US2064815A - Apparatus for filling syringe cartridges and the like - Google Patents
Apparatus for filling syringe cartridges and the like Download PDFInfo
- Publication number
- US2064815A US2064815A US684525A US68452533A US2064815A US 2064815 A US2064815 A US 2064815A US 684525 A US684525 A US 684525A US 68452533 A US68452533 A US 68452533A US 2064815 A US2064815 A US 2064815A
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- United States
- Prior art keywords
- cartridge
- container
- cylinder
- tube
- piston
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
Definitions
- This invention relates to an apparatus for filling syringe cartridges and the like.
- An object of this invention is the provision of a device for economically filling, or refilling, under sterile conditions, tubular containers variously known as syringe cartridges, ampules or carpules, with anesthetic or other solutions or medicaments.
- Another object of this invention is the provision of such a device of a simple and inexpensive construction whereby users of ampules and the like may economically fill or refill their own ampules or cartridges obviating the necessity for the purchase of filled cartridges.
- the use of this invention makes it possible for the user to have a choice of medicaments not commercially available in cartridges.
- a further object is the provision of such a device, utilizing the atmospheric pressure for assisting in the filling operation.
- Figure 1 is a side elevation of a cartridge filling device incorporating my invention.
- Figure 2 is a front elevation of the device shown in Figure 1.
- Figure 3 is a side elevation of a modification of my invention
- Figure 4 is a fragmentary vertical section through a portion of that shown in Figure 3.
- Figure 5 is a section taken on the line V-V of Figure 3.
- the cartridge filling device herein illustrated comprises a supporting frame I pivotally fixed on a base plate l5 and including an integrally formed cartridge guide [6 consisting of two diverging arms l2 also disposed over a portion of the base plate l5 and cooperating therewith to serve as a guide and a seat for the lower end of an ampule or cartridge I! to be filled with liquid.
- an adjustable clamp 6 comprising opposed clamping elements I! and l8 which are adapted to be adjusted toward and from each other by the appropriate rotation of the clamp bolt I9 by the 50 handle 9 permanently fixed on one end thereof.
- an adjustable guide-2l including diverging arms II] which serve as a guide adapted to engage the cartridge ll adjacent the upper end,
- may be adjusted and comprises a slot 23 in the bracket 5 so disposed with relation to the frame I that a screw or bolt 24 passing into the frame I may be forced down upon the bracket 2
- the arms I! and I8 of the bracket 6 embrace the lower end of a pump cylinder 5 which has communication through a tube 21 with a tank 4 adapted to contain the liquid to be transferred to the cartridge 1 I.
- a nozzle or syringe needle 8 15 is removably secured to the lower end of the cylinder 5 by suitable means as indicated at 28.
- Within the upper end of the cylinder 5 is disposed a piston 29 having a relatively tight fit within the cylinder and being secured to the plunger or piston rod 3 which extends from the upper end of the cylinder and is provided with a handle 3
- the tank or liquid container 4 is preferably supported by a bracket 33 secured thereto and to the cylinder 5 adjacent the upper end thereof.
- the extreme upper end of the cylinder 5 is preferably provided with a cap 34 which is threaded thereon and adapted to prevent accidental removal of the piston 29 from the cylinder when the rod 3 is moved upwardly.
- the tank 4 is pref- 35 erably provided with a suitable stopper 2 through which extends a tubular portion 35 of a thistle tube l which is adapted to contain sterile gauze for the purpose of filtering air which may pass from the atmosphere to the tank 4 and by which 1iquid in the tank 4 is caused to flow downwardly into the lower portion of the cylinder 5 when the piston 29 is in its uppermost position as indicated in the drawings.
- two stoppers l3 and M Within the cartridge l I are positioned two stoppers l3 and M, the utility of which will be best understood from the following description of the method of operation:
- the entire device In the process of filling or refilling a cartridge the entire device, together with the cartridges to be used, are properly sterilized. Without a car- 5 tridge in position, the piston 29 is forced downwardly to the lower end of the cylinder 5 for closing the tube 2'! leading to the tank 4 and for expelling air from the cylinder. With the piston in this position, the liquid to be discharged into the cartridge may be put in the tank 4. The thistle tube 1 should then be put into position preferably containing sterilized gauze to filter air which will pass through the same. The cartridge I I is next placed. in position by placing the stopper l3 of the cartridge against the end of the needle, to push the needle through the stop: per.
- the arms In and I2 serve to aid in positioning the cartridge H in alignment with the cylinder with the needle through the stopper l3.
- the piston is next moved to its uppermost position in the cylinder 5, which causes air to be withdrawn from the needle and from the space between the stoppers l3 and, and as the piston 29 reaches its uppermost position,
- the tube 21 leading from the tank 4 is opened permitting liquid to enter the lower end of the cylinder 5 through the tube 21 by means of gravity and assisted by atmospheric pressure by reason of the rarefied condition of gases contained in the lower portion of the cylinder 5.
- the piston 29 is next forced downwardly for forcibly injecting the liquid through the nozzle 8 into the cartridge, at the same time forcing the stopper I4 from the position shown in the drawings to the lower end of the cartridge.
- the cartridge having been filled, is removed from the position shown in the drawings, the needle 8 being withdrawn and the stopper I3 automatically sealing A the opening formed by the needle.
- the cylinder 5 may be graduated to indicate the amount of medicaments being put into the cartridge.
- Themodification of my invention illustrated in Figures 3, 4. and 5, comprises a frame 1 and pump cylinder 5 and associated parts substantially identical to that shown in Figure 1.
- This modification distinguishes from that shown in Figure 1, however, by the substitution of liquid supply means of a diiTerent construction, comprising a socket member 5
- liquid supply means of a diiTerent construction comprising a socket member 5
- the lower end of the socket member is provided with an integrally secured filter tube 58 communicating with the breather tube 56 by a duct 55.
- the filter tube 58 is preferably filled with suitable air filtering material 59, and the lower end of the tube 58 is provided with a cover 6
- is preferably rigidly secured to the pump cylinder 5, by a web portion 63, the lower edge of which is of substantially cylindrical form, defining a feed tube 21', through which liquid may be discharged from the container 54 to the pump cylinder 5, when the lower end of the piston 29 is disposed above the level of the tube 21'.
- the breather tube 56 extend substantially to the bottom of the container 54 in order that liquid from the container 54 will not find its way into the tube 56 and thus downwardly through the filter tube 58.
- the base I 5' for the frame I is secured in position upon a base plate 15 which is in turn permanently secured to a table top 76 by suitable screws or bolts 11.
- the base plate 75 has formed from the body thereof upwardly extending integral lugs 18 disposed at opposite edges of the base l5, and between which the base is adapted to be slid, in order that the entire mechanism may be removed together with its base 85' from its working position for sterilization, by simply drawing the base [5 from between the lugs 18.
- the threaded engagement by which the liquid container is attached to the socket member is by a specially designed thread adapted to fit containers dispensed only by a particular dealer or dealers, in order to encourage the use of medicaments dispensed by such dealer, when employing this refilling mechanism.
- Means for filling syringe cartridges including in combination, a standard, means forming a chamber adapted to be evacuated supported on said standard, said last mentioned means having a needle-like discharge nozzle for entering a cartridge to be filled, means on said standard for supporting a cartridge in position to be filled by said nozzle, a liquid container, means removably supporting said container for gravital discharge of its contents into said chamber, said container supporting means andsaid container having interlocking portions to removably secure said container in operative position, and a breather tube on said container supporting means extending into a supported container to a point above the contents of the container.
- Means for filling a cartridge in combination, a standard, means providing .a chamber adapted to be evacuated supported on said standard, said last means having a needle-like discharge nozzle for entering a cartridge to be filled, a liquid container, means for supporting said container in position for gravital discharge into said chamber, said container supporting meansand container having interlocking portions for removably supporting said container in operative position, a feed tube between said supporting means and chamber, and a breather tube on said supporting means extending into a supported container to a point above the liquid contents of the container.
- Means for filling syringe cartridges including a standard, means providing a chamber adapted to be evacuated mounted on saidstandard, a liquid container, means for removably supporting said container in position for gravital discharge into said chamber, said supporting means and container including interlocking portions to removably secure said container in operative position, a feed tube between said sup porting means and said chamber, a breather tube on said supporting means extending into a supported container to a point above the liquid contents thereof, and means for filtering air admitted to said breather tube.
- Means for filling syringe cartridges comprising in combination, a base and a standard, a piston pump removably supported by said standard above the base, said pump having a needle-like discharge nozzle, means carried by said pump for receiving a supply of liquid filler for the cartridge. a duct between said supply and the interior 01 said pump communicating with the pump interior adjacent the active face of the piston when the same is at the end of its stroke in a.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
Dec. 22, 1936. .1. L. ARMSTRONG 2,064,815
APPARATUS FOR FILLING SYRINGE CARTRIDGES AND THE LIKE Filed Aug. 10, 1935 2 Sheets-Sheet 1 15/ FIG. I
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ATTORNEY APPARATUS FOR FILLING SYRINGE CARTPIDGES AND THE LIKE Filed Aug. 10, 1933 2 Sheets-Sheet 2 W 0 I 9 5 m 9 1 1 5 l J 5 l l. ,IHII rlwr WVMIII I |r IHIIILIII I ll [ll T| I \i W 4. L 8 5 w 1. 5 Q o 6 T HW WWM I u W/ r m NAHUM IMHHI IN /M m ll ll ||l I 1W: MHW r d .YH 1| 1 a mug z wnn hm JMWINQN 5 a lmmmmmmmmummmwmn mmv 5 m 5 6 l I 7 W 2 0 u 1 II E: E:
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Fatentecl Dec. 22, 1936 UNITED STATES PATENT OFFICE APPARATUS FOR FILLING SYRINGE GAR- TRIDGES AND THE LIKE 4 Claims.
This invention relates to an apparatus for filling syringe cartridges and the like.
An object of this invention is the provision of a device for economically filling, or refilling, under sterile conditions, tubular containers variously known as syringe cartridges, ampules or carpules, with anesthetic or other solutions or medicaments.
Another object of this invention is the provision of such a device of a simple and inexpensive construction whereby users of ampules and the like may economically fill or refill their own ampules or cartridges obviating the necessity for the purchase of filled cartridges. The use of this invention makes it possible for the user to have a choice of medicaments not commercially available in cartridges.
A further object is the provision of such a device, utilizing the atmospheric pressure for assisting in the filling operation.
Other objects and advantages of this invention will become apparent to those skilled in the art from the following detailed description with reference to the accompanying drawings.
On the drawings:
Figure 1 is a side elevation of a cartridge filling device incorporating my invention.
Figure 2 is a front elevation of the device shown in Figure 1.
Figure 3 is a side elevation of a modification of my invention;
Figure 4 is a fragmentary vertical section through a portion of that shown in Figure 3; and
Figure 5 is a section taken on the line V-V of Figure 3.
As shown on the drawings:
The cartridge filling device herein illustrated comprises a supporting frame I pivotally fixed on a base plate l5 and including an integrally formed cartridge guide [6 consisting of two diverging arms l2 also disposed over a portion of the base plate l5 and cooperating therewith to serve as a guide and a seat for the lower end of an ampule or cartridge I! to be filled with liquid. On the upper end of the frame 1 is rigidly secured an adjustable clamp 6 comprising opposed clamping elements I! and l8 which are adapted to be adjusted toward and from each other by the appropriate rotation of the clamp bolt I9 by the 50 handle 9 permanently fixed on one end thereof.
Intermediate the ends of the frame 1 is pro- .vided an adjustable guide-2l including diverging arms II] which serve as a guide adapted to engage the cartridge ll adjacent the upper end,
;whereby the cartridge may be held in proper alignment with the filling device by simply pressing the cartridge snugly into the space between the diverging arms on the brackets 16 and 2|. Means whereby the bracket 2| may be adjusted is provided and comprises a slot 23 in the bracket 5 so disposed with relation to the frame I that a screw or bolt 24 passing into the frame I may be forced down upon the bracket 2| by the enlarged head 25 to securely hold the bracket 2| in any adjusted position. 10
The arms I! and I8 of the bracket 6 embrace the lower end of a pump cylinder 5 which has communication through a tube 21 with a tank 4 adapted to contain the liquid to be transferred to the cartridge 1 I. A nozzle or syringe needle 8 15 is removably secured to the lower end of the cylinder 5 by suitable means as indicated at 28. Within the upper end of the cylinder 5 is disposed a piston 29 having a relatively tight fit within the cylinder and being secured to the plunger or piston rod 3 which extends from the upper end of the cylinder and is provided with a handle 3| adapted to transmit reciprocatory motion to piston rod 3 and to the piston 29 for withdrawing air from the cartridge H and from the lower portion of the cylinder and for subsequently forcing liquid from the cylinder into the cartridge.
The tank or liquid container 4 is preferably supported by a bracket 33 secured thereto and to the cylinder 5 adjacent the upper end thereof. The extreme upper end of the cylinder 5 is preferably provided with a cap 34 which is threaded thereon and adapted to prevent accidental removal of the piston 29 from the cylinder when the rod 3 is moved upwardly. The tank 4 is pref- 35 erably provided with a suitable stopper 2 through which extends a tubular portion 35 of a thistle tube l which is adapted to contain sterile gauze for the purpose of filtering air which may pass from the atmosphere to the tank 4 and by which 1iquid in the tank 4 is caused to flow downwardly into the lower portion of the cylinder 5 when the piston 29 is in its uppermost position as indicated in the drawings. Within the cartridge l I are positioned two stoppers l3 and M, the utility of which will be best understood from the following description of the method of operation:
In the process of filling or refilling a cartridge the entire device, together with the cartridges to be used, are properly sterilized. Without a car- 5 tridge in position, the piston 29 is forced downwardly to the lower end of the cylinder 5 for closing the tube 2'! leading to the tank 4 and for expelling air from the cylinder. With the piston in this position, the liquid to be discharged into the cartridge may be put in the tank 4. The thistle tube 1 should then be put into position preferably containing sterilized gauze to filter air which will pass through the same. The cartridge I I is next placed. in position by placing the stopper l3 of the cartridge against the end of the needle, to push the needle through the stop: per. The arms In and I2 serve to aid in positioning the cartridge H in alignment with the cylinder with the needle through the stopper l3. The piston is next moved to its uppermost position in the cylinder 5, which causes air to be withdrawn from the needle and from the space between the stoppers l3 and, and as the piston 29 reaches its uppermost position,
the tube 21 leading from the tank 4 is opened permitting liquid to enter the lower end of the cylinder 5 through the tube 21 by means of gravity and assisted by atmospheric pressure by reason of the rarefied condition of gases contained in the lower portion of the cylinder 5. The piston 29 is next forced downwardly for forcibly injecting the liquid through the nozzle 8 into the cartridge, at the same time forcing the stopper I4 from the position shown in the drawings to the lower end of the cartridge. The cartridge, having been filled, is removed from the position shown in the drawings, the needle 8 being withdrawn and the stopper I3 automatically sealing A the opening formed by the needle.
In this manner it is possible to fill the refill cartridges and give the user a choice of medicaments not commercially available in cartridges.
; If desired, the cylinder 5 may be graduated to indicate the amount of medicaments being put into the cartridge.
Themodification of my invention illustrated in Figures 3, 4. and 5, comprises a frame 1 and pump cylinder 5 and associated parts substantially identical to that shown in Figure 1. This modification distinguishes from that shown in Figure 1, however, by the substitution of liquid supply means of a diiTerent construction, comprising a socket member 5| provided with internal threads as indicated at 52 for receiving the threaded neck 53 of a reservoir 54 which may consist of the original container which is inverted over a breather tube 56, and having its upper end disposed downwardly and in engagement with a gasket 51 seated in the socket member 5 for making a fluid-tight seal within the socket.
The lower end of the socket member is provided with an integrally secured filter tube 58 communicating with the breather tube 56 by a duct 55. The filter tube 58 is preferably filled with suitable air filtering material 59, and the lower end of the tube 58 is provided with a cover 6| having an aperture 62 therethrough to permit the passage of air into the filter tube. The socket member 5| is preferably rigidly secured to the pump cylinder 5, by a web portion 63, the lower edge of which is of substantially cylindrical form, defining a feed tube 21', through which liquid may be discharged from the container 54 to the pump cylinder 5, when the lower end of the piston 29 is disposed above the level of the tube 21'. For the successful operation of this device it is of course necessary that the breather tube 56 extend substantially to the bottom of the container 54 in order that liquid from the container 54 will not find its way into the tube 56 and thus downwardly through the filter tube 58.
, In this modification, the base I 5' for the frame I, is secured in position upon a base plate 15 which is in turn permanently secured to a table top 76 by suitable screws or bolts 11. The base plate 75 has formed from the body thereof upwardly extending integral lugs 18 disposed at opposite edges of the base l5, and between which the base is adapted to be slid, in order that the entire mechanism may be removed together with its base 85' from its working position for sterilization, by simply drawing the base [5 from between the lugs 18.
In the practical application of this device the threaded engagement by which the liquid container is attached to the socket member, is by a specially designed thread adapted to fit containers dispensed only by a particular dealer or dealers, in order to encourage the use of medicaments dispensed by such dealer, when employing this refilling mechanism.
From the foregoing description it will be appreciated by those skilled in the art-that my invention may be modified and changedin many details without departing from the principle thereof, and I desire that the patent to be granted hereon shall not be limited in any manner except as necessitated by the prior art.
I claim as my invention:
1. Means for filling syringe cartridges, including in combination, a standard, means forming a chamber adapted to be evacuated supported on said standard, said last mentioned means having a needle-like discharge nozzle for entering a cartridge to be filled, means on said standard for supporting a cartridge in position to be filled by said nozzle, a liquid container, means removably supporting said container for gravital discharge of its contents into said chamber, said container supporting means andsaid container having interlocking portions to removably secure said container in operative position, and a breather tube on said container supporting means extending into a supported container to a point above the contents of the container.
2. Means for filling a cartridge, in combination, a standard, means providing .a chamber adapted to be evacuated supported on said standard, said last means having a needle-like discharge nozzle for entering a cartridge to be filled, a liquid container, means for supporting said container in position for gravital discharge into said chamber, said container supporting meansand container having interlocking portions for removably supporting said container in operative position, a feed tube between said supporting means and chamber, and a breather tube on said supporting means extending into a supported container to a point above the liquid contents of the container.
3. Means for filling syringe cartridges, including a standard, means providing a chamber adapted to be evacuated mounted on saidstandard, a liquid container, means for removably supporting said container in position for gravital discharge into said chamber, said supporting means and container including interlocking portions to removably secure said container in operative position, a feed tube between said sup porting means and said chamber, a breather tube on said supporting means extending into a supported container to a point above the liquid contents thereof, and means for filtering air admitted to said breather tube.
4. Means for filling syringe cartridges, comprising in combination, a base and a standard, a piston pump removably supported by said standard above the base, said pump having a needle-like discharge nozzle, means carried by said pump for receiving a supply of liquid filler for the cartridge. a duct between said supply and the interior 01 said pump communicating with the pump interior adjacent the active face of the piston when the same is at the end of its stroke in a. direction away from the pump nozzle, means for clamping a cartridge in position to receive fluid from said nozzle, said piston being adjacent the nozzle end of the pump for closing fluid admission to the pump on initiation of the filling operation, movement of the piston away from the nozzle evacuating the cartridge prior to fluid entry and movement of the piston toward the nozzle 5 forcing fluid into said cartridge.
JAMES L. ARMSTRONG.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US684525A US2064815A (en) | 1933-08-10 | 1933-08-10 | Apparatus for filling syringe cartridges and the like |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US684525A US2064815A (en) | 1933-08-10 | 1933-08-10 | Apparatus for filling syringe cartridges and the like |
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US2064815A true US2064815A (en) | 1936-12-22 |
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US684525A Expired - Lifetime US2064815A (en) | 1933-08-10 | 1933-08-10 | Apparatus for filling syringe cartridges and the like |
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Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2693418A (en) * | 1951-07-11 | 1954-11-02 | Edward W Smith | Means and method of filling cans with pressurized substances |
US2726801A (en) * | 1949-09-28 | 1955-12-13 | Henry C Fox | Clock train lubricating method and apparatus |
US3203455A (en) * | 1961-02-20 | 1965-08-31 | Marryat & Place Ltd | Syringe for injecting small measured volumes of liquid |
US3602272A (en) * | 1969-05-07 | 1971-08-31 | Becton Dickinson Co | Manual syringe filling device |
US4311140A (en) * | 1976-05-10 | 1982-01-19 | Henry Bridgman | Vacuum curet having an improved curetting opening |
US4497349A (en) * | 1982-02-08 | 1985-02-05 | Loma Linda University Medical Center | Solution dispenser |
US5494087A (en) * | 1994-10-13 | 1996-02-27 | Pitelka; Karen J. | Apparatus for aiding in the preparation of an injection serum |
WO1996031392A1 (en) * | 1995-04-04 | 1996-10-10 | Allergan | On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling |
DE102006040507A1 (en) * | 2006-03-10 | 2007-09-13 | Tremco Illbruck Productie B.V. | Silicone cartridge`s content color adjustment method for use in catridge pistol, involves allowing colorless silicone from container and coloring material to intersperse in common mixing chamber, before mixture is brought into cartridge |
US20080264261A1 (en) * | 2007-04-30 | 2008-10-30 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US20080269681A1 (en) * | 2007-04-30 | 2008-10-30 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US7963954B2 (en) * | 2007-04-30 | 2011-06-21 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US20120265140A1 (en) * | 2011-04-18 | 2012-10-18 | Thorne Consulting And Intellectual Property, Llc | Medical syrnge prime and cross-contamination free devices |
US8323250B2 (en) | 2007-04-30 | 2012-12-04 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
US8434528B2 (en) | 2007-04-30 | 2013-05-07 | Medtronic Minimed, Inc. | Systems and methods for reservoir filling |
US8597243B2 (en) | 2007-04-30 | 2013-12-03 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US8613725B2 (en) | 2007-04-30 | 2013-12-24 | Medtronic Minimed, Inc. | Reservoir systems and methods |
US9199030B2 (en) | 2005-05-06 | 2015-12-01 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
CN113247330A (en) * | 2020-02-10 | 2021-08-13 | Jvm 有限公司 | Liquid medicine quantitative distribution device |
-
1933
- 1933-08-10 US US684525A patent/US2064815A/en not_active Expired - Lifetime
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2726801A (en) * | 1949-09-28 | 1955-12-13 | Henry C Fox | Clock train lubricating method and apparatus |
US2693418A (en) * | 1951-07-11 | 1954-11-02 | Edward W Smith | Means and method of filling cans with pressurized substances |
US3203455A (en) * | 1961-02-20 | 1965-08-31 | Marryat & Place Ltd | Syringe for injecting small measured volumes of liquid |
US3602272A (en) * | 1969-05-07 | 1971-08-31 | Becton Dickinson Co | Manual syringe filling device |
US4311140A (en) * | 1976-05-10 | 1982-01-19 | Henry Bridgman | Vacuum curet having an improved curetting opening |
US4497349A (en) * | 1982-02-08 | 1985-02-05 | Loma Linda University Medical Center | Solution dispenser |
US5494087A (en) * | 1994-10-13 | 1996-02-27 | Pitelka; Karen J. | Apparatus for aiding in the preparation of an injection serum |
WO1996031392A1 (en) * | 1995-04-04 | 1996-10-10 | Allergan | On-site syringe filling apparatus for viscoelastic materials, and corresponding method for on-site syringe filling |
US9199030B2 (en) | 2005-05-06 | 2015-12-01 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
DE102006040507A1 (en) * | 2006-03-10 | 2007-09-13 | Tremco Illbruck Productie B.V. | Silicone cartridge`s content color adjustment method for use in catridge pistol, involves allowing colorless silicone from container and coloring material to intersperse in common mixing chamber, before mixture is brought into cartridge |
US8025658B2 (en) | 2007-04-30 | 2011-09-27 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
US8597270B2 (en) | 2007-04-30 | 2013-12-03 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US7959715B2 (en) | 2007-04-30 | 2011-06-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US7963954B2 (en) * | 2007-04-30 | 2011-06-21 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US20080269681A1 (en) * | 2007-04-30 | 2008-10-30 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US8083716B2 (en) | 2007-04-30 | 2011-12-27 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US8172929B2 (en) | 2007-04-30 | 2012-05-08 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US10772796B2 (en) | 2007-04-30 | 2020-09-15 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US8323250B2 (en) | 2007-04-30 | 2012-12-04 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
US8434528B2 (en) | 2007-04-30 | 2013-05-07 | Medtronic Minimed, Inc. | Systems and methods for reservoir filling |
US8597243B2 (en) | 2007-04-30 | 2013-12-03 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US20090198215A1 (en) * | 2007-04-30 | 2009-08-06 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
US8613725B2 (en) | 2007-04-30 | 2013-12-24 | Medtronic Minimed, Inc. | Reservoir systems and methods |
US9089641B2 (en) | 2007-04-30 | 2015-07-28 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US20080264261A1 (en) * | 2007-04-30 | 2008-10-30 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
US9205191B2 (en) | 2007-04-30 | 2015-12-08 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US9522225B2 (en) | 2007-04-30 | 2016-12-20 | Medtronic Minimed, Inc. | Adhesive patch systems and methods |
US9901514B2 (en) | 2007-04-30 | 2018-02-27 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US9980879B2 (en) | 2007-04-30 | 2018-05-29 | Medtronic Minimed, Inc. | Automated filling systems and methods |
US20120265140A1 (en) * | 2011-04-18 | 2012-10-18 | Thorne Consulting And Intellectual Property, Llc | Medical syrnge prime and cross-contamination free devices |
CN113247330A (en) * | 2020-02-10 | 2021-08-13 | Jvm 有限公司 | Liquid medicine quantitative distribution device |
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