US4153186A - Valve and medicant dispensing syringe - Google Patents

Valve and medicant dispensing syringe Download PDF

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Publication number
US4153186A
US4153186A US05/817,142 US81714277A US4153186A US 4153186 A US4153186 A US 4153186A US 81714277 A US81714277 A US 81714277A US 4153186 A US4153186 A US 4153186A
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Prior art keywords
dispensing
syringe
seal
cup
outer sleeve
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US05/817,142
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Norman H. Nye
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/14—Check valves with flexible valve members
    • F16K15/1402—Check valves with flexible valve members having an integral flexible member cooperating with a plurality of seating surfaces
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/14—Check valves with flexible valve members
    • F16K15/144—Check valves with flexible valve members the closure elements being fixed along all or a part of their periphery
    • F16K15/145—Check valves with flexible valve members the closure elements being fixed along all or a part of their periphery the closure elements being shaped as a solids of revolution, e.g. cylindrical or conical
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/14—Check valves with flexible valve members
    • F16K15/144—Check valves with flexible valve members the closure elements being fixed along all or a part of their periphery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7837—Direct response valves [i.e., check valve type]
    • Y10T137/7879—Resilient material valve
    • Y10T137/7888—With valve member flexing about securement
    • Y10T137/7889—Sleeve

Definitions

  • the present invention relates to an improved, relatively inexpensive positive acting device for processing materials, such as medicines, in a sanitary manner, and for dispensing measured quantities thereof into receiving containers or cups to fill a desired quantity of these containers with unit doses of the medicines.
  • the dispensing syringe of the invention is relatively inexpensive and uncomplicated, whereby it can be discarded after one use thereof in filling, for example, from between about 50 to 200 or 300 of the carrier containers.
  • U.S. Pat. No. 2,894,665 One prior type of a mechanism for dispensing a liquid is shown in U.S. Pat. No. 2,894,665, and it has a one-way valve means at a lower end of the measuring container and a float body that aids in forming a seal with the piston for expulsion of the liquid being processed.
  • the apparatus of the present invention is much more positive in action and less complex in design than such patent.
  • Another prior dispenser for viscous liquids is shown in U.S. Pat. No. 3,231,149, wherein an axially movable plunger is carried in a cylinder and a fixed closure valve and dispensing means is provided at the lower end of the container. But this is a particular structure differing materially from the compact uncomplicated apparatus of the present invention.
  • U.S. Pat. No. 2,894,665 also shows a typical apparatus with which the dispensing syringe of the invention can be used for being driven through a controlled cycle for efficiently measuring and dispensing a desired quantity of a liquid material.
  • the general object of the present invention is to provide an improved valve and dispensing unit, especially adapted for processing medicines and efficiently dispensing measured quantities thereof.
  • Another objects of the invention are to provide a one-way seal and valve means for use in a measuring and dispensing syringe or the like; and to secure a seal in a syringe by an edge bead on a resilient diaphragm seal.
  • Yet a further object of the invention is to provide two substantially identical valve and diaphragm seal members used in spaced axial relationship in a dispensing syringe for providing a low cost, reliable dispensing apparatus.
  • FIG. 1 is a vertical section through a dispensing syringe, embodying the invention, having a supply tube connected thereto;
  • FIG. 2 is a horizontal section taken on line 2--2 of FIG. 1.
  • the dispensing syringe is made from a pair of plastic inner and outer sleeves that are telescopically engaged and have open receiving ends and an insert cup extending across and positioned in the outer sleeve adjacent its dispensing end, the outer sleeve having a dispensing end and the insert cup having a dispensing base or end and with the external contours of such dispensing ends being of the same general shapes and sizes and including an annular recess extending around the periphery of the end, and a pair of sealing diaphragms or means resiliently engaging the outer dispensing end of the inner sleeve and the dispensing end of the insert cup, the seal means having an edge rib securely received in said annular recess, such seal diaphragms each having a discharge hole on a center axis thereof and with the dispensing ends of said inner sleeve and said insert cup having openings therein offset from the center axis of the syringe where
  • the syringe of the invention is adapted to be used in apparatus as shown in U.S. Pat. No. 2,894,665, but other unit dosage liquid and solid packaging machines have also been provided and are currently made in commercial models for rapidly and accurately loading desired quantities of a medicant into unit containers. This action can be provided by the dispensing syringe of the invention and have uniform quantities of materials passed through the apparatus in a sanitary manner.
  • This syringe 10 includes an outer sleeve or cylinder 12 and an inner sleeve or cylinder 14 telescopically engaged with and received in the outer cylinder 12.
  • the inner sleeve preferably is provided with a plurality of axially directed circumferentially spaced ribs 16 provided at uniformly spaced portions around the periphery of the inner sleeve to guide the inner sleeve in the outer sleeve for axial reciprocation on the center axis of the syringe. Also, these ribs 16 aid in providing a radial space for attaching seal means to the inner sleeve 14 as hereinafter described.
  • the inner sleeve 14 has a normally closed dispensing end 18, and an insert cup 20 is also present and is received in the lower portion of the outer sleeve 12.
  • This insert cup 20 also has a dispensing end or base portion 22 that is normally closed or sealed.
  • a pair of correspondingly shaped and sized resilient seal means, webs, or diaphragms 24 and 26 are provided one in engagement with the dispensing end 18 of the inner sleeve and the other in resilient engagement with the sealing end 22 or base of the insert cup 20.
  • These seal diaphragms are provided with dispensing holes or openings 28 positioned on the axis of the syringe, while other dispensing openings 30 and 32 are formed in the dispensing end 18 and the base or end 22 of the cup and with such openings 30 and 32 being in offset axial relation to the openings 28 in the seal diaphragms.
  • a plurality of these openings 30 and 32 can be provided in radially spaced relation to the openings 28.
  • These seal diaphragms are tightly and resiliently positioned in engagement with the outer surfaces of the dispensing ends or bases of the members to which they are attached, and note that the lower end of the inner sleeve 14 has an annular recess 34 formed therein by adjacent substantially radially extending flanges 36 and 38.
  • edge ribs or portions 40 on these seal diaphragms 24 and 26 are snugly received in and are resiliently retained in engagement with the associated portions of the dispensing syringe by these annular ribs 40 on the diaphragm, and by the shape and size of these seal diaphragms.
  • a recess 42 is formed in the outer periphery of the insert cup 20 by a shoulder 44 and a rib or flange 46 axially spaced therefrom and shorter in radial length than the shoulder 44 to be spaced from the outer sleeve to pass the web of the seal diaphragm between such insert cup and the adjacent surface of the outer cylinder or sleeve 12.
  • outer sleeve 12 has a dispensing nozzle 48 formed at its lower end.
  • a suitable supply tube 50 can be and is attached to the open upper receiving end of the inner sleeve 14 of the syringe.
  • a connector fitting 52 is conventionally secured to the upper end of the inner sleeve 14 and engages the tube 50 to connect it to the syringe.
  • any desired pump device or the like can be operatively connected to the syringe for supplying measured quantities of materials, usually liquid, to the syringe to be forced therethrough after the syringe has been filled with the material to be dispensed.
  • the outer cylinder or sleeve 12 can be fixed to a suitable support and then the inner sleeve could be moved through operative cycles for dispensing measured quantities of material.
  • valve or syringe of the invention has good operative properties, it is inexpensive, and it will dispense controlled quantities, as desired. Thus the objects of the specification have been met.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A dispensing syringe comprising telescopically engaged inner and outer sleeves or cylinders having corresponding dispensing ends and open receiving ends, an insert cup extends across and is positioned in the outer cylinder at its dispensing end, and a pair of identical resilient seal diaphragms engaging the outer surfaces of the dispensing end of the inner cylinder and of the insert cup for flow of material through the syringe in one direction. The seal diaphragms are of the same constructions for resilient engagement with the ends of the inner sleeve and the insert cup.

Description

BACKGROUND OF INVENTION
In these days of high medical expenses and increasing costs for medicines, it is important that medicines be provided in unit forms available for convenient handling at the hospital and ease of dispensing medicines in these unit containers. Thus, efforts have been made heretofore to provide apparatus which has been proposed for filling cups or other containers with measured quantities of medicines to provide for convenient, inexpensive dispensing and handling of the medicines.
The present invention relates to an improved, relatively inexpensive positive acting device for processing materials, such as medicines, in a sanitary manner, and for dispensing measured quantities thereof into receiving containers or cups to fill a desired quantity of these containers with unit doses of the medicines. The dispensing syringe of the invention is relatively inexpensive and uncomplicated, whereby it can be discarded after one use thereof in filling, for example, from between about 50 to 200 or 300 of the carrier containers.
One prior type of a mechanism for dispensing a liquid is shown in U.S. Pat. No. 2,894,665, and it has a one-way valve means at a lower end of the measuring container and a float body that aids in forming a seal with the piston for expulsion of the liquid being processed. The apparatus of the present invention is much more positive in action and less complex in design than such patent. Another prior dispenser for viscous liquids is shown in U.S. Pat. No. 3,231,149, wherein an axially movable plunger is carried in a cylinder and a fixed closure valve and dispensing means is provided at the lower end of the container. But this is a particular structure differing materially from the compact uncomplicated apparatus of the present invention.
U.S. Pat. No. 2,894,665 also shows a typical apparatus with which the dispensing syringe of the invention can be used for being driven through a controlled cycle for efficiently measuring and dispensing a desired quantity of a liquid material.
The general object of the present invention is to provide an improved valve and dispensing unit, especially adapted for processing medicines and efficiently dispensing measured quantities thereof.
Other objects of the invention are to provide a one-way seal and valve means for use in a measuring and dispensing syringe or the like; and to secure a seal in a syringe by an edge bead on a resilient diaphragm seal.
Yet a further object of the invention is to provide two substantially identical valve and diaphragm seal members used in spaced axial relationship in a dispensing syringe for providing a low cost, reliable dispensing apparatus.
The foregoing and other objects and advantages of the invention will be made more apparent as the specification proceeds.
In the accompanying drawings,
FIG. 1 is a vertical section through a dispensing syringe, embodying the invention, having a supply tube connected thereto; and
FIG. 2 is a horizontal section taken on line 2--2 of FIG. 1.
SUBJECT MATTER OF INVENTION
The dispensing syringe, as one embodiment of the invention, is made from a pair of plastic inner and outer sleeves that are telescopically engaged and have open receiving ends and an insert cup extending across and positioned in the outer sleeve adjacent its dispensing end, the outer sleeve having a dispensing end and the insert cup having a dispensing base or end and with the external contours of such dispensing ends being of the same general shapes and sizes and including an annular recess extending around the periphery of the end, and a pair of sealing diaphragms or means resiliently engaging the outer dispensing end of the inner sleeve and the dispensing end of the insert cup, the seal means having an edge rib securely received in said annular recess, such seal diaphragms each having a discharge hole on a center axis thereof and with the dispensing ends of said inner sleeve and said insert cup having openings therein offset from the center axis of the syringe whereby the resilient diaphragms normally retain the dispensing ends of the inner sleeve and of the insert cup closed but with dispensing pressure opening the diaphragm means for flow of material to be dispensed therethrough.
The syringe of the invention, as previously indicated, is adapted to be used in apparatus as shown in U.S. Pat. No. 2,894,665, but other unit dosage liquid and solid packaging machines have also been provided and are currently made in commercial models for rapidly and accurately loading desired quantities of a medicant into unit containers. This action can be provided by the dispensing syringe of the invention and have uniform quantities of materials passed through the apparatus in a sanitary manner.
Reference now is particularly directed to the structure shown in the drawings and wherein a dispensing syringe 10 is provided. This syringe 10 includes an outer sleeve or cylinder 12 and an inner sleeve or cylinder 14 telescopically engaged with and received in the outer cylinder 12. The inner sleeve preferably is provided with a plurality of axially directed circumferentially spaced ribs 16 provided at uniformly spaced portions around the periphery of the inner sleeve to guide the inner sleeve in the outer sleeve for axial reciprocation on the center axis of the syringe. Also, these ribs 16 aid in providing a radial space for attaching seal means to the inner sleeve 14 as hereinafter described.
The inner sleeve 14 has a normally closed dispensing end 18, and an insert cup 20 is also present and is received in the lower portion of the outer sleeve 12. This insert cup 20 also has a dispensing end or base portion 22 that is normally closed or sealed.
To aid in dispensing action and control of material being moved through the syringe of the invention, a pair of correspondingly shaped and sized resilient seal means, webs, or diaphragms 24 and 26 are provided one in engagement with the dispensing end 18 of the inner sleeve and the other in resilient engagement with the sealing end 22 or base of the insert cup 20. These seal diaphragms are provided with dispensing holes or openings 28 positioned on the axis of the syringe, while other dispensing openings 30 and 32 are formed in the dispensing end 18 and the base or end 22 of the cup and with such openings 30 and 32 being in offset axial relation to the openings 28 in the seal diaphragms. A plurality of these openings 30 and 32 can be provided in radially spaced relation to the openings 28. These seal diaphragms are tightly and resiliently positioned in engagement with the outer surfaces of the dispensing ends or bases of the members to which they are attached, and note that the lower end of the inner sleeve 14 has an annular recess 34 formed therein by adjacent substantially radially extending flanges 36 and 38. Thus, edge ribs or portions 40 on these seal diaphragms 24 and 26 are snugly received in and are resiliently retained in engagement with the associated portions of the dispensing syringe by these annular ribs 40 on the diaphragm, and by the shape and size of these seal diaphragms. A recess 42, corresponding to the recess 34, is formed in the outer periphery of the insert cup 20 by a shoulder 44 and a rib or flange 46 axially spaced therefrom and shorter in radial length than the shoulder 44 to be spaced from the outer sleeve to pass the web of the seal diaphragm between such insert cup and the adjacent surface of the outer cylinder or sleeve 12.
It will be noted that the outer sleeve 12 has a dispensing nozzle 48 formed at its lower end.
The drawing shows that a suitable supply tube 50 can be and is attached to the open upper receiving end of the inner sleeve 14 of the syringe. Usually some type of a connector fitting 52 is conventionally secured to the upper end of the inner sleeve 14 and engages the tube 50 to connect it to the syringe. Hence, any desired pump device or the like can be operatively connected to the syringe for supplying measured quantities of materials, usually liquid, to the syringe to be forced therethrough after the syringe has been filled with the material to be dispensed. Or, as shown in U.S. Pat. No. 2,894,665, the outer cylinder or sleeve 12 can be fixed to a suitable support and then the inner sleeve could be moved through operative cycles for dispensing measured quantities of material.
The valve or syringe of the invention has good operative properties, it is inexpensive, and it will dispense controlled quantities, as desired. Thus the objects of the specification have been met.
While one complete embodiment of the invention has been disclosed herein, it will be appreciated that modification of this particular embodiment of the invention may be resorted to without departing from the scope of the invention.

Claims (4)

What is claimed is:
1. A dispensing syringe having an outlet and comprising an inner and an outer sleeve that are telescopically engaged and have corresponding dispensing ends and open receiving ends,
a separate seal cup in and extending across the internal diameter of said outer sleeve and positioned in said outer sleeve adjacent its dispensing end, said seal cup having a dispensing end,
a pair of resilient seal means individually engaging the outer surfaces of said dispensing end of said inner sleeve and of said seal cup for flow of material only towards the syringe outlet, said dispensing ends and seal means having openings therein offset in relation to each other, and the outer surfaces of the dispensing end of said seal cup and of said inner sleeve being of the same contour, said seal means being of the same size and configuration and tightly engaging said dispensing ends, a lower peripheral portion of said seal cup being spaced from said outer sleeve to receive an edge portion of a seal means.
2. A dispensing syringe comprising telescopically engaged inner and outer sleeves having corresponding dispensing ends and open receiving ends, said outer sleeve having a nozzle defining an outlet at its dispensing end,
an insert cup positioned in said outer sleeve and extending across the internal diameter of said outer sleeve adjacent its dispensing end, said insert cup having a dispensing end and
a pair of corresponding flexible seal means, of the same size and shape, tightly engaging the outer surfaces of said dispensing end of said inner sleeve and of said insert cup for flow of material only towards the syringe outlet, said dispensing ends having openings therein offset from the center axis of said sleeves, said seal means having an opening therein on the center axis of the syringe and closing said openings in said dispensing ends of said insert cup and said inner sleeve normally, but opening for flow of material towards said nozzle.
3. A dispensing syringe as in claim 2, where the outer surfaces of the dispensing end of said insert cup and of said inner sleeve are of the same contour and include an annular recess on side areas thereof, and said seal means each has an annular rib seated in its individual said recess to position said seal means and each has a seal web tightly extending over the outer surfaces of one of said dispensing ends, both of said annular ribs on said seal means being retained in position by said outer sleeve.
4. A dispensing syringe as in claim 2, where said outer sleeve has a radially inwardly extending thickened wall portion at the area thereof receiving said insert cup to facilitate positioning said insert cup and the said seal means thereon in said outer sleeve.
US05/817,142 1977-07-20 1977-07-20 Valve and medicant dispensing syringe Expired - Lifetime US4153186A (en)

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452379A (en) * 1982-07-09 1984-06-05 Bundschuh Robert L Pump dispenser with one-piece stretchable biasing member and valve
US4479593A (en) * 1982-07-09 1984-10-30 Bundschuh Robert L Pump dispenser with adjustable nozzle
US4632281A (en) * 1984-03-29 1986-12-30 Johnstone Pump Company Magnadrum pump assembly
US4646781A (en) * 1985-05-07 1987-03-03 Pacesetter Infusion, Ltd. Diaphragm valve for medication infusion pump
EP0230232A2 (en) * 1986-01-21 1987-07-29 Abbott Laboratories Intravenous administration set incorporating secondary fluid delivery
US5265621A (en) * 1992-03-31 1993-11-30 Simpson Shawn L Apparatus for sampling blood
US5277342A (en) * 1992-12-11 1994-01-11 Loctite Corporation Sealless dispensing apparatus
US6644309B2 (en) * 2001-01-12 2003-11-11 Becton, Dickinson And Company Medicament respiratory delivery device and method
WO2004074341A1 (en) 2003-02-20 2004-09-02 Invista Technologies S.À.R.L. Articles comprising aqueous dispersions of polyureaurethanes
US20050187532A1 (en) * 2004-02-24 2005-08-25 Medex, Inc. Diaphragm-based reservoir for a closed blood sampling system
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US20070225640A1 (en) * 2004-12-30 2007-09-27 Chang Byeong S Container closure delivery system
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US20120323173A1 (en) * 2011-04-18 2012-12-20 Thorne Consulting And Intellectual Property, Llc Medical syringe filling and valving
US8425453B2 (en) 2004-12-30 2013-04-23 Integrity Bio, Inc. Compact medication reconstitution device and method
US20150065991A1 (en) * 2012-04-09 2015-03-05 Becton, Dickinson And Company Vial dosing systems and methods
US9850058B2 (en) 2015-09-11 2017-12-26 New Product Development Concepts Llc Telescoping syringe with one-way valve
US20180086544A1 (en) * 2015-09-11 2018-03-29 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve
US10201692B2 (en) 2014-09-09 2019-02-12 Byeong Seon Chang Solution delivery device and method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1367008A (en) * 1917-04-09 1921-02-01 Alfred N Bessese Syringe
US1589882A (en) * 1925-02-19 1926-06-22 George N Hein Positive blood-letting hypodermic syringe
US3342208A (en) * 1963-10-03 1967-09-19 Adam P G Steffes Resilient material valve
DE2029179A1 (en) * 1969-06-16 1972-04-20 Cooper, McDougall & Robertson Ltd., Berkhamsted, Hertfordshire (Großbritannien) Injection device
US3678931A (en) * 1970-06-09 1972-07-25 Milton J Cohen Syringe
US3685514A (en) * 1969-09-23 1972-08-22 Paul E Cheney Two compartment syringe

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1367008A (en) * 1917-04-09 1921-02-01 Alfred N Bessese Syringe
US1589882A (en) * 1925-02-19 1926-06-22 George N Hein Positive blood-letting hypodermic syringe
US3342208A (en) * 1963-10-03 1967-09-19 Adam P G Steffes Resilient material valve
DE2029179A1 (en) * 1969-06-16 1972-04-20 Cooper, McDougall & Robertson Ltd., Berkhamsted, Hertfordshire (Großbritannien) Injection device
US3685514A (en) * 1969-09-23 1972-08-22 Paul E Cheney Two compartment syringe
US3678931A (en) * 1970-06-09 1972-07-25 Milton J Cohen Syringe

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452379A (en) * 1982-07-09 1984-06-05 Bundschuh Robert L Pump dispenser with one-piece stretchable biasing member and valve
US4479593A (en) * 1982-07-09 1984-10-30 Bundschuh Robert L Pump dispenser with adjustable nozzle
US4632281A (en) * 1984-03-29 1986-12-30 Johnstone Pump Company Magnadrum pump assembly
US4646781A (en) * 1985-05-07 1987-03-03 Pacesetter Infusion, Ltd. Diaphragm valve for medication infusion pump
EP0230232A2 (en) * 1986-01-21 1987-07-29 Abbott Laboratories Intravenous administration set incorporating secondary fluid delivery
US4685910A (en) * 1986-01-21 1987-08-11 Abbott Laboratories Apparatus and method for delivering secondary fluids to a patient using an intravenous administration set feeding a primary fluid
EP0230232A3 (en) * 1986-01-21 1988-01-13 Abbott Laboratories Intravenous administration set incorporating secondary fluid delivery
US5265621A (en) * 1992-03-31 1993-11-30 Simpson Shawn L Apparatus for sampling blood
US5277342A (en) * 1992-12-11 1994-01-11 Loctite Corporation Sealless dispensing apparatus
US6644309B2 (en) * 2001-01-12 2003-11-11 Becton, Dickinson And Company Medicament respiratory delivery device and method
WO2004074341A1 (en) 2003-02-20 2004-09-02 Invista Technologies S.À.R.L. Articles comprising aqueous dispersions of polyureaurethanes
US20050187532A1 (en) * 2004-02-24 2005-08-25 Medex, Inc. Diaphragm-based reservoir for a closed blood sampling system
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US20070225640A1 (en) * 2004-12-30 2007-09-27 Chang Byeong S Container closure delivery system
US7959600B2 (en) 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system
US9174002B2 (en) 2004-12-30 2015-11-03 Byeong S. Chang Method for storing and delivering a drug
US10624815B2 (en) 2004-12-30 2020-04-21 Byeong Seon Chang Compact medication reconstitution device and method
US8425453B2 (en) 2004-12-30 2013-04-23 Integrity Bio, Inc. Compact medication reconstitution device and method
US8579855B2 (en) 2004-12-30 2013-11-12 Byeong S. Chang Method for storing and delivering a drug
US10105285B2 (en) 2004-12-30 2018-10-23 Byeong Seon Chang Compact medication reconstitution device and method
US9463139B2 (en) 2004-12-30 2016-10-11 Byeong Seon Chang Compact medication reconstitution device and method
US20110159779A1 (en) * 2009-12-24 2011-06-30 Willy Chen Water shooting toy with high capacity
US8992505B2 (en) * 2011-04-18 2015-03-31 Thorne Consulting & Intellectual Property, LLC Medical syringe filling and valving
US20120323173A1 (en) * 2011-04-18 2012-12-20 Thorne Consulting And Intellectual Property, Llc Medical syringe filling and valving
US20150065991A1 (en) * 2012-04-09 2015-03-05 Becton, Dickinson And Company Vial dosing systems and methods
US10569018B2 (en) * 2012-04-09 2020-02-25 Becton, Dickinson And Company Vial dosing systems and methods
US10201692B2 (en) 2014-09-09 2019-02-12 Byeong Seon Chang Solution delivery device and method
US10894152B2 (en) 2014-09-09 2021-01-19 Byeong Seon Chang Solution delivery device and method
US9850058B2 (en) 2015-09-11 2017-12-26 New Product Development Concepts Llc Telescoping syringe with one-way valve
US20180086544A1 (en) * 2015-09-11 2018-03-29 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve
US10450124B2 (en) * 2015-09-11 2019-10-22 New Product Development Concepts Llc Telescoping syringe with one-way valve

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