127576A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,436 US20020198148A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,444 US6930170B2 (en) 1997-06-16 2001-11-14 PRO1184 polypeptides
US09/990,456 US20020137890A1 (en) 1997-03-31 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/993,469 US20030068623A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,442 US20020132252A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/992,521 US20030083461A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,438 US20030027754A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/991,854 US20030059780A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,440 US20030060407A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/993,748 US20030069403A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/992,598 US6956108B2 (en) 1997-06-16 2001-11-14 PRO1184 antibodies
US09/993,687 US20020198149A1 (en) 1997-06-16 2001-11-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,349 US7034106B2 (en) 1997-06-16 2001-11-15 Pro1159 polypeptides
US09/998,041 US7309775B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,585 US7166282B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,573 US20030049682A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,614 US20030124531A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,601 US20030054404A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/998,156 US20030044806A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/998,041 US20030119001A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,440 US20030059833A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,542 US20030068647A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,384 US7119177B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,559 US20030054403A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,653 US7034122B2 (en) 1997-06-16 2001-11-15 Antibodies to PRO1159 polypeptides
US09/997,857 US20030064375A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,529 US7309761B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,601 US7189814B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,641 US7112656B2 (en) 1997-06-16 2001-11-15 PRO1312 polypeptides
US09/997,585 US20030119055A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,428 US20030027162A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,333 US6953836B2 (en) 1997-06-16 2001-11-15 PRO844 polypeptides
US09/997,384 US20030087305A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,641 US20030224358A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,666 US7244816B2 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,628 US20030059782A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,666 US20030027163A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,514 US7019116B2 (en) 1997-06-16 2001-11-15 PRO 1387 polypeptides
US09/997,683 US20030059783A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/997,529 US20030134284A1 (en) 1997-06-16 2001-11-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/991,172 US20030050457A1 (en) 1997-06-16 2001-11-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/991,150 US20030194760A1 (en) 1997-06-16 2001-11-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/991,157 US7101687B2 (en) 1997-06-16 2001-11-16 Nucleic acids encoding PRO943
US09/991,181 US6913919B2 (en) 1997-06-16 2001-11-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,437 US20030045463A1 (en) 1997-06-16 2001-11-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/990,441 US7041804B2 (en) 1997-06-16 2001-11-16 Antibodies to PRO1387 polypeptides
US09/989,721 US20020142961A1 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,279 US7083978B2 (en) 1997-06-16 2001-11-19 Nucleic acid encoding PRO1111 polypeptides
US09/989,726 US7018811B2 (en) 1997-06-16 2001-11-19 Nucleic acids encoding PRO189 polypeptides
US09/989,727 US20020072497A1 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,732 US7037679B2 (en) 1997-06-16 2001-11-19 Nucleic acids encoding PRO1184 polypeptides
US09/989,735 US6972185B2 (en) 1997-06-16 2001-11-19 Nucleic acids encoding PRO844 polypeptides
US09/989,723 US20020072092A1 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,734 US7491529B2 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,729 US20030059831A1 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,328 US7056736B2 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,862 US20030130182A1 (en) 1997-11-05 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,722 US20020072067A1 (en) 1997-06-16 2001-11-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,724 US7060812B2 (en) 1997-06-16 2001-11-20 PRO1312 nucleic acids
US09/989,725 US20030139329A1 (en) 1997-06-16 2001-11-20 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,730 US7157247B2 (en) 1997-06-16 2001-11-20 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,728 US7029873B2 (en) 1997-06-16 2001-11-20 Nucleic acids to PRO1387 polypeptides
US09/989,731 US20020103125A1 (en) 1997-06-16 2001-11-20 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/989,293 US7034136B2 (en) 1997-06-16 2001-11-20 Nucleic acids encoding PRO1159 polypeptides
US10/001,054 US20020192209A1 (en) 1997-09-17 2001-11-30 Methods and compositions for inhibiting neoplastic cell growth
US10/028,072 US20030004311A1 (en) 1997-06-18 2001-12-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,396 US20030077657A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,223 US20020164646A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,167 US20020182618A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,167 US7101984B2 (en) 1999-02-12 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,326 US20020098507A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,245 US20020160392A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,244 US20020192668A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/032,996 US20030054447A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,301 US6930172B2 (en) 1999-01-12 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,435 US20030027256A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,301 US20020098506A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/032,990 US20030032060A1 (en) 1998-08-04 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,435 US6969758B2 (en) 1999-01-12 2001-12-27 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/033,246 US20020098505A1 (en) 1998-08-04 2001-12-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/081,056 US20040043927A1 (en) 1997-09-19 2002-02-20 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US10/119,480 US20040087769A1 (en) 1998-09-10 2002-04-09 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,040 US20030082759A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,042 US20030096386A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,046 US20030194791A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,051 US20030092147A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,047 US20030077778A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,041 US20030077776A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,059 US20030190721A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,045 US20030073210A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,044 US20030190717A1 (en) 1997-03-31 2002-04-11 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,043 US7220831B2 (en) 1997-03-31 2002-04-12 PRO235 polypeptides
US10/121,050 US20030054516A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,062 US20030077779A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,052 US20030199052A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,060 US20030190722A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,055 US20030190718A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,054 US20030199054A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,056 US20030082760A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,048 US20030199051A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,063 US20030199055A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,061 US20030082761A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,053 US20030199053A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,049 US20030022239A1 (en) 1997-06-18 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,058 US20030190720A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/121,057 US20030190719A1 (en) 1997-03-31 2002-04-12 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,154 US20030190724A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,157 US20030190725A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,213 US7193048B2 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,214 US7343721B2 (en) 1997-03-31 2002-04-15 PRO4406 polypeptide
US10/123,236 US20030068795A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,262 US20030049816A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,156 US20030194792A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,292 US20030073211A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,291 US20030199058A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,109 US20030190723A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,213 US20030199057A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,108 US7635478B2 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,212 US7276577B2 (en) 1997-03-31 2002-04-15 PRO1866 polypeptides
US10/123,771 US20030199060A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,261 US20030068796A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,322 US20030199059A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,235 US20030082762A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,155 US20030068794A1 (en) 1997-03-31 2002-04-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,215 US7291329B2 (en) 1997-03-31 2002-04-15 Antibodies against PRO4406
US10/123,905 US7285625B2 (en) 1997-06-18 2002-04-16 PRO536 polypeptides
US10/123,903 US20030073212A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,910 US7329404B2 (en) 1997-03-31 2002-04-16 Antibodies against PRO1310
US10/123,911 US7408032B2 (en) 1997-03-31 2002-04-16 PRO1188 polypeptides
US10/123,905 US20030087344A1 (en) 1997-06-18 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,907 US7084258B2 (en) 1997-03-31 2002-04-16 Antibodies against the PRO862 polypeptides
US10/123,904 US20030022328A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,908 US7335728B2 (en) 1997-03-31 2002-04-16 PRO1310 polypeptides
US10/123,909 US7193049B2 (en) 1997-03-31 2002-04-16 PRO862 polypeptides
US10/123,913 US20030203462A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,906 US20030190726A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,912 US20030100087A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/123,902 US20030077781A1 (en) 1997-03-31 2002-04-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,822 US7109305B2 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,816 US20030190728A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/125,805 US20030194794A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/125,704 US7357926B2 (en) 1997-03-31 2002-04-17 Antibodies against PRO1879 and the use thereof
US10/124,820 US20030190729A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,819 US7285626B2 (en) 1997-03-31 2002-04-17 PRO1076 polypeptides
US10/125,795 US7304131B2 (en) 1997-03-31 2002-04-17 PRO1483 polypeptides
US10/124,814 US7105335B2 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,818 US20030082763A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,817 US20030077786A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,823 US20030199062A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,824 US20030077659A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,821 US20030199023A1 (en) 1997-03-31 2002-04-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/124,813 US7312307B2 (en) 1997-03-31 2002-04-17 PRO1056 polypeptides
US10/125,927 US20030190731A1 (en) 1997-03-31 2002-04-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/125,924 US7342097B2 (en) 1997-03-31 2002-04-19 PRO1309 polypeptides
US10/125,931 US20030199063A1 (en) 1997-03-31 2002-04-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/125,922 US7309762B2 (en) 1997-03-31 2002-04-19 PRO1360 polypeptides
US10/125,932 US7317079B2 (en) 1997-03-31 2002-04-19 PRO812 polypeptides
US10/127,831 US20030082689A1 (en) 1997-03-31 2002-04-22 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/128,688 US7323544B2 (en) 1999-02-09 2002-04-23 PRO1434 polypeptides
US10/128,689 US20030087365A1 (en) 1997-03-31 2002-04-23 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/131,817 US7291701B2 (en) 1997-03-31 2002-04-24 PRO1777 polypeptides
US10/131,823 US7304132B2 (en) 1997-03-31 2002-04-24 PRO1693 polypeptides
US10/131,824 US7326413B2 (en) 1999-02-09 2002-04-24 Antibodies against the PRO1434 polypeptide
US10/131,825 US7282566B2 (en) 1997-03-31 2002-04-24 PRO1779 polypeptide
US10/131,815 US20030092103A1 (en) 1998-12-22 2002-04-24 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/137,865 US20030032155A1 (en) 1997-03-31 2002-05-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/137,867 US20030207349A1 (en) 1997-03-31 2002-05-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/137,868 US20030082764A1 (en) 1997-03-31 2002-05-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,024 US20040058424A1 (en) 1997-03-31 2002-05-06 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/139,963 US7288625B2 (en) 1997-03-31 2002-05-06 PRO4395 polypeptides
US10/139,980 US7247710B2 (en) 1997-03-31 2002-05-06 PRO4395 antibodies
US10/140,474 US20030032156A1 (en) 1997-03-31 2002-05-06 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,020 US20030207415A1 (en) 1997-03-31 2002-05-06 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,470 US20030022331A1 (en) 1997-03-31 2002-05-06 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,023 US20030207416A1 (en) 1997-03-31 2002-05-06 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,864 US20030207419A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,925 US20030073215A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,921 US7317080B2 (en) 1997-03-31 2002-05-07 PRO4303 polypeptides
US10/140,805 US20030207417A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,928 US20030068798A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,808 US7425621B2 (en) 1997-03-31 2002-05-07 Antibodies against the PRO4401 polypeptide
US10/140,860 US7307151B2 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,865 US20030207420A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/140,809 US20030207418A1 (en) 1997-03-31 2002-05-07 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/141,760 US7342104B2 (en) 1997-03-31 2002-05-08 Antibodies against the PRO4320 polypeptide
US10/141,754 US7361732B2 (en) 1997-03-31 2002-05-08 PRO4400 polypeptides
US10/141,701 US20030207421A1 (en) 1997-03-31 2002-05-08 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/141,756 US7488586B2 (en) 1997-03-31 2002-05-08 PRO4409 polypeptides
US10/141,755 US7297764B2 (en) 1997-03-31 2002-05-08 PRO4318 polypeptides
US10/142,417 US7304133B2 (en) 1997-03-31 2002-05-09 PRO4389 polypeptides
US10/142,430 US7309766B2 (en) 1997-03-31 2002-05-09 PRO5774 polypeptides
US10/142,425 US20030207424A1 (en) 1997-03-31 2002-05-09 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/143,113 US7329730B2 (en) 1997-03-31 2002-05-09 PRO4348 polypeptides
US10/143,114 US20030036180A1 (en) 1997-03-31 2002-05-09 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/142,431 US7285629B2 (en) 1997-03-31 2002-05-10 Pro5005 polypeptides
US10/142,423 US20030049817A1 (en) 1997-03-31 2002-05-10 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/143,032 US7408033B2 (en) 1997-03-31 2002-05-10 PRO5995 polypeptides
US10/142,419 US7153941B2 (en) 1997-03-31 2002-05-10 Antibodies that bind PRO4994 polypeptides
US10/146,730 US20030207427A1 (en) 1997-03-31 2002-05-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/146,792 US20030207428A1 (en) 1997-03-31 2002-05-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/147,528 US20030219885A1 (en) 1997-03-31 2002-05-16 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/147,498 US20030166091A1 (en) 1999-02-09 2002-05-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/147,519 US20030077791A1 (en) 1997-03-31 2002-05-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/147,536 US20040077064A1 (en) 1997-03-31 2002-05-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/147,492 US20030082765A1 (en) 1997-03-31 2002-05-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/152,373 US20030186367A1 (en) 1998-12-22 2002-05-20 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/152,395 US7189534B2 (en) 1997-03-31 2002-05-21 PRO4320 polynucleotide
US10/153,934 US20030129695A1 (en) 1997-03-31 2002-05-22 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/156,843 US20030207805A1 (en) 1997-06-18 2002-05-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/157,782 US20030077792A1 (en) 1997-03-31 2002-05-29 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/157,786 US20030208055A1 (en) 1997-03-31 2002-05-29 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/158,791 US20030207429A1 (en) 1997-03-31 2002-05-30 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/160,498 US20030073216A1 (en) 1997-03-31 2002-05-30 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/158,782 US20030082766A1 (en) 1997-03-31 2002-05-30 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,913 US20030022298A1 (en) 1997-09-15 2002-06-20 Secreted and transmembrane polypeptides and nucleic acids encoding the same
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AU2004237842A AU2004237842B2 (en) 1998-12-16 2004-12-10 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2004237920A AU2004237920B2 (en) 1998-12-16 2004-12-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2004237922A AU2004237922B2 (en) 1998-12-16 2004-12-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2004237923A AU2004237923B2 (en) 1998-12-16 2004-12-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2004237921A AU2004237921B2 (en) 1998-12-16 2004-12-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2004237919A AU2004237919B2 (en) 1998-12-16 2004-12-14 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/021,330 US20050159588A1 (en) 1999-06-02 2004-12-21 Compositions and methods for the diagnosis and treatment of tumor
US11/021,329 US20050159591A1 (en) 1999-06-02 2004-12-21 Compositions and methods for the diagnosis and treatment of tumor
US11/100,159 US7425613B2 (en) 1997-11-05 2005-04-05 PRO1375 polypeptides
JP2005229454A JP4145314B2 (en) 1999-06-02 2005-08-08 Compositions and methods for tumor cell growth inhibition
JP2005264293A JP2006068016A (en) 1999-12-01 2005-08-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/283,473 US20090142800A1 (en) 1998-08-04 2005-11-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/341,175 US7468427B2 (en) 1997-03-31 2006-01-27 Antibodies to PRO1275 polypeptide
JP2006225770A JP4072181B2 (en) 1999-06-02 2006-08-22 Compositions and methods for tumor cell growth inhibition
JP2006225772A JP2007029098A (en) 1999-06-02 2006-08-22 Method and composition for inhibiting neoplastic cell growth
JP2006225771A JP4074645B2 (en) 1999-06-02 2006-08-22 Compositions and methods for tumor cell growth inhibition
US11/538,754 US20070098634A1 (en) 1999-09-01 2006-10-04 Compositions and methods for the diagnosis and treatment of tumor
JP2007326424A JP2008167749A (en) 1999-12-01 2007-12-18 Secreted and transmembrane polypeptide and nucleic acid encoding the same
JP2007326613A JP2008161190A (en) 1999-12-01 2007-12-18 Secreted and transmembrane polypeptide and nucleic acid encoding the same
JP2007326609A JP2008148701A (en) 1999-12-01 2007-12-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2007325484A JP2008148699A (en) 1999-12-01 2007-12-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188580A IL188580A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188581A IL188581A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188577A IL188577A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188578A IL188578A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188576A IL188576A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL188579A IL188579A0 (en) 1998-12-16 2008-01-03 Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2008163394A JP2009039097A (en) 1999-03-08 2008-06-23 Composition and method for treatment of tumor
JP2008166460A JP2009000114A (en) 1999-03-08 2008-06-25 Composition and method for treating tumor
IL200883A IL200883A0 (en) 1998-12-16 2009-09-13 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL201001A IL201001A0 (en) 1998-12-16 2009-09-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL201030A IL201030A0 (en) 1998-12-16 2009-09-17 Secreted and transmembrane polypeptides and nucleic acids encoding the same

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US11285198P 1998-12-16 1998-12-16
US11314598P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11555899P 1999-01-12 1999-01-12
US11573399P 1999-01-12 1999-01-12
US11556599P 1999-01-12 1999-01-12
US60/115,565 1999-01-12
US60/115,733 1999-01-12
US60/115,558 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
USPCT/US99/12252 1999-06-22

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PCT/US1999/028551 Continuation-In-Part WO2000053750A1 (en) 1997-03-31 1999-12-02 Compositions and methods for the treatment of tumors
PCT/US2000/032678 Continuation-In-Part WO2001040466A2 (en) 1996-11-06 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/866,034 Continuation US20030170864A1 (en) 1996-11-06 2001-05-25 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/028,072 Continuation US20030004311A1 (en) 1997-03-31 2001-12-19 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/081,056 Continuation US20040043927A1 (en) 1997-09-19 2002-02-20 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US10/119,480 Continuation US20040087769A1 (en) 1998-09-10 2002-04-09 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/272,051 Continuation-In-Part US20030108544A1 (en) 1999-09-01 2002-10-16 Compositions and methods for the diagnosis and treatment of tumor

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