USB313531I5 - - Google Patents

Info

Publication number
USB313531I5
USB313531I5 US31353172A USB313531I5 US B313531 I5 USB313531 I5 US B313531I5 US 31353172 A US31353172 A US 31353172A US B313531 I5 USB313531 I5 US B313531I5
Authority
US
United States
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
Inventor
H Ott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Priority to US313531A priority Critical patent/US3925548A/en
Publication of USB313531I5 publication Critical patent/USB313531I5/en
Application granted granted Critical
Publication of US3925548A publication Critical patent/US3925548A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
US313531A 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents Expired - Lifetime US3925548A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US313531A US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation
US313531A US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Publications (2)

Publication Number Publication Date
USB313531I5 true USB313531I5 (en) 1975-01-28
US3925548A US3925548A (en) 1975-12-09

Family

ID=25103642

Family Applications (2)

Application Number Title Priority Date Filing Date
US00775201A Expired - Lifetime US3723432A (en) 1967-10-04 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation
US313531A Expired - Lifetime US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US00775201A Expired - Lifetime US3723432A (en) 1967-10-04 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Country Status (19)

Country Link
US (2) US3723432A (en)
AT (4) AT310176B (en)
BE (1) BE741529A (en)
BG (10) BG16042A3 (en)
BR (1) BR6914095D0 (en)
CH (1) CH521972A (en)
DE (1) DE1956384C3 (en)
DK (1) DK129347B (en)
ES (1) ES373377A1 (en)
FR (1) FR2024830B1 (en)
GB (1) GB1282612A (en)
IE (1) IE33933B1 (en)
IL (1) IL33348A (en)
NL (1) NL6916514A (en)
NO (1) NO124032B (en)
OA (1) OA03829A (en)
PL (1) PL72695B1 (en)
SE (2) SE376917B (en)
ZA (1) ZA697910B (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (en) * 1971-07-08 1973-01-08 Sandoz Sa NEW DERIVATIVES OF QUINAZOLINE, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (en) * 1979-07-05 1984-09-28 Sandoz Ag METHOD FOR PRODUCING 4-PHENYL-2 (1H) -QUINAZOLINONES.
FR2676042B1 (en) * 1991-05-02 1993-07-23 Commissariat Energie Atomique PROCESS FOR THE PREPARATION OF AN ALKALI METAL BOROHYDRIDE SUCH AS LITHIUM BOROHYDRIDE.
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
AR038658A1 (en) 2001-06-15 2005-01-26 Novartis Ag DERIVATIVES OF 4-ARIL-2 (1H) QUINAZOLINONA AND 4-ARIL-QUINAZOLINA 2-SUBSTITUTES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND THE USE OF SUCH DERIVATIVES FOR THE PREPARATION OF A MEDICINAL PRODUCT
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
AU2003213092A1 (en) * 2002-02-15 2003-09-09 Smithkline Beecham Corporation Syntheses of quinazolinones
US7214800B2 (en) * 2002-05-09 2007-05-08 Cytokinetics, Inc. Compounds, compositions, and methods
RU2004135554A (en) * 2002-05-09 2006-01-20 Цитокинетикс, Инк. (Us) Pyrimidinones, compositions based on them and methods for their use
AU2003265242A1 (en) * 2002-05-23 2003-12-22 Cytokinetics, Inc. Compounds, compositions, and methods
EP1556357A4 (en) * 2002-06-14 2006-09-13 Cytokinetics Inc Compounds, compositions, and methods
WO2004009036A2 (en) * 2002-07-23 2004-01-29 Cytokinetics, Inc. Compounds compositions and methods
JP2005536553A (en) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド Compounds, compositions and methods
AU2003277079A1 (en) * 2002-09-30 2004-05-04 Cytokinetics, Inc. Compounds, compositions, and methods
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
WO2005041888A2 (en) * 2003-11-03 2005-05-12 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions and methods
EP1680420A4 (en) * 2003-11-07 2008-09-24 Cytokinetics Inc Compounds, compositions, and methods
JP2007513154A (en) * 2003-12-08 2007-05-24 サイトキネティクス・インコーポレーテッド Compounds, compositions and methods
AU2008268613A1 (en) * 2007-06-22 2008-12-31 Arqule, Inc. Quinazolinone compounds and methods of use thereof
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) * 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
KR20130010122A (en) 2010-03-26 2013-01-25 갈데르마 리써어치 앤드 디벨로프먼트 Improved methods and compositions for safe and effective treatment of telangiectasia
CA2792646C (en) 2010-03-26 2018-11-20 Galderma Research & Development Improved uses and compositions for safe and effective treatment of erythema
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
US20130261126A1 (en) 2010-10-21 2013-10-03 Galderma S.A. Brimonidiine gel compositions and methods of use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
BG16036A3 (en) 1972-05-20
FR2024830B1 (en) 1973-07-13
BG16042A3 (en) 1972-05-20
NO124032B (en) 1972-02-21
BR6914095D0 (en) 1973-02-13
DE1956384A1 (en) 1970-06-11
AT310176B (en) 1973-09-25
US3925548A (en) 1975-12-09
DK129347B (en) 1974-09-30
ZA697910B (en) 1971-07-28
ES373377A1 (en) 1972-05-16
NL6916514A (en) 1970-05-14
BG16043A3 (en) 1972-05-20
DE1956384B2 (en) 1980-02-07
BG16038A3 (en) 1972-05-20
BG16037A3 (en) 1972-05-20
CH521972A (en) 1972-04-30
FR2024830A1 (en) 1970-09-04
BE741529A (en) 1970-05-11
GB1282612A (en) 1972-07-19
IE33933L (en) 1970-05-12
BG16041A3 (en) 1972-05-20
AT319949B (en) 1975-01-10
IL33348A (en) 1973-04-30
BG16039A3 (en) 1972-05-20
US3723432A (en) 1973-03-27
SE376917B (en) 1975-06-16
SU366612A3 (en) 1973-01-16
PL72695B1 (en) 1974-08-30
DK129347C (en) 1975-02-17
IL33348A0 (en) 1970-01-29
BG16188A3 (en) 1972-07-20
AT310169B (en) 1973-09-25
AT319950B (en) 1975-01-10
OA03829A (en) 1971-12-24
IE33933B1 (en) 1974-12-11
SE374920B (en) 1975-03-24
DE1956384C3 (en) 1980-10-09
BG16040A3 (en) 1972-05-20
BG15573A3 (en) 1976-06-26

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