WO1997005899A3 - Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same - Google Patents

Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same Download PDF

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Publication number
WO1997005899A3
WO1997005899A3 PCT/CA1996/000526 CA9600526W WO9705899A3 WO 1997005899 A3 WO1997005899 A3 WO 1997005899A3 CA 9600526 W CA9600526 W CA 9600526W WO 9705899 A3 WO9705899 A3 WO 9705899A3
Authority
WO
WIPO (PCT)
Prior art keywords
microorganisms
methods
pharmaceutical compositions
membrane vesicles
preparing same
Prior art date
Application number
PCT/CA1996/000526
Other languages
French (fr)
Other versions
WO1997005899A2 (en
Inventor
Jagath L Kadurugamuwa
Terry J Beveridge
Original Assignee
Univ Guelph
Jagath L Kadurugamuwa
Terry J Beveridge
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Guelph, Jagath L Kadurugamuwa, Terry J Beveridge filed Critical Univ Guelph
Priority to BR9609882A priority Critical patent/BR9609882A/en
Priority to AU66095/96A priority patent/AU707131B2/en
Priority to EP96925628A priority patent/EP0841944A2/en
Publication of WO1997005899A2 publication Critical patent/WO1997005899A2/en
Publication of WO1997005899A3 publication Critical patent/WO1997005899A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6006—Cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, methods for preparing same, and their use in the prevention and treatment of infectious diseases.
PCT/CA1996/000526 1995-08-04 1996-08-02 Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same WO1997005899A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BR9609882A BR9609882A (en) 1995-08-04 1996-08-02 Vaccine processes to prepare the same to treat an infectious disease to insert a nucleic acid molecule into a labeling cell to administer a therapeutic agent to a host and to screen an immunogenic antigen of a pathogen using a membrane vesicle pharmaceutical composition system of drug release and membrane vesicle
AU66095/96A AU707131B2 (en) 1995-08-04 1996-08-02 Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same
EP96925628A EP0841944A2 (en) 1995-08-04 1996-08-02 Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US190395P 1995-08-04 1995-08-04
US60/001,903 1995-08-04

Publications (2)

Publication Number Publication Date
WO1997005899A2 WO1997005899A2 (en) 1997-02-20
WO1997005899A3 true WO1997005899A3 (en) 1997-05-29

Family

ID=21698360

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA1996/000526 WO1997005899A2 (en) 1995-08-04 1996-08-02 Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same

Country Status (5)

Country Link
EP (1) EP0841944A2 (en)
AU (1) AU707131B2 (en)
BR (1) BR9609882A (en)
CA (1) CA2182637A1 (en)
WO (1) WO1997005899A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918319D0 (en) * 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB0103171D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
WO2003084508A1 (en) * 2002-04-04 2003-10-16 Applied Nanosystems B.V. Delivery of a substance to a pre-determined site
EP1350507A1 (en) * 2002-04-04 2003-10-08 Applied NanoSystems B.V. Delivery of a substance to a pre-determinated site
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
FR2859218A1 (en) * 2003-08-25 2005-03-04 Centre Nat Rech Scient Microvesicles made from the outer membrane of bacteria, useful e.g. as vectors for therapeutic agents, include a detectable signature, preferably fluorescent, to facilitate visualization
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
WO2009130649A2 (en) * 2008-04-21 2009-10-29 Nanoxis Ab Plasma membrane vesicles and methods of making and using same
WO2011027956A2 (en) 2009-09-04 2011-03-10 주식회사이언메딕스 Extracellular vesicles derived from gram-positive bacteria, and disease model using same
KR101430283B1 (en) 2009-09-01 2014-08-14 주식회사이언메딕스 Extracellular vesicles derived from gut microbiota, and disease models, vaccines, drug screening methods, and diagnostic methods using the same
EP2632483A2 (en) * 2010-10-27 2013-09-04 GlaxoSmithKline Biologicals S.A. Immunogenic composition
EP3068426B1 (en) 2013-11-13 2020-02-12 University Of Oslo Outer membrane vesicles and uses thereof
US20220378902A1 (en) * 2019-08-22 2022-12-01 Sichuan University Bacterial membrane vesicles, and separation and preparation system and method therefor
CN114364396B (en) * 2019-08-22 2024-01-23 四川大学 Application of pseudomonas aeruginosa vaccine in burn and scald infection resistance
CN112402601B (en) * 2019-08-22 2022-09-13 四川大学 Staphylococcus aureus membrane vesicle and preparation method and application thereof
CN112410240B (en) * 2019-08-22 2022-10-18 四川大学 Pseudomonas aeruginosa membrane vesicle and preparation method and application thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006696A2 (en) * 1988-12-19 1990-06-28 Praxis Biologics, Inc. Meningococcal class 1 outer-membrane protein vaccine
WO1991011174A1 (en) * 1990-01-25 1991-08-08 The University Of Colorado Foundation, Inc. Method for preventing immune suppression in trauma patients
SU1708351A1 (en) * 1990-02-05 1992-01-30 Научно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи Shigella sonnei bacterial strain useable for preparing vital vaccine against sonne dysentery
WO1992005194A1 (en) * 1990-09-25 1992-04-02 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Vaccine suitable for combatting bordetella pertussis
EP0564689A1 (en) * 1992-04-10 1993-10-13 SCHWEIZERISCHES SERUM- & IMPFINSTITUT BERN Recombinant live vaccines against Gram-negative enteric pathogens
WO1993022423A1 (en) * 1992-04-29 1993-11-11 Microcarb Inc. Nutrient phospholipids for pathogenic bacteria
WO1994004677A1 (en) * 1992-08-13 1994-03-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services The use of cd4 plasma membrane vesicles (pmv) as a therapeutic agent for aids
WO1994008021A1 (en) * 1992-10-02 1994-04-14 De Staat Der Nederlanden, Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Immunogenic meningococcal lps and outer membrane vesicles and vaccine therefrom

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006696A2 (en) * 1988-12-19 1990-06-28 Praxis Biologics, Inc. Meningococcal class 1 outer-membrane protein vaccine
WO1991011174A1 (en) * 1990-01-25 1991-08-08 The University Of Colorado Foundation, Inc. Method for preventing immune suppression in trauma patients
SU1708351A1 (en) * 1990-02-05 1992-01-30 Научно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи Shigella sonnei bacterial strain useable for preparing vital vaccine against sonne dysentery
WO1992005194A1 (en) * 1990-09-25 1992-04-02 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Vaccine suitable for combatting bordetella pertussis
EP0564689A1 (en) * 1992-04-10 1993-10-13 SCHWEIZERISCHES SERUM- & IMPFINSTITUT BERN Recombinant live vaccines against Gram-negative enteric pathogens
WO1993022423A1 (en) * 1992-04-29 1993-11-11 Microcarb Inc. Nutrient phospholipids for pathogenic bacteria
WO1994004677A1 (en) * 1992-08-13 1994-03-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services The use of cd4 plasma membrane vesicles (pmv) as a therapeutic agent for aids
WO1994008021A1 (en) * 1992-10-02 1994-04-14 De Staat Der Nederlanden, Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Immunogenic meningococcal lps and outer membrane vesicles and vaccine therefrom

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 6800, Derwent World Patents Index; AN 66-31154f, XP002018267 *
DATABASE WPI Week 9320, Derwent World Patents Index; AN 93-165271, XP002018268 *

Also Published As

Publication number Publication date
AU6609596A (en) 1997-03-05
CA2182637A1 (en) 1997-02-05
BR9609882A (en) 1999-07-27
AU707131B2 (en) 1999-07-01
EP0841944A2 (en) 1998-05-20
WO1997005899A2 (en) 1997-02-20

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