WO2000011183A3 - Chlamydia antigens and corresponding dna fragments and uses thereof - Google Patents

Chlamydia antigens and corresponding dna fragments and uses thereof Download PDF

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Publication number
WO2000011183A3
WO2000011183A3 PCT/IB1999/001449 IB9901449W WO0011183A3 WO 2000011183 A3 WO2000011183 A3 WO 2000011183A3 IB 9901449 W IB9901449 W IB 9901449W WO 0011183 A3 WO0011183 A3 WO 0011183A3
Authority
WO
WIPO (PCT)
Prior art keywords
cpn
dna fragments
corresponding dna
chlamydia
chlamydia antigens
Prior art date
Application number
PCT/IB1999/001449
Other languages
French (fr)
Other versions
WO2000011183A2 (en
Inventor
Andrew D Murdin
Raymond P Oomen
Original Assignee
Connaught Lab
Andrew D Murdin
Raymond P Oomen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Lab, Andrew D Murdin, Raymond P Oomen filed Critical Connaught Lab
Priority to EP99938465A priority Critical patent/EP1104470A2/en
Priority to CA002341637A priority patent/CA2341637A1/en
Priority to AU52973/99A priority patent/AU5297399A/en
Priority to JP2000566437A priority patent/JP2002523049A/en
Priority to MXPA01001639A priority patent/MXPA01001639A/en
Publication of WO2000011183A2 publication Critical patent/WO2000011183A2/en
Publication of WO2000011183A3 publication Critical patent/WO2000011183A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, containing a nucleotide sequence encoding any of the following polypeptides: CPN 100111, CPN 100224, CPN 100230, CPN 100231, CPN 100232, CPN 100235, CPN 100394, CPN 100395 of a strain of Chlamydia pneumoniae and a promoter to effect expression of any of the polypeptides in the host. Modifications are possible within the scope of this invention.
PCT/IB1999/001449 1998-08-20 1999-08-18 Chlamydia antigens and corresponding dna fragments and uses thereof WO2000011183A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP99938465A EP1104470A2 (en) 1998-08-20 1999-08-18 Chlamydia antigens and corresponding dna fragments and uses thereof
CA002341637A CA2341637A1 (en) 1998-08-20 1999-08-18 Chlamydia antigens and corresponding dna fragments and uses thereof
AU52973/99A AU5297399A (en) 1998-08-20 1999-08-18 (chlamydia) antigens and corresponding dna fragments and uses thereof
JP2000566437A JP2002523049A (en) 1998-08-20 1999-08-18 Chlamydia antigens and corresponding DNA fragments and uses thereof
MXPA01001639A MXPA01001639A (en) 1998-08-20 1999-08-18 Chlamydia.

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US9718898P 1998-08-20 1998-08-20
US9719798P 1998-08-20 1998-08-20
US9719598P 1998-08-20 1998-08-20
US9718798P 1998-08-20 1998-08-20
US9719698P 1998-08-20 1998-08-20
US9719098P 1998-08-20 1998-08-20
US9718998P 1998-08-20 1998-08-20
US60/097,197 1998-08-20
US60/097,190 1998-08-20
US60/097,189 1998-08-20
US60/097,195 1998-08-20
US60/097,187 1998-08-20
US60/097,196 1998-08-20
US60/097,188 1998-08-20
US9719198P 1998-08-27 1998-08-27
US60/097,191 1998-08-27
US37677099A 1999-08-17 1999-08-17
US09/376,770 1999-08-17

Publications (2)

Publication Number Publication Date
WO2000011183A2 WO2000011183A2 (en) 2000-03-02
WO2000011183A3 true WO2000011183A3 (en) 2000-06-08

Family

ID=27578413

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1999/001449 WO2000011183A2 (en) 1998-08-20 1999-08-18 Chlamydia antigens and corresponding dna fragments and uses thereof

Country Status (6)

Country Link
EP (1) EP1104470A2 (en)
JP (1) JP2002523049A (en)
AU (1) AU5297399A (en)
CA (1) CA2341637A1 (en)
MX (1) MXPA01001639A (en)
WO (1) WO2000011183A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1144642B1 (en) * 1998-12-08 2010-05-26 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
GB0203403D0 (en) 2002-02-13 2002-04-03 Chiron Spa Chlamydia cytotoxic-T cell epitopes
US7807802B2 (en) 2002-11-12 2010-10-05 Abbott Lab Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae
GB0709373D0 (en) * 2007-05-16 2007-06-27 Thrombosis Res Inst BCG-based anti-atheroma vaccine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0784059A1 (en) * 1994-09-20 1997-07-16 Hitachi Chemical Co., Ltd. Antigenic polypeptide of chlamydia pneumoniae
WO1998006408A1 (en) * 1996-08-14 1998-02-19 The Wistar Institute Of Anatomy And Biology Methods and compositions for preventing or retarding the development of atherosclerotic lesions
WO1999027105A2 (en) * 1997-11-21 1999-06-03 Genset Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0784059A1 (en) * 1994-09-20 1997-07-16 Hitachi Chemical Co., Ltd. Antigenic polypeptide of chlamydia pneumoniae
WO1998006408A1 (en) * 1996-08-14 1998-02-19 The Wistar Institute Of Anatomy And Biology Methods and compositions for preventing or retarding the development of atherosclerotic lesions
WO1999027105A2 (en) * 1997-11-21 1999-06-03 Genset Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection

Also Published As

Publication number Publication date
EP1104470A2 (en) 2001-06-06
AU5297399A (en) 2000-03-14
WO2000011183A2 (en) 2000-03-02
MXPA01001639A (en) 2004-09-06
JP2002523049A (en) 2002-07-30
CA2341637A1 (en) 2000-03-02

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