WO1998015287A1 - Vaccines - Google Patents
Vaccines Download PDFInfo
- Publication number
- WO1998015287A1 WO1998015287A1 PCT/EP1997/005578 EP9705578W WO9815287A1 WO 1998015287 A1 WO1998015287 A1 WO 1998015287A1 EP 9705578 W EP9705578 W EP 9705578W WO 9815287 A1 WO9815287 A1 WO 9815287A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antigen
- vaccine
- virus
- composition according
- alum
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/11011—Alpharetrovirus, e.g. avian leucosis virus
- C12N2740/11034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ334734A NZ334734A (en) | 1996-10-05 | 1997-09-30 | Vaccine composition comprising alum, a saponin fraction (QS21), a sterol (cholesterol), SUV (liposome forming) and MPL (3-de-O-acylated monophosphoryl lipid A) |
EP97910430A EP0939650A1 (en) | 1996-10-05 | 1997-09-30 | Vaccines |
JP10517196A JP2001501640A (en) | 1996-10-05 | 1997-09-30 | vaccine |
IL12898597A IL128985A0 (en) | 1996-10-05 | 1997-09-30 | Vaccines |
CZ991167A CZ116799A3 (en) | 1996-10-05 | 1997-09-30 | Adjuvant preparation and vaccine |
AU47812/97A AU714930B2 (en) | 1996-10-05 | 1997-09-30 | Vaccines |
BR9711853A BR9711853A (en) | 1996-10-05 | 1997-09-30 | Vaccines |
CA002267191A CA2267191A1 (en) | 1996-10-05 | 1997-09-30 | Vaccines |
NO991524A NO991524D0 (en) | 1996-10-05 | 1999-03-29 | vaccinations |
US13/162,134 US20110243971A1 (en) | 1995-04-25 | 2011-06-16 | Vaccines |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9620795.6 | 1996-10-05 | ||
GBGB9620795.6A GB9620795D0 (en) | 1996-10-05 | 1996-10-05 | Vaccines |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1996/001464 Continuation-In-Part WO1996033739A1 (en) | 1995-04-25 | 1996-04-01 | Vaccines containing a saponin and a sterol |
US94545097A Continuation-In-Part | 1995-04-25 | 1997-12-12 | |
US09269383 A-371-Of-International | 1999-04-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998015287A1 true WO1998015287A1 (en) | 1998-04-16 |
Family
ID=10800990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1997/005578 WO1998015287A1 (en) | 1995-04-25 | 1997-09-30 | Vaccines |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0939650A1 (en) |
JP (1) | JP2001501640A (en) |
KR (1) | KR20000048866A (en) |
CN (1) | CN1238696A (en) |
AR (1) | AR009958A1 (en) |
AU (1) | AU714930B2 (en) |
BR (1) | BR9711853A (en) |
CA (1) | CA2267191A1 (en) |
CO (1) | CO4910170A1 (en) |
CZ (1) | CZ116799A3 (en) |
GB (1) | GB9620795D0 (en) |
HU (1) | HUP9904549A3 (en) |
IL (1) | IL128985A0 (en) |
NO (1) | NO991524D0 (en) |
NZ (1) | NZ334734A (en) |
PL (1) | PL332633A1 (en) |
TR (1) | TR199900729T2 (en) |
WO (1) | WO1998015287A1 (en) |
ZA (1) | ZA978868B (en) |
Cited By (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999010008A1 (en) * | 1997-08-29 | 1999-03-04 | Aquila Biopharmaceuticals, Inc. | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient |
WO1999012565A1 (en) * | 1997-09-05 | 1999-03-18 | Smithkline Beecham Biologicals S.A. | Vaccines |
WO2000023105A2 (en) * | 1998-10-16 | 2000-04-27 | Smithkline Beecham Biologicals S.A. | Adjuvant systems and vaccines |
WO2001041802A1 (en) * | 1999-12-08 | 2001-06-14 | Statens Veterinärmedicinska Anstalt | Vaccine adjuvants comprising ginseng plant extract and added aluminium salt |
JP2002522397A (en) * | 1998-08-05 | 2002-07-23 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | Vaccine containing ISCOM consisting of sterol and saponin without other surfactants |
WO2002067983A1 (en) * | 2001-02-23 | 2002-09-06 | Glaxosmithkline Biologicals S.A. | Novel vaccine |
WO2002087614A2 (en) * | 2001-04-27 | 2002-11-07 | Glaxosmithkline Biologicals S.A. | Multivalent vaccine comprising an hiv antigen and an hsv antigen and/or an hpv antigen |
JP2002542204A (en) * | 1999-04-20 | 2002-12-10 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | Combination vaccine against Streptococcus pneumoniae and respiratory syncytial virus (RSV) |
JP2003508494A (en) * | 1999-09-07 | 2003-03-04 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | New composition |
US6544518B1 (en) | 1999-04-19 | 2003-04-08 | Smithkline Beecham Biologicals S.A. | Vaccines |
WO2003028760A2 (en) * | 2001-10-01 | 2003-04-10 | Glaxosmithkline Biologicals S.A. | Vaccine |
US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
US6572861B1 (en) | 1999-01-29 | 2003-06-03 | David S. Roberts | Adjuvants for use in vaccines |
WO2004084937A1 (en) * | 2003-03-24 | 2004-10-07 | Intercell Ag | Use of alum and a th1 immune response inducing adjuvant for enhancing immune responses |
JP2004532830A (en) * | 2001-02-23 | 2004-10-28 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | New vaccine |
US6905712B2 (en) | 1999-12-08 | 2005-06-14 | Statens Veterinarmedicinska Anstalt | Vaccine adjuvants comprising ginseng plant extract and added aluminum salt |
EP1741782A2 (en) | 2000-05-10 | 2007-01-10 | Sanofi Pasteur Limited | Immunogenic polypeptides encoded by MAGE minigenes and uses thereof |
WO2007071707A2 (en) | 2005-12-22 | 2007-06-28 | Glaxosmithkline Biologicals Sa | Pneumococcal polysaccharide conjugate vaccine |
WO2007068907A3 (en) * | 2005-12-13 | 2007-08-09 | Glaxosmithkline Biolog Sa | Vaccine compositions comprising a saponin adjuvant |
WO2007116028A2 (en) | 2006-04-07 | 2007-10-18 | Glaxosmithkline Biologicals S.A. | Conjugate vaccines |
US7378234B2 (en) | 2002-09-13 | 2008-05-27 | Intercell Ag | Method for isolating hepatitis C virus peptides |
WO2008063129A1 (en) * | 2006-11-20 | 2008-05-29 | Duecom | Use of lipid containing particles comprising quillaja saponins for the treatment of cancer |
EP1964573A2 (en) | 1999-10-22 | 2008-09-03 | Aventis Pasteur Limited | Method of inducing and/or enhancing an immune response to tumor antigens |
WO2008107370A1 (en) | 2007-03-02 | 2008-09-12 | Glaxosmithkline Biologicals S.A. | Novel method and compositions |
WO2009000826A1 (en) | 2007-06-26 | 2008-12-31 | Glaxosmithkline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
US7528223B2 (en) | 2002-07-24 | 2009-05-05 | Intercell Ag | Antigens encoded by alternative reading frames from pathogenic viruses |
EP2130921A2 (en) | 2004-08-05 | 2009-12-09 | GlaxoSmithKline Biologicals S.A. | Vaccine for prevention and treatment of HIV-infection |
WO2010023260A1 (en) | 2008-09-01 | 2010-03-04 | Glaxosmithkline Biologicals S.A. | Vaccine compositions |
US7704514B2 (en) | 2003-03-24 | 2010-04-27 | Intercell Ag | Vaccines |
WO2010082020A1 (en) | 2009-01-13 | 2010-07-22 | The Secretary Of State For Defence | Vaccine |
WO2010086614A1 (en) | 2009-01-29 | 2010-08-05 | The Secretary Of State For Defence | Treatment |
WO2010086617A2 (en) | 2009-01-29 | 2010-08-05 | The Secretary Of State For Defence | Treatment |
WO2010099580A1 (en) * | 2009-03-05 | 2010-09-10 | Jenny Colleen Mccloskey | Treatment of infection |
EP2266603A1 (en) | 2000-10-18 | 2010-12-29 | GlaxoSmithKline Biologicals S.A. | Tumour vaccines |
EP2277533A2 (en) | 2002-10-23 | 2011-01-26 | GlaxoSmithKline Biologicals s.a. | Methods for vaccinating against malaria |
WO2011015590A1 (en) | 2009-08-05 | 2011-02-10 | Glaxosmithkline Biologicals S.A. | Immunogenic composition comprising variants of staphylococcal clumping factor a |
EP2322211A1 (en) | 2005-02-17 | 2011-05-18 | GlaxoSmithKline Biologicals S.A. | Live attenuated rotavirus vaccine for oral administration |
WO2011117408A1 (en) | 2010-03-26 | 2011-09-29 | Glaxosmithkline Biologicals S.A. | Hiv vaccine |
WO2012038801A1 (en) | 2010-09-21 | 2012-03-29 | National Institute Of Immunology | A spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles |
WO2012041669A1 (en) | 2010-09-27 | 2012-04-05 | Crucell Holland B.V. | Heterologous prime boost vaccination regimen against malaria |
EP2476433A1 (en) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
US8323664B2 (en) | 2006-07-25 | 2012-12-04 | The Secretary Of State For Defence | Live vaccine strains of Francisella |
WO2013038156A1 (en) | 2011-09-16 | 2013-03-21 | Ucb Pharma S.A. | Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile |
US8425913B2 (en) | 2005-09-30 | 2013-04-23 | The Secretary Of State Of Defence | Immunogenic agents against Burkholderia pseudomallei and/or Burkholderia mallei, comprising lipopolysaccharide, capsular polysaccharide and/or proteins from Burkholderia pseudomallei |
WO2013074501A1 (en) | 2011-11-14 | 2013-05-23 | Crucell Holland B.V. | Heterologous prime-boost immunization using measles virus-based vaccines |
US8609108B2 (en) | 2009-04-14 | 2013-12-17 | The Secretary Of State For Defence | Gamma-glutamyl transpeptidase attenuated Francisella |
WO2015092710A1 (en) | 2013-12-19 | 2015-06-25 | Glaxosmithkline Biologicals, S.A. | Contralateral co-administration of vaccines |
US9066899B2 (en) | 2007-08-13 | 2015-06-30 | Glaxosmithkline Biologicals Sa | Vaccines |
US9279006B2 (en) | 2005-06-30 | 2016-03-08 | Glaxosmithkline Biologicals Sa | Anti-malaria vaccine |
US9364525B2 (en) | 2006-07-18 | 2016-06-14 | Glaxosmithkline Biologicals Sa | Vaccines for malaria |
EP3118213A1 (en) | 2007-12-19 | 2017-01-18 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Soluble forms of hendra and nipah virus f glycoprotein and uses thereof |
WO2018037045A1 (en) | 2016-08-23 | 2018-03-01 | Glaxosmithkline Biologicals Sa | Fusion peptides with antigens linked to short fragments of invariant chain (cd74) |
WO2018041891A1 (en) | 2016-09-01 | 2018-03-08 | Glaxosmithkline Biologicals Sa | Compositions |
WO2018060288A1 (en) | 2016-09-29 | 2018-04-05 | Glaxosmithkline Biologicals S.A. | Compositions and methods of treatment of persistent hpv infection |
WO2018104911A1 (en) | 2016-12-09 | 2018-06-14 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
WO2018104313A1 (en) * | 2016-12-07 | 2018-06-14 | Glaxosmithkline Biologicals Sa | Novel process |
WO2018219521A1 (en) * | 2017-05-30 | 2018-12-06 | Glaxosmithkline Biologicals S.A. | Methods for manufacturing an adjuvant |
US10149901B2 (en) | 2009-02-10 | 2018-12-11 | Seqirus UK Limited | Influenza vaccines with reduced amounts of squalene |
WO2019115817A2 (en) | 2017-12-15 | 2019-06-20 | Glaxosmithkline Biologicals Sa | Hepatitis b immunisation regimen and compositions |
WO2019115816A1 (en) | 2017-12-15 | 2019-06-20 | Glaxosmithkline Biologicals Sa | Hepatitis b immunisation regimen and compositions |
WO2019239311A1 (en) | 2018-06-12 | 2019-12-19 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
WO2020030572A1 (en) | 2018-08-07 | 2020-02-13 | Glaxosmithkline Biologicals Sa | Processes and vaccines |
WO2020128012A1 (en) | 2018-12-21 | 2020-06-25 | Glaxosmithkline Biologicals Sa | Methods of inducing an immune response |
WO2020178359A1 (en) | 2019-03-05 | 2020-09-10 | Glaxosmithkline Biologicals Sa | Hepatitis b immunisation regimen and compositions |
US10842867B2 (en) | 2005-11-04 | 2020-11-24 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0014139B1 (en) | 1999-09-24 | 2011-09-20 | derived from aromatic diamide or its salt, agricultural and horticultural composition, and, method for using an agricultural and horticultural composition. | |
NZ518999A (en) * | 1999-11-19 | 2002-12-20 | Csl Ltd | Vaccine compositions |
US20230109193A1 (en) * | 2021-10-02 | 2023-04-06 | Massachusetts Institute Of Technology | Synergistic Combination of Alum and Non-Liposome, Non-Micelle Particle Vaccine Adjuvants |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992006710A1 (en) * | 1990-10-23 | 1992-04-30 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn Volksgezondheid En Cultuur | Immunogenic complexes, in particular iscoms |
WO1993001831A1 (en) * | 1991-07-25 | 1993-02-04 | Idec Pharmaceuticals Corporation | Induction of cytotoxic t-lymphocyte responses |
WO1994022476A1 (en) * | 1993-03-29 | 1994-10-13 | Pfizer Inc. | Multicomponent clostridial vaccines using saponin adjuvants |
WO1996033739A1 (en) * | 1995-04-25 | 1996-10-31 | Smithkline Beecham Biologicals S.A. | Vaccines containing a saponin and a sterol |
-
1996
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1997
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- 1997-09-30 TR TR1999/00729T patent/TR199900729T2/en unknown
- 1997-09-30 BR BR9711853A patent/BR9711853A/en not_active Application Discontinuation
- 1997-09-30 CN CN97180166A patent/CN1238696A/en active Pending
- 1997-09-30 JP JP10517196A patent/JP2001501640A/en active Pending
- 1997-09-30 CA CA002267191A patent/CA2267191A1/en not_active Abandoned
- 1997-09-30 EP EP97910430A patent/EP0939650A1/en not_active Withdrawn
- 1997-09-30 PL PL97332633A patent/PL332633A1/en unknown
- 1997-09-30 HU HU9904549A patent/HUP9904549A3/en unknown
- 1997-09-30 AU AU47812/97A patent/AU714930B2/en not_active Ceased
- 1997-09-30 NZ NZ334734A patent/NZ334734A/en unknown
- 1997-09-30 KR KR1019990702874A patent/KR20000048866A/en not_active Application Discontinuation
- 1997-09-30 CZ CZ991167A patent/CZ116799A3/en unknown
- 1997-09-30 IL IL12898597A patent/IL128985A0/en unknown
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Also Published As
Publication number | Publication date |
---|---|
CO4910170A1 (en) | 2000-04-24 |
CN1238696A (en) | 1999-12-15 |
EP0939650A1 (en) | 1999-09-08 |
JP2001501640A (en) | 2001-02-06 |
NZ334734A (en) | 2000-05-26 |
AU4781297A (en) | 1998-05-05 |
ZA978868B (en) | 1999-04-06 |
HU9904549A (en) | 2000-05-28 |
NO991524L (en) | 1999-03-29 |
NO991524D0 (en) | 1999-03-29 |
AR009958A1 (en) | 2000-05-17 |
CZ116799A3 (en) | 1999-08-11 |
KR20000048866A (en) | 2000-07-25 |
AU714930B2 (en) | 2000-01-13 |
PL332633A1 (en) | 1999-09-27 |
BR9711853A (en) | 1999-08-24 |
TR199900729T2 (en) | 1999-07-21 |
HUP9904549A3 (en) | 2001-06-28 |
IL128985A0 (en) | 2000-02-17 |
GB9620795D0 (en) | 1996-11-20 |
CA2267191A1 (en) | 1998-04-16 |
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