WO1990002526A1 - Screw - Google Patents
Screw Download PDFInfo
- Publication number
- WO1990002526A1 WO1990002526A1 PCT/AU1989/000386 AU8900386W WO9002526A1 WO 1990002526 A1 WO1990002526 A1 WO 1990002526A1 AU 8900386 W AU8900386 W AU 8900386W WO 9002526 A1 WO9002526 A1 WO 9002526A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- screw
- region
- thread
- bone
- pedicle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/8625—Shanks, i.e. parts contacting bone tissue
- A61B17/863—Shanks, i.e. parts contacting bone tissue with thread interrupted or changing its form along shank, other than constant taper
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3085—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface
- A61F2002/30861—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface having threads of increasing or decreasing height
Definitions
- the present invention relates to a screw having a multi-thread profile adapted for insertion into bone, and in particular, into a vertebra. Following fracture of a bone it is necessary to immobilise the fractured bone, or limb, to allow the bone fragments to heal. In some cases, in particular in fractures of the spine, this is achieved using a fixation system comprising screws and a supporting plate or rod. In the case of a spinal fracture this fixation system is used to immobolise one or more spinal segments till a bone graft placed around the segment to be immobilised gains sufficient strength to immobilise the segment.
- the fixation system requires anchorage points above and below the segment to be fused to which are attached longitudinal bars or plates providing the longitudinal stability.
- the screws are typically referred to as pedicle screws as they are passed through the pedicle of the vertebra.
- pedicle screws are set in a hole drilled down through the pedicle into the centrum or body of the vertebra.
- the pedicle is the solid narrow bone adjoining the centrum which supports the neural arch.
- the centrum is composed of a type of bone called concellou ⁇ . Cancellous bone is crumbly, peppered with small voids, and not very strong.
- the pedicle screw In the case of a spinal fracture, the pedicle screw is expected to maintain a high degree of anchorage in the supporting vertebra irrespective of the applied stress conditions. It must be resilient and strong enough to withstand the effects of both static and dynamic loading on the spine and not fracture or fail. The body of the screw, especially the upper portion needs, therefore, to be as broad as possible to maximise strength. However, as the major thread diameter of the screw must be significantly less than the diameter of the pedicle at its narrowest point, a shallow thread profile is obligatory. As a consequence of the somewhat mutually exclusive requirements of maximum screw strength and preservation of pedicle integrity, prior art pedicle screws typically have a uniformly wide body with a low thread profile to minimise the major diameter of the screw.
- the present inventors have designed a novel screw of relatively uniform major thread diameter with distinct segments of different thread profiles.
- the present invention consists in a screw adapted for insertion into a bone, the screw being characterised in that the screw is divided into at least two distinct regions, the depth of the screw thread in each region being different to that in each other region, whilst the overall diameter of the screw is substantially constant over the length of the screw.
- the screw is divided into two distinct regions.
- the depth of the screw thread in the region proximate the head of the screw is less than the depth of the screw thread in the region remote from the screw head.
- the screw is adapted for insertion into a vertebra through its pedicle.
- the upper face of the screw is substantially perpendicular to the base of the screw. As will be recognised by persons skilled in the art such an arrangement results in the screw having greater resistance to extraction.
- Figure 1 shows a longitudinal cross-section of the screw of the present invention
- Figure 2 shows an expanded cross-sectional view of the screw thread of the upper region of the screw shown in Fig. 1;
- FIG. 3 shows an expanded cross-sectional view of the screw thread of the lower region of the screw shown in Fig. 1.
- the screw 10 comprises a head 12 (detail not shown) and a body portion 14.
- the body portion is divided into two distinct regions 16 and 18, with region 16 being proximate screw head 12.
- region 16 being proximate screw head 12.
- the depth of the screw thread 20 in region 16 is less than the depth of the screw thread 22 in region 18, whilst the diameter of the base 24 in region 16 is greater than the diameter of the base 26 in region 18. This results in the overall diameter of the screw is substantially constant over the entire length of the screw.
- the segment of the screw contacting the pedicle retains maximum strength by employing a low thread profile on a high diameter base, whilst the segment of the screw contacting the centrum maximises stability by the use of a thread profile which is as deep as possible to obtain optimum anchorage in this type of bone on a low (narrow) diameter base.
- This screw therefore provides firmer anchorage in the vertebal body without sacrificing strength through the use of a wide base - low thread profile in its upper region which will be in the pedicle, and a narrow base - high thread profile in the lower half of the shaft which will be in the cancellous bone of the centrum.
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
The present invention discloses a screw (10) adapted for insertion into a bone and in particular a vertebra. The screw (10) is divided into two distinct regions (16 and 18) with the depth of the screw thread (20, 22) in each region being different to that in each other region whilst the overall diameter of the screw (10) is substantially constant over the length of the screw (10).
Description
SCREW
Field of the Invention
The present invention relates to a screw having a multi-thread profile adapted for insertion into bone, and in particular, into a vertebra. Following fracture of a bone it is necessary to immobilise the fractured bone, or limb, to allow the bone fragments to heal. In some cases, in particular in fractures of the spine, this is achieved using a fixation system comprising screws and a supporting plate or rod. In the case of a spinal fracture this fixation system is used to immobolise one or more spinal segments till a bone graft placed around the segment to be immobilised gains sufficient strength to immobilise the segment.
The fixation system requires anchorage points above and below the segment to be fused to which are attached longitudinal bars or plates providing the longitudinal stability. In the case of a spinal fracture the screws are typically referred to as pedicle screws as they are passed through the pedicle of the vertebra. Each pedicle screw is set in a hole drilled down through the pedicle into the centrum or body of the vertebra. The pedicle is the solid narrow bone adjoining the centrum which supports the neural arch. The centrum is composed of a type of bone called concellouε. Cancellous bone is crumbly, peppered with small voids, and not very strong.
In the case of a spinal fracture, the pedicle screw is expected to maintain a high degree of anchorage in the supporting vertebra irrespective of the applied stress conditions. It must be resilient and strong enough to withstand the effects of both static and dynamic loading on the spine and not fracture or fail. The body of the screw, especially the upper portion needs, therefore, to be as broad as possible to maximise strength. However, as the major thread diameter of the screw must be significantly less than the diameter of the pedicle at its
narrowest point, a shallow thread profile is obligatory. As a consequence of the somewhat mutually exclusive requirements of maximum screw strength and preservation of pedicle integrity, prior art pedicle screws typically have a uniformly wide body with a low thread profile to minimise the major diameter of the screw. As a result of using uniformly low thread profile, existing pedicle screws are liable to fail through extraction, as they may be pulled out of the crumbly cancellous bone when subjected to stress applied under extreme loading. They are, therefore, suspect means of support and/or stability for use in a spinal fracture fixation system.
As strength and stability are major operational factors, the present inventors have designed a novel screw of relatively uniform major thread diameter with distinct segments of different thread profiles.
Accordingly, the present invention consists in a screw adapted for insertion into a bone, the screw being characterised in that the screw is divided into at least two distinct regions, the depth of the screw thread in each region being different to that in each other region, whilst the overall diameter of the screw is substantially constant over the length of the screw.
In a preferred embodiment of the present invention the screw is divided into two distinct regions.
In a further preferred embodiment of the present invention the depth of the screw thread in the region proximate the head of the screw is less than the depth of the screw thread in the region remote from the screw head. In yet a further preferred embodiment of the present invention the screw is adapted for insertion into a vertebra through its pedicle.
It is presently preferred that the upper face of the screw is substantially perpendicular to the base of the screw. As will be recognised by persons skilled in the
art such an arrangement results in the screw having greater resistance to extraction.
In order that the nature of the present invention may be more clearly understood a preferred form thereof will now be described with reference to the accompanying drawings, in whic :-
Figure 1 shows a longitudinal cross-section of the screw of the present invention;
Figure 2 shows an expanded cross-sectional view of the screw thread of the upper region of the screw shown in Fig. 1; and
Figure 3 shows an expanded cross-sectional view of the screw thread of the lower region of the screw shown in Fig. 1. As shown in Figure 1 the screw 10 comprises a head 12 (detail not shown) and a body portion 14. The body portion is divided into two distinct regions 16 and 18, with region 16 being proximate screw head 12. As can clearly be seen in this drawing the depth of the screw thread 20 in region 16 is less than the depth of the screw thread 22 in region 18, whilst the diameter of the base 24 in region 16 is greater than the diameter of the base 26 in region 18. This results in the overall diameter of the screw is substantially constant over the entire length of the screw.
As is best shown in Figs. 2 and 3 the upper face of screw threads 20 and 22 are perpendicular to bases 24 and 26 respectively.
As will be readily apparent to persons skilled in the art, when the screw of the present invention is adapted for insertion into a vertebra the segment of the screw contacting the pedicle retains maximum strength by employing a low thread profile on a high diameter base, whilst the segment of the screw contacting the centrum maximises stability by the use of a thread profile which
is as deep as possible to obtain optimum anchorage in this type of bone on a low (narrow) diameter base.
This screw therefore provides firmer anchorage in the vertebal body without sacrificing strength through the use of a wide base - low thread profile in its upper region which will be in the pedicle, and a narrow base - high thread profile in the lower half of the shaft which will be in the cancellous bone of the centrum.
From the foregoing description, it should be apparent that the invention encompasses an advantageous advance in the art. Further, it should be clear that the invention may be embodiment in other specific forms without departing from the spirit of the essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive.
Claims
1. A screw adapted for insertion into a bone, the screw being characterised in that the screw is divided into at least two distinct regions, the depth of the screw thread in each region being different to that in each other region, whilst the overall diameter of the screw is substantially constant over the length of the screw.
2. A screw as claimed in claim 1 in which the screw is divided into two distinct regions.
3. A screw as claimed in claim 1 or claim 2 in which the depth of the screw thread in the region proximate the screw head is less than the depth of the screw thread in the region remote from the screw head.
4. A screw as claimed in any one of claims 1 to 3 in which the screw is adapted for insertion into a vertebra through its pedicle.
5. A screw substantially as hereinbefore described with reference to the accompanying drawing.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ035188 | 1988-09-09 | ||
AUPJ0351 | 1988-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1990002526A1 true WO1990002526A1 (en) | 1990-03-22 |
Family
ID=3773358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AU1989/000386 WO1990002526A1 (en) | 1988-09-09 | 1989-09-11 | Screw |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO1990002526A1 (en) |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0472017A1 (en) * | 1990-08-24 | 1992-02-26 | Anton Prof. Dr. Härle | Cylindrical bodies with external thread |
EP0491211A1 (en) * | 1990-12-19 | 1992-06-24 | Synthes AG, Chur | Bone screw |
US5147363A (en) * | 1989-12-21 | 1992-09-15 | Haerle Anton | Screw for use in osteosynthesis |
FR2739151A1 (en) * | 1995-09-22 | 1997-03-28 | Numedic | Fixing screw for bone implants |
US5964768A (en) * | 1993-01-21 | 1999-10-12 | Acumed, Inc. | Tapered bone screw with continuously varying pitch |
US6030162A (en) * | 1998-12-18 | 2000-02-29 | Acumed, Inc. | Axial tension screw |
WO2000032125A1 (en) * | 1998-11-26 | 2000-06-08 | Synthes Ag Chur | Screw |
US6299615B1 (en) | 1993-01-21 | 2001-10-09 | Acumed, Inc. | System for fusing joints |
US6468277B1 (en) | 2000-04-04 | 2002-10-22 | Ethicon, Inc. | Orthopedic screw and method |
EP1393689A2 (en) * | 1997-02-11 | 2004-03-03 | MICHELSON, Gary Karlin | Anterior cervical plating system and bone screw |
WO2004086991A1 (en) | 2003-04-03 | 2004-10-14 | Stratec Medical Ag | Bone screw |
GB2406056A (en) * | 2003-09-17 | 2005-03-23 | Corin Ltd | Bone tapping kit, fixation member and prosthetic cup |
US6875215B2 (en) * | 2002-02-15 | 2005-04-05 | John Stanley Taras | Distraction pin for fracture fixation |
WO2005058175A1 (en) | 2003-12-19 | 2005-06-30 | Depuy International Limited | A bone screw |
US6916320B2 (en) | 1997-02-11 | 2005-07-12 | Gary K. Michelson | Anterior cervical plate system |
US6984235B2 (en) | 1993-01-21 | 2006-01-10 | Acumed Llc | System for fusing joints |
US7077844B2 (en) | 1997-02-11 | 2006-07-18 | Sdgi Holdings, Inc. | Segmentable skeletal plating system |
US8974506B2 (en) | 2009-11-09 | 2015-03-10 | Spinewelding Ag | Medical device, apparatus, and surgical method |
US9161793B2 (en) | 1993-01-21 | 2015-10-20 | Acumed Llc | Axial tension screw |
US10335216B2 (en) | 2011-07-15 | 2019-07-02 | Globus Medical, Inc. | Screw implants for bone fusion |
US10925653B2 (en) | 2011-07-15 | 2021-02-23 | Globus Medical, Inc. | Screw implants for bone fusion |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1562811A (en) * | 1967-09-27 | 1969-04-11 | ||
AU5965869A (en) * | 1968-09-09 | 1971-02-25 | Illinois Toolworks, Inc | Screw-type fasteners |
CH546351A (en) * | 1971-11-22 | 1974-02-28 | Litton Export Trade Corp | SELF-LOCKING SCREW. |
AU1344176A (en) * | 1975-04-28 | 1977-11-03 | Downs Surgical Limited | Surgical screw implant |
AU3329878A (en) * | 1977-02-24 | 1979-08-23 | Interfix Ltd. | Bone screw |
EP0129404A1 (en) * | 1983-06-15 | 1984-12-27 | ITW Limited | Fixings including screws and clamp plates |
EP0144503B1 (en) * | 1983-09-02 | 1986-11-26 | Friedr. Boesner GmbH | Connecting element for two machine parts or structural parts,for example extensible fit screw |
AU1280088A (en) * | 1987-03-13 | 1988-09-15 | Societe De Fabrication De Materiel Orthopedique - Sofamor | Vertebral screw for an osteosynthesis device in particular of the lumbar and dorsal rachis |
-
1989
- 1989-09-11 WO PCT/AU1989/000386 patent/WO1990002526A1/en unknown
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1562811A (en) * | 1967-09-27 | 1969-04-11 | ||
AU5965869A (en) * | 1968-09-09 | 1971-02-25 | Illinois Toolworks, Inc | Screw-type fasteners |
CH546351A (en) * | 1971-11-22 | 1974-02-28 | Litton Export Trade Corp | SELF-LOCKING SCREW. |
AU1344176A (en) * | 1975-04-28 | 1977-11-03 | Downs Surgical Limited | Surgical screw implant |
AU3329878A (en) * | 1977-02-24 | 1979-08-23 | Interfix Ltd. | Bone screw |
EP0129404A1 (en) * | 1983-06-15 | 1984-12-27 | ITW Limited | Fixings including screws and clamp plates |
EP0144503B1 (en) * | 1983-09-02 | 1986-11-26 | Friedr. Boesner GmbH | Connecting element for two machine parts or structural parts,for example extensible fit screw |
AU1280088A (en) * | 1987-03-13 | 1988-09-15 | Societe De Fabrication De Materiel Orthopedique - Sofamor | Vertebral screw for an osteosynthesis device in particular of the lumbar and dorsal rachis |
Cited By (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5147363A (en) * | 1989-12-21 | 1992-09-15 | Haerle Anton | Screw for use in osteosynthesis |
EP0472017A1 (en) * | 1990-08-24 | 1992-02-26 | Anton Prof. Dr. Härle | Cylindrical bodies with external thread |
EP0491211A1 (en) * | 1990-12-19 | 1992-06-24 | Synthes AG, Chur | Bone screw |
US9161793B2 (en) | 1993-01-21 | 2015-10-20 | Acumed Llc | Axial tension screw |
US5964768A (en) * | 1993-01-21 | 1999-10-12 | Acumed, Inc. | Tapered bone screw with continuously varying pitch |
US6984235B2 (en) | 1993-01-21 | 2006-01-10 | Acumed Llc | System for fusing joints |
US6299615B1 (en) | 1993-01-21 | 2001-10-09 | Acumed, Inc. | System for fusing joints |
FR2739151A1 (en) * | 1995-09-22 | 1997-03-28 | Numedic | Fixing screw for bone implants |
US6936050B2 (en) | 1997-02-11 | 2005-08-30 | Gary K. Michelson | Multilock anterior cervical plating system |
US7137984B2 (en) | 1997-02-11 | 2006-11-21 | Warsaw Orthopedic, Inc. | Single-lock anterior cervical plate and method |
EP1393689A2 (en) * | 1997-02-11 | 2004-03-03 | MICHELSON, Gary Karlin | Anterior cervical plating system and bone screw |
EP1393689A3 (en) * | 1997-02-11 | 2004-03-17 | MICHELSON, Gary Karlin | Anterior cervical plating system and bone screw |
US8480717B2 (en) | 1997-02-11 | 2013-07-09 | Warsaw Orthopedic, Inc. | Orthopedic implant with locking element |
US8262708B2 (en) | 1997-02-11 | 2012-09-11 | Warsaw Orthopedic, Inc. | Single-lock plating system |
US8048075B2 (en) | 1997-02-11 | 2011-11-01 | Warsaw Orthopedic, Inc. | Orthopedic implant with locking element |
US8641743B2 (en) | 1997-02-11 | 2014-02-04 | Warsaw Orthopedic, Inc. | Orthopedic implant with locking element |
US6916320B2 (en) | 1997-02-11 | 2005-07-12 | Gary K. Michelson | Anterior cervical plate system |
US6926718B1 (en) | 1997-02-11 | 2005-08-09 | Gary K. Michelson | Multilock anterior cervical plating system |
US7077844B2 (en) | 1997-02-11 | 2006-07-18 | Sdgi Holdings, Inc. | Segmentable skeletal plating system |
US6936051B2 (en) | 1997-02-11 | 2005-08-30 | Gary K. Michelson | Multilock anterior cervical plating system |
US6969390B2 (en) | 1997-02-11 | 2005-11-29 | Michelson Gary K | Anterior cervical plating system and bone screw |
US7074221B2 (en) | 1997-02-11 | 2006-07-11 | Sdgi Holdings, Inc. | Anterior cervical plate system |
WO2000032125A1 (en) * | 1998-11-26 | 2000-06-08 | Synthes Ag Chur | Screw |
US6030162A (en) * | 1998-12-18 | 2000-02-29 | Acumed, Inc. | Axial tension screw |
US6989014B2 (en) | 2000-04-04 | 2006-01-24 | Ethicon, Inc. | Orthopedic screw and method |
US7578836B2 (en) | 2000-04-04 | 2009-08-25 | Depuy Mitek | Orthopedic screw and method |
US6527777B2 (en) | 2000-04-04 | 2003-03-04 | Ethicon, Inc. | Device for repairing a soft-tissue tear and method |
US6468277B1 (en) | 2000-04-04 | 2002-10-22 | Ethicon, Inc. | Orthopedic screw and method |
US6875215B2 (en) * | 2002-02-15 | 2005-04-05 | John Stanley Taras | Distraction pin for fracture fixation |
WO2004086991A1 (en) | 2003-04-03 | 2004-10-14 | Stratec Medical Ag | Bone screw |
GB2406056B (en) * | 2003-09-17 | 2007-07-11 | Corin Ltd | Prosthetic cup |
US7641656B2 (en) | 2003-09-17 | 2010-01-05 | Corin Limited | Prosthetic cup |
GB2406056A (en) * | 2003-09-17 | 2005-03-23 | Corin Ltd | Bone tapping kit, fixation member and prosthetic cup |
WO2005058175A1 (en) | 2003-12-19 | 2005-06-30 | Depuy International Limited | A bone screw |
EP2910207A1 (en) | 2009-11-09 | 2015-08-26 | Spinewelding AG | Medical device, apparatus |
EP2898843A2 (en) | 2009-11-09 | 2015-07-29 | Spinewelding AG | Medical device, apparatus, and surgical method |
US8974506B2 (en) | 2009-11-09 | 2015-03-10 | Spinewelding Ag | Medical device, apparatus, and surgical method |
US9566099B2 (en) | 2009-11-09 | 2017-02-14 | Spinewelding Ag | Medical device, apparatus, and surgical method |
EP3141202A1 (en) | 2009-11-09 | 2017-03-15 | Spinewelding AG | Medical device, apparatus |
US10342587B2 (en) | 2009-11-09 | 2019-07-09 | Spinewelding Ag | Medical device, apparatus, and surgical method |
US11179183B2 (en) | 2009-11-09 | 2021-11-23 | Spinewelding Ag | Medical device, apparatus, and surgical method |
US11832861B2 (en) | 2009-11-09 | 2023-12-05 | Spinewelding Ag | Medical device, apparatus, and surgical method |
US10335216B2 (en) | 2011-07-15 | 2019-07-02 | Globus Medical, Inc. | Screw implants for bone fusion |
US10925653B2 (en) | 2011-07-15 | 2021-02-23 | Globus Medical, Inc. | Screw implants for bone fusion |
US11723703B2 (en) | 2011-07-15 | 2023-08-15 | Globus Medical, Inc. | Screw implants for bone fusion |
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