WO1994003500A1 - Glucans with immunostimulant activity - Google Patents
Glucans with immunostimulant activity Download PDFInfo
- Publication number
- WO1994003500A1 WO1994003500A1 PCT/EP1993/002063 EP9302063W WO9403500A1 WO 1994003500 A1 WO1994003500 A1 WO 1994003500A1 EP 9302063 W EP9302063 W EP 9302063W WO 9403500 A1 WO9403500 A1 WO 9403500A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- glucans
- glucan
- activity
- obtainable
- mouse
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU47063/93A AU4706393A (en) | 1992-08-10 | 1993-08-03 | Glucans with immunostimulant activity |
EP93917731A EP0654047A1 (en) | 1992-08-10 | 1993-08-03 | Glucans with immunostimulant activity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921967A IT1256035B (en) | 1992-08-10 | 1992-08-10 | IMMUNOSTIMULATING ACTIVITY GLUCANS |
ITMI92A001967 | 1992-08-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1994003500A1 true WO1994003500A1 (en) | 1994-02-17 |
Family
ID=11363857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1993/002063 WO1994003500A1 (en) | 1992-08-10 | 1993-08-03 | Glucans with immunostimulant activity |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0654047A1 (en) |
CN (1) | CN1082056A (en) |
AU (1) | AU4706393A (en) |
IT (1) | IT1256035B (en) |
MX (1) | MX9304793A (en) |
WO (1) | WO1994003500A1 (en) |
ZA (1) | ZA935730B (en) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2728269A1 (en) * | 1994-12-20 | 1996-06-21 | Inst Francais Du Petrole | PROCESS FOR TREATING A FERMENTATION MUST CONTAINING POLYSACCHARIDE |
US5532223A (en) * | 1989-09-08 | 1996-07-02 | Alpha-Beta Technology, Inc. | Use of aqueous soluble glucan preparations to stimulate platelet production |
US5622939A (en) * | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
US5633369A (en) * | 1989-09-08 | 1997-05-27 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
EP0819762A2 (en) * | 1996-07-19 | 1998-01-21 | Mibelle AG Cosmetics | Process for the isolation of glucan from yeast |
US5849720A (en) * | 1989-09-08 | 1998-12-15 | Alpha-Beta Technology, Inc. | Enhancement of non-specific immune defenses by administration of underivatized, aqueous soluble glucans |
US6046323A (en) * | 1997-07-29 | 2000-04-04 | The Collaborative Group, Ltd. | Conformations of PPG-glucan |
US6369216B1 (en) | 1998-09-25 | 2002-04-09 | Biopolymer Engineering Pharmaceutical, Inc. | Very high molecular weight β-glucans |
WO2002012348A3 (en) * | 2000-08-03 | 2002-04-25 | Merck Patent Gmbh | Isolation of glucan particles and uses thereof |
WO2005067977A1 (en) * | 2004-01-14 | 2005-07-28 | Pleuran, S.R.O. | Method of preparation of a fungal glucane hydrogel having antibacterial and immunostimulant activity, and use thereof |
US7022685B2 (en) | 1998-09-25 | 2006-04-04 | Biopolymer Engineering, Inc. | Very high molecular weight β-glucans |
US8563531B2 (en) | 2002-08-13 | 2013-10-22 | Biothera, Inc. | Methods of using beta glucan as a radioprotective agent |
US8883760B2 (en) | 2002-09-04 | 2014-11-11 | University Of Louisville Research Foundation, Inc. | Cancer therapy using beta glucan and antibodies |
WO2022172087A1 (en) * | 2021-02-14 | 2022-08-18 | Universidade Catolica Portuguesa-Ucp | Yeast glucans, methods and uses thereof |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7507724B2 (en) * | 2001-01-16 | 2009-03-24 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
CN101117356B (en) * | 2007-09-17 | 2010-06-09 | 中国农业大学 | Method for preparing water-insoluble beta-1,3/1,6-dextran |
CN101885784B (en) * | 2010-07-20 | 2012-08-08 | 三峡大学 | Method for producing glucomannan by liquid culture of konjac cells |
CN105907714A (en) * | 2016-04-28 | 2016-08-31 | 王晓冰 | Improved method for cultivating NK (natural killer) cells |
WO2020034948A1 (en) * | 2018-08-13 | 2020-02-20 | Lifenergy Biotech Corp. | Method for in vitro activation of immune cells |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4992540A (en) * | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
EP0416343A2 (en) * | 1989-09-04 | 1991-03-13 | Consiglio Nazionale Delle Ricerche | Process for preparing a glucane-containing product starting from candida albicans BMM-12 |
WO1991003495A1 (en) * | 1989-09-08 | 1991-03-21 | Alpha Beta Technology, Inc. | Method for producing soluble glucans |
-
1992
- 1992-08-10 IT ITMI921967A patent/IT1256035B/en active IP Right Grant
-
1993
- 1993-08-03 AU AU47063/93A patent/AU4706393A/en not_active Abandoned
- 1993-08-03 EP EP93917731A patent/EP0654047A1/en not_active Withdrawn
- 1993-08-03 WO PCT/EP1993/002063 patent/WO1994003500A1/en not_active Application Discontinuation
- 1993-08-06 ZA ZA935730A patent/ZA935730B/en unknown
- 1993-08-06 CN CN93109362A patent/CN1082056A/en active Pending
- 1993-08-06 MX MX9304793A patent/MX9304793A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4992540A (en) * | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
EP0416343A2 (en) * | 1989-09-04 | 1991-03-13 | Consiglio Nazionale Delle Ricerche | Process for preparing a glucane-containing product starting from candida albicans BMM-12 |
WO1991003495A1 (en) * | 1989-09-08 | 1991-03-21 | Alpha Beta Technology, Inc. | Method for producing soluble glucans |
Cited By (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5532223A (en) * | 1989-09-08 | 1996-07-02 | Alpha-Beta Technology, Inc. | Use of aqueous soluble glucan preparations to stimulate platelet production |
US5633369A (en) * | 1989-09-08 | 1997-05-27 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
US5663324A (en) * | 1989-09-08 | 1997-09-02 | Alpha-Beta Technology, Inc. | Method for producing underivatized, aqueous soluble β(1-3) glucan |
US5849720A (en) * | 1989-09-08 | 1998-12-15 | Alpha-Beta Technology, Inc. | Enhancement of non-specific immune defenses by administration of underivatized, aqueous soluble glucans |
US5811542A (en) * | 1989-09-08 | 1998-09-22 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
US5817643A (en) * | 1992-08-21 | 1998-10-06 | Alpha-Beta Technology, Inc. | Underivatized, aqueous soluable β(1-3) glucan, composition and method of making same |
US5622939A (en) * | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
US5783569A (en) * | 1992-08-21 | 1998-07-21 | Alpha-Beta Technology, Inc. | Uses for underivatized, aqueous soluble β(1-3) glucan and compositions comprising same |
FR2728269A1 (en) * | 1994-12-20 | 1996-06-21 | Inst Francais Du Petrole | PROCESS FOR TREATING A FERMENTATION MUST CONTAINING POLYSACCHARIDE |
EP0819762A3 (en) * | 1996-07-19 | 2001-09-05 | Mibelle AG Cosmetics | Process for the isolation of glucan from yeast |
EP0819762A2 (en) * | 1996-07-19 | 1998-01-21 | Mibelle AG Cosmetics | Process for the isolation of glucan from yeast |
DE19629118C2 (en) * | 1996-07-19 | 2001-11-29 | Mibelle Ag Cosmetics Buchs | Process for isolating glucan from yeast |
DE19629118A1 (en) * | 1996-07-19 | 1998-01-22 | Mibelle Ag Cosmetics | Process for isolating glucan from yeast |
US6046323A (en) * | 1997-07-29 | 2000-04-04 | The Collaborative Group, Ltd. | Conformations of PPG-glucan |
US6369216B1 (en) | 1998-09-25 | 2002-04-09 | Biopolymer Engineering Pharmaceutical, Inc. | Very high molecular weight β-glucans |
US7022685B2 (en) | 1998-09-25 | 2006-04-04 | Biopolymer Engineering, Inc. | Very high molecular weight β-glucans |
US7566704B2 (en) | 1998-09-25 | 2009-07-28 | Biopolymer Engineering, Inc. | Very high molecular weight β-glucans |
US9187575B2 (en) | 2000-08-03 | 2015-11-17 | Abac R&D Ag | Isolation of glucan particles and uses thereof |
WO2002012348A3 (en) * | 2000-08-03 | 2002-04-25 | Merck Patent Gmbh | Isolation of glucan particles and uses thereof |
US8563531B2 (en) | 2002-08-13 | 2013-10-22 | Biothera, Inc. | Methods of using beta glucan as a radioprotective agent |
US9522187B2 (en) | 2002-09-04 | 2016-12-20 | University Of Louisville Research Foundation, Inc. | Cancer therapy using beta glucan and antibodies |
US8883760B2 (en) | 2002-09-04 | 2014-11-11 | University Of Louisville Research Foundation, Inc. | Cancer therapy using beta glucan and antibodies |
WO2005067977A1 (en) * | 2004-01-14 | 2005-07-28 | Pleuran, S.R.O. | Method of preparation of a fungal glucane hydrogel having antibacterial and immunostimulant activity, and use thereof |
US7622459B2 (en) | 2004-01-14 | 2009-11-24 | Pleuran SRO | Method of preparation of a fungal glucane hydrogel having antibacterial and immunostimulant activity, and use thereof |
WO2022172087A1 (en) * | 2021-02-14 | 2022-08-18 | Universidade Catolica Portuguesa-Ucp | Yeast glucans, methods and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
EP0654047A1 (en) | 1995-05-24 |
ITMI921967A1 (en) | 1994-02-10 |
ZA935730B (en) | 1994-03-03 |
CN1082056A (en) | 1994-02-16 |
IT1256035B (en) | 1995-11-21 |
ITMI921967A0 (en) | 1992-08-10 |
MX9304793A (en) | 1994-05-31 |
AU4706393A (en) | 1994-03-03 |
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